## Sun Dec 14 23:09:15 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158380_bin.10.fa -m mmseqs --itype genome -o SRR25158380_bin.10 --output_dir /data/result/bins/wyx/egg/SRR25158380_bin.10 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158380_k127_1000475_2	745776.DGo_CA0722	1.334e-19	98.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_26
SRR25158380_k127_1000475_0	452637.Oter_4283	1.14e-285	898.0	COG0657@1|root,COG0657@2|Bacteria,46TU9@74201|Verrucomicrobia,3KA3K@414999|Opitutae	414999|Opitutae	I	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
SRR25158380_k127_1000475_1	518766.Rmar_2605	2.526e-21	96.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
SRR25158380_k127_1003075_3	493475.GARC_4550	1.15e-26	128.0	COG1506@1|root,COG2374@1|root,COG1506@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,46500@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Extracellular nuclease	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Endonuclease_1,Exo_endo_phos,LTD
SRR25158380_k127_1003075_2	1163407.UU7_07288	1.048e-28	135.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
SRR25158380_k127_1003075_1	3988.XP_002536490.1	1.391e-48	200.0	COG2374@1|root,2QV0U@2759|Eukaryota,382YS@33090|Viridiplantae	33090|Viridiplantae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1003075_6	402881.Plav_0041	0.0003245	49.0	2EHKJ@1|root,33BCB@2|Bacteria,1Q48W@1224|Proteobacteria,2UMI4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4282
SRR25158380_k127_1003075_5	1278073.MYSTI_07271	1.248e-06	57.0	2DR66@1|root,33ACE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1003075_0	1340493.JNIF01000003_gene2305	1.409e-98	329.0	COG2022@1|root,COG2022@2|Bacteria,3Y2YY@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158380_k127_1003075_4	398767.Glov_0035	3.459e-14	74.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2WSM2@28221|Deltaproteobacteria,43VNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158380_k127_100792_3	1183438.GKIL_4354	7.763e-45	169.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_100792_0	251221.35211765	8.045e-226	726.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_100792_1	1267535.KB906767_gene630	2.443e-107	351.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria,2JHYU@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158380_k127_100792_2	1267535.KB906767_gene632	3.455e-85	285.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_1009488_1	661478.OP10G_2288	7.339e-59	218.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
SRR25158380_k127_1009488_0	671143.DAMO_0095	2.442e-161	520.0	COG1282@1|root,COG1282@2|Bacteria,2NQMF@2323|unclassified Bacteria	2|Bacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158380_k127_1009488_2	671143.DAMO_0094	2.018e-34	134.0	COG3288@1|root,COG3288@2|Bacteria,2NRJW@2323|unclassified Bacteria	2|Bacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158380_k127_1009488_3	388413.ALPR1_14899	5.972e-13	70.0	2DBTJ@1|root,2ZAYX@2|Bacteria,4NKRB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1011315_9	1033730.CAHG01000012_gene2379	7.61e-26	111.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DMZ6@85009|Propionibacteriales	201174|Actinobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158380_k127_1011315_7	398767.Glov_3258	2.72e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158380_k127_1011315_11	1476973.JMMB01000007_gene3240	9.062e-22	109.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158380_k127_1011315_5	869210.Marky_1204	2.279e-69	244.0	COG0491@1|root,COG0491@2|Bacteria,1WISH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_1011315_1	1267535.KB906767_gene5475	4.432e-126	409.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158380_k127_1011315_2	469383.Cwoe_1095	1.533e-109	364.0	COG0524@1|root,COG0524@2|Bacteria,2HPJD@201174|Actinobacteria,4CQWU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158380_k127_1011315_12	1499967.BAYZ01000036_gene2434	7.006e-09	62.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158380_k127_1011315_8	869210.Marky_1021	1.578e-27	115.0	COG1324@1|root,COG1324@2|Bacteria,1WKG6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158380_k127_1011315_4	886293.Sinac_1893	1.666e-83	284.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158380_k127_1011315_3	1382359.JIAL01000001_gene1578	6.001e-96	320.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_1011315_6	1499967.BAYZ01000147_gene731	1.537e-56	213.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158380_k127_1011315_10	864702.OsccyDRAFT_2580	6.957e-22	102.0	COG3409@1|root,COG3409@2|Bacteria,1GR82@1117|Cyanobacteria,1HIA0@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1011315_0	556268.OFAG_01432	4.245e-128	421.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,473U8@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158380_k127_1014937_0	1267533.KB906733_gene2973	3.127e-34	152.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria	57723|Acidobacteria	KU	WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158380_k127_1017632_3	1158338.JNLJ01000005_gene1540	2.525e-111	370.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,2G3J0@200783|Aquificae	200783|Aquificae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158380_k127_1017632_1	1144275.COCOR_05413	5.107e-149	490.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria	1224|Proteobacteria	U	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158380_k127_1017632_5	1487923.DP73_09090	2.768e-69	241.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25ZXN@186807|Peptococcaceae	186801|Clostridia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158380_k127_1017632_4	246194.CHY_1283	9.6e-110	368.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,42FR9@68295|Thermoanaerobacterales	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158380_k127_1017632_6	1379698.RBG1_1C00001G0228	7.795e-63	226.0	COG0846@1|root,COG0846@2|Bacteria,2NPJR@2323|unclassified Bacteria	2|Bacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158380_k127_1017632_0	1267535.KB906767_gene1458	4.278e-194	628.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158380_k127_1017632_2	240015.ACP_2753	1.537e-141	458.0	COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158380_k127_1017632_7	1122939.ATUD01000012_gene3147	0.0003561	48.0	2B8XJ@1|root,32280@2|Bacteria,2HRTD@201174|Actinobacteria,4CTWV@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1021102_4	945713.IALB_1465	4.056e-74	256.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158380_k127_1021102_1	1207055.C100_11150	6.898e-129	423.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K16D@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_1021102_3	479434.Sthe_0531	4.18e-89	306.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	2|Bacteria	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_1021102_5	1120973.AQXL01000134_gene1599	2.508e-73	255.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG_4	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_1021102_0	644966.Tmar_1343	2.133e-166	540.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158380_k127_1021102_2	1382306.JNIM01000001_gene3887	1.945e-108	357.0	COG1028@1|root,COG1028@2|Bacteria	1382306.JNIM01000001_gene3887|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1022780_0	234267.Acid_1582	0.0	1032.0	COG2936@1|root,COG2936@2|Bacteria,3Y684@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158380_k127_1022780_2	187303.BN69_1560	3.271e-19	89.0	COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,2UGAG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158380_k127_1022780_1	572477.Alvin_0648	3.802e-25	106.0	COG1598@1|root,COG1598@2|Bacteria,1NBIX@1224|Proteobacteria,1SCV3@1236|Gammaproteobacteria,1WZ6M@135613|Chromatiales	135613|Chromatiales	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158380_k127_1022780_3	1298867.AUES01000056_gene4770	0.0002294	44.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2UPFX@28211|Alphaproteobacteria,3K3BH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	5.3.3.7	ko:K22003	ko00660,map00660	-	R02244	RC00668	ko00000,ko00001,ko01000	-	-	-	SBP_bac_11
SRR25158380_k127_1023924_0	401053.AciPR4_0212	8.477e-124	430.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Y@57723|Acidobacteria,2JKVG@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1023924_3	1408324.JNJK01000010_gene2171	1.877e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24HT2@186801|Clostridia,27IN2@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158380_k127_1023924_1	469617.FUAG_02984	8.144e-95	325.0	COG2304@1|root,COG2304@2|Bacteria,37BRZ@32066|Fusobacteria	32066|Fusobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158380_k127_1023924_2	1267535.KB906767_gene2786	5.046e-26	113.0	2DB97@1|root,32TX2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1030253_1	1267535.KB906767_gene2344	5.927e-86	296.0	COG0577@1|root,COG0577@2|Bacteria,3Y67P@57723|Acidobacteria,2JKNB@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1030253_0	234267.Acid_3798	5.093e-179	589.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_3798|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1030253_2	234267.Acid_7177	2.643e-62	224.0	COG0577@1|root,COG0577@2|Bacteria,3Y402@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1037663_0	700598.Niako_1650	5.583e-198	638.0	28K9B@1|root,2Z9WY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1037663_1	411477.PARMER_02725	2.032e-100	350.0	2DBP8@1|root,2ZA84@2|Bacteria,4NKHW@976|Bacteroidetes,2FQDJ@200643|Bacteroidia,22ZNZ@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1041058_2	2002.JOEQ01000059_gene1510	3.96e-67	237.0	COG2232@1|root,COG2232@2|Bacteria,2I3K8@201174|Actinobacteria,4ER3A@85012|Streptosporangiales	201174|Actinobacteria	S	ATP-grasp domain	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-grasp_4
SRR25158380_k127_1041058_0	47716.JOFH01000027_gene2909	5.071e-120	394.0	COG0031@1|root,COG0031@2|Bacteria,2GK6J@201174|Actinobacteria	201174|Actinobacteria	E	cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_1041058_1	73044.JNXP01000002_gene1885	8.449e-72	252.0	COG4542@1|root,COG4542@2|Bacteria,2I8UM@201174|Actinobacteria	201174|Actinobacteria	Q	COG4542 Protein involved in propanediol utilization, and related proteins includes coumermycin biosynthetic protein	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_104816_2	485913.Krac_5098	3.097e-29	120.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_104816_1	317936.Nos7107_4910	6.113e-72	250.0	COG4894@1|root,COG4894@2|Bacteria,1G3DI@1117|Cyanobacteria,1HIUP@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_104816_0	204669.Acid345_4390	1.074e-96	334.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_1049667_1	714313.LSA_11430	3.433e-146	490.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae	91061|Bacilli	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158380_k127_1049667_0	644968.DFW101_2241	8.885e-222	699.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2M84Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158380_k127_1049667_2	580340.Tlie_1351	2.767e-18	93.0	COG0576@1|root,COG0576@2|Bacteria,3TBD9@508458|Synergistetes	508458|Synergistetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158380_k127_1060247_3	215803.DB30_6572	6.882e-38	153.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria,439DU@68525|delta/epsilon subdivisions,2X4NR@28221|Deltaproteobacteria,2YZBD@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
SRR25158380_k127_1060247_2	215803.DB30_6573	3.68e-43	169.0	2DBRJ@1|root,2ZAMD@2|Bacteria,1R498@1224|Proteobacteria,438U5@68525|delta/epsilon subdivisions,2X40B@28221|Deltaproteobacteria,2YXSK@29|Myxococcales	28221|Deltaproteobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR25158380_k127_1060247_1	1121035.AUCH01000005_gene9	2.595e-49	184.0	2DK2X@1|root,3089T@2|Bacteria,1RF89@1224|Proteobacteria,2VR56@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1060247_0	1121920.AUAU01000001_gene2169	9.825e-60	215.0	2919Q@1|root,32TZW@2|Bacteria,3Y5IU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1060247_4	1123053.AUDG01000002_gene2818	5.182e-33	139.0	2CD3D@1|root,32RWZ@2|Bacteria,1N61G@1224|Proteobacteria,1SB8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_1062288_0	204669.Acid345_1678	0.0	1017.0	COG4932@1|root,COG4932@2|Bacteria,3Y98G@57723|Acidobacteria,2JP50@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1081456_2	861299.J421_0909	5.088e-22	102.0	COG2940@1|root,COG2940@2|Bacteria,1ZTR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158380_k127_1081456_1	671143.DAMO_2827	1.832e-76	260.0	COG3260@1|root,COG3260@2|Bacteria,2NRM4@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hycG	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
SRR25158380_k127_1081456_0	330214.NIDE4265	5.498e-140	460.0	COG0651@1|root,COG0651@2|Bacteria,3J0HR@40117|Nitrospirae	40117|Nitrospirae	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
SRR25158380_k127_1096252_2	861299.J421_0248	0.0001147	45.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUXK@142182|Gemmatimonadetes	2|Bacteria	T	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
SRR25158380_k127_1096252_1	1267534.KB906760_gene1549	1.012e-07	56.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158380_k127_1097151_1	319225.Plut_0333	1.341e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1FE3I@1090|Chlorobi	1090|Chlorobi	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_1097151_0	1128421.JAGA01000002_gene1062	6.405e-09	67.0	COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria	2|Bacteria	A	pathogenesis	CP_0034	-	-	ko:K02417,ko:K02519	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03012,ko03029	3.A.6.2,3.A.6.3	-	-	GPDPase_memb
SRR25158380_k127_1097151_2	1121335.Clst_2266	0.0002346	53.0	2BZCW@1|root,32R4U@2|Bacteria,1V7B7@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158380_k127_1097151_3	1121090.KB894689_gene314	0.0006895	50.0	28I6X@1|root,2Z89S@2|Bacteria,1TQMI@1239|Firmicutes,4HD5B@91061|Bacilli,1ZD3B@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158380_k127_1103247_2	204669.Acid345_1842	3.953e-26	120.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1103247_0	1382304.JNIL01000001_gene614	7.694e-144	469.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,277XV@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158380_k127_1103247_1	1340493.JNIF01000003_gene1803	4.127e-35	148.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SRR25158380_k127_1106537_0	1123371.ATXH01000003_gene1979	8.392e-160	509.0	COG0137@1|root,COG0137@2|Bacteria,2GGZY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158380_k127_1106537_2	518766.Rmar_0949	1.17e-80	281.0	COG1763@1|root,COG1763@2|Bacteria,4PM6G@976|Bacteroidetes,1FK05@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1106537_1	573064.Mefer_0772	3.539e-82	284.0	COG0002@1|root,arCOG00495@2157|Archaea,2XTC1@28890|Euryarchaeota,23Q0I@183939|Methanococci	183939|Methanococci	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158380_k127_1108589_3	204669.Acid345_1973	2.01e-74	256.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158380_k127_1108589_5	234267.Acid_7287	4.349e-42	162.0	COG0461@1|root,COG0461@2|Bacteria,3Y6JQ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158380_k127_1108589_7	1284352.AOIG01000012_gene1543	4.616e-20	96.0	COG1051@1|root,COG1051@2|Bacteria,1TYTZ@1239|Firmicutes,4I7ZI@91061|Bacilli,26YBW@186822|Paenibacillaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158380_k127_1108589_2	204669.Acid345_2431	2.2e-82	286.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia	204432|Acidobacteriia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_1108589_8	1476583.DEIPH_ctg020orf0001	2.344e-08	64.0	COG0586@1|root,COG0586@2|Bacteria,1WKEG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158380_k127_1108589_6	331678.Cphamn1_1171	7.084e-24	107.0	COG0589@1|root,COG0589@2|Bacteria,1FDX7@1090|Chlorobi	1090|Chlorobi	T	PFAM UspA domain protein	-	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
SRR25158380_k127_1108589_4	42256.RradSPS_3047	7.858e-52	196.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158380_k127_1108589_1	234267.Acid_0489	1.599e-84	285.0	COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SRR25158380_k127_1108589_0	1128421.JAGA01000003_gene2870	5.735e-179	580.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SRR25158380_k127_1114560_3	530564.Psta_4236	2.2e-26	114.0	2EJ4R@1|root,33CVZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1114560_1	861299.J421_4047	5.439e-58	219.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
SRR25158380_k127_1114560_0	1459636.NTE_03329	2.763e-70	243.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158380_k127_1114560_2	497964.CfE428DRAFT_4652	2.249e-53	191.0	COG2320@1|root,COG2320@2|Bacteria,46TCB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR25158380_k127_1116174_2	1121087.AUCK01000004_gene1194	4.921e-34	136.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1ZGCW@1386|Bacillus	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158380_k127_1116174_0	316067.Geob_1107	3.525e-226	715.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158380_k127_1116174_1	234267.Acid_0734	1.015e-44	165.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_1120331_1	204669.Acid345_0509	3.611e-86	290.0	COG0745@1|root,COG0745@2|Bacteria,3Y4R4@57723|Acidobacteria,2JJBD@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_1120331_0	682795.AciX8_3966	5.383e-98	333.0	COG0642@1|root,COG2205@2|Bacteria,3Y2W3@57723|Acidobacteria,2JIDP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158380_k127_1120331_2	1120949.KB903303_gene6814	3.134e-05	48.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158380_k127_1130932_0	234267.Acid_2226	4.273e-207	657.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158380_k127_1130932_3	479434.Sthe_1400	6.221e-89	301.0	COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi,27XP9@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158380_k127_1130932_5	324602.Caur_3470	8.935e-40	154.0	COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158380_k127_1130932_7	1283299.AUKG01000002_gene4360	3.042e-10	64.0	COG0500@1|root,COG0500@2|Bacteria,2HQ25@201174|Actinobacteria,4CRII@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_1130932_6	1173028.ANKO01000116_gene5761	6.116e-28	115.0	COG0500@1|root,COG0500@2|Bacteria,1GQFM@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_1130932_4	1122951.ATUE01000005_gene1809	5.107e-76	275.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,3NJMZ@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158380_k127_1130932_2	357808.RoseRS_1529	2.756e-111	379.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_1130932_1	1267534.KB906754_gene3507	2.844e-151	498.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158380_k127_1139626_0	1220534.B655_0693	2.142e-40	170.0	arCOG03999@1|root,arCOG03999@2157|Archaea,2Y4KU@28890|Euryarchaeota	28890|Euryarchaeota	E	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158380_k127_1139626_1	443144.GM21_2153	3.034e-25	111.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158380_k127_1143528_1	641143.HMPREF9331_00234	2.777e-09	67.0	COG3209@1|root,COG3209@2|Bacteria,4PECV@976|Bacteroidetes,1IEW5@117743|Flavobacteriia,1ERDX@1016|Capnocytophaga	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1143528_0	452637.Oter_1367	1.062e-86	292.0	COG0262@1|root,COG0262@2|Bacteria,46XD6@74201|Verrucomicrobia,3K9XY@414999|Opitutae	414999|Opitutae	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158380_k127_1143528_2	224911.27353611	2.703e-07	55.0	2ADQ8@1|root,313FJ@2|Bacteria,1N6J6@1224|Proteobacteria,2UE6U@28211|Alphaproteobacteria,3K0DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1143543_0	1340493.JNIF01000003_gene3519	4.769e-228	738.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1143543_1	1340493.JNIF01000003_gene1935	5.122e-127	421.0	COG0498@1|root,COG0498@2|Bacteria,3Y3G4@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_1143543_2	1077974.GOEFS_017_00290	5.323e-06	51.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4GBEA@85026|Gordoniaceae	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_114686_6	215803.DB30_8025	1.071e-16	81.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SRR25158380_k127_114686_0	1267534.KB906754_gene3139	1.173e-134	433.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria,2JHSN@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158380_k127_114686_3	522772.Dacet_2456	6.614e-53	190.0	COG0105@1|root,COG0105@2|Bacteria,2GFI2@200930|Deferribacteres	200930|Deferribacteres	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158380_k127_114686_7	208439.AJAP_34275	0.0001952	50.0	2EGCD@1|root,33A46@2|Bacteria,2HKUT@201174|Actinobacteria,4E7GB@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158380_k127_114686_8	1218084.BBJK01000002_gene174	0.0004131	51.0	2BGXF@1|root,32AXE@2|Bacteria,1PXHQ@1224|Proteobacteria,2WCXJ@28216|Betaproteobacteria,1K8P8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_114686_5	1340493.JNIF01000003_gene1773	4.201e-48	178.0	COG1143@1|root,COG1143@2|Bacteria,3Y371@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SRR25158380_k127_114686_1	383372.Rcas_0031	3.747e-115	394.0	COG2114@1|root,COG2114@2|Bacteria,2GBUH@200795|Chloroflexi,376W9@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158380_k127_114686_2	316274.Haur_2605	6.633e-67	235.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi,375II@32061|Chloroflexia	32061|Chloroflexia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_114686_4	497964.CfE428DRAFT_2318	1.985e-52	194.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,46T5T@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
SRR25158380_k127_1149240_0	935567.JAES01000012_gene933	2.373e-86	298.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,1RNQB@1236|Gammaproteobacteria,1X4AJ@135614|Xanthomonadales	135614|Xanthomonadales	K	AlkA N-terminal domain	Ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158380_k127_1149240_3	1411123.JQNH01000001_gene1550	4.484e-30	129.0	2DZ1Z@1|root,34C5P@2|Bacteria,1P6W6@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_1149240_4	1535287.JP74_08005	1.001e-26	114.0	2E5IZ@1|root,330AA@2|Bacteria,1N9JX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1149240_2	450851.PHZ_c0831	2.311e-48	182.0	COG4977@1|root,COG4977@2|Bacteria,1PFG6@1224|Proteobacteria,2V7GC@28211|Alphaproteobacteria,2KJ6G@204458|Caulobacterales	204458|Caulobacterales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158380_k127_1149240_5	1547437.LL06_19070	6.984e-08	64.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,43MJP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
SRR25158380_k127_1149240_1	243090.RB12562	7.952e-59	220.0	COG1520@1|root,COG1520@2|Bacteria,2J2RN@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158380_k127_1150304_2	997346.HMPREF9374_1651	5.785e-41	172.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,27CSD@186824|Thermoactinomycetaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158380_k127_1150304_0	266264.Rmet_3321	1.575e-134	444.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VMBW@28216|Betaproteobacteria,1K3UB@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Carboxymethylenebutenolidase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH,SnoaL_2
SRR25158380_k127_1150304_1	264732.Moth_0156	3.151e-83	295.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
SRR25158380_k127_1150304_3	1288079.AUKN01000003_gene3496	9.839e-06	48.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_1151520_1	221288.JH992901_gene5747	9.681e-107	361.0	28KMN@1|root,2ZA61@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,TIR_2
SRR25158380_k127_1151520_0	221288.JH992901_gene5748	8.652e-175	584.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158380_k127_1151520_2	871963.Desdi_2020	7.586e-12	79.0	COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,24965@186801|Clostridia,261US@186807|Peptococcaceae	186801|Clostridia	M	peptidoglycan-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60,PG_binding_1
SRR25158380_k127_115347_1	234267.Acid_3242	2.967e-128	429.0	COG0577@1|root,COG0577@2|Bacteria,3Y6E4@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_115347_0	234267.Acid_3991	3.272e-174	569.0	COG0577@1|root,COG0577@2|Bacteria,3Y44G@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1171508_1	234267.Acid_7510	2.926e-178	600.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_1171508_3	401053.AciPR4_1691	2.896e-95	318.0	COG1028@1|root,COG1028@2|Bacteria,3Y2RU@57723|Acidobacteria,2JIQS@204432|Acidobacteriia	204432|Acidobacteriia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_1171508_4	1089547.KB913013_gene4158	2.848e-17	87.0	COG1917@1|root,COG1917@2|Bacteria,4NSEB@976|Bacteroidetes,47RAC@768503|Cytophagia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_1171508_2	234267.Acid_2736	1.678e-108	358.0	COG3718@1|root,COG3718@2|Bacteria	2|Bacteria	G	enzyme involved in inositol metabolism	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158380_k127_1171508_5	382464.ABSI01000023_gene595	0.0006316	53.0	COG4289@1|root,COG4289@2|Bacteria,46UB4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1171508_0	1267535.KB906767_gene1293	0.0	1043.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	oar1	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_1177714_7	929562.Emtol_3815	2.655e-18	86.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,47N7M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158380_k127_1177714_8	1144342.PMI40_00445	9.367e-13	76.0	2EKGK@1|root,33E6M@2|Bacteria,1NXZV@1224|Proteobacteria,2W38T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_1177714_1	251229.Chro_5449	9.574e-69	239.0	COG0454@1|root,COG0454@2|Bacteria,1GR2B@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158380_k127_1177714_9	1385520.N802_06960	3.136e-08	61.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4FH30@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158380_k127_1177714_0	1220582.RRU01S_30_00640	4.307e-146	478.0	COG1055@1|root,COG1055@2|Bacteria,1MVJW@1224|Proteobacteria,2U0HP@28211|Alphaproteobacteria,4BC26@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Dicarboxylate carrier protein MatC N-terminus	matC	-	-	-	-	-	-	-	-	-	-	-	CitMHS,MatC_N
SRR25158380_k127_1177714_5	1122611.KB903960_gene4317	1.048e-31	128.0	2BRP5@1|root,32KNS@2|Bacteria,2GRXV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1177714_6	880073.Calab_2951	4.923e-30	127.0	COG2020@1|root,COG2020@2|Bacteria,2NQ76@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	ICMT,PEMT
SRR25158380_k127_1177714_3	1210884.HG799470_gene14338	9.854e-50	181.0	COG3865@1|root,COG3865@2|Bacteria,2IZYS@203682|Planctomycetes	203682|Planctomycetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158380_k127_1177714_4	1122221.JHVI01000004_gene154	3.106e-47	174.0	COG0454@1|root,COG0456@2|Bacteria,1WND2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158380_k127_1177714_2	204669.Acid345_2815	3.246e-57	205.0	COG1225@1|root,COG1225@2|Bacteria,3Y4W0@57723|Acidobacteria,2JJ7A@204432|Acidobacteriia	204432|Acidobacteriia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_118720_6	1340493.JNIF01000003_gene4501	2.362e-31	126.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U2@57723|Acidobacteria	57723|Acidobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158380_k127_118720_4	1121877.JQKF01000002_gene1643	1.409e-50	184.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CN4U@84992|Acidimicrobiia	84992|Acidimicrobiia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158380_k127_118720_2	404589.Anae109_2712	8.559e-94	336.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2YUW7@29|Myxococcales	28221|Deltaproteobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158380_k127_118720_0	644282.Deba_1726	2.431e-146	483.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158380_k127_118720_3	1382359.JIAL01000001_gene2793	1.627e-86	297.0	COG2133@1|root,COG2133@2|Bacteria,3Y98P@57723|Acidobacteria,2JP56@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_118720_5	1230343.CANP01000024_gene1821	8.859e-38	150.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,1JD7G@118969|Legionellales	118969|Legionellales	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158380_k127_118720_1	1192034.CAP_0896	7.363e-120	393.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2YV60@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158380_k127_1191837_0	240015.ACP_0861	6.029e-152	495.0	COG0624@1|root,COG0624@2|Bacteria,3Y7TX@57723|Acidobacteria,2JN3C@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M20/M25/M40	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
SRR25158380_k127_1191837_1	1122962.AULH01000008_gene2083	2.16e-32	140.0	COG0457@1|root,COG0457@2|Bacteria,1Q3TC@1224|Proteobacteria,2U0J3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_16
SRR25158380_k127_1204319_0	671143.DAMO_1933	0.0	1379.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158380_k127_1204319_1	671143.DAMO_1932	4.183e-57	205.0	COG0845@1|root,COG0845@2|Bacteria,2NPS3@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158380_k127_1204749_0	1047013.AQSP01000113_gene740	1.361e-263	829.0	COG1472@1|root,COG1472@2|Bacteria,2NNR4@2323|unclassified Bacteria	2|Bacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158380_k127_12079_4	1121413.JMKT01000008_gene1459	1.437e-18	89.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2M7RW@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158380_k127_12079_1	483219.LILAB_25815	1.266e-112	373.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,4304Z@68525|delta/epsilon subdivisions,2WVJ8@28221|Deltaproteobacteria,2YV3F@29|Myxococcales	28221|Deltaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	topI	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158380_k127_12079_5	588932.JHOF01000018_gene973	2.403e-14	75.0	2EPV2@1|root,33HFI@2|Bacteria,1P4JW@1224|Proteobacteria,2UYBR@28211|Alphaproteobacteria,2KJER@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_12079_3	176299.Atu8206	5.832e-26	108.0	COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,2UC0X@28211|Alphaproteobacteria,4BFEB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Plasmid stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_12079_0	105559.Nwat_2650	2.204e-132	429.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMC9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_12079_2	525897.Dbac_1184	1.099e-74	259.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158380_k127_1208654_3	1278073.MYSTI_01766	1.903e-122	408.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1208654_0	251221.35211765	4.06e-206	668.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1208654_1	251221.35211765	9.24e-203	660.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1208654_2	234267.Acid_5466	1.016e-128	438.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1214160_3	234267.Acid_4617	4.517e-50	191.0	COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
SRR25158380_k127_1214160_5	452652.KSE_02830	4.157e-20	98.0	COG2954@1|root,COG2954@2|Bacteria,2IHDK@201174|Actinobacteria,2M36J@2063|Kitasatospora	201174|Actinobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1214160_4	658187.LDG_6943	2.156e-24	117.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria,1SGBD@1236|Gammaproteobacteria,1JCCV@118969|Legionellales	118969|Legionellales	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
SRR25158380_k127_1214160_6	525368.HMPREF0591_0970	6.769e-18	85.0	29RUC@1|root,30CY9@2|Bacteria,2GW9D@201174|Actinobacteria,23C68@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158380_k127_1214160_8	864702.OsccyDRAFT_4933	4.215e-12	73.0	COG2327@1|root,COG2327@2|Bacteria	2|Bacteria	S	slime layer polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR25158380_k127_1214160_7	1304872.JAGC01000003_gene3582	9.964e-15	81.0	COG0438@1|root,COG0438@2|Bacteria,1RH5W@1224|Proteobacteria,42UY3@68525|delta/epsilon subdivisions,2WQ9B@28221|Deltaproteobacteria,2MA2D@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1214160_0	1173027.Mic7113_4893	2.071e-128	434.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158380_k127_1214160_1	864051.BurJ1DRAFT_2047	3.263e-98	345.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VWI8@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158380_k127_1214160_2	379066.GAU_3554	1.308e-76	259.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZUC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
SRR25158380_k127_1216152_0	234267.Acid_7663	4.41e-142	456.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158380_k127_1216152_1	391625.PPSIR1_32307	2.697e-135	439.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42YD3@68525|delta/epsilon subdivisions,2WTVV@28221|Deltaproteobacteria,2YU0M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	yeiA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
SRR25158380_k127_1216152_3	251221.35210700	2.524e-91	307.0	COG0708@1|root,COG0708@2|Bacteria,1G29X@1117|Cyanobacteria	1117|Cyanobacteria	L	Exodeoxyribonuclease iii	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158380_k127_1216152_4	886293.Sinac_5558	2.746e-82	288.0	COG0624@1|root,COG0624@2|Bacteria,2IZ39@203682|Planctomycetes	203682|Planctomycetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_1216152_2	204669.Acid345_3834	5.371e-97	322.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	2|Bacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
SRR25158380_k127_1231916_3	1047013.AQSP01000089_gene1181	6.214e-47	179.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158380_k127_1231916_1	1089544.KB912942_gene1411	7.595e-90	316.0	COG2931@1|root,COG2931@2|Bacteria,2GTWD@201174|Actinobacteria	201174|Actinobacteria	Q	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1231916_4	688269.Theth_0318	7.521e-05	51.0	COG1366@1|root,COG1366@2|Bacteria,2GDAN@200918|Thermotogae	200918|Thermotogae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158380_k127_1231916_0	420662.Mpe_A3668	1.521e-115	382.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,1KMVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158380_k127_1231916_2	1132855.KB913035_gene154	9.345e-50	181.0	29MCB@1|root,308A4@2|Bacteria,1RFTR@1224|Proteobacteria,2VVTW@28216|Betaproteobacteria,2KNSV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158380_k127_123357_1	926692.AZYG01000036_gene2511	5.831e-65	232.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WBB0@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158380_k127_123357_2	1166018.FAES_3793	6.179e-05	51.0	COG2318@1|root,COG2318@2|Bacteria,4NN7V@976|Bacteroidetes,47QXV@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SRR25158380_k127_123357_0	1070319.CAGGBEG34_190038	1.951e-94	331.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158380_k127_1248636_7	4155.Migut.E01375.1.p	2.238e-07	53.0	COG0494@1|root,2QT89@2759|Eukaryota,37JK2@33090|Viridiplantae,3G9XH@35493|Streptophyta,44CKQ@71274|asterids	35493|Streptophyta	L	Nudix hydrolase	-	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0016787,GO:0019538,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	NUDIX,Peptidase_M49
SRR25158380_k127_1248636_6	1123242.JH636434_gene4029	2.166e-36	150.0	COG3055@1|root,COG3055@2|Bacteria,2IY7R@203682|Planctomycetes	203682|Planctomycetes	E	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
SRR25158380_k127_1248636_5	204669.Acid345_1456	8.578e-49	177.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158380_k127_1248636_3	1174528.JH992898_gene1315	3.638e-49	188.0	COG2367@1|root,COG2367@2|Bacteria,1G1KE@1117|Cyanobacteria,1JIXY@1189|Stigonemataceae	1117|Cyanobacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158380_k127_1248636_1	234267.Acid_6197	1.568e-94	319.0	COG2513@1|root,COG2513@2|Bacteria,3Y400@57723|Acidobacteria	57723|Acidobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158380_k127_1248636_2	1304866.K413DRAFT_5151	2.368e-51	193.0	COG0454@1|root,COG0456@2|Bacteria,1TS4G@1239|Firmicutes,25DBT@186801|Clostridia,36U9C@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158380_k127_1248636_0	357808.RoseRS_3730	2.904e-167	543.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,374X4@32061|Chloroflexia	32061|Chloroflexia	E	PFAM gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158380_k127_1248636_4	1090318.ATTI01000001_gene1733	3.722e-49	180.0	28KGE@1|root,2ZA27@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1254494_0	1122194.AUHU01000003_gene2119	3.58e-205	656.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,465NJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cecA_2	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
SRR25158380_k127_1254494_1	1146883.BLASA_1735	1.425e-96	327.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158380_k127_1260876_1	1340493.JNIF01000004_gene597	1.31e-25	115.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1260876_0	1267533.KB906741_gene585	8.351e-128	437.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Z9@57723|Acidobacteria,2JKTJ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_1261719_0	1267535.KB906767_gene4366	2.425e-137	479.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WQ@57723|Acidobacteria,2JICR@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_1268991_2	468059.AUHA01000002_gene563	2.697e-06	53.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
SRR25158380_k127_1268991_0	1128421.JAGA01000002_gene660	1.636e-113	370.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158380_k127_1275236_3	443143.GM18_1585	4.477e-77	268.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
SRR25158380_k127_1275236_2	517418.Ctha_0361	1.125e-131	443.0	COG0367@1|root,COG0367@2|Bacteria,1FDEI@1090|Chlorobi	1090|Chlorobi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158380_k127_1275236_1	1382359.JIAL01000001_gene754	2.433e-155	498.0	COG0686@1|root,COG0686@2|Bacteria,3Y3Y9@57723|Acidobacteria,2JI1M@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158380_k127_1275236_0	1379698.RBG1_1C00001G0471	2.608e-219	691.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158380_k127_1275236_4	1550091.JROE01000010_gene3131	2.071e-07	58.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_1295751_2	1307761.L21SP2_0032	1.415e-59	213.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2J65C@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158380_k127_1295751_5	240015.ACP_0941	4.146e-06	59.0	2EM83@1|root,33EX7@2|Bacteria,3Y32M@57723|Acidobacteria,2JHQ1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1295751_0	640511.BC1002_2949	2.762e-108	357.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,1K0VT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
SRR25158380_k127_1295751_4	1307761.L21SP2_1378	4.402e-14	78.0	COG1664@1|root,COG1664@2|Bacteria,2J85N@203691|Spirochaetes	203691|Spirochaetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158380_k127_1295751_3	573370.DMR_27510	1.243e-16	89.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158380_k127_1297775_0	926562.Oweho_0729	0.0	1220.0	2EX72@1|root,33QHY@2|Bacteria,4P0XX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1309471_3	1265505.ATUG01000003_gene88	1.847e-15	85.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2MJ11@213118|Desulfobacterales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158380_k127_1309471_1	1382359.JIAL01000001_gene3007	2.102e-30	134.0	COG0265@1|root,COG0265@2|Bacteria,3Y4AJ@57723|Acidobacteria,2JJ4W@204432|Acidobacteriia	204432|Acidobacteriia	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
SRR25158380_k127_1309471_0	1121430.JMLG01000017_gene309	3.369e-53	199.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,24BDQ@186801|Clostridia,261Z4@186807|Peptococcaceae	186801|Clostridia	S	Zn-dependent hydrolase, glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_1309471_2	1121413.JMKT01000001_gene1686	6.134e-21	96.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_1313862_1	195250.CM001776_gene1963	1.072e-40	156.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1GZQH@1129|Synechococcus	1117|Cyanobacteria	M	Peptidyl-prolyl cis-trans	ytfC	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158380_k127_1313862_0	401526.TcarDRAFT_2158	1.026e-120	399.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes	1239|Firmicutes	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_1313862_3	1499967.BAYZ01000044_gene2999	4.773e-07	57.0	2EPAA@1|root,33GX1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1313862_2	1403819.BATR01000010_gene390	1.001e-31	132.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia,2IVZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_1313862_4	118163.Ple7327_3680	1.612e-05	55.0	COG3678@1|root,COG3678@2|Bacteria,1G95S@1117|Cyanobacteria	1117|Cyanobacteria	NPTU	P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SRR25158380_k127_131703_1	743974.MBO_08836	1.551e-20	92.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,3NPAT@468|Moraxellaceae	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_131703_0	1122604.JONR01000025_gene4602	2.799e-118	400.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158380_k127_1322971_0	234267.Acid_5307	0.0	1257.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria	57723|Acidobacteria	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158380_k127_1322971_1	1128421.JAGA01000001_gene2144	1.117e-61	218.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1322971_2	1267535.KB906767_gene2392	1.378e-39	151.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRR25158380_k127_1326711_0	357808.RoseRS_1529	9.854e-82	304.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_1326711_1	2074.JNYD01000008_gene1228	6.39e-47	194.0	COG0443@1|root,COG3391@1|root,COG4995@1|root,COG0443@2|Bacteria,COG3391@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,HSP70
SRR25158380_k127_1326711_2	1125863.JAFN01000001_gene844	7.922e-10	73.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
SRR25158380_k127_1326711_3	1336208.JADY01000008_gene2119	9.042e-05	53.0	COG0287@1|root,COG0287@2|Bacteria	2|Bacteria	E	prephenate dehydrogenase (NADP+) activity	tyrA	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
SRR25158380_k127_1337999_0	682795.AciX8_4501	1.334e-08	62.0	arCOG13401@1|root,33MMV@2|Bacteria,3Y5TE@57723|Acidobacteria,2JNR5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158380_k127_1337999_1	204669.Acid345_0913	3.906e-07	61.0	COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1348289_1	402612.FP0865	3.473e-11	63.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia,2NVD7@237|Flavobacterium	976|Bacteroidetes	E	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
SRR25158380_k127_1348289_0	1379270.AUXF01000004_gene3139	1.556e-255	818.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_1354510_1	861299.J421_1407	1.313e-37	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158380_k127_1354510_0	1123277.KB893172_gene921	1.617e-193	621.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47Q5S@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
SRR25158380_k127_1361785_1	1218075.BAYA01000003_gene662	1.184e-17	87.0	COG0824@1|root,COG0824@2|Bacteria,1MZPN@1224|Proteobacteria,2VTCV@28216|Betaproteobacteria,1K82U@119060|Burkholderiaceae	28216|Betaproteobacteria	S	thioesterase	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
SRR25158380_k127_1361785_0	767817.Desgi_1433	2.7e-158	515.0	COG0365@1|root,COG0365@2|Bacteria,1UMN9@1239|Firmicutes,25GME@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158380_k127_1364662_2	204669.Acid345_1573	3.6e-12	72.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1364662_0	204669.Acid345_1572	1.615e-53	198.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158380_k127_1364662_1	204669.Acid345_2733	3.443e-28	130.0	COG5617@1|root,COG5617@2|Bacteria,3Y46S@57723|Acidobacteria,2JHJW@204432|Acidobacteriia	204432|Acidobacteriia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
SRR25158380_k127_1373185_1	1047013.AQSP01000124_gene2676	6.483e-58	224.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158380_k127_1373185_2	525897.Dbac_1982	8.477e-09	64.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MEXF@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR25158380_k127_1373185_3	1125863.JAFN01000001_gene2286	0.0001036	52.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SRR25158380_k127_1373185_0	204669.Acid345_1469	1.206e-97	330.0	COG4972@1|root,COG4972@2|Bacteria,3Y804@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158380_k127_1398846_1	234267.Acid_5882	1.812e-70	246.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1398846_5	1267535.KB906767_gene1326	2.089e-51	196.0	COG0250@1|root,COG0250@2|Bacteria,3Y3I1@57723|Acidobacteria,2JHYX@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1398846_3	1292034.OR37_03476	7.6e-64	237.0	COG0666@1|root,COG0666@2|Bacteria,1P877@1224|Proteobacteria,2U9TJ@28211|Alphaproteobacteria,2KIEQ@204458|Caulobacterales	204458|Caulobacterales	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1398846_7	1089547.KB913013_gene3993	3.808e-11	77.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47K73@768503|Cytophagia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
SRR25158380_k127_1398846_6	1121920.AUAU01000009_gene1864	7.191e-38	164.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1398846_0	234267.Acid_5783	5.225e-283	880.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_1398846_2	269084.syc2102_c	2.535e-64	228.0	COG4229@1|root,COG4229@2|Bacteria,1G59P@1117|Cyanobacteria,1H3Y4@1129|Synechococcus	1117|Cyanobacteria	F	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158380_k127_1398846_4	1173264.KI913949_gene37	3.268e-56	198.0	COG1791@1|root,COG1791@2|Bacteria,1G274@1117|Cyanobacteria	1117|Cyanobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
SRR25158380_k127_1401213_0	1242864.D187_003447	1.486e-34	142.0	2F8BB@1|root,340QF@2|Bacteria,1NY4M@1224|Proteobacteria,430J1@68525|delta/epsilon subdivisions,2WW1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1404285_1	234267.Acid_7677	2.544e-58	208.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_1404285_2	471853.Bcav_3521	1.149e-34	145.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876,DUF1918,Nitroreductase,TM1586_NiRdase
SRR25158380_k127_1404285_0	471853.Bcav_3520	7.137e-91	317.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_1416830_0	570952.ATVH01000011_gene436	6.406e-121	393.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2JPIZ@204441|Rhodospirillales	204441|Rhodospirillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158380_k127_1416830_3	204669.Acid345_3996	2.736e-13	74.0	2CDNF@1|root,2ZTQP@2|Bacteria,3Y955@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1416830_2	1267535.KB906767_gene284	9.937e-76	262.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158380_k127_1416830_1	682795.AciX8_4464	2.582e-120	391.0	COG0133@1|root,COG0133@2|Bacteria,3Y45B@57723|Acidobacteria,2JIVM@204432|Acidobacteriia	204432|Acidobacteriia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_1438272_0	1174528.JH992892_gene6576	5.951e-113	370.0	COG0656@1|root,COG0656@2|Bacteria,1G4UQ@1117|Cyanobacteria	1117|Cyanobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_1438272_2	497964.CfE428DRAFT_2268	5.768e-84	297.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_1438272_1	1166018.FAES_5143	6.737e-88	306.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_1448324_0	497964.CfE428DRAFT_4783	2.16e-105	351.0	COG3214@1|root,COG3214@2|Bacteria,46UTW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158380_k127_1448324_3	1121381.JNIV01000009_gene2346	5.986e-10	61.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158380_k127_1448324_4	1094508.Tsac_1170	8.885e-07	59.0	COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,24BZZ@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
SRR25158380_k127_1448324_2	243090.RB1279	2.549e-16	83.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N,Rhodanese
SRR25158380_k127_1451980_6	204669.Acid345_0373	7.425e-16	87.0	COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria,2JIVR@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_1451980_7	1316927.ATKI01000067_gene1099	5.69e-09	67.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,1RNSP@1236|Gammaproteobacteria,1YN81@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	ybhP	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158380_k127_1451980_5	1123371.ATXH01000011_gene96	2.875e-33	138.0	COG1234@1|root,COG1234@2|Bacteria,2GGU2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158380_k127_1451980_4	1123277.KB893173_gene1820	1.626e-48	182.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158380_k127_1451980_3	323848.Nmul_A0701	1.505e-54	198.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2VQ83@28216|Betaproteobacteria,371PF@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Scaffold protein Nfu/NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SRR25158380_k127_1451980_2	401053.AciPR4_3379	9.93e-124	407.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1451980_0	234267.Acid_3898	3.152e-190	617.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158380_k127_1451980_1	234267.Acid_1490	1.146e-159	525.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158380_k127_1463190_1	7070.TC000272-PA	1.226e-77	267.0	COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria,41XDM@6656|Arthropoda,3SIYY@50557|Insecta	33208|Metazoa	Q	Oxidoreductase activity. It is involved in the biological process described with metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_1463190_0	42256.RradSPS_0832	2.435e-83	291.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4CU00@84995|Rubrobacteria	84995|Rubrobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158380_k127_1463190_2	886293.Sinac_3059	3.741e-54	199.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
SRR25158380_k127_1463190_3	521674.Plim_0007	1.664e-16	80.0	COG1146@1|root,COG1146@2|Bacteria,2J3XM@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_146462_2	204669.Acid345_3543	6.375e-115	382.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
SRR25158380_k127_146462_1	313612.L8106_12235	2.149e-219	721.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158380_k127_146462_0	1267533.KB906735_gene4931	3.26e-235	739.0	COG1032@1|root,COG1032@2|Bacteria,3Y7D8@57723|Acidobacteria,2JMKA@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158380_k127_146462_4	1122169.AREN01000005_gene1844	6.147e-44	170.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1JCNU@118969|Legionellales	1236|Gammaproteobacteria	S	Belongs to the UPF0276 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
SRR25158380_k127_1469124_1	118173.KB235914_gene469	4.217e-85	290.0	COG0566@1|root,COG0566@2|Bacteria,1G5MN@1117|Cyanobacteria	1117|Cyanobacteria	J	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158380_k127_1469124_3	1385520.N802_03300	7.298e-49	179.0	COG2020@1|root,COG2020@2|Bacteria,2IP2M@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158380_k127_1469124_0	234267.Acid_6737	4.13e-87	293.0	2CSUB@1|root,32SRY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1469124_2	857087.Metme_1552	7.795e-55	199.0	28I9E@1|root,2Z8C2@2|Bacteria,1RBP7@1224|Proteobacteria,1S2SQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
SRR25158380_k127_1469124_4	1380346.JNIH01000001_gene4363	6.98e-41	153.0	COG4122@1|root,COG4122@2|Bacteria,2GJCJ@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158380_k127_1472999_6	234267.Acid_2681	1.621e-58	209.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
SRR25158380_k127_1472999_8	929713.NIASO_06590	1.04e-12	70.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IPUA@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_1472999_9	380358.XALC_0062	0.0005623	44.0	COG3661@1|root,COG3661@2|Bacteria,1MXKA@1224|Proteobacteria,1RP0V@1236|Gammaproteobacteria,1X5RV@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycosyl hydrolase 67 family	aguA	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
SRR25158380_k127_1472999_2	661478.OP10G_4440	2.389e-181	588.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
SRR25158380_k127_1472999_0	926559.JoomaDRAFT_3019	1.82e-286	897.0	COG1472@1|root,COG1472@2|Bacteria,4NEBU@976|Bacteroidetes,1I05R@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_1472999_1	1267535.KB906767_gene3020	1.042e-215	683.0	COG0457@1|root,COG0457@2|Bacteria,3Y3WM@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_1472999_4	1267535.KB906767_gene4411	1.207e-88	305.0	COG0457@1|root,COG0457@2|Bacteria,3Y75D@57723|Acidobacteria,2JKA7@204432|Acidobacteriia	204432|Acidobacteriia	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR25158380_k127_1472999_5	234267.Acid_3491	4.344e-61	227.0	COG0457@1|root,COG0457@2|Bacteria,3Y8AI@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158380_k127_1472999_3	234267.Acid_3494	9.855e-95	323.0	COG0457@1|root,COG0457@2|Bacteria,3Y6B2@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158380_k127_1472999_7	234267.Acid_2620	1.629e-14	86.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1476573_1	309807.SRU_0691	7.034e-191	616.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1FIND@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
SRR25158380_k127_1476573_0	1121957.ATVL01000008_gene4409	3.191e-301	942.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47UBJ@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_1476573_2	401053.AciPR4_0750	2.866e-61	221.0	2DSXC@1|root,33HTB@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
SRR25158380_k127_1476573_3	1267535.KB906767_gene5168	6.072e-53	192.0	COG3616@1|root,COG3616@2|Bacteria,3Y5RJ@57723|Acidobacteria,2JNYN@204432|Acidobacteriia	204432|Acidobacteriia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158380_k127_1478433_6	1122604.JONR01000034_gene418	5.359e-13	77.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1478433_2	28072.Nos7524_4911	4.342e-73	252.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1HMWG@1161|Nostocales	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158380_k127_1478433_0	1123368.AUIS01000024_gene954	3.105e-168	539.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
SRR25158380_k127_1478433_1	118173.KB235914_gene817	2.64e-80	275.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,1HGKE@1150|Oscillatoriales	1117|Cyanobacteria	O	Ribosomal RNA adenine dimethylase	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158380_k127_1478433_3	937777.Deipe_2737	1.832e-34	136.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_1478433_4	1453505.JASY01000004_gene1899	1.547e-14	81.0	COG0346@1|root,COG0346@2|Bacteria,4NSWT@976|Bacteroidetes,1I4YP@117743|Flavobacteriia,2NX7P@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_1478433_5	153721.MYP_3352	2.213e-13	73.0	2CK13@1|root,33002@2|Bacteria,4NXF7@976|Bacteroidetes,47W5F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1489031_2	671143.DAMO_0040	6.478e-71	249.0	COG0577@1|root,COG0577@2|Bacteria,2NQJU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1489031_1	1267535.KB906767_gene3519	1.487e-82	291.0	COG0845@1|root,COG0845@2|Bacteria,3Y50Z@57723|Acidobacteria,2JMYN@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158380_k127_1489031_0	1379698.RBG1_1C00001G1666	1.379e-86	292.0	COG1136@1|root,COG1136@2|Bacteria,2NPA8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_1489327_6	291985.CCSI01000001_gene1855	1.843e-11	69.0	2C6BD@1|root,2ZZIY@2|Bacteria,1NWJY@1224|Proteobacteria,2USK5@28211|Alphaproteobacteria,2KAE8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1489327_5	448385.sce9285	1.899e-26	109.0	COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,43843@68525|delta/epsilon subdivisions,2X9WS@28221|Deltaproteobacteria,2YVMZ@29|Myxococcales	28221|Deltaproteobacteria	S	COG3668 Plasmid stabilization system protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1489327_2	1173022.Cri9333_0733	1.58e-102	338.0	COG0426@1|root,COG0426@2|Bacteria,1GC5X@1117|Cyanobacteria	1117|Cyanobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1489327_4	1267535.KB906767_gene3397	2.833e-39	150.0	COG1977@1|root,COG1977@2|Bacteria,3Y5J3@57723|Acidobacteria,2JJVU@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1489327_0	1382359.JIAL01000001_gene657	1.929e-222	694.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158380_k127_1489327_3	1254432.SCE1572_33565	2.071e-90	309.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158380_k127_1489327_1	378806.STAUR_6062	1.332e-106	355.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
SRR25158380_k127_1490787_1	404589.Anae109_3355	8.713e-18	85.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158380_k127_1490787_0	404589.Anae109_3354	7.66e-99	339.0	COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158380_k127_1495241_0	234267.Acid_3573	5.964e-29	130.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158380_k127_1495241_1	455436.DS989811_gene1730	9.463e-13	78.0	COG1018@1|root,COG3239@1|root,COG1018@2|Bacteria,COG3239@2|Bacteria,1NQ1W@1224|Proteobacteria,1RQTG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158380_k127_1497026_2	1463921.JODF01000036_gene1138	5.484e-147	482.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_1497026_0	1121015.N789_06360	1.273e-148	493.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria,1X44S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158380_k127_1497026_1	1382359.JIAL01000001_gene2048	1.084e-147	479.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria,2JI17@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158380_k127_1516913_1	65393.PCC7424_4786	2.203e-07	61.0	COG1357@1|root,COG3972@1|root,COG1357@2|Bacteria,COG3972@2|Bacteria,1G0CE@1117|Cyanobacteria,3KHHY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NERD,Pentapeptide,UvrD_C_2
SRR25158380_k127_1516913_2	1089552.KI911559_gene1924	7.18e-05	50.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2JT69@204441|Rhodospirillales	204441|Rhodospirillales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158380_k127_1516913_0	1340493.JNIF01000004_gene288	3.652e-40	169.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20951	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	PQQ_2
SRR25158380_k127_1517677_2	1170562.Cal6303_4565	8.159e-18	93.0	COG0457@1|root,COG0457@2|Bacteria,1G649@1117|Cyanobacteria,1HM2D@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_1517677_0	234267.Acid_0759	0.0	1084.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,Peptidase_S9
SRR25158380_k127_1517677_1	880073.Calab_0645	1.752e-120	396.0	COG3537@1|root,COG3537@2|Bacteria,2NQQ0@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
SRR25158380_k127_1520451_5	1121324.CLIT_23c00490	4.318e-10	65.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia	186801|Clostridia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158380_k127_1520451_0	443143.GM18_2435	1.458e-174	557.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283,ko:K03609	-	-	-	-	ko00000,ko02035,ko02044,ko03036,ko04812	-	-	-	CbiA,FHA,T2SSE
SRR25158380_k127_1520451_2	1267533.KB906738_gene2057	1.173e-56	215.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria,2JJ91@204432|Acidobacteriia	204432|Acidobacteriia	U	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158380_k127_1520451_3	243090.RB5942	1.192e-53	200.0	COG2064@1|root,COG2064@2|Bacteria,2IYG1@203682|Planctomycetes	203682|Planctomycetes	NU	Secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158380_k127_1520451_4	883.DvMF_2735	3.717e-17	94.0	COG0457@1|root,COG0457@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2M93P@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158380_k127_1520451_1	443143.GM18_2444	3.775e-79	274.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria,43SA6@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158380_k127_1525783_1	1123242.JH636434_gene5302	2.191e-53	201.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1525783_0	234267.Acid_5749	2.163e-176	585.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_1525783_2	1267534.KB906754_gene3444	4.36e-42	160.0	COG4319@1|root,COG4319@2|Bacteria,3Y5FP@57723|Acidobacteria,2JN7M@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_1525783_4	1239962.C943_01904	1.974e-35	140.0	COG0627@1|root,COG4188@1|root,COG0627@2|Bacteria,COG4188@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_1525783_3	1121904.ARBP01000052_gene3646	1.441e-38	154.0	COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_1539722_1	909663.KI867151_gene3015	1.079e-33	132.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2MQ5Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158380_k127_1539722_2	1273125.Rrhod_0024	1.162e-20	96.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4FW9V@85025|Nocardiaceae	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158380_k127_1539722_0	370438.PTH_0517	4.806e-152	494.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,260K5@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158380_k127_1539722_4	330214.NIDE3794	6.473e-08	55.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR25158380_k127_1539722_3	1297742.A176_01743	8.811e-16	79.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158380_k127_1549635_1	234267.Acid_1953	2.525e-212	672.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1549635_2	105559.Nwat_2961	8.03e-07	51.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,1S8NU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158380_k127_1549635_0	215803.DB30_0576	0.0	1052.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158380_k127_1550540_3	1379270.AUXF01000001_gene2693	7.267e-29	119.0	2AEVR@1|root,314TB@2|Bacteria,1ZUJ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158380_k127_1550540_4	472759.Nhal_1660	4.721e-25	111.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1SA5G@1236|Gammaproteobacteria,1X2JB@135613|Chromatiales	1236|Gammaproteobacteria	K	PFAM Transcription regulator MerR DNA binding	zntR	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K08365,ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158380_k127_1550540_0	1125863.JAFN01000001_gene1462	0.0	1134.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158380_k127_1550540_5	401053.AciPR4_1335	3.924e-17	87.0	2AAGQ@1|root,30ZTQ@2|Bacteria,3Y4IN@57723|Acidobacteria,2JJDR@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
SRR25158380_k127_1550540_1	443144.GM21_0397	1.994e-79	277.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome C family protein	mtrA	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
SRR25158380_k127_1550540_2	443144.GM21_0398	8.303e-34	145.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Ail_Lom,MtrB_PioB
SRR25158380_k127_1555273_1	497964.CfE428DRAFT_3619	2.909e-62	238.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,46VB0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
SRR25158380_k127_1555273_2	1131269.AQVV01000025_gene2327	4.812e-45	179.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HTH_31
SRR25158380_k127_1555273_4	234267.Acid_5978	5.444e-13	78.0	2EU62@1|root,33MNN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
SRR25158380_k127_1555273_5	326427.Cagg_1633	1.099e-11	78.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158380_k127_1555273_6	383372.Rcas_2061	1.25e-09	70.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158380_k127_1555273_3	1089550.ATTH01000001_gene2051	2.011e-13	83.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1FIWV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158380_k127_1555273_7	309801.trd_0615	2.069e-08	66.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,27Y7S@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158380_k127_1555273_0	1267535.KB906767_gene921	1.012e-84	293.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZF@57723|Acidobacteria,2JKHI@204432|Acidobacteriia	204432|Acidobacteriia	S	type VI secretion protein, VC_A0114 family	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
SRR25158380_k127_1556458_2	1267535.KB906767_gene5069	5.51e-126	409.0	28HGI@1|root,2Z7SC@2|Bacteria,3Y3VE@57723|Acidobacteria,2JICD@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1556458_3	357808.RoseRS_4472	1.487e-108	365.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158380_k127_1556458_5	1268072.PSAB_02815	1.389e-43	162.0	COG1310@1|root,COG1310@2|Bacteria,1VKT4@1239|Firmicutes	1239|Firmicutes	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158380_k127_1556458_0	44251.PDUR_03270	1.793e-198	629.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,271Z6@186822|Paenibacillaceae	91061|Bacilli	H	ThiS family	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRR25158380_k127_1556458_1	1379270.AUXF01000001_gene2011	2.424e-181	590.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,Peptidase_M42
SRR25158380_k127_1556458_6	335543.Sfum_0084	4.412e-35	138.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158380_k127_1556458_4	525904.Tter_2869	5.188e-93	308.0	COG3211@1|root,COG3211@2|Bacteria	2|Bacteria	O	Phosphatase	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158380_k127_1563419_0	243231.GSU0337	6.94e-169	541.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,43SY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_1563419_1	330214.NIDE0778	5.67e-39	164.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158380_k127_1572701_1	1166018.FAES_3836	2.796e-87	293.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158380_k127_1572701_0	1183438.GKIL_4354	3.273e-202	661.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1572701_2	278963.ATWD01000001_gene3285	1.25e-30	124.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_1575438_0	234267.Acid_5152	7.76e-135	455.0	COG4932@1|root,COG4932@2|Bacteria,3Y9AV@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1575438_1	717605.Theco_1624	5.899e-59	215.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,26RVP@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158380_k127_1581667_0	227882.SAV_849	3.099e-126	419.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	B12-binding,Radical_SAM
SRR25158380_k127_1581667_2	880073.Calab_2563	3.432e-43	164.0	COG1020@1|root,COG1020@2|Bacteria,2NQG0@2323|unclassified Bacteria	2|Bacteria	Q	COGs COG1020 Non-ribosomal peptide synthetase modules and related protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Sulfotransfer_3
SRR25158380_k127_1581667_1	63737.Npun_F2181	9.547e-122	400.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR25158380_k127_1582922_0	1379698.RBG1_1C00001G0607	1.01e-118	396.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158380_k127_1582922_3	1206735.BAGG01000054_gene2207	1.068e-09	65.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria,4G4QR@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158380_k127_1582922_1	1123508.JH636445_gene6656	5.349e-47	173.0	COG1917@1|root,COG1917@2|Bacteria,2J31X@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
SRR25158380_k127_1582922_2	1122612.AUBA01000002_gene1786	6.864e-10	68.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1R7EM@1224|Proteobacteria,2TRZT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ
SRR25158380_k127_1588035_7	408672.NBCG_00967	6.06e-05	52.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4DPBR@85009|Propionibacteriales	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158380_k127_1588035_1	1267535.KB906767_gene3318	5.042e-133	434.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158380_k127_1588035_3	331869.BAL199_16858	4.029e-72	247.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158380_k127_1588035_6	1123267.JONN01000001_gene728	1.776e-24	115.0	COG4219@1|root,COG4219@2|Bacteria,1P0K4@1224|Proteobacteria,2UVBF@28211|Alphaproteobacteria,2K7R8@204457|Sphingomonadales	204457|Sphingomonadales	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1588035_5	1449976.KALB_4375	1.584e-35	145.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4E7BJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_1588035_2	234267.Acid_1969	1.53e-109	368.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria	2|Bacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_1588035_4	1123508.JH636440_gene2901	2.244e-59	207.0	COG0346@1|root,COG0346@2|Bacteria,2J081@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_1588035_0	234267.Acid_7338	8.189e-156	502.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_1593070_0	1340493.JNIF01000003_gene4436	3.949e-101	353.0	COG4206@1|root,COG4206@2|Bacteria,3Y42S@57723|Acidobacteria	57723|Acidobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_1593070_1	1340493.JNIF01000003_gene2209	9.291e-74	254.0	COG0064@1|root,COG0064@2|Bacteria,3Y2TJ@57723|Acidobacteria	57723|Acidobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158380_k127_1615743_0	1123008.KB905700_gene2139	8.847e-104	341.0	COG1680@1|root,COG1680@2|Bacteria,4PHZD@976|Bacteroidetes,2G1GG@200643|Bacteroidia,2312Z@171551|Porphyromonadaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_1615743_3	398767.Glov_3411	2.215e-36	142.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,43SIE@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158380_k127_1615743_1	234267.Acid_7935	1.884e-103	344.0	COG0825@1|root,COG0825@2|Bacteria,3Y34D@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158380_k127_1615743_2	1499967.BAYZ01000009_gene5298	3.981e-86	301.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
SRR25158380_k127_1619610_2	179408.Osc7112_6220	1.07e-43	169.0	COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
SRR25158380_k127_1619610_1	234267.Acid_1178	3.924e-87	295.0	COG1692@1|root,COG1692@2|Bacteria,3Y3YJ@57723|Acidobacteria	57723|Acidobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158380_k127_1619610_3	1382359.JIAL01000001_gene1197	8.637e-16	82.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRR25158380_k127_1619610_0	338966.Ppro_2303	1.523e-143	479.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158380_k127_1627766_4	196367.JNFG01000026_gene8203	5.626e-43	160.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,1K17P@119060|Burkholderiaceae	28216|Betaproteobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158380_k127_1627766_5	1500257.JQNM01000001_gene3801	8.776e-42	162.0	29NNR@1|root,31FC3@2|Bacteria,1R39F@1224|Proteobacteria,2TZZK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1627766_1	1123508.JH636444_gene5358	1.818e-197	627.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158380_k127_1627766_6	177437.HRM2_33460	3.957e-40	162.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2MJDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_1627766_2	1297742.A176_06066	1.594e-181	572.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,42RN7@68525|delta/epsilon subdivisions,2WNNX@28221|Deltaproteobacteria,2Z317@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.14,1.2.1.46	ko:K00008,ko:K00148,ko:K18369	ko00040,ko00051,ko00625,ko00640,ko00680,ko01100,ko01120,ko01200,map00040,map00051,map00625,map00640,map00680,map01100,map01120,map01200	M00014	R00604,R00875,R01896,R10703	RC00085,RC00102,RC00188,RC00545	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_1627766_8	521045.Kole_1207	4.025e-10	65.0	2FCRF@1|root,344UM@2|Bacteria,2GE8C@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1627766_7	278963.ATWD01000001_gene1666	7.273e-16	83.0	2AAGQ@1|root,30ZTQ@2|Bacteria,3Y4IN@57723|Acidobacteria,2JJDR@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
SRR25158380_k127_1627766_0	497964.CfE428DRAFT_1132	2.503e-231	724.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SRR25158380_k127_1627766_3	1278073.MYSTI_05802	7.372e-61	212.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
SRR25158380_k127_1640941_3	685035.ADAE01000011_gene1261	2.617e-05	55.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
SRR25158380_k127_1640941_0	204669.Acid345_4697	9.122e-251	783.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158380_k127_1640941_2	1033810.HLPCO_001745	5.009e-17	87.0	COG3557@1|root,COG3557@2|Bacteria	2|Bacteria	J	Belongs to the UPF0374 family	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
SRR25158380_k127_1640941_1	647113.Metok_0228	1.165e-85	289.0	COG0176@1|root,arCOG05061@2157|Archaea,2XTET@28890|Euryarchaeota,23Q23@183939|Methanococci	183939|Methanococci	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158380_k127_1644937_6	278963.ATWD01000002_gene684	2.213e-29	124.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_1644937_5	886293.Sinac_1778	1.236e-30	132.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
SRR25158380_k127_1644937_7	1047013.AQSP01000139_gene2383	6.684e-15	88.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516,ko:K05801	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DUF4388,DnaJ,DnaJ_C,TerB,WD40
SRR25158380_k127_1644937_4	429009.Adeg_1201	1.009e-37	150.0	COG2203@1|root,COG2206@1|root,COG4936@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG4936@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42GDE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HD,PAS_9,PocR
SRR25158380_k127_1644937_9	1121406.JAEX01000031_gene2563	7.445e-09	66.0	COG3064@1|root,COG3392@1|root,COG3064@2|Bacteria,COG3392@2|Bacteria,1R84X@1224|Proteobacteria,42NGF@68525|delta/epsilon subdivisions,2WKYS@28221|Deltaproteobacteria,2MA2K@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM D12 class N6 adenine-specific DNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MethyltransfD12
SRR25158380_k127_1644937_2	234267.Acid_2403	2.035e-89	302.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria	57723|Acidobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_1644937_1	1267535.KB906767_gene897	1.226e-94	318.0	COG5002@1|root,COG5002@2|Bacteria,3Y99C@57723|Acidobacteria,2JP5N@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_1644937_0	1267533.KB906738_gene2031	2.539e-109	360.0	COG1398@1|root,COG1398@2|Bacteria,3Y3F9@57723|Acidobacteria,2JHWH@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158380_k127_1644937_3	518766.Rmar_0303	1.009e-51	201.0	COG0477@1|root,COG2814@2|Bacteria,4PF2D@976|Bacteroidetes,1FK1C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1644937_8	412597.AEPN01000006_gene1611	2.459e-10	62.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,2PWI0@265|Paracoccus	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_1646145_0	717605.Theco_0557	1.318e-258	824.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,4HBKW@91061|Bacilli,26S7W@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	bmnA	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_1646145_1	1267534.KB906755_gene4156	2.849e-135	437.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Z2@57723|Acidobacteria,2JMN3@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158380_k127_164983_1	945713.IALB_2785	4.866e-28	115.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SRR25158380_k127_164983_0	1382306.JNIM01000001_gene3513	8.578e-153	494.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_164983_2	278963.ATWD01000001_gene3145	3.614e-08	64.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158380_k127_1653565_0	693661.Arcve_1917	1.844e-35	143.0	COG1059@1|root,arCOG04357@2157|Archaea,2XWSZ@28890|Euryarchaeota,24660@183980|Archaeoglobi	183980|Archaeoglobi	L	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)	ogg	-	4.2.99.18	ko:K03653	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_1653565_2	1183438.GKIL_4114	9.727e-10	71.0	COG3577@1|root,COG3577@2|Bacteria,1G044@1117|Cyanobacteria	1117|Cyanobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
SRR25158380_k127_1653565_1	388467.A19Y_2179	3.54e-24	109.0	COG1848@1|root,COG1848@2|Bacteria,1G51H@1117|Cyanobacteria,1HAWH@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158380_k127_1655317_0	313624.NSP_46940	3.074e-121	404.0	COG0671@1|root,COG0671@2|Bacteria,1G24P@1117|Cyanobacteria,1HK6H@1161|Nostocales	1117|Cyanobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1655317_1	1144275.COCOR_07409	6.214e-110	372.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,438C4@68525|delta/epsilon subdivisions,2WYM4@28221|Deltaproteobacteria,2YWIJ@29|Myxococcales	28221|Deltaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158380_k127_1655317_3	502025.Hoch_0087	1.6e-66	247.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_1655317_2	1379698.RBG1_1C00001G1167	1.415e-70	243.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_1655845_2	714943.Mucpa_3516	7.903e-09	65.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,1IT0C@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158380_k127_1655845_3	1453505.JASY01000001_gene3271	1.573e-07	61.0	COG0745@1|root,COG0745@2|Bacteria,4NSD3@976|Bacteroidetes,1I48M@117743|Flavobacteriia,2NYV8@237|Flavobacterium	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158380_k127_1655845_0	1267533.KB906739_gene2615	3.34e-64	231.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158380_k127_1655845_1	472759.Nhal_2071	8.846e-43	167.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR25158380_k127_1661400_0	929556.Solca_1617	4.428e-315	984.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1IP3T@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	bga	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_1661400_1	715226.ABI_19720	5.058e-43	162.0	COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,2TWSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SRR25158380_k127_1663054_2	316067.Geob_2612	6.121e-81	276.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158380_k127_1663054_1	443143.GM18_3078	8.057e-112	369.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158380_k127_1663054_3	204669.Acid345_4505	9.796e-27	111.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria,2JJPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158380_k127_1663054_0	234267.Acid_1167	9.517e-171	545.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158380_k127_1663054_4	204669.Acid345_3697	3.403e-11	64.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria,2JK7K@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158380_k127_1678696_3	204669.Acid345_0509	3.73e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,3Y4R4@57723|Acidobacteria,2JJBD@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_1678696_2	682795.AciX8_3966	8.828e-92	315.0	COG0642@1|root,COG2205@2|Bacteria,3Y2W3@57723|Acidobacteria,2JIDP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158380_k127_1678696_0	861299.J421_1936	2.122e-199	631.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158380_k127_1680718_1	502025.Hoch_3248	1.812e-189	612.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158380_k127_1680718_2	404589.Anae109_1211	2.833e-90	309.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
SRR25158380_k127_1680718_0	215803.DB30_7050	1.675e-195	627.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria,439AJ@68525|delta/epsilon subdivisions,2X4I4@28221|Deltaproteobacteria,2YZ2B@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1680718_4	1265310.CCBD010000050_gene1947	9.94e-12	76.0	COG0500@1|root,COG2226@2|Bacteria,2IDZY@201174|Actinobacteria,237BP@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW,Methyltransf_11
SRR25158380_k127_1680718_3	234267.Acid_4282	8.29e-38	146.0	COG5485@1|root,COG5485@2|Bacteria,3Y8NT@57723|Acidobacteria	57723|Acidobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158380_k127_1680718_5	1121920.AUAU01000020_gene2543	1.166e-07	54.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000020_gene2543|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1718551_1	1267533.KB906738_gene2330	4.785e-103	347.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158380_k127_1718551_2	234267.Acid_4268	1.917e-07	56.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1718551_0	234267.Acid_1154	1.287e-156	531.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_1721570_1	1128421.JAGA01000002_gene1512	1.312e-115	381.0	COG0153@1|root,COG0153@2|Bacteria,2NQRK@2323|unclassified Bacteria	2|Bacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158380_k127_1721570_2	717605.Theco_0957	1.526e-111	370.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,26SH5@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158380_k127_1721570_0	661478.OP10G_1297	2.213e-119	391.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158380_k127_1742397_1	1117108.PAALTS15_21843	1.051e-07	59.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,26ZTC@186822|Paenibacillaceae	91061|Bacilli	S	general stress protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR25158380_k127_1742397_0	1267535.KB906767_gene2620	0.0	1042.0	COG0060@1|root,COG0060@2|Bacteria,3Y3JW@57723|Acidobacteria,2JIQ2@204432|Acidobacteriia	204432|Acidobacteriia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158380_k127_1771755_2	330214.NIDE4314	9.135e-71	247.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1771755_0	234267.Acid_7263	0.0	1232.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158380_k127_1771755_1	234267.Acid_7005	1.437e-112	396.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_1775263_1	671143.DAMO_2498	2.952e-117	384.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_1775263_2	1268239.PALB_29710	1.822e-58	210.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,2Q13K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158380_k127_1775263_4	1121930.AQXG01000001_gene1317	7.215e-20	98.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158380_k127_1775263_3	1121104.AQXH01000001_gene1649	5.708e-41	159.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158380_k127_1775263_0	316274.Haur_2944	2.994e-171	544.0	COG1830@1|root,COG1830@2|Bacteria,2G8VI@200795|Chloroflexi	200795|Chloroflexi	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158380_k127_1784591_0	251221.35212369	6.185e-127	422.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	MA20_39390	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158380_k127_1784591_2	649349.Lbys_1863	1.17e-90	313.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158380_k127_1784591_1	246197.MXAN_0850	2.301e-104	346.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158380_k127_1791886_1	926550.CLDAP_34990	1.023e-89	303.0	COG3507@1|root,COG3507@2|Bacteria,2G9A8@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SRR25158380_k127_1791886_0	1267535.KB906767_gene2807	8.807e-108	383.0	COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_1797865_2	338966.Ppro_0084	0.0003469	52.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43T8P@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
SRR25158380_k127_1797865_1	861299.J421_1115	3.016e-82	284.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1797865_0	266117.Rxyl_1069	3.028e-174	561.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CSAD@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158380_k127_1808284_3	234267.Acid_0267	3.51e-65	231.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hydro_43
SRR25158380_k127_1808284_0	1340493.JNIF01000003_gene4144	8.755e-243	783.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_1808284_4	1340493.JNIF01000003_gene4144	8.847e-39	156.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_1808284_2	1396418.BATQ01000175_gene2823	8.898e-82	287.0	COG3828@1|root,COG3828@2|Bacteria,46VX0@74201|Verrucomicrobia,2IUD7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
SRR25158380_k127_1808284_1	926549.KI421517_gene2782	6.912e-163	524.0	COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes,47JIW@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_1818315_0	83406.HDN1F_22600	9.759e-53	201.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158380_k127_1818315_1	234267.Acid_5633	1.27e-37	150.0	COG1238@1|root,COG1238@2|Bacteria,3Y5BJ@57723|Acidobacteria	57723|Acidobacteria	I	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_1822644_4	1303518.CCALI_00191	2.143e-06	59.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gspG_1	-	-	ko:K02246,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10,T2SSG
SRR25158380_k127_1822644_2	555079.Toce_0654	4.157e-84	291.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,42FJX@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158380_k127_1822644_3	903818.KI912268_gene1547	5.708e-25	109.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria	57723|Acidobacteria	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
SRR25158380_k127_1822644_0	1047013.AQSP01000140_gene2471	7.913e-125	413.0	COG0206@1|root,COG0206@2|Bacteria,2NNSU@2323|unclassified Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158380_k127_1822644_1	316067.Geob_0785	1.388e-117	391.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158380_k127_1834488_6	631362.Thi970DRAFT_00444	2.985e-38	154.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WZ62@135613|Chromatiales	135613|Chromatiales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
SRR25158380_k127_1834488_10	1265505.ATUG01000002_gene2187	0.0004736	48.0	COG1462@1|root,COG3409@1|root,COG1462@2|Bacteria,COG3409@2|Bacteria,1R7FJ@1224|Proteobacteria,42RKP@68525|delta/epsilon subdivisions,2WNHR@28221|Deltaproteobacteria,2MMC5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1834488_1	639282.DEFDS_1463	1.611e-254	813.0	COG0013@1|root,COG0013@2|Bacteria,2GF1K@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158380_k127_1834488_8	234267.Acid_0965	1.204e-10	69.0	COG2137@1|root,COG2137@2|Bacteria,3Y4WT@57723|Acidobacteria	57723|Acidobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158380_k127_1834488_4	398767.Glov_1672	1.988e-60	221.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158380_k127_1834488_0	1382306.JNIM01000001_gene2853	6.165e-302	938.0	COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi	200795|Chloroflexi	T	PrkA AAA domain protein	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
SRR25158380_k127_1834488_7	439235.Dalk_1975	7.64e-38	155.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria,2MPGU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158380_k127_1834488_3	1382306.JNIM01000001_gene2852	9.304e-154	495.0	COG2718@1|root,COG2718@2|Bacteria,2G6DB@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
SRR25158380_k127_1834488_2	1382306.JNIM01000001_gene2851	4.177e-179	572.0	COG2719@1|root,COG2719@2|Bacteria,2G5PX@200795|Chloroflexi	200795|Chloroflexi	S	SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
SRR25158380_k127_1834488_5	926550.CLDAP_09140	4.243e-58	207.0	COG3832@1|root,COG3832@2|Bacteria,2G9I3@200795|Chloroflexi	200795|Chloroflexi	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158380_k127_1834488_9	215803.DB30_1685	1.872e-06	49.0	28M67@1|root,31CRD@2|Bacteria,1QASJ@1224|Proteobacteria,438U9@68525|delta/epsilon subdivisions,2X40D@28221|Deltaproteobacteria,2YXSR@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1835289_1	234267.Acid_6424	9.05e-78	288.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3Y3VQ@57723|Acidobacteria	57723|Acidobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158380_k127_1835289_0	326427.Cagg_1370	8.378e-85	288.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,376NT@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158380_k127_1836341_1	861299.J421_5995	5.239e-83	295.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	AAA_16,Abhydrolase_1,PD40,Trans_reg_C
SRR25158380_k127_1836341_3	1380355.JNIJ01000008_gene1888	1.921e-51	208.0	COG0596@1|root,COG0596@2|Bacteria,1N54X@1224|Proteobacteria,2U1C2@28211|Alphaproteobacteria,3JVMZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_1836341_5	864069.MicloDRAFT_00031190	2.676e-39	169.0	COG0596@1|root,COG0596@2|Bacteria,1R9VJ@1224|Proteobacteria,2U26I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_1836341_4	1254432.SCE1572_24325	4.517e-51	207.0	COG0596@1|root,COG0596@2|Bacteria,1RKIV@1224|Proteobacteria	1224|Proteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_1836341_2	1123267.JONN01000001_gene1706	1.135e-77	273.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,2UKB8@28211|Alphaproteobacteria,2K99E@204457|Sphingomonadales	204457|Sphingomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158380_k127_1836341_6	378806.STAUR_5272	3.351e-09	58.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,430DJ@68525|delta/epsilon subdivisions,2WVKM@28221|Deltaproteobacteria,2YWIB@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
SRR25158380_k127_1836341_0	1121428.DESHY_160144___1	7.464e-148	475.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,260IH@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158380_k127_1849474_2	204669.Acid345_1393	6.316e-112	390.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	204432|Acidobacteriia	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
SRR25158380_k127_1849474_1	1340493.JNIF01000003_gene2599	5.733e-163	524.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_1849474_5	1122921.KB898201_gene3195	6.465e-37	154.0	COG0535@1|root,COG0535@2|Bacteria,1UXWS@1239|Firmicutes	1239|Firmicutes	C	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158380_k127_1849474_6	357808.RoseRS_2020	5.021e-33	142.0	COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi,3765P@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,MGDG_synth
SRR25158380_k127_1849474_4	215803.DB30_4430	2.616e-54	201.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YV5Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.304,1.1.1.47,1.1.1.76	ko:K00034,ko:K03366	ko00030,ko00650,ko01120,ko01200,map00030,map00650,map01120,map01200	-	R01520,R01521,R02855,R02946,R03707,R09078,R10505	RC00066,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158380_k127_1849474_3	1382359.JIAL01000001_gene3009	2.658e-93	317.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria,2JI2Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SRR25158380_k127_1849474_0	234267.Acid_0690	3.647e-176	571.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158380_k127_1854407_0	479434.Sthe_2440	1.098e-147	494.0	COG1505@1|root,COG1505@2|Bacteria,2GBNH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158380_k127_1854407_2	379066.GAU_3819	8.108e-77	260.0	COG0225@1|root,COG0225@2|Bacteria,1ZUAQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158380_k127_1854407_1	1148.1001804	3.393e-121	394.0	COG2267@1|root,COG2267@2|Bacteria,1G000@1117|Cyanobacteria,1H6FP@1142|Synechocystis	1117|Cyanobacteria	I	Alpha/beta hydrolase family	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158380_k127_1854407_3	1382359.JIAL01000001_gene183	6.05e-35	137.0	COG1472@1|root,COG1472@2|Bacteria,3Y2YR@57723|Acidobacteria,2JHNP@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM glycoside hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158380_k127_1855119_2	756272.Plabr_4030	2.072e-39	150.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_1855119_0	32057.KB217478_gene1281	1.101e-179	576.0	COG0654@1|root,COG0654@2|Bacteria,1G5VZ@1117|Cyanobacteria,1HS4Z@1161|Nostocales	1117|Cyanobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158380_k127_1855119_1	518766.Rmar_0109	4.452e-120	393.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1FIXU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_16
SRR25158380_k127_1855850_2	448385.sce8151	3.251e-106	352.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_1855850_0	204669.Acid345_2140	1.08e-118	394.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158380_k127_1855850_4	1380384.JADN01000009_gene257	4.929e-20	98.0	COG1512@1|root,COG1512@2|Bacteria,4NS9C@976|Bacteroidetes,1I3XE@117743|Flavobacteriia	976|Bacteroidetes	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158380_k127_1855850_3	1122613.ATUP01000001_gene1876	4.309e-27	119.0	2EF1A@1|root,338UD@2|Bacteria,1PB4D@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1855850_1	251229.Chro_1581	3.995e-117	394.0	COG1914@1|root,COG1914@2|Bacteria,1GIFV@1117|Cyanobacteria,3VM6A@52604|Pleurocapsales	1117|Cyanobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1855850_5	522772.Dacet_2977	4.664e-12	71.0	COG1664@1|root,COG1664@2|Bacteria,2GFXX@200930|Deferribacteres	200930|Deferribacteres	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158380_k127_1857426_5	1086011.HJ01_03285	4.16e-28	119.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_1857426_0	639030.JHVA01000001_gene3668	0.0	1076.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y950@57723|Acidobacteria	57723|Acidobacteria	G	PEP-utilising enzyme, mobile domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158380_k127_1857426_2	797209.ZOD2009_10355	5.002e-56	203.0	arCOG13341@1|root,arCOG13341@2157|Archaea,2XXWE@28890|Euryarchaeota,23WKG@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1857426_3	351160.RCIX772	2.051e-43	163.0	arCOG10439@1|root,arCOG10439@2157|Archaea,2Y63F@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
SRR25158380_k127_1857426_1	1267535.KB906767_gene4789	7.534e-126	411.0	COG1064@1|root,COG1064@2|Bacteria,3Y34K@57723|Acidobacteria,2JIU5@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158380_k127_1857426_4	760192.Halhy_1783	5.76e-30	125.0	2DI69@1|root,30258@2|Bacteria,4PJ1K@976|Bacteroidetes,1IZ7W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1861281_1	234267.Acid_5841	7.807e-48	183.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158380_k127_1861281_4	1123073.KB899241_gene1839	8.113e-11	68.0	2ATJ5@1|root,31J35@2|Bacteria,1QGTA@1224|Proteobacteria,1TE8Y@1236|Gammaproteobacteria,1X946@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1861281_2	639030.JHVA01000001_gene3133	1.576e-32	136.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria,2JJBC@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1861281_0	204669.Acid345_0136	3.864e-92	309.0	COG1521@1|root,COG1521@2|Bacteria,3Y398@57723|Acidobacteria,2JI76@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158380_k127_1861281_3	329726.AM1_2011	1.572e-25	109.0	COG1819@1|root,COG1819@2|Bacteria,1G3IM@1117|Cyanobacteria	1117|Cyanobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
SRR25158380_k127_1866059_2	632335.Calkr_2451	1.741e-44	168.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,42EZ1@68295|Thermoanaerobacterales	186801|Clostridia	D	Capsular exopolysaccharide family	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
SRR25158380_k127_1866059_0	861299.J421_5610	1.188e-184	589.0	COG1129@1|root,COG1129@2|Bacteria,1ZVAU@142182|Gemmatimonadetes	2|Bacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158380_k127_1866059_1	204669.Acid345_1701	9.339e-117	384.0	COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria,2JI7E@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158380_k127_1869127_2	485913.Krac_12089	5.228e-33	145.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158380_k127_1869127_1	926566.Terro_0568	7.54e-52	193.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria,2JKP9@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
SRR25158380_k127_1869127_0	379066.GAU_3104	2.767e-149	516.0	COG1196@1|root,COG1196@2|Bacteria,1ZU8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1870999_3	278963.ATWD01000001_gene3104	1.271e-06	57.0	2BM5G@1|root,32FP2@2|Bacteria,3Y8NS@57723|Acidobacteria,2JNDM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1870999_4	452637.Oter_2585	3.399e-05	52.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158380_k127_1870999_1	401053.AciPR4_1216	8.404e-45	181.0	COG1290@1|root,COG1290@2|Bacteria,3Y4F0@57723|Acidobacteria,2JKSY@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C
SRR25158380_k127_1870999_2	401053.AciPR4_1215	7.695e-29	121.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158380_k127_1870999_0	1341151.ASZU01000010_gene1916	5.692e-46	171.0	COG3253@1|root,COG3253@2|Bacteria,1VZPB@1239|Firmicutes,4HZ7E@91061|Bacilli,27B36@186824|Thermoactinomycetaceae	91061|Bacilli	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158380_k127_1880739_0	1267535.KB906767_gene5355	2.224e-75	265.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria,2JIC5@204432|Acidobacteriia	204432|Acidobacteriia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158380_k127_1880739_2	984262.SGRA_3519	1.645e-07	59.0	2900C@1|root,2ZMQN@2|Bacteria,4P7Q2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1880739_1	574087.Acear_0054	3.539e-66	232.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WA8W@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM hydrolase, TatD family	yabD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158380_k127_1891320_0	671143.DAMO_2831	2.366e-115	388.0	COG0651@1|root,COG0651@2|Bacteria,2NS4P@2323|unclassified Bacteria	2|Bacteria	CP	Proton-conducting membrane transporter	hyfF	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	iECIAI39_1322.ECIAI39_2625,iZ_1308.Z3746	Proton_antipo_M,Proton_antipo_N
SRR25158380_k127_1891320_3	656024.FsymDg_2288	4.078e-40	156.0	COG4237@1|root,COG4237@2|Bacteria,2HQ3P@201174|Actinobacteria,4EV8A@85013|Frankiales	201174|Actinobacteria	C	Hydrogenase 4 membrane	hycP	GO:0008150,GO:0040007	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_1891320_1	671143.DAMO_2829	1.618e-99	335.0	COG0650@1|root,COG0650@2|Bacteria,2NRV1@2323|unclassified Bacteria	2|Bacteria	C	NADH dehydrogenase	hycD	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158380_k127_1891320_2	671143.DAMO_2828	1.526e-50	186.0	COG0651@1|root,COG0651@2|Bacteria,2NR9Z@2323|unclassified Bacteria	2|Bacteria	CP	Proton-conducting membrane transporter	hyfB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12137,ko:K15828	-	-	-	-	ko00000,ko01000	-	-	iB21_1397.B21_02538,iECBD_1354.ECBD_1002,iECB_1328.ECB_02573,iECD_1391.ECD_02573,iECED1_1282.ECED1_3174,iECO111_1330.ECO111_3443,iECO26_1355.ECO26_3788,iECP_1309.ECP_2686,iEKO11_1354.EKO11_1252,iEcHS_1320.EcHS_A2859,iLF82_1304.LF82_1065,iNRG857_1313.NRG857_13330	Proton_antipo_M,Proton_antipo_N
SRR25158380_k127_189368_1	682795.AciX8_4155	2.275e-156	507.0	COG3533@1|root,COG3533@2|Bacteria,3Y3WA@57723|Acidobacteria,2JKD6@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
SRR25158380_k127_189368_0	240015.ACP_1268	0.0	1050.0	2CDRA@1|root,2Z7QN@2|Bacteria,3Y73N@57723|Acidobacteria,2JMK6@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1896974_3	926566.Terro_3293	3.411e-42	165.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158380_k127_1896974_1	1120973.AQXL01000122_gene179	3.423e-129	428.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,2786F@186823|Alicyclobacillaceae	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRR25158380_k127_1896974_0	1382359.JIAL01000001_gene3006	1.068e-141	456.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158380_k127_1896974_2	204669.Acid345_0970	5.541e-80	273.0	COG1136@1|root,COG1136@2|Bacteria,3Y3JD@57723|Acidobacteria,2JIHH@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_1896974_6	204669.Acid345_0558	1.063e-12	79.0	COG2834@1|root,COG2834@2|Bacteria,3Y4A1@57723|Acidobacteria,2JJ5F@204432|Acidobacteriia	204432|Acidobacteriia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
SRR25158380_k127_1896974_5	1192034.CAP_6755	1.23e-25	111.0	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,42VKR@68525|delta/epsilon subdivisions,2WS4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158380_k127_1896974_4	195522.BD01_1605	7.573e-36	145.0	COG1896@1|root,arCOG04311@2157|Archaea,2XX7G@28890|Euryarchaeota,2440T@183968|Thermococci	183968|Thermococci	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158380_k127_190005_1	1185876.BN8_02393	3.586e-52	189.0	COG4319@1|root,COG4319@2|Bacteria,4NSM4@976|Bacteroidetes,47WQH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_190005_0	1082933.MEA186_06086	7.176e-120	407.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1R20U@1224|Proteobacteria,2U3F2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6
SRR25158380_k127_190005_3	234267.Acid_4535	3.312e-13	75.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158380_k127_190005_2	649764.HMPREF0762_00934	1.032e-17	88.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4CXJD@84998|Coriobacteriia	84998|Coriobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_190005_4	880073.Calab_1008	1.828e-10	69.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158380_k127_1921232_2	234267.Acid_6765	4.811e-06	54.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158380_k127_1921232_1	338966.Ppro_1695	1.893e-85	290.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,43T81@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158380_k127_1921232_0	880073.Calab_3780	6.693e-121	398.0	COG0126@1|root,COG0126@2|Bacteria,2NNN1@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158380_k127_1929763_1	1174528.JH992898_gene1393	4.089e-41	164.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1GJSD@1117|Cyanobacteria,1JJK6@1189|Stigonemataceae	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
SRR25158380_k127_1929763_2	204669.Acid345_1409	1.66e-37	147.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria,2JJIE@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158380_k127_1929763_0	1499967.BAYZ01000095_gene4122	6.793e-60	223.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1929851_2	243164.DET0624	3.111e-22	101.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,34CZJ@301297|Dehalococcoidia	301297|Dehalococcoidia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
SRR25158380_k127_1929851_0	1379698.RBG1_1C00001G1421	8.015e-94	332.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158380_k127_1929851_3	1385518.N798_04180	6.904e-13	79.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4FFWK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158380_k127_1929851_1	864051.BurJ1DRAFT_2047	1.149e-86	303.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VWI8@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158380_k127_1931308_0	1379698.RBG1_1C00001G0518	1.611e-146	484.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158380_k127_1931308_1	251221.35213668	3.686e-117	394.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_1931308_2	68170.KL590515_gene726	0.0004793	45.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4E0U9@85010|Pseudonocardiales	201174|Actinobacteria	L	glycosylase	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158380_k127_1933762_5	1234364.AMSF01000001_gene2351	1.015e-13	77.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,1S4IC@1236|Gammaproteobacteria,1X62F@135614|Xanthomonadales	135614|Xanthomonadales	P	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
SRR25158380_k127_1933762_3	1266925.JHVX01000001_gene2492	3.33e-70	244.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,372UK@32003|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158380_k127_1933762_2	261292.Nit79A3_1268	5.24e-88	296.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,371Q1@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158380_k127_1933762_1	1266925.JHVX01000001_gene2490	5.717e-106	349.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,3729C@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158380_k127_1933762_6	153948.NAL212_1560	9.331e-05	47.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY1Y@28216|Betaproteobacteria,373N5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
SRR25158380_k127_1933762_4	261292.Nit79A3_1271	1.432e-53	192.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158380_k127_1933762_0	1131553.JIBI01000009_gene1231	3.727e-129	415.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,3725U@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158380_k127_1959554_1	1379270.AUXF01000002_gene1539	4.278e-45	169.0	2C7E0@1|root,330TX@2|Bacteria,1ZUQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1959554_5	498761.HM1_2639	4.299e-23	102.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia	186801|Clostridia	O	Xanthine and CO dehydrogenases maturation factor XdhC CoxF	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158380_k127_1959554_4	1157490.EL26_22765	3.236e-35	138.0	COG4539@1|root,COG4539@2|Bacteria,1VJFX@1239|Firmicutes,4HQE3@91061|Bacilli,27A12@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158380_k127_1959554_3	1125863.JAFN01000001_gene373	4.879e-36	147.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3,XdhC_C,XdhC_CoxI
SRR25158380_k127_1959554_0	234267.Acid_1724	3.227e-101	344.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1959554_2	234267.Acid_4126	4.319e-40	153.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1965682_2	204669.Acid345_2137	5.782e-94	320.0	COG0240@1|root,COG0240@2|Bacteria,3Y3ZH@57723|Acidobacteria,2JINS@204432|Acidobacteriia	204432|Acidobacteriia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158380_k127_1965682_1	671143.DAMO_2799	1.95e-94	319.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158380_k127_1965682_0	234267.Acid_7252	0.0	1388.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158380_k127_1965682_3	1341151.ASZU01000004_gene203	2.862e-27	117.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,27BIN@186824|Thermoactinomycetaceae	91061|Bacilli	M	Mur ligase family, glutamate ligase domain	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_1969941_0	986075.CathTA2_1922	1.391e-57	204.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli	91061|Bacilli	I	Dehydrogenase	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_1969941_1	251221.35211166	2.896e-54	214.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRR25158380_k127_1969941_2	671143.DAMO_1345	1.316e-49	191.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158380_k127_1969941_3	1410612.JNKO01000018_gene3051	1.539e-19	92.0	COG2207@1|root,COG2207@2|Bacteria,1V0SK@1239|Firmicutes,24BMU@186801|Clostridia,2PRFQ@265975|Oribacterium	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
SRR25158380_k127_1983579_2	929562.Emtol_3287	8.666e-23	109.0	2AUD4@1|root,31K11@2|Bacteria	2|Bacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158380_k127_1983579_0	404589.Anae109_1057	2.494e-103	340.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_1983579_1	640511.BC1002_4772	1.615e-46	175.0	COG0526@1|root,COG0526@2|Bacteria,1RA5V@1224|Proteobacteria,2VQX7@28216|Betaproteobacteria,1KFIZ@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158380_k127_1983579_3	523841.HFX_0150	0.0001741	52.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTT5@28890|Euryarchaeota,23UP1@183963|Halobacteria	183963|Halobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_1988331_7	344747.PM8797T_15706	8.623e-62	216.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158380_k127_1988331_1	525904.Tter_2662	9.427e-164	522.0	COG2267@1|root,COG2267@2|Bacteria,2NRKH@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158380_k127_1988331_4	1379698.RBG1_1C00001G0608	1.022e-86	328.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
SRR25158380_k127_1988331_8	880072.Desac_2367	1.072e-56	229.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1988331_6	1298867.AUES01000029_gene2400	3.035e-69	271.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_2,TPR_8,Trans_reg_C
SRR25158380_k127_1988331_3	263820.PTO0135	3.178e-88	333.0	COG0515@1|root,arCOG03682@2157|Archaea,2XWZP@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NosD,Pkinase
SRR25158380_k127_1988331_5	1379698.RBG1_1C00001G0607	1.407e-86	308.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158380_k127_1988331_0	204669.Acid345_1052	4.708e-183	602.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_1988331_2	204669.Acid345_1052	5.252e-95	332.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_1988331_9	420662.Mpe_A2300	4.797e-46	171.0	COG0346@1|root,COG0346@2|Bacteria,1RK3P@1224|Proteobacteria,2W3DN@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_2000459_1	945713.IALB_2163	2.039e-73	258.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158380_k127_2000459_0	247490.KSU1_B0566	3.686e-126	421.0	COG2204@1|root,COG2204@2|Bacteria,2J2AC@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
SRR25158380_k127_2010426_0	344747.PM8797T_07137	6.066e-183	592.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes	203682|Planctomycetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
SRR25158380_k127_2015744_0	1298858.AUEL01000011_gene5402	2.961e-14	84.0	COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_2015744_3	401053.AciPR4_4001	9.544e-06	57.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158380_k127_2015744_2	1173027.Mic7113_0279	6.732e-06	54.0	COG2442@1|root,COG2442@2|Bacteria,1G71G@1117|Cyanobacteria,1HBYR@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158380_k127_2018561_1	309807.SRU_1894	1.966e-97	336.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1FJEG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
SRR25158380_k127_2018561_5	313612.L8106_14590	2.412e-10	75.0	COG2730@1|root,COG2931@1|root,COG3386@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
SRR25158380_k127_2018561_3	1535287.JP74_20770	9.177e-15	90.0	2DMII@1|root,32RTH@2|Bacteria,1QW8Y@1224|Proteobacteria,2TWTF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158380_k127_2018561_0	1122138.AQUZ01000019_gene8188	7.135e-155	538.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158380_k127_2018561_6	445335.CBN_1134	7.768e-08	67.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia,36DY0@31979|Clostridiaceae	186801|Clostridia	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3794,SdrD_B
SRR25158380_k127_2018561_4	319236.JCM19294_1035	5.683e-13	84.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,3HJTQ@363408|Nonlabens	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
SRR25158380_k127_2018561_2	1122603.ATVI01000010_gene1066	1.085e-95	328.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RR99@1236|Gammaproteobacteria,1X41W@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158380_k127_2021317_1	1173026.Glo7428_3072	3.978e-126	427.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G0P4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SRR25158380_k127_2021317_0	1267533.KB906733_gene2806	0.0	1508.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158380_k127_2030582_0	1499967.BAYZ01000167_gene6718	1.403e-260	817.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158380_k127_2030582_1	1519464.HY22_10910	7.831e-158	512.0	COG0277@1|root,COG0277@2|Bacteria,1FDCI@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158380_k127_2030582_2	1267535.KB906767_gene3956	3.527e-133	436.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158380_k127_2030582_3	1382359.JIAL01000001_gene476	2.488e-41	156.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158380_k127_2037144_1	1267534.KB906756_gene711	4.983e-71	247.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_2037144_0	443144.GM21_0398	2.053e-75	276.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Ail_Lom,MtrB_PioB
SRR25158380_k127_204312_1	1267535.KB906767_gene906	1.156e-42	168.0	COG4249@1|root,COG4249@2|Bacteria,3Y6DQ@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158380_k127_204312_0	1379270.AUXF01000001_gene2303	9.714e-128	437.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
SRR25158380_k127_204312_2	746697.Aeqsu_0488	2.184e-31	127.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158380_k127_2046911_0	338963.Pcar_1613	3.733e-134	437.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158380_k127_2046911_4	234267.Acid_6464	6.47e-42	170.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_6464|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2046911_3	1267535.KB906767_gene404	5.522e-48	180.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria,2JJ4I@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158380_k127_2046911_5	204669.Acid345_1185	5.08e-34	134.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria,2JP27@204432|Acidobacteriia	204432|Acidobacteriia	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158380_k127_2046911_2	880073.Calab_1913	3.297e-51	195.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158380_k127_2046911_1	459495.SPLC1_S200360	4.455e-62	225.0	COG2199@1|root,COG3706@2|Bacteria,1G35Y@1117|Cyanobacteria,1H9VP@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Response_reg
SRR25158380_k127_2046911_6	344747.PM8797T_09579	6.725e-27	119.0	COG0664@1|root,COG0664@2|Bacteria,2IZG1@203682|Planctomycetes	203682|Planctomycetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_2046911_7	1123368.AUIS01000003_gene1568	1.034e-16	84.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria	1224|Proteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
SRR25158380_k127_2046911_8	443144.GM21_0403	1.799e-15	82.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43VCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_2047150_0	1157490.EL26_19350	3.978e-139	462.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,2798R@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,HAMP,MHYT,PAS,PAS_3,PAS_4,PAS_9
SRR25158380_k127_2047150_1	272134.KB731324_gene2254	7.762e-65	250.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PD40,SpoIIE,TIR_2,WD40
SRR25158380_k127_2048098_1	227882.SAV_115	1.319e-16	82.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR25158380_k127_2048098_2	1267533.KB906733_gene3215	4.773e-14	76.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_2048098_0	502025.Hoch_0087	5.835e-67	248.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2049078_3	204669.Acid345_3132	7.246e-12	67.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158380_k127_2049078_1	1340493.JNIF01000003_gene2431	2.883e-119	405.0	COG1524@1|root,COG1524@2|Bacteria,3Y4MJ@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158380_k127_2049078_2	485913.Krac_5098	7.405e-45	166.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_2049078_5	251221.35211983	1.032e-07	61.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2049078_0	485918.Cpin_4939	6.775e-122	403.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IQQ0@117747|Sphingobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2049078_4	138119.DSY3656	2.666e-09	59.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,261I1@186807|Peptococcaceae	186801|Clostridia	P	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_2057040_0	63737.Npun_F2400	3.598e-252	794.0	COG0531@1|root,COG0531@2|Bacteria,1G1I6@1117|Cyanobacteria,1HK4Y@1161|Nostocales	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2057040_1	204773.HEAR0714	2.655e-17	93.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,47298@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	polysaccharide export protein	epsE	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158380_k127_2058601_5	1262449.CP6013_3777	1.982e-08	61.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,249T1@186801|Clostridia,36HGQ@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Methyltransf_23
SRR25158380_k127_2058601_4	938709.AUSH02000017_gene904	1.334e-21	109.0	COG0438@1|root,COG0438@2|Bacteria,4NKNB@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2058601_0	269797.Mbar_A0237	5.033e-81	282.0	COG0463@1|root,arCOG01381@2157|Archaea,2XYGG@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_2058601_1	56110.Oscil6304_0536	1.976e-65	228.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158380_k127_2058601_2	1123057.P872_00840	1.124e-49	191.0	COG0463@1|root,COG0463@2|Bacteria,4PP9W@976|Bacteroidetes,47YJM@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_2058601_3	443144.GM21_3507	1.857e-47	175.0	COG0438@1|root,COG0438@2|Bacteria,1R6BX@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
SRR25158380_k127_2065014_2	485913.Krac_11202	4.574e-50	182.0	COG3670@1|root,COG3670@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
SRR25158380_k127_2065014_3	1192034.CAP_1637	6.369e-42	158.0	COG4319@1|root,COG4319@2|Bacteria,1N40J@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase,SnoaL_3
SRR25158380_k127_2065014_4	864069.MicloDRAFT_00068200	1.331e-30	125.0	2BW2J@1|root,331CU@2|Bacteria,1N7GK@1224|Proteobacteria,2U7KS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2065014_1	1095769.CAHF01000015_gene2801	4.282e-110	361.0	COG1396@1|root,COG1396@2|Bacteria,1MWUC@1224|Proteobacteria,2VHIE@28216|Betaproteobacteria,473MS@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158380_k127_2065014_0	204669.Acid345_0948	1.446e-163	527.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,3Y578@57723|Acidobacteria,2JKKV@204432|Acidobacteriia	204432|Acidobacteriia	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158380_k127_2065014_5	208444.JNYY01000005_gene6324	1.91e-27	116.0	2CMJR@1|root,32SF0@2|Bacteria,2GW0K@201174|Actinobacteria,4EB52@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2065014_6	401053.AciPR4_2633	1.629e-05	48.0	COG0845@1|root,COG0845@2|Bacteria,3Y2UU@57723|Acidobacteria,2JHUA@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_2071987_3	234267.Acid_3225	3.664e-11	64.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
SRR25158380_k127_2071987_2	204669.Acid345_1052	2.053e-171	567.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_2071987_0	1218084.BBJK01000094_gene6125	7.145e-183	578.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,2VPA8@28216|Betaproteobacteria,1K170@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
SRR25158380_k127_2071987_1	204669.Acid345_2716	9.926e-177	589.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_2074981_0	1122604.JONR01000025_gene4602	1.258e-88	312.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158380_k127_2074981_1	1223410.KN050846_gene2811	5.504e-22	106.0	COG1572@1|root,COG1572@2|Bacteria,4NJ3E@976|Bacteroidetes,1IK72@117743|Flavobacteriia	976|Bacteroidetes	C	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
SRR25158380_k127_2080820_3	861299.J421_4378	8.418e-09	64.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158380_k127_2080820_4	383407.XOC_3142	1.303e-05	57.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158380_k127_2080820_5	580327.Tthe_0345	0.0003295	51.0	COG5662@1|root,COG5662@2|Bacteria,1U13D@1239|Firmicutes,24AF3@186801|Clostridia,42FDE@68295|Thermoanaerobacterales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,DUF4367,zf-HC2
SRR25158380_k127_2080820_2	1382356.JQMP01000003_gene1789	3.363e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2080820_0	671143.DAMO_3033	6.69e-149	479.0	COG0407@1|root,COG1587@1|root,COG0407@2|Bacteria,COG1587@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,4.1.1.37,4.2.1.75	ko:K01599,ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194,R03197,R04972	RC00003,RC00871,RC00872,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	HEM4,Trans_reg_C,URO-D
SRR25158380_k127_2080820_1	1267535.KB906767_gene3344	1.657e-127	415.0	COG0276@1|root,COG0276@2|Bacteria,3Y3B0@57723|Acidobacteria,2JHKQ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158380_k127_2083769_1	234267.Acid_2678	3.719e-120	398.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria	57723|Acidobacteria	GK	PFAM ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158380_k127_2083769_0	1340493.JNIF01000003_gene2760	1.086e-167	551.0	COG2067@1|root,COG2067@2|Bacteria,3Y41G@57723|Acidobacteria	57723|Acidobacteria	I	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_2100568_1	1382356.JQMP01000004_gene233	4.117e-38	147.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi,27XWT@189775|Thermomicrobia	189775|Thermomicrobia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158380_k127_2100568_2	309801.trd_0377	6.562e-34	134.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,27YGN@189775|Thermomicrobia	189775|Thermomicrobia	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158380_k127_2100568_0	251221.35213116	4.721e-100	338.0	COG0793@1|root,COG0793@2|Bacteria,1G58N@1117|Cyanobacteria	1117|Cyanobacteria	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
SRR25158380_k127_2100568_3	649743.HMPREF0972_00732	8.86e-16	85.0	COG1309@1|root,COG1309@2|Bacteria,2HJXI@201174|Actinobacteria,4D4C9@85005|Actinomycetales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158380_k127_2100568_4	234267.Acid_4937	2.931e-07	52.0	COG0387@1|root,COG0387@2|Bacteria,3Y66M@57723|Acidobacteria	57723|Acidobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158380_k127_2101207_1	883112.HMPREF9707_00007	5.297e-07	56.0	2DPFT@1|root,331VS@2|Bacteria,1VK31@1239|Firmicutes	1239|Firmicutes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
SRR25158380_k127_2101207_0	1122604.JONR01000025_gene4602	3.194e-71	265.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158380_k127_2107777_5	204669.Acid345_4380	4.911e-46	180.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,3Y89N@57723|Acidobacteria	57723|Acidobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SRR25158380_k127_2107777_8	1047013.AQSP01000138_gene1046	3.691e-09	69.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRR25158380_k127_2107777_3	204669.Acid345_3981	1.174e-62	220.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria,2JN3W@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_2107777_1	211165.AJLN01000119_gene901	8.42e-147	499.0	COG0642@1|root,COG0784@1|root,COG3447@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,1G09B@1117|Cyanobacteria,1JJQ7@1189|Stigonemataceae	1117|Cyanobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2107777_9	429009.Adeg_1083	0.0001427	48.0	COG1943@1|root,COG1943@2|Bacteria,1V7CE@1239|Firmicutes,24KU3@186801|Clostridia,42JF5@68295|Thermoanaerobacterales	186801|Clostridia	L	transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158380_k127_2107777_2	518766.Rmar_1973	1.333e-99	331.0	COG1878@1|root,COG1878@2|Bacteria,4PIWM@976|Bacteroidetes,1FJPB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative cyclase	-	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158380_k127_2107777_6	861299.J421_5986	2.045e-21	100.0	28V0N@1|root,2ZH49@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2107777_0	1210884.HG799465_gene12236	2.061e-284	893.0	COG1506@1|root,COG1506@2|Bacteria,2IYRT@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRR25158380_k127_2107777_4	216591.BCAL3131	2.663e-60	218.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2VHT7@28216|Betaproteobacteria,1K0NU@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Transport permease protein	tagG	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158380_k127_2107777_7	1499967.BAYZ01000014_gene6405	4.982e-16	82.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
SRR25158380_k127_2115491_0	557598.LHK_01836	1.555e-276	874.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,2KQ8K@206351|Neisseriales	206351|Neisseriales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158380_k127_2115491_2	533240.CRC_03478	7.598e-27	119.0	COG0204@1|root,COG0204@2|Bacteria,1G173@1117|Cyanobacteria,1HKNY@1161|Nostocales	1117|Cyanobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158380_k127_2115491_1	309801.trd_0178	4.427e-68	237.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,27Y5G@189775|Thermomicrobia	189775|Thermomicrobia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158380_k127_2123465_2	211165.AJLN01000098_gene5131	1.46e-35	137.0	COG1741@1|root,COG1741@2|Bacteria,1G41Z@1117|Cyanobacteria,1JJVK@1189|Stigonemataceae	1117|Cyanobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158380_k127_2123465_1	1267535.KB906767_gene730	1.485e-40	157.0	COG1846@1|root,COG1846@2|Bacteria,3Y82F@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
SRR25158380_k127_2123465_0	1267533.KB906740_gene151	5.066e-240	760.0	COG1472@1|root,COG1472@2|Bacteria,3Y2YR@57723|Acidobacteria,2JHNP@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM glycoside hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158380_k127_212666_1	1128427.KB904821_gene205	5.36e-126	417.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158380_k127_212666_2	443143.GM18_0914	6.972e-88	305.0	COG1331@1|root,COG1331@2|Bacteria,1RC7D@1224|Proteobacteria	1224|Proteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K20948	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	-
SRR25158380_k127_212666_4	306281.AJLK01000062_gene4980	7.604e-73	249.0	COG0110@1|root,COG0110@2|Bacteria,1G8S0@1117|Cyanobacteria,1JKNN@1189|Stigonemataceae	1117|Cyanobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158380_k127_212666_0	251229.Chro_0804	4.009e-154	494.0	COG0673@1|root,COG0673@2|Bacteria,1G1CZ@1117|Cyanobacteria,3VK5W@52604|Pleurocapsales	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158380_k127_212666_5	1380390.JIAT01000009_gene362	5.748e-65	235.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158380_k127_212666_3	309801.trd_A0816	6.987e-84	297.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158380_k127_212666_6	234267.Acid_3348	7.56e-59	220.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158380_k127_212666_7	1047013.AQSP01000138_gene1046	4.776e-21	108.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRR25158380_k127_2127580_3	1210884.HG799464_gene10684	2.377e-56	202.0	COG4762@1|root,COG4762@2|Bacteria,2IZUS@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
SRR25158380_k127_2127580_2	1047013.AQSP01000138_gene1079	1.876e-81	280.0	COG4974@1|root,COG4974@2|Bacteria,2NNN8@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158380_k127_2127580_0	234267.Acid_5981	1.317e-108	366.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2127580_1	1340493.JNIF01000003_gene4032	1.053e-81	286.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2129949_1	861299.J421_0531	1.443e-77	270.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
SRR25158380_k127_2129949_3	1242864.D187_003999	8.072e-42	163.0	COG2755@1|root,COG2755@2|Bacteria,1PS6U@1224|Proteobacteria,43315@68525|delta/epsilon subdivisions,2WXTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158380_k127_2129949_2	1267535.KB906767_gene341	2.633e-53	194.0	28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158380_k127_2129949_0	1379270.AUXF01000003_gene3587	1.239e-280	871.0	COG4447@1|root,COG4447@2|Bacteria,1ZSRM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158380_k127_2136973_0	635013.TherJR_2128	2.47e-70	251.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158380_k127_2136973_1	179408.Osc7112_3855	2.641e-18	94.0	COG2214@1|root,COG2214@2|Bacteria,1G6E4@1117|Cyanobacteria,1HB1M@1150|Oscillatoriales	1117|Cyanobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158380_k127_2147679_2	204669.Acid345_4293	2.285e-15	85.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2147679_0	1162668.LFE_1699	2.152e-64	226.0	COG0377@1|root,COG0377@2|Bacteria,3J11S@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158380_k127_2147679_1	1162668.LFE_1700	2.005e-31	128.0	COG0838@1|root,COG0838@2|Bacteria,3J0MS@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158380_k127_2147679_3	204669.Acid345_0831	6.042e-13	82.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
SRR25158380_k127_2151979_1	204669.Acid345_2638	6.5e-90	321.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria,2JHJF@204432|Acidobacteriia	204432|Acidobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158380_k127_2151979_3	269797.Mbar_A0497	6.507e-41	171.0	COG4745@1|root,arCOG00562@2157|Archaea,2XUNV@28890|Euryarchaeota,2NAWY@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_2151979_2	525904.Tter_0360	6.553e-53	209.0	COG5427@1|root,COG5427@2|Bacteria	2|Bacteria	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2151979_0	452637.Oter_3096	1.965e-127	417.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,3K7BN@414999|Opitutae	414999|Opitutae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158380_k127_2161229_1	316067.Geob_0474	4.447e-53	193.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158380_k127_2161229_0	1123248.KB893314_gene3390	1.71e-160	530.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158380_k127_2161229_3	639030.JHVA01000001_gene776	7.499e-34	132.0	COG0713@1|root,COG0713@2|Bacteria,3Y4XI@57723|Acidobacteria,2JJIM@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158380_k127_2161229_4	237368.SCABRO_02001	1.345e-27	120.0	COG0839@1|root,COG0839@2|Bacteria,2J0MC@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158380_k127_2161229_2	240015.ACP_0289	7.54e-52	186.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158380_k127_2170273_5	240015.ACP_1550	4.898e-26	111.0	COG1695@1|root,COG1695@2|Bacteria,3Y4WY@57723|Acidobacteria,2JJYG@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_2170273_1	756067.MicvaDRAFT_1008	1.794e-58	212.0	COG0400@1|root,COG0400@2|Bacteria,1G3RX@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
SRR25158380_k127_2170273_0	1321815.HMPREF9193_01677	9.472e-86	295.0	COG3525@1|root,COG3525@2|Bacteria,2J6I8@203691|Spirochaetes	203691|Spirochaetes	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
SRR25158380_k127_2170273_7	225937.HP15_4166	6.494e-07	56.0	2EKX6@1|root,33EKQ@2|Bacteria,1NCKW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2170273_2	1267534.KB906759_gene1855	3.2e-56	209.0	COG0596@1|root,COG0596@2|Bacteria,3Y89S@57723|Acidobacteria,2JNEB@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_2170273_3	857087.Metme_1081	2.086e-37	153.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1XF3W@135618|Methylococcales	135618|Methylococcales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
SRR25158380_k127_2170273_6	65093.PCC7418_1732	3.094e-24	108.0	COG0517@1|root,COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3829@1|root,COG0517@2|Bacteria,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2170273_4	331869.BAL199_29922	1.433e-36	141.0	COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,4BT3J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent enzyme of the double-stranded beta helix superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2178482_1	394503.Ccel_0452	1.22e-42	164.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,36DEW@31979|Clostridiaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
SRR25158380_k127_2178482_2	1122947.FR7_0499	4.988e-17	89.0	COG1238@1|root,COG1238@2|Bacteria,1UJJC@1239|Firmicutes,4H4J7@909932|Negativicutes	909932|Negativicutes	S	PFAM SNARE associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_2178482_3	204669.Acid345_4653	1.257e-16	88.0	COG1238@1|root,COG1238@2|Bacteria,3Y52F@57723|Acidobacteria,2JJK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_2178482_4	1379698.RBG1_1C00001G0758	3.128e-11	74.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2178482_0	324602.Caur_3748	5.029e-127	429.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158380_k127_2181337_2	638303.Thal_1499	1.793e-14	82.0	COG0265@1|root,COG0265@2|Bacteria,2G3MU@200783|Aquificae	200783|Aquificae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_2181337_1	316274.Haur_4830	1.917e-105	359.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi,3754D@32061|Chloroflexia	32061|Chloroflexia	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158380_k127_2181337_0	1121957.ATVL01000009_gene1201	2.571e-154	497.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158380_k127_2188546_2	644966.Tmar_1104	1.901e-21	98.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158380_k127_2188546_0	1123489.AUAN01000005_gene1616	7.792e-198	634.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4H32N@909932|Negativicutes	909932|Negativicutes	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
SRR25158380_k127_2188546_1	63737.Npun_R1214	2.689e-22	98.0	COG0346@1|root,COG0346@2|Bacteria,1GHQQ@1117|Cyanobacteria,1HPG9@1161|Nostocales	1117|Cyanobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_2189725_11	260799.BAS3643	0.0005003	45.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus	91061|Bacilli	S	ABC-type transport system, periplasmic component surface lipoprotein	tcsA	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
SRR25158380_k127_2189725_4	1278073.MYSTI_06301	2.551e-66	235.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158380_k127_2189725_5	452637.Oter_1625	1.061e-57	204.0	COG0213@1|root,COG0213@2|Bacteria,46TE4@74201|Verrucomicrobia,3K932@414999|Opitutae	414999|Opitutae	F	PFAM glycosyl transferase family 3	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158380_k127_2189725_8	1321782.HMPREF1986_00037	3.574e-47	175.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,2PSCQ@265975|Oribacterium	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158380_k127_2189725_7	338966.Ppro_2969	3.128e-50	186.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,42RJ4@68525|delta/epsilon subdivisions,2WNQ3@28221|Deltaproteobacteria,43SZQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
SRR25158380_k127_2189725_0	204669.Acid345_0189	2.602e-122	406.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria,2JKNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158380_k127_2189725_9	1144275.COCOR_00369	7.035e-34	143.0	COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria,43BX0@68525|delta/epsilon subdivisions,2X77S@28221|Deltaproteobacteria,2YVY8@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2189725_6	497964.CfE428DRAFT_2363	2.817e-53	191.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2189725_10	35754.JNYJ01000039_gene10040	9.49e-30	122.0	COG3011@1|root,COG3011@2|Bacteria,2IFGY@201174|Actinobacteria,4DEKH@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158380_k127_2189725_3	1394178.AWOO02000007_gene3118	8.097e-70	244.0	COG1309@1|root,COG1309@2|Bacteria,2GJES@201174|Actinobacteria,4EIGA@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158380_k127_2189725_1	1120960.ATXG01000017_gene1388	1.16e-101	340.0	COG0702@1|root,COG0702@2|Bacteria,2IQ0Z@201174|Actinobacteria,4FM9R@85023|Microbacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NAD_binding_10
SRR25158380_k127_2189725_2	479434.Sthe_3373	1.167e-75	269.0	COG0654@1|root,COG0654@2|Bacteria,2G66I@200795|Chloroflexi	200795|Chloroflexi	C	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158380_k127_2196505_0	1121428.DESHY_80102___1	9.197e-127	413.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,260R0@186807|Peptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRR25158380_k127_2196505_2	1267533.KB906733_gene3587	2.54e-71	258.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria,2JI1B@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158380_k127_2196505_1	562970.Btus_1531	3.718e-118	392.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,2788P@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158380_k127_2200238_3	926566.Terro_3643	1.045e-05	51.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria,2JJT5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2200238_1	646529.Desaci_3047	6.257e-108	359.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_2200238_2	646529.Desaci_3048	8.971e-22	99.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,26324@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158380_k127_2200238_0	1382359.JIAL01000001_gene2069	3.354e-230	721.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158380_k127_2204001_1	497964.CfE428DRAFT_4490	7.126e-60	215.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158380_k127_2204001_0	497964.CfE428DRAFT_4491	7.415e-233	729.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158380_k127_2204001_3	497964.CfE428DRAFT_4492	1.754e-21	98.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	ATP synthase delta (OSCP) subunit	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158380_k127_2204001_5	1392502.JNIO01000008_gene2833	6.71e-05	52.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes	1239|Firmicutes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01170,iYO844.BSU36850	ATP-synt_B
SRR25158380_k127_2204001_4	497964.CfE428DRAFT_4494	4.256e-16	80.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158380_k127_2204001_2	497964.CfE428DRAFT_4495	5.52e-52	187.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158380_k127_2209913_1	114615.BRADO1556	2.179e-95	330.0	COG2333@1|root,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria,2U6NT@28211|Alphaproteobacteria,3K1MG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_2209913_0	1245469.S58_17860	5.615e-204	657.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria,3JXR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2212877_0	234267.Acid_6651	2.644e-187	603.0	COG0154@1|root,COG0154@2|Bacteria,3Y3E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR25158380_k127_2212877_6	204669.Acid345_1215	1.524e-32	132.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria,2JJFX@204432|Acidobacteriia	204432|Acidobacteriia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158380_k127_2212877_4	1304885.AUEY01000008_gene2079	4.088e-56	199.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MJXP@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158380_k127_2212877_3	1267533.KB906734_gene3652	1.652e-69	244.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_2212877_1	204669.Acid345_1212	1.294e-130	422.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria,2JI6S@204432|Acidobacteriia	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_2212877_5	649747.HMPREF0083_01405	2.991e-34	147.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,276M6@186822|Paenibacillaceae	91061|Bacilli	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
SRR25158380_k127_2212877_2	1123393.KB891316_gene1648	1.608e-86	289.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,2VQHR@28216|Betaproteobacteria,1KRVM@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
SRR25158380_k127_2213638_0	1267534.KB906755_gene4695	3.3e-322	1015.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria,2JK9M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_2213638_1	234267.Acid_7893	8.055e-44	166.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019,ko:K13292	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158380_k127_2220662_3	1454004.AW11_01665	1.876e-91	309.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158380_k127_2220662_4	1267534.KB906754_gene3080	3.021e-49	186.0	COG5662@1|root,COG5662@2|Bacteria,3Y807@57723|Acidobacteria,2JN34@204432|Acidobacteriia	204432|Acidobacteriia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158380_k127_2220662_5	1267534.KB906754_gene3081	3.775e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,3Y7HT@57723|Acidobacteria,2JMNZ@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2220662_0	886293.Sinac_0884	2.269e-195	620.0	COG1858@1|root,COG1858@2|Bacteria,2IY6Q@203682|Planctomycetes	203682|Planctomycetes	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2220662_1	1126627.BAWE01000002_gene217	1.079e-124	417.0	COG1999@1|root,COG1999@2|Bacteria,1RGQ1@1224|Proteobacteria,2UBKZ@28211|Alphaproteobacteria,3K00X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2220662_6	1536774.H70357_31445	3.157e-43	159.0	COG0537@1|root,COG0537@2|Bacteria,1V9QX@1239|Firmicutes,4HJD9@91061|Bacilli,26Y6U@186822|Paenibacillaceae	91061|Bacilli	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158380_k127_2220662_7	448385.sce6756	9.59e-29	127.0	2E0EH@1|root,2ZZNI@2|Bacteria,1Q8YZ@1224|Proteobacteria,438YN@68525|delta/epsilon subdivisions,2X441@28221|Deltaproteobacteria,2YY76@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2220662_2	204669.Acid345_3144	2.308e-103	353.0	COG1680@1|root,COG1680@2|Bacteria,3Y7DP@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_2226467_1	861299.J421_6102	3.133e-63	219.0	COG2382@1|root,COG2382@2|Bacteria,1ZUJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_2226467_0	1267535.KB906767_gene2552	0.0	1289.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria,2JMMF@204432|Acidobacteriia	204432|Acidobacteriia	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158380_k127_2226467_2	1122605.KB893629_gene4181	1.629e-45	174.0	2C312@1|root,2Z7N1@2|Bacteria,4NFNW@976|Bacteroidetes,1IZ1X@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2226467_4	204669.Acid345_4058	2.969e-29	126.0	COG1737@1|root,COG1737@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158380_k127_2226467_3	204669.Acid345_3841	1.805e-40	162.0	COG1629@1|root,COG4771@2|Bacteria	204669.Acid345_3841|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2227816_0	215803.DB30_5624	4.822e-196	619.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42PXH@68525|delta/epsilon subdivisions,2WKEX@28221|Deltaproteobacteria,2YTWX@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158380_k127_2227816_1	479434.Sthe_2909	1.687e-156	507.0	COG1012@1|root,COG1012@2|Bacteria,2G7YU@200795|Chloroflexi,27Y0H@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158380_k127_2227816_2	357808.RoseRS_2094	5.673e-132	438.0	COG0318@1|root,COG0318@2|Bacteria,2G7VC@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158380_k127_223171_3	1410622.JNKY01000019_gene1795	3.428e-09	66.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,27J6G@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158380_k127_223171_0	661478.OP10G_1986	1.473e-132	437.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3,Beta-lactamase
SRR25158380_k127_223171_2	671143.DAMO_0302	3.012e-10	71.0	COG0457@1|root,COG0457@2|Bacteria	671143.DAMO_0302|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_223171_1	234267.Acid_5431	3.844e-41	161.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_2235563_1	760192.Halhy_5620	4.737e-142	464.0	COG0477@1|root,COG2814@2|Bacteria,4PNZI@976|Bacteroidetes	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_2235563_0	452637.Oter_1898	3.38e-231	742.0	COG0577@1|root,COG0577@2|Bacteria	452637.Oter_1898|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2235563_2	204669.Acid345_1052	3.715e-80	282.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_2237611_0	546271.Selsp_1899	8.931e-85	285.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4H20D@909932|Negativicutes	909932|Negativicutes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158380_k127_2237611_2	869210.Marky_0690	3.042e-09	70.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1,Peptidase_MA_2
SRR25158380_k127_2237611_1	177437.HRM2_27830	8.194e-45	168.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria,2MK33@213118|Desulfobacterales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
SRR25158380_k127_2238939_0	671143.DAMO_2283	7.024e-243	760.0	COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria	2|Bacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158380_k127_2238939_1	1254432.SCE1572_29320	3.68e-53	191.0	COG2259@1|root,COG2259@2|Bacteria,1PT6T@1224|Proteobacteria,434W0@68525|delta/epsilon subdivisions,2WZ73@28221|Deltaproteobacteria,2Z1GN@29|Myxococcales	28221|Deltaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158380_k127_2238939_2	1267535.KB906767_gene552	1.83e-46	178.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Y0@57723|Acidobacteria,2JIYU@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_224084_3	1333856.L686_08220	4.005e-07	51.0	2E30H@1|root,32Y10@2|Bacteria,1N7X0@1224|Proteobacteria,1SIAC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_224084_0	1382359.JIAL01000001_gene2381	3.871e-199	638.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158380_k127_224084_1	1078085.HMPREF1210_03371	7.68e-11	73.0	2E9CG@1|root,333K5@2|Bacteria,1V87Y@1239|Firmicutes,4HIGZ@91061|Bacilli,26FG7@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIMP
SRR25158380_k127_224084_2	1120960.ATXG01000005_gene2462	4.406e-10	70.0	COG4932@1|root,COG4932@2|Bacteria,2IAMD@201174|Actinobacteria,4FRAH@85023|Microbacteriaceae	201174|Actinobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SdrD_B
SRR25158380_k127_2245825_0	1057002.KB905370_gene4587	1.533e-120	406.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2V7KJ@28211|Alphaproteobacteria,4BJYD@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_2246042_1	1126627.BAWE01000002_gene218	2.891e-69	245.0	2DNPP@1|root,32YG6@2|Bacteria,1N6AN@1224|Proteobacteria,2UGF4@28211|Alphaproteobacteria,3K1EJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158380_k127_2246042_0	1126627.BAWE01000002_gene219	9.593e-142	461.0	COG2304@1|root,COG2304@2|Bacteria,1R88T@1224|Proteobacteria,2U11Q@28211|Alphaproteobacteria,3JX3K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	Tyrosinase
SRR25158380_k127_2246042_2	278963.ATWD01000002_gene765	1.895e-13	81.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_2250626_3	234267.Acid_6490	1.079e-47	179.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158380_k127_2250626_1	1121468.AUBR01000014_gene2214	9.181e-70	245.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158380_k127_2250626_0	204669.Acid345_2369	3.683e-158	507.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_2250626_2	401526.TcarDRAFT_1687	2.465e-56	201.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H1WI@909932|Negativicutes	909932|Negativicutes	E	LAO AO transport system	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158380_k127_2252569_0	335543.Sfum_1457	0.0	1027.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_2252569_1	880072.Desac_2384	1.761e-108	366.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_2254416_1	313628.LNTAR_05834	9.757e-40	154.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,FR47
SRR25158380_k127_2254416_0	247490.KSU1_C0443	9.258e-201	642.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
SRR25158380_k127_2262460_5	644282.Deba_1516	1.802e-31	126.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158380_k127_2262460_3	1379698.RBG1_1C00001G0519	4.189e-50	190.0	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
SRR25158380_k127_2262460_0	1117319.PSPO_14244	2.517e-76	266.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2Q1G4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158380_k127_2262460_7	1379270.AUXF01000001_gene2021	4.765e-08	57.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158380_k127_2262460_1	1122179.KB890422_gene2225	6.355e-75	267.0	COG0596@1|root,COG0596@2|Bacteria,4NQYB@976|Bacteroidetes	976|Bacteroidetes	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158380_k127_2262460_2	67257.JODR01000026_gene2799	1.295e-50	183.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158380_k127_2262460_4	1499967.BAYZ01000013_gene6453	3.559e-49	183.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2265237_5	316274.Haur_1077	9.258e-05	55.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,2G6X8@200795|Chloroflexi,3758G@32061|Chloroflexia	32061|Chloroflexia	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc
SRR25158380_k127_2265237_3	391625.PPSIR1_24749	9.491e-44	183.0	COG0437@1|root,COG0664@1|root,COG0437@2|Bacteria,COG0664@2|Bacteria,1QZTQ@1224|Proteobacteria,43CNM@68525|delta/epsilon subdivisions,2X2C7@28221|Deltaproteobacteria,2YX3F@29|Myxococcales	28221|Deltaproteobacteria	CT	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,cNMP_binding
SRR25158380_k127_2265237_1	478741.JAFS01000002_gene862	5.197e-65	236.0	COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,37G7H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158380_k127_2265237_0	204669.Acid345_1988	1.857e-77	279.0	COG0747@1|root,COG0747@2|Bacteria,3Y44K@57723|Acidobacteria,2JHM9@204432|Acidobacteriia	204432|Acidobacteriia	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158380_k127_2265237_4	404589.Anae109_1413	8.951e-37	146.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WQ0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158380_k127_2265237_2	251221.35214700	8.381e-51	196.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158380_k127_2269865_8	589865.DaAHT2_2615	7.741e-11	65.0	2EH60@1|root,33AXW@2|Bacteria,1NGBT@1224|Proteobacteria,42X9U@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF2798)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
SRR25158380_k127_2269865_0	243231.GSU0801	1.035e-155	505.0	COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria	1224|Proteobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
SRR25158380_k127_2269865_4	251229.Chro_5576	7.143e-69	244.0	COG2207@1|root,COG2207@2|Bacteria,1G0TY@1117|Cyanobacteria,3VKYM@52604|Pleurocapsales	1117|Cyanobacteria	K	COGs COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158380_k127_2269865_6	1116472.MGMO_55c00340	9.926e-31	126.0	2B0DW@1|root,31SR8@2|Bacteria,1RHKN@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SRR25158380_k127_2269865_5	1210884.HG799474_gene15144	7.906e-40	154.0	COG0251@1|root,COG0251@2|Bacteria,2J1GN@203682|Planctomycetes	203682|Planctomycetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158380_k127_2269865_9	84531.JMTZ01000065_gene1877	0.0001348	45.0	COG1396@1|root,COG1396@2|Bacteria,1MWUC@1224|Proteobacteria,1S1BS@1236|Gammaproteobacteria,1X5KY@135614|Xanthomonadales	135614|Xanthomonadales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158380_k127_2269865_3	1163408.UU9_06579	4.365e-80	274.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,1S2C1@1236|Gammaproteobacteria,1X70C@135614|Xanthomonadales	135614|Xanthomonadales	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158380_k127_2269865_2	84531.JMTZ01000065_gene1877	7.626e-104	350.0	COG1396@1|root,COG1396@2|Bacteria,1MWUC@1224|Proteobacteria,1S1BS@1236|Gammaproteobacteria,1X5KY@135614|Xanthomonadales	135614|Xanthomonadales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158380_k127_2269865_1	84531.JMTZ01000022_gene4177	5.823e-126	412.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RZC3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158380_k127_2269865_7	1267534.KB906754_gene2832	3.797e-21	95.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
SRR25158380_k127_2270081_1	1382359.JIAL01000001_gene2036	5.309e-42	166.0	COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria,3Y3Z6@57723|Acidobacteria,2JIQG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_2270081_2	443143.GM18_1590	7.073e-12	78.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	A	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
SRR25158380_k127_2270081_0	204669.Acid345_0328	1.621e-134	436.0	COG3534@1|root,COG3534@2|Bacteria,3Y48A@57723|Acidobacteria,2JKQ1@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SRR25158380_k127_2271035_1	1267535.KB906767_gene1668	1.836e-72	254.0	COG0179@1|root,COG0179@2|Bacteria,3Y4BX@57723|Acidobacteria,2JJD1@204432|Acidobacteriia	204432|Acidobacteriia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	ko:K18336	ko00051,ko01120,map00051,map01120	-	R10691	RC00326,RC03236	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158380_k127_2271035_0	639030.JHVA01000001_gene2965	4.683e-135	451.0	COG0591@1|root,COG0591@2|Bacteria,3Y4WN@57723|Acidobacteria,2JJVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158380_k127_2271035_2	1173022.Cri9333_1272	2.478e-16	91.0	COG1649@1|root,COG3266@1|root,COG1649@2|Bacteria,COG3266@2|Bacteria,1G2UW@1117|Cyanobacteria,1H6Z8@1150|Oscillatoriales	1117|Cyanobacteria	NU	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
SRR25158380_k127_2271611_1	886293.Sinac_1403	1.255e-30	123.0	COG1146@1|root,COG1146@2|Bacteria,2J013@203682|Planctomycetes	203682|Planctomycetes	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SRR25158380_k127_2271611_3	153721.MYP_3074	1.56e-16	88.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47R8S@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
SRR25158380_k127_2271611_2	243231.GSU0899	2.039e-28	131.0	COG4399@1|root,COG4399@2|Bacteria,1R42C@1224|Proteobacteria,42Q2W@68525|delta/epsilon subdivisions,2WJIA@28221|Deltaproteobacteria,43S0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158380_k127_2271611_0	234267.Acid_7272	8.83e-57	205.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
SRR25158380_k127_2271644_11	745776.DGo_CA0097	4.382e-30	128.0	COG1975@1|root,COG1975@2|Bacteria,1WIZE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	XdhC Rossmann domain	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
SRR25158380_k127_2271644_3	861299.J421_2164	7.861e-104	349.0	COG3552@1|root,COG3552@2|Bacteria	2|Bacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158380_k127_2271644_1	861299.J421_2163	3.884e-118	387.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158380_k127_2271644_8	1206731.BAGB01000170_gene4461	3.576e-45	171.0	COG2068@1|root,COG2068@2|Bacteria,2HHWD@201174|Actinobacteria,4G1AJ@85025|Nocardiaceae	201174|Actinobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158380_k127_2271644_5	1123228.AUIH01000004_gene1087	2.548e-72	256.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,1MWFN@1224|Proteobacteria,1RV4F@1236|Gammaproteobacteria,1XQ7H@135619|Oceanospirillales	135619|Oceanospirillales	O	XdhC Rossmann domain	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
SRR25158380_k127_2271644_10	768671.ThimaDRAFT_4674	1.501e-31	124.0	COG1598@1|root,COG1598@2|Bacteria,1NFAZ@1224|Proteobacteria,1SFC1@1236|Gammaproteobacteria,1WZCW@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2271644_0	518766.Rmar_2766	0.0	1306.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158380_k127_2271644_4	309801.trd_A0565	1.454e-75	258.0	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
SRR25158380_k127_2271644_2	1382306.JNIM01000001_gene2454	3.587e-104	346.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158380_k127_2271644_9	502025.Hoch_4562	6.153e-41	159.0	COG3427@1|root,COG3427@2|Bacteria,1PJ50@1224|Proteobacteria,4331V@68525|delta/epsilon subdivisions,2WYE1@28221|Deltaproteobacteria,2Z1MD@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRR25158380_k127_2271644_6	1382356.JQMP01000003_gene2203	2.153e-60	220.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi,27XYI@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2271644_7	666686.B1NLA3E_19575	1.996e-46	176.0	COG2215@1|root,COG2215@2|Bacteria,1VA77@1239|Firmicutes,4HM1V@91061|Bacilli,1ZC90@1386|Bacillus	91061|Bacilli	S	PFAM Nickel cobalt transporter, high-affinity	ureH	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
SRR25158380_k127_2274800_3	330214.NIDE3031	1.381e-33	134.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,3J0PZ@40117|Nitrospirae	40117|Nitrospirae	EM	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
SRR25158380_k127_2274800_4	1333523.L593_04980	5.246e-29	126.0	COG0451@1|root,arCOG01369@2157|Archaea,2Y7SY@28890|Euryarchaeota,23SBI@183963|Halobacteria	183963|Halobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158380_k127_2274800_0	204669.Acid345_1065	4.276e-152	514.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158380_k127_2274800_5	936375.HMPREF1152_0772	1.777e-21	101.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WCNM@538999|Clostridiales incertae sedis	186801|Clostridia	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158380_k127_2274800_1	484770.UFO1_1922	5.988e-126	417.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4H31K@909932|Negativicutes	909932|Negativicutes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158380_k127_2274800_7	204669.Acid345_2334	1.081e-12	79.0	COG2948@1|root,COG2948@2|Bacteria,3Y81Q@57723|Acidobacteria,2JN9S@204432|Acidobacteriia	204432|Acidobacteriia	U	multi-organism process	-	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
SRR25158380_k127_2274800_2	234267.Acid_0601	1.648e-61	225.0	COG1912@1|root,COG1912@2|Bacteria,3Y50E@57723|Acidobacteria	57723|Acidobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158380_k127_2274800_6	1123239.KB898623_gene1305	5.994e-19	89.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158380_k127_2277405_2	234267.Acid_0096	2.553e-24	117.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
SRR25158380_k127_2277405_0	1122179.KB890422_gene2225	4.022e-98	338.0	COG0596@1|root,COG0596@2|Bacteria,4NQYB@976|Bacteroidetes	976|Bacteroidetes	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158380_k127_2277405_3	861299.J421_1409	9.556e-23	104.0	2EV6U@1|root,33NMK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2278786_0	485913.Krac_11786	8.924e-156	512.0	COG0249@1|root,COG0249@2|Bacteria,2G8CJ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA mismatch repair protein MutS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
SRR25158380_k127_2278786_1	1267535.KB906767_gene4070	6.53e-42	165.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
SRR25158380_k127_2278786_2	404589.Anae109_3248	1.837e-11	64.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria	1224|Proteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158380_k127_2282662_0	234267.Acid_5235	4.72e-147	480.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158380_k127_2282662_1	234267.Acid_5234	1.331e-44	165.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158380_k127_2283389_2	234267.Acid_6939	1.259e-14	78.0	COG1629@1|root,COG4771@2|Bacteria,3Y2MF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_2283389_1	179408.Osc7112_0805	1.228e-62	223.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HBKK@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158380_k127_2283389_0	1125863.JAFN01000001_gene1462	1.084e-202	642.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158380_k127_2285484_2	204669.Acid345_0708	5.416e-65	224.0	COG1100@1|root,COG1100@2|Bacteria,3Y7CQ@57723|Acidobacteria	57723|Acidobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
SRR25158380_k127_2285484_4	69014.TK2214	5.203e-14	79.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,2432R@183968|Thermococci	183968|Thermococci	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158380_k127_2285484_1	585503.HMPREF7545_1880	1.677e-104	349.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H1WD@909932|Negativicutes	909932|Negativicutes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158380_k127_2285484_5	1415756.JQMY01000001_gene941	4.02e-10	70.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,2PCWI@252301|Oceanicola	28211|Alphaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158380_k127_2285484_0	1131269.AQVV01000002_gene1185	2.679e-135	438.0	COG2255@1|root,COG2255@2|Bacteria	2|Bacteria	L	four-way junction helicase activity	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158380_k127_2285484_3	316067.Geob_2324	2.373e-50	187.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,43U6G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158380_k127_2288776_1	313606.M23134_01906	6.282e-12	67.0	COG4977@1|root,COG4977@2|Bacteria,4PMD8@976|Bacteroidetes,47Q18@768503|Cytophagia	2|Bacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158380_k127_2288776_0	1254432.SCE1572_49835	1.96e-245	771.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158380_k127_2293190_0	1267535.KB906767_gene5021	7.183e-188	597.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	204432|Acidobacteriia	J	class II (D K	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_2293190_6	102125.Xen7305DRAFT_00028560	1.548e-36	147.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ubiE_2	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158380_k127_2293190_7	945713.IALB_2664	1.172e-29	126.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158380_k127_2293190_4	1122182.KB903834_gene5898	1.535e-87	297.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria,4DJFC@85008|Micromonosporales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR25158380_k127_2293190_2	1120973.AQXL01000117_gene347	2.404e-96	327.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,2784I@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the arginase family	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158380_k127_2293190_1	204669.Acid345_4592	9.164e-114	377.0	COG1181@1|root,COG1181@2|Bacteria,3Y3HW@57723|Acidobacteria,2JI4N@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158380_k127_2293190_8	204669.Acid345_2506	1.223e-27	123.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158380_k127_2293190_3	1122176.KB903532_gene2606	4.398e-89	305.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158380_k127_2293190_9	56780.SYN_01734	7.601e-25	109.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2MS8A@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158380_k127_2293190_5	204669.Acid345_4232	9.829e-60	223.0	COG0793@1|root,COG0793@2|Bacteria,3Y3A7@57723|Acidobacteria,2JHJK@204432|Acidobacteriia	204432|Acidobacteriia	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158380_k127_22938_0	330214.NIDE3498	4.006e-213	682.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
SRR25158380_k127_22938_9	479432.Sros_5880	7.581e-32	130.0	2E5J0@1|root,330AB@2|Bacteria,2I805@201174|Actinobacteria,4ERAW@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_22938_4	1122603.ATVI01000011_gene2102	2.073e-82	287.0	COG4222@1|root,COG4222@2|Bacteria,1MVDD@1224|Proteobacteria,1RYXE@1236|Gammaproteobacteria,1X7TW@135614|Xanthomonadales	135614|Xanthomonadales	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
SRR25158380_k127_22938_7	485913.Krac_0295	1.869e-47	178.0	COG1651@1|root,COG1651@2|Bacteria,2G9C9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_22938_6	1121920.AUAU01000004_gene840	2.384e-49	181.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
SRR25158380_k127_22938_2	63737.Npun_R2975	6.547e-120	391.0	28IG1@1|root,2Z8HJ@2|Bacteria,1G0EA@1117|Cyanobacteria,1HJM2@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_22938_8	290315.Clim_1144	6.379e-36	139.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
SRR25158380_k127_22938_3	1278073.MYSTI_04002	5.997e-103	342.0	COG0702@1|root,COG0702@2|Bacteria,1N8V3@1224|Proteobacteria,4307M@68525|delta/epsilon subdivisions,2WVDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_22938_1	1267535.KB906767_gene1084	5.765e-127	421.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
SRR25158380_k127_22938_5	880072.Desac_2385	2.517e-59	209.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Hydrophobe amphiphile Efflux-1 (HAE1) family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_2295678_5	443144.GM21_0228	6.699e-16	89.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43UDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_2295678_3	317936.Nos7107_3919	1.092e-19	100.0	COG1876@1|root,COG1876@2|Bacteria,1G4P0@1117|Cyanobacteria,1HIMP@1161|Nostocales	1117|Cyanobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	-	-	-	-	-	-	-	-	-	-	VanY
SRR25158380_k127_2295678_2	1123508.JH636440_gene2323	3.911e-56	217.0	COG0515@1|root,COG0515@2|Bacteria,2IXRH@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,LRR_6,Pkinase
SRR25158380_k127_2295678_4	1125701.HMPREF1221_01400	4.444e-17	89.0	COG3762@1|root,COG3762@2|Bacteria,2J6T4@203691|Spirochaetes	203691|Spirochaetes	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158380_k127_2295678_1	1144275.COCOR_00645	5.903e-92	321.0	COG4395@1|root,COG4395@2|Bacteria	2|Bacteria	S	Tim44	MA20_24770	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	Tim44
SRR25158380_k127_2295678_0	861299.J421_1260	1.273e-114	387.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_2295678_6	485917.Phep_2677	0.0009967	46.0	COG0612@1|root,COG0612@2|Bacteria,4NHQP@976|Bacteroidetes,1IVW0@117747|Sphingobacteriia	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_2295998_2	1158760.AQXP01000034_gene2214	1.438e-16	86.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
SRR25158380_k127_2295998_1	204669.Acid345_2199	8.282e-70	246.0	COG1725@1|root,COG1725@2|Bacteria,3Y8PU@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158380_k127_2295998_0	1191523.MROS_0617	2.708e-82	282.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158380_k127_2304923_2	1382359.JIAL01000001_gene2600	3.217e-11	71.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158380_k127_2304923_1	1121920.AUAU01000009_gene1864	6.287e-43	179.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2304923_0	1121920.AUAU01000013_gene1740	1.632e-84	290.0	COG2234@1|root,COG2234@2|Bacteria,3Y3KE@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158380_k127_2315735_2	555088.DealDRAFT_1265	1.761e-15	85.0	2A5Z5@1|root,30URA@2|Bacteria,1V56B@1239|Firmicutes,24IP8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2315735_0	1303518.CCALI_01492	3.782e-113	373.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158380_k127_2315735_1	1267535.KB906767_gene544	2.582e-96	341.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_2326209_0	330214.NIDE0582	1.574e-82	303.0	COG1752@1|root,COG3153@1|root,COG1752@2|Bacteria,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.59,2.3.1.82	ko:K14658,ko:K17840,ko:K18815	-	M00664	-	-	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Patatin
SRR25158380_k127_2329084_3	1267535.KB906767_gene2786	3.4e-31	128.0	2DB97@1|root,32TX2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2329084_2	596151.DesfrDRAFT_1779	2.934e-32	135.0	COG0500@1|root,COG2226@2|Bacteria,1Q4FT@1224|Proteobacteria,42Z3X@68525|delta/epsilon subdivisions,2WTJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2329084_1	335659.S23_05200	1.571e-41	157.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158380_k127_2329084_0	1128421.JAGA01000002_gene876	2.004e-48	177.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Glycos_transf_2,HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158380_k127_2331696_0	1121406.JAEX01000005_gene3039	3.015e-207	660.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2M9EY@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158380_k127_2331696_1	1382359.JIAL01000001_gene642	1.451e-72	255.0	COG0583@1|root,COG0583@2|Bacteria,3Y31P@57723|Acidobacteria,2JIC0@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158380_k127_2331696_2	661478.OP10G_1219	7.993e-10	60.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_2332691_0	316274.Haur_0717	3.514e-43	169.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158380_k127_2332691_2	326427.Cagg_3733	5.543e-23	106.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158380_k127_2332691_1	1267535.KB906767_gene3078	8.245e-41	167.0	COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria	57723|Acidobacteria	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158380_k127_2336839_0	378806.STAUR_1043	1.631e-07	64.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	spoIVB	-	3.4.21.116,3.4.24.3	ko:K01387,ko:K06399	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	Peptidase_M61,Peptidase_M9,Peptidase_M9_N
SRR25158380_k127_2336839_1	1198114.AciX9_1138	0.0007327	51.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
SRR25158380_k127_2339076_1	204669.Acid345_0995	1.079e-152	493.0	COG3191@1|root,COG3191@2|Bacteria,3Y699@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158380_k127_2339076_2	269799.Gmet_3488	9.582e-116	383.0	2DBVK@1|root,2ZBBH@2|Bacteria,1PWZS@1224|Proteobacteria,432W2@68525|delta/epsilon subdivisions,2WXWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158380_k127_2339076_3	1120999.JONM01000001_gene1199	1.087e-60	221.0	28I9H@1|root,2Z8C6@2|Bacteria,1R4JY@1224|Proteobacteria,2VVXD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2339076_0	1340493.JNIF01000004_gene294	7.156e-192	610.0	COG0591@1|root,COG0591@2|Bacteria,3Y4WN@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158380_k127_2346896_2	1459636.NTE_03091	4.8e-79	268.0	COG0431@1|root,arCOG04624@2157|Archaea,41T7Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
SRR25158380_k127_2346896_3	118173.KB235914_gene3657	6.995e-41	164.0	COG0491@1|root,COG0491@2|Bacteria,1G455@1117|Cyanobacteria,1HDSU@1150|Oscillatoriales	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_2346896_0	1183438.GKIL_2224	5.043e-250	784.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
SRR25158380_k127_2346896_4	639030.JHVA01000001_gene697	0.0002198	49.0	2FDUY@1|root,345VJ@2|Bacteria,3Y8EG@57723|Acidobacteria,2JNMJ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2346896_1	748280.NH8B_2766	4.048e-225	719.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158380_k127_234977_0	667015.Bacsa_2391	2.163e-06	59.0	COG5434@1|root,COG5434@2|Bacteria,4NICS@976|Bacteroidetes,2FMGC@200643|Bacteroidia,4APJS@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
SRR25158380_k127_2351139_3	927677.ALVU02000001_gene1926	3.529e-26	109.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria	1117|Cyanobacteria	S	small GTP-binding protein domain	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Ras
SRR25158380_k127_2351139_5	32057.KB217478_gene3618	2.245e-15	86.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
SRR25158380_k127_2351139_6	331869.BAL199_09138	5.886e-13	72.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,4BQMS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158380_k127_2351139_4	1042326.AZNV01000030_gene3627	1.14e-23	106.0	2EAFX@1|root,32G8D@2|Bacteria,1RJFV@1224|Proteobacteria,2U9DS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2351139_1	234267.Acid_4457	9.001e-101	334.0	COG0546@1|root,COG0546@2|Bacteria,3Y4NY@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158380_k127_2351139_0	661478.OP10G_0585	3.271e-180	577.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158380_k127_2351139_2	1303518.CCALI_02571	9.372e-36	138.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158380_k127_2354085_2	639030.JHVA01000001_gene3038	2.734e-10	64.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_2354085_1	1123276.KB893260_gene2582	4.325e-89	304.0	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,47M0T@768503|Cytophagia	976|Bacteroidetes	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
SRR25158380_k127_2354085_0	234267.Acid_1098	6.122e-120	396.0	COG2755@1|root,COG2755@2|Bacteria,3Y99T@57723|Acidobacteria	57723|Acidobacteria	E	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
SRR25158380_k127_2355165_2	1379698.RBG1_1C00001G0336	1.195e-36	149.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158380_k127_2355165_0	452637.Oter_3899	4.482e-152	499.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46UA9@74201|Verrucomicrobia,3K7MZ@414999|Opitutae	414999|Opitutae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
SRR25158380_k127_2355165_1	196367.JNFG01000011_gene6125	6.138e-52	191.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K3DU@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,PAS_9
SRR25158380_k127_2355165_5	743719.PaelaDRAFT_1084	1.468e-17	96.0	2AKFW@1|root,31B7M@2|Bacteria,1TZN5@1239|Firmicutes,4I8X9@91061|Bacilli,270NP@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158380_k127_2355165_4	290397.Adeh_2374	2.421e-23	114.0	2ER1F@1|root,33IKZ@2|Bacteria,1PANM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2355165_3	1089545.KB913037_gene6803	1.59e-27	116.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4DZWC@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
SRR25158380_k127_2359434_3	573061.Clocel_0696	0.0001391	53.0	COG0457@1|root,COG0457@2|Bacteria	573061.Clocel_0696|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2359434_2	1382359.JIAL01000001_gene2531	6.096e-29	135.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2359434_0	234267.Acid_3494	2.024e-84	294.0	COG0457@1|root,COG0457@2|Bacteria,3Y6B2@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158380_k127_2359434_1	234267.Acid_3491	3.7e-48	187.0	COG0457@1|root,COG0457@2|Bacteria,3Y8AI@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158380_k127_2363061_2	1469607.KK073768_gene352	2.991e-24	109.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8,Trypsin_2
SRR25158380_k127_2363061_0	682795.AciX8_0643	8.84e-41	158.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2363061_4	1541065.JRFE01000035_gene2803	1.488e-08	56.0	COG4977@1|root,COG4977@2|Bacteria,1G1HG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158380_k127_2363061_1	1173024.KI912153_gene37	2.933e-25	116.0	COG4977@1|root,COG4977@2|Bacteria,1G1HG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158380_k127_2363061_3	1449065.JMLL01000018_gene1826	1.827e-22	99.0	COG4566@1|root,COG4566@2|Bacteria,1R3SP@1224|Proteobacteria,2TQZN@28211|Alphaproteobacteria,43NC3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_2363848_1	391625.PPSIR1_18847	6.265e-27	115.0	2AH2G@1|root,317BP@2|Bacteria,1PYMG@1224|Proteobacteria,435FZ@68525|delta/epsilon subdivisions,2WZTG@28221|Deltaproteobacteria,2Z2Q9@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2363848_0	1379270.AUXF01000004_gene3287	2.847e-100	342.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
SRR25158380_k127_2363848_2	555779.Dthio_PD1758	2.56e-25	107.0	COG1598@1|root,COG1598@2|Bacteria,1P3HP@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2363848_3	631362.Thi970DRAFT_01754	2.71e-25	106.0	COG1724@1|root,COG1724@2|Bacteria,1NA6Q@1224|Proteobacteria,1SUS7@1236|Gammaproteobacteria,1X1TQ@135613|Chromatiales	135613|Chromatiales	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158380_k127_2363848_4	412597.AEPN01000005_gene1500	6.323e-08	55.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2PUGP@265|Paracoccus	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158380_k127_2366341_0	234267.Acid_2606	6.149e-245	770.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	celD	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calycin_like,CelD_N,DUF1080,Glyco_hydro_9,PCMD
SRR25158380_k127_2366341_4	234267.Acid_7572	6.891e-22	99.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_2366341_1	234267.Acid_4612	1.638e-180	578.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158380_k127_2366341_2	1379698.RBG1_1C00001G0607	5.625e-101	350.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158380_k127_2366341_3	1248916.ANFY01000003_gene787	3.373e-32	128.0	COG0346@1|root,COG0346@2|Bacteria,1RK3P@1224|Proteobacteria,2UANZ@28211|Alphaproteobacteria,2K5JM@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_237084_7	234267.Acid_5921	4.626e-05	46.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158380_k127_237084_3	234267.Acid_5921	6.821e-54	198.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158380_k127_237084_1	204669.Acid345_1052	2.169e-170	567.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_237084_2	234267.Acid_1209	3.717e-62	219.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_237084_0	1095769.CAHF01000022_gene253	2.201e-195	635.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_237084_5	931627.MycrhDRAFT_0362	3.287e-10	68.0	COG1917@1|root,COG1917@2|Bacteria,2IRV4@201174|Actinobacteria,23ATB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_237084_4	153721.MYP_4658	5.268e-20	93.0	COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,47M96@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158380_k127_237084_6	588581.Cpap_4155	2.946e-09	59.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia	186801|Clostridia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158380_k127_2372421_0	234267.Acid_7167	3.374e-301	941.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRR25158380_k127_2391112_2	240015.ACP_2463	9.268e-31	133.0	COG1266@1|root,COG1266@2|Bacteria,3Y4ED@57723|Acidobacteria,2JJ3Q@204432|Acidobacteriia	204432|Acidobacteriia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158380_k127_2391112_0	234267.Acid_5135	1.214e-48	180.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Z3@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2391112_1	1267535.KB906767_gene3332	1.481e-40	156.0	2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria,2JJU7@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
SRR25158380_k127_2392841_0	264462.Bd0197	9.128e-105	357.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2MSVH@213481|Bdellovibrionales,2WJI6@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158380_k127_2392841_1	1382359.JIAL01000001_gene1085	6.765e-19	101.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_2397586_0	765869.BDW_10760	0.0	1325.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRR25158380_k127_2398151_4	452637.Oter_3517	3.123e-47	181.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158380_k127_2398151_3	574087.Acear_1028	1.663e-65	237.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WA8M@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_2398151_6	228410.NE0973	1.134e-07	61.0	2AMKC@1|root,3489H@2|Bacteria,1P1IJ@1224|Proteobacteria,2W4A1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2398151_2	1210884.HG799469_gene14163	5.162e-134	440.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158380_k127_2398151_0	1267535.KB906767_gene2100	1.37e-213	689.0	COG0577@1|root,COG0577@2|Bacteria,3Y6QF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_2398151_1	1267534.KB906760_gene1422	1.82e-158	541.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	1267534.KB906760_gene1422|-	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2398151_5	397290.C810_00514	2.265e-11	74.0	COG1943@1|root,COG1943@2|Bacteria,1V28M@1239|Firmicutes,24G86@186801|Clostridia,27TKN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158380_k127_2410180_0	234267.Acid_0837	1.817e-118	381.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3Y47M@57723|Acidobacteria	57723|Acidobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158380_k127_2410180_1	1231391.AMZF01000009_gene1759	1.184e-96	326.0	COG0437@1|root,COG0437@2|Bacteria,1QUMM@1224|Proteobacteria,2WHXZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11
SRR25158380_k127_2410180_2	608538.HTH_0931	4.717e-44	169.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	fdoI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K00127,ko:K08350	ko00630,ko00680,ko01100,ko01120,ko01200,ko02020,map00630,map00680,map01100,map01120,map01200,map02020	-	R00519	RC02796	ko00000,ko00001	5.A.3.2	-	iEC042_1314.EC042_1608,iECED1_1282.ECED1_1627,iECNA114_1301.ECNA114_3649,iECSF_1327.ECSF_1390,iECUMN_1333.ECUMN_1730,ic_1306.c1907	Ni_hydr_CYTB
SRR25158380_k127_2410180_3	443598.AUFA01000010_gene356	1.497e-07	63.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	acfD	-	-	ko:K02004,ko:K10939,ko:K12257,ko:K14393	ko02024,ko03060,ko03070,ko05111,map02024,map03060,map03070,map05111	M00258,M00335	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.21.7,2.A.6.4,3.A.1	-	-	DUF4092,FtsX,M60-like_N,MacB_PCD,Peptidase_M60
SRR25158380_k127_2414974_0	204669.Acid345_2716	2.028e-139	480.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_2414974_1	234267.Acid_4272	9.147e-59	212.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_2424968_3	765420.OSCT_0165	4.866e-19	91.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi,3751G@32061|Chloroflexia	32061|Chloroflexia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158380_k127_2424968_0	1382359.JIAL01000001_gene526	1.238e-104	351.0	COG0416@1|root,COG0416@2|Bacteria,3Y3MM@57723|Acidobacteria,2JHTJ@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158380_k127_2424968_2	1382359.JIAL01000001_gene525	5.543e-21	93.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JJZ9@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158380_k127_2424968_1	667014.Thein_1723	1.293e-27	118.0	COG1399@1|root,COG1399@2|Bacteria,2GHV8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158380_k127_2430442_2	1033802.SSPSH_003546	0.0001641	52.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158380_k127_2430442_0	330214.NIDE3318	1.831e-44	179.0	COG1293@1|root,COG1293@2|Bacteria	2|Bacteria	K	actin binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SRR25158380_k127_2435232_0	244581.IM40_07540	8.555e-82	297.0	COG3515@1|root,COG3523@1|root,COG3515@2|Bacteria,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2TSY0@28211|Alphaproteobacteria,47F0D@766|Rickettsiales	766|Rickettsiales	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
SRR25158380_k127_2440220_5	404380.Gbem_3775	2.261e-27	117.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158380_k127_2440220_1	204669.Acid345_0023	1.087e-86	297.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia	57723|Acidobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158380_k127_2440220_4	1340493.JNIF01000003_gene2554	3.49e-32	131.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158380_k127_2440220_2	697303.Thewi_1007	3.057e-40	157.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,42EM4@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158380_k127_2440220_0	234267.Acid_3160	5.28e-127	414.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR25158380_k127_2440220_3	670487.Ocepr_0539	3.084e-34	132.0	COG0211@1|root,COG0211@2|Bacteria,1WKBG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158380_k127_2440220_6	1379270.AUXF01000006_gene193	2.207e-21	96.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158380_k127_2454316_4	700598.Niako_5211	1.497e-15	77.0	COG0705@1|root,COG0705@2|Bacteria,4NJG9@976|Bacteroidetes,1J16X@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158380_k127_2454316_3	82654.Pse7367_0065	4.15e-34	135.0	COG0780@1|root,COG0780@2|Bacteria,1G5W6@1117|Cyanobacteria,1HB47@1150|Oscillatoriales	1117|Cyanobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158380_k127_2454316_1	443143.GM18_3470	7.831e-111	372.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,43C55@68525|delta/epsilon subdivisions,2X7FI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_2454316_5	661478.OP10G_2756	2.955e-11	70.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158380_k127_2454316_6	5507.FOXG_03045P0	7.287e-05	49.0	2EMXX@1|root,2SRGT@2759|Eukaryota,3A7B1@33154|Opisthokonta,3P5AS@4751|Fungi,3QXM4@4890|Ascomycota,21BKY@147550|Sordariomycetes,3TJ66@5125|Hypocreales,1FVBP@110618|Nectriaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2454316_0	42256.RradSPS_0202	5.084e-140	465.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
SRR25158380_k127_2454316_2	886293.Sinac_0988	1.449e-41	156.0	COG0531@1|root,COG0531@2|Bacteria,2IX7G@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_2466223_3	1131730.BAVI_01460	6.075e-55	195.0	COG4585@1|root,COG4585@2|Bacteria,1UNJA@1239|Firmicutes,4IUGA@91061|Bacilli,1ZSG5@1386|Bacillus	91061|Bacilli	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9
SRR25158380_k127_2466223_2	1232410.KI421428_gene1054	1.349e-141	463.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_2466223_1	204669.Acid345_2712	3.479e-167	540.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SRR25158380_k127_2466223_0	204669.Acid345_2713	4.01e-172	563.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
SRR25158380_k127_2466223_5	204669.Acid345_3829	0.0001975	48.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2466223_4	502025.Hoch_2720	5.271e-17	90.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria	1224|Proteobacteria	C	12 heme-binding sites	cbcC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SRR25158380_k127_246656_1	1382359.JIAL01000001_gene1619	2.048e-69	261.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
SRR25158380_k127_246656_2	204669.Acid345_2692	2.104e-24	117.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_246656_3	926569.ANT_30040	2.832e-20	98.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158380_k127_246656_0	234267.Acid_5495	3.199e-158	505.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	1.13.12.3	ko:K00466	ko00380,map00380	-	R00679	RC00213	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158380_k127_2467989_1	861299.J421_0531	1.115e-175	561.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
SRR25158380_k127_2467989_3	1267535.KB906767_gene4818	1.527e-46	170.0	COG3801@1|root,COG3801@2|Bacteria,3Y89M@57723|Acidobacteria	57723|Acidobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158380_k127_2467989_4	1172188.KB911820_gene2546	1.841e-31	127.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria,4FH0K@85021|Intrasporangiaceae	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158380_k127_2467989_2	378806.STAUR_7860	1.01e-58	208.0	COG1670@1|root,COG1670@2|Bacteria,1N18Y@1224|Proteobacteria,435YY@68525|delta/epsilon subdivisions,2X0G7@28221|Deltaproteobacteria,2Z0UB@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158380_k127_2467989_5	118168.MC7420_2534	1.139e-14	77.0	COG3668@1|root,COG3668@2|Bacteria,1G7UC@1117|Cyanobacteria,1HDRH@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158380_k127_2467989_6	927677.ALVU02000001_gene2054	1.519e-07	55.0	2EA6P@1|root,334BF@2|Bacteria,1G9KH@1117|Cyanobacteria	1117|Cyanobacteria	S	addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158380_k127_2467989_0	1313301.AUGC01000011_gene1125	4.261e-309	959.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRR25158380_k127_247029_1	518766.Rmar_0089	1.688e-73	253.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_247029_2	1254432.SCE1572_13735	1.005e-35	143.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.180	ko:K18846	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_247029_0	1382359.JIAL01000001_gene1531	0.0	1449.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158380_k127_2478385_2	1380347.JNII01000009_gene2271	2.322e-80	273.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EVFA@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_2478385_4	208439.AJAP_17940	8.37e-63	231.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DYCS@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158380_k127_2478385_5	1042375.AFPL01000019_gene269	1.201e-26	119.0	COG4886@1|root,COG4886@2|Bacteria,1NBPC@1224|Proteobacteria,1SRN3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2478385_0	706587.Desti_1032	0.0	1524.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_2478385_1	706587.Desti_1031	1.156e-116	389.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	HlyD_D23
SRR25158380_k127_2478385_3	1121015.N789_09575	2.644e-66	236.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1X6Z0@135614|Xanthomonadales	135614|Xanthomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158380_k127_248011_0	1123250.KB908388_gene205	2.77e-107	362.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158380_k127_248011_1	269799.Gmet_2671	1.127e-65	233.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158380_k127_248011_2	443143.GM18_0200	3.529e-06	51.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,43U9D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158380_k127_2482218_1	234267.Acid_5396	1.608e-113	379.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_2482218_4	1340493.JNIF01000003_gene4236	2.354e-49	183.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158380_k127_2482218_2	635013.TherJR_1583	3.038e-101	345.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
SRR25158380_k127_2482218_8	1047013.AQSP01000090_gene672	4.755e-13	76.0	2DF8J@1|root,2ZQXQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2482218_7	204669.Acid345_1886	2.424e-19	91.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CD225,DUF4339,zinc_ribbon_2
SRR25158380_k127_2482218_5	272134.KB731324_gene3671	2.55e-29	122.0	COG2314@1|root,COG2314@2|Bacteria,1G9J3@1117|Cyanobacteria,1HDPD@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
SRR25158380_k127_2482218_6	1148.1001250	2.042e-23	104.0	2E37T@1|root,32Y7G@2|Bacteria,1GECJ@1117|Cyanobacteria,1H68C@1142|Synechocystis	1117|Cyanobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158380_k127_2482218_0	1278073.MYSTI_02808	5.483e-135	437.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SRR25158380_k127_2482218_3	517418.Ctha_2714	1.624e-49	183.0	COG0500@1|root,COG2226@2|Bacteria,1FFN6@1090|Chlorobi	1090|Chlorobi	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_2483303_1	1128421.JAGA01000002_gene1359	1.216e-76	270.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158380_k127_2483303_0	1120971.AUCA01000011_gene2996	4.786e-88	302.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,27A7C@186823|Alicyclobacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158380_k127_2483303_2	1267535.KB906767_gene2260	2.131e-19	95.0	COG3584@1|root,COG3584@2|Bacteria,3Y8W5@57723|Acidobacteria	57723|Acidobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
SRR25158380_k127_2483303_3	69014.TK0190	2.917e-18	86.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,242WF@183968|Thermococci	183968|Thermococci	F	Catalyzes the synthesis of GMP from XMP	guaAA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR25158380_k127_2487019_3	518766.Rmar_1861	1.654e-34	137.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1FIPJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158380_k127_2487019_1	1122604.JONR01000033_gene34	1.674e-67	238.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158380_k127_2487019_4	195105.CN97_17860	4.023e-05	50.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_2487019_0	479434.Sthe_0801	1.22e-109	364.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158380_k127_2487019_2	204669.Acid345_3565	1.465e-48	188.0	COG3209@1|root,COG3209@2|Bacteria,3Y996@57723|Acidobacteria	57723|Acidobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2496166_2	1123322.KB904680_gene3404	2.116e-53	207.0	COG1232@1|root,COG1232@2|Bacteria,2IEDS@201174|Actinobacteria	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158380_k127_2496166_1	1192034.CAP_7045	5.118e-57	228.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2496166_0	234267.Acid_7677	7.836e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_2504668_2	204669.Acid345_3835	4.649e-17	83.0	COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria,2JMCG@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_2504668_1	216594.MMAR_0242	9.899e-57	210.0	COG0657@1|root,COG0823@1|root,COG0657@2|Bacteria,COG0823@2|Bacteria,2I40M@201174|Actinobacteria,233DD@1762|Mycobacteriaceae	201174|Actinobacteria	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE
SRR25158380_k127_2504668_0	635013.TherJR_2165	1.845e-93	317.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_2511448_2	886293.Sinac_4730	7.91e-215	677.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158380_k127_2511448_0	247490.KSU1_C1626	1.233e-218	694.0	COG1966@1|root,COG1966@2|Bacteria,2IWZE@203682|Planctomycetes	203682|Planctomycetes	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158380_k127_2511448_1	575540.Isop_3575	2.917e-218	692.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_2511448_3	247490.KSU1_C0334	5.663e-18	95.0	COG0589@1|root,COG0589@2|Bacteria,2J042@203682|Planctomycetes	203682|Planctomycetes	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_2511448_5	797210.Halxa_2485	4.811e-09	67.0	COG0589@1|root,arCOG02053@2157|Archaea,2XXES@28890|Euryarchaeota,23VXC@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_2511448_6	240015.ACP_3453	0.0004362	43.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
SRR25158380_k127_2511448_4	1303518.CCALI_01625	5.195e-11	67.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	M1-798	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,Rhodanese
SRR25158380_k127_2521757_2	1283300.ATXB01000001_gene2358	4.536e-73	252.0	COG0500@1|root,COG2226@2|Bacteria,1N5PJ@1224|Proteobacteria,1SBD4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_2521757_3	1132855.KB913035_gene1519	2.581e-39	151.0	COG3544@1|root,COG3544@2|Bacteria,1NC45@1224|Proteobacteria,2WBIE@28216|Betaproteobacteria,2KNTA@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158380_k127_2521757_4	1122921.KB898210_gene2775	3.775e-38	161.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,26TS3@186822|Paenibacillaceae	91061|Bacilli	P	CopC domain	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,YtkA
SRR25158380_k127_2521757_0	1340493.JNIF01000004_gene458	2.766e-170	547.0	COG2132@1|root,COG2132@2|Bacteria,3Y5PP@57723|Acidobacteria	57723|Acidobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_2521757_1	1340493.JNIF01000004_gene459	4.103e-96	336.0	COG1538@1|root,COG1538@2|Bacteria,3Y6KZ@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158380_k127_2523018_2	616991.JPOO01000003_gene1719	4.18e-19	90.0	297MQ@1|root,2ZUUM@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_2523018_6	118168.MC7420_42	0.0002321	53.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria	1117|Cyanobacteria	U	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
SRR25158380_k127_2523018_0	324602.Caur_2455	4.822e-107	351.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158380_k127_2523018_1	760192.Halhy_5240	2.888e-36	150.0	2CSRV@1|root,32SRR@2|Bacteria,4NTