## Sun Dec 14 22:09:57 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158358_bin.18.fa -m mmseqs --itype genome -o SRR25158358_bin.18 --output_dir /data/result/bins/wyx/egg/SRR25158358_bin.18 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158358_k127_1005786_6	926561.KB900620_gene2917	2.017e-35	152.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WB1B@53433|Halanaerobiales	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158358_k127_1005786_2	926564.KI911656_gene1535	1.94e-118	389.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4F3D6@85017|Promicromonosporaceae	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158358_k127_1005786_1	471853.Bcav_2197	1.795e-154	507.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158358_k127_1005786_3	929712.KI912613_gene2824	1.66e-88	304.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_1005786_0	66377.JOBH01000010_gene6401	0.0	1099.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158358_k127_1005786_5	1499968.TCA2_2476	7.626e-36	144.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,26T6D@186822|Paenibacillaceae	91061|Bacilli	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158358_k127_1005786_4	661478.OP10G_4311	3.354e-62	223.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158358_k127_1007613_1	266117.Rxyl_1158	1.684e-13	73.0	COG4968@1|root,COG4968@2|Bacteria,2I4BD@201174|Actinobacteria,4CU66@84995|Rubrobacteria	84995|Rubrobacteria	NU	Cell motility and secretion Intracellular trafficking and secretion	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158358_k127_1007613_4	742765.HMPREF9457_00027	0.000154	50.0	COG2165@1|root,COG2165@2|Bacteria,1VK8F@1239|Firmicutes,24TBR@186801|Clostridia	186801|Clostridia	U	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158358_k127_1007613_0	1380390.JIAT01000017_gene5297	5.158e-129	425.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158358_k127_1007613_2	656519.Halsa_1436	8.771e-13	82.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes,25DJ0@186801|Clostridia,3WAT5@53433|Halanaerobiales	186801|Clostridia	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158358_k127_1007613_3	1380390.JIAT01000017_gene5278	1.079e-08	65.0	2AVF2@1|root,31M71@2|Bacteria,2HPWF@201174|Actinobacteria,4CRB2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM
SRR25158358_k127_1008795_0	1382306.JNIM01000001_gene2570	1.261e-127	414.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158358_k127_1008795_1	44060.JODL01000024_gene284	4.288e-117	383.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	ppk2	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158358_k127_1008795_2	234267.Acid_6341	2.089e-24	118.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1024344_0	1380390.JIAT01000009_gene364	1.742e-190	607.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158358_k127_1024344_2	1380390.JIAT01000009_gene362	2.821e-128	418.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158358_k127_1024344_4	219305.MCAG_01435	4.405e-80	280.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158358_k127_1024344_1	469383.Cwoe_0086	1.328e-174	568.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4CP9E@84995|Rubrobacteria	84995|Rubrobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158358_k127_1024344_3	469383.Cwoe_5493	2.277e-98	342.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CPAJ@84995|Rubrobacteria	84995|Rubrobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158358_k127_1024344_5	1380390.JIAT01000015_gene5716	4.665e-66	232.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158358_k127_1032374_2	134676.ACPL_733	1.594e-103	353.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4D95N@85008|Micromonosporales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158358_k127_1032374_6	469383.Cwoe_3228	2.359e-34	134.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158358_k127_1032374_0	1449126.JQKL01000001_gene1386	5.677e-214	691.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,2681N@186813|unclassified Clostridiales	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158358_k127_1032374_1	469383.Cwoe_3233	3.077e-144	469.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158358_k127_1032374_4	1380390.JIAT01000010_gene4830	9.21e-53	193.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158358_k127_1032374_5	1238182.C882_4325	4.246e-51	191.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2U70V@28211|Alphaproteobacteria,2JT1J@204441|Rhodospirillales	204441|Rhodospirillales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158358_k127_1032374_3	1380393.JHVP01000003_gene1268	4.26e-77	263.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158358_k127_1035039_3	1121924.ATWH01000008_gene615	2.848e-05	47.0	COG3395@1|root,COG3395@2|Bacteria,2HYP6@201174|Actinobacteria,4FNIS@85023|Microbacteriaceae	201174|Actinobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
SRR25158358_k127_1035039_0	246196.MSMEI_0877	9.907e-62	223.0	COG0191@1|root,COG0191@2|Bacteria,2H640@201174|Actinobacteria,235I5@1762|Mycobacteriaceae	201174|Actinobacteria	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158358_k127_1035039_2	767817.Desgi_1949	7.061e-50	188.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158358_k127_1035039_1	1157637.KB892111_gene4184	5.464e-54	212.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158358_k127_1035039_4	1120950.KB892749_gene3287	0.0005787	45.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4DNCX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1044041_0	469383.Cwoe_3280	1.17e-192	605.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1044041_1	1200352.A606_01055	1.011e-90	309.0	COG1335@1|root,COG1335@2|Bacteria,2I8U4@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158358_k127_1044041_2	1246995.AFR_18435	1.579e-16	81.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4DHIQ@85008|Micromonosporales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158358_k127_1046102_4	314278.NB231_16478	2.748e-140	449.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158358_k127_1046102_0	479434.Sthe_1092	0.0	1400.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158358_k127_1046102_1	309801.trd_1933	4.135e-314	980.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158358_k127_1046102_3	1122939.ATUD01000004_gene3930	1.385e-147	480.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CPER@84995|Rubrobacteria	84995|Rubrobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158358_k127_1046102_6	479431.Namu_3507	7.11e-47	188.0	COG1392@1|root,COG1392@2|Bacteria,2IIE4@201174|Actinobacteria	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158358_k127_1046102_5	1123258.AQXZ01000016_gene2438	5.598e-112	370.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4FW14@85025|Nocardiaceae	201174|Actinobacteria	P	Phosphate transporter family	pitB	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	iNJ661.Rv2281	PHO4
SRR25158358_k127_1046102_2	1205680.CAKO01000029_gene5279	4.301e-222	696.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria,2JVZM@204441|Rhodospirillales	204441|Rhodospirillales	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158358_k127_1061824_4	1449044.JMLE01000003_gene2850	3.681e-46	174.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158358_k127_1061824_0	1307436.PBF_16239	1.219e-226	722.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,1ZDFI@1386|Bacillus	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158358_k127_1061824_3	43354.JOIJ01000040_gene1392	1.058e-48	184.0	COG2186@1|root,COG2186@2|Bacteria,2INJC@201174|Actinobacteria,4EB0H@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_1061824_5	219305.MCAG_00891	2.542e-36	154.0	COG1056@1|root,COG1056@2|Bacteria,2GRY1@201174|Actinobacteria	201174|Actinobacteria	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158358_k127_1061824_1	1120948.KB903244_gene2747	9.348e-93	319.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria,4E72B@85010|Pseudonocardiales	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158358_k127_1061824_2	222534.KB893722_gene518	1.156e-59	224.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,4EX2K@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158358_k127_1061824_6	675635.Psed_6293	6.309e-18	88.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4E9VP@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	caiA	-	1.3.8.13	ko:K08297,ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_1063117_3	1380390.JIAT01000009_gene2098	3.073e-20	102.0	COG2866@1|root,COG2866@2|Bacteria,2HPMB@201174|Actinobacteria,4CQZA@84995|Rubrobacteria	84995|Rubrobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158358_k127_1063117_5	648757.Rvan_2488	6.713e-06	57.0	COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,2TR3K@28211|Alphaproteobacteria,3N7V8@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	PFAM peptidase U6 penicillin-insensitive murein endopeptidase	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
SRR25158358_k127_1063117_1	1306174.JODP01000020_gene380	3.382e-43	166.0	2ASGX@1|root,31HX4@2|Bacteria,2IFWG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1063117_0	1131814.JAFO01000001_gene1519	3.364e-65	228.0	28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,2TTW0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AA_synth
SRR25158358_k127_1063117_2	1367847.JCM7686_1840	1.142e-27	121.0	arCOG10157@1|root,3220G@2|Bacteria,1R2VK@1224|Proteobacteria	1224|Proteobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	MmlI
SRR25158358_k127_1063117_4	1122939.ATUD01000004_gene3845	1.547e-07	60.0	COG1834@1|root,COG1834@2|Bacteria	2|Bacteria	E	dimethylargininase activity	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158358_k127_1067123_0	935866.JAER01000009_gene771	2.493e-149	481.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4DPMF@85009|Propionibacteriales	201174|Actinobacteria	U	Type II/IV secretion system protein	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158358_k127_1067123_4	1306174.JODP01000009_gene6554	1.712e-39	161.0	COG4965@1|root,COG4965@2|Bacteria,2H577@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF,VWA_2
SRR25158358_k127_1067123_2	643648.Slip_1917	8.948e-46	177.0	COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,24GQ4@186801|Clostridia,42KJZ@68298|Syntrophomonadaceae	186801|Clostridia	NU	PFAM type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158358_k127_1067123_3	211165.AJLN01000040_gene6453	1.327e-39	153.0	COG1846@1|root,COG1846@2|Bacteria,1G5RS@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158358_k127_1067123_5	192952.MM_3140	1.846e-32	135.0	COG4635@1|root,arCOG00524@2157|Archaea,2Y1YN@28890|Euryarchaeota,2NB42@224756|Methanomicrobia	224756|Methanomicrobia	C	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158358_k127_1067123_1	1298863.AUEP01000013_gene4093	1.21e-57	206.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4DT97@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRR25158358_k127_1074707_5	1380390.JIAT01000011_gene2343	6.554e-17	81.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158358_k127_1074707_0	926550.CLDAP_40500	9.255e-70	245.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158358_k127_1074707_6	1283299.AUKG01000003_gene257	1.566e-13	82.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158358_k127_1074707_2	1504319.GM45_4820	5.908e-56	213.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,3UWVR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158358_k127_1074707_3	523841.HFX_2401	1.713e-54	203.0	COG1121@1|root,arCOG00201@2157|Archaea,2XTEU@28890|Euryarchaeota,23SAC@183963|Halobacteria	183963|Halobacteria	E	COG1121 ABC-type Mn Zn transport systems, ATPase component	znuC1	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158358_k127_1074707_1	356851.JOAN01000031_gene5315	2.626e-59	216.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4D9QD@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	scbA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158358_k127_1074707_4	469383.Cwoe_4742	7.812e-48	175.0	COG0735@1|root,COG0735@2|Bacteria,2HTHG@201174|Actinobacteria,4CSV2@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158358_k127_1082231_2	1444309.JAQG01000131_gene3969	6.238e-08	55.0	2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4HZXQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1082231_1	1449076.JOOE01000001_gene1983	4.384e-33	140.0	COG3217@1|root,COG3217@2|Bacteria,1Q80R@1224|Proteobacteria,2VE68@28211|Alphaproteobacteria,2K30Y@204457|Sphingomonadales	204457|Sphingomonadales	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MOSC_N
SRR25158358_k127_1082231_0	469383.Cwoe_4683	4.867e-146	473.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_1084978_0	555079.Toce_1709	1.186e-169	549.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,42ETW@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158358_k127_1084978_1	1206720.BAFQ01000150_gene3925	1.004e-21	108.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4G24K@85025|Nocardiaceae	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158358_k127_1092131_0	1283299.AUKG01000001_gene2130	1.769e-242	801.0	COG2206@1|root,COG2373@1|root,COG2206@2|Bacteria,COG2373@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158358_k127_1092131_3	869210.Marky_1369	2.86e-51	190.0	COG2151@1|root,COG2151@2|Bacteria,1WJW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158358_k127_1092131_4	479434.Sthe_2569	2.956e-41	161.0	COG3396@1|root,COG3396@2|Bacteria,2G9KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158358_k127_1092131_6	479434.Sthe_2568	3.892e-11	69.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR25158358_k127_1092131_1	869210.Marky_1366	5.261e-136	438.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158358_k127_1092131_2	469383.Cwoe_2195	3.788e-55	203.0	COG1309@1|root,COG1309@2|Bacteria,2GMNZ@201174|Actinobacteria,4CTR3@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158358_k127_1092131_5	324602.Caur_3844	1.9e-19	93.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi,375GG@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158358_k127_1095745_3	395961.Cyan7425_3874	1.78e-14	86.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,3KI02@43988|Cyanothece	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158358_k127_1095745_0	886293.Sinac_5449	8.11e-110	383.0	COG0381@1|root,COG0381@2|Bacteria,2IWR6@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158358_k127_1095745_1	469383.Cwoe_0096	4.737e-87	301.0	COG1215@1|root,COG1215@2|Bacteria,2GXGY@201174|Actinobacteria,4CS4U@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158358_k127_1095745_2	469383.Cwoe_0097	6.016e-49	186.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CQ5U@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158358_k127_1098678_0	1238182.C882_0216	1.143e-64	234.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2TVZ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158358_k127_1098678_1	1128421.JAGA01000004_gene2555	3.171e-51	188.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15,2.7.7.42,2.7.7.89	ko:K00982,ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158358_k127_1098678_4	1283299.AUKG01000002_gene4071	1.851e-07	61.0	2AUSG@1|root,31KFH@2|Bacteria,2HPAB@201174|Actinobacteria,4CQNM@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1098678_2	1071679.BG57_22655	6.485e-38	160.0	COG1520@1|root,COG1520@2|Bacteria,1PIDA@1224|Proteobacteria,2W71D@28216|Betaproteobacteria,1K61Z@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158358_k127_1098678_3	330214.NIDE3081	4.182e-35	138.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158358_k127_1111493_2	469383.Cwoe_0090	2.476e-26	125.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158358_k127_1111493_0	1242864.D187_008264	3.256e-119	391.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K00001,ko:K07119	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N_2,ADH_zinc_N
SRR25158358_k127_1111493_3	1161401.ASJA01000027_gene48	6.263e-19	89.0	COG3360@1|root,COG3360@2|Bacteria,1PURU@1224|Proteobacteria,2V0YI@28211|Alphaproteobacteria,43YVT@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	-	-	-	-	-	-	-	-	-	Dodecin
SRR25158358_k127_1111493_1	1128421.JAGA01000002_gene1341	2.217e-44	173.0	COG0159@1|root,COG0159@2|Bacteria,2NP9W@2323|unclassified Bacteria	2|Bacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158358_k127_1111493_4	1382303.JPOM01000001_gene1992	3.879e-15	77.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,2KFB5@204458|Caulobacterales	204458|Caulobacterales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158358_k127_1115616_2	1283299.AUKG01000002_gene4773	8.778e-23	98.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_1115616_0	671143.DAMO_0568	9.062e-194	627.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158358_k127_1115616_1	469383.Cwoe_3662	9.46e-24	109.0	2AT5U@1|root,31IN3@2|Bacteria,2HN2Z@201174|Actinobacteria,4CQH5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_111665_0	118173.KB235914_gene858	7.445e-106	346.0	COG0376@1|root,COG0376@2|Bacteria,1G1NM@1117|Cyanobacteria,1H83F@1150|Oscillatoriales	1117|Cyanobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158358_k127_111665_2	1380390.JIAT01000011_gene2493	1.828e-56	218.0	COG2199@1|root,COG3706@2|Bacteria,2HFRC@201174|Actinobacteria,4CR17@84995|Rubrobacteria	84995|Rubrobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
SRR25158358_k127_111665_1	1287116.X734_18995	2.103e-71	269.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158358_k127_111665_3	702113.PP1Y_Mpl2357	3.616e-15	86.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_112252_0	1122939.ATUD01000009_gene3003	5.779e-157	512.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CQ79@84995|Rubrobacteria	84995|Rubrobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158358_k127_112252_1	929712.KI912613_gene2663	2.345e-62	223.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CPR6@84995|Rubrobacteria	84995|Rubrobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158358_k127_112252_2	1283299.AUKG01000003_gene560	5.865e-60	228.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158358_k127_112252_3	1121468.AUBR01000004_gene192	3.56e-28	131.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,42GD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158358_k127_1131961_1	1040986.ATYO01000011_gene5512	2.762e-66	241.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158358_k127_1131961_0	1380390.JIAT01000014_gene6050	1.111e-96	340.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158358_k127_1131961_2	35754.JNYJ01000006_gene5196	4.376e-52	203.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D9Z5@85008|Micromonosporales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158358_k127_1141125_3	1122933.JNIY01000003_gene564	3.17e-11	65.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4F14X@85016|Cellulomonadaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158358_k127_1141125_0	1380390.JIAT01000009_gene1098	3.99e-44	169.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria	201174|Actinobacteria	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158358_k127_1141125_2	330214.NIDE4014	1.064e-35	151.0	2EUIU@1|root,33N0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1141125_1	469383.Cwoe_3625	1.319e-36	143.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_115046_1	1122182.KB903833_gene5401	4.752e-46	189.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158358_k127_115046_0	1121468.AUBR01000029_gene1549	3.759e-172	556.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42F33@68295|Thermoanaerobacterales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158358_k127_1151758_2	1111069.TCCBUS3UF1_12040	2.575e-36	141.0	COG0160@1|root,COG0160@2|Bacteria,1WIP2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158358_k127_1151758_0	469383.Cwoe_0018	3.185e-81	287.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158358_k127_1151758_1	485913.Krac_8072	6.842e-81	286.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
SRR25158358_k127_1154199_3	1349767.GJA_2097	9.769e-47	171.0	COG0406@1|root,COG0406@2|Bacteria,1R62X@1224|Proteobacteria,2VKQ1@28216|Betaproteobacteria,473DI@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158358_k127_1154199_2	1120936.KB907208_gene1214	5.003e-84	298.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4EJ41@85012|Streptosporangiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158358_k127_1154199_1	1123368.AUIS01000007_gene2717	5.919e-184	593.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1S6M5@1236|Gammaproteobacteria,2NBV4@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158358_k127_1154199_0	1128421.JAGA01000002_gene1742	3.766e-187	602.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158358_k127_1154433_1	469383.Cwoe_2658	7.544e-138	441.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158358_k127_1154433_4	1064535.MELS_1534	2.362e-29	129.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4H2TV@909932|Negativicutes	909932|Negativicutes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158358_k127_1154433_2	469383.Cwoe_2661	2.554e-109	380.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158358_k127_1154433_3	1283299.AUKG01000005_gene60	7.736e-84	292.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158358_k127_1154433_6	661087.HMPREF1008_01367	0.0002302	54.0	COG3597@1|root,COG3597@2|Bacteria,2GZU9@201174|Actinobacteria,4CVH2@84998|Coriobacteriia	84998|Coriobacteriia	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
SRR25158358_k127_1154433_0	469383.Cwoe_2663	4.982e-154	517.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CPSJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158358_k127_1159684_2	1122939.ATUD01000007_gene1992	1.864e-96	329.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158358_k127_1159684_10	1380390.JIAT01000013_gene230	8.134e-21	102.0	COG0662@1|root,COG0662@2|Bacteria,2HR0E@201174|Actinobacteria,4CSU6@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1159684_12	1463895.JODA01000053_gene3342	2.92e-14	83.0	COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1159684_11	1463887.KL590004_gene1898	3.384e-17	85.0	2E7GB@1|root,331Z4@2|Bacteria,2GUP0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1159684_14	1283299.AUKG01000002_gene4285	2.982e-09	68.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1159684_4	469383.Cwoe_4251	1.461e-75	278.0	COG0389@1|root,COG0389@2|Bacteria,2HPPZ@201174|Actinobacteria,4CR2N@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS
SRR25158358_k127_1159684_5	196162.Noca_0360	2.253e-62	224.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,4DQJ7@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158358_k127_1159684_8	1121428.DESHY_60306___1	5.996e-34	139.0	COG2045@1|root,COG2045@2|Bacteria,1V56I@1239|Firmicutes,248U8@186801|Clostridia,261K1@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158358_k127_1159684_7	1169154.KB897777_gene3823	3.48e-51	196.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158358_k127_1159684_0	935839.JAGJ01000004_gene1885	0.0	1046.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4F3Q8@85017|Promicromonosporaceae	201174|Actinobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158358_k127_1159684_9	1463825.JNXC01000022_gene700	4.089e-33	149.0	COG0563@1|root,COG0563@2|Bacteria,2IJ2R@201174|Actinobacteria,4E56K@85010|Pseudonocardiales	201174|Actinobacteria	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
SRR25158358_k127_1159684_6	478801.Ksed_17550	5.365e-62	223.0	COG1806@1|root,COG1806@2|Bacteria,2HUIK@201174|Actinobacteria,1ZX45@145357|Dermacoccaceae	201174|Actinobacteria	S	Kinase/pyrophosphorylase	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
SRR25158358_k127_1159684_3	765910.MARPU_16635	9.69e-92	325.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales	135613|Chromatiales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRR25158358_k127_1159684_1	395494.Galf_2101	2.872e-122	401.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,44VDK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRR25158358_k127_1159684_13	1380390.JIAT01000003_gene5463	5.744e-13	72.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158358_k127_1164630_2	55952.BU52_21120	1.057e-36	145.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158358_k127_1164630_4	469383.Cwoe_3210	4.113e-23	110.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4CQGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158358_k127_1164630_1	1122939.ATUD01000005_gene2711	9.323e-45	174.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158358_k127_1164630_3	469383.Cwoe_3207	2.583e-34	135.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1164630_0	1408437.JNJN01000003_gene1538	5.739e-60	222.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,25USG@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158358_k127_1164630_5	309798.COPRO5265_1315	3.464e-12	70.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes	1239|Firmicutes	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
SRR25158358_k127_1172023_3	929712.KI912613_gene4811	6.441e-23	101.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158358_k127_1172023_1	502025.Hoch_2148	5.488e-59	216.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158358_k127_1172023_0	42256.RradSPS_2243	9.64e-83	285.0	COG0813@1|root,COG0813@2|Bacteria,2GNT6@201174|Actinobacteria,4CU45@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158358_k127_1172023_2	1122611.KB903987_gene3983	2.389e-29	127.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4EFMK@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158358_k127_1188204_4	868864.Dester_0088	4.442e-46	175.0	COG2074@1|root,COG2074@2|Bacteria,2G4F4@200783|Aquificae	200783|Aquificae	G	ATP cone domain	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	ATP-cone
SRR25158358_k127_1188204_2	401526.TcarDRAFT_0978	9.221e-80	277.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H22D@909932|Negativicutes	909932|Negativicutes	G	fructose-1,6-bisphosphatase	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158358_k127_1188204_6	1122939.ATUD01000002_gene1242	1.638e-27	115.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CQHE@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158358_k127_1188204_5	1246995.AFR_08775	1.883e-41	164.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4DCGZ@85008|Micromonosporales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158358_k127_1188204_0	35754.JNYJ01000042_gene1350	2.11e-95	321.0	COG4152@1|root,COG4152@2|Bacteria,2I2U6@201174|Actinobacteria,4DMD2@85008|Micromonosporales	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	AAA_21,ABC_tran,DUF4162
SRR25158358_k127_1188204_1	374847.Kcr_0359	1.289e-81	282.0	COG0604@1|root,arCOG01458@2157|Archaea	2157|Archaea	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1188204_3	1329516.JPST01000019_gene2702	7.815e-47	178.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,27B60@186824|Thermoactinomycetaceae	91061|Bacilli	C	4Fe-4S double cluster binding domain	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SRR25158358_k127_1193424_3	266117.Rxyl_0001	4.186e-20	90.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CPFC@84995|Rubrobacteria	84995|Rubrobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158358_k127_1193424_1	469383.Cwoe_0002	2.21e-102	346.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158358_k127_1193424_2	1380390.JIAT01000009_gene1789	2.292e-64	241.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CQ4U@84995|Rubrobacteria	84995|Rubrobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
SRR25158358_k127_1193424_4	469383.Cwoe_0004	1.487e-06	57.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158358_k127_1193424_0	479436.Vpar_0007	7.82e-208	668.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H2D7@909932|Negativicutes	909932|Negativicutes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158358_k127_1199311_2	698761.RTCIAT899_CH16060	1.375e-10	63.0	COG1846@1|root,COG1846@2|Bacteria,1NJH3@1224|Proteobacteria,2U067@28211|Alphaproteobacteria,4BEXQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
SRR25158358_k127_1199311_1	1133849.O3I_010610	2.745e-56	203.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158358_k127_1199311_3	1304880.JAGB01000001_gene67	0.0006326	49.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158358_k127_1199311_0	469383.Cwoe_0106	1.377e-61	219.0	COG0741@1|root,COG0741@2|Bacteria,2HQ39@201174|Actinobacteria,4CRJS@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158358_k127_1201422_4	469383.Cwoe_2902	1.054e-82	279.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
SRR25158358_k127_1201422_5	42256.RradSPS_0987	3.926e-67	245.0	COG0297@1|root,COG0297@2|Bacteria,2I4BF@201174|Actinobacteria,4CU41@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158358_k127_1201422_3	469383.Cwoe_2903	3.024e-112	389.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158358_k127_1201422_0	1123377.AUIV01000012_gene702	1.771e-267	839.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales	135614|Xanthomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158358_k127_1201422_8	1380390.JIAT01000016_gene5499	8.316e-32	129.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4CQ18@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158358_k127_1201422_6	929712.KI912613_gene4284	6.543e-61	222.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CPKV@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158358_k127_1201422_2	1448860.BBJO01000024_gene3071	3.931e-144	473.0	COG0168@1|root,arCOG04145@2157|Archaea,2XT89@28890|Euryarchaeota,23TBX@183963|Halobacteria	183963|Halobacteria	P	COG0168 Trk-type K transport systems, membrane components	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158358_k127_1201422_1	469383.Cwoe_3474	1.812e-149	490.0	COG0168@1|root,COG0168@2|Bacteria,2HNZI@201174|Actinobacteria,4CQ92@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158358_k127_1201422_7	469383.Cwoe_3473	1.877e-53	194.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CQH1@84995|Rubrobacteria	84995|Rubrobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158358_k127_120194_0	675635.Psed_2559	1.637e-111	371.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3,1.5.99.4	ko:K03520,ko:K19820	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_120194_2	292564.Cyagr_2355	2.498e-53	203.0	COG1600@1|root,COG1600@2|Bacteria,1G07Y@1117|Cyanobacteria,22TAF@167375|Cyanobium	1117|Cyanobacteria	C	Reductive dehalogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase,Fer4,Fer4_7,SCP2
SRR25158358_k127_120194_3	1123023.JIAI01000001_gene7740	5.756e-41	162.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria,4EBTB@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_120194_1	1380390.JIAT01000012_gene3025	4.537e-67	236.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,4CS7U@84995|Rubrobacteria	84995|Rubrobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1210010_1	882086.SacxiDRAFT_3986	1.03e-13	81.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4E03G@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158358_k127_1210010_0	765420.OSCT_0449	3.646e-47	175.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158358_k127_1220427_3	1231185.BAMP01000090_gene2462	1.059e-38	146.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,2UA4V@28211|Alphaproteobacteria,43RCI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1220427_6	243924.LT42_11750	4.317e-26	111.0	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11022	ko05134,map05134	-	-	-	ko00000,ko00001,ko02042	-	-	-	-
SRR25158358_k127_1220427_4	867903.ThesuDRAFT_00795	1.597e-33	134.0	COG0328@1|root,COG2384@1|root,COG0328@2|Bacteria,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3WDGE@538999|Clostridiales incertae sedis	186801|Clostridia	L	tRNA (adenine(22)-N(1))-methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
SRR25158358_k127_1220427_5	926550.CLDAP_08630	2.205e-26	121.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158358_k127_1220427_7	469371.Tbis_3575	9.884e-11	70.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria,4DZGX@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158358_k127_1220427_8	35754.JNYJ01000029_gene9508	1.274e-05	55.0	2B9SB@1|root,32350@2|Bacteria,2H7QG@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158358_k127_1220427_1	2074.JNYD01000024_gene2861	5.165e-60	240.0	COG0745@1|root,COG3629@1|root,COG0745@2|Bacteria,COG3629@2|Bacteria,2GKKQ@201174|Actinobacteria,4E498@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158358_k127_1220427_2	710686.Mycsm_03499	2.458e-39	171.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,2334C@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158358_k127_1220427_0	1449976.KALB_6965	2.041e-141	504.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4E8I6@85010|Pseudonocardiales	201174|Actinobacteria	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
SRR25158358_k127_1229052_2	330084.JNYZ01000015_gene6045	9.508e-44	182.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_1229052_0	1366050.N234_03045	1.766e-145	487.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2VK8C@28216|Betaproteobacteria,1KHE8@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158358_k127_1229052_1	477641.MODMU_2718	7.238e-47	175.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2I8W5@201174|Actinobacteria	201174|Actinobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158358_k127_1229631_5	1536772.R70723_09205	3.788e-10	63.0	COG0477@1|root,COG0477@2|Bacteria,1UXX6@1239|Firmicutes,4HF8Y@91061|Bacilli,26TS2@186822|Paenibacillaceae	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_1229631_6	221288.JH992901_gene2993	9.41e-07	56.0	COG0432@1|root,COG0432@2|Bacteria,1G5WN@1117|Cyanobacteria,1JKIB@1189|Stigonemataceae	1117|Cyanobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158358_k127_1229631_2	298655.KI912266_gene17	1.645e-86	300.0	COG1562@1|root,COG1562@2|Bacteria,2GNS9@201174|Actinobacteria,4EV51@85013|Frankiales	201174|Actinobacteria	I	PFAM Squalene phytoene synthase	hopE	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR25158358_k127_1229631_3	222534.KB893761_gene3493	2.837e-83	293.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4ESDE@85013|Frankiales	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158358_k127_1229631_1	1146883.BLASA_0213	1.999e-133	441.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria,4ERME@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158358_k127_1229631_0	2002.JOEQ01000031_gene1587	1.119e-272	861.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,4EFV5@85012|Streptosporangiales	201174|Actinobacteria	I	Squalene-hopene cyclase N-terminal domain	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
SRR25158358_k127_1229631_4	1120950.KB892742_gene2981	1.372e-24	111.0	COG0761@1|root,COG0775@1|root,COG0761@2|Bacteria,COG0775@2|Bacteria,2GIZ7@201174|Actinobacteria,4DP9P@85009|Propionibacteriales	201174|Actinobacteria	IM	LytB protein	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,PNP_UDP_1
SRR25158358_k127_1237841_1	1123405.AUMM01000028_gene1406	2.184e-54	192.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26N9U@186821|Sporolactobacillaceae	91061|Bacilli	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1237841_0	1329516.JPST01000030_gene2903	2.646e-107	362.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,27BD9@186824|Thermoactinomycetaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_1237841_2	408672.NBCG_02356	3.325e-52	207.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DN8K@85009|Propionibacteriales	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158358_k127_1237841_4	649638.Trad_1382	2.499e-22	102.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158358_k127_1237841_3	469383.Cwoe_1664	3.109e-39	149.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158358_k127_1238897_5	1380390.JIAT01000010_gene4259	1.695e-17	89.0	COG0806@1|root,COG0806@2|Bacteria,2HR1Q@201174|Actinobacteria,4CSW0@84995|Rubrobacteria	84995|Rubrobacteria	J	RimM N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RimM
SRR25158358_k127_1238897_4	867903.ThesuDRAFT_00296	1.933e-18	87.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3WDJD@538999|Clostridiales incertae sedis	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158358_k127_1238897_3	469383.Cwoe_3682	2.796e-30	121.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CQNJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158358_k127_1238897_0	756499.Desde_3246	7.584e-147	477.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2610F@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158358_k127_1238897_1	469383.Cwoe_3686	2.619e-102	347.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CPF9@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158358_k127_1238897_2	469383.Cwoe_3688	2.014e-69	255.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158358_k127_1240028_1	1245469.S58_28530	2.012e-10	72.0	COG4641@1|root,COG4641@2|Bacteria,1RK42@1224|Proteobacteria,2U7VU@28211|Alphaproteobacteria,3JZKD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
SRR25158358_k127_1240028_0	1172180.KB911778_gene4916	3.129e-99	342.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158358_k127_1243529_6	693661.Arcve_1756	1.333e-21	99.0	COG1051@1|root,arCOG01075@2157|Archaea,2Y7CI@28890|Euryarchaeota,246AK@183980|Archaeoglobi	183980|Archaeoglobi	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158358_k127_1243529_1	1356854.N007_06710	2.259e-62	226.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,277Y5@186823|Alicyclobacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158358_k127_1243529_3	469383.Cwoe_5865	1.729e-40	153.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158358_k127_1243529_0	1380390.JIAT01000009_gene1924	2.728e-154	507.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CRWP@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158358_k127_1243529_5	1408473.JHXO01000005_gene1511	3.956e-27	119.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,MerR_1
SRR25158358_k127_1243529_2	1380390.JIAT01000009_gene1918	5.344e-59	221.0	COG3872@1|root,COG3872@2|Bacteria,2HQG9@201174|Actinobacteria,4CS1C@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158358_k127_1243529_4	1283299.AUKG01000004_gene1034	2.662e-33	137.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PRK
SRR25158358_k127_1243529_7	1157490.EL26_08190	1.298e-15	80.0	COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli	91061|Bacilli	EH	4-amino-4-deoxychorismate lyase	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158358_k127_1247055_0	1146883.BLASA_0283	4.794e-101	339.0	COG3367@1|root,COG3367@2|Bacteria,2IBUZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SRR25158358_k127_1247055_1	1144275.COCOR_00844	7.612e-37	143.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Mandelate racemase muconate lactonizing	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_1248989_1	1123258.AQXZ01000015_gene4475	6.577e-87	299.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FVM6@85025|Nocardiaceae	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158358_k127_1248989_0	1121920.AUAU01000001_gene2276	4.83e-87	299.0	COG0825@1|root,COG0825@2|Bacteria,3Y34D@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158358_k127_1248989_2	221360.RS9917_12085	2.562e-73	256.0	COG0777@1|root,COG0777@2|Bacteria,1G1ZY@1117|Cyanobacteria,1GZU0@1129|Synechococcus	1117|Cyanobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD	Carboxyl_trans
SRR25158358_k127_1248989_3	1451261.AS96_03910	5.9e-26	113.0	COG0010@1|root,COG0010@2|Bacteria,2ICCX@201174|Actinobacteria,4FMMS@85023|Microbacteriaceae	201174|Actinobacteria	E	Arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158358_k127_1249107_5	1122239.AULS01000026_gene2236	1.095e-74	264.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4FN3G@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158358_k127_1249107_3	469383.Cwoe_2889	3.656e-91	313.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4CQ9E@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158358_k127_1249107_2	1380347.JNII01000001_gene4471	1.462e-133	457.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4ERVM@85013|Frankiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS
SRR25158358_k127_1249107_0	469383.Cwoe_2882	0.0	1348.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158358_k127_1249107_7	710421.Mycch_1621	2.094e-18	92.0	2956B@1|root,2ZSIU@2|Bacteria,2ISPI@201174|Actinobacteria,23B2N@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1249107_8	1122138.AQUZ01000017_gene6660	4.383e-14	79.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2,SnoaL_3
SRR25158358_k127_1249107_6	123899.JPQP01000002_gene1068	1.698e-30	134.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2VHKF@28216|Betaproteobacteria,3T3Y0@506|Alcaligenaceae	28216|Betaproteobacteria	L	Calcineurin-like phosphoesterase superfamily domain	cpdA	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158358_k127_1249107_1	469383.Cwoe_5282	2.389e-153	498.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158358_k127_1249107_4	1283299.AUKG01000001_gene2408	2.741e-89	302.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4CR20@84995|Rubrobacteria	84995|Rubrobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158358_k127_1260408_1	502025.Hoch_5598	8.465e-08	64.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,432DI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158358_k127_1260408_0	591158.SSMG_04071	1.135e-136	459.0	COG0154@1|root,COG0154@2|Bacteria,2GUUU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amdA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158358_k127_1264393_1	404589.Anae109_2522	2.788e-62	228.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158358_k127_1264393_0	748247.AZKH_p0217	2.033e-104	348.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VI4P@28216|Betaproteobacteria,2KXV5@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158358_k127_1265635_2	1236689.MMALV_10910	2.012e-06	55.0	COG0517@1|root,arCOG00601@2157|Archaea,2Y890@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158358_k127_1265635_1	1120949.KB903303_gene6731	9.679e-24	115.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_8
SRR25158358_k127_1265635_0	266117.Rxyl_2934	1.886e-33	139.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158358_k127_1270462_3	67373.JOBF01000012_gene3910	5.392e-53	188.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158358_k127_1270462_4	1267005.KB911256_gene2042	3.026e-09	61.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,3N72T@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158358_k127_1270462_0	1283299.AUKG01000003_gene502	1.219e-75	260.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158358_k127_1270462_2	1283299.AUKG01000003_gene505	1.099e-60	218.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CPEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158358_k127_1270462_1	316278.SynRCC307_0068	1.383e-68	247.0	COG0136@1|root,COG0136@2|Bacteria,1G0E6@1117|Cyanobacteria,1GYKG@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158358_k127_1270462_6	1530186.JQEY01000001_gene893	0.0004918	50.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158358_k127_1270462_5	1214101.BN159_1174	3.081e-05	55.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158358_k127_1274480_2	452652.KSE_16980	1.643e-11	72.0	2AN8T@1|root,327DN@2|Bacteria,2I81P@201174|Actinobacteria,2M393@2063|Kitasatospora	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158358_k127_1274480_3	929712.KI912613_gene1158	3.442e-10	72.0	COG0823@1|root,COG0823@2|Bacteria,2HNKQ@201174|Actinobacteria,4CPPF@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
SRR25158358_k127_1274480_0	469383.Cwoe_0979	1.263e-62	243.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158358_k127_1274480_1	887898.HMPREF0551_2353	6.322e-59	217.0	COG2120@1|root,COG2120@2|Bacteria,1MX2V@1224|Proteobacteria,2VYM0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158358_k127_1279352_10	867903.ThesuDRAFT_00739	4.392e-28	115.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158358_k127_1279352_11	1996.JOFO01000013_gene3410	6.412e-18	84.0	COG3813@1|root,COG3813@2|Bacteria,2GRIY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
SRR25158358_k127_1279352_2	344747.PM8797T_12568	4.572e-86	292.0	COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158358_k127_1279352_3	933801.Ahos_1566	1.757e-81	280.0	COG0434@1|root,arCOG01982@2157|Archaea,2XQUF@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
SRR25158358_k127_1279352_7	929712.KI912613_gene970	1.139e-36	154.0	COG2411@1|root,COG2411@2|Bacteria,2HNQQ@201174|Actinobacteria,4CPX9@84995|Rubrobacteria	84995|Rubrobacteria	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158358_k127_1279352_1	383372.Rcas_0181	1.06e-103	345.0	COG0451@1|root,COG0451@2|Bacteria,2G87T@200795|Chloroflexi	200795|Chloroflexi	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158358_k127_1279352_6	215803.DB30_0160	2.331e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,1QX3X@1224|Proteobacteria,437EV@68525|delta/epsilon subdivisions,2X2M4@28221|Deltaproteobacteria,2YZWY@29|Myxococcales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158358_k127_1279352_9	1121934.AUDX01000003_gene903	2.826e-30	122.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4FP1U@85023|Microbacteriaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158358_k127_1279352_0	1380390.JIAT01000009_gene2035	2.146e-276	858.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CP8M@84995|Rubrobacteria	84995|Rubrobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158358_k127_1279352_5	287986.DV20_07070	1.273e-58	218.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DXH4@85010|Pseudonocardiales	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158358_k127_1279352_4	1380390.JIAT01000007_gene5191	2.51e-67	235.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4CR1P@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158358_k127_1279352_8	266117.Rxyl_0173	9.641e-33	137.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158358_k127_1289512_3	1410653.JHVC01000042_gene2108	4.302e-07	60.0	2EGNI@1|root,33AEP@2|Bacteria,1UI2S@1239|Firmicutes,24QAA@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
SRR25158358_k127_1289512_1	469383.Cwoe_3801	4.153e-26	119.0	28RTZ@1|root,2ZE6B@2|Bacteria,2HQNJ@201174|Actinobacteria,4CS8Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
SRR25158358_k127_1289512_2	760568.Desku_2238	1.564e-12	79.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158358_k127_1289512_0	1283299.AUKG01000002_gene4573	1.841e-93	326.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158358_k127_1295246_3	1071085.KK033114_gene910	9.353e-06	48.0	COG1804@1|root,arCOG02304@2157|Archaea,2XTW7@28890|Euryarchaeota,23TTT@183963|Halobacteria	183963|Halobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158358_k127_1295246_2	1169143.KB911046_gene317	2.789e-90	306.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,1K3V2@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158358_k127_1295246_1	1068978.AMETH_5512	5.652e-156	507.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4DZY3@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158358_k127_1295246_0	1123023.JIAI01000007_gene1779	6.233e-180	575.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4DY4S@85010|Pseudonocardiales	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_1301875_0	258533.BN977_01794	5.447e-84	288.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,23882@1762|Mycobacteriaceae	201174|Actinobacteria	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158358_k127_1301875_1	304371.MCP_0851	3.189e-36	142.0	COG0463@1|root,arCOG00896@2157|Archaea,2XT4C@28890|Euryarchaeota,2N9AQ@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158358_k127_1312775_2	457425.XNR_4434	6.967e-55	200.0	COG3483@1|root,COG3483@2|Bacteria,2ICER@201174|Actinobacteria	201174|Actinobacteria	E	Tryptophan 2,3-dioxygenase	-	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158358_k127_1312775_0	1313172.YM304_26410	2.778e-125	416.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158358_k127_1312775_1	882086.SacxiDRAFT_0469	7.615e-61	220.0	COG1251@1|root,COG1251@2|Bacteria,2I3CF@201174|Actinobacteria,4EE7M@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158358_k127_1312986_6	1009370.ALO_10039	2.804e-35	152.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4H1VN@909932|Negativicutes	909932|Negativicutes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	AMIN,NAGPA
SRR25158358_k127_1312986_0	760568.Desku_1548	5.073e-125	410.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia,2609W@186807|Peptococcaceae	186801|Clostridia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158358_k127_1312986_5	292459.STH819	1.697e-37	157.0	COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,24CGN@186801|Clostridia	186801|Clostridia	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158358_k127_1312986_2	485913.Krac_9606	5.549e-65	235.0	COG2267@1|root,COG2267@2|Bacteria,2G8RT@200795|Chloroflexi	200795|Chloroflexi	I	Alpha/beta hydrolase family	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
SRR25158358_k127_1312986_1	498761.HM1_1947	2.915e-112	377.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158358_k127_1312986_3	469383.Cwoe_5924	5.036e-53	199.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158358_k127_1312986_4	309801.trd_A0909	1.031e-51	191.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi,27YB5@189775|Thermomicrobia	189775|Thermomicrobia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158358_k127_1312986_7	234267.Acid_4576	0.0007178	45.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158358_k127_1323031_2	1380390.JIAT01000016_gene5611	2.134e-89	308.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158358_k127_1323031_5	479431.Namu_5330	2.414e-42	162.0	COG2865@1|root,COG2865@2|Bacteria,2IFGR@201174|Actinobacteria	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR25158358_k127_1323031_6	1283299.AUKG01000001_gene2806	1.383e-27	121.0	COG0278@1|root,COG0278@2|Bacteria,2HQWM@201174|Actinobacteria,4CSPM@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158358_k127_1323031_9	1183438.GKIL_2197	4.984e-14	74.0	COG5007@1|root,COG5007@2|Bacteria,1GRBE@1117|Cyanobacteria	1117|Cyanobacteria	K	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
SRR25158358_k127_1323031_4	316274.Haur_1523	8.325e-57	210.0	2F63Z@1|root,33YN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1323031_0	351607.Acel_1394	0.0	1215.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158358_k127_1323031_3	357808.RoseRS_2771	1.29e-85	299.0	COG1457@1|root,COG1457@2|Bacteria,2G9KC@200795|Chloroflexi,376PN@32061|Chloroflexia	32061|Chloroflexia	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
SRR25158358_k127_1323031_10	1410666.JHXG01000012_gene255	2.094e-09	70.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,2FM38@200643|Bacteroidia	976|Bacteroidetes	G	Kinase, PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158358_k127_1323031_11	394221.Mmar10_1665	0.0005415	48.0	COG1520@1|root,COG4447@1|root,COG1520@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2VEV5@28211|Alphaproteobacteria,43ZGC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158358_k127_1323031_1	469371.Tbis_2951	5.035e-100	333.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4DZTV@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158358_k127_1323031_8	240016.ABIZ01000001_gene3216	2.375e-15	81.0	COG0560@1|root,COG3187@1|root,COG0560@2|Bacteria,COG3187@2|Bacteria,46VDQ@74201|Verrucomicrobia,2ITM4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158358_k127_1323031_7	929712.KI912613_gene2019	1.973e-24	104.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	fdnI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158358_k127_1323124_2	1173020.Cha6605_6150	7.407e-09	57.0	COG5485@1|root,COG5485@2|Bacteria,1G6SP@1117|Cyanobacteria	1117|Cyanobacteria	S	Ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158358_k127_1323124_0	1458427.BAWN01000018_gene1140	6.425e-230	718.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria,4ACES@80864|Comamonadaceae	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158358_k127_1323124_1	390989.JOEG01000021_gene2650	4.596e-13	80.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158358_k127_1324116_3	1157635.KB892003_gene3679	5.431e-21	107.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158358_k127_1324116_4	1156844.KB891799_gene1238	1.687e-17	96.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158358_k127_1324116_0	644966.Tmar_0092	3.246e-65	238.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
SRR25158358_k127_1324116_1	469383.Cwoe_4636	2.722e-28	114.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CQSQ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158358_k127_1324116_2	1283299.AUKG01000002_gene3860	9.157e-24	104.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158358_k127_1325892_6	1122138.AQUZ01000046_gene323	5.077e-14	73.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4DQ29@85009|Propionibacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158358_k127_1325892_0	266117.Rxyl_1110	7.864e-176	565.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158358_k127_1325892_3	326424.FRAAL4823	2.169e-51	190.0	COG0586@1|root,COG0586@2|Bacteria,2GN4A@201174|Actinobacteria,4EWQF@85013|Frankiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158358_k127_1325892_4	570268.ANBB01000010_gene4970	1.074e-37	151.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_1325892_2	357808.RoseRS_4601	1.34e-51	198.0	COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi,375MR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158358_k127_1325892_1	1380390.JIAT01000009_gene661	4.826e-66	233.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria,4CTN8@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158358_k127_1325892_5	864069.MicloDRAFT_00003640	4.075e-27	116.0	COG2044@1|root,COG2044@2|Bacteria,1NI0Y@1224|Proteobacteria,2UJJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158358_k127_1331723_1	85643.Tmz1t_2631	1.014e-15	81.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KV4T@206389|Rhodocyclales	206389|Rhodocyclales	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
SRR25158358_k127_1331723_3	1177594.MIC448_860003	1.961e-09	68.0	2B2YE@1|root,31VJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1331723_2	1002340.AFCF01000011_gene2703	2.52e-11	67.0	COG2329@1|root,COG2329@2|Bacteria,1N1IT@1224|Proteobacteria,2UCHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158358_k127_1331723_4	345341.KUTG_04140	3.649e-08	63.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1331723_0	1048834.TC41_1472	3.804e-30	121.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,27845@186823|Alicyclobacillaceae	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158358_k127_1332072_3	1206101.AZXC01000013_gene949	2.441e-38	159.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158358_k127_1332072_4	439235.Dalk_3657	4.349e-29	128.0	COG1917@1|root,COG1917@2|Bacteria,1RHSW@1224|Proteobacteria,42TSH@68525|delta/epsilon subdivisions,2WQ63@28221|Deltaproteobacteria,2MKHC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1332072_0	1089544.KB912942_gene1307	8.473e-63	226.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4DXV2@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_1332072_2	525904.Tter_2213	4.845e-43	174.0	COG0726@1|root,COG0726@2|Bacteria,2NRJ2@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158358_k127_1332072_1	1123023.JIAI01000004_gene7970	3.917e-45	166.0	COG2309@1|root,COG2309@2|Bacteria,2I8N4@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase activity	nicX	-	1.13.11.9	ko:K18028	ko00760,ko01120,map00760,map01120	M00622	R09125	RC02430	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158358_k127_1334923_11	469383.Cwoe_3472	1.25e-20	96.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158358_k127_1334923_8	1068980.ARVW01000001_gene543	6.819e-56	211.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	CBM_6,F5_F8_type_C,GSDH,Glyco_hydro_99,PKD,ThuA
SRR25158358_k127_1334923_3	869210.Marky_0739	1.114e-114	379.0	COG0451@1|root,COG0451@2|Bacteria,1WMCY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158358_k127_1334923_1	1173020.Cha6605_5434	9.313e-158	509.0	COG4976@1|root,COG4976@2|Bacteria,1GQBZ@1117|Cyanobacteria	1117|Cyanobacteria	S	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158358_k127_1334923_4	373994.Riv7116_0370	1.879e-101	337.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria,1HIZY@1161|Nostocales	1117|Cyanobacteria	JM	TIGRFAM Glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR25158358_k127_1334923_6	1510531.JQJJ01000008_gene4002	1.511e-70	252.0	COG2120@1|root,COG2120@2|Bacteria,1MX2V@1224|Proteobacteria,2TT5F@28211|Alphaproteobacteria,3JVNZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158358_k127_1334923_9	1220534.B655_0998	4.583e-53	194.0	COG1898@1|root,arCOG04188@2157|Archaea,2XWJQ@28890|Euryarchaeota	28890|Euryarchaeota	M	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158358_k127_1334923_7	2002.JOEQ01000050_gene8377	3.949e-66	241.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4EG43@85012|Streptosporangiales	2|Bacteria	M	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784,ko:K20534	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase,Glycos_transf_2
SRR25158358_k127_1334923_2	66897.DJ64_14855	2.652e-144	475.0	COG4310@1|root,COG4310@2|Bacteria,2GK72@201174|Actinobacteria	201174|Actinobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47,Peptidase_M28
SRR25158358_k127_1334923_12	67267.JNXT01000003_gene4049	5.243e-05	51.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,2GMWU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	GO:0001666,GO:0006082,GO:0006355,GO:0006629,GO:0006631,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016999,GO:0017144,GO:0019219,GO:0019222,GO:0019541,GO:0019679,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0036293,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0046459,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07110,ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
SRR25158358_k127_1334923_0	469383.Cwoe_3494	2.777e-175	565.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158358_k127_1334923_5	1009370.ALO_14287	5.26e-71	246.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes	909932|Negativicutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158358_k127_1335281_1	1122611.KB903944_gene1134	4.557e-68	256.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158358_k127_1335281_2	1283299.AUKG01000002_gene3897	8.039e-51	203.0	COG1316@1|root,COG1316@2|Bacteria,2HPMP@201174|Actinobacteria,4CQZU@84995|Rubrobacteria	84995|Rubrobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158358_k127_1335281_0	477974.Daud_1184	6.629e-89	311.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,261NP@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158358_k127_1335281_3	1122947.FR7_1923	7.593e-29	119.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H2DW@909932|Negativicutes	909932|Negativicutes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158358_k127_1340340_12	1380390.JIAT01000009_gene840	8.485e-25	104.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4CQ49@84995|Rubrobacteria	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158358_k127_1340340_8	479433.Caci_0425	3.762e-89	302.0	COG0596@1|root,COG0596@2|Bacteria,2IFCI@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158358_k127_1340340_4	1173026.Glo7428_1707	9.529e-111	372.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4	ko:K00543,ko:K16130,ko:K18896,ko:K18897,ko:K21515	ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100	M00037	R03130,R04905,R10060,R10061	RC00003,RC00392,RC03038,RC03040	ko00000,ko00001,ko00002,ko01000,ko01008,ko03009	-	-	-	AMP-binding,Aminotran_1_2,AviRa,Condensation,Dimerisation2,Hen1_L,MTS,Methyltransf_12,Methyltransf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding
SRR25158358_k127_1340340_11	469383.Cwoe_5243	1.864e-37	150.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CQ60@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158358_k127_1340340_10	1137271.AZUM01000002_gene2480	2.319e-49	182.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4E0P0@85010|Pseudonocardiales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158358_k127_1340340_2	479434.Sthe_2121	4.821e-240	766.0	COG2609@1|root,COG2609@2|Bacteria,2G7U8@200795|Chloroflexi	200795|Chloroflexi	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158358_k127_1340340_5	196162.Noca_1177	2.681e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DWK9@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	idnO	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158358_k127_1340340_9	1380390.JIAT01000010_gene3356	3.735e-53	192.0	COG2080@1|root,COG2080@2|Bacteria,2H5UV@201174|Actinobacteria	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
SRR25158358_k127_1340340_0	1382306.JNIM01000001_gene3229	1.169e-302	949.0	COG1529@1|root,COG1529@2|Bacteria,2G7M5@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_1340340_7	1382306.JNIM01000001_gene3230	6.118e-94	314.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_1340340_6	1382306.JNIM01000001_gene3231	3.608e-98	332.0	COG0574@1|root,COG0574@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158358_k127_1340340_3	1382306.JNIM01000001_gene3232	1.587e-115	377.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158358_k127_1340340_1	1382306.JNIM01000001_gene3234	5.735e-269	838.0	COG3848@1|root,COG3848@2|Bacteria,2G8N4@200795|Chloroflexi	200795|Chloroflexi	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
SRR25158358_k127_1340340_14	469383.Cwoe_4106	8.15e-08	54.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4CT27@84995|Rubrobacteria	84995|Rubrobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158358_k127_1340368_2	298655.KI912266_gene2770	1.179e-49	181.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158358_k127_1340368_1	298655.KI912266_gene2771	1.306e-76	263.0	28KBH@1|root,2Z9YH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1340368_0	1267535.KB906767_gene2436	1.105e-221	698.0	COG0578@1|root,COG0578@2|Bacteria,3Y2YF@57723|Acidobacteria,2JI40@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158358_k127_1343518_4	555793.WSK_2157	8.307e-09	67.0	COG2244@1|root,COG2244@2|Bacteria,1R6H3@1224|Proteobacteria,2TUWJ@28211|Alphaproteobacteria,2KCB7@204457|Sphingomonadales	204457|Sphingomonadales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
SRR25158358_k127_1343518_1	1499967.BAYZ01000085_gene5179	5.108e-41	170.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_1343518_2	684949.ATTJ01000003_gene3184	2.894e-22	109.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_1343518_3	1120936.KB907210_gene5545	5.735e-15	87.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4EHVT@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_1343518_0	56110.Oscil6304_3545	1.152e-53	206.0	COG0438@1|root,COG0438@2|Bacteria,1G40J@1117|Cyanobacteria,1H9VA@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_1343518_5	1198452.Jab_1c18910	5.867e-07	62.0	COG1807@1|root,COG1807@2|Bacteria,1R4F0@1224|Proteobacteria,2VNW5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158358_k127_1346343_4	1125973.JNLC01000010_gene1858	9.641e-24	111.0	2E5W4@1|root,330K6@2|Bacteria,1N893@1224|Proteobacteria,2UGUZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRR25158358_k127_1346343_0	267608.RSc0028	4.725e-187	596.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1K02G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158358_k127_1346343_5	330084.JNYZ01000015_gene6064	1.597e-21	98.0	COG1917@1|root,COG1917@2|Bacteria,2HBEG@201174|Actinobacteria	201174|Actinobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1346343_3	1110697.NCAST_02_00430	1.028e-32	137.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4G1GA@85025|Nocardiaceae	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158358_k127_1346343_6	1394178.AWOO02000078_gene2031	1.592e-17	88.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4EJ1I@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158358_k127_1346343_1	1259795.ARJK01000002_gene272	1.374e-52	191.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,42G50@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM LemA family protein	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158358_k127_1346343_2	1234679.BN424_581	3.712e-34	139.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,27FNG@186828|Carnobacteriaceae	91061|Bacilli	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158358_k127_135022_2	991905.SL003B_2232	2.305e-40	155.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,4BPPV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158358_k127_135022_1	469383.Cwoe_5239	2.366e-81	279.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CQXI@84995|Rubrobacteria	84995|Rubrobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRR25158358_k127_135022_3	324057.Pjdr2_0444	7.036e-33	141.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,276F7@186822|Paenibacillaceae	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
SRR25158358_k127_135022_0	469383.Cwoe_5241	1.519e-253	801.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158358_k127_1366175_1	867903.ThesuDRAFT_00615	1.386e-102	349.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WCEJ@538999|Clostridiales incertae sedis	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158358_k127_1366175_3	469383.Cwoe_4528	5.436e-64	226.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CQ0V@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158358_k127_1366175_2	3067.XP_002951648.1	1.564e-91	313.0	COG0126@1|root,KOG1367@2759|Eukaryota,37RUX@33090|Viridiplantae,34GPY@3041|Chlorophyta	3041|Chlorophyta	G	Belongs to the phosphoglycerate kinase family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iRC1080.CRv4_Au5_s22_g9800_t1	PGK
SRR25158358_k127_1366175_0	351607.Acel_1114	8.111e-140	454.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4ES5V@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158358_k127_1366175_4	888060.HMPREF9081_0828	4.695e-29	125.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4H222@909932|Negativicutes	909932|Negativicutes	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158358_k127_1373480_0	1005395.CSV86_19203	2.893e-119	392.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,1RQK2@1236|Gammaproteobacteria,1YVGI@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158358_k127_1374379_8	1123258.AQXZ01000014_gene4818	5.599e-24	115.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4G23T@85025|Nocardiaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158358_k127_1374379_1	760568.Desku_0350	3.744e-102	341.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,2608G@186807|Peptococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
SRR25158358_k127_1374379_7	247490.KSU1_B0183	2.464e-29	123.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158358_k127_1374379_3	469383.Cwoe_5518	2.524e-60	213.0	COG1528@1|root,COG1528@2|Bacteria,2IG5S@201174|Actinobacteria,4CU3R@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferritin-like domain	-	-	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158358_k127_1374379_6	1121430.JMLG01000005_gene682	1.311e-33	139.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,2629H@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158358_k127_1374379_0	1283299.AUKG01000001_gene1484	3.424e-122	407.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CRR6@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158358_k127_1374379_5	700508.D174_26480	2.463e-40	157.0	COG4923@1|root,COG4923@2|Bacteria,2IJP8@201174|Actinobacteria,238UV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
SRR25158358_k127_1374379_4	1380390.JIAT01000009_gene1527	1.39e-59	212.0	COG1573@1|root,COG1573@2|Bacteria,2HNTA@201174|Actinobacteria,4CQ1J@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158358_k127_1374379_2	1283299.AUKG01000001_gene1474	8.456e-80	285.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158358_k127_1379380_0	469383.Cwoe_2633	5.187e-169	549.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158358_k127_1379380_2	1246474.ANBE01000050_gene1562	7.494e-35	142.0	COG1802@1|root,COG1802@2|Bacteria,2GMZ9@201174|Actinobacteria,4EIWE@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_1379380_1	1304876.AZVC01000002_gene647	3.699e-53	201.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1385899_2	1189612.A33Q_2746	4.236e-08	59.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158358_k127_1385899_0	243090.RB13224	3.596e-164	530.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158358_k127_1385899_1	42256.RradSPS_1152	8.589e-33	132.0	2B5Y2@1|root,31YU2@2|Bacteria,2H193@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1388169_5	1283299.AUKG01000001_gene1753	2.409e-08	61.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria,4CQ1U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1388169_4	747365.Thena_0216	1.022e-14	80.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,42GP3@68295|Thermoanaerobacterales	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158358_k127_1388169_2	469383.Cwoe_0007	3.795e-49	182.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CQBX@84995|Rubrobacteria	84995|Rubrobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158358_k127_1388169_3	1278073.MYSTI_04725	1.754e-38	155.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158358_k127_1388169_1	314254.OA2633_08339	1.314e-100	337.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,43W93@69657|Hyphomonadaceae	28211|Alphaproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158358_k127_1388169_0	469383.Cwoe_3191	7.847e-111	367.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4CPCC@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158358_k127_1391616_8	1283299.AUKG01000003_gene234	2.163e-15	86.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4CR35@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_1391616_3	1169161.KB897730_gene1080	4.873e-150	487.0	COG2141@1|root,COG2141@2|Bacteria,2GJ04@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158358_k127_1391616_7	397278.JOJN01000007_gene3443	6.045e-22	111.0	28RGR@1|root,2ZDVS@2|Bacteria,2GR2V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1391616_0	1394178.AWOO02000001_gene1496	5.086e-240	750.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4EFSX@85012|Streptosporangiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102,ko:K11472	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158358_k127_1391616_1	1394178.AWOO02000001_gene1495	2.706e-190	603.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4EH4E@85012|Streptosporangiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
SRR25158358_k127_1391616_6	479434.Sthe_0515	8.18e-49	188.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi,27YBG@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158358_k127_1391616_4	1123023.JIAI01000007_gene1954	3.397e-70	246.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158358_k127_1391616_2	247634.GPB2148_3618	2.397e-152	493.0	COG0665@1|root,COG0665@2|Bacteria,1R40G@1224|Proteobacteria,1SME5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158358_k127_1391616_9	644966.Tmar_1582	1.717e-09	69.0	COG4447@1|root,COG4447@2|Bacteria,1TRJ4@1239|Firmicutes,25BU3@186801|Clostridia	186801|Clostridia	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158358_k127_1391616_5	1121479.AUBS01000001_gene3028	2.551e-63	225.0	COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,2TR55@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0004 Ammonia permease	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
SRR25158358_k127_1404835_6	1380390.JIAT01000002_gene5962	2.902e-25	115.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPDT@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.19	ko:K00137	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R02549	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158358_k127_1404835_0	469383.Cwoe_3295	9.305e-197	619.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158358_k127_1404835_7	1122939.ATUD01000001_gene333	2.518e-21	101.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158358_k127_1404835_1	1122939.ATUD01000001_gene334	7.953e-154	496.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158358_k127_1404835_5	298653.Franean1_1623	7.366e-39	150.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria	201174|Actinobacteria	IQ	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158358_k127_1404835_2	479434.Sthe_0863	5.615e-126	426.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,27Z0R@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158358_k127_1404835_4	1236976.JCM16418_4793	4.735e-56	218.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,26QFZ@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158358_k127_1404835_3	469383.Cwoe_1859	7.644e-104	348.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4CPRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Glucose inhibited division protein A	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158358_k127_1409090_1	1206101.AZXC01000007_gene2590	3.576e-84	287.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158358_k127_1409090_0	1278078.G419_15262	1.716e-191	617.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4FUE4@85025|Nocardiaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158358_k127_1420286_0	479431.Namu_4824	1.086e-111	385.0	COG0438@1|root,COG1413@1|root,COG0438@2|Bacteria,COG1413@2|Bacteria,2HMNV@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2
SRR25158358_k127_1420286_2	1123052.AUDF01000013_gene937	1.269e-92	327.0	COG1819@1|root,COG1819@2|Bacteria,2HEKU@201174|Actinobacteria,4FM1Y@85023|Microbacteriaceae	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR25158358_k127_1420286_1	1312954.KI914880_gene1322	3.074e-95	329.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158358_k127_1420286_3	31964.CMS0818	9.38e-48	184.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4FNS0@85023|Microbacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158358_k127_1420286_4	1380390.JIAT01000014_gene6036	3.405e-26	113.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4CSB0@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_1430846_0	469383.Cwoe_2838	1.156e-259	811.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CP62@84995|Rubrobacteria	84995|Rubrobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158358_k127_1430846_1	1121933.AUHH01000015_gene431	4.125e-39	165.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DN32@85009|Propionibacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158358_k127_1433230_2	211114.JOEF01000005_gene2291	4.963e-05	53.0	28KIP@1|root,2ZA3U@2|Bacteria,2I3VC@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158358_k127_1433230_0	2074.JNYD01000003_gene3704	3.147e-41	163.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158358_k127_1433230_1	1445613.JALM01000009_gene728	4.838e-18	97.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4E4IM@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158358_k127_1438888_1	1380390.JIAT01000010_gene4084	3.065e-31	137.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CSJV@84995|Rubrobacteria	84995|Rubrobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HD
SRR25158358_k127_1438888_0	1380390.JIAT01000011_gene2566	7.728e-202	642.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CP97@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158358_k127_144047_7	1089550.ATTH01000002_gene48	2.71e-28	121.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,1FK71@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158358_k127_144047_9	1173025.GEI7407_1817	8.143e-09	64.0	COG2510@1|root,COG2510@2|Bacteria,1GACA@1117|Cyanobacteria,1HGEI@1150|Oscillatoriales	1117|Cyanobacteria	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
SRR25158358_k127_144047_5	1123023.JIAI01000003_gene2825	1.058e-93	316.0	COG0449@1|root,COG0449@2|Bacteria,2IIQ7@201174|Actinobacteria	201174|Actinobacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158358_k127_144047_2	1121430.JMLG01000007_gene2560	1.329e-123	409.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,2611N@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iHN637.CLJU_RS10045	Aminotran_3
SRR25158358_k127_144047_6	309801.trd_A0768	2.101e-66	239.0	COG1540@1|root,COG1540@2|Bacteria,2G8DT@200795|Chloroflexi,27YX7@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158358_k127_144047_1	266117.Rxyl_2464	7.733e-150	486.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4CP7I@84995|Rubrobacteria	84995|Rubrobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158358_k127_144047_4	1050202.KB913024_gene1935	1.788e-108	359.0	COG2049@1|root,COG2049@2|Bacteria,2I9QZ@201174|Actinobacteria,409UY@622450|Actinopolysporales	201174|Actinobacteria	E	Pfam:AHS1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_C_D
SRR25158358_k127_144047_3	42256.RradSPS_0920	1.115e-119	392.0	COG1984@1|root,COG1984@2|Bacteria,2GITH@201174|Actinobacteria,4CREH@84995|Rubrobacteria	84995|Rubrobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
SRR25158358_k127_144047_8	649747.HMPREF0083_00420	3.411e-24	110.0	COG0511@1|root,COG0511@2|Bacteria,1VGJG@1239|Firmicutes,4HQEA@91061|Bacilli,2734J@186822|Paenibacillaceae	91061|Bacilli	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158358_k127_144047_0	479434.Sthe_2811	4.562e-178	574.0	COG1529@1|root,COG1529@2|Bacteria,2G608@200795|Chloroflexi,27YZY@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_1444852_1	765698.Mesci_6403	4.413e-132	436.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158358_k127_1444852_0	1380390.JIAT01000009_gene1538	4.054e-142	461.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158358_k127_1444852_3	525904.Tter_1996	2.898e-48	182.0	COG2186@1|root,COG2186@2|Bacteria,2NRIT@2323|unclassified Bacteria	2|Bacteria	K	FadR C-terminal domain	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158358_k127_1444852_4	243090.RB3774	6.877e-25	116.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158358_k127_1444852_2	1380390.JIAT01000010_gene4431	1.759e-59	216.0	COG3629@1|root,COG3629@2|Bacteria,2GKKQ@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158358_k127_1450299_0	1329516.JPST01000014_gene628	2.503e-127	419.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,27BH0@186824|Thermoactinomycetaceae	91061|Bacilli	L	Bacterial dnaA protein helix-turn-helix domain	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158358_k127_1450299_12	1121940.AUDZ01000013_gene638	7.223e-09	59.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1XMQA@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158358_k127_1450299_9	1380390.JIAT01000009_gene1793	6.367e-20	93.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4CQCA@84995|Rubrobacteria	84995|Rubrobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158358_k127_1450299_10	1122939.ATUD01000013_gene890	2.46e-19	94.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4CQSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158358_k127_1450299_6	1380390.JIAT01000009_gene1795	8.649e-52	194.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CPXT@84995|Rubrobacteria	84995|Rubrobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158358_k127_1450299_7	1121423.JONT01000003_gene1131	2.303e-33	147.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158358_k127_1450299_8	1380390.JIAT01000009_gene1798	6.505e-25	111.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CQFC@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158358_k127_1450299_3	929712.KI912613_gene1113	5.315e-77	265.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CQ24@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158358_k127_1450299_5	1125863.JAFN01000001_gene2682	1.493e-58	216.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158358_k127_1450299_4	469383.Cwoe_5941	2.067e-62	220.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158358_k127_1450299_13	1121920.AUAU01000005_gene1012	9.396e-08	63.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04092,ko:K04093,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRR25158358_k127_1450299_11	570952.ATVH01000011_gene138	1.227e-10	76.0	COG1266@1|root,COG1266@2|Bacteria,1NF98@1224|Proteobacteria,2UHG6@28211|Alphaproteobacteria,2JUK0@204441|Rhodospirillales	204441|Rhodospirillales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158358_k127_1450299_1	251229.Chro_2995	1.275e-106	374.0	COG0744@1|root,COG0744@2|Bacteria,1G1XF@1117|Cyanobacteria,3VIDV@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Penicillin binding protein transpeptidase domain	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158358_k127_1450299_2	469383.Cwoe_4686	3.984e-81	284.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CQ5A@84995|Rubrobacteria	84995|Rubrobacteria	H	molybdopterin binding domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158358_k127_1451699_6	1120983.KB894570_gene1859	9.637e-45	174.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158358_k127_1451699_13	1313172.YM304_16310	4.429e-16	87.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,Lipase_GDSL_2,PT-HINT,RHS_repeat,Ricin_B_lectin
SRR25158358_k127_1451699_2	981369.JQMJ01000003_gene7549	5.234e-87	297.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,2NEYY@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_1451699_12	1214101.BN159_4593	1.91e-16	93.0	COG1277@1|root,COG1277@2|Bacteria,2GKKP@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158358_k127_1451699_1	1313172.YM304_41490	3.962e-90	322.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_1451699_9	1313172.YM304_41480	7.691e-31	133.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158358_k127_1451699_3	1996.JOFO01000008_gene3069	6.125e-75	266.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4EN0R@85012|Streptosporangiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158358_k127_1451699_11	42256.RradSPS_0736	1.561e-17	87.0	COG0360@1|root,COG0360@2|Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158358_k127_1451699_5	469383.Cwoe_5911	8.976e-49	177.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158358_k127_1451699_10	1283299.AUKG01000001_gene1817	5.035e-24	103.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CQW6@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158358_k127_1451699_8	266117.Rxyl_0851	1.576e-32	136.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158358_k127_1451699_0	635013.TherJR_2972	2.781e-142	465.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158358_k127_1451699_7	313596.RB2501_12217	1.443e-42	169.0	COG0346@1|root,COG0346@2|Bacteria,4P85Q@976|Bacteroidetes	976|Bacteroidetes	C	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_1451699_4	469383.Cwoe_5915	1.41e-62	220.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CPAP@84995|Rubrobacteria	84995|Rubrobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158358_k127_1456122_0	1192034.CAP_6601	1.808e-298	951.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158358_k127_1460391_2	861299.J421_0867	5.681e-31	135.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_0867|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158358_k127_1460391_0	218284.CCDN010000006_gene3550	5.374e-136	445.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZDD3@1386|Bacillus	91061|Bacilli	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158358_k127_1460391_1	1089550.ATTH01000001_gene1192	1.783e-85	290.0	COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,1FJQX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158358_k127_1465800_6	266117.Rxyl_0544	1.042e-74	261.0	COG1012@1|root,COG1012@2|Bacteria,2GMNB@201174|Actinobacteria,4CPME@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM aldehyde dehydrogenase	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158358_k127_1465800_7	469383.Cwoe_5081	3.043e-72	254.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CT7G@84995|Rubrobacteria	84995|Rubrobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_1465800_0	1158050.KB895476_gene2688	8.385e-181	572.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,1W7QX@1268|Micrococcaceae	201174|Actinobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158358_k127_1465800_1	1151119.KB895504_gene1286	1.014e-144	464.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158358_k127_1465800_2	469383.Cwoe_5082	1.177e-118	399.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CTBJ@84995|Rubrobacteria	84995|Rubrobacteria	C	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1465800_4	257310.BB4687	7.573e-108	364.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2VK18@28216|Betaproteobacteria,3T3W8@506|Alcaligenaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_1465800_5	269799.Gmet_1046	1.124e-76	271.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria,43TBJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158358_k127_1465800_8	266117.Rxyl_0527	7.331e-54	198.0	COG2186@1|root,COG2186@2|Bacteria,2GRNU@201174|Actinobacteria	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_1465800_3	754035.Mesau_03276	9.475e-112	382.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2U3FT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
SRR25158358_k127_1465800_9	1040986.ATYO01000010_gene3048	0.0001125	48.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2U1YY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158358_k127_1466786_9	314285.KT71_01600	4.038e-06	52.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RU1Y@1236|Gammaproteobacteria,1J7UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158358_k127_1466786_7	1869.MB27_34950	3.902e-32	136.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1466786_5	1394178.AWOO02000089_gene1096	3.784e-46	177.0	COG0596@1|root,COG0596@2|Bacteria,2I8EU@201174|Actinobacteria,4EQPH@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	lipV	GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575	-	ko:K19311	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158358_k127_1466786_2	929712.KI912613_gene4577	1.299e-95	329.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4CQBQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1466786_8	530564.Psta_0072	3.633e-22	109.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1466786_1	42256.RradSPS_2933	1.562e-137	441.0	COG5564@1|root,COG5564@2|Bacteria,2GMW9@201174|Actinobacteria,4CSEH@84995|Rubrobacteria	84995|Rubrobacteria	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
SRR25158358_k127_1466786_0	42256.RradSPS_2932	2.158e-160	514.0	COG5441@1|root,COG5441@2|Bacteria,2GKDK@201174|Actinobacteria,4CRV9@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
SRR25158358_k127_1466786_6	1239962.C943_03877	2.043e-40	161.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158358_k127_1466786_3	309801.trd_A0080	1.546e-82	283.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158358_k127_1466786_4	1380390.JIAT01000010_gene3347	8.668e-81	277.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CSXI@84995|Rubrobacteria	84995|Rubrobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158358_k127_146901_2	1449346.JQMO01000003_gene2379	3.252e-26	113.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,2M33U@2063|Kitasatospora	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158358_k127_146901_1	471853.Bcav_1854	7.463e-37	153.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158358_k127_146901_0	211165.AJLN01000125_gene5480	1.786e-131	439.0	COG0659@1|root,COG0659@2|Bacteria,1G0NU@1117|Cyanobacteria,1JJ5V@1189|Stigonemataceae	1117|Cyanobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158358_k127_146901_3	981384.AEYW01000001_gene1490	1.629e-11	70.0	COG1234@1|root,COG1234@2|Bacteria,1RIJP@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_4
SRR25158358_k127_1470867_5	1122135.KB893138_gene1151	2.092e-13	72.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TTJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	phnY	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158358_k127_1470867_4	1283299.AUKG01000001_gene1437	1.154e-20	97.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CPBJ@84995|Rubrobacteria	84995|Rubrobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158358_k127_1470867_0	1341151.ASZU01000001_gene675	5.419e-146	475.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,27BMB@186824|Thermoactinomycetaceae	91061|Bacilli	F	Adenylosuccinate lyase C-terminus	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09895	ADSL_C,Lyase_1
SRR25158358_k127_1470867_1	999423.HMPREF9161_00409	6.024e-115	384.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158358_k127_1470867_2	1380390.JIAT01000013_gene310	1.793e-62	224.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158358_k127_1470867_3	1120945.ATUW01000001_gene1552	2e-60	213.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4D3M5@85005|Actinomycetales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158358_k127_1471024_4	929712.KI912613_gene4586	3.822e-07	57.0	29Z0D@1|root,30KXH@2|Bacteria,2HP8W@201174|Actinobacteria,4CQM4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1471024_5	1283299.AUKG01000001_gene3177	2.687e-05	54.0	2A2FM@1|root,30QSR@2|Bacteria,2HRCN@201174|Actinobacteria,4CTA4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1471024_2	469383.Cwoe_1858	3.098e-27	120.0	2B6US@1|root,31ZU9@2|Bacteria,2HRE3@201174|Actinobacteria,4CTC7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1471024_0	469383.Cwoe_5785	7.78e-126	434.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158358_k127_1471024_1	1254432.SCE1572_08780	1.362e-30	129.0	COG0642@1|root,COG2205@2|Bacteria,1N5YU@1224|Proteobacteria,42N55@68525|delta/epsilon subdivisions,2WVAY@28221|Deltaproteobacteria,2YWI6@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158358_k127_1471024_3	1313172.YM304_19130	1.044e-11	67.0	COG1600@1|root,COG1600@2|Bacteria,2HGVB@201174|Actinobacteria,4CNW5@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Fer4_16
SRR25158358_k127_1471125_7	1122939.ATUD01000005_gene2721	7.976e-25	114.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CPY4@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_N
SRR25158358_k127_1471125_2	469383.Cwoe_3224	5.211e-82	284.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158358_k127_1471125_6	469383.Cwoe_3223	2.823e-27	114.0	COG0858@1|root,COG0858@2|Bacteria,2HPFC@201174|Actinobacteria,4CQTS@84995|Rubrobacteria	84995|Rubrobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158358_k127_1471125_8	644966.Tmar_1020	3.41e-12	79.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158358_k127_1471125_0	1122939.ATUD01000005_gene2718	2.927e-193	622.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158358_k127_1471125_10	477641.MODMU_4378	1.641e-07	64.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria	201174|Actinobacteria	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158358_k127_1471125_1	469383.Cwoe_3219	1.35e-157	510.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158358_k127_1471125_9	227377.CBU_1434	5.534e-11	73.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1JEBZ@118969|Legionellales	118969|Legionellales	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158358_k127_1471125_3	1206737.BAGF01000058_gene3839	3.682e-40	153.0	COG0346@1|root,COG0346@2|Bacteria,2IKKR@201174|Actinobacteria,4G25N@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_1471125_4	1380390.JIAT01000009_gene943	8.517e-37	147.0	COG0607@1|root,COG0607@2|Bacteria,2IKTC@201174|Actinobacteria,4CQJC@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158358_k127_1471125_5	469383.Cwoe_1673	2.777e-34	136.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CPFJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158358_k127_1472593_0	1123023.JIAI01000020_gene2094	4.426e-80	280.0	COG0387@1|root,COG0387@2|Bacteria,2IA57@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium calcium exchanger	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158358_k127_1472593_1	63400.XP_003009905.1	3.226e-66	235.0	COG2008@1|root,KOG1368@2759|Eukaryota,38EQY@33154|Opisthokonta,3NWDM@4751|Fungi,3QJEJ@4890|Ascomycota,20EI0@147545|Eurotiomycetes,3B2XC@33183|Onygenales,3FX2Q@34384|Arthrodermataceae	4751|Fungi	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158358_k127_1480555_5	1146883.BLASA_3642	4.301e-06	56.0	COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria,4ESRY@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	bcsA	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,PilZ
SRR25158358_k127_1480555_3	1157637.KB892124_gene594	2.431e-10	68.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158358_k127_1480555_2	472759.Nhal_2917	2.704e-32	128.0	arCOG11477@1|root,32TJG@2|Bacteria,1MYXX@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158358_k127_1480555_0	357808.RoseRS_1085	9.975e-140	451.0	COG1082@1|root,COG1082@2|Bacteria,2G6W6@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158358_k127_1480555_1	1380390.JIAT01000013_gene249	2.245e-61	231.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158358_k127_1480555_4	1122612.AUBA01000004_gene497	4.02e-07	61.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1484385_4	1380390.JIAT01000010_gene4158	7.588e-33	131.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CP8Z@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158358_k127_1484385_0	891968.Anamo_1900	4.322e-179	579.0	COG1003@1|root,COG1003@2|Bacteria,3TAJQ@508458|Synergistetes	508458|Synergistetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158358_k127_1484385_3	1122939.ATUD01000014_gene1105	1.615e-56	202.0	COG3576@1|root,COG3576@2|Bacteria,2GKCF@201174|Actinobacteria,4CT0M@84995|Rubrobacteria	84995|Rubrobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158358_k127_1484385_1	469383.Cwoe_3745	1.905e-137	445.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CQ1M@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158358_k127_1484385_6	1146883.BLASA_2869	3.299e-16	79.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1484385_7	1232410.KI421412_gene337	6.385e-10	63.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158358_k127_1484385_2	1449346.JQMO01000003_gene2251	1.269e-90	303.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158358_k127_1484385_5	644283.Micau_4511	9.917e-20	90.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4DAY8@85008|Micromonosporales	201174|Actinobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158358_k127_1486026_2	1123023.JIAI01000007_gene1968	9.554e-111	366.0	COG0034@1|root,COG0034@2|Bacteria,2I3P1@201174|Actinobacteria	201174|Actinobacteria	F	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6
SRR25158358_k127_1486026_0	1123023.JIAI01000007_gene1967	7.262e-243	757.0	COG0174@1|root,COG0174@2|Bacteria,2I8RB@201174|Actinobacteria	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158358_k127_1486026_13	665956.HMPREF1032_02083	7.733e-24	106.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3WIJW@541000|Ruminococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158358_k127_1486026_7	443254.Marpi_1954	7.553e-53	196.0	COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158358_k127_1486026_14	266117.Rxyl_0939	2.743e-07	63.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158358_k127_1486026_12	479434.Sthe_3345	3.493e-34	138.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YF3@189775|Thermomicrobia	189775|Thermomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_1486026_4	1283299.AUKG01000002_gene4954	7.413e-84	282.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,4CQ25@84995|Rubrobacteria	84995|Rubrobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158358_k127_1486026_5	1379698.RBG1_1C00001G0299	6.181e-75	259.0	COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria	2|Bacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	LysM,Sod_Fe_C,Sod_Fe_N
SRR25158358_k127_1486026_11	861299.J421_3236	1.485e-40	157.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158358_k127_1486026_3	469383.Cwoe_5367	8.49e-95	326.0	COG1469@1|root,COG1469@2|Bacteria,2IBX9@201174|Actinobacteria	201174|Actinobacteria	S	Type I GTP cyclohydrolase folE2	-	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
SRR25158358_k127_1486026_8	1298863.AUEP01000011_gene623	1.18e-51	185.0	COG2030@1|root,COG2030@2|Bacteria,2IK2Z@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158358_k127_1486026_10	1380390.JIAT01000009_gene1194	1.227e-49	192.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4CPDC@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158358_k127_1486026_1	1380390.JIAT01000013_gene37	9.252e-152	488.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_1486026_9	861299.J421_4186	5.848e-50	185.0	COG0580@1|root,COG0580@2|Bacteria,1ZV9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158358_k127_1486026_6	1283299.AUKG01000003_gene505	2.103e-60	214.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CPEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158358_k127_1486917_2	1417296.U879_03495	3.242e-36	140.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,GFO_IDH_MocA
SRR25158358_k127_1486917_3	1333998.M2A_2672	1.622e-27	123.0	COG2227@1|root,COG2227@2|Bacteria,1NKIZ@1224|Proteobacteria,2UKY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158358_k127_1486917_1	1333998.M2A_1571	3.957e-49	186.0	COG0500@1|root,COG2226@2|Bacteria,1QWJE@1224|Proteobacteria,2U37M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158358_k127_1486917_0	1333998.M2A_2668	1.615e-157	511.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,2TVDH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
SRR25158358_k127_148751_0	1340493.JNIF01000003_gene1338	2.138e-43	169.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158358_k127_148751_1	234267.Acid_4094	5.414e-41	171.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158358_k127_148751_3	1123277.KB893172_gene533	1.434e-23	111.0	COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,47M5K@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
SRR25158358_k127_148751_2	313606.M23134_03302	4.531e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_1497570_1	477641.MODMU_3897	6.021e-09	65.0	COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria,4EURS@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158358_k127_1497570_0	768706.Desor_3194	9.864e-26	118.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,261N2@186807|Peptococcaceae	186801|Clostridia	M	PFAM Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158358_k127_1498000_0	469383.Cwoe_5122	2.966e-61	228.0	2DSF1@1|root,33FW6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1498000_1	90814.KL370891_gene682	7.979e-45	178.0	COG0458@1|root,COG0458@2|Bacteria,1RFH4@1224|Proteobacteria,1S5TJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EF	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158358_k127_1498000_2	694430.Natoc_0439	7.782e-14	82.0	COG0726@1|root,arCOG04934@2157|Archaea,2XX15@28890|Euryarchaeota,23VFF@183963|Halobacteria	183963|Halobacteria	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1500544_3	1463917.JODC01000003_gene5529	5.747e-09	65.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria	201174|Actinobacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158358_k127_1500544_0	1267535.KB906767_gene4149	1.505e-41	158.0	COG3685@1|root,COG3685@2|Bacteria	2|Bacteria	S	cellular response to DNA damage stimulus	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158358_k127_1500544_1	1449351.RISW2_12395	1.201e-27	125.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4KNVF@93682|Roseivivax	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158358_k127_1500544_2	1206726.BAFV01000123_gene6240	3.308e-15	80.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria,4G1KF@85025|Nocardiaceae	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158358_k127_1502840_22	324602.Caur_1591	3.483e-33	146.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158358_k127_1502840_14	1206101.AZXC01000010_gene211	5.015e-53	206.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158358_k127_1502840_28	1009370.ALO_08805	2.513e-18	94.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4H55G@909932|Negativicutes	909932|Negativicutes	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158358_k127_1502840_7	1283299.AUKG01000001_gene3201	3.133e-86	302.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158358_k127_1502840_3	1295642.H839_09323	9.353e-104	347.0	COG1235@1|root,COG1235@2|Bacteria,1U5T1@1239|Firmicutes,4I67K@91061|Bacilli,1WHQA@129337|Geobacillus	91061|Bacilli	S	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1502840_10	443255.SCLAV_3445	5.835e-71	252.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158358_k127_1502840_27	1123023.JIAI01000011_gene8939	2.128e-23	108.0	COG0500@1|root,COG2226@2|Bacteria,2INQ9@201174|Actinobacteria,4EEK7@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158358_k127_1502840_24	469383.Cwoe_4168	1.097e-30	140.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_1502840_20	469383.Cwoe_4168	2.923e-39	156.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_1502840_6	497321.C664_01720	5.474e-90	304.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VJ0T@28216|Betaproteobacteria,2KVJU@206389|Rhodocyclales	206389|Rhodocyclales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158358_k127_1502840_8	1382306.JNIM01000001_gene4148	1.383e-84	287.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi	200795|Chloroflexi	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_1502840_18	479434.Sthe_1008	3.716e-41	166.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158358_k127_1502840_11	1122917.KB899673_gene718	5.827e-61	218.0	COG2120@1|root,COG2120@2|Bacteria,1TUFR@1239|Firmicutes,4I855@91061|Bacilli,26YXG@186822|Paenibacillaceae	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158358_k127_1502840_4	1089551.KE386572_gene975	2.007e-94	322.0	COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2TRKZ@28211|Alphaproteobacteria,4BR7S@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158358_k127_1502840_9	1535287.JP74_10990	4.216e-79	274.0	COG0600@1|root,COG0600@2|Bacteria,1R3V5@1224|Proteobacteria,2TSG0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158358_k127_1502840_12	1122132.AQYH01000003_gene3187	4.695e-60	233.0	COG0715@1|root,COG0715@2|Bacteria,1NYKG@1224|Proteobacteria,2TTTW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158358_k127_1502840_16	1499967.BAYZ01000138_gene182	3.999e-50	188.0	COG1082@1|root,COG1082@2|Bacteria,2NRU1@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158358_k127_1502840_13	795797.C497_06414	3.638e-58	213.0	COG1402@1|root,arCOG04536@2157|Archaea,2XTQE@28890|Euryarchaeota,23V30@183963|Halobacteria	183963|Halobacteria	H	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158358_k127_1502840_17	880070.Cycma_1176	3.957e-49	186.0	COG2267@1|root,COG2267@2|Bacteria,4PN9Y@976|Bacteroidetes,47NPH@768503|Cytophagia	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158358_k127_1502840_15	1499967.BAYZ01000138_gene181	1.395e-52	207.0	COG0673@1|root,COG0673@2|Bacteria,2NR8T@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158358_k127_1502840_2	366394.Smed_0346	3.159e-129	427.0	COG0624@1|root,COG0624@2|Bacteria,1MW2W@1224|Proteobacteria,2U0TZ@28211|Alphaproteobacteria,4BBR8@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158358_k127_1502840_1	479434.Sthe_1095	1.46e-152	500.0	COG0028@1|root,COG0028@2|Bacteria,2GBV7@200795|Chloroflexi,27XIE@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158358_k127_1502840_31	443255.SCLAV_5128	0.0009013	48.0	COG1082@1|root,COG1082@2|Bacteria,2GK34@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	AP_endonuc_2
SRR25158358_k127_1502840_26	156978.CIMIT_09915	1.983e-28	119.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,22NV0@1653|Corynebacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158358_k127_1502840_0	469383.Cwoe_0469	1.584e-269	848.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158358_k127_1502840_29	1245475.ANAE01000078_gene5093	3.463e-16	79.0	COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4EKNK@85012|Streptosporangiales	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
SRR25158358_k127_1502840_23	1223543.GP2_033_00310	7.299e-33	137.0	COG0251@1|root,COG5637@1|root,COG0251@2|Bacteria,COG5637@2|Bacteria,2IN7X@201174|Actinobacteria,4GEKW@85026|Gordoniaceae	201174|Actinobacteria	J	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158358_k127_1502840_21	1996.JOFO01000020_gene2379	2.041e-34	140.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4EJGT@85012|Streptosporangiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158358_k127_1502840_5	1206730.BAGA01000058_gene2571	2.146e-91	310.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria,4FV8Y@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158358_k127_1502840_19	1896.JOAU01000019_gene2414	5.068e-40	159.0	COG0596@1|root,COG0596@2|Bacteria,2IJXZ@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158358_k127_1502840_30	6326.BUX.s00351.22	2.415e-14	78.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3BBF2@33208|Metazoa,3CS4Z@33213|Bilateria,40BUK@6231|Nematoda,1KUFP@119089|Chromadorea	33208|Metazoa	T	Cyclic nucleotide-monophosphate binding domain	PRKAR1A	GO:0000003,GO:0000166,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0010721,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030551,GO:0030552,GO:0030554,GO:0030951,GO:0030952,GO:0031032,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRR25158358_k127_150775_4	479435.Kfla_0417	5.376e-12	66.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158358_k127_150775_0	1123024.AUII01000025_gene2106	1.027e-146	471.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJD@85010|Pseudonocardiales	201174|Actinobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	drrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158358_k127_150775_1	1123024.AUII01000025_gene2107	9.251e-110	363.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4DZZ1@85010|Pseudonocardiales	201174|Actinobacteria	V	Transport permease protein	drrB	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158358_k127_150775_2	1449044.JMLE01000006_gene1140	7.867e-34	139.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
SRR25158358_k127_150775_5	211114.JOEF01000023_gene5697	8.016e-11	66.0	2C4DQ@1|root,335C3@2|Bacteria,2I5FZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_150775_3	526225.Gobs_1394	1.245e-17	85.0	2DP8X@1|root,33127@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1508003_2	1122247.C731_3271	1.198e-88	305.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,2339D@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA6_3	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158358_k127_1508003_0	1380393.JHVP01000003_gene1268	3.336e-174	563.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158358_k127_1508003_1	471852.Tcur_0327	7.913e-116	399.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EHQQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158358_k127_1511616_2	469383.Cwoe_3183	5.413e-74	262.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158358_k127_1511616_3	42256.RradSPS_1330	1.729e-07	57.0	COG3937@1|root,COG3937@2|Bacteria	2|Bacteria	-	-	phaI	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR25158358_k127_1511616_1	247490.KSU1_D0331	1.928e-105	363.0	COG0661@1|root,COG0661@2|Bacteria,2IXG0@203682|Planctomycetes	203682|Planctomycetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
SRR25158358_k127_1511616_0	570952.ATVH01000003_gene696	1.155e-313	974.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,2JQA5@204441|Rhodospirillales	204441|Rhodospirillales	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158358_k127_1513493_0	1206737.BAGF01000151_gene6270	9.564e-120	394.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4FYN0@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158358_k127_1513493_5	713586.KB900536_gene328	2.269e-20	98.0	COG2133@1|root,COG2133@2|Bacteria,1QWB2@1224|Proteobacteria	1224|Proteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158358_k127_1513493_6	344747.PM8797T_08964	2.126e-19	100.0	COG3021@1|root,COG3021@2|Bacteria,2J2SY@203682|Planctomycetes	203682|Planctomycetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158358_k127_1513493_1	42256.RradSPS_0787	8.144e-86	308.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CPAI@84995|Rubrobacteria	84995|Rubrobacteria	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158358_k127_1513493_7	700508.D174_08605	5.184e-09	63.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,239FS@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158358_k127_1513493_3	926560.KE387025_gene3982	9.913e-69	241.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_1513493_4	565033.GACE_2081	9.053e-43	173.0	COG0577@1|root,arCOG02312@2157|Archaea	2157|Archaea	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158358_k127_1513493_2	105422.BBPM01000047_gene1737	1.612e-70	246.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,2NIHT@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158358_k127_1515948_5	1206731.BAGB01000170_gene4570	2.042e-08	65.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4FWMS@85025|Nocardiaceae	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158358_k127_1515948_1	235985.BBPN01000012_gene6979	2.162e-66	245.0	COG3227@1|root,COG4409@1|root,COG3227@2|Bacteria,COG4409@2|Bacteria,2GN94@201174|Actinobacteria,2NEQG@228398|Streptacidiphilus	201174|Actinobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158358_k127_1515948_4	1200792.AKYF01000009_gene3107	2.094e-09	66.0	COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HM2Z@91061|Bacilli,26Y6V@186822|Paenibacillaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158358_k127_1515948_2	1380390.JIAT01000001_gene4997	2.042e-39	162.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158358_k127_1515948_0	469383.Cwoe_4495	6.159e-119	391.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CP9Q@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158358_k127_1515948_3	1397693.KK211187_gene2270	5.704e-15	75.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3WFKF@539002|Bacillales incertae sedis	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158358_k127_1523964_0	502025.Hoch_0257	1.336e-138	454.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158358_k127_1523964_2	1122939.ATUD01000005_gene2642	5.89e-16	84.0	COG0781@1|root,COG0781@2|Bacteria,2HP01@201174|Actinobacteria,4CQ9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158358_k127_1523964_1	1122939.ATUD01000005_gene2644	2.105e-59	217.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158358_k127_1524871_19	1283299.AUKG01000001_gene1628	9.435e-13	78.0	COG2304@1|root,COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
SRR25158358_k127_1524871_18	469383.Cwoe_5297	2.231e-14	86.0	COG3307@1|root,COG3307@2|Bacteria,2HREZ@201174|Actinobacteria,4CTDF@84995|Rubrobacteria	84995|Rubrobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158358_k127_1524871_5	929712.KI912613_gene4214	1.59e-58	207.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1524871_6	469383.Cwoe_3699	4.465e-57	203.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158358_k127_1524871_11	1380390.JIAT01000010_gene4224	1.195e-36	149.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158358_k127_1524871_1	525904.Tter_1650	4.277e-149	500.0	COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria	2|Bacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158358_k127_1524871_8	670487.Ocepr_1065	3.853e-53	203.0	COG1307@1|root,COG1307@2|Bacteria,1WIY0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158358_k127_1524871_15	67267.JNXT01000004_gene4891	1.075e-20	100.0	COG2197@1|root,COG2197@2|Bacteria,2IGCB@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158358_k127_1524871_2	1158614.I592_00267	5.518e-108	374.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,4B0J0@81852|Enterococcaceae	91061|Bacilli	S	Dak1_2	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158358_k127_1524871_17	926692.AZYG01000034_gene2400	7.866e-15	78.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3WASB@53433|Halanaerobiales	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158358_k127_1524871_16	469383.Cwoe_3704	1.246e-17	89.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4CQUE@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158358_k127_1524871_13	1262914.BN533_01539	1.449e-32	139.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4H3ZR@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158358_k127_1524871_0	469383.Cwoe_3706	5.641e-182	592.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158358_k127_1524871_7	867903.ThesuDRAFT_01452	3.984e-54	196.0	COG0108@1|root,COG0307@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0307@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WCXY@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
SRR25158358_k127_1524871_12	1120934.KB894438_gene4944	4.107e-34	137.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4DZBS@85010|Pseudonocardiales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158358_k127_1524871_10	572477.Alvin_1772	1.798e-41	162.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158358_k127_1524871_9	469383.Cwoe_3720	1.351e-51	190.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158358_k127_1524871_14	68219.JNXI01000035_gene138	3.025e-25	113.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158358_k127_1524871_3	469383.Cwoe_3722	1.215e-82	291.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4CPIX@84995|Rubrobacteria	84995|Rubrobacteria	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158358_k127_1524871_4	1122939.ATUD01000004_gene3768	1.675e-64	229.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CQ89@84995|Rubrobacteria	84995|Rubrobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158358_k127_1525523_3	1380390.JIAT01000011_gene2342	3.672e-18	96.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria,4CU68@84995|Rubrobacteria	84995|Rubrobacteria	CO	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	-	-	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158358_k127_1525523_0	1380390.JIAT01000011_gene2341	5.919e-169	547.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4CPT3@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158358_k127_1525523_2	1380390.JIAT01000011_gene2340	1.91e-110	368.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4CQE5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158358_k127_1525523_1	2074.JNYD01000005_gene3139	8.349e-159	514.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158358_k127_1532835_3	28042.GU90_06610	6.188e-07	53.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4E1KU@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_1532835_1	479434.Sthe_3503	1.931e-38	156.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	MA20_35610	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158358_k127_1532835_2	1209984.BN978_03399	4.584e-34	144.0	COG2186@1|root,COG2186@2|Bacteria,2GPNU@201174|Actinobacteria,23EYF@1762|Mycobacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_1532835_0	795797.C497_06389	2.267e-42	161.0	COG0145@1|root,arCOG01511@2157|Archaea,2XT1J@28890|Euryarchaeota,23SV5@183963|Halobacteria	183963|Halobacteria	E	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_1545560_0	1101188.KI912155_gene1975	1.851e-264	827.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158358_k127_1545560_2	33876.JNXY01000040_gene6761	5.216e-67	243.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4DB2G@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158358_k127_1545560_3	1173027.Mic7113_2000	4.461e-28	121.0	COG1335@1|root,COG1335@2|Bacteria,1G06D@1117|Cyanobacteria,1H6ZI@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158358_k127_1545560_4	1404245.CGLY_02550	1.779e-20	101.0	COG1802@1|root,COG1802@2|Bacteria,2IGZT@201174|Actinobacteria,22N2C@1653|Corynebacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_1545560_1	1395571.TMS3_0109175	4.443e-217	695.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,1RYWP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158358_k127_1545987_2	479434.Sthe_1716	5.991e-176	569.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia	189775|Thermomicrobia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158358_k127_1545987_12	1380390.JIAT01000009_gene1524	3.95e-32	142.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158358_k127_1545987_11	469383.Cwoe_0792	1.23e-38	166.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4CRYZ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158358_k127_1545987_5	272123.Anacy_4208	7.756e-106	359.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1HM34@1161|Nostocales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158358_k127_1545987_0	595460.RRSWK_03757	0.0	1542.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2IYDT@203682|Planctomycetes	203682|Planctomycetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158358_k127_1545987_15	1380390.JIAT01000011_gene2347	2.989e-21	100.0	COG1226@1|root,COG1226@2|Bacteria,2HPDW@201174|Actinobacteria,4CQRY@84995|Rubrobacteria	84995|Rubrobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158358_k127_1545987_3	748247.AZKH_2874	8.178e-146	476.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158358_k127_1545987_16	1463934.JOCF01000067_gene5224	1.689e-16	85.0	2BVHN@1|root,332R2@2|Bacteria,2IFVR@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1545987_10	42256.RradSPS_2594	1.864e-56	212.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_1545987_8	745776.DGo_CA0754	9.485e-68	254.0	COG2309@1|root,COG2309@2|Bacteria,1WI2X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158358_k127_1545987_7	68170.KL590490_gene861	2.595e-83	306.0	COG1501@1|root,COG1501@2|Bacteria	68170.KL590490_gene861|-	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1545987_9	68170.KL590490_gene862	1.31e-59	233.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	yihQ	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929	3.2.1.177,3.2.1.199	ko:K01811,ko:K15922	-	-	R00802,R11543	RC00028,RC00059,RC00077,RC00451	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SRR25158358_k127_1545987_1	889378.Spiaf_1960	2.661e-256	805.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158358_k127_1545987_13	469383.Cwoe_0799	1.006e-31	130.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CQBV@84995|Rubrobacteria	84995|Rubrobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158358_k127_1545987_6	266117.Rxyl_0786	6.196e-101	344.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CPEG@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158358_k127_1545987_14	1283299.AUKG01000001_gene1457	1.503e-31	126.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CQCY@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158358_k127_1545987_4	1210884.HG799465_gene12283	1.52e-137	449.0	COG0542@1|root,COG0542@2|Bacteria,2IWYZ@203682|Planctomycetes	203682|Planctomycetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158358_k127_1547996_0	35754.JNYJ01000038_gene5019	8.536e-54	194.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4DCJX@85008|Micromonosporales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ggtA	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158358_k127_1547996_2	2002.JOEQ01000005_gene3738	3.536e-40	158.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2GKSH@201174|Actinobacteria,4EJVM@85012|Streptosporangiales	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158358_k127_1547996_1	285514.JNWO01000030_gene1085	1.31e-52	195.0	COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
SRR25158358_k127_1549135_1	1206101.AZXC01000020_gene5224	9.437e-114	383.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_1549135_0	1283299.AUKG01000006_gene757	4.134e-256	816.0	COG1042@1|root,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CRR1@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-binding	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158358_k127_1553716_5	426716.JOAJ01000011_gene6464	1.052e-34	147.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_1553716_1	469383.Cwoe_5827	7.576e-64	234.0	COG3481@1|root,COG3481@2|Bacteria,2HPRJ@201174|Actinobacteria,4CR4T@84995|Rubrobacteria	84995|Rubrobacteria	S	OB-fold nucleic acid binding domain	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
SRR25158358_k127_1553716_2	1380390.JIAT01000014_gene6028	1.241e-57	226.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4CS23@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158358_k127_1553716_3	1380390.JIAT01000009_gene2014	1.785e-51	204.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158358_k127_1553716_7	1128421.JAGA01000001_gene2433	4.967e-16	86.0	2AWFS@1|root,31NC1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1553716_0	1386089.N865_14840	1.046e-110	368.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4FEXA@85021|Intrasporangiaceae	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158358_k127_1553716_4	1120934.KB894418_gene1990	4.601e-48	181.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4DX5I@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158358_k127_1553716_6	631362.Thi970DRAFT_02433	1.272e-16	79.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158358_k127_1569477_2	1174528.JH992898_gene2508	7.297e-23	105.0	COG0500@1|root,COG2226@2|Bacteria,1G5M2@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158358_k127_1569477_3	1054860.KB913030_gene5490	5.684e-06	57.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria	201174|Actinobacteria	K	helix-turn-helix- domain containing protein, AraC type	alkA	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158358_k127_1569477_0	68260.JOAY01000035_gene2499	6.126e-77	266.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158358_k127_1569477_1	941449.dsx2_1833	1.262e-32	135.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2MAEX@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM 6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158358_k127_1578575_2	1121374.KB891589_gene46	3.902e-58	208.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158358_k127_1578575_0	1032480.MLP_37580	7.644e-92	312.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DNPK@85009|Propionibacteriales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158358_k127_1578575_4	36809.MAB_4841	9.582e-28	115.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,23A4J@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158358_k127_1578575_1	1370121.AUWS01000022_gene6368	2.104e-82	284.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,238HE@1762|Mycobacteriaceae	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_1578575_3	765912.Thimo_3175	5.839e-36	142.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158358_k127_1588459_2	42256.RradSPS_1910	1.168e-14	76.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CQ1A@84995|Rubrobacteria	84995|Rubrobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158358_k127_1588459_3	930169.B5T_02312	4.476e-05	52.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XIN1@135619|Oceanospirillales	135619|Oceanospirillales	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158358_k127_1588459_1	1125863.JAFN01000001_gene3323	5.271e-39	151.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158358_k127_1588459_0	1380390.JIAT01000011_gene2615	9.647e-76	259.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158358_k127_1590062_1	525904.Tter_0363	1.907e-116	383.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
SRR25158358_k127_1590062_4	469383.Cwoe_4643	5.859e-07	51.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPNX@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158358_k127_1590062_2	469383.Cwoe_0999	1.633e-52	198.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158358_k127_1590062_0	1223545.GS4_28_00510	8.388e-169	543.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4GBHD@85026|Gordoniaceae	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158358_k127_1590062_3	1123389.ATXJ01000004_gene1159	1.019e-08	63.0	COG0147@1|root,COG0147@2|Bacteria,1WI8S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158358_k127_1596618_3	1146883.BLASA_0947	2.189e-10	71.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_4,Reg_prop,Y_Y_Y
SRR25158358_k127_1596618_1	469383.Cwoe_0615	1.908e-42	163.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4CQ2W@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158358_k127_1596618_0	309801.trd_0179	2.435e-71	251.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,27XTE@189775|Thermomicrobia	189775|Thermomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158358_k127_1596618_2	1380394.JADL01000009_gene3405	1.133e-10	63.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria	1224|Proteobacteria	L	5'-3' exonuclease	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158358_k127_1599425_1	469383.Cwoe_3688	1.001e-65	242.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158358_k127_1599425_2	469383.Cwoe_3689	6.023e-46	175.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CPZ4@84995|Rubrobacteria	84995|Rubrobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158358_k127_1599425_4	42256.RradSPS_1388	5.862e-23	100.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158358_k127_1599425_0	1121472.AQWN01000002_gene2329	2.069e-76	269.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158358_k127_1599425_5	1304885.AUEY01000008_gene2068	8.197e-18	85.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,2MMB1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158358_k127_1599425_3	469383.Cwoe_3693	1.1e-29	129.0	COG1399@1|root,COG1399@2|Bacteria,2HQSM@201174|Actinobacteria,4CSGR@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158358_k127_1599425_6	1283299.AUKG01000001_gene1628	2.895e-12	78.0	COG2304@1|root,COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
SRR25158358_k127_1603705_2	105425.BBPL01000038_gene2875	3.883e-80	280.0	COG0477@1|root,COG2814@2|Bacteria,2I3AN@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158358_k127_1603705_6	1179773.BN6_30820	3.053e-36	144.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,4DZC1@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	acnR	GO:0000287,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21962	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158358_k127_1603705_3	2002.JOEQ01000002_gene4358	1.878e-73	264.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4EJ84@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158358_k127_1603705_5	469383.Cwoe_2874	2.622e-37	148.0	COG0741@1|root,COG0741@2|Bacteria,2GWDB@201174|Actinobacteria,4CQ5G@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158358_k127_1603705_7	266117.Rxyl_2023	1.004e-20	104.0	COG0237@1|root,COG0237@2|Bacteria,2HG2S@201174|Actinobacteria,4CQK0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158358_k127_1603705_1	469383.Cwoe_2872	4.667e-174	562.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158358_k127_1603705_0	1232410.KI421418_gene2160	4.168e-188	618.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43RY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase A domain	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158358_k127_1603705_4	263358.VAB18032_18825	1.836e-46	181.0	COG0454@1|root,COG0456@2|Bacteria,2I5PT@201174|Actinobacteria,4DFW2@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158358_k127_1603705_8	1232410.KI421420_gene3219	1.233e-07	64.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria,43U08@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158358_k127_1617053_8	1122201.AUAZ01000003_gene1986	9.981e-21	95.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,469RM@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.54,1.2.1.99	ko:K09472,ko:K12254	ko00330,ko01100,map00330,map01100	M00136	R02549,R03177,R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158358_k127_1617053_6	1415780.JPOG01000001_gene1859	4.343e-75	271.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1X5W3@135614|Xanthomonadales	135614|Xanthomonadales	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1617053_3	1385510.N781_15770	3.999e-106	362.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HF1Z@91061|Bacilli,2YBCE@289201|Pontibacillus	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_1617053_7	1416759.AYMR01000011_gene376	1.866e-28	122.0	COG1795@1|root,COG1795@2|Bacteria,2IGCK@201174|Actinobacteria	201174|Actinobacteria	S	Formaldehyde-activating enzyme (Fae)	-	-	4.2.1.147	ko:K10713	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R08058	RC01583,RC01795	ko00000,ko00001,ko01000	-	-	-	Fae
SRR25158358_k127_1617053_5	1449357.JQLK01000005_gene2419	1.442e-92	318.0	COG1062@1|root,COG1062@2|Bacteria,1WKA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1617053_0	754035.Mesau_05210	1.032e-268	854.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,43HW8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158358_k127_1617053_4	1380391.JIAS01000004_gene2985	1.267e-98	346.0	COG1173@1|root,COG1173@2|Bacteria,1R7UQ@1224|Proteobacteria,2U4Q2@28211|Alphaproteobacteria,2JV9K@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158358_k127_1617053_2	1449065.JMLL01000010_gene436	6.16e-117	385.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2U217@28211|Alphaproteobacteria,43NSF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158358_k127_1617053_1	1408418.JNJH01000055_gene1543	6.132e-132	439.0	COG0747@1|root,COG0747@2|Bacteria,1MXB1@1224|Proteobacteria,2U12E@28211|Alphaproteobacteria,2JZH7@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158358_k127_1617053_9	219305.MCAG_04085	1.148e-10	67.0	COG1414@1|root,COG1414@2|Bacteria,2GP2W@201174|Actinobacteria,4DCDC@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158358_k127_1620618_4	1385520.N802_04265	1.431e-34	139.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4FJH5@85021|Intrasporangiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158358_k127_1620618_1	344747.PM8797T_16917	6.767e-119	393.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158358_k127_1620618_6	1227453.C444_13417	3.059e-17	83.0	arCOG04557@1|root,arCOG04557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1620618_2	1306174.JODP01000019_gene4612	4.409e-109	382.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158358_k127_1620618_3	1380390.JIAT01000010_gene3849	1.795e-98	341.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria	2|Bacteria	T	HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5
SRR25158358_k127_1620618_0	1535287.JP74_10975	3.796e-149	481.0	COG1649@1|root,COG1649@2|Bacteria,1R6SN@1224|Proteobacteria,2U2S1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1620618_8	1122132.AQYH01000020_gene192	1.808e-06	57.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,4B9P2@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1621353_0	1510531.JQJJ01000002_gene5002	2.449e-165	523.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3JWN0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158358_k127_1621353_1	1123060.JONP01000005_gene5751	1.217e-114	376.0	COG1712@1|root,COG1712@2|Bacteria,1MX8S@1224|Proteobacteria,2TV48@28211|Alphaproteobacteria,2JREV@204441|Rhodospirillales	204441|Rhodospirillales	H	Domain of unknown function DUF108	-	-	-	-	-	-	-	-	-	-	-	-	DUF108,NAD_binding_3
SRR25158358_k127_1621353_2	1510531.JQJJ01000002_gene4999	1.537e-96	332.0	COG0684@1|root,COG0684@2|Bacteria,1QSHP@1224|Proteobacteria,2U948@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158358_k127_1621353_3	351016.RAZWK3B_09896	2.158e-81	280.0	COG3473@1|root,COG3473@2|Bacteria,1RKZQ@1224|Proteobacteria,2U13U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158358_k127_1624541_3	43354.JOIJ01000001_gene396	1.013e-25	119.0	COG3147@1|root,COG3147@2|Bacteria,2GYC2@201174|Actinobacteria,4ECZ4@85010|Pseudonocardiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1624541_0	1122939.ATUD01000004_gene3916	1.91e-147	495.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CP5W@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158358_k127_1624541_1	266117.Rxyl_0836	3.281e-116	387.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria,4CQFE@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase, class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158358_k127_1624541_2	469383.Cwoe_5770	3.57e-84	293.0	COG0348@1|root,COG0348@2|Bacteria,2I6I5@201174|Actinobacteria,4CS5U@84995|Rubrobacteria	84995|Rubrobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1627959_1	1380390.JIAT01000009_gene340	9.078e-215	679.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CP9Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158358_k127_1627959_2	1408424.JHYI01000015_gene4731	1.954e-14	80.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158358_k127_1627959_0	1120949.KB903294_gene4614	0.0	1358.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DB0D@85008|Micromonosporales	201174|Actinobacteria	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158358_k127_1631261_1	469383.Cwoe_2191	3.349e-128	418.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4CT3Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158358_k127_1631261_0	469383.Cwoe_2192	3.014e-152	492.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CPUE@84995|Rubrobacteria	201174|Actinobacteria	C	PFAM Transketolase central region	pdhB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2496c	Transket_pyr,Transketolase_C
SRR25158358_k127_1631261_2	469383.Cwoe_2193	3.123e-99	339.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158358_k127_1631261_3	469383.Cwoe_5938	9.719e-39	157.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158358_k127_1636532_3	1313172.YM304_37720	3.128e-07	61.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	spoIVFA	-	-	ko:K06194,ko:K06401,ko:K21472,ko:K21473	-	-	-	-	ko00000,ko01000,ko01002,ko01011	1.A.34.1.2	-	-	LysM,Peptidase_M23
SRR25158358_k127_1636532_2	1122939.ATUD01000017_gene4040	4.546e-71	254.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CPQ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158358_k127_1636532_1	469383.Cwoe_4639	6.107e-77	269.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CPAU@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158358_k127_1636532_0	1122939.ATUD01000017_gene4042	4.918e-116	383.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
SRR25158358_k127_1637396_0	525904.Tter_0058	1.709e-144	468.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158358_k127_1637396_2	338963.Pcar_2169	4.488e-128	427.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,43S0K@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	GatB domain	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158358_k127_1637396_1	405948.SACE_1163	5.725e-131	428.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4E55Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158358_k127_1637396_3	1121440.AUMA01000007_gene1143	1.324e-56	201.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MB2S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158358_k127_1637396_4	1146883.BLASA_0701	2.56e-13	77.0	COG1622@1|root,COG1622@2|Bacteria,2GS05@201174|Actinobacteria	201174|Actinobacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158358_k127_1637396_5	1122939.ATUD01000002_gene1249	1.131e-10	66.0	arCOG02771@1|root,2Z8A4@2|Bacteria,2GNG0@201174|Actinobacteria,4CU6S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1639322_2	1312954.KI914885_gene2560	8.776e-22	103.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,1W87C@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158358_k127_1639322_0	309801.trd_1438	8.586e-222	697.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158358_k127_1639322_1	1380390.JIAT01000014_gene6094	9.852e-98	330.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158358_k127_1651012_0	867845.KI911784_gene724	1.327e-105	345.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi,3767V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K15052	ko00720,ko01200,map00720,map01200	M00376	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158358_k127_1651012_1	479434.Sthe_3502	1.845e-96	335.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	2|Bacteria	C	Proline dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158358_k127_1651012_3	1382304.JNIL01000001_gene3039	3.869e-29	128.0	COG0329@1|root,COG0329@2|Bacteria,1TPVS@1239|Firmicutes,4HATJ@91061|Bacilli	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158358_k127_1651012_2	1207063.P24_09326	4.282e-65	231.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,2JQK7@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158358_k127_1653193_2	1146883.BLASA_4759	2.246e-80	278.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,4EWMM@85013|Frankiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_1653193_1	35754.JNYJ01000001_gene7191	1.909e-83	285.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4D9DX@85008|Micromonosporales	201174|Actinobacteria	C	Cysteine-rich domain	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158358_k127_1653193_0	886293.Sinac_5813	4.102e-183	597.0	COG1139@1|root,COG1139@2|Bacteria,2IX00@203682|Planctomycetes	203682|Planctomycetes	C	electron transport protein ykgF-putative 4Fe-4S containing oxidoreductase	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158358_k127_1653193_3	66373.JOFQ01000005_gene3894	8.313e-46	174.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised ACR, YkgG family COG1556	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158358_k127_1653193_4	469371.Tbis_0113	6.201e-13	78.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4E1BJ@85010|Pseudonocardiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158358_k127_1660681_3	1380390.JIAT01000011_gene2659	1.484e-07	63.0	2AWTN@1|root,31NQQ@2|Bacteria,2HR9K@201174|Actinobacteria,4CT69@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1660681_2	1313172.YM304_29620	7.402e-75	263.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	mscS	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
SRR25158358_k127_1660681_0	1137271.AZUM01000006_gene432	1.983e-147	483.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4E06F@85010|Pseudonocardiales	201174|Actinobacteria	I	Phospholipase D Active site motif	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,PLDc_2
SRR25158358_k127_1660681_1	469383.Cwoe_4266	1.616e-92	312.0	COG2172@1|root,COG2345@1|root,COG2172@2|Bacteria,COG2345@2|Bacteria,2IERP@201174|Actinobacteria	201174|Actinobacteria	K	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158358_k127_1661129_6	469383.Cwoe_2844	2.155e-25	111.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158358_k127_1661129_2	1122915.AUGY01000140_gene3200	1.745e-62	231.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,26S27@186822|Paenibacillaceae	91061|Bacilli	J	30S ribosomal protein S12 methylthiotransferase	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158358_k127_1661129_8	110319.CF8_1577	9.907e-23	104.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158358_k127_1661129_5	1385514.N782_07225	8.884e-29	120.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,2YAFT@289201|Pontibacillus	91061|Bacilli	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158358_k127_1661129_0	1380390.JIAT01000016_gene5627	7.908e-129	420.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158358_k127_1661129_9	1118060.CAGZ01000024_gene545	6.969e-17	85.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CVZI@84998|Coriobacteriia	84998|Coriobacteriia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158358_k127_1661129_3	293826.Amet_3030	3.816e-57	207.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,36DSP@31979|Clostridiaceae	186801|Clostridia	IM	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
SRR25158358_k127_1661129_7	292.DM42_7354	5.833e-24	116.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2VX20@28216|Betaproteobacteria,1K7B4@119060|Burkholderiaceae	28216|Betaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158358_k127_1661129_1	469383.Cwoe_2851	2.875e-73	260.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158358_k127_1661129_4	1122622.ATWJ01000002_gene800	6.317e-46	176.0	COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158358_k127_166697_0	469383.Cwoe_2203	1.772e-73	255.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158358_k127_166697_1	65497.JODV01000013_gene2310	1.572e-34	144.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4DX5P@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158358_k127_166697_2	526225.Gobs_3292	5.237e-30	128.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria,4ES88@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glycos_transf_2
SRR25158358_k127_1679484_2	996637.SGM_4023	1.807e-29	124.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1679484_1	469383.Cwoe_1023	6.908e-86	293.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4CR64@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158358_k127_1679484_3	1968.JOEV01000040_gene255	9.115e-05	53.0	COG1141@1|root,COG1141@2|Bacteria,2IR4H@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SRR25158358_k127_1679484_0	1122132.AQYH01000004_gene1486	5.888e-101	339.0	COG0667@1|root,COG0667@2|Bacteria,1MWGQ@1224|Proteobacteria,2TUJ8@28211|Alphaproteobacteria,4BDPI@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SRR25158358_k127_1691769_0	1303518.CCALI_00921	7.695e-176	561.0	COG0556@1|root,COG0556@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrB	-	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158358_k127_1691769_1	1289387.AUKW01000013_gene4167	7.787e-27	126.0	COG3391@1|root,COG3391@2|Bacteria,2H069@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1697374_3	387631.Asulf_00922	2.453e-23	110.0	COG1520@1|root,COG1689@1|root,COG3979@1|root,arCOG02554@1|root,arCOG02479@2157|Archaea,arCOG02554@2157|Archaea,arCOG04438@2157|Archaea,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	CBM_6,DUF4430,NosD,PKD,PQQ_2,PQQ_3,Prenyltrans,SQHop_cyclase_C,S_layer_C
SRR25158358_k127_1697374_0	1380390.JIAT01000010_gene4448	3.58e-255	806.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158358_k127_1697374_1	448385.sce0310	1.24e-88	314.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158358_k127_1697374_4	1298863.AUEP01000006_gene3404	9.209e-23	103.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4DRP0@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158358_k127_1697374_2	36630.CADNFIAP00004603	1.679e-29	124.0	2CUWZ@1|root,2RPHZ@2759|Eukaryota,38T8H@33154|Opisthokonta,3PUXW@4751|Fungi,3RE5V@4890|Ascomycota,20QP4@147545|Eurotiomycetes,3SDCI@5042|Eurotiales	4751|Fungi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158358_k127_1697586_3	570268.ANBB01000044_gene1750	1.065e-45	169.0	COG0685@1|root,COG0685@2|Bacteria,2GJ6U@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158358_k127_1697586_1	2074.JNYD01000002_gene5789	1.026e-111	371.0	COG1410@1|root,COG1410@2|Bacteria,2IC7C@201174|Actinobacteria	201174|Actinobacteria	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158358_k127_1697586_0	367299.JOEE01000012_gene3263	1.279e-264	842.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2HE4H@201174|Actinobacteria,4FIQA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRR25158358_k127_1697586_2	748247.AZKH_p0168	4.634e-66	237.0	28I8Y@1|root,2Z8BR@2|Bacteria,1MXN1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
SRR25158358_k127_1697586_5	748247.AZKH_p0167	2.01e-20	97.0	2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria	1224|Proteobacteria	S	Virulence factor	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
SRR25158358_k127_1697586_4	485913.Krac_11240	1.424e-34	140.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_1699131_10	1288083.AUKR01000025_gene3503	8.807e-08	61.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158358_k127_1699131_6	1122222.AXWR01000002_gene2184	2.683e-25	121.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158358_k127_1699131_8	585531.HMPREF0063_10711	1.424e-13	80.0	COG2945@1|root,COG2945@2|Bacteria,2I3PW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Peptidase_S9
SRR25158358_k127_1699131_7	1410665.JNKR01000007_gene661	1.089e-15	85.0	COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4H2KI@909932|Negativicutes	909932|Negativicutes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158358_k127_1699131_4	1283299.AUKG01000002_gene4772	2.289e-61	222.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CSHN@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158358_k127_1699131_3	644966.Tmar_1145	5.93e-64	230.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WD2S@538999|Clostridiales incertae sedis	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158358_k127_1699131_5	42256.RradSPS_1028	5.746e-32	132.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158358_k127_1699131_9	42256.RradSPS_1028	1.212e-12	68.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158358_k127_1699131_0	262724.TT_C0137	2.271e-108	368.0	COG0026@1|root,COG0026@2|Bacteria,1WITC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158358_k127_1699131_2	1303518.CCALI_00052	3.363e-69	242.0	COG0041@1|root,COG0041@2|Bacteria	2|Bacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551	AIRC
SRR25158358_k127_1699131_1	369723.Strop_0423	3.172e-87	291.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4D9AU@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158358_k127_1700569_0	469383.Cwoe_3616	6.465e-110	370.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CP7V@84995|Rubrobacteria	84995|Rubrobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158358_k127_1700569_1	649764.HMPREF0762_01805	1.574e-103	346.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CUGV@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158358_k127_1700569_2	1118054.CAGW01000108_gene3625	1.074e-33	139.0	COG2227@1|root,COG2227@2|Bacteria,1UHU9@1239|Firmicutes,4HFRY@91061|Bacilli,277EV@186822|Paenibacillaceae	91061|Bacilli	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158358_k127_1700569_4	285535.JOEY01000015_gene4211	0.0003308	53.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158358_k127_1700569_3	1283299.AUKG01000002_gene4202	8.869e-06	58.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2GJYH@201174|Actinobacteria,4CT88@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
SRR25158358_k127_1702789_1	1283299.AUKG01000002_gene5315	2.579e-59	216.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158358_k127_1702789_0	1382356.JQMP01000003_gene2532	4.965e-72	250.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158358_k127_1709327_0	258052.JNYV01000006_gene2652	1.39e-111	371.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,2M4WI@2063|Kitasatospora	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158358_k127_1709327_5	1123389.ATXJ01000001_gene595	1.614e-05	57.0	COG0663@1|root,COG0663@2|Bacteria,1WIVI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carbonic anhydrase acetyltransferase isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158358_k127_1709327_4	1267005.KB911255_gene2449	7.579e-11	75.0	COG0110@1|root,COG0508@1|root,COG0110@2|Bacteria,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6,Biotin_lipoyl,E3_binding,Hexapep
SRR25158358_k127_1709327_2	1121406.JAEX01000016_gene1869	6.31e-75	266.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42MBM@68525|delta/epsilon subdivisions,2WJKG@28221|Deltaproteobacteria,2M9IA@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Transket_pyr,Transketolase_C
SRR25158358_k127_1709327_1	1121272.KB903253_gene6882	3.269e-96	323.0	COG1071@1|root,COG1071@2|Bacteria,2HVS4@201174|Actinobacteria,4DD1J@85008|Micromonosporales	201174|Actinobacteria	C	1-deoxy-D-xylulose-5-phosphate synthase	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158358_k127_1709327_3	234267.Acid_1241	4.15e-30	134.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	MA20_44000	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
SRR25158358_k127_1709390_2	1299327.I546_3266	2.963e-27	113.0	COG3328@1|root,COG3328@2|Bacteria,2H9CR@201174|Actinobacteria,2371V@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158358_k127_1709390_0	469383.Cwoe_4548	2.644e-205	657.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CPKI@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158358_k127_1709390_3	1380390.JIAT01000009_gene2043	2.255e-18	92.0	COG1595@1|root,COG1595@2|Bacteria,2HY6G@201174|Actinobacteria,4CQBA@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_1709390_4	590998.Celf_1233	1.048e-05	57.0	COG3206@1|root,COG3206@2|Bacteria,2GPMH@201174|Actinobacteria,4F2H2@85016|Cellulomonadaceae	201174|Actinobacteria	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158358_k127_1709390_1	309799.DICTH_0982	1.295e-52	191.0	COG3707@1|root,COG3707@2|Bacteria	2|Bacteria	T	response regulator	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158358_k127_1709414_6	570268.ANBB01000057_gene4138	4.099e-25	107.0	2BYGI@1|root,333FU@2|Bacteria,2GRMH@201174|Actinobacteria,4EPV2@85012|Streptosporangiales	201174|Actinobacteria	S	Subtilisin inhibitor-like	-	-	-	-	-	-	-	-	-	-	-	-	SSI
SRR25158358_k127_1709414_2	649638.Trad_0575	3.545e-68	241.0	COG3823@1|root,COG3823@2|Bacteria,1WM89@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
SRR25158358_k127_1709414_5	1307759.JOMJ01000003_gene1562	2.015e-27	128.0	COG0223@1|root,COG0726@1|root,COG0223@2|Bacteria,COG0726@2|Bacteria,1MWH1@1224|Proteobacteria,42M1P@68525|delta/epsilon subdivisions,2X6C3@28221|Deltaproteobacteria,2MD6Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Formyl transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158358_k127_1709414_8	1192034.CAP_6009	2.296e-07	59.0	2EJTG@1|root,33DI3@2|Bacteria,1NG9N@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
SRR25158358_k127_1709414_4	1461580.CCAS010000017_gene2009	4.013e-36	149.0	COG0438@1|root,COG0438@2|Bacteria,1UJHE@1239|Firmicutes,4HGAK@91061|Bacilli,1ZE94@1386|Bacillus	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glycos_transf_1
SRR25158358_k127_1709414_3	469383.Cwoe_0093	1.956e-67	251.0	COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria,4CRDA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158358_k127_1709414_0	479434.Sthe_3153	4.008e-128	421.0	COG1108@1|root,COG1108@2|Bacteria,2G7XS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158358_k127_1709414_1	479434.Sthe_3154	1.099e-106	360.0	COG1108@1|root,COG1108@2|Bacteria,2G5VY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158358_k127_1709414_7	1521187.JPIM01000062_gene2441	1.269e-23	100.0	COG1121@1|root,COG1121@2|Bacteria,2G5WQ@200795|Chloroflexi,374U1@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K11710	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158358_k127_1711620_4	103733.JNYO01000014_gene3716	1.158e-24	106.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4E278@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_1711620_3	523841.HFX_1715	2.243e-30	126.0	COG1611@1|root,arCOG02431@2157|Archaea,2XXTK@28890|Euryarchaeota,23W2P@183963|Halobacteria	183963|Halobacteria	K	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158358_k127_1711620_0	471852.Tcur_1041	5.494e-104	361.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4EFJN@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158358_k127_1711620_2	105425.BBPL01000074_gene3820	9.145e-51	192.0	COG1670@1|root,COG1670@2|Bacteria,2IQW2@201174|Actinobacteria,2NI3J@228398|Streptacidiphilus	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158358_k127_1711620_1	929713.NIASO_02455	1.495e-91	314.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158358_k127_1712922_1	644283.Micau_3207	8.763e-51	198.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria,4DAC5@85008|Micromonosporales	201174|Actinobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
SRR25158358_k127_1712922_0	1283299.AUKG01000001_gene1888	1.017e-95	332.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4CRVV@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158358_k127_1712922_2	103733.JNYO01000022_gene6997	2.389e-20	92.0	COG3483@1|root,COG3483@2|Bacteria,2ICER@201174|Actinobacteria,4E9ZP@85010|Pseudonocardiales	201174|Actinobacteria	E	Tryptophan 2,3-dioxygenase	-	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158358_k127_1721377_0	867903.ThesuDRAFT_01087	3.182e-200	632.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes	1239|Firmicutes	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158358_k127_1721377_2	1229520.ADIAL_0722	1.337e-76	264.0	COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,4HEDP@91061|Bacilli,27GNS@186828|Carnobacteriaceae	91061|Bacilli	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
SRR25158358_k127_1721377_1	105425.BBPL01000061_gene5142	2.002e-81	290.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,2NFVP@228398|Streptacidiphilus	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknJ	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158358_k127_1723446_3	479434.Sthe_3506	2.306e-15	88.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2G7EW@200795|Chloroflexi	200795|Chloroflexi	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR25158358_k127_1723446_2	871963.Desdi_2020	7.268e-16	90.0	COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,24965@186801|Clostridia,261US@186807|Peptococcaceae	186801|Clostridia	M	peptidoglycan-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60,PG_binding_1
SRR25158358_k127_1723446_0	1894.JOER01000001_gene5208	2.435e-34	140.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria	201174|Actinobacteria	K	PFAM flavin reductase domain protein, FMN-binding	pyr9	-	1.5.1.36	ko:K21297,ko:K21727	ko00253,ko00627,ko01057,ko01120,ko01130,map00253,map00627,map01057,map01120,map01130	M00823	R03023	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavin_Reduct
SRR25158358_k127_1723446_1	102129.Lepto7375DRAFT_6627	1.615e-31	135.0	COG0457@1|root,COG0457@2|Bacteria	102129.Lepto7375DRAFT_6627|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1731967_3	1089551.KE386572_gene3635	1.122e-07	54.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2TU1X@28211|Alphaproteobacteria,4BS14@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158358_k127_1731967_0	1122221.JHVI01000008_gene2374	2.188e-202	641.0	COG2225@1|root,COG2225@2|Bacteria,1WIVZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158358_k127_1731967_1	1158050.KB895472_gene2777	1.737e-48	190.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1731967_2	1120950.KB892779_gene990	5.505e-11	70.0	COG3393@1|root,COG3393@2|Bacteria,2GN6B@201174|Actinobacteria,4DRII@85009|Propionibacteriales	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158358_k127_1732146_3	1120797.KB908255_gene544	3.629e-58	216.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,234A6@1762|Mycobacteriaceae	201174|Actinobacteria	E	Monoamine oxidase	aofH_1	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158358_k127_1732146_2	1206101.AZXC01000007_gene2590	5.419e-109	369.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158358_k127_1732146_1	1380391.JIAS01000013_gene3519	6.504e-115	385.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JQQC@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158358_k127_1732146_0	479433.Caci_7453	9.676e-145	471.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria	201174|Actinobacteria	E	(mono)amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158358_k127_1732146_4	1380391.JIAS01000013_gene3518	3.043e-52	189.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,2JQ7X@204441|Rhodospirillales	204441|Rhodospirillales	E	COG1177 ABC-type spermidine putrescine transport system, permease component II	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158358_k127_1733097_0	469383.Cwoe_4241	1.038e-216	693.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4CRVY@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158358_k127_1733097_1	1380390.JIAT01000017_gene5296	2.212e-107	361.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158358_k127_1734107_0	1380390.JIAT01000013_gene145	2.849e-162	550.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158358_k127_1734107_3	1380390.JIAT01000013_gene144	5.864e-19	101.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,CW_binding_1,DUF1929,F5_F8_type_C,FIVAR,He_PIG,Laminin_G_3,Peptidase_M6
SRR25158358_k127_1734107_2	383372.Rcas_3554	2.516e-28	124.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi,3779Z@32061|Chloroflexia	32061|Chloroflexia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158358_k127_1734107_5	1218108.KB908292_gene1537	0.000695	46.0	2EHBZ@1|root,33B3U@2|Bacteria,4NZK3@976|Bacteroidetes,1I71Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1734107_1	1380390.JIAT01000011_gene2559	3.391e-66	232.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4CSEV@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158358_k127_1751646_2	717606.PaecuDRAFT_2262	1.126e-41	173.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,26RDT@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
SRR25158358_k127_1751646_1	298655.KI912266_gene444	9.987e-67	244.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4ERYJ@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158358_k127_1751646_0	469383.Cwoe_2071	2.103e-88	312.0	COG2170@1|root,COG2170@2|Bacteria,2ISM2@201174|Actinobacteria,4CRFQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158358_k127_1756875_0	2074.JNYD01000057_gene2986	1.046e-137	465.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DZTZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_1756875_8	643562.Daes_3249	6.987e-37	157.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42R7J@68525|delta/epsilon subdivisions,2WMT4@28221|Deltaproteobacteria,2MGBE@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_1756875_6	1254432.SCE1572_35130	8.107e-48	178.0	COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,42RRP@68525|delta/epsilon subdivisions,2WP0I@28221|Deltaproteobacteria,2Z3A6@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158358_k127_1756875_5	1206733.BAGC01000041_gene2009	4.21e-48	180.0	2BVHN@1|root,332R2@2|Bacteria,2IFVR@201174|Actinobacteria,4G4NB@85025|Nocardiaceae	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1756875_9	1429046.RR21198_4556	1.266e-34	147.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4G1CN@85025|Nocardiaceae	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158358_k127_1756875_7	330084.JNYZ01000008_gene6609	8.396e-44	170.0	COG1142@1|root,COG1142@2|Bacteria,2IQSG@201174|Actinobacteria	201174|Actinobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1756875_2	861299.J421_0834	1.917e-85	288.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	MA20_24580	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158358_k127_1756875_1	1469245.JFBG01000072_gene74	6.94e-109	362.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1RYQS@1236|Gammaproteobacteria,1WWAX@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158358_k127_1756875_10	1122138.AQUZ01000085_gene8801	2.549e-10	70.0	COG2329@1|root,COG2329@2|Bacteria,2ISIW@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158358_k127_1756875_3	1411123.JQNH01000001_gene2502	5.497e-73	253.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158358_k127_1756875_4	1206731.BAGB01000157_gene5821	4.151e-50	188.0	COG1028@1|root,COG1028@2|Bacteria,2HFPH@201174|Actinobacteria,4G79S@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1758454_3	521098.Aaci_2086	3.48e-30	129.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HG88@91061|Bacilli	91061|Bacilli	K	domain protein	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158358_k127_1758454_0	266117.Rxyl_1174	5.612e-156	509.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158358_k127_1758454_1	266117.Rxyl_1175	5.893e-106	353.0	COG1840@1|root,COG1840@2|Bacteria,2HRRI@201174|Actinobacteria,4CTU6@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158358_k127_1758454_2	266117.Rxyl_1173	7.735e-101	338.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158358_k127_1758474_5	298653.Franean1_2225	0.0003874	48.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria,4ES2U@85013|Frankiales	201174|Actinobacteria	P	PFAM sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158358_k127_1758474_2	266940.Krad_0917	1.881e-39	154.0	COG0490@1|root,COG0490@2|Bacteria,2IFBQ@201174|Actinobacteria	201174|Actinobacteria	P	regulatory, ligand-binding protein related to C-terminal domains of K channels	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158358_k127_1758474_4	709986.Deima_3239	4.516e-05	48.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158358_k127_1758474_3	1205910.B005_1885	1.494e-05	50.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJCN@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158358_k127_1758474_1	1380390.JIAT01000010_gene4785	4.783e-50	181.0	COG3791@1|root,COG3791@2|Bacteria,2HP2J@201174|Actinobacteria,4CQDM@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158358_k127_1758474_0	469383.Cwoe_2632	3.923e-259	814.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	201174|Actinobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_1764341_0	1120973.AQXL01000132_gene2184	1.839e-117	383.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,27852@186823|Alicyclobacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158358_k127_1764341_1	469383.Cwoe_4619	9.73e-80	275.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158358_k127_1764341_2	1123319.AUBE01000015_gene5662	4.817e-59	216.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158358_k127_1764676_1	1380390.JIAT01000009_gene1186	2.037e-17	86.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158358_k127_1764676_0	469383.Cwoe_4536	1.958e-194	625.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158358_k127_1764862_3	1380390.JIAT01000009_gene365	1.363e-72	253.0	COG0438@1|root,COG0438@2|Bacteria,2HPUM@201174|Actinobacteria,4CR8J@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158358_k127_1764862_0	765420.OSCT_1630	2.051e-203	669.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi,376KZ@32061|Chloroflexia	32061|Chloroflexia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158358_k127_1764862_6	1380390.JIAT01000012_gene3016	1.877e-50	187.0	COG1802@1|root,COG1802@2|Bacteria,2HC27@201174|Actinobacteria,4CT90@84995|Rubrobacteria	84995|Rubrobacteria	K	FCD	-	-	-	ko:K21727	ko00627,ko01120,map00627,map01120	-	R03023	RC00046	ko00000,ko00001	-	-	-	FCD,GntR
SRR25158358_k127_1764862_7	309801.trd_1708	5.522e-48	180.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158358_k127_1764862_8	349520.PPE_00637	4.335e-31	131.0	COG1994@1|root,COG1994@2|Bacteria,1TSA9@1239|Firmicutes,4HEQY@91061|Bacilli,26QTJ@186822|Paenibacillaceae	91061|Bacilli	S	Zn-dependent	M1-843	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158358_k127_1764862_5	562973.HMPREF0059_02575	5.602e-65	231.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4D33Q@85005|Actinomycetales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158358_k127_1764862_10	285535.JOEY01000011_gene6004	4.755e-14	80.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158358_k127_1764862_2	234267.Acid_5233	2.194e-90	311.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MB@57723|Acidobacteria	57723|Acidobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158358_k127_1764862_1	483219.LILAB_24505	8.524e-121	403.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158358_k127_1764862_4	208444.JNYY01000012_gene7798	3.41e-69	250.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria,4DZHR@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	phzM	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158358_k127_1764862_9	1380390.JIAT01000009_gene948	1.074e-28	117.0	COG3276@1|root,COG3276@2|Bacteria,2GKF9@201174|Actinobacteria,4CPDU@84995|Rubrobacteria	84995|Rubrobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_3
SRR25158358_k127_1767719_1	471852.Tcur_4960	2.357e-116	383.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4EGF8@85012|Streptosporangiales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158358_k127_1767719_2	1120948.KB903246_gene3359	3.359e-86	300.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4DZEY@85010|Pseudonocardiales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158358_k127_1767719_3	1288484.APCS01000073_gene283	8.271e-14	82.0	2CH9R@1|root,33MNW@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158358_k127_1767719_0	1961.JOAK01000025_gene3605	2.525e-219	691.0	COG0477@1|root,COG0477@2|Bacteria,2GNT8@201174|Actinobacteria	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_1767719_4	1121272.KB903289_gene4401	1.183e-08	61.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DF3X@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1777245_0	42256.RradSPS_3020	1.44e-276	865.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CPE7@84995|Rubrobacteria	84995|Rubrobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158358_k127_1777245_2	42256.RradSPS_0060	1.265e-130	426.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CSJN@84995|Rubrobacteria	84995|Rubrobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158358_k127_1777245_1	1521187.JPIM01000002_gene3134	9.502e-158	524.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158358_k127_1777245_4	1032480.MLP_14240	6.338e-13	82.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4DP29@85009|Propionibacteriales	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158358_k127_1777245_3	298655.KI912266_gene2037	6.744e-74	256.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4ERCV@85013|Frankiales	201174|Actinobacteria	G	PFAM Inositol monophosphatase	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158358_k127_1780927_4	1094980.Mpsy_0064	2.91e-33	145.0	COG4907@1|root,arCOG03432@2157|Archaea,2XVA0@28890|Euryarchaeota,2NA0A@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158358_k127_1780927_2	469383.Cwoe_3618	3.932e-47	177.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CPWM@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA rRNA methyltransferase, SpoU	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158358_k127_1780927_3	105559.Nwat_1876	2.585e-37	144.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1WYQC@135613|Chromatiales	135613|Chromatiales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158358_k127_1780927_5	1239962.C943_01265	1.218e-09	61.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,47RYG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158358_k127_1780927_1	1118060.CAGZ01000033_gene1494	1.494e-48	179.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CUA6@84998|Coriobacteriia	84998|Coriobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158358_k127_1780927_0	390874.Tpet_0189	3.656e-140	457.0	COG0441@1|root,COG0441@2|Bacteria,2GBXU@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158358_k127_1781314_1	929712.KI912613_gene4749	9.322e-87	303.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CPTX@84995|Rubrobacteria	84995|Rubrobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158358_k127_1781314_2	1334046.AYTB01000016_gene891	1.476e-79	276.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,26E26@186818|Planococcaceae	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06615	PALP
SRR25158358_k127_1781314_4	926569.ANT_04930	1.861e-43	169.0	COG0083@1|root,COG0083@2|Bacteria,2G6MP@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158358_k127_1781314_3	1501230.ET33_16070	9.668e-45	172.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,26SN4@186822|Paenibacillaceae	91061|Bacilli	P	3-mercaptopyruvate sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158358_k127_1781314_0	204669.Acid345_3109	3.219e-104	348.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158358_k127_1781403_5	871963.Desdi_3237	2.957e-40	153.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,2606B@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158358_k127_1781403_0	1379698.RBG1_1C00001G1537	6.29e-83	292.0	COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,Hexapep,Hexapep_2
SRR25158358_k127_1781403_2	1128421.JAGA01000002_gene737	6.944e-65	228.0	COG1044@1|root,COG1044@2|Bacteria,2NPGJ@2323|unclassified Bacteria	2|Bacteria	M	Hexapeptide repeat of succinyl-transferase	wbbJ	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
SRR25158358_k127_1781403_4	134676.ACPL_6719	6.16e-46	189.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14645,ko:K14743	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158358_k127_1781403_3	469383.Cwoe_3325	2.272e-49	193.0	COG2385@1|root,COG2385@2|Bacteria,2ID9T@201174|Actinobacteria,4CPMQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158358_k127_1781403_1	479434.Sthe_0968	5.407e-68	235.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,27XGB@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158358_k127_1782186_2	472759.Nhal_3157	4.343e-58	213.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1WXRD@135613|Chromatiales	135613|Chromatiales	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158358_k127_1782186_1	700598.Niako_6329	1.941e-89	304.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1IRDU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158358_k127_1782186_0	1380390.JIAT01000009_gene1787	6.371e-258	812.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CP85@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158358_k127_1791530_2	1461693.ATO10_10540	1.2e-77	267.0	COG0395@1|root,COG0395@2|Bacteria,1R64A@1224|Proteobacteria,2VF04@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158358_k127_1791530_1	1293048.CBMB010000003_gene870	1.72e-79	278.0	COG3839@1|root,arCOG00177@2157|Archaea,2XSVD@28890|Euryarchaeota,23SPV@183963|Halobacteria	183963|Halobacteria	E	COG3839 ABC-type sugar transport systems, ATPase components	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158358_k127_1791530_0	525904.Tter_0973	8.673e-92	314.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	ugpC	-	-	ko:K10112,ko:K10195	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00202,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	iJN678.ggtA	ABC_tran,TOBE,TOBE_2
SRR25158358_k127_1791530_3	479434.Sthe_1361	1.971e-16	82.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM alanine racemase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158358_k127_180363_3	1211814.CAPG01000085_gene3913	8.967e-14	76.0	COG1366@1|root,COG1366@2|Bacteria,1V8XY@1239|Firmicutes,4HK7Y@91061|Bacilli,1ZQUJ@1386|Bacillus	91061|Bacilli	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158358_k127_180363_0	526225.Gobs_0116	7.031e-65	251.0	COG0642@1|root,COG0745@1|root,COG1366@1|root,COG2172@1|root,COG2203@1|root,COG2208@1|root,COG0745@2|Bacteria,COG1366@2|Bacteria,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4ERBM@85013|Frankiales	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA,PAS_3,PAS_4,Response_reg,STAS_2,SpoIIE
SRR25158358_k127_180363_2	1280390.CBQR020000146_gene3772	8.309e-14	83.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,26Z8T@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase-like ATPase domain	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158358_k127_180363_1	1232436.CAPF01000014_gene668	1.02e-53	196.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_1804050_0	56107.Cylst_6101	5.188e-135	455.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158358_k127_1809188_6	1403819.BATR01000019_gene622	3.236e-17	88.0	COG2807@1|root,COG2807@2|Bacteria,46XKN@74201|Verrucomicrobia,2IW54@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRR25158358_k127_1809188_1	649747.HMPREF0083_05520	4.272e-135	447.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158358_k127_1809188_4	1122919.KB905566_gene2750	1.537e-68	250.0	COG3970@1|root,COG3970@2|Bacteria,1U819@1239|Firmicutes,4HDEZ@91061|Bacilli,26V5A@186822|Paenibacillaceae	91061|Bacilli	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158358_k127_1809188_3	1336208.JADY01000020_gene3431	2.831e-76	262.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,2JQMS@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158358_k127_1809188_5	246196.MSMEI_1509	2.106e-26	121.0	COG4910@1|root,COG4910@2|Bacteria,2IN09@201174|Actinobacteria,2395Q@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Dehydratase small subunit	pduE	-	4.2.1.28	ko:K13920	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_SU
SRR25158358_k127_1809188_0	246196.MSMEI_6155	2.944e-202	658.0	COG4909@1|root,COG4909@2|Bacteria,2GP0B@201174|Actinobacteria,2346F@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Dehydratase large subunit	-	-	4.2.1.28	ko:K01699	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_LU,Dehydratase_MU
SRR25158358_k127_1809188_7	1155714.KB891999_gene229	2.806e-06	58.0	29YYF@1|root,30KV9@2|Bacteria,2GYTN@201174|Actinobacteria	201174|Actinobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158358_k127_1809188_2	44251.PDUR_10295	2.834e-102	336.0	COG0667@1|root,COG0667@2|Bacteria,1TRHN@1239|Firmicutes,4H9ZV@91061|Bacilli,26RRE@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158358_k127_1809943_2	1499967.BAYZ01000090_gene4936	6.76e-42	168.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158358_k127_1809943_1	391625.PPSIR1_13430	2.659e-73	262.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2WS0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158358_k127_1809943_0	439235.Dalk_1526	9.743e-119	420.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158358_k127_1815792_2	1123065.ATWL01000001_gene180	1.42e-14	78.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158358_k127_1815792_0	42256.RradSPS_1881	2.101e-63	228.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158358_k127_1815792_3	1504672.669787596	3.15e-11	73.0	COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,2VUC9@28216|Betaproteobacteria,4AJIW@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3
SRR25158358_k127_1815792_1	1089551.KE386572_gene226	2.559e-21	104.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BS82@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158358_k127_1817982_0	95619.PM1_0213980	1.904e-141	466.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158358_k127_1817982_1	1435356.Y013_22725	1.173e-12	72.0	COG5470@1|root,COG5470@2|Bacteria,2IQ47@201174|Actinobacteria,4G20Z@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158358_k127_1821800_0	1366050.N234_36235	1.098e-132	426.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2VMAI@28216|Betaproteobacteria,1JZMB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158358_k127_1821800_1	1037409.BJ6T_23810	5.223e-110	376.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158358_k127_1821800_2	477641.MODMU_2271	3.695e-86	306.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4ESTX@85013|Frankiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158358_k127_1821800_3	502025.Hoch_3169	5.733e-43	172.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,43ACN@68525|delta/epsilon subdivisions,2X5SI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158358_k127_1821800_5	1297569.MESS2_1540016	2.442e-27	119.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158358_k127_1821800_4	1297569.MESS2_1540015	2.165e-40	154.0	COG1917@1|root,COG1917@2|Bacteria,1PR0C@1224|Proteobacteria,2VA5E@28211|Alphaproteobacteria,43QMP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_1821800_6	1123065.ATWL01000001_gene180	4.482e-13	76.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158358_k127_1829804_2	28444.JODQ01000008_gene1039	2.11e-10	61.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,TIG
SRR25158358_k127_1829804_1	1968.JOEV01000003_gene3206	2.934e-45	173.0	COG2203@1|root,COG2203@2|Bacteria,2I97I@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
SRR25158358_k127_1829804_0	1385520.N802_02185	3.683e-63	232.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158358_k127_1831744_0	237368.SCABRO_01667	3.432e-139	462.0	COG3930@1|root,COG3930@2|Bacteria,2J4QT@203682|Planctomycetes	203682|Planctomycetes	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
SRR25158358_k127_1831744_1	237368.SCABRO_01668	4.815e-82	283.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
SRR25158358_k127_1833823_4	351016.RAZWK3B_09896	4.165e-07	51.0	COG3473@1|root,COG3473@2|Bacteria,1RKZQ@1224|Proteobacteria,2U13U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158358_k127_1833823_3	1123023.JIAI01000007_gene1835	2.742e-33	137.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,4E5EX@85010|Pseudonocardiales	201174|Actinobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158358_k127_1833823_0	1122611.KB903948_gene6778	1.144e-211	677.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4EH5Q@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158358_k127_1833823_1	253839.SSNG_02448	5.823e-119	389.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM PfkB domain protein	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158358_k127_1833823_2	1380390.JIAT01000009_gene1217	1.246e-73	267.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CRGD@84995|Rubrobacteria	84995|Rubrobacteria	G	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158358_k127_1839875_1	326424.FRAAL0172	4.887e-96	318.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4ERV9@85013|Frankiales	201174|Actinobacteria	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158358_k127_1839875_3	391037.Sare_4030	4.832e-27	126.0	COG0477@1|root,COG2814@2|Bacteria,2HX42@201174|Actinobacteria,4D8CP@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	bacE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158358_k127_1839875_0	469383.Cwoe_4647	8.553e-109	361.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CQB3@84995|Rubrobacteria	84995|Rubrobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158358_k127_1839875_2	760568.Desku_0156	3.66e-81	280.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,2615A@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
SRR25158358_k127_1840954_2	146922.JOFU01000009_gene988	6.957e-78	266.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158358_k127_1840954_4	408672.NBCG_00275	2.572e-52	201.0	COG5002@1|root,COG5002@2|Bacteria,2GP6S@201174|Actinobacteria,4DX0G@85009|Propionibacteriales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158358_k127_1840954_8	880073.Calab_0387	7.565e-40	157.0	28TMI@1|root,2ZFV4@2|Bacteria	2|Bacteria	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
SRR25158358_k127_1840954_9	937777.Deipe_1715	1.711e-28	121.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158358_k127_1840954_5	1048834.TC41_3064	3.818e-51	185.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,279SY@186823|Alicyclobacillaceae	91061|Bacilli	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158358_k127_1840954_6	1121385.AQXW01000004_gene3211	1.598e-47	178.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,1ZWXI@145357|Dermacoccaceae	201174|Actinobacteria	I	Belongs to the IspD TarI cytidylyltransferase family. IspD subfamily	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158358_k127_1840954_3	1380390.JIAT01000011_gene2866	7.927e-65	226.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CPVJ@84995|Rubrobacteria	84995|Rubrobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158358_k127_1840954_0	469383.Cwoe_1685	2.798e-145	473.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CP8Q@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
SRR25158358_k127_1840954_1	28444.JODQ01000007_gene5157	8.188e-81	293.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4EGMA@85012|Streptosporangiales	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158358_k127_1840954_7	404589.Anae109_4177	2.095e-46	171.0	COG0454@1|root,COG0456@2|Bacteria,1PYGZ@1224|Proteobacteria,435DK@68525|delta/epsilon subdivisions,2WZR5@28221|Deltaproteobacteria,2Z2JT@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158358_k127_1845212_3	1273538.G159_16960	2.273e-35	149.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,4HIPC@91061|Bacilli,26HE7@186818|Planococcaceae	91061|Bacilli	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158358_k127_1845212_4	1122939.ATUD01000001_gene52	1.57e-22	110.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR25158358_k127_1845212_5	316274.Haur_2651	5.648e-18	94.0	2EP9Z@1|root,33GWR@2|Bacteria,2G98W@200795|Chloroflexi	200795|Chloroflexi	S	LppX_LprAFG lipoprotein	-	-	-	ko:K14954	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
SRR25158358_k127_1845212_0	469383.Cwoe_5934	6.752e-49	190.0	COG1131@1|root,COG1131@2|Bacteria,2HPPS@201174|Actinobacteria,4CR2G@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158358_k127_1845212_2	1283299.AUKG01000001_gene1785	4.636e-40	165.0	COG1668@1|root,COG1668@2|Bacteria,2HNDN@201174|Actinobacteria,4CP6Y@84995|Rubrobacteria	84995|Rubrobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158358_k127_1845212_6	512565.AMIS_49770	8.713e-18	85.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1845212_1	526225.Gobs_2605	2.772e-42	168.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4ERD0@85013|Frankiales	201174|Actinobacteria	E	Dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158358_k127_1846669_4	1283287.KB822576_gene3557	1.19e-09	60.0	COG1280@1|root,COG1280@2|Bacteria,2HRC6@201174|Actinobacteria,4DUDX@85009|Propionibacteriales	201174|Actinobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158358_k127_1846669_0	469383.Cwoe_4383	8.871e-185	598.0	COG2040@1|root,COG2264@1|root,COG2040@2|Bacteria,COG2264@2|Bacteria,2HQK7@201174|Actinobacteria,4CS5N@84995|Rubrobacteria	84995|Rubrobacteria	EJ	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA,S-methyl_trans
SRR25158358_k127_1846669_3	1172188.KB911828_gene4084	2.162e-18	93.0	COG0346@1|root,COG0346@2|Bacteria,2IRPZ@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158358_k127_1846669_2	469383.Cwoe_1942	2.358e-56	213.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1846669_5	1321773.HMPREF9069_00491	1.794e-08	65.0	COG1082@1|root,COG1082@2|Bacteria,2HUUQ@201174|Actinobacteria,4CVPS@84998|Coriobacteriia	84998|Coriobacteriia	G	COGs COG1082 Sugar phosphate isomerase epimerase	-	-	-	ko:K10709	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
SRR25158358_k127_1846669_1	1042156.CXIVA_15960	1.873e-74	273.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,36E3P@31979|Clostridiaceae	186801|Clostridia	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_1851089_0	925409.KI911562_gene202	1.1e-130	440.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158358_k127_1851089_2	1283299.AUKG01000003_gene295	9.11e-29	120.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CQIE@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158358_k127_1851089_3	1380390.JIAT01000009_gene1152	3.253e-28	120.0	COG0839@1|root,COG0839@2|Bacteria,2HNU5@201174|Actinobacteria,4CQ2B@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q3
SRR25158358_k127_1851089_1	469383.Cwoe_1157	3.364e-65	228.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CQRQ@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158358_k127_1851089_4	671143.DAMO_2695	3.514e-15	76.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158358_k127_185940_2	656024.FsymDg_3892	0.0001013	51.0	29WQV@1|root,30IBV@2|Bacteria,2GZ2Y@201174|Actinobacteria,4ETJK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_185940_0	469383.Cwoe_1561	2.629e-131	436.0	COG4262@1|root,COG4262@2|Bacteria,2HNDH@201174|Actinobacteria,4CP6G@84995|Rubrobacteria	84995|Rubrobacteria	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158358_k127_185940_1	1380390.JIAT01000009_gene2045	9.124e-28	123.0	COG0584@1|root,COG0584@2|Bacteria,2HM6Q@201174|Actinobacteria,4CQ8T@84995|Rubrobacteria	84995|Rubrobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
SRR25158358_k127_1863758_7	525904.Tter_2007	8.177e-37	151.0	2CB42@1|root,2Z7Y3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1863758_3	1123242.JH636437_gene6034	3.125e-86	299.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_1863758_9	1054213.HMPREF9946_01496	1.035e-16	85.0	COG0251@1|root,COG0251@2|Bacteria,1REJQ@1224|Proteobacteria,2U70D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	MA20_01450	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158358_k127_1863758_2	479434.Sthe_0189	9.398e-89	310.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158358_k127_1863758_4	448385.sce7867	3.837e-69	250.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158358_k127_1863758_0	1340493.JNIF01000003_gene3500	1.571e-145	471.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	dgoD	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_1863758_6	1057002.KB905370_gene3300	5.537e-40	158.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TVE6@28211|Alphaproteobacteria,4BCFT@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158358_k127_1863758_5	926690.KE386573_gene683	2.632e-47	181.0	COG1250@1|root,arCOG00249@2157|Archaea,2XVWM@28890|Euryarchaeota,23UMT@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158358_k127_1863758_1	1040986.ATYO01000017_gene890	4.677e-110	375.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TR6X@28211|Alphaproteobacteria,43J54@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158358_k127_1863758_8	1299327.I546_0917	8.539e-30	124.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,237AX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_186399_4	1122939.ATUD01000003_gene3530	2.06e-42	158.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CSBR@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158358_k127_186399_7	1444306.JFZC01000025_gene2466	5.448e-28	120.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,26NZJ@186821|Sporolactobacillaceae	91061|Bacilli	S	Iron-sulphur cluster biosynthesis	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158358_k127_186399_8	1283299.AUKG01000003_gene305	4.197e-25	110.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CQ6Q@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158358_k127_186399_3	1068978.AMETH_0484	2.097e-62	226.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4DYGD@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158358_k127_186399_5	1379698.RBG1_1C00001G1052	1.506e-33	136.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SRR25158358_k127_186399_1	326427.Cagg_1046	2.535e-138	457.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi,3751Y@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD1	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158358_k127_186399_6	671143.DAMO_2697	4.184e-30	130.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
SRR25158358_k127_186399_2	1051632.TPY_0862	6.202e-122	406.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WCEN@538999|Clostridiales incertae sedis	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hymB	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRR25158358_k127_186399_0	469383.Cwoe_1155	1.744e-141	476.0	COG1034@1|root,COG1153@1|root,COG1034@2|Bacteria,COG1153@2|Bacteria,2GJGX@201174|Actinobacteria,4CR3F@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158358_k127_1867552_1	1380386.JIAW01000032_gene3450	1.162e-89	303.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,2333T@1762|Mycobacteriaceae	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_1867552_3	471852.Tcur_4538	1.1e-84	290.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4EJGR@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158358_k127_1867552_4	1394178.AWOO02000102_gene8257	3.228e-67	254.0	COG3386@1|root,COG3386@2|Bacteria,2HDRT@201174|Actinobacteria,4EG50@85012|Streptosporangiales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158358_k127_1867552_0	1499686.BN1079_00592	7.01e-219	704.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158358_k127_1867552_2	1122622.ATWJ01000008_gene2607	2.518e-88	301.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,4FJXN@85021|Intrasporangiaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158358_k127_1881633_4	1429851.X548_00610	1.059e-05	56.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1S10R@1236|Gammaproteobacteria,1XC9V@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158358_k127_1881633_1	469383.Cwoe_5905	1.05e-85	289.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	84995|Rubrobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158358_k127_1881633_3	469383.Cwoe_5906	1.254e-78	280.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2I53J@201174|Actinobacteria,4CRVJ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158358_k127_1881633_2	1380390.JIAT01000009_gene1861	9.183e-85	295.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158358_k127_1881633_0	298655.KI912266_gene3496	8.342e-99	354.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4ETWW@85013|Frankiales	201174|Actinobacteria	G	PFAM Glycosyl transferase, family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158358_k127_1885866_3	469383.Cwoe_5267	1.454e-20	95.0	COG2331@1|root,COG2331@2|Bacteria,2HGE7@201174|Actinobacteria,4CQV7@84995|Rubrobacteria	84995|Rubrobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158358_k127_1885866_2	1280390.CBQR020000064_gene1373	3.622e-35	151.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,26RVC@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	lytR1	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158358_k127_1885866_1	469383.Cwoe_5264	5.219e-64	231.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158358_k127_1885866_0	1380390.JIAT01000009_gene748	8.597e-77	265.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158358_k127_1885866_4	1111454.HMPREF1250_1116	1.162e-14	87.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes	909932|Negativicutes	D	Peptidase M23	envC_1	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158358_k127_1886489_3	1047013.AQSP01000130_gene1868	4.147e-31	128.0	COG0407@1|root,COG0407@2|Bacteria,2NQRU@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
SRR25158358_k127_1886489_0	661478.OP10G_0815	3.136e-279	872.0	COG0129@1|root,COG0129@2|Bacteria	2|Bacteria	EG	dihydroxy-acid dehydratase activity	yjhG	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0050401,GO:0071704,GO:0072329,GO:1901575	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
SRR25158358_k127_1886489_2	1463855.JOHV01000004_gene2782	4.278e-62	227.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158358_k127_1886489_1	266117.Rxyl_0532	1.026e-172	548.0	COG2017@1|root,COG2017@2|Bacteria,2IDCU@201174|Actinobacteria	201174|Actinobacteria	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
SRR25158358_k127_1886489_4	1123504.JQKD01000021_gene5717	1.294e-28	119.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VMQ5@28216|Betaproteobacteria,4AJ1X@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1900773_0	1123367.C666_03240	3.617e-33	136.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KV5W@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158358_k127_1900773_4	246200.SPO2903	1.887e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,4NBY2@97050|Ruegeria	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
SRR25158358_k127_1900773_3	469383.Cwoe_1897	5.409e-16	87.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	pbrT	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
SRR25158358_k127_1900773_1	469383.Cwoe_1286	6.931e-21	102.0	COG1520@1|root,COG4993@1|root,COG1520@2|Bacteria,COG4993@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
SRR25158358_k127_1900773_2	929712.KI912613_gene2298	1.928e-19	91.0	28TIQ@1|root,2ZFSJ@2|Bacteria,2I6IR@201174|Actinobacteria,4CSHG@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_190725_0	439235.Dalk_1526	1.221e-67	261.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158358_k127_190725_1	1297569.MESS2_1540015	1.211e-42	161.0	COG1917@1|root,COG1917@2|Bacteria,1PR0C@1224|Proteobacteria,2VA5E@28211|Alphaproteobacteria,43QMP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_190725_2	331869.BAL199_18058	1.344e-18	89.0	COG1309@1|root,COG1309@2|Bacteria,1RBV0@1224|Proteobacteria,2U7VY@28211|Alphaproteobacteria,4BT49@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158358_k127_1910674_2	1110697.NCAST_32_02140	4.853e-30	121.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4G0SU@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158358_k127_1910674_0	929712.KI912613_gene624	2.165e-68	248.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4CPAN@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158358_k127_1910674_1	525904.Tter_0604	3.698e-62	229.0	COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria	2|Bacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283,ko:K08602	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	-
SRR25158358_k127_1919017_0	469383.Cwoe_1313	1.076e-206	652.0	COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria,4CR1F@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158358_k127_1919017_1	991905.SL003B_4208	4.664e-192	614.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,4BPAX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158358_k127_1919017_2	123214.PERMA_1387	1.145e-66	234.0	COG1053@1|root,COG1053@2|Bacteria,2G3PJ@200783|Aquificae	200783|Aquificae	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	sdhA	-	1.3.1.6,1.3.5.1,1.3.5.4	ko:K00239,ko:K18556	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R00402,R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158358_k127_1919923_0	861450.HMPREF0080_01201	7.666e-45	176.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes	909932|Negativicutes	D	Peptidase M23	envC_1	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158358_k127_1920633_1	1306174.JODP01000001_gene4900	1.882e-109	360.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.1,2.6.1.83	ko:K00812,ko:K08969,ko:K10206,ko:K14261	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00034,M00527	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R07396,R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158358_k127_1920633_4	639283.Snov_0211	1.883e-40	159.0	COG0346@1|root,COG0346@2|Bacteria,1NHW0@1224|Proteobacteria,2U2UX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_1920633_0	326427.Cagg_0296	1.229e-132	435.0	COG4091@1|root,COG4091@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,NAD_binding_3,SAF
SRR25158358_k127_1920633_2	1268303.RHODMAR_0771	4.281e-78	268.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1920633_3	1120944.JONS01000014_gene1056	1.871e-62	216.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4D4BV@85005|Actinomycetales	201174|Actinobacteria	E	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158358_k127_1927562_0	318424.EU78_02890	1.123e-109	368.0	COG0687@1|root,COG0687@2|Bacteria,2IBEC@201174|Actinobacteria,234YK@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
SRR25158358_k127_1927562_3	416348.Hlac_2347	3.06e-20	96.0	COG0824@1|root,arCOG01137@2157|Archaea,2XZ99@28890|Euryarchaeota,23WUB@183963|Halobacteria	183963|Halobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158358_k127_1927562_1	1380391.JIAS01000011_gene5426	5.182e-103	348.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_1927562_2	981369.JQMJ01000004_gene3827	5.477e-45	168.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,2NHDP@228398|Streptacidiphilus	201174|Actinobacteria	C	ATP-grasp domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158358_k127_1929470_2	1121033.AUCF01000042_gene2668	4.499e-32	143.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2JRSA@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
SRR25158358_k127_1929470_0	1449355.JQNR01000005_gene5718	3.651e-94	323.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria	201174|Actinobacteria	S	amine oxidase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,DUF1365
SRR25158358_k127_1929470_1	469383.Cwoe_4990	8.2e-47	177.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158358_k127_1930405_5	1122611.KB903967_gene5176	2.166e-48	178.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4EMZJ@85012|Streptosporangiales	201174|Actinobacteria	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
SRR25158358_k127_1930405_9	266117.Rxyl_1186	5.449e-26	112.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158358_k127_1930405_4	42256.RradSPS_0871	8.441e-62	229.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158358_k127_1930405_8	196162.Noca_0864	1.172e-29	128.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4DNGF@85009|Propionibacteriales	201174|Actinobacteria	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158358_k127_1930405_2	935839.JAGJ01000023_gene2460	1.972e-75	271.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4F40W@85017|Promicromonosporaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158358_k127_1930405_13	1229780.BN381_80155	1.091e-09	66.0	COG1920@1|root,COG1920@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158358_k127_1930405_1	926550.CLDAP_02090	1.406e-80	283.0	COG1134@1|root,COG1134@2|Bacteria,2G6D9@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158358_k127_1930405_10	1449346.JQMO01000002_gene616	7.77e-26	112.0	COG0454@1|root,COG0456@2|Bacteria,2I977@201174|Actinobacteria,2M577@2063|Kitasatospora	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158358_k127_1930405_0	861299.J421_4278	1.344e-114	378.0	COG0407@1|root,COG0407@2|Bacteria,1ZTPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158358_k127_1930405_12	1121940.AUDZ01000011_gene1294	3.58e-13	81.0	2DTSS@1|root,33MHM@2|Bacteria,1NJRN@1224|Proteobacteria,1SQ26@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1930405_6	929712.KI912613_gene1085	1.585e-46	178.0	COG1682@1|root,COG1682@2|Bacteria,2HGDB@201174|Actinobacteria,4CQK9@84995|Rubrobacteria	84995|Rubrobacteria	GM	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_1930405_3	1089550.ATTH01000001_gene1897	8.027e-66	247.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,4NGKM@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR25158358_k127_1930405_14	926564.KI911724_gene1985	2.093e-05	56.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158358_k127_1930405_7	497965.Cyan7822_5360	3.503e-41	166.0	COG1216@1|root,COG1216@2|Bacteria,1G2E9@1117|Cyanobacteria,3KGEG@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158358_k127_1930405_11	1173023.KE650771_gene2095	4.982e-21	96.0	COG0438@1|root,COG2242@1|root,COG0438@2|Bacteria,COG2242@2|Bacteria,1FZUY@1117|Cyanobacteria,1JK81@1189|Stigonemataceae	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_11,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_24
SRR25158358_k127_1933964_1	1283299.AUKG01000001_gene2192	3.604e-110	370.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158358_k127_1933964_2	1227487.C474_01896	2.703e-30	132.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XW2T@28890|Euryarchaeota,23U9Q@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158358_k127_1933964_0	1380390.JIAT01000009_gene2137	1.131e-116	391.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158358_k127_1937718_2	1078020.KEK_01910	7.497e-22	99.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,232QE@1762|Mycobacteriaceae	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158358_k127_1937718_0	469383.Cwoe_1934	9.557e-78	269.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158358_k127_1937718_4	313589.JNB_03265	3.156e-15	83.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4FF2A@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_1937718_1	469383.Cwoe_1939	3.388e-76	272.0	COG1028@1|root,COG1028@2|Bacteria,2GX9R@201174|Actinobacteria	201174|Actinobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_1937718_3	1123072.AUDH01000001_gene2841	1.734e-16	87.0	COG1082@1|root,COG1082@2|Bacteria,1Q173@1224|Proteobacteria,2TTFM@28211|Alphaproteobacteria,2JV3E@204441|Rhodospirillales	204441|Rhodospirillales	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158358_k127_1938776_7	443218.AS9A_2587	3.478e-51	190.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1938776_1	469383.Cwoe_3480	1.282e-194	623.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158358_k127_1938776_13	1122939.ATUD01000005_gene2579	0.0007338	47.0	COG2149@1|root,COG2149@2|Bacteria,2HTN4@201174|Actinobacteria,4CSZK@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158358_k127_1938776_11	469383.Cwoe_1696	1.491e-06	59.0	COG2149@1|root,COG2149@2|Bacteria,2HTN4@201174|Actinobacteria,4CSZK@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158358_k127_1938776_8	379066.GAU_3910	1.009e-37	150.0	COG3663@1|root,COG3663@2|Bacteria,1ZTNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158358_k127_1938776_12	591157.SSLG_01894	2.144e-06	56.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,OsmC
SRR25158358_k127_1938776_2	469383.Cwoe_0934	1.564e-121	406.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4CSVS@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158358_k127_1938776_5	485913.Krac_11103	8.94e-78	273.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158358_k127_1938776_9	1206720.BAFQ01000297_gene6658	2.92e-19	94.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria,4G2S5@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158358_k127_1938776_10	443255.SCLAV_3256	1.015e-18	98.0	COG2222@1|root,COG2222@2|Bacteria,2GMCZ@201174|Actinobacteria	201174|Actinobacteria	M	sugar isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SIS
SRR25158358_k127_1938776_4	309801.trd_1505	4.369e-90	312.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158358_k127_1938776_0	1382356.JQMP01000004_gene583	9.576e-264	837.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158358_k127_1938776_6	1071085.KK033114_gene869	2.719e-67	244.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTQI@28890|Euryarchaeota,23SY3@183963|Halobacteria	183963|Halobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158358_k127_1938776_3	469383.Cwoe_5282	5.399e-108	359.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158358_k127_1939391_5	1144275.COCOR_07784	0.0001563	52.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2WQ9K@28221|Deltaproteobacteria,2YXTM@29|Myxococcales	28221|Deltaproteobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158358_k127_1939391_1	1283299.AUKG01000001_gene3236	9.023e-102	361.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158358_k127_1939391_2	1298863.AUEP01000010_gene4480	7.218e-56	203.0	2CAJE@1|root,33XCP@2|Bacteria,2IMDF@201174|Actinobacteria,4DQZ9@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1939391_0	582402.Hbal_2756	2.798e-180	572.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2U0FB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR)	rhmD	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_1939391_3	452662.SJA_C1-13540	1.258e-53	204.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,2K0DM@204457|Sphingomonadales	204457|Sphingomonadales	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158358_k127_1939391_4	469383.Cwoe_1455	1.569e-44	174.0	COG3395@1|root,COG3395@2|Bacteria,2HRX3@201174|Actinobacteria,4CU08@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
SRR25158358_k127_1943197_3	1537715.JQFJ01000002_gene2163	1.051e-26	111.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2K3VX@204457|Sphingomonadales	204457|Sphingomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158358_k127_1943197_1	326427.Cagg_2874	2.322e-33	135.0	COG2059@1|root,COG2059@2|Bacteria,2G6NB@200795|Chloroflexi,375VI@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158358_k127_1943197_0	1121033.AUCF01000030_gene205	7.557e-68	250.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JVUA@204441|Rhodospirillales	204441|Rhodospirillales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
SRR25158358_k127_1943197_2	269799.Gmet_1298	8.714e-27	128.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria,43W33@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158358_k127_1949321_0	479434.Sthe_1776	2.31e-113	396.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158358_k127_1949321_3	479434.Sthe_0194	0.0001465	48.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158358_k127_1949321_1	479434.Sthe_1775	4.597e-86	291.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_1949321_2	990285.RGCCGE502_13414	1.804e-28	121.0	COG1933@1|root,COG2114@1|root,COG3899@1|root,COG1933@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158358_k127_1956734_3	1211115.ALIQ01000032_gene1949	2.857e-31	141.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2TU1X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158358_k127_1956734_0	479435.Kfla_6629	1.223e-99	332.0	COG0826@1|root,COG0826@2|Bacteria,2GKAK@201174|Actinobacteria,4DU0P@85009|Propionibacteriales	201174|Actinobacteria	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
SRR25158358_k127_1956734_5	1283283.ATXA01000020_gene1338	1.879e-13	75.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria,4EW7K@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158358_k127_1956734_4	351160.RCIX2333	1.592e-17	89.0	COG0778@1|root,arCOG00288@2157|Archaea,2Y6YN@28890|Euryarchaeota,2NB04@224756|Methanomicrobia	224756|Methanomicrobia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158358_k127_1956734_1	378806.STAUR_0404	1.459e-95	323.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42RF4@68525|delta/epsilon subdivisions,2WPIV@28221|Deltaproteobacteria,2Z31U@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	glkA	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158358_k127_1956734_2	543728.Vapar_1509	5.528e-69	252.0	COG1028@1|root,COG1028@2|Bacteria,1R4D2@1224|Proteobacteria,2VIMX@28216|Betaproteobacteria,4AJ24@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_1958325_0	2045.KR76_24210	2.421e-24	113.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4DRPH@85009|Propionibacteriales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158358_k127_1958325_1	1121946.AUAX01000034_gene6818	3.244e-21	99.0	COG4226@1|root,COG4226@2|Bacteria,2IKXB@201174|Actinobacteria,4DED5@85008|Micromonosporales	201174|Actinobacteria	S	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	Arc,HicB
SRR25158358_k127_1961979_4	1499967.BAYZ01000062_gene6038	0.000715	50.0	COG0407@1|root,COG0407@2|Bacteria,2NQRU@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
SRR25158358_k127_1961979_3	1229781.C272_07792	1.798e-45	175.0	COG1414@1|root,COG1414@2|Bacteria,2IJV7@201174|Actinobacteria,4F99E@85019|Brevibacteriaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158358_k127_1961979_0	397278.JOJN01000002_gene637	1.233e-102	355.0	COG5012@1|root,COG5012@2|Bacteria,2IEGQ@201174|Actinobacteria,4DTAH@85009|Propionibacteriales	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158358_k127_1961979_2	570268.ANBB01000044_gene1749	1.277e-49	185.0	COG0685@1|root,COG0685@2|Bacteria,2H891@201174|Actinobacteria	201174|Actinobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
SRR25158358_k127_1961979_1	570268.ANBB01000044_gene1750	1.009e-65	232.0	COG0685@1|root,COG0685@2|Bacteria,2GJ6U@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158358_k127_1964261_5	1382306.JNIM01000001_gene3478	3.283e-55	199.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
SRR25158358_k127_1964261_1	469383.Cwoe_3197	3.96e-104	348.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,4CRBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158358_k127_1964261_6	1206741.BAFX01000096_gene4718	2.366e-15	86.0	COG0500@1|root,COG2226@2|Bacteria,2HFGE@201174|Actinobacteria,4FV65@85025|Nocardiaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158358_k127_1964261_7	1380390.JIAT01000014_gene6053	0.00013	55.0	2AW70@1|root,31N21@2|Bacteria,2HQQD@201174|Actinobacteria,4CSD4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1964261_4	1380390.JIAT01000010_gene4858	3.199e-56	202.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4CQBB@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158358_k127_1964261_2	469383.Cwoe_3200	2.053e-101	344.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CPT1@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158358_k127_1964261_0	469383.Cwoe_3201	3.138e-130	432.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158358_k127_1964261_3	926692.AZYG01000074_gene2436	1.724e-79	293.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WB9X@53433|Halanaerobiales	186801|Clostridia	F	PFAM Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158358_k127_196575_1	870187.Thini_2256	3.406e-46	174.0	COG1309@1|root,COG1309@2|Bacteria,1RF0W@1224|Proteobacteria,1S8MA@1236|Gammaproteobacteria,462UF@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
SRR25158358_k127_196575_0	525904.Tter_2518	4.643e-89	303.0	COG4948@1|root,COG4948@2|Bacteria,2NR3V@2323|unclassified Bacteria	2|Bacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_1972859_2	335284.Pcryo_0617	2.09e-67	233.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,1T3BR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158358_k127_1972859_1	257310.BB0122	1.427e-75	274.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,3T8XM@506|Alcaligenaceae	28216|Betaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158358_k127_1972859_3	1121946.AUAX01000012_gene6617	2.028e-40	156.0	COG1309@1|root,COG1309@2|Bacteria,2GYI1@201174|Actinobacteria,4DH3X@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158358_k127_1972859_0	1283299.AUKG01000003_gene496	2.986e-176	564.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRWB@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_1972859_4	66874.JOFS01000041_gene6903	1.171e-06	54.0	COG2230@1|root,COG2230@2|Bacteria,2I82K@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31
SRR25158358_k127_1979842_1	1122939.ATUD01000009_gene3117	1.007e-78	269.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158358_k127_1979842_2	289376.THEYE_A1821	1.214e-06	55.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158358_k127_1979842_0	469383.Cwoe_1002	2.145e-230	722.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CRAM@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158358_k127_1981035_1	1206101.AZXC01000027_gene5563	3.514e-106	359.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158358_k127_1981035_0	1906.SFRA_16850	1.042e-112	372.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158358_k127_1981035_2	525904.Tter_2868	2.143e-35	147.0	COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158358_k127_1981035_3	1336235.JAEG01000016_gene4332	1.686e-09	65.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BCXZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HemolysinCabind,LTD
SRR25158358_k127_198274_3	525904.Tter_2778	4.674e-10	70.0	COG1409@1|root,COG3540@1|root,COG1409@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	LTD,Metallophos,Pur_ac_phosph_N
SRR25158358_k127_198274_1	1122609.AUGT01000002_gene3942	2.589e-31	129.0	2EF7F@1|root,3390F@2|Bacteria,2GZ58@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_198274_2	1122609.AUGT01000002_gene3940	6.549e-20	97.0	2E44S@1|root,32Z0U@2|Bacteria,2GXFW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_198274_0	1123024.AUII01000006_gene4638	7.111e-258	826.0	COG3696@1|root,COG3696@2|Bacteria,2H303@201174|Actinobacteria,4EF0N@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158358_k127_1982862_0	1380390.JIAT01000011_gene2565	0.0	1306.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158358_k127_1989866_2	1379698.RBG1_1C00001G0474	2.221e-35	147.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158358_k127_1989866_3	324602.Caur_3735	6.237e-29	127.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi,375RE@32061|Chloroflexia	32061|Chloroflexia	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158358_k127_1989866_4	1009370.ALO_02526	3.414e-28	120.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4H3V2@909932|Negativicutes	909932|Negativicutes	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158358_k127_1989866_0	929712.KI912613_gene3930	4.048e-155	511.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158358_k127_1989866_1	867903.ThesuDRAFT_01461	4.414e-59	211.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3WDH1@538999|Clostridiales incertae sedis	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158358_k127_1989866_5	1122939.ATUD01000004_gene3849	6.635e-09	61.0	COG0520@1|root,COG0520@2|Bacteria,2HP42@201174|Actinobacteria,4CQF7@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158358_k127_1992697_10	246196.MSMEI_0107	0.0001096	51.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,233R3@1762|Mycobacteriaceae	201174|Actinobacteria	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158358_k127_1992697_1	351607.Acel_1905	8.395e-135	461.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4ERVM@85013|Frankiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS
SRR25158358_k127_1992697_0	1231190.NA8A_19318	3.603e-163	527.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
SRR25158358_k127_1992697_4	405948.SACE_2451	2.28e-29	123.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4ECNY@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158358_k127_1992697_7	1380390.JIAT01000009_gene506	2.418e-23	104.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CTN1@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR25158358_k127_1992697_6	1380390.JIAT01000009_gene1867	1.812e-23	102.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CQCQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158358_k127_1992697_5	1077972.ARGLB_083_00490	6.252e-27	122.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
SRR25158358_k127_1992697_2	1463936.JOJI01000001_gene1989	1.365e-45	169.0	COG4405@1|root,COG4405@2|Bacteria,2IKQP@201174|Actinobacteria	201174|Actinobacteria	I	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158358_k127_1992697_3	40571.JOEA01000008_gene2550	8.299e-38	153.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4E0J5@85010|Pseudonocardiales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158358_k127_1992697_9	408672.NBCG_01694	1.369e-07	60.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria,4DRR1@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158358_k127_1992697_8	1283299.AUKG01000001_gene1333	4.741e-08	59.0	COG4454@1|root,COG4454@2|Bacteria,2HRFF@201174|Actinobacteria,4CTEA@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_1992704_3	479434.Sthe_0007	3.285e-26	112.0	COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi,27YV0@189775|Thermomicrobia	189775|Thermomicrobia	E	HMGL-like	-	-	4.1.3.46	ko:K18314	-	-	R10674	RC00502,RC01205	ko00000,ko01000	-	-	-	HMGL-like
SRR25158358_k127_1992704_0	469383.Cwoe_3975	2.896e-186	591.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CRFS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.20	ko:K07749,ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158358_k127_1992704_2	357808.RoseRS_0051	1.042e-46	178.0	COG1802@1|root,COG1802@2|Bacteria,2G8RX@200795|Chloroflexi,376HG@32061|Chloroflexia	32061|Chloroflexia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158358_k127_1992704_1	1229780.BN381_430003	9.334e-136	456.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158358_k127_1993647_1	1380390.JIAT01000002_gene5987	8.602e-36	151.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158358_k127_1993647_0	1380390.JIAT01000002_gene5986	3.299e-180	584.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CPR8@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158358_k127_200290_2	1380347.JNII01000012_gene2637	8.18e-84	295.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria	2|Bacteria	L	dead DEAH box helicase	suv3	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
SRR25158358_k127_200290_4	575540.Isop_1827	1.872e-42	174.0	COG0691@1|root,COG0691@2|Bacteria,2IZPN@203682|Planctomycetes	203682|Planctomycetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158358_k127_200290_5	390989.JOEG01000018_gene3673	1.733e-31	136.0	COG1670@1|root,COG3153@1|root,COG1670@2|Bacteria,COG3153@2|Bacteria,2IEHP@201174|Actinobacteria,4DCGX@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158358_k127_200290_3	28042.GU90_16815	6.542e-61	214.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E49V@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158358_k127_200290_0	266117.Rxyl_0112	2.43e-300	941.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CS94@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_200290_1	266117.Rxyl_0113	4.669e-108	359.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CSQX@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_202688_8	448385.sce8318	3.749e-05	48.0	COG0695@1|root,COG0695@2|Bacteria,1R0E1@1224|Proteobacteria,43CWH@68525|delta/epsilon subdivisions,2X84J@28221|Deltaproteobacteria,2Z2IF@29|Myxococcales	28221|Deltaproteobacteria	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158358_k127_202688_0	525904.Tter_0805	2.002e-141	463.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158358_k127_202688_7	1396.DJ87_510	1.164e-15	92.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	vpr	GO:0005575,GO:0005576	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,FlgD_ig,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5
SRR25158358_k127_202688_1	266117.Rxyl_0812	2.071e-96	325.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CPNE@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158358_k127_202688_3	1380390.JIAT01000016_gene5510	1.751e-38	152.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158358_k127_202688_6	1313172.YM304_08940	2.836e-20	98.0	COG1214@1|root,COG1214@2|Bacteria	2|Bacteria	O	tRNA threonylcarbamoyladenosine modification	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158358_k127_202688_4	469383.Cwoe_2896	1.498e-31	128.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158358_k127_202688_2	469383.Cwoe_2893	5.71e-68	238.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158358_k127_202688_5	1313172.YM304_38790	4.433e-22	104.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria	201174|Actinobacteria	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158358_k127_211200_0	1187851.A33M_4386	3.949e-211	677.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	MA20_01050	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
SRR25158358_k127_211200_4	1123023.JIAI01000007_gene1954	2.061e-62	226.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158358_k127_211200_6	1437448.AZRT01000160_gene1007	1.731e-11	67.0	COG4311@1|root,COG4311@2|Bacteria,1N8ED@1224|Proteobacteria,2UFIN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Sarcosine oxidase, delta subunit	soxD2	-	1.5.3.1,1.5.99.5	ko:K00304,ko:K22085	ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120	-	R00609,R00610	RC00060,RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
SRR25158358_k127_211200_1	1380391.JIAS01000011_gene5154	3.715e-208	678.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,2JQIX@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
SRR25158358_k127_211200_7	710685.MycrhN_4497	0.000227	53.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,235CE@1762|Mycobacteriaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158358_k127_211200_3	1123507.ATVQ01000001_gene1339	1.427e-151	499.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,1WA46@1268|Micrococcaceae	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158358_k127_211200_2	1121428.DESHY_40191___1	1.826e-201	647.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,2601Q@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158358_k127_211200_5	368408.Tpen_1466	7.072e-13	76.0	COG0589@1|root,arCOG02053@2157|Archaea,2XQTK@28889|Crenarchaeota	28889|Crenarchaeota	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158358_k127_219113_0	404589.Anae109_1089	2.567e-97	328.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2YTYS@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158358_k127_219113_2	1203568.HMPREF1484_00056	8.247e-06	51.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,4FD2P@85020|Dermabacteraceae	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158358_k127_219113_1	234621.RER_42950	1.651e-06	61.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria,4FZTD@85025|Nocardiaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_cc
SRR25158358_k127_221302_2	1380390.JIAT01000011_gene2751	1.545e-36	147.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CRYP@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158358_k127_221302_1	1283299.AUKG01000001_gene2831	3.365e-124	409.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CS29@84995|Rubrobacteria	84995|Rubrobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158358_k127_221302_0	1150864.MILUP08_43542	1.387e-139	453.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4D8GI@85008|Micromonosporales	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_229149_4	1380370.JIBA01000015_gene98	8.504e-91	317.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158358_k127_229149_0	1132441.KI519455_gene3061	5.762e-151	508.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,1WB46@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158358_k127_229149_5	312284.A20C1_08348	1.213e-76	287.0	COG1071@1|root,COG1071@2|Bacteria,2I3T8@201174|Actinobacteria,3UX94@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
SRR25158358_k127_229149_2	1380390.JIAT01000011_gene2306	1.505e-107	358.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CRBS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Transketolase central region	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158358_k127_229149_3	448385.sce7528	2.174e-92	326.0	COG0241@1|root,COG0645@1|root,COG0667@1|root,COG0241@2|Bacteria,COG0645@2|Bacteria,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	1.1.1.65,3.1.3.82,3.1.3.83,6.3.4.4	ko:K01939,ko:K03273,ko:K05275	ko00230,ko00250,ko00540,ko00750,ko01100,ko01120,map00230,map00250,map00540,map00750,map01100,map01120	M00049,M00064	R01135,R01708,R05647,R09771	RC00017,RC00116,RC00458,RC00459	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	AAA_33,Aldo_ket_red,Hydrolase_like
SRR25158358_k127_229149_1	1206101.AZXC01000010_gene24	2.634e-132	449.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158358_k127_230613_0	469383.Cwoe_2622	2.32e-98	331.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CS0G@84995|Rubrobacteria	84995|Rubrobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158358_k127_230613_5	469383.Cwoe_2623	7.721e-10	68.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	CBS,GGDEF,HisKA,SpoIIE
SRR25158358_k127_230613_1	1234364.AMSF01000016_gene1545	5.394e-89	307.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1X5GT@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158358_k127_230613_2	869210.Marky_0879	1.067e-76	271.0	COG1250@1|root,COG1250@2|Bacteria,1WIN8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158358_k127_230613_4	1380390.JIAT01000017_gene5271	2.084e-21	100.0	2B3SP@1|root,31WGA@2|Bacteria,2HQUY@201174|Actinobacteria,4CSMU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_230613_3	211114.JOEF01000004_gene6545	3.997e-28	115.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DXDP@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158358_k127_232632_0	1122138.AQUZ01000042_gene3415	8.854e-152	494.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158358_k127_232632_8	869210.Marky_0632	3.744e-07	58.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C
SRR25158358_k127_232632_9	1283299.AUKG01000002_gene4958	0.0009458	48.0	2AUU1@1|root,31KH5@2|Bacteria,2HPC3@201174|Actinobacteria,4CQQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_232632_1	1449346.JQMO01000003_gene6640	1.311e-119	404.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,2M1YW@2063|Kitasatospora	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158358_k127_232632_3	696369.KI912183_gene1973	4.712e-57	212.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,2673P@186807|Peptococcaceae	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158358_k127_232632_7	1283299.AUKG01000005_gene15	4.919e-13	78.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3
SRR25158358_k127_232632_5	1121272.KB903259_gene6524	6.865e-48	188.0	COG3247@1|root,COG3247@2|Bacteria,2ISIY@201174|Actinobacteria,4DMAA@85008|Micromonosporales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158358_k127_232632_4	1380390.JIAT01000009_gene1257	1.05e-53	197.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158358_k127_232632_2	1303518.CCALI_00131	1.695e-81	282.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_232632_6	639030.JHVA01000001_gene181	1.34e-21	105.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria,2JIHW@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_233164_3	1123242.JH636437_gene6034	1.787e-76	269.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_233164_4	1122927.KB895419_gene2277	1.08e-57	206.0	COG0454@1|root,COG0456@2|Bacteria,1VW2R@1239|Firmicutes,4I7IK@91061|Bacilli,26WWV@186822|Paenibacillaceae	91061|Bacilli	K	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158358_k127_233164_7	1116232.AHBF01000080_gene8453	8.654e-48	182.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_233164_0	2002.JOEQ01000011_gene3997	1.402e-220	698.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4EIS0@85012|Streptosporangiales	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158358_k127_233164_1	795797.C497_06389	3.265e-152	505.0	COG0145@1|root,arCOG01511@2157|Archaea,2XT1J@28890|Euryarchaeota,23SV5@183963|Halobacteria	183963|Halobacteria	E	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_233164_8	1122939.ATUD01000001_gene148	6.752e-47	171.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158358_k127_233164_2	555088.DealDRAFT_0546	2.244e-100	340.0	COG1680@1|root,COG1680@2|Bacteria,1V18R@1239|Firmicutes	1239|Firmicutes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158358_k127_233164_5	391600.ABRU01000056_gene579	6.224e-52	198.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,2U6YA@28211|Alphaproteobacteria,2KGUX@204458|Caulobacterales	204458|Caulobacterales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158358_k127_233164_9	1122611.KB903956_gene119	8.989e-27	116.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
SRR25158358_k127_233164_10	694431.DESACE_03770	2.768e-18	91.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2M76J@213113|Desulfurellales	28221|Deltaproteobacteria	O	CS domain	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158358_k127_233164_6	306281.AJLK01000102_gene3405	1.026e-48	178.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_233831_2	1283299.AUKG01000001_gene2309	2.235e-35	154.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CSES@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_233831_3	317619.ANKN01000111_gene1536	1.984e-25	113.0	COG0457@1|root,COG3914@1|root,COG4627@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,COG4627@2|Bacteria,1G0YS@1117|Cyanobacteria,1MNNH@1212|Prochloraceae	1117|Cyanobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158358_k127_233831_1	290397.Adeh_2080	5.591e-42	160.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria,2YZY7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158358_k127_233831_4	1192034.CAP_2515	7.094e-11	67.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,43A8B@68525|delta/epsilon subdivisions,2X2PT@28221|Deltaproteobacteria,2YW8X@29|Myxococcales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158358_k127_233831_0	1283299.AUKG01000002_gene3794	1.196e-76	277.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_23954_0	266117.Rxyl_2416	1.938e-184	587.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4CPWQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158358_k127_23954_2	690597.JH730982_gene1975	2.646e-52	187.0	COG2128@1|root,COG2128@2|Bacteria,1RD2I@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158358_k127_23954_1	47763.JNZA01000008_gene5255	3.624e-89	312.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158358_k127_23954_3	1521187.JPIM01000053_gene2953	1.489e-06	54.0	COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158358_k127_240215_1	290512.Paes_1870	6.938e-193	610.0	COG0372@1|root,COG0372@2|Bacteria,1FD5Z@1090|Chlorobi	1090|Chlorobi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158358_k127_240215_4	1121405.dsmv_2338	6.911e-17	84.0	COG1146@1|root,COG1146@2|Bacteria,1N0QV@1224|Proteobacteria,42U2Z@68525|delta/epsilon subdivisions,2WR58@28221|Deltaproteobacteria,2MM2N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
SRR25158358_k127_240215_2	765912.Thimo_0250	9.824e-136	442.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1WXU8@135613|Chromatiales	135613|Chromatiales	C	oxidoreductase, alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N,Transketolase_C
SRR25158358_k127_240215_0	290318.Cvib_0843	2.572e-253	797.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
SRR25158358_k127_240215_3	237368.SCABRO_01876	9.219e-54	202.0	COG1908@1|root,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	hdrG	-	-	-	-	-	-	-	-	-	-	-	FlpD
SRR25158358_k127_244657_0	1463887.KL589982_gene4680	5.835e-41	168.0	COG0457@1|root,COG0457@2|Bacteria,2GJD3@201174|Actinobacteria	201174|Actinobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SRR25158358_k127_258724_1	469383.Cwoe_3771	9.877e-87	302.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CSTK@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158358_k127_258724_0	469383.Cwoe_3772	3.205e-99	337.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158358_k127_264776_2	593907.Celgi_0066	9.815e-50	194.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4F2AP@85016|Cellulomonadaceae	201174|Actinobacteria	S	TIGRFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158358_k127_264776_0	1380390.JIAT01000017_gene5272	2.918e-124	422.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CU6W@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
SRR25158358_k127_264776_4	216594.MMAR_5256	8.732e-20	93.0	COG2128@1|root,COG2128@2|Bacteria,2ICVV@201174|Actinobacteria,236U4@1762|Mycobacteriaceae	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158358_k127_264776_9	861299.J421_4028	8.122e-12	72.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158358_k127_264776_6	1299327.I546_5685	6.733e-13	75.0	2EG5E@1|root,339XC@2|Bacteria,2IS3W@201174|Actinobacteria,23EZK@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_264776_5	225937.HP15_3126	2.151e-13	78.0	COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,1SR7U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158358_k127_264776_1	1169161.KB897729_gene1305	7.075e-114	380.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria	201174|Actinobacteria	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158358_k127_264776_7	318424.EU78_17755	1.279e-12	74.0	COG2905@1|root,COG2905@2|Bacteria,2I3M3@201174|Actinobacteria,23F9T@1762|Mycobacteriaceae	201174|Actinobacteria	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158358_k127_264776_8	281090.Lxx24060	4.853e-12	74.0	2EYX9@1|root,33T02@2|Bacteria,2I55V@201174|Actinobacteria	201174|Actinobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR25158358_k127_264776_3	1116232.AHBF01000234_gene6221	4.527e-23	104.0	2EYX9@1|root,33S42@2|Bacteria,2IABS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR25158358_k127_26641_3	323259.Mhun_2374	8.844e-26	119.0	COG0500@1|root,arCOG01789@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158358_k127_26641_0	383372.Rcas_3084	1.233e-102	355.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158358_k127_26641_2	469383.Cwoe_1589	6.374e-29	120.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_26641_1	1283299.AUKG01000001_gene2309	4.969e-40	162.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CSES@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_272273_4	161528.ED21_28888	8.194e-10	63.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158358_k127_272273_0	469383.Cwoe_0824	1.677e-154	500.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CPN1@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158358_k127_272273_2	1380390.JIAT01000009_gene1204	6.237e-62	228.0	COG3336@1|root,COG3336@2|Bacteria,2HPY7@201174|Actinobacteria,4CRDE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158358_k127_272273_1	180281.CPCC7001_2321	1.336e-81	282.0	COG0150@1|root,COG0150@2|Bacteria,1G1WY@1117|Cyanobacteria,22SC8@167375|Cyanobium	1117|Cyanobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158358_k127_272273_3	1120936.KB907214_gene4270	4.012e-44	183.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4EITU@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158358_k127_27294_3	1283299.AUKG01000001_gene2262	1.139e-62	222.0	COG2227@1|root,COG2227@2|Bacteria,2GPBV@201174|Actinobacteria,4CTKC@84995|Rubrobacteria	84995|Rubrobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158358_k127_27294_5	469383.Cwoe_5500	3.634e-59	217.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4CQZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158358_k127_27294_6	1283299.AUKG01000001_gene2267	1.553e-55	213.0	COG2244@1|root,COG2244@2|Bacteria,2HR10@201174|Actinobacteria,4CSV4@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158358_k127_27294_0	1283299.AUKG01000001_gene2266	1.397e-101	359.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_2,Glyco_transf_4,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158358_k127_27294_1	1121924.ATWH01000005_gene2823	9.629e-98	336.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4FMZB@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_27294_11	1521187.JPIM01000004_gene3091	0.0003476	48.0	2EU3R@1|root,33MKI@2|Bacteria,2G9PI@200795|Chloroflexi,375XX@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_27294_2	867845.KI911784_gene1734	1.673e-86	301.0	COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158358_k127_27294_4	234267.Acid_6233	4.334e-60	225.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158358_k127_27294_10	1280671.AUJH01000008_gene293	3.373e-05	57.0	29U10@1|root,30FA5@2|Bacteria,1UDQX@1239|Firmicutes,25IHZ@186801|Clostridia,4BW63@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_27294_8	867845.KI911784_gene136	7.011e-45	176.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_27294_7	1382356.JQMP01000003_gene1927	4.15e-47	183.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_27294_9	754476.Q7A_1436	5.898e-17	95.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,4612P@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferases group 1	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158358_k127_287011_1	713586.KB900536_gene40	3.344e-214	675.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase family 65, central catalytic	ycjT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64,3.2.1.28,5.4.2.6	ko:K01194,ko:K01838,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SRR25158358_k127_287011_0	1122939.ATUD01000004_gene3937	2.919e-216	693.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4CPMZ@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158358_k127_287011_2	929712.KI912613_gene3945	5.821e-35	137.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CPMY@84995|Rubrobacteria	84995|Rubrobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158358_k127_287869_0	266117.Rxyl_2032	1.802e-70	258.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CPCG@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158358_k127_287869_1	479434.Sthe_2813	4.768e-70	248.0	COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_287869_2	309801.trd_A0776	7.757e-53	194.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	2|Bacteria	C	2Fe-2S -binding domain protein	coxS	-	1.2.5.3,1.3.99.16,1.5.99.4	ko:K03518,ko:K07302,ko:K19819	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158358_k127_287869_3	365528.KB891259_gene483	1.581e-17	91.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EU5S@85013|Frankiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3,1.5.99.4	ko:K03520,ko:K19820	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_297639_0	469383.Cwoe_4727	9.045e-122	402.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CRSZ@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158358_k127_297639_5	218140.BPSY_1710	6.334e-12	72.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CZXD@85004|Bifidobacteriales	201174|Actinobacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158358_k127_297639_1	710111.FraQA3DRAFT_4615	2.239e-119	387.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4EUJK@85013|Frankiales	201174|Actinobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158358_k127_297639_3	266779.Meso_2458	6.529e-86	294.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
SRR25158358_k127_297639_2	1054860.KB913030_gene3436	1.007e-106	354.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158358_k127_297639_4	479434.Sthe_1229	2.664e-51	186.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158358_k127_300620_7	1380390.JIAT01000011_gene2394	9.332e-45	171.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4CPZC@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
SRR25158358_k127_300620_5	1184609.KILIM_089_00130	8.512e-65	237.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158358_k127_300620_2	316055.RPE_3782	2.777e-84	287.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TSE7@28211|Alphaproteobacteria,3JRVG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	amino acid	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158358_k127_300620_3	1121106.JQKB01000020_gene1996	2.089e-80	274.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,2JW92@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158358_k127_300620_1	1120936.KB907208_gene1216	4.901e-90	308.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4EIQD@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158358_k127_300620_4	1380394.JADL01000002_gene1158	1.557e-70	262.0	COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2TUBF@28211|Alphaproteobacteria,2JUXE@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158358_k127_300620_6	469383.Cwoe_0432	2.189e-55	210.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4CQI7@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158358_k127_300620_8	1245469.S58_21230	2.317e-22	105.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TU6Q@28211|Alphaproteobacteria,3JUQS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158358_k127_300620_0	525904.Tter_2623	2.274e-255	803.0	COG1060@1|root,COG1060@2|Bacteria,2NP8W@2323|unclassified Bacteria	2|Bacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	fbiC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,Radical_SAM
SRR25158358_k127_307751_3	1121272.KB903291_gene3433	7e-43	161.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD
SRR25158358_k127_307751_2	1122138.AQUZ01000039_gene8019	3.014e-64	239.0	COG0842@1|root,COG0842@2|Bacteria,2I8FD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_307751_1	1122138.AQUZ01000039_gene8020	6.936e-71	248.0	COG0842@1|root,COG0842@2|Bacteria,2HDDD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_307751_0	1122138.AQUZ01000039_gene8021	2.866e-139	451.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4DNSV@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_307751_4	1380370.JIBA01000013_gene1586	7.019e-17	93.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FG5U@85021|Intrasporangiaceae	201174|Actinobacteria	E	branched-chain amino acid	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158358_k127_310272_1	635013.TherJR_1640	6.139e-69	249.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,260EB@186807|Peptococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158358_k127_310272_0	1122223.KB890688_gene1465	2.31e-75	260.0	COG0428@1|root,COG0428@2|Bacteria,1WIUI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
SRR25158358_k127_310272_2	319795.Dgeo_2157	5.633e-15	86.0	COG1295@1|root,COG1295@2|Bacteria,1WMJT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158358_k127_310272_3	351607.Acel_1395	3.149e-05	46.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria,4EW9T@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_310669_3	469383.Cwoe_1378	2.13e-49	192.0	COG3858@1|root,COG3858@2|Bacteria,2HZ7I@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158358_k127_310669_6	485913.Krac_12349	1.503e-36	161.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi	200795|Chloroflexi	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Polysacc_deac_1
SRR25158358_k127_310669_2	469383.Cwoe_1375	1.215e-126	422.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4CTQF@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 21	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	-
SRR25158358_k127_310669_7	446462.Amir_4586	3.583e-18	99.0	COG1670@1|root,COG1670@2|Bacteria,2IIWF@201174|Actinobacteria,4E41X@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128,2.3.1.82	ko:K00663,ko:K03790	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158358_k127_310669_5	1380390.JIAT01000009_gene406	8.478e-44	171.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4CQ0Q@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_310669_4	999541.bgla_1g11780	1.009e-48	184.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,1K0M9@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	Drug metabolite transporter (DMT) superfamily	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_310669_1	215803.DB30_0113	1.075e-144	490.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2YUAS@29|Myxococcales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158358_k127_310669_0	469383.Cwoe_0822	1.467e-201	644.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158358_k127_312547_5	945713.IALB_2285	4.308e-53	192.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158358_k127_312547_6	1298863.AUEP01000011_gene657	1.592e-16	83.0	COG1225@1|root,COG3339@1|root,COG1225@2|Bacteria,COG3339@2|Bacteria,2IR8D@201174|Actinobacteria,4DSW6@85009|Propionibacteriales	201174|Actinobacteria	O	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_312547_4	1380356.JNIK01000015_gene2305	8.972e-59	214.0	COG3217@1|root,COG3217@2|Bacteria,2HU2E@201174|Actinobacteria,4EWKT@85013|Frankiales	201174|Actinobacteria	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158358_k127_312547_1	886379.AEWI01000002_gene491	2.426e-86	290.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,3XKG1@558415|Marinilabiliaceae	976|Bacteroidetes	L	Uracil DNA glycosylase superfamily	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158358_k127_312547_0	1313172.YM304_12080	4.113e-148	481.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158358_k127_312547_2	220341.16503194	1.452e-84	288.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,3ZJX4@590|Salmonella	1236|Gammaproteobacteria	E	AAA domain	yecC	GO:0000099,GO:0000101,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363,GO:1901682,GO:1902475,GO:1903825,GO:1905039	3.6.3.21	ko:K02028,ko:K02029,ko:K10004,ko:K10010,ko:K10038	ko02010,ko02020,map02010,map02020	M00227,M00230,M00234,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.19,3.A.1.3.2,3.A.1.3.4	-	-	ABC_tran
SRR25158358_k127_312547_3	1122609.AUGT01000002_gene3997	9.065e-80	270.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4DQAE@85009|Propionibacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	glnP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
SRR25158358_k127_319083_5	35754.JNYJ01000043_gene4574	1.469e-20	97.0	COG1051@1|root,COG1051@2|Bacteria,2IQ38@201174|Actinobacteria,4DE4Y@85008|Micromonosporales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158358_k127_319083_4	390989.JOEG01000004_gene3854	1.619e-33	133.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4DE4S@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158358_k127_319083_0	525904.Tter_0977	2.196e-268	858.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158358_k127_319083_1	469383.Cwoe_1837	3.149e-118	389.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158358_k127_319083_2	1246995.AFR_27055	9.41e-118	392.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DHDF@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158358_k127_334003_3	309801.trd_A0882	3.584e-22	100.0	COG0671@1|root,COG0671@2|Bacteria,2GB9M@200795|Chloroflexi,27YCA@189775|Thermomicrobia	189775|Thermomicrobia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158358_k127_334003_1	469383.Cwoe_1913	5.29e-30	135.0	COG0392@1|root,COG0392@2|Bacteria,2HQ3T@201174|Actinobacteria,4CRKA@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158358_k127_334003_2	1313172.YM304_11230	1.667e-25	121.0	COG2845@1|root,COG2845@2|Bacteria,2GU62@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
SRR25158358_k127_334003_0	479433.Caci_1300	1.754e-146	477.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria	201174|Actinobacteria	M	Membrane bound O-acyl transferase MBOAT family protein	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
SRR25158358_k127_334003_5	1410618.JNKI01000008_gene569	4.941e-11	71.0	COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4H2KI@909932|Negativicutes	909932|Negativicutes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158358_k127_334003_4	743718.Isova_0630	3.318e-11	74.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4F3VN@85017|Promicromonosporaceae	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158358_k127_3432_0	671143.DAMO_2354	2.265e-83	287.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SRR25158358_k127_3432_1	543632.JOJL01000035_gene5070	5.978e-29	124.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158358_k127_346452_4	469383.Cwoe_1955	1.235e-53	193.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CSBR@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158358_k127_346452_0	1313172.YM304_06050	4.295e-160	517.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CMTT@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Fumarate hydratase class II	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158358_k127_346452_1	751945.Theos_2092	1.157e-91	310.0	COG0320@1|root,COG0320@2|Bacteria,1WIE7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158358_k127_346452_5	671143.DAMO_1594	1.996e-48	181.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158358_k127_346452_3	298655.KI912266_gene277	5.472e-56	214.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4EWG8@85013|Frankiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158358_k127_346452_2	1382359.JIAL01000001_gene1185	1.969e-67	238.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158358_k127_349396_1	1283299.AUKG01000002_gene4621	1.858e-75	263.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CPNI@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158358_k127_349396_2	1394178.AWOO02000032_gene4875	2.021e-61	226.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4EG2K@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158358_k127_349396_3	292459.STH1211	1.3e-54	209.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158358_k127_349396_4	1452535.JARD01000008_gene1580	4.684e-14	86.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4FNQI@85023|Microbacteriaceae	201174|Actinobacteria	M	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158358_k127_349396_0	266117.Rxyl_1489	8.26e-138	447.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158358_k127_349396_5	1123229.AUBC01000010_gene3413	0.0002425	44.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,3JRGH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	glycine cleavage system	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158358_k127_35011_5	1283299.AUKG01000002_gene5058	5.172e-29	124.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4CQ1P@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158358_k127_35011_2	1128421.JAGA01000002_gene393	6.608e-69	244.0	COG2313@1|root,COG2313@2|Bacteria,2NQKQ@2323|unclassified Bacteria	2|Bacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158358_k127_35011_1	1283299.AUKG01000001_gene3048	6.009e-98	340.0	COG4948@1|root,COG4948@2|Bacteria,2I7AE@201174|Actinobacteria,4CPIJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_35011_4	379066.GAU_3531	1.076e-31	131.0	COG0775@1|root,COG0775@2|Bacteria,1ZUX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphorylase superfamily	-	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158358_k127_35011_3	479434.Sthe_3331	6.005e-40	153.0	2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158358_k127_35011_0	1303518.CCALI_00290	2.355e-269	841.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158358_k127_352239_2	1089551.KE386572_gene1045	1.187e-51	186.0	COG2867@1|root,COG2867@2|Bacteria,1QW7G@1224|Proteobacteria,2TWR8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	QU41_28450	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158358_k127_352239_0	1057002.KB905370_gene4455	1.29e-218	693.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,4BBS0@82115|Rhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158358_k127_352239_3	331869.BAL199_26202	3.91e-38	150.0	2ER8M@1|root,33IU6@2|Bacteria,1NBUC@1224|Proteobacteria,2UFGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_352239_1	1121033.AUCF01000012_gene943	3.873e-79	270.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2VF24@28211|Alphaproteobacteria,2JVZ0@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_365317_0	266117.Rxyl_1205	0.0	1615.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4CRPX@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SRR25158358_k127_365317_1	518766.Rmar_2293	4.207e-59	214.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1FJQM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Hemerythrin HHE cation binding domain	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SRR25158358_k127_365317_2	1123065.ATWL01000012_gene2670	3.488e-05	50.0	2C4YV@1|root,2ZPNJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158358_k127_367294_4	1122939.ATUD01000025_gene2542	1.97e-05	50.0	2A7CM@1|root,30W9I@2|Bacteria,2IJCC@201174|Actinobacteria	201174|Actinobacteria	S	Camelysin metallo-endopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M73
SRR25158358_k127_367294_2	1410617.JHXH01000001_gene726	9.113e-13	76.0	COG0681@1|root,COG0681@2|Bacteria,1TTI0@1239|Firmicutes,259ND@186801|Clostridia,3WJID@541000|Ruminococcaceae	186801|Clostridia	U	Peptidase S24-like	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158358_k127_367294_1	469383.Cwoe_1802	1.088e-89	309.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158358_k127_367294_0	1379698.RBG1_1C00001G1217	4.301e-142	471.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2NP05@2323|unclassified Bacteria	2|Bacteria	H	Methylenetetrahydrofolate reductase	yitJ	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
SRR25158358_k127_367294_3	485918.Cpin_3805	8.969e-07	51.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,DUF4849
SRR25158358_k127_375613_2	1445613.JALM01000003_gene4963	9.054e-82	282.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4DZSC@85010|Pseudonocardiales	201174|Actinobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158358_k127_375613_0	471852.Tcur_2157	4.407e-125	412.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4EI3P@85012|Streptosporangiales	201174|Actinobacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
SRR25158358_k127_375613_7	300852.55772941	5.655e-21	100.0	COG1438@1|root,COG1438@2|Bacteria,1WK2G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158358_k127_375613_1	640132.Srot_0982	9.303e-100	343.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria	201174|Actinobacteria	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158358_k127_375613_6	31964.CMS1233	4.527e-24	115.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4FK9H@85023|Microbacteriaceae	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158358_k127_375613_3	767029.HMPREF9154_2030	1.859e-81	286.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4DN1T@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158358_k127_375613_4	1123240.ATVO01000005_gene1832	1.33e-67	243.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2K2G3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
SRR25158358_k127_375613_5	765420.OSCT_0551	4.221e-38	147.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,37589@32061|Chloroflexia	32061|Chloroflexia	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158358_k127_376103_4	1142394.PSMK_22760	4.16e-47	183.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_376103_3	2074.JNYD01000021_gene865	2.571e-50	187.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria,4EAS4@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_376103_2	1220534.B655_1978	3.05e-89	310.0	COG0025@1|root,arCOG01961@2157|Archaea,2Y0UK@28890|Euryarchaeota	28890|Euryarchaeota	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158358_k127_376103_5	258052.JNYV01000006_gene2659	1.952e-35	139.0	2AY0M@1|root,31Q26@2|Bacteria,2IMBI@201174|Actinobacteria,2M3SS@2063|Kitasatospora	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158358_k127_376103_0	1429046.RR21198_4164	1.078e-124	410.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria,4FTY3@85025|Nocardiaceae	201174|Actinobacteria	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158358_k127_376103_1	1184609.KILIM_102_00050	1.334e-116	380.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158358_k127_387026_3	867903.ThesuDRAFT_01328	1.396e-14	79.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
SRR25158358_k127_387026_0	1303518.CCALI_01986	3.739e-63	241.0	COG3605@1|root,COG3920@1|root,COG3605@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1	ko:K00936,ko:K01719,ko:K01768,ko:K02030,ko:K02584,ko:K10441,ko:K13924,ko:K20962	ko00230,ko00860,ko01100,ko01110,ko01120,ko02010,ko02020,ko02025,ko02030,ko04113,ko04213,ko05111,map00230,map00860,map01100,map01110,map01120,map02010,map02020,map02025,map02030,map04113,map04213,map05111	M00121,M00212,M00236,M00506,M00695,M00839	R00089,R00434,R03165	RC00295,RC01861	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035,ko03000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.3	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12,TPR_8
SRR25158358_k127_387026_1	926560.KE387027_gene420	4.187e-48	177.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158358_k127_387026_2	1537715.JQFJ01000002_gene1616	1.18e-27	116.0	COG0346@1|root,COG0346@2|Bacteria,1RF1Z@1224|Proteobacteria,2U7I9@28211|Alphaproteobacteria,2K6PI@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_389298_0	1168034.FH5T_19395	1.033e-52	196.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,2FQJ2@200643|Bacteroidia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158358_k127_389298_1	502025.Hoch_4801	1.367e-52	198.0	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,43ADC@68525|delta/epsilon subdivisions,2X5T8@28221|Deltaproteobacteria,2Z38R@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	lytT	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
SRR25158358_k127_389298_2	452637.Oter_0068	6.999e-15	78.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
SRR25158358_k127_406934_2	1210884.HG799462_gene9132	2.608e-19	91.0	COG2608@1|root,COG2608@2|Bacteria,2J4PH@203682|Planctomycetes	203682|Planctomycetes	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_406934_1	644966.Tmar_1605	9.712e-25	113.0	COG0640@1|root,COG0640@2|Bacteria,1V859@1239|Firmicutes,25BD1@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158358_k127_406934_0	1299327.I546_5578	6.419e-37	149.0	COG1249@1|root,COG1249@2|Bacteria,2I24Y@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	MerB
SRR25158358_k127_407707_0	1094980.Mpsy_1273	1.812e-119	392.0	COG3875@1|root,arCOG02046@2157|Archaea,2XVDD@28890|Euryarchaeota,2N9Q8@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158358_k127_407707_2	388401.RB2150_18207	1.09e-06	59.0	COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria,2U4IR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_407707_1	1146883.BLASA_1459	1.418e-12	80.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRR25158358_k127_408082_2	1205680.CAKO01000040_gene1125	2.941e-10	66.0	COG5031@1|root,COG5031@2|Bacteria,1REM1@1224|Proteobacteria,2U762@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_408082_1	395961.Cyan7425_0315	1.141e-28	127.0	COG5031@1|root,COG5031@2|Bacteria,1GAK8@1117|Cyanobacteria	1117|Cyanobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_408082_0	296591.Bpro_1406	0.0	1529.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VPH8@28216|Betaproteobacteria,4AF3Y@80864|Comamonadaceae	28216|Betaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158358_k127_410727_2	1417296.U879_16895	1.669e-05	57.0	COG3664@1|root,COG3664@2|Bacteria,1R9BQ@1224|Proteobacteria,2U0MR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_410727_1	446470.Snas_1115	1.4e-16	93.0	COG1503@1|root,COG1503@2|Bacteria,2IJI5@201174|Actinobacteria,4EYIQ@85014|Glycomycetales	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_410727_0	1287116.X734_19005	1.905e-43	162.0	COG0395@1|root,COG0395@2|Bacteria,1MXTE@1224|Proteobacteria,2TSM4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K17323	ko02010,map02010	M00207,M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.35	-	-	BPD_transp_1
SRR25158358_k127_410806_6	709986.Deima_2799	0.0007654	48.0	COG2074@1|root,COG2074@2|Bacteria,1WI2U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	2-phosphoglycerate kinase	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	ATP-cone
SRR25158358_k127_410806_1	266117.Rxyl_1657	1.012e-104	367.0	COG2403@1|root,COG2403@2|Bacteria,2H3G5@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	-
SRR25158358_k127_410806_2	42256.RradSPS_1600	2.841e-96	330.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158358_k127_410806_5	926569.ANT_18270	1.502e-28	120.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
SRR25158358_k127_410806_4	696281.Desru_1270	4.436e-39	155.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158358_k127_410806_3	929712.KI912613_gene4754	3.26e-50	195.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,4CPU0@84995|Rubrobacteria	84995|Rubrobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158358_k127_410806_0	309801.trd_1222	1.173e-138	459.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,27Y17@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158358_k127_417669_2	469383.Cwoe_3491	1.423e-40	156.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4CQ8I@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158358_k127_417669_5	1122939.ATUD01000008_gene2537	1.53e-10	69.0	2AUU1@1|root,31KH5@2|Bacteria,2HPC3@201174|Actinobacteria,4CQQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_417669_0	1449347.JQLN01000001_gene750	5.491e-196	647.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,2M2GY@2063|Kitasatospora	201174|Actinobacteria	GJM	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158358_k127_417669_3	1120917.AQXM01000063_gene2090	2.475e-23	110.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,1W7EB@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158358_k127_417669_6	1111069.TCCBUS3UF1_19590	1.028e-08	64.0	COG1371@1|root,COG1371@2|Bacteria,1WJYM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158358_k127_417669_1	246197.MXAN_5426	1.296e-162	525.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YZRQ@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158358_k127_417669_4	1348663.KCH_50890	8.809e-18	83.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,2M1SN@2063|Kitasatospora	201174|Actinobacteria	O	Tetratricopeptide repeat	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158358_k127_427357_0	469371.Tbis_1355	1.643e-310	978.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4E0DG@85010|Pseudonocardiales	201174|Actinobacteria	EF	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158358_k127_433839_0	1283299.AUKG01000004_gene1030	1.676e-199	636.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158358_k127_433839_1	1283299.AUKG01000004_gene1029	1.251e-198	636.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPT4@84995|Rubrobacteria	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158358_k127_433839_2	1386089.N865_18985	1.284e-108	369.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria	201174|Actinobacteria	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158358_k127_449702_3	526227.Mesil_0245	1.117e-84	284.0	COG2223@1|root,COG2223@2|Bacteria,1WJ7D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRR25158358_k127_449702_9	469383.Cwoe_1510	5.031e-11	74.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3
SRR25158358_k127_449702_8	671143.DAMO_0779	8.789e-24	113.0	COG2010@1|root,COG2010@2|Bacteria,2NR8D@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158358_k127_449702_2	671143.DAMO_0778	1.489e-140	448.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SRR25158358_k127_449702_0	290397.Adeh_2170	0.0	1206.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,42P6X@68525|delta/epsilon subdivisions,2WK8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
SRR25158358_k127_449702_1	671143.DAMO_0776	5.204e-222	716.0	COG1140@1|root,COG1140@2|Bacteria,2NQZJ@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
SRR25158358_k127_449702_7	323097.Nham_3446	4.745e-24	111.0	COG2180@1|root,COG2180@2|Bacteria,1NBVT@1224|Proteobacteria	1224|Proteobacteria	C	nitrate reductase molybdenum cofactor assembly chaperone	-	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
SRR25158358_k127_449702_4	323098.Nwi_0778	3.315e-75	258.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2TTDB@28211|Alphaproteobacteria,3JWMR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
SRR25158358_k127_449702_5	1521187.JPIM01000059_gene2878	2.736e-71	262.0	COG0523@1|root,COG0523@2|Bacteria,2G8UM@200795|Chloroflexi,374WP@32061|Chloroflexia	32061|Chloroflexia	S	cobalamin synthesis CobW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
SRR25158358_k127_449702_6	1121445.ATUZ01000017_gene1988	5.589e-66	235.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2M9K5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158358_k127_459159_6	471852.Tcur_2377	2.451e-29	123.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4EGJE@85012|Streptosporangiales	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158358_k127_459159_0	749414.SBI_00351	5.016e-275	854.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158358_k127_459159_1	351607.Acel_1820	6.034e-154	493.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4ES6V@85013|Frankiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase (Decarboxylating)	gnd2	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1122	6PGD,NAD_binding_2
SRR25158358_k127_459159_3	1121877.JQKF01000003_gene1583	6.143e-72	248.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158358_k127_459159_5	469383.Cwoe_2518	2.856e-50	192.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_459159_4	1343740.M271_11730	3.306e-59	224.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph1	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase_like
SRR25158358_k127_459159_2	794903.OPIT5_19945	3.101e-93	327.0	COG0111@1|root,COG0111@2|Bacteria,46XXJ@74201|Verrucomicrobia,3K8JZ@414999|Opitutae	414999|Opitutae	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_466677_1	1123389.ATXJ01000004_gene1212	2.767e-65	230.0	COG0235@1|root,COG0235@2|Bacteria,1WID4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158358_k127_466677_2	1283299.AUKG01000001_gene2479	3.125e-19	99.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
SRR25158358_k127_466677_0	1476583.DEIPH_ctg046orf0021	9.821e-126	414.0	COG2223@1|root,COG2223@2|Bacteria,1WJJV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRR25158358_k127_46972_11	3827.XP_004509890.1	1.253e-06	61.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MGX@33090|Viridiplantae,3GE77@35493|Streptophyta,4JFY3@91835|fabids	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241	-	ko:K07761,ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
SRR25158358_k127_46972_3	469383.Cwoe_3188	1.576e-114	380.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria,4CRZY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_46972_6	469383.Cwoe_5036	4.556e-62	218.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158358_k127_46972_0	1380390.JIAT01000009_gene2051	0.0	1668.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4CPU9@84995|Rubrobacteria	84995|Rubrobacteria	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158358_k127_46972_1	1381123.AYOD01000012_gene3000	6.02e-130	433.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,43NJ8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
SRR25158358_k127_46972_8	324602.Caur_2685	2.151e-42	166.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi,375F0@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158358_k127_46972_7	469383.Cwoe_5804	1.398e-56	209.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4CT3E@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158358_k127_46972_9	929712.KI912613_gene2829	1.037e-14	86.0	2ATZV@1|root,31JJQ@2|Bacteria,2HNRB@201174|Actinobacteria,4CPYQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_46972_10	1122214.AQWH01000020_gene3296	1.348e-11	75.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,2UDER@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_46972_4	1380390.JIAT01000009_gene416	1.124e-106	354.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CPVA@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158358_k127_46972_2	469383.Cwoe_4667	1.318e-128	429.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CRHI@84995|Rubrobacteria	84995|Rubrobacteria	D	Tubulin/FtsZ family, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C,Tubulin
SRR25158358_k127_46972_5	648996.Theam_0649	1.332e-68	254.0	COG0405@1|root,COG0405@2|Bacteria,2G3M5@200783|Aquificae	200783|Aquificae	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158358_k127_471959_1	644966.Tmar_0617	1.507e-52	187.0	COG0235@1|root,COG0235@2|Bacteria,1UQ50@1239|Firmicutes	1239|Firmicutes	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158358_k127_471959_3	479434.Sthe_2034	2.687e-16	91.0	COG4243@1|root,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,27YHV@189775|Thermomicrobia	189775|Thermomicrobia	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158358_k127_471959_2	1380390.JIAT01000009_gene1332	5.294e-31	134.0	COG1651@1|root,COG1651@2|Bacteria,2HP5M@201174|Actinobacteria,4CQHM@84995|Rubrobacteria	84995|Rubrobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158358_k127_471959_0	1122939.ATUD01000001_gene812	2.253e-97	341.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4CU6T@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158358_k127_476456_4	1287116.X734_19005	1.432e-33	133.0	COG0395@1|root,COG0395@2|Bacteria,1MXTE@1224|Proteobacteria,2TSM4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K17323	ko02010,map02010	M00207,M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.35	-	-	BPD_transp_1
SRR25158358_k127_476456_3	1040986.ATYO01000011_gene5514	1.193e-33	134.0	COG0395@1|root,COG0395@2|Bacteria,1N0IZ@1224|Proteobacteria,2VEX4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158358_k127_476456_0	1038859.AXAU01000057_gene188	2.545e-176	573.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158358_k127_476456_1	518766.Rmar_0499	6.208e-82	294.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158358_k127_476456_2	357808.RoseRS_3093	4.744e-69	250.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,376B5@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158358_k127_479727_0	1380390.JIAT01000010_gene4114	8.197e-98	331.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CU29@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_479727_5	298655.KI912267_gene7331	3.213e-05	56.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_479727_3	1380356.JNIK01000017_gene2921	4.207e-32	130.0	2DK6R@1|root,32UEG@2|Bacteria,2INPY@201174|Actinobacteria,4EW57@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158358_k127_479727_4	1123389.ATXJ01000010_gene1803	5.508e-19	89.0	COG2154@1|root,COG2154@2|Bacteria,1WKD8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158358_k127_479727_2	751945.Theos_1761	7.914e-45	175.0	COG0558@1|root,COG0558@2|Bacteria,1WIUS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SRR25158358_k127_479727_1	709986.Deima_3003	2.414e-79	284.0	COG1028@1|root,COG1028@2|Bacteria,1WIJC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_479727_6	1380390.JIAT01000013_gene209	0.0009726	42.0	COG1028@1|root,COG1028@2|Bacteria,2GXKF@201174|Actinobacteria,4CS3Z@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_482058_2	452652.KSE_35330	4.298e-15	83.0	COG2365@1|root,COG2365@2|Bacteria,2IR8R@201174|Actinobacteria,2M4WD@2063|Kitasatospora	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
SRR25158358_k127_482058_1	1122939.ATUD01000005_gene2760	4.829e-45	180.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CQW4@84995|Rubrobacteria	84995|Rubrobacteria	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158358_k127_482058_0	330214.NIDE0596	1.127e-45	181.0	COG0253@1|root,COG0253@2|Bacteria,3J0JV@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158358_k127_482058_3	485918.Cpin_5960	1.426e-07	52.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158358_k127_488692_2	35754.JNYJ01000060_gene2493	4.627e-59	220.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158358_k127_488692_4	526218.Sterm_1184	5.771e-17	91.0	COG1051@1|root,COG1051@2|Bacteria,37ASE@32066|Fusobacteria	32066|Fusobacteria	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158358_k127_488692_3	929712.KI912613_gene3614	5.579e-41	170.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158358_k127_488692_0	211114.JOEF01000004_gene6665	7.217e-101	347.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4DXMT@85010|Pseudonocardiales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158358_k127_488692_1	1122939.ATUD01000005_gene2765	4.169e-72	253.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CP61@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158358_k127_489675_1	1380390.JIAT01000010_gene4759	1.48e-102	345.0	COG0568@1|root,COG0568@2|Bacteria,2HGMA@201174|Actinobacteria,4CR9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 factor, region 1.2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_489675_2	414996.IL38_23285	9.633e-21	98.0	COG3324@1|root,COG3324@2|Bacteria,2GPAS@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158358_k127_489675_0	1283299.AUKG01000002_gene4341	0.0	1257.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158358_k127_499456_0	768679.TTX_1889	3.775e-68	246.0	COG0148@1|root,arCOG01169@2157|Archaea,2XPZ6@28889|Crenarchaeota	28889|Crenarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158358_k127_499456_1	374847.Kcr_0796	3.556e-56	220.0	COG2423@1|root,arCOG01035@2157|Archaea	2157|Archaea	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	ala	-	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158358_k127_499456_2	1300345.LF41_1445	1.256e-40	158.0	2964P@1|root,2ZTEX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_499456_3	1237149.C900_00535	1.471e-34	139.0	2CIH2@1|root,2ZTG0@2|Bacteria,4NNM2@976|Bacteroidetes,47VGE@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158358_k127_500931_0	760192.Halhy_0886	0.0	1143.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IWHI@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158358_k127_500931_1	391603.FBALC1_10812	1.741e-36	161.0	2D579@1|root,32TID@2|Bacteria,4NX62@976|Bacteroidetes,1I5ZU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_510050_2	1206730.BAGA01000073_gene1928	3.317e-56	198.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4FWSP@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158358_k127_510050_3	452637.Oter_1109	2.667e-40	156.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_510050_0	243231.GSU0075	2.035e-78	282.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,43TW9@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158358_k127_510050_1	543632.JOJL01000035_gene5070	5.543e-68	239.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158358_k127_511228_0	880073.Calab_2821	6.769e-73	276.0	COG0708@1|root,COG2730@1|root,COG0708@2|Bacteria,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.1,3.2.1.4	ko:K01176,ko:K01179	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R06200,R11262,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH13,GH5,GH9	-	CBM_17_28,CBM_2,CBM_3,CBM_6,Cellulase,F5_F8_type_C,Glyco_hydro_26,Glyco_hydro_8
SRR25158358_k127_513631_4	867845.KI911784_gene3392	9.428e-20	91.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,375RW@32061|Chloroflexia	32061|Chloroflexia	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158358_k127_513631_1	1444770.AF72_06940	1.633e-65	239.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1X4HM@135614|Xanthomonadales	135614|Xanthomonadales	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158358_k127_513631_0	767434.Fraau_1741	4.691e-107	353.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1X39D@135614|Xanthomonadales	135614|Xanthomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158358_k127_513631_2	1211114.ALIP01000152_gene2674	3.163e-64	229.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1X3ZJ@135614|Xanthomonadales	135614|Xanthomonadales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158358_k127_513631_3	382245.ASA_2105	5.081e-30	121.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1Y48B@135624|Aeromonadales	135624|Aeromonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158358_k127_517299_1	1150864.MILUP08_45186	1.159e-82	307.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158358_k127_517299_0	1194972.MVAC_29413	6.053e-248	787.0	COG1520@1|root,COG1520@2|Bacteria,2I7MX@201174|Actinobacteria,23FI8@1762|Mycobacteriaceae	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_517299_2	1232437.KL662016_gene1005	7.477e-66	239.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158358_k127_517299_4	502558.EGYY_18230	4.658e-41	162.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia	84998|Coriobacteriia	C	NADH flavin oxidoreductase	-	-	1.3.1.31,1.3.1.34	ko:K00219,ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158358_k127_517299_3	926560.KE387026_gene4179	1.451e-47	175.0	COG0715@1|root,COG0715@2|Bacteria,1WN0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158358_k127_518954_1	749414.SBI_05212	2.871e-96	324.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158358_k127_518954_2	1283299.AUKG01000001_gene3034	6.311e-07	62.0	2EN95@1|root,31MIY@2|Bacteria,2HQ7Y@201174|Actinobacteria,4CRR5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_518954_0	1380390.JIAT01000011_gene2343	1.618e-239	754.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158358_k127_520549_4	391937.NA2_10248	2.653e-05	57.0	COG2050@1|root,COG2050@2|Bacteria,1RDVV@1224|Proteobacteria,2UANF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158358_k127_520549_3	743525.TSC_c04750	1.006e-27	132.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1WKRH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	COGs COG3593 ATP-dependent endonuclease of the OLD family	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
SRR25158358_k127_520549_1	1476876.JOJO01000051_gene91	8.133e-110	362.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158358_k127_520549_2	1206735.BAGG01000249_gene6025	5.422e-69	240.0	COG3832@1|root,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria,4G0ZK@85025|Nocardiaceae	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_520549_0	1163617.SCD_n00393	3.775e-224	706.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158358_k127_522534_3	1896.JOAU01000004_gene45	2.132e-07	59.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158358_k127_522534_2	1380394.JADL01000001_gene1971	1.324e-55	204.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,2JSXD@204441|Rhodospirillales	204441|Rhodospirillales	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158358_k127_522534_1	1380393.JHVP01000002_gene1761	1.072e-93	314.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4EUCR@85013|Frankiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158358_k127_522534_0	1120950.KB892785_gene250	2.206e-217	679.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DNGV@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158358_k127_524705_0	861299.J421_3363	8.651e-135	441.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158358_k127_524705_5	1254432.SCE1572_07855	3.191e-51	205.0	COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
SRR25158358_k127_524705_1	760568.Desku_1855	9.136e-103	345.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,2600U@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158358_k127_524705_4	913325.N799_06730	5.519e-58	220.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1X41Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158358_k127_524705_2	1382306.JNIM01000001_gene2646	7.331e-90	304.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158358_k127_524705_3	1282876.BAOK01000001_gene3452	2.309e-79	267.0	COG0028@1|root,COG2146@1|root,COG0028@2|Bacteria,COG2146@2|Bacteria,1MWKP@1224|Proteobacteria,2TQK6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	poxB	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158358_k127_527964_6	105425.BBPL01000053_gene5641	1.785e-46	174.0	COG4221@1|root,COG4221@2|Bacteria,2I2Z8@201174|Actinobacteria,2NF2P@228398|Streptacidiphilus	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_527964_3	1303518.CCALI_02738	1.929e-64	239.0	COG0066@1|root,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158358_k127_527964_0	292459.STH2116	5.04e-214	676.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158358_k127_527964_4	926550.CLDAP_02880	2.778e-57	205.0	COG2128@1|root,COG2128@2|Bacteria,2G7D8@200795|Chloroflexi	200795|Chloroflexi	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158358_k127_527964_7	1179773.BN6_82130	3.293e-25	120.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria,4E2C3@85010|Pseudonocardiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	GO:0005575,GO:0005576	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
SRR25158358_k127_527964_5	553973.CLOHYLEM_05895	3.476e-51	199.0	COG2159@1|root,COG2159@2|Bacteria,1TSSX@1239|Firmicutes,24C9I@186801|Clostridia,22022@1506553|Lachnoclostridium	186801|Clostridia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158358_k127_527964_2	1123023.JIAI01000001_gene7531	5.061e-76	266.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158358_k127_527964_9	1173027.Mic7113_4360	0.0009281	50.0	COG0517@1|root,COG0784@1|root,COG2198@1|root,COG4251@1|root,COG0517@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4251@2|Bacteria,1GPYK@1117|Cyanobacteria,1HI8A@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_4,PAS_9,PHY,Response_reg
SRR25158358_k127_527964_1	1209984.BN978_03181	2.596e-95	339.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,23817@1762|Mycobacteriaceae	201174|Actinobacteria	C	Acetamidase/Formamidase family	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR25158358_k127_527964_8	1108045.GORHZ_169_00040	0.0002535	53.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4GCKD@85026|Gordoniaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158358_k127_529842_1	526225.Gobs_1729	2.839e-41	158.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2INQP@201174|Actinobacteria,4EVDQ@85013|Frankiales	201174|Actinobacteria	K	Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158358_k127_529842_0	469383.Cwoe_2928	0.0	1120.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPRA@84995|Rubrobacteria	84995|Rubrobacteria	O	Lon protease (S16) C-terminal proteolytic domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158358_k127_537000_8	1304875.JAFZ01000001_gene848	4.765e-14	74.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
SRR25158358_k127_537000_7	1444309.JAQG01000080_gene4027	3.903e-32	139.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,26QQG@186822|Paenibacillaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158358_k127_537000_1	1283299.AUKG01000002_gene4496	2.743e-127	422.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4CRDW@84995|Rubrobacteria	84995|Rubrobacteria	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158358_k127_537000_5	246196.MSMEI_2053	1.061e-59	225.0	COG0624@1|root,COG0624@2|Bacteria,2I9Y6@201174|Actinobacteria,23ER8@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158358_k127_537000_6	43354.JOIJ01000002_gene4177	1.321e-45	181.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158358_k127_537000_2	246196.MSMEI_2056	1.666e-87	301.0	COG2141@1|root,COG2141@2|Bacteria,2GJ04@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158358_k127_537000_3	948106.AWZT01000041_gene3795	8.72e-68	250.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VQQ5@28216|Betaproteobacteria,1K19Z@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	2-deoxy-D-gluconate 3-dehydrogenase	kduD	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158358_k127_537000_9	570967.JMLV01000001_gene2713	4.96e-12	77.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,2JSQF@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158358_k127_537000_0	330084.JNYZ01000015_gene6047	9.167e-309	967.0	COG1529@1|root,COG1529@2|Bacteria,2I8D1@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde oxidase xanthine dehydrogenase, a b hammerhead	-	-	1.3.99.8	ko:K16877	ko00365,ko01120,map00365,map01120	-	R02987	RC01856	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158358_k127_537000_4	644966.Tmar_1491	2.332e-62	218.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,3WDUM@538999|Clostridiales incertae sedis	186801|Clostridia	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158358_k127_537000_10	469383.Cwoe_3872	6.114e-12	69.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CSQX@84995|Rubrobacteria	201174|Actinobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_545103_0	1157490.EL26_03435	7.537e-139	458.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,277ZC@186823|Alicyclobacillaceae	91061|Bacilli	P	Ammonium Transporter Family	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158358_k127_545103_3	661478.OP10G_2104	1.259e-13	78.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158358_k127_545103_2	266117.Rxyl_0405	1.596e-81	280.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_545103_1	266117.Rxyl_0406	3.031e-91	308.0	COG0842@1|root,COG0842@2|Bacteria,2GSKI@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_549281_1	479435.Kfla_2116	4.798e-125	406.0	COG2414@1|root,COG2414@2|Bacteria,2IF1J@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
SRR25158358_k127_549281_0	1366050.N234_30165	9.838e-234	745.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1K6SR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158358_k127_560499_3	469383.Cwoe_1804	9.572e-97	347.0	COG3857@1|root,COG3857@2|Bacteria,2HNUC@201174|Actinobacteria,4CQ2I@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158358_k127_560499_0	562970.Btus_2543	6.233e-155	499.0	COG0473@1|root,COG0473@2|Bacteria,1UJAS@1239|Firmicutes,4HCZN@91061|Bacilli,2787J@186823|Alicyclobacillaceae	91061|Bacilli	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
SRR25158358_k127_560499_5	292459.STH2690	3.1e-39	167.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS
SRR25158358_k127_560499_2	479434.Sthe_1945	9.105e-116	384.0	COG3288@1|root,COG3288@2|Bacteria,2GB86@200795|Chloroflexi,27XYV@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158358_k127_560499_6	40571.JOEA01000001_gene5123	3.042e-28	120.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4E5KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158358_k127_560499_1	882083.SacmaDRAFT_1411	4.288e-145	479.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158358_k127_560499_10	263358.VAB18032_26621	3.193e-07	53.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4D8MG@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_560499_7	1123065.ATWL01000002_gene1615	7.727e-20	91.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_560499_8	591158.SSMG_06229	3.621e-16	87.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_560499_4	1283299.AUKG01000001_gene2216	7.132e-88	299.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
SRR25158358_k127_560499_9	66377.JOBH01000023_gene3459	3.482e-09	59.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158358_k127_564273_4	1122939.ATUD01000005_gene2678	5.921e-19	90.0	COG4221@1|root,COG4221@2|Bacteria,2I5BD@201174|Actinobacteria,4CPN3@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_564273_1	479434.Sthe_0838	4.206e-89	306.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158358_k127_564273_3	1032480.MLP_14430	1.006e-34	145.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4DQ6X@85009|Propionibacteriales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158358_k127_564273_2	469383.Cwoe_5826	2.098e-84	289.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158358_k127_564273_0	469383.Cwoe_5882	2.915e-129	435.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4CPIG@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158358_k127_565612_1	745014.OMB55_00008950	2.144e-25	118.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1J4KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082	Iso_dh
SRR25158358_k127_565612_0	1120948.KB903245_gene3538	8.943e-201	640.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DYSM@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvB	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3003c	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158358_k127_565612_2	1122182.KB903827_gene1190	3.975e-25	118.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4D8VD@85008|Micromonosporales	201174|Actinobacteria	E	Acetolactate synthase small	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158358_k127_565631_0	1380390.JIAT01000010_gene4905	1.688e-151	494.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158358_k127_565631_1	298655.KI912266_gene1102	3.178e-125	437.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158358_k127_565631_2	1123288.SOV_4c03410	2.57e-14	79.0	COG0648@1|root,COG0648@2|Bacteria,1UZNN@1239|Firmicutes,4H20X@909932|Negativicutes	909932|Negativicutes	G	SMART AP endonuclease, family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158358_k127_570407_2	929712.KI912613_gene3398	7.221e-36	142.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4CQ06@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158358_k127_570407_5	1283299.AUKG01000001_gene2463	1.167e-19	92.0	COG1917@1|root,COG1917@2|Bacteria,2HN4T@201174|Actinobacteria,4CQJ2@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_570407_1	1121468.AUBR01000045_gene1801	6.321e-63	227.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,42EU0@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158358_k127_570407_3	479434.Sthe_2063	7.608e-35	138.0	COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158358_k127_570407_4	469383.Cwoe_3402	3.703e-33	140.0	2B412@1|root,31WRB@2|Bacteria,2HY97@201174|Actinobacteria,4CQGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_570407_0	469383.Cwoe_4554	5.962e-97	325.0	COG3294@1|root,COG3294@2|Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158358_k127_570713_1	644966.Tmar_0214	2.617e-113	384.0	COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158358_k127_570713_2	298654.FraEuI1c_0302	1.991e-55	203.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4ESRA@85013|Frankiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158358_k127_570713_0	1278073.MYSTI_07001	1.088e-114	378.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2YV1U@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158358_k127_573704_0	469383.Cwoe_3187	4.633e-297	931.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158358_k127_573704_2	469383.Cwoe_1564	7.585e-92	319.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CQ1Q@84995|Rubrobacteria	84995|Rubrobacteria	T	Response regulator receiver	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158358_k127_573704_1	1283299.AUKG01000005_gene146	2.407e-101	346.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4CREI@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158358_k127_573826_2	509190.Cseg_0271	1.183e-29	125.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158358_k127_573826_1	926550.CLDAP_09200	3.075e-33	132.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158358_k127_573826_0	446462.Amir_5480	4.801e-122	404.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4DXP1@85010|Pseudonocardiales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158358_k127_573826_3	749414.SBI_04380	5.321e-17	91.0	COG1028@1|root,COG1028@2|Bacteria,2GP7P@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_583792_0	469383.Cwoe_2884	5.486e-151	499.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRR25158358_k127_585330_5	882083.SacmaDRAFT_4546	3.366e-22	107.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4E1JU@85010|Pseudonocardiales	201174|Actinobacteria	E	decarboxylase	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158358_k127_585330_1	469383.Cwoe_5838	6.317e-153	506.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158358_k127_585330_2	290397.Adeh_2624	1.381e-79	273.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158358_k127_585330_4	1101188.KI912156_gene4242	5.569e-30	121.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,1W9S8@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158358_k127_585330_3	105420.BBPO01000003_gene1292	1.314e-58	218.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,2NHMI@228398|Streptacidiphilus	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158358_k127_585330_6	591158.SSMG_01600	8.08e-13	74.0	COG0425@1|root,COG0425@2|Bacteria,2GSNH@201174|Actinobacteria	201174|Actinobacteria	O	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158358_k127_585330_0	469383.Cwoe_5571	5.526e-156	506.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4CPIU@84995|Rubrobacteria	84995|Rubrobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158358_k127_585691_1	1223544.GSI01S_29_00670	2.233e-05	56.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4GCHT@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_585691_0	525904.Tter_0038	3.865e-42	159.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158358_k127_588419_4	933115.GPDM_09400	4.049e-17	83.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,26DJX@186818|Planococcaceae	91061|Bacilli	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158358_k127_588419_1	1122216.AUHW01000012_gene1550	5.768e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_588419_0	696747.NIES39_Q02320	2.844e-128	430.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1H7C2@1150|Oscillatoriales	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158358_k127_588419_2	287986.DV20_28585	5.22e-52	191.0	COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria,4E7YD@85010|Pseudonocardiales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158358_k127_588419_3	1122921.KB898204_gene3539	5.402e-37	152.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K18566	ko00332,ko01130,map00332,map01130	-	R10745,R10746	RC00004,RC00096	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
SRR25158358_k127_588419_5	744980.TRICHSKD4_0407	0.0006633	47.0	COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,2TSDV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG0524 Sugar kinases, ribokinase family	kdgK_2	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158358_k127_592489_5	1095769.CAHF01000022_gene214	2.226e-24	109.0	COG2020@1|root,COG2020@2|Bacteria,1PK67@1224|Proteobacteria,2WATQ@28216|Betaproteobacteria,4787Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_592489_6	926560.KE387023_gene3256	2.119e-18	91.0	COG2606@1|root,COG2606@2|Bacteria,1WJSU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YbaK prolyl-tRNA synthetase associated	ebsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158358_k127_592489_1	929712.KI912613_gene3938	6.195e-107	354.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158358_k127_592489_0	370438.PTH_1115	3.118e-114	382.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,2.6.1.102	ko:K12452,ko:K13010	ko00520,map00520	-	R03391,R03392,R10460	RC00006,RC00230,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158358_k127_592489_3	555088.DealDRAFT_0100	3.549e-50	196.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158358_k127_592489_2	266117.Rxyl_0285	4.923e-65	242.0	COG1073@1|root,COG1073@2|Bacteria,2H7CB@201174|Actinobacteria	201174|Actinobacteria	S	COG COG0412 Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis transport and catabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_592489_4	419610.Mext_4401	2.964e-25	105.0	COG2343@1|root,COG2343@2|Bacteria,1RJ3M@1224|Proteobacteria,2U98N@28211|Alphaproteobacteria,1JUC1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158358_k127_593441_3	1463881.KL591035_gene4926	2.896e-81	276.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158358_k127_593441_0	1380390.JIAT01000009_gene637	8.601e-156	508.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4CTX9@84995|Rubrobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158358_k127_593441_8	869210.Marky_1567	2.855e-61	222.0	COG0491@1|root,COG0491@2|Bacteria,1WJ5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158358_k127_593441_1	469371.Tbis_3117	1.686e-141	460.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158358_k127_593441_4	1128421.JAGA01000002_gene533	2.837e-74	263.0	COG3214@1|root,COG3214@2|Bacteria,2NQD2@2323|unclassified Bacteria	2|Bacteria	S	Winged helix DNA-binding domain	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158358_k127_593441_9	345341.KUTG_07807	2.347e-25	112.0	COG1434@1|root,COG1434@2|Bacteria,2IMCB@201174|Actinobacteria	201174|Actinobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158358_k127_593441_2	6500.XP_005092325.1	4.415e-90	322.0	COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria	33208|Metazoa	ET	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
SRR25158358_k127_593441_7	103733.JNYO01000042_gene6070	3.638e-68	246.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4DZJY@85010|Pseudonocardiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158358_k127_593441_5	330084.JNYZ01000033_gene5642	3.56e-71	252.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DZDK@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	yajO	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158358_k127_593441_6	1122138.AQUZ01000015_gene6845	3.41e-69	250.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4DVK7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158358_k127_593441_10	570952.ATVH01000003_gene705	6.181e-07	61.0	COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,2UMJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158358_k127_593441_11	1380390.JIAT01000009_gene1504	5.585e-06	55.0	COG4223@1|root,COG4223@2|Bacteria,2HQ3A@201174|Actinobacteria,4CRJT@84995|Rubrobacteria	84995|Rubrobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_59637_3	580332.Slit_1599	2.591e-05	50.0	COG0739@1|root,COG2931@1|root,COG0739@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,44W46@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_66,HCBP_related,He_PIG,HemolysinCabind
SRR25158358_k127_59637_0	324602.Caur_2263	6.781e-301	957.0	COG0146@1|root,COG0146@2|Bacteria	2|Bacteria	EQ	ligase activity	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158358_k127_59637_1	326427.Cagg_3091	1.633e-269	856.0	COG0145@1|root,COG0145@2|Bacteria,2GAHE@200795|Chloroflexi,37658@32061|Chloroflexia	32061|Chloroflexia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_59637_2	479434.Sthe_0007	1.921e-91	305.0	COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi,27YV0@189775|Thermomicrobia	189775|Thermomicrobia	E	HMGL-like	-	-	4.1.3.46	ko:K18314	-	-	R10674	RC00502,RC01205	ko00000,ko01000	-	-	-	HMGL-like
SRR25158358_k127_604522_3	1266998.ATUJ01000002_gene2072	1.427e-44	171.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,2PW97@265|Paracoccus	28211|Alphaproteobacteria	E	Peptidase family M28	amaB	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158358_k127_604522_2	1125718.HMPREF1318_0205	5.146e-67	229.0	COG2164@1|root,COG2164@2|Bacteria,2HKTF@201174|Actinobacteria,4D5RW@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
SRR25158358_k127_604522_1	760117.JN27_11880	6.247e-122	403.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,473XM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158358_k127_604522_6	72019.SARC_05260T0	1.95e-13	78.0	2CI4P@1|root,2S52N@2759|Eukaryota	2759|Eukaryota	S	OHCU decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox
SRR25158358_k127_604522_5	1206735.BAGG01000115_gene4958	1.282e-18	91.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4G3GV@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158358_k127_604522_0	869210.Marky_0477	4.754e-151	502.0	COG1001@1|root,COG1001@2|Bacteria,1WJ41@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
SRR25158358_k127_604522_4	266117.Rxyl_2836	4.065e-40	158.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CQ7I@84995|Rubrobacteria	84995|Rubrobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_60471_3	35841.BT1A1_2372	6.682e-10	67.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158358_k127_60471_4	512565.AMIS_51450	5.759e-05	54.0	COG4966@1|root,COG4966@2|Bacteria,2GPVW@201174|Actinobacteria,4DK2X@85008|Micromonosporales	201174|Actinobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158358_k127_60471_2	1121428.DESHY_60062___1	1.388e-15	90.0	COG2165@1|root,COG2165@2|Bacteria,1W5JZ@1239|Firmicutes,256FM@186801|Clostridia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158358_k127_60471_1	929712.KI912613_gene3446	2.27e-39	159.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4CQAS@84995|Rubrobacteria	84995|Rubrobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158358_k127_60471_0	42256.RradSPS_0866	6.665e-79	273.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4CP76@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158358_k127_610975_1	749927.AMED_5332	3.231e-60	213.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria,4E2YQ@85010|Pseudonocardiales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158358_k127_610975_0	1128421.JAGA01000003_gene3009	2.236e-94	319.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,SGL,VCBS
SRR25158358_k127_610975_2	1048339.KB913029_gene4254	1.366e-50	193.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158358_k127_610975_3	196162.Noca_2546	3.6e-33	138.0	COG0584@1|root,COG0584@2|Bacteria,2GVYH@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_610975_5	1380390.JIAT01000009_gene1186	2.456e-18	96.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158358_k127_610975_6	413816.BBJP01000036_gene2282	3.659e-09	70.0	COG0681@1|root,arCOG01739@2157|Archaea,2XX34@28890|Euryarchaeota,23VYJ@183963|Halobacteria	183963|Halobacteria	U	COG0681 Signal peptidase I	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158358_k127_610975_4	1379698.RBG1_1C00001G0584	9.336e-22	106.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
SRR25158358_k127_612941_0	469383.Cwoe_0843	2.198e-234	741.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158358_k127_612941_1	929712.KI912613_gene4505	2.363e-33	138.0	COG1376@1|root,COG1376@2|Bacteria,2HQX3@201174|Actinobacteria,4CSPQ@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158358_k127_612941_2	1172179.AUKV01000062_gene466	5.852e-07	60.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF285,Laminin_G_3
SRR25158358_k127_613124_0	1125863.JAFN01000001_gene1474	1.573e-106	355.0	COG1239@1|root,COG1239@2|Bacteria,1MVD4@1224|Proteobacteria,42NRR@68525|delta/epsilon subdivisions,2WJDX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Magnesium chelatase, subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase
SRR25158358_k127_613124_2	593750.Metfor_0883	1.302e-28	129.0	COG1239@1|root,COG1240@1|root,arCOG00438@2157|Archaea,arCOG06472@2157|Archaea,2XUP4@28890|Euryarchaeota,2N9BN@224756|Methanomicrobia	224756|Methanomicrobia	H	AAA domain (dynein-related subfamily)	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
SRR25158358_k127_613124_1	1125863.JAFN01000001_gene555	1.045e-66	241.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158358_k127_61549_0	243233.MCA2161	1.011e-203	656.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_61549_1	926550.CLDAP_27920	1.598e-163	533.0	COG1858@1|root,COG2133@1|root,COG1858@2|Bacteria,COG2133@2|Bacteria,2G989@200795|Chloroflexi	200795|Chloroflexi	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
SRR25158358_k127_61549_2	1122939.ATUD01000001_gene317	8.411e-109	367.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CS8K@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158358_k127_61549_3	1122939.ATUD01000001_gene318	1.849e-103	343.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CR9Y@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR25158358_k127_61549_4	1246474.ANBE01000038_gene4187	7.293e-10	61.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4EHFU@85012|Streptosporangiales	201174|Actinobacteria	G	Periplasmic binding protein domain	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158358_k127_619734_6	247639.MGP2080_08169	1.866e-12	68.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1J4H7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_619734_0	1273538.G159_05140	2.083e-104	351.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,26EMD@186818|Planococcaceae	91061|Bacilli	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158358_k127_619734_1	5062.CADAORAP00002302	7.796e-47	172.0	2CUWZ@1|root,2RPHZ@2759|Eukaryota,38T8H@33154|Opisthokonta,3PUXW@4751|Fungi,3RE5V@4890|Ascomycota,20QP4@147545|Eurotiomycetes,3SDCI@5042|Eurotiales	4751|Fungi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158358_k127_619734_5	1037409.BJ6T_61770	1.153e-13	83.0	2FGTF@1|root,348NS@2|Bacteria,1P2M9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_619734_4	1313172.YM304_29820	1.53e-21	103.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	yhcR	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	ChitinaseA_N,Glyco_hydro_18,Glyco_hydro_53,Reprolysin_4,fn3
SRR25158358_k127_619734_2	1150864.MILUP08_41399	1.071e-45	179.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DBTI@85008|Micromonosporales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA_2
SRR25158358_k127_619734_7	266835.14021447	1.48e-09	63.0	2EM0A@1|root,33EPT@2|Bacteria,1N2DC@1224|Proteobacteria,2UBU5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_619734_3	1380390.JIAT01000010_gene4281	3.06e-33	130.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_624909_2	1403313.AXBR01000017_gene3647	1.386e-14	74.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus	91061|Bacilli	E	Belongs to the arginase family	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158358_k127_624909_0	1173023.KE650771_gene2664	3.363e-118	396.0	COG0154@1|root,COG0154@2|Bacteria,1G1MZ@1117|Cyanobacteria,1JJV1@1189|Stigonemataceae	1117|Cyanobacteria	J	Amidase	nylA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	iJN678.nylA	Amidase
SRR25158358_k127_624909_1	471852.Tcur_0792	7.757e-71	248.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4EFY5@85012|Streptosporangiales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158358_k127_624909_3	661478.OP10G_0937	0.0003437	49.0	COG1587@1|root,COG1587@2|Bacteria	2|Bacteria	H	uroporphyrinogen-III synthase activity	cobA	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,TP_methylase
SRR25158358_k127_62617_2	1123023.JIAI01000007_gene1953	2.798e-46	174.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158358_k127_62617_1	301.JNHE01000002_gene2356	2.006e-59	222.0	COG0404@1|root,COG3665@1|root,COG0404@2|Bacteria,COG3665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1YI61@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Domain of unknown function (DUF1989)	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1989,GCV_T,GCV_T_C
SRR25158358_k127_62617_0	1026882.MAMP_01137	6.857e-209	666.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S oxidoreductase	dgcB	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
SRR25158358_k127_629268_7	999541.bgla_1g21040	1.954e-12	72.0	COG0446@1|root,COG1752@1|root,COG0446@2|Bacteria,COG1752@2|Bacteria,1NR3M@1224|Proteobacteria,2VKIS@28216|Betaproteobacteria,1K10K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3734,Patatin,Pyr_redox_2,Reductase_C
SRR25158358_k127_629268_6	1232410.KI421413_gene951	2.202e-31	124.0	2DNW5@1|root,32ZGI@2|Bacteria,1MZA8@1224|Proteobacteria,4310I@68525|delta/epsilon subdivisions,2WWS8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
SRR25158358_k127_629268_4	1236902.ANAS01000013_gene1279	2.409e-36	144.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4EJ0H@85012|Streptosporangiales	201174|Actinobacteria	O	Redoxin	ahpE	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158358_k127_629268_5	1394178.AWOO02000089_gene1096	8.086e-36	147.0	COG0596@1|root,COG0596@2|Bacteria,2I8EU@201174|Actinobacteria,4EQPH@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	lipV	GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575	-	ko:K19311	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158358_k127_629268_0	1463855.JOHV01000020_gene3031	3.865e-191	608.0	COG0160@1|root,COG0160@2|Bacteria,2I2F3@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158358_k127_629268_1	649638.Trad_1204	5.637e-159	515.0	COG0624@1|root,COG0624@2|Bacteria,1WKXT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
SRR25158358_k127_629268_3	1146883.BLASA_1459	5.396e-57	214.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRR25158358_k127_629268_2	710421.Mycch_3520	3.43e-59	212.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria,234QX@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158358_k127_632331_2	1177594.MIC448_1580004	4.555e-94	327.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4FK3Z@85023|Microbacteriaceae	201174|Actinobacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158358_k127_632331_10	1216967.L100_08119	0.0004084	48.0	COG1826@1|root,COG1826@2|Bacteria,4PFQP@976|Bacteroidetes,1IGIN@117743|Flavobacteriia,34RIY@308865|Elizabethkingia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158358_k127_632331_6	42256.RradSPS_1961	3.2e-52	198.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158358_k127_632331_1	1267535.KB906767_gene1478	1.553e-106	360.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158358_k127_632331_0	1267535.KB906767_gene1479	8.188e-129	429.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
SRR25158358_k127_632331_4	29495.EA26_04880	4.737e-85	291.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1XU34@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
SRR25158358_k127_632331_3	2340.JV46_27550	5.259e-92	312.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
SRR25158358_k127_632331_8	1049564.TevJSym_ai00550	6.794e-33	142.0	COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	VV0993	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_632331_7	402881.Plav_3476	1.956e-37	149.0	COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,2UUUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158358_k127_632331_9	1040983.AXAE01000012_gene2013	1.425e-25	109.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_632331_5	1283299.AUKG01000004_gene1147	1.12e-68	241.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CQT2@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158358_k127_635866_2	1382356.JQMP01000003_gene2216	2.794e-64	231.0	arCOG06227@1|root,2ZB70@2|Bacteria,2GAEH@200795|Chloroflexi,27Z5J@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158358_k127_635866_4	263358.VAB18032_11050	4.429e-34	143.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4DCMF@85008|Micromonosporales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158358_k127_635866_0	479435.Kfla_5495	3.074e-130	437.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4DQD1@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158358_k127_635866_3	1079986.JH164841_gene5057	1.133e-41	172.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_635866_1	1283299.AUKG01000002_gene4006	7.109e-101	336.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4CRVP@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_636453_1	1385511.N783_12115	1.007e-94	324.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,2Y95S@289201|Pontibacillus	91061|Bacilli	I	Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158358_k127_636453_2	404589.Anae109_0136	6.723e-25	121.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MVME@1224|Proteobacteria,43AKG@68525|delta/epsilon subdivisions,2X60I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF
SRR25158358_k127_636453_0	1211814.CAPG01000064_gene3030	6.417e-104	361.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_636453_3	1380394.JADL01000003_gene5217	2.614e-05	54.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2JRV2@204441|Rhodospirillales	204441|Rhodospirillales	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158358_k127_646037_1	1380390.JIAT01000011_gene2610	1.31e-83	287.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CPA2@84995|Rubrobacteria	84995|Rubrobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158358_k127_646037_6	1122239.AULS01000009_gene1519	2.101e-52	191.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4FNDD@85023|Microbacteriaceae	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158358_k127_646037_0	293826.Amet_4458	1.178e-128	423.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,36F8Y@31979|Clostridiaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158358_k127_646037_8	1283299.AUKG01000001_gene2650	7.914e-44	168.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158358_k127_646037_13	983544.Lacal_0393	2.586e-11	66.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1I55H@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158358_k127_646037_4	1122939.ATUD01000003_gene3583	3.29e-64	226.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158358_k127_646037_9	888746.HMPREF9180_0077	2.447e-32	136.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158358_k127_646037_2	1380390.JIAT01000011_gene2603	2.029e-70	242.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158358_k127_646037_7	1348662.CARG_01420	1.277e-45	168.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,22MWH@1653|Corynebacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158358_k127_646037_10	1318617.MGM1_0840	1.108e-24	104.0	COG0199@1|root,COG0199@2|Bacteria,3WTWI@544448|Tenericutes	544448|Tenericutes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158358_k127_646037_3	469383.Cwoe_1352	2.871e-70	247.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158358_k127_646037_11	1231241.Mc24_04220	1.317e-23	104.0	COG0198@1|root,COG0198@2|Bacteria,2GD31@200918|Thermotogae	200918|Thermotogae	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158358_k127_646037_5	469383.Cwoe_1350	3.456e-59	214.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158358_k127_646037_12	857293.CAAU_1218	1.592e-22	102.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,36KIV@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158358_k127_64833_4	883103.HMPREF9703_01612	3.76e-11	64.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,27FKD@186828|Carnobacteriaceae	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158358_k127_64833_0	1304284.L21TH_1118	1.493e-175	569.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,36E6C@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158358_k127_64833_1	65093.PCC7418_3088	1.88e-100	345.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158358_k127_64833_2	324602.Caur_0549	2.163e-90	314.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158358_k127_64833_3	662479.C440_00610	1.083e-59	220.0	arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158358_k127_654701_2	1283299.AUKG01000004_gene969	1.858e-14	85.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158358_k127_654701_1	469383.Cwoe_3035	6.492e-22	108.0	COG0816@1|root,COG0816@2|Bacteria,2HPE8@201174|Actinobacteria,4CQSC@84995|Rubrobacteria	84995|Rubrobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158358_k127_654701_0	1235279.C772_02128	6.367e-105	359.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,26DYV@186818|Planococcaceae	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158358_k127_657489_3	443143.GM18_1413	2.06e-05	56.0	2DST5@1|root,33HC3@2|Bacteria,1NMTA@1224|Proteobacteria,42XYN@68525|delta/epsilon subdivisions,2WT9U@28221|Deltaproteobacteria,43VXG@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_657489_0	404589.Anae109_2250	7.871e-147	488.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158358_k127_657489_1	1121405.dsmv_2999	3.492e-76	281.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R7US@1224|Proteobacteria,42PFT@68525|delta/epsilon subdivisions,2WMBJ@28221|Deltaproteobacteria,2MJ1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,TPP_enzyme_C
SRR25158358_k127_657489_2	696281.Desru_2277	5.57e-44	169.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,260SY@186807|Peptococcaceae	186801|Clostridia	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158358_k127_659560_2	1287116.X734_19005	4.402e-64	224.0	COG0395@1|root,COG0395@2|Bacteria,1MXTE@1224|Proteobacteria,2TSM4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K17323	ko02010,map02010	M00207,M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.35	-	-	BPD_transp_1
SRR25158358_k127_659560_3	1449126.JQKL01000016_gene2857	1.494e-58	223.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia	186801|Clostridia	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R02984,R05176	RC00289,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158358_k127_659560_1	765698.Mesci_6401	1.121e-79	276.0	COG0395@1|root,COG0395@2|Bacteria,1MXTE@1224|Proteobacteria,2TSM4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K17323	ko02010,map02010	M00207,M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.35	-	-	BPD_transp_1
SRR25158358_k127_659560_0	224911.27354600	6.828e-103	347.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSXM@28211|Alphaproteobacteria,3JV9U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158358_k127_659560_4	390989.JOEG01000028_gene5496	1.533e-26	117.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4DH6N@85008|Micromonosporales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158358_k127_671817_0	1382358.JHVN01000007_gene307	6.006e-114	380.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,21V54@150247|Anoxybacillus	1239|Firmicutes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
SRR25158358_k127_671817_2	1192034.CAP_3089	5.171e-18	85.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
SRR25158358_k127_673059_3	469383.Cwoe_0014	9.714e-39	153.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158358_k127_673059_0	469383.Cwoe_0015	1.251e-106	361.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158358_k127_673059_1	253839.SSNG_03508	4.7e-75	274.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria	201174|Actinobacteria	M	penicillin-binding protein	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158358_k127_673059_2	1380390.JIAT01000009_gene1776	1.045e-56	202.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158358_k127_674263_6	1122939.ATUD01000019_gene1557	1.488e-51	186.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CP63@84995|Rubrobacteria	84995|Rubrobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158358_k127_674263_11	1380390.JIAT01000010_gene4549	2.03e-41	172.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158358_k127_674263_0	1120985.AUMI01000015_gene1658	8.709e-102	349.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4H2Q8@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158358_k127_674263_10	1380390.JIAT01000010_gene4537	2.024e-42	165.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CQ05@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158358_k127_674263_4	266117.Rxyl_1402	9.441e-69	257.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158358_k127_674263_5	469383.Cwoe_3514	4.882e-66	229.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158358_k127_674263_1	1283299.AUKG01000002_gene4926	2.334e-96	324.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158358_k127_674263_9	1453496.AT03_17465	4.432e-46	187.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158358_k127_674263_2	935948.KE386494_gene261	6.564e-90	314.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,42ENB@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158358_k127_674263_3	469383.Cwoe_3518	4.103e-83	289.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158358_k127_674263_12	469383.Cwoe_3519	1.357e-25	117.0	COG0597@1|root,COG0597@2|Bacteria,2HP4E@201174|Actinobacteria,4CQFY@84995|Rubrobacteria	84995|Rubrobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158358_k127_674263_13	1123290.AUDQ01000026_gene3145	1.253e-18	90.0	COG1734@1|root,COG1734@2|Bacteria,1V4KF@1239|Firmicutes,4HHBC@91061|Bacilli,26I4S@186818|Planococcaceae	91061|Bacilli	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158358_k127_674263_15	1269813.ATUL01000020_gene349	1.888e-14	76.0	COG1872@1|root,COG1872@2|Bacteria,1QKJ0@1224|Proteobacteria,1SDPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158358_k127_674263_17	1304872.JAGC01000009_gene1223	4.74e-08	62.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WPC4@28221|Deltaproteobacteria,2MBBV@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158358_k127_674263_14	1122939.ATUD01000019_gene1542	9.825e-15	78.0	COG0762@1|root,COG0762@2|Bacteria,2HR5Q@201174|Actinobacteria,4CT15@84995|Rubrobacteria	84995|Rubrobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158358_k127_674263_7	1380390.JIAT01000010_gene4526	5.264e-49	183.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158358_k127_674263_8	469383.Cwoe_3523	5.419e-48	181.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158358_k127_674263_16	861299.J421_3513	9.615e-11	68.0	COG0617@1|root,COG0617@2|Bacteria,1ZSKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158358_k127_678265_1	469383.Cwoe_3731	7.868e-105	353.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CPBT@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158358_k127_678265_4	74547.PMT_1998	6.333e-32	134.0	COG0204@1|root,COG0204@2|Bacteria,1G173@1117|Cyanobacteria,1MKSH@1212|Prochloraceae	1117|Cyanobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158358_k127_678265_3	649764.HMPREF0762_00033	4.741e-51	192.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CV84@84998|Coriobacteriia	84998|Coriobacteriia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158358_k127_678265_0	666685.R2APBS1_1615	8.77e-119	398.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1X36A@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158358_k127_678265_2	469383.Cwoe_3737	5.939e-66	236.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158358_k127_680250_0	298654.FraEuI1c_0693	9.118e-64	228.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4ERQB@85013|Frankiales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158358_k127_680250_5	697281.Mahau_0787	2.194e-10	70.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,42HHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158358_k127_680250_3	1033730.CAHG01000008_gene3005	1.004e-16	88.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4DMXW@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158358_k127_680250_2	234267.Acid_0793	3.099e-21	100.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_680250_4	316274.Haur_4470	3.222e-12	76.0	COG3404@1|root,COG3404@2|Bacteria,2G70J@200795|Chloroflexi,375J7@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SRR25158358_k127_680250_1	1288083.AUKR01000002_gene4615	1.386e-60	227.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,TIG
SRR25158358_k127_690874_1	1123023.JIAI01000006_gene93	8.372e-67	232.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4E1WD@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158358_k127_690874_0	1298863.AUEP01000004_gene1990	5.554e-188	599.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4DPS5@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_690874_2	469383.Cwoe_5832	1.86e-51	193.0	COG1877@1|root,COG1877@2|Bacteria,2HP2R@201174|Actinobacteria,4CQDQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158358_k127_690874_4	1122939.ATUD01000026_gene2811	9.067e-21	98.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158358_k127_690874_3	1122939.ATUD01000026_gene2811	1.084e-24	112.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158358_k127_692104_2	1047013.AQSP01000078_gene2052	6.49e-21	94.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
SRR25158358_k127_692104_0	448385.sce7789	1.788e-55	210.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
SRR25158358_k127_692104_1	1227495.C487_03313	1.304e-36	149.0	COG3119@1|root,arCOG02787@2157|Archaea,2XUWX@28890|Euryarchaeota,23S64@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1,3.1.6.6	ko:K01130,ko:K01133	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158358_k127_692963_13	211114.JOEF01000001_gene7598	2.662e-12	68.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4E1AE@85010|Pseudonocardiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	adhB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051704,GO:0071944	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_692963_2	189753.AXAS01000002_gene5361	1.452e-97	324.0	COG1335@1|root,COG3386@1|root,COG1335@2|Bacteria,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,3JUN4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	GQ	SMP-30/Gluconolaconase/LRE-like region	MA20_13995	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Isochorismatase,SGL
SRR25158358_k127_692963_0	1040989.AWZU01000003_gene6681	1.399e-128	420.0	COG1335@1|root,COG3386@1|root,COG1335@2|Bacteria,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,3JUN4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	GQ	SMP-30/Gluconolaconase/LRE-like region	MA20_13995	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Isochorismatase,SGL
SRR25158358_k127_692963_12	882.DVU_0083	9.552e-17	84.0	COG1547@1|root,COG1547@2|Bacteria,1NPV3@1224|Proteobacteria,42XAN@68525|delta/epsilon subdivisions,2WSKH@28221|Deltaproteobacteria,2MDE5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158358_k127_692963_8	1283299.AUKG01000001_gene2258	7.703e-42	163.0	COG1216@1|root,COG1216@2|Bacteria,2I2J1@201174|Actinobacteria,4CQYW@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158358_k127_692963_16	1121928.AUHE01000002_gene823	1.28e-05	56.0	COG1434@1|root,COG1434@2|Bacteria,2H885@201174|Actinobacteria,4GA64@85026|Gordoniaceae	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158358_k127_692963_7	929712.KI912613_gene2314	5.831e-61	225.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4CQ5H@84995|Rubrobacteria	84995|Rubrobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C
SRR25158358_k127_692963_11	479434.Sthe_1403	5.314e-36	139.0	COG1975@1|root,COG1975@2|Bacteria,2G6Z8@200795|Chloroflexi,27YDJ@189775|Thermomicrobia	189775|Thermomicrobia	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
SRR25158358_k127_692963_5	42256.RradSPS_2622	2.172e-89	319.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CRRF@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158358_k127_692963_3	235985.BBPN01000021_gene6306	2.188e-96	323.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,2NG3V@228398|Streptacidiphilus	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158358_k127_692963_4	1038862.KB893829_gene5025	6.131e-94	317.0	COG0491@1|root,COG0491@2|Bacteria,1Q8EW@1224|Proteobacteria,2TUW0@28211|Alphaproteobacteria,3JWAV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	MA20_13990	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158358_k127_692963_1	330214.NIDE3114	2.698e-108	359.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158358_k127_692963_6	469383.Cwoe_0747	3.001e-77	272.0	COG1071@1|root,COG1071@2|Bacteria,2IC03@201174|Actinobacteria,4CQ7Q@84995|Rubrobacteria	201174|Actinobacteria	C	PFAM dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158358_k127_692963_15	1196323.ALKF01000178_gene233	4.038e-06	52.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158358_k127_692963_17	1048339.KB913029_gene4929	0.0004623	46.0	COG1725@1|root,COG1910@1|root,COG1725@2|Bacteria,COG1910@2|Bacteria,2H32X@201174|Actinobacteria,4ETSA@85013|Frankiales	201174|Actinobacteria	K	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PBP_like
SRR25158358_k127_692963_14	977880.RALTA_B0581	4.172e-11	73.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_692963_9	1192034.CAP_0075	4.348e-41	158.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z13I@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158358_k127_692963_10	1089551.KE386572_gene3487	1.515e-39	157.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,4BR94@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158358_k127_702977_10	525904.Tter_2518	2.163e-06	59.0	COG4948@1|root,COG4948@2|Bacteria,2NR3V@2323|unclassified Bacteria	2|Bacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158358_k127_702977_0	196162.Noca_4966	1.602e-207	670.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158358_k127_702977_4	710687.KI912270_gene4481	1.94e-60	215.0	COG1309@1|root,COG1309@2|Bacteria,2GJVD@201174|Actinobacteria,2357N@1762|Mycobacteriaceae	710687.KI912270_gene4481|-	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_702977_9	1120947.ATUX01000010_gene265	4.39e-11	75.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria,4D3GK@85005|Actinomycetales	201174|Actinobacteria	ET	ABC transporter substrate-binding protein	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
SRR25158358_k127_702977_7	1236902.ANAS01000038_gene3057	1.352e-20	108.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4EGC3@85012|Streptosporangiales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158358_k127_702977_5	67373.JOBF01000048_gene1497	6.241e-25	109.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158358_k127_702977_1	1411685.U062_00561	4.381e-73	251.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1J5R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573	Flavoprotein
SRR25158358_k127_702977_6	1463921.JODF01000060_gene1873	9.89e-23	103.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158358_k127_702977_3	477974.Daud_0538	8.983e-67	259.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DC@186807|Peptococcaceae	186801|Clostridia	T	Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,PAS,PocR,SBP_bac_3
SRR25158358_k127_702977_2	42256.RradSPS_2112	1.34e-71	253.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_702977_8	42256.RradSPS_2113	7.684e-14	73.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_703855_5	1297569.MESS2_760077	5.41e-61	219.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lactamase_B_2,Lactamase_B_3
SRR25158358_k127_703855_3	1040986.ATYO01000017_gene893	5.203e-69	252.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2V7UN@28211|Alphaproteobacteria,43PXP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158358_k127_703855_2	1380394.JADL01000003_gene5149	4.456e-87	314.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,2TR35@28211|Alphaproteobacteria,2JW2W@204441|Rhodospirillales	204441|Rhodospirillales	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_703855_0	933262.AXAM01000013_gene1312	1.612e-93	315.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2MIUS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158358_k127_703855_6	344747.PM8797T_03429	4.66e-24	105.0	COG1917@1|root,COG1917@2|Bacteria,2J134@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_703855_4	1120950.KB892757_gene6418	3.08e-63	231.0	COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4DSSS@85009|Propionibacteriales	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158358_k127_703855_1	1120950.KB892757_gene6417	5.616e-91	325.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DPA7@85009|Propionibacteriales	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_710393_0	351627.Csac_2061	2.361e-155	499.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,42F68@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158358_k127_710393_2	1379270.AUXF01000002_gene1182	1.246e-74	263.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158358_k127_710393_1	1380390.JIAT01000009_gene360	2.942e-89	307.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CQIN@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158358_k127_710393_6	926550.CLDAP_09200	9.184e-25	107.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158358_k127_710393_3	136273.GY22_04940	5.586e-60	215.0	COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria,1WABF@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158358_k127_710393_8	1283299.AUKG01000002_gene3883	0.0007587	49.0	2A1TX@1|root,30Q2V@2|Bacteria,2HR8N@201174|Actinobacteria,4CT50@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_710393_4	469383.Cwoe_4624	8.427e-58	214.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CQG3@84995|Rubrobacteria	84995|Rubrobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158358_k127_710393_7	929712.KI912613_gene2876	1.814e-24	105.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158358_k127_710393_5	469383.Cwoe_4622	3.027e-30	128.0	COG0711@1|root,COG0711@2|Bacteria,2HR5V@201174|Actinobacteria,4CT1D@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158358_k127_712725_6	1286631.X805_15040	8.395e-16	89.0	COG2453@1|root,COG2453@2|Bacteria,1QZXA@1224|Proteobacteria	1224|Proteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
SRR25158358_k127_712725_4	1229172.JQFA01000002_gene2579	6.916e-60	220.0	COG1853@1|root,COG1853@2|Bacteria,1G4QZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158358_k127_712725_1	118163.Ple7327_2338	6.962e-118	391.0	COG0624@1|root,COG0624@2|Bacteria,1G3WM@1117|Cyanobacteria	1117|Cyanobacteria	E	peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158358_k127_712725_2	118163.Ple7327_2339	1.661e-88	315.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1611,DUF1611_N,Peptidase_S8
SRR25158358_k127_712725_3	644283.Micau_0368	8.594e-61	228.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4D9V1@85008|Micromonosporales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158358_k127_712725_5	1161401.ASJA01000001_gene322	1.661e-22	102.0	COG0457@1|root,COG0457@2|Bacteria	1161401.ASJA01000001_gene322|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_712725_0	457570.Nther_0549	1.086e-241	771.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia	186801|Clostridia	L	DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158358_k127_713903_0	469383.Cwoe_3249	7.336e-157	508.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158358_k127_713903_1	1283299.AUKG01000002_gene5157	5.304e-156	508.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CS83@84995|Rubrobacteria	84995|Rubrobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158358_k127_713903_7	1121927.GOHSU_42_00440	0.0002521	51.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4GDZ7@85026|Gordoniaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158358_k127_713903_2	1380390.JIAT01000010_gene4814	1.018e-152	490.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158358_k127_713903_6	1122939.ATUD01000003_gene3642	9.052e-14	83.0	COG1514@1|root,COG1514@2|Bacteria,2HNKJ@201174|Actinobacteria,4CQT5@84995|Rubrobacteria	84995|Rubrobacteria	J	LigT like Phosphoesterase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158358_k127_713903_4	1380347.JNII01000011_gene944	3.894e-90	313.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158358_k127_713903_5	1380390.JIAT01000010_gene4817	1.16e-18	94.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SRR25158358_k127_713903_3	1380390.JIAT01000009_gene595	1.066e-118	389.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4CPYV@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158358_k127_715659_1	795797.C497_06389	1.629e-157	519.0	COG0145@1|root,arCOG01511@2157|Archaea,2XT1J@28890|Euryarchaeota,23SV5@183963|Halobacteria	183963|Halobacteria	E	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_715659_3	1463854.JOHT01000003_gene6049	6.566e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,2IFBN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_715659_4	1380347.JNII01000005_gene3759	1.893e-31	132.0	2DK6R@1|root,32UEG@2|Bacteria,2INPY@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158358_k127_715659_2	390989.JOEG01000019_gene5932	2.55e-75	269.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	nucA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
SRR25158358_k127_715659_0	1122622.ATWJ01000014_gene448	4.443e-185	585.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158358_k127_716929_0	47839.CCAU010000005_gene481	7.339e-120	409.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,2366A@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158358_k127_716929_2	1035308.AQYY01000001_gene3245	5.63e-09	60.0	2DNVA@1|root,32ZBE@2|Bacteria,1W480@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_716929_1	935840.JAEQ01000006_gene2470	1.128e-62	218.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2TT7X@28211|Alphaproteobacteria,43HEM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Ectoine utilization protein EutC	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158358_k127_717865_3	309801.trd_A0429	9.393e-07	58.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi,27Y50@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_717865_1	58123.JOFJ01000007_gene631	4.817e-69	244.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4EIHD@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158358_k127_717865_0	1380390.JIAT01000010_gene4131	6.119e-82	287.0	COG0477@1|root,COG2814@2|Bacteria,2HQMP@201174|Actinobacteria,4CS79@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_717865_2	44060.JODL01000024_gene308	1.505e-58	225.0	COG0500@1|root,COG2226@2|Bacteria,2I36Q@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158358_k127_727318_2	868595.Desca_1450	8.32e-44	164.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158358_k127_727318_0	264732.Moth_1246	1.593e-125	409.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
SRR25158358_k127_727318_1	706587.Desti_3747	2.07e-105	351.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,2MQAB@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158358_k127_728089_4	748247.AZKH_0540	6.708e-75	256.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2VMAI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158358_k127_728089_3	1265310.CCBD010000058_gene1383	1.076e-86	295.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23F6M@1762|Mycobacteriaceae	201174|Actinobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158358_k127_728089_2	1121935.AQXX01000089_gene4656	5.222e-129	421.0	COG0655@1|root,COG0655@2|Bacteria,1N5Q7@1224|Proteobacteria,1RY1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158358_k127_728089_0	1382304.JNIL01000001_gene1689	1.892e-148	482.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli	91061|Bacilli	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158358_k127_728089_7	1380347.JNII01000005_gene3498	0.0004793	45.0	28THW@1|root,2ZFRR@2|Bacteria,2GQMQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_728089_5	717785.HYPMC_4901	1.258e-34	145.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,3N8E7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158358_k127_728089_1	1333998.M2A_3075	3.349e-130	423.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria,4BRMY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Fructose-bisphosphate aldolase class-I	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR25158358_k127_728089_6	1828.JOKB01000008_gene355	6.417e-17	81.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4FVQ5@85025|Nocardiaceae	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158358_k127_730205_4	266117.Rxyl_0401	7.369e-118	390.0	COG1082@1|root,COG1082@2|Bacteria,2HRE6@201174|Actinobacteria,4CTCA@84995|Rubrobacteria	84995|Rubrobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158358_k127_730205_0	1122939.ATUD01000001_gene316	2.659e-176	569.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CPEI@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158358_k127_730205_8	266117.Rxyl_3000	7.138e-69	241.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4CSD7@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_730205_7	1283299.AUKG01000002_gene5345	6.742e-79	280.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4CQYT@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158358_k127_730205_11	1382356.JQMP01000003_gene1356	6.36e-05	55.0	COG1310@1|root,COG1310@2|Bacteria,2G7CC@200795|Chloroflexi,27YR1@189775|Thermomicrobia	189775|Thermomicrobia	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158358_k127_730205_6	1382306.JNIM01000001_gene1035	1.498e-107	362.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158358_k127_730205_1	1144275.COCOR_06186	3.455e-152	491.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158358_k127_730205_3	469383.Cwoe_4683	1.708e-125	411.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_730205_5	1283299.AUKG01000003_gene499	9.612e-115	384.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CQCU@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158358_k127_730205_2	1283299.AUKG01000001_gene2787	4.343e-134	440.0	COG2195@1|root,COG2195@2|Bacteria,2IHIV@201174|Actinobacteria,4CPUC@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158358_k127_730205_10	929712.KI912613_gene2826	1.774e-30	124.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4CQEM@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158358_k127_730205_9	1521187.JPIM01000060_gene2905	4.754e-38	147.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158358_k127_734727_2	1464048.JNZS01000034_gene2628	7.252e-25	121.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158358_k127_734727_0	751945.Theos_0658	3.814e-85	295.0	COG1181@1|root,COG1181@2|Bacteria,1WIJ8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158358_k127_734727_1	1240349.ANGC01000021_gene3480	9.185e-34	145.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158358_k127_745019_0	1296990.H845_96	3.06e-54	209.0	2DBW9@1|root,2ZBFB@2|Bacteria,1R3EM@1224|Proteobacteria,2U3BC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_745019_1	1380390.JIAT01000010_gene3321	9.501e-16	83.0	COG1414@1|root,COG1414@2|Bacteria,2HGKG@201174|Actinobacteria,4CTN3@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158358_k127_745504_1	284031.JNXD01000040_gene7192	6.569e-08	55.0	COG0346@1|root,COG0346@2|Bacteria,2IM1B@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_745504_0	1150599.MPHLEI_04033	3.513e-88	317.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,232BD@1762|Mycobacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158358_k127_75454_0	1449353.JQMQ01000005_gene991	3.22e-115	385.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,2NFU5@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158358_k127_75454_2	1382356.JQMP01000003_gene1747	5.251e-60	228.0	COG0842@1|root,COG0842@2|Bacteria,2G7B2@200795|Chloroflexi,27YZ9@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158358_k127_75454_5	595537.Varpa_4435	1.926e-11	72.0	COG3631@1|root,COG3631@2|Bacteria,1RM0Y@1224|Proteobacteria,2VTQT@28216|Betaproteobacteria,4AJF6@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K07255	ko00430,map00430	-	R01685	RC00062	ko00000,ko00001,ko01000	-	-	-	SnoaL_2
SRR25158358_k127_75454_1	1380390.JIAT01000002_gene6014	2.464e-83	282.0	COG4221@1|root,COG4221@2|Bacteria,2IAVE@201174|Actinobacteria,4CR7Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_75454_3	196162.Noca_4380	7.696e-39	159.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4DRCX@85009|Propionibacteriales	201174|Actinobacteria	O	PFAM Sucraseferredoxin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158358_k127_75454_4	1122939.ATUD01000003_gene3632	9.169e-19	92.0	2AV0E@1|root,31KQ8@2|Bacteria,2HPHG@201174|Actinobacteria,4CQVP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_756776_7	690850.Desaf_2499	1.017e-10	64.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158358_k127_756776_5	469383.Cwoe_1137	2.749e-13	73.0	2A23K@1|root,30QDU@2|Bacteria,2HRA7@201174|Actinobacteria,4CT74@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_756776_1	1223523.H340_10370	2.382e-103	357.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158358_k127_756776_2	1223523.H340_11800	3.41e-88	301.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
SRR25158358_k127_756776_0	186497.PF0547	8.276e-161	523.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158358_k127_756776_3	266117.Rxyl_2923	1.252e-75	267.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4CQPH@84995|Rubrobacteria	84995|Rubrobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158358_k127_756776_8	1125863.JAFN01000001_gene2355	2.81e-07	64.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_756776_6	1306174.JODP01000005_gene1572	2.465e-12	80.0	2E9GJ@1|root,333PP@2|Bacteria,2HC60@201174|Actinobacteria	201174|Actinobacteria	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
SRR25158358_k127_756776_4	66692.ABC1313	1.152e-68	241.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_760550_0	266117.Rxyl_2466	3.862e-240	751.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158358_k127_760550_4	469383.Cwoe_3465	4.994e-26	111.0	COG2452@1|root,COG3585@1|root,COG2452@2|Bacteria,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4CQRP@84995|Rubrobacteria	84995|Rubrobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,TOBE
SRR25158358_k127_760550_3	1380390.JIAT01000010_gene4654	1.43e-43	170.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4CQIG@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158358_k127_760550_2	469383.Cwoe_3463	1.705e-62	234.0	COG0555@1|root,COG0555@2|Bacteria,2I4C5@201174|Actinobacteria,4CQ7S@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158358_k127_760550_1	469383.Cwoe_0507	3.984e-96	337.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4CR1Z@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
SRR25158358_k127_765873_3	644966.Tmar_0590	1.165e-46	177.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3WDHJ@538999|Clostridiales incertae sedis	186801|Clostridia	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
SRR25158358_k127_765873_1	1111069.TCCBUS3UF1_16570	3.298e-78	270.0	COG0107@1|root,COG0107@2|Bacteria,1WJ30@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158358_k127_765873_5	266117.Rxyl_1104	1.649e-38	158.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CQ9Q@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158358_k127_765873_4	644282.Deba_1426	6.49e-42	175.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158358_k127_765873_0	1122963.AUHB01000001_gene676	2.365e-81	286.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,36XCQ@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Histidinol dehydrogenase	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158358_k127_765873_2	525904.Tter_0658	3.173e-68	246.0	COG0040@1|root,COG0040@2|Bacteria,2NPA9@2323|unclassified Bacteria	2|Bacteria	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_1909	HisG,HisG_C
SRR25158358_k127_765873_7	1429851.X548_07650	2.962e-19	91.0	COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales	135614|Xanthomonadales	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
SRR25158358_k127_765873_6	477974.Daud_1623	1.642e-37	147.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,260RZ@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158358_k127_766506_6	573064.Mefer_0576	4.905e-37	147.0	COG5016@1|root,arCOG02095@2157|Archaea,2XV3W@28890|Euryarchaeota,23Q4T@183939|Methanococci	183939|Methanococci	C	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158358_k127_766506_3	469383.Cwoe_3072	4.182e-66	236.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CPH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158358_k127_766506_2	1283299.AUKG01000004_gene940	2.069e-76	269.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CPI6@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158358_k127_766506_5	929712.KI912613_gene3456	8.872e-45	166.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158358_k127_766506_1	1122939.ATUD01000005_gene2634	8.368e-82	297.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158358_k127_766506_0	370438.PTH_1130	5.06e-108	361.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158358_k127_766506_4	1123227.KB899334_gene1790	5.43e-47	179.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,2JPBD@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158358_k127_774072_5	469383.Cwoe_1320	1.343e-19	90.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CQU8@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158358_k127_774072_7	929712.KI912613_gene4963	7.814e-07	57.0	COG0690@1|root,COG0690@2|Bacteria,2HQ1F@201174|Actinobacteria,4CRHK@84995|Rubrobacteria	84995|Rubrobacteria	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	-	-	-	-	-	-	-	-	-	SecE
SRR25158358_k127_774072_2	469383.Cwoe_1322	9.327e-69	237.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158358_k127_774072_3	469383.Cwoe_1323	1.02e-62	218.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4CQ3Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158358_k127_774072_1	469383.Cwoe_1324	6.47e-92	323.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158358_k127_774072_6	315730.BcerKBAB4_0094	1.398e-19	99.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158358_k127_774072_4	1088868.CIN_01590	1.111e-35	144.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2JSU1@204441|Rhodospirillales	204441|Rhodospirillales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158358_k127_774072_0	469383.Cwoe_1327	6.731e-111	364.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158358_k127_778365_3	469383.Cwoe_5282	2.615e-57	203.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158358_k127_778365_8	644966.Tmar_0248	2.066e-08	61.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,24JKA@186801|Clostridia	186801|Clostridia	O	TIGRFAM Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SRR25158358_k127_778365_9	644966.Tmar_0248	0.00014	47.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,24JKA@186801|Clostridia	186801|Clostridia	O	TIGRFAM Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SRR25158358_k127_778365_4	469383.Cwoe_2930	1.866e-54	211.0	COG2159@1|root,COG2159@2|Bacteria,2HJ7X@201174|Actinobacteria,4CPK2@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158358_k127_778365_6	1121448.DGI_3145	4.599e-40	171.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2M9BS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Molybdopterin dehydrogenase, FAD-binding	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158358_k127_778365_0	1128421.JAGA01000002_gene262	6.658e-181	591.0	COG1529@1|root,COG1529@2|Bacteria,2NPHP@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158358_k127_778365_5	1123368.AUIS01000019_gene1213	2.302e-43	163.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158358_k127_778365_1	1304880.JAGB01000004_gene1476	7.501e-134	441.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158358_k127_778365_2	309801.trd_1629	2.684e-116	387.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi,27XUE@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158358_k127_778365_7	1246484.D479_04183	1.142e-24	104.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,3NFY5@45667|Halobacillus	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
SRR25158358_k127_788061_8	298655.KI912266_gene1948	1.257e-29	121.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4ESV9@85013|Frankiales	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
SRR25158358_k127_788061_9	710696.Intca_3008	7.693e-12	76.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4FJUP@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158358_k127_788061_5	1396418.BATQ01000011_gene4478	1.716e-47	177.0	COG2197@1|root,COG2197@2|Bacteria,46V6C@74201|Verrucomicrobia,2IUHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158358_k127_788061_3	867903.ThesuDRAFT_02358	4.026e-66	236.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3WDHP@538999|Clostridiales incertae sedis	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158358_k127_788061_4	765420.OSCT_2658	4.153e-53	200.0	COG0491@1|root,COG0491@2|Bacteria,2G7QF@200795|Chloroflexi,375EQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158358_k127_788061_2	479434.Sthe_1848	1.247e-80	285.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158358_k127_788061_1	1128421.JAGA01000002_gene1223	5.123e-125	421.0	COG0247@1|root,COG0247@2|Bacteria,2NNU8@2323|unclassified Bacteria	2|Bacteria	C	Cysteine-rich domain	glcF	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	iAPECO1_1312.glcF,iECABU_c1320.ECABU_c33760,iECIAI1_1343.ECIAI1_3119,iECIAI39_1322.ECIAI39_3465,iECNA114_1301.ECNA114_3053,iECP_1309.ECP_3055,iJN678.glcF,iJN746.PP_3747,iUTI89_1310.glcF,ic_1306.glcF	CCG,Fer4_7,Fer4_8
SRR25158358_k127_788061_6	526225.Gobs_4800	1.358e-44	176.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4ETS6@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104,ko:K11472	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158358_k127_788061_0	525904.Tter_0160	5.367e-197	626.0	COG0277@1|root,COG0277@2|Bacteria,2NP2P@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750	FAD-oxidase_C,FAD_binding_4
SRR25158358_k127_788061_7	1227487.C474_16239	6.063e-37	143.0	COG0179@1|root,arCOG00235@2157|Archaea,2XT1S@28890|Euryarchaeota,23S3T@183963|Halobacteria	183963|Halobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158358_k127_78832_4	487796.Flav2ADRAFT_1178	1.43e-05	51.0	2EP9Y@1|root,33GWQ@2|Bacteria,4NZ2D@976|Bacteroidetes,1I6G5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_78832_1	455632.SGR_2680	4.644e-91	322.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,41C55@629295|Streptomyces griseus group	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158358_k127_78832_0	555079.Toce_0772	4.694e-292	917.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158358_k127_78832_2	397278.JOJN01000015_gene3468	1.503e-31	131.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4DRFZ@85009|Propionibacteriales	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158358_k127_78832_3	292459.STH473	1.382e-17	94.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158358_k127_788412_1	469383.Cwoe_3616	5.534e-74	260.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CP7V@84995|Rubrobacteria	84995|Rubrobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158358_k127_788412_0	1408254.T458_13050	1.984e-81	282.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,26T8K@186822|Paenibacillaceae	91061|Bacilli	C	(E1) component, eukaryotic type, alpha subunit	acoA	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
SRR25158358_k127_789226_2	469383.Cwoe_3773	2.021e-95	323.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CPF5@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158358_k127_789226_3	526226.Gbro_0408	6.569e-66	242.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4GA43@85026|Gordoniaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158358_k127_789226_0	469383.Cwoe_3774	3.426e-145	475.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158358_k127_789226_1	469383.Cwoe_3775	1.468e-125	421.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158358_k127_795120_0	1128421.JAGA01000004_gene2673	9.886e-179	570.0	COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
SRR25158358_k127_795120_8	1463900.JOIX01000025_gene5769	1.567e-21	107.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158358_k127_795120_4	67267.JNXT01000019_gene8070	2.006e-81	284.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	fbpC	-	-	ko:K02052,ko:K02062	ko02010,ko02024,map02010,map02024	M00191,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.19	-	-	ABC_tran,TOBE_2
SRR25158358_k127_795120_1	1210045.ALNP01000023_gene2929	1.114e-140	476.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	thiP	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1
SRR25158358_k127_795120_2	665577.JH993790_gene766	8.052e-112	376.0	COG4143@1|root,COG4143@2|Bacteria,2GMWD@201174|Actinobacteria	201174|Actinobacteria	H	ABC transporter, periplasmic binding protein, thiB subfamily	thiB	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
SRR25158358_k127_795120_7	926569.ANT_06690	4.355e-28	122.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158358_k127_795120_9	452863.Achl_3197	6.54e-21	107.0	COG1573@1|root,COG1573@2|Bacteria,2GRPK@201174|Actinobacteria	201174|Actinobacteria	L	uracil-dna glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158358_k127_795120_5	469383.Cwoe_1881	5.333e-58	204.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158358_k127_795120_6	1283299.AUKG01000001_gene3197	2.907e-43	164.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158358_k127_795120_3	264732.Moth_2246	2.986e-88	303.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,42EV8@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158358_k127_797201_2	224911.27355976	7.617e-54	197.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158358_k127_797201_1	933115.GPDM_06995	5.477e-83	285.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,26CZF@186818|Planococcaceae	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158358_k127_797201_0	1121946.AUAX01000052_gene8144	3.084e-97	337.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158358_k127_811511_1	1220582.RRU01S_07_03880	6.669e-88	297.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2TQQI@28211|Alphaproteobacteria,4BMSZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_811511_0	469383.Cwoe_5074	8.582e-149	494.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158358_k127_811511_2	1343740.M271_36090	7.07e-54	208.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158358_k127_811511_4	985053.VMUT_0023	1.175e-18	98.0	COG0596@1|root,arCOG01648@2157|Archaea,2XSA3@28889|Crenarchaeota	28889|Crenarchaeota	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158358_k127_811511_5	439235.Dalk_0219	8.04e-10	61.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158358_k127_811511_3	1382356.JQMP01000003_gene1716	2.213e-49	184.0	COG0154@1|root,COG0154@2|Bacteria,2G82J@200795|Chloroflexi,27XKT@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158358_k127_819455_6	1210046.B277_02938	6.34e-08	58.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158358_k127_819455_4	1123322.KB904674_gene2994	3.923e-20	98.0	COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,2GJ9M@201174|Actinobacteria	201174|Actinobacteria	V	Negative regulator of	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SLT
SRR25158358_k127_819455_0	1194972.MVAC_07446	9.747e-112	382.0	COG0212@1|root,COG0212@2|Bacteria,2I75G@201174|Actinobacteria,23FH6@1762|Mycobacteriaceae	201174|Actinobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_819455_1	648996.Theam_0948	3.934e-48	177.0	COG0537@1|root,COG0537@2|Bacteria,2G43E@200783|Aquificae	200783|Aquificae	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158358_k127_819455_5	58123.JOFJ01000011_gene4759	1.305e-18	94.0	COG1672@1|root,COG1672@2|Bacteria,2IGAA@201174|Actinobacteria,4EK0C@85012|Streptosporangiales	201174|Actinobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158358_k127_819455_3	1380356.JNIK01000015_gene2514	2.02e-39	160.0	COG3103@1|root,COG5479@1|root,COG4991@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4EX5K@85013|Frankiales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SRR25158358_k127_819455_2	557599.MKAN_01345	1.386e-42	166.0	COG0062@1|root,COG0062@2|Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158358_k127_819455_7	1120947.ATUX01000006_gene511	3.153e-05	47.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_821724_0	869210.Marky_1927	1.632e-109	369.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158358_k127_821724_2	1396418.BATQ01000171_gene2901	4.904e-27	124.0	COG0662@1|root,COG0662@2|Bacteria,46VA6@74201|Verrucomicrobia,2IVWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_821724_1	1463821.JOGR01000011_gene2286	1.71e-75	266.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4EXUT@85014|Glycomycetales	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158358_k127_833984_1	221288.JH992901_gene5747	5.323e-28	116.0	28KMN@1|root,2ZA61@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,TIR_2
SRR25158358_k127_833984_0	221288.JH992901_gene5748	1.626e-162	557.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158358_k127_846782_2	469383.Cwoe_3572	1.786e-47	177.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158358_k127_846782_1	266117.Rxyl_1658	2.204e-94	317.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158358_k127_846782_0	1245475.ANAE01000087_gene1183	3.017e-117	386.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria,4EFYU@85012|Streptosporangiales	201174|Actinobacteria	Q	Fumarylacetoacetase N-terminal	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158358_k127_85026_0	1313172.YM304_26780	3.198e-188	601.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158358_k127_85026_2	1120971.AUCA01000021_gene1029	4.086e-113	374.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,2781H@186823|Alicyclobacillaceae	91061|Bacilli	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158358_k127_85026_3	1120973.AQXL01000121_gene95	1.578e-63	227.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,278I2@186823|Alicyclobacillaceae	91061|Bacilli	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158358_k127_85026_1	469383.Cwoe_5326	1.037e-134	441.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria,4CPBH@84995|Rubrobacteria	84995|Rubrobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158358_k127_85026_4	1380390.JIAT01000010_gene4166	4.221e-18	86.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CPY7@84995|Rubrobacteria	84995|Rubrobacteria	K	Segregation and condensation complex subunit ScpB	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158358_k127_851725_1	264732.Moth_1700	2.696e-102	338.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,42F5U@68295|Thermoanaerobacterales	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158358_k127_851725_2	469383.Cwoe_3792	1.04e-37	147.0	2AW02@1|root,31MUH@2|Bacteria,2HQH7@201174|Actinobacteria,4CS2A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_851725_0	1283299.AUKG01000002_gene5233	1.575e-154	508.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158358_k127_852088_6	469383.Cwoe_2033	6.605e-83	276.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4CSHS@84995|Rubrobacteria	84995|Rubrobacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158358_k127_852088_9	266117.Rxyl_2743	8.144e-22	98.0	2BZXS@1|root,300MG@2|Bacteria,2HE2G@201174|Actinobacteria,4CTZP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_852088_5	266117.Rxyl_2744	2.908e-102	342.0	COG0523@1|root,COG0523@2|Bacteria,2GKDR@201174|Actinobacteria,4CQ83@84995|Rubrobacteria	84995|Rubrobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
SRR25158358_k127_852088_10	269799.Gmet_1509	3.707e-18	98.0	COG2606@1|root,COG2606@2|Bacteria,1NF5Q@1224|Proteobacteria,42WK9@68525|delta/epsilon subdivisions,2WS0A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158358_k127_852088_1	469383.Cwoe_5073	5.45e-186	597.0	COG1960@1|root,COG1960@2|Bacteria,2GNFB@201174|Actinobacteria,4CPM4@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_852088_2	994479.GL877879_gene5063	1.817e-162	523.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DXA8@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158358_k127_852088_4	675635.Psed_0101	2.672e-106	362.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E0R9@85010|Pseudonocardiales	201174|Actinobacteria	S	protein involved in propionate catabolism	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158358_k127_852088_7	1101188.KI912156_gene4127	1.237e-64	235.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,1W93S@1268|Micrococcaceae	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
SRR25158358_k127_852088_8	1101188.KI912156_gene4126	2.564e-60	218.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,1W8AM@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158358_k127_852088_3	330084.JNYZ01000034_gene2821	1.028e-112	373.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4E8IB@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_852088_0	1307436.PBF_16244	5.715e-200	633.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,1ZAQW@1386|Bacillus	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158358_k127_853408_0	469383.Cwoe_2836	2.599e-113	381.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158358_k127_853408_3	558173.CDOO_10325	1.793e-07	57.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,22NVQ@1653|Corynebacteriaceae	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158358_k127_853408_2	1122939.ATUD01000002_gene1413	2.855e-19	100.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158358_k127_853408_1	1380390.JIAT01000016_gene5648	4.006e-82	290.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4CPP2@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158358_k127_854749_4	867845.KI911784_gene145	4.666e-68	236.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158358_k127_854749_3	292459.STH1268	8.022e-74	265.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
SRR25158358_k127_854749_2	1077144.AGFF01000014_gene3003	2.482e-82	278.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158358_k127_854749_5	1183438.GKIL_1022	3.822e-46	182.0	COG0702@1|root,COG0702@2|Bacteria,1GHPI@1117|Cyanobacteria	1117|Cyanobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRR25158358_k127_854749_6	479434.Sthe_2553	6.685e-36	143.0	COG4122@1|root,COG4122@2|Bacteria,2G97D@200795|Chloroflexi,27Y9I@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158358_k127_854749_8	1380390.JIAT01000009_gene518	1.285e-30	130.0	COG2146@1|root,COG2146@2|Bacteria,2HPIQ@201174|Actinobacteria,4CQW9@84995|Rubrobacteria	84995|Rubrobacteria	P	Rieske 2Fe-2S iron-sulphur domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158358_k127_854749_7	1382356.JQMP01000003_gene2451	3.609e-33	141.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,27YGN@189775|Thermomicrobia	189775|Thermomicrobia	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158358_k127_854749_1	479434.Sthe_1525	1.259e-142	464.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,27Y1Z@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158358_k127_854749_0	469383.Cwoe_1723	8.732e-180	584.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CRWU@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPase (P-type)	-	-	3.6.3.8	ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158358_k127_858455_2	1500893.JQNB01000001_gene1615	1.118e-36	150.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158358_k127_858455_1	1229172.JQFA01000004_gene1163	8.615e-114	391.0	COG0464@1|root,COG0464@2|Bacteria,1G2M7@1117|Cyanobacteria,1HE1K@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158358_k127_858455_0	566466.NOR53_787	3.322e-141	456.0	COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria,1SKX1@1236|Gammaproteobacteria,1J932@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SRR25158358_k127_862216_5	1177594.MIC448_930010	1.453e-20	94.0	COG4177@1|root,COG4177@2|Bacteria,2IF69@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158358_k127_862216_2	1120949.KB903298_gene5764	4.941e-84	293.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158358_k127_862216_4	666686.B1NLA3E_09205	5.855e-29	132.0	COG0006@1|root,COG0006@2|Bacteria,1U9S2@1239|Firmicutes,4IJYE@91061|Bacilli,1ZP9G@1386|Bacillus	91061|Bacilli	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SRR25158358_k127_862216_0	404589.Anae109_4052	4.735e-86	290.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42ZH7@68525|delta/epsilon subdivisions,2WV12@28221|Deltaproteobacteria,2Z0K0@29|Myxococcales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158358_k127_862216_1	1242864.D187_009349	7.928e-86	307.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1R86D@1224|Proteobacteria	1224|Proteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,GSDH
SRR25158358_k127_862216_3	997346.HMPREF9374_1966	5.309e-46	190.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,27C0N@186824|Thermoactinomycetaceae	91061|Bacilli	O	Subtilase family	vpr	GO:0005575,GO:0005576	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,FlgD_ig,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5
SRR25158358_k127_867727_4	1267535.KB906767_gene1522	2.867e-22	107.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158358_k127_867727_5	1243664.CAVL020000016_gene1928	1.873e-17	95.0	COG0662@1|root,COG0662@2|Bacteria,1UB82@1239|Firmicutes,4IMKS@91061|Bacilli,1ZKDA@1386|Bacillus	91061|Bacilli	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_867727_3	1089546.AQUI01000002_gene1253	2.134e-30	135.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,408Y4@622450|Actinopolysporales	201174|Actinobacteria	I	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158358_k127_867727_0	309801.trd_1494	1.293e-111	374.0	COG0022@1|root,COG0022@2|Bacteria,2G84F@200795|Chloroflexi,27XW7@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158358_k127_867727_1	324602.Caur_3672	6.576e-108	370.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi,375G4@32061|Chloroflexia	32061|Chloroflexia	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
SRR25158358_k127_867727_2	177437.HRM2_47640	6.664e-51	191.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2MIUA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158358_k127_885872_0	469383.Cwoe_2633	8.496e-278	860.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158358_k127_885872_1	374847.Kcr_0796	4.588e-53	199.0	COG2423@1|root,arCOG01035@2157|Archaea	2157|Archaea	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	ala	-	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158358_k127_899512_3	1380390.JIAT01000009_gene2203	3.41e-16	92.0	COG2456@1|root,COG2456@2|Bacteria,2HR2A@201174|Actinobacteria,4CSX5@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
SRR25158358_k127_899512_2	1380390.JIAT01000009_gene2202	2.002e-66	241.0	COG1216@1|root,COG1216@2|Bacteria,2I2J1@201174|Actinobacteria,4CQYW@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158358_k127_899512_1	269797.Mbar_A0031	5.734e-89	307.0	arCOG07799@1|root,arCOG07799@2157|Archaea	2157|Archaea	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glycos_transf_2
SRR25158358_k127_899512_0	1283299.AUKG01000001_gene2234	3.999e-129	424.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CP93@84995|Rubrobacteria	84995|Rubrobacteria	GM	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158358_k127_902415_0	1122939.ATUD01000004_gene3946	3e-145	490.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158358_k127_902415_1	1187851.A33M_2337	3.738e-63	226.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,2U7N6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158358_k127_902415_2	1385519.N801_01750	9.195e-20	90.0	2BG65@1|root,32A2Y@2|Bacteria,2IRVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_903454_0	1121878.AUGL01000010_gene1030	7.685e-86	300.0	COG1215@1|root,COG1215@2|Bacteria,1MY6I@1224|Proteobacteria,1SKXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158358_k127_903454_1	469383.Cwoe_3190	3.584e-45	171.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158358_k127_905813_1	1206101.AZXC01000009_gene515	7.719e-51	187.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158358_k127_905813_2	590998.Celf_2768	0.0004865	51.0	2ANYB@1|root,2ZUQD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_905813_0	929712.KI912613_gene3402	1.372e-153	490.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4CR27@84995|Rubrobacteria	84995|Rubrobacteria	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158358_k127_907419_3	586416.GZ22_02460	5.944e-53	193.0	COG1335@1|root,COG1335@2|Bacteria,1VA32@1239|Firmicutes,4HKVT@91061|Bacilli	91061|Bacilli	Q	Isochorismatase family	-	-	3.5.1.107	ko:K13995	ko00760,ko01120,map00760,map01120	M00622	R03540	RC00950	ko00000,ko00001,ko00002,ko01000	-	-	-	Isochorismatase
SRR25158358_k127_907419_4	869210.Marky_1921	1.426e-36	144.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158358_k127_907419_0	479434.Sthe_3474	2.171e-114	389.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158358_k127_907419_6	68260.JOAY01000006_gene5077	3.377e-10	67.0	COG1649@1|root,COG1649@2|Bacteria,2GMQ6@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_907419_2	1089544.KB912942_gene1307	5.633e-57	209.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4DXV2@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158358_k127_907419_1	1123023.JIAI01000001_gene7529	8.962e-78	280.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4EBE5@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158358_k127_907419_5	1198449.ACAM_0027	1.303e-15	82.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158358_k127_907763_3	1121468.AUBR01000008_gene2057	8.883e-47	172.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,42GWU@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158358_k127_907763_4	196162.Noca_3252	1.223e-16	86.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4DR0E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158358_k127_907763_0	1121346.KB899824_gene3026	8.697e-79	278.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158358_k127_907763_1	1401067.HMPREF0872_05755	4.804e-61	224.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158358_k127_907763_2	521098.Aaci_0208	8.372e-51	185.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,278AX@186823|Alicyclobacillaceae	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158358_k127_907763_5	1122939.ATUD01000002_gene1184	8.617e-08	57.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158358_k127_91179_2	1458427.BAWN01000031_gene1760	0.0001561	44.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	Lactamase_B,NUDIX
SRR25158358_k127_91179_1	1205753.A989_17583	1.567e-33	140.0	COG3595@1|root,COG3595@2|Bacteria,1RI1P@1224|Proteobacteria,1RRZW@1236|Gammaproteobacteria,1X68A@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158358_k127_91179_0	867845.KI911784_gene3056	5.52e-200	644.0	COG1770@1|root,COG1770@2|Bacteria,2G694@200795|Chloroflexi,3770C@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158358_k127_913706_1	1380390.JIAT01000009_gene457	1.939e-46	184.0	COG4102@1|root,COG4102@2|Bacteria,2GJWB@201174|Actinobacteria,4CS10@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158358_k127_913706_0	469383.Cwoe_1102	3.517e-71	268.0	COG5267@1|root,COG5267@2|Bacteria,2I8YT@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158358_k127_913706_2	1429046.RR21198_1746	2.572e-25	117.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,4G05E@85025|Nocardiaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158358_k127_916620_1	285514.JNWO01000008_gene2745	1.155e-05	48.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158358_k127_928378_0	1150469.RSPPHO_02178	1.207e-272	852.0	COG0069@1|root,COG2218@1|root,COG0069@2|Bacteria,COG2218@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria,2JQUP@204441|Rhodospirillales	204441|Rhodospirillales	E	IMP dehydrogenase / GMP reductase domain	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
SRR25158358_k127_928378_1	886293.Sinac_0841	3.46e-45	169.0	COG0034@1|root,COG0034@2|Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	glxB	-	2.1.1.21	ko:K22081	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GATase_6
SRR25158358_k127_93047_0	309801.trd_0562	3.955e-261	840.0	COG0567@1|root,COG0567@2|Bacteria,2G638@200795|Chloroflexi,27XYT@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158358_k127_930821_6	1232410.KI421424_gene1795	2.493e-78	269.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	pgmB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576	2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6	ko:K01087,ko:K01194,ko:K01838,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R02778,R11310	RC00017,RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
SRR25158358_k127_930821_0	1038860.AXAP01000015_gene2096	1.486e-264	850.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,2U1CG@28211|Alphaproteobacteria,3JWWP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	-	-	2.4.1.64,5.4.2.6	ko:K01838,ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SRR25158358_k127_930821_7	335541.Swol_1229	6.482e-48	179.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,42JY3@68298|Syntrophomonadaceae	186801|Clostridia	S	Putative neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
SRR25158358_k127_930821_4	526225.Gobs_0698	4.339e-110	368.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4ETXZ@85013|Frankiales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158358_k127_930821_1	1380390.JIAT01000009_gene442	2.697e-153	497.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CPTP@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158358_k127_930821_8	1497679.EP56_04020	2.342e-29	135.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,26JIK@186820|Listeriaceae	91061|Bacilli	P	copper export	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,YtkA
SRR25158358_k127_930821_9	768671.ThimaDRAFT_4676	3.243e-29	122.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158358_k127_930821_2	1173028.ANKO01000174_gene2711	2.365e-142	488.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1HEHF@1150|Oscillatoriales	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158358_k127_930821_5	1380390.JIAT01000009_gene2076	2.259e-81	303.0	COG3605@1|root,COG3835@1|root,COG3605@2|Bacteria,COG3835@2|Bacteria,2I7AB@201174|Actinobacteria,4CQ23@84995|Rubrobacteria	84995|Rubrobacteria	QT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_30
SRR25158358_k127_930821_3	1123507.ATVQ01000001_gene1317	2.516e-142	466.0	COG0174@1|root,COG0174@2|Bacteria,2GK8A@201174|Actinobacteria,1W8DP@1268|Micrococcaceae	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnT	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158358_k127_934797_5	1144275.COCOR_04132	4.344e-07	63.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158358_k127_934797_2	1122939.ATUD01000005_gene2553	1.531e-43	168.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CQNN@84995|Rubrobacteria	84995|Rubrobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158358_k127_934797_1	1283299.AUKG01000006_gene795	1.185e-85	293.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria	84995|Rubrobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158358_k127_934797_4	1229780.BN381_60087	1.183e-27	119.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HTH_Crp_2,cNMP_binding
SRR25158358_k127_934797_3	331869.BAL199_16693	2.859e-39	152.0	COG0346@1|root,COG0346@2|Bacteria,1RIUN@1224|Proteobacteria,2U9CD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158358_k127_934797_0	469383.Cwoe_3606	1.201e-99	336.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CP98@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158358_k127_940317_3	1121380.JNIW01000017_gene2948	6.661e-08	64.0	COG0457@1|root,COG0457@2|Bacteria	1121380.JNIW01000017_gene2948|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_940317_1	469383.Cwoe_4202	6.684e-36	149.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_940317_0	1283299.AUKG01000001_gene3253	3.014e-115	379.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4CRTQ@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese-like domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158358_k127_940317_2	1089544.KB912942_gene4160	4.953e-25	108.0	COG0300@1|root,COG0300@2|Bacteria,2IG6H@201174|Actinobacteria,4E4ZK@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158358_k127_94116_2	1248917.ANFX01000025_gene1269	2.631e-19	104.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2K3VU@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158358_k127_94116_1	1229780.BN381_150140	4.714e-42	172.0	COG0477@1|root,COG0477@2|Bacteria,2I607@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3
SRR25158358_k127_94116_0	710111.FraQA3DRAFT_5145	5.624e-213	674.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4ES4C@85013|Frankiales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158358_k127_941382_1	926561.KB900622_gene598	2.673e-50	187.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WAGY@53433|Halanaerobiales	186801|Clostridia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158358_k127_941382_0	1121422.AUMW01000002_gene2198	2.804e-100	338.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158358_k127_941382_2	1123239.KB898626_gene677	8.203e-49	178.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158358_k127_941382_3	644966.Tmar_0414	1.452e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158358_k127_942203_8	1211815.CBYP010000062_gene3178	2.135e-17	83.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158358_k127_942203_7	525904.Tter_2084	4.017e-30	124.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	CBS
SRR25158358_k127_942203_5	33876.JNXY01000016_gene7115	4.982e-65	229.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4DC3H@85008|Micromonosporales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158358_k127_942203_1	525904.Tter_0014	2.214e-140	460.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158358_k127_942203_3	1137271.AZUM01000008_gene2090	5.015e-82	284.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158358_k127_942203_9	331869.BAL199_03499	3.64e-06	58.0	COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria,2U4IR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_942203_0	1283283.ATXA01000001_gene977	1.864e-147	477.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4ES0F@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158358_k127_942203_4	227882.SAV_6283	2.175e-79	275.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria	201174|Actinobacteria	ET	ABC transporter substrate-binding protein	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
SRR25158358_k127_942203_2	479432.Sros_9352	3.849e-88	299.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4EGKS@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,DUF2808,SBP_bac_3
SRR25158358_k127_942203_6	469371.Tbis_3555	2.858e-44	164.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4E109@85010|Pseudonocardiales	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158358_k127_94493_5	1380390.JIAT01000010_gene4890	9.791e-44	172.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158358_k127_94493_6	1127696.HMPREF9134_00606	5.001e-13	74.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,2FTXK@200643|Bacteroidia,22YDB@171551|Porphyromonadaceae	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158358_k127_94493_0	1382304.JNIL01000001_gene1065	2.4e-114	380.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,27827@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158358_k127_94493_1	266117.Rxyl_1329	8.62e-93	317.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158358_k127_94493_4	1121472.AQWN01000004_gene754	4.635e-51	199.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158358_k127_94493_3	555088.DealDRAFT_0002	7.851e-67	237.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,42KCR@68298|Syntrophomonadaceae	186801|Clostridia	K	response regulator receiver	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158358_k127_94493_2	671143.DAMO_1527	2.988e-90	307.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158358_k127_94493_7	266117.Rxyl_1020	3.076e-12	72.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CS0G@84995|Rubrobacteria	201174|Actinobacteria	P	Arsenical pump membrane protein	arsA	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
SRR25158358_k127_948696_7	1206726.BAFV01000040_gene2927	7.747e-17	81.0	COG1028@1|root,COG1028@2|Bacteria,2IPDV@201174|Actinobacteria,4FZ4P@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158358_k127_948696_5	929712.KI912613_gene623	6.672e-47	179.0	COG0251@1|root,COG0251@2|Bacteria,2HPBX@201174|Actinobacteria,4CTSQ@84995|Rubrobacteria	84995|Rubrobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158358_k127_948696_0	84531.JMTZ01000030_gene181	1.194e-107	357.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,1RSGE@1236|Gammaproteobacteria,1X4EY@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158358_k127_948696_2	1123242.JH636436_gene255	1.169e-67	241.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158358_k127_948696_3	414684.RC1_1347	3.739e-60	219.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,2JR0K@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158358_k127_948696_4	653045.Strvi_3892	4.942e-55	207.0	28I63@1|root,2Z897@2|Bacteria,2H8CP@201174|Actinobacteria	201174|Actinobacteria	S	Amino acid synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AA_synth
SRR25158358_k127_948696_6	420324.KI912020_gene7506	1.37e-23	111.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria,1JWGR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158358_k127_948696_1	1463887.KL589992_gene377	1.575e-90	307.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknJ	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158358_k127_9494_2	1122939.ATUD01000005_gene2648	5.925e-91	319.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CPSV@84995|Rubrobacteria	84995|Rubrobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158358_k127_9494_0	743719.PaelaDRAFT_5986	7.293e-227	715.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158358_k127_9494_1	469383.Cwoe_3087	5.818e-98	332.0	COG2195@1|root,COG2195@2|Bacteria,2HPTW@201174|Actinobacteria,4CR7V@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158358_k127_9494_4	867903.ThesuDRAFT_00096	9.354e-17	93.0	COG3502@1|root,COG3502@2|Bacteria,1TQW1@1239|Firmicutes,24952@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158358_k127_9494_3	1149133.ppKF707_2527	3.478e-24	116.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1YIRX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158358_k127_951632_1	1323361.JPOC01000007_gene446	3.085e-32	129.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4FUUT@85025|Nocardiaceae	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158358_k127_951632_0	500635.MITSMUL_05308	1.049e-162	522.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158358_k127_951632_2	1121346.KB899816_gene3239	0.0003605	50.0	2DQT5@1|root,338GV@2|Bacteria,1VEES@1239|Firmicutes,4HNWP@91061|Bacilli	91061|Bacilli	-	-	M1-488	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_954642_1	1380390.JIAT01000016_gene5629	1.856e-16	83.0	COG0791@1|root,COG0791@2|Bacteria,2HPJC@201174|Actinobacteria,4CQWT@84995|Rubrobacteria	84995|Rubrobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158358_k127_954642_0	1122223.KB890688_gene1647	5.648e-251	789.0	COG1012@1|root,COG1012@2|Bacteria,1WJFH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158358_k127_964008_3	1111479.AXAR01000020_gene1224	2.504e-16	91.0	COG0697@1|root,COG0697@2|Bacteria,1V65P@1239|Firmicutes,4HKKD@91061|Bacilli	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158358_k127_964008_0	1121946.AUAX01000052_gene8144	2.608e-155	530.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158358_k127_964008_2	1380390.JIAT01000014_gene6100	7.645e-125	413.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CPB0@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158358_k127_964008_6	1463861.JNXE01000008_gene9573	0.0008813	49.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158358_k127_964008_1	1313301.AUGC01000006_gene67	3.371e-140	456.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158358_k127_964008_4	1292034.OR37_00318	6.113e-13	76.0	COG4359@1|root,COG4359@2|Bacteria,1REUD@1224|Proteobacteria,2U9HY@28211|Alphaproteobacteria,2KIK0@204458|Caulobacterales	204458|Caulobacterales	E	Putative Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158358_k127_964806_2	882083.SacmaDRAFT_2677	1.8e-136	442.0	COG0761@1|root,COG0775@1|root,COG0761@2|Bacteria,COG0775@2|Bacteria,2GIZ7@201174|Actinobacteria,4DZDW@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,PNP_UDP_1
SRR25158358_k127_964806_1	351607.Acel_1699	9.339e-169	546.0	COG0535@1|root,COG0535@2|Bacteria,2HTDD@201174|Actinobacteria,4ES4M@85013|Frankiales	201174|Actinobacteria	F	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
SRR25158358_k127_964806_3	1120936.KB907221_gene2143	4.113e-70	245.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,4EN6P@85012|Streptosporangiales	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158358_k127_964806_0	1283299.AUKG01000002_gene4290	9.202e-190	604.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158358_k127_967269_1	469383.Cwoe_4683	1.861e-93	329.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_967269_2	867903.ThesuDRAFT_00741	1.185e-81	282.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WCCM@538999|Clostridiales incertae sedis	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158358_k127_967269_7	1121406.JAEX01000047_gene2736	6.927e-08	63.0	COG0449@1|root,COG0449@2|Bacteria,1R77V@1224|Proteobacteria,42P01@68525|delta/epsilon subdivisions,2WKJE@28221|Deltaproteobacteria,2M9CY@213115|Desulfovibrionales	1224|Proteobacteria	M	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6
SRR25158358_k127_967269_6	416348.Hlac_2975	2.256e-10	72.0	arCOG08099@1|root,arCOG08099@2157|Archaea,2Y8AQ@28890|Euryarchaeota,2417K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_967269_0	469383.Cwoe_3270	1.012e-139	458.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158358_k127_967269_4	469383.Cwoe_3272	3.247e-69	244.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CPRV@84995|Rubrobacteria	84995|Rubrobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158358_k127_967269_3	253839.SSNG_07403	6.163e-78	266.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158358_k127_975081_3	469383.Cwoe_1983	4.326e-42	165.0	COG0400@1|root,COG0400@2|Bacteria,2GZKY@201174|Actinobacteria,4CPVW@84995|Rubrobacteria	84995|Rubrobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158358_k127_975081_0	469383.Cwoe_4746	1.289e-125	408.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158358_k127_975081_2	469383.Cwoe_4525	9.596e-43	160.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4CQGU@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158358_k127_975081_1	266117.Rxyl_2620	4.711e-71	254.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CPA3@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,LPG_synthase_TM
SRR25158358_k127_975196_5	469383.Cwoe_0292	1.742e-25	115.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CRHZ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158358_k127_975196_2	469383.Cwoe_0293	6.879e-100	334.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CPYK@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158358_k127_975196_9	935866.JAER01000002_gene1937	5.411e-09	63.0	2EQ52@1|root,33HRD@2|Bacteria,2IPDK@201174|Actinobacteria,4DRHU@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_2
SRR25158358_k127_975196_1	518766.Rmar_1488	1.507e-108	361.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158358_k127_975196_4	272557.APE_2507.1	1.775e-51	195.0	COG0111@1|root,arCOG01754@2157|Archaea,2XRM3@28889|Crenarchaeota	28889|Crenarchaeota	H	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158358_k127_975196_8	314264.ROS217_07645	8.112e-15	78.0	arCOG10157@1|root,3220G@2|Bacteria,1N33N@1224|Proteobacteria,2UCKN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methylmuconolactone methyl-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MmlI
SRR25158358_k127_975196_3	1206730.BAGA01000077_gene1077	2.083e-53	205.0	29KBT@1|root,30793@2|Bacteria,2IE0E@201174|Actinobacteria,4G71Y@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_AC39
SRR25158358_k127_975196_0	55952.BU52_26000	5.562e-115	390.0	COG1269@1|root,COG1269@2|Bacteria,2I9VH@201174|Actinobacteria	201174|Actinobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158358_k127_975196_6	1172179.AUKV01000005_gene6017	1.878e-24	108.0	COG0636@1|root,COG0636@2|Bacteria,2IS0Q@201174|Actinobacteria	201174|Actinobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158358_k127_975196_10	55952.BU52_25990	2.829e-07	57.0	COG1436@1|root,COG1436@2|Bacteria,2I80G@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_975196_7	284031.JNXD01000003_gene3713	1.115e-16	86.0	COG1390@1|root,COG1390@2|Bacteria,2GT2F@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
SRR25158358_k127_975196_11	1449976.KALB_4145	0.0002472	52.0	COG1155@1|root,COG1155@2|Bacteria,2HESQ@201174|Actinobacteria,4DYJN@85010|Pseudonocardiales	201174|Actinobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SRR25158358_k127_979157_1	1121946.AUAX01000005_gene5339	2.721e-105	354.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4D8CT@85008|Micromonosporales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158358_k127_979157_0	1122939.ATUD01000009_gene3014	9.169e-113	376.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CPAI@84995|Rubrobacteria	84995|Rubrobacteria	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158358_k127_979157_3	1550073.JROH01000012_gene2527	7.445e-07	57.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U7GY@28211|Alphaproteobacteria,2KCC3@204457|Sphingomonadales	204457|Sphingomonadales	NU	Type II secretion system (T2SS), protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158358_k127_979157_2	1380390.JIAT01000009_gene840	7.087e-45	166.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4CQ49@84995|Rubrobacteria	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158358_k127_979294_1	1122939.ATUD01000007_gene2023	1.117e-18	90.0	COG0662@1|root,COG0662@2|Bacteria,2GZ5U@201174|Actinobacteria,4CSXN@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158358_k127_979294_4	388399.SSE37_19807	6.704e-05	57.0	COG1196@1|root,COG1360@1|root,COG1196@2|Bacteria,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2TQKZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SRR25158358_k127_979294_3	443143.GM18_1659	9.176e-08	67.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347,HemolysinCabind,Phosphoesterase,VCBS,fn3
SRR25158358_k127_979294_0	1122939.ATUD01000003_gene3633	2.524e-47	177.0	2AV0E@1|root,31KQ8@2|Bacteria,2HPHG@201174|Actinobacteria,4CQVP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_979294_2	42256.RradSPS_0596	3.052e-15	79.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4CQQK@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158358_k127_980955_0	706587.Desti_1404	3.143e-106	363.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
SRR25158358_k127_980955_1	46234.ANA_C11360	1.296e-18	96.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HNFR@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158358_k127_990315_3	446468.Ndas_0553	2.155e-57	213.0	COG2186@1|root,COG2186@2|Bacteria,2GTZ3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158358_k127_990315_4	484770.UFO1_4667	2.407e-48	184.0	COG0329@1|root,COG0329@2|Bacteria,1TPSG@1239|Firmicutes,4H3JN@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158358_k127_990315_2	1123229.AUBC01000005_gene606	9.143e-83	292.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,3JSMG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	MA20_16265	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158358_k127_990315_0	1123023.JIAI01000008_gene1459	1.95e-113	382.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158358_k127_990315_5	318586.Pden_3491	7.498e-40	160.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TVZ2@28211|Alphaproteobacteria,2PZ9T@265|Paracoccus	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	pcaD	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,CMD
SRR25158358_k127_990315_7	1122182.KB903821_gene1273	7.859e-10	65.0	2B3DA@1|root,31W23@2|Bacteria,2INNH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158358_k127_990315_6	489825.LYNGBM3L_54410	4.93e-25	111.0	COG0432@1|root,COG0432@2|Bacteria,1G5WN@1117|Cyanobacteria,1HB6T@1150|Oscillatoriales	1117|Cyanobacteria	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158358_k127_990315_1	42256.RradSPS_2748	9.704e-84	281.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CPC2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
## 2270 queries scanned
## Total time (seconds): 3.267641305923462
## Rate: 694.69 q/s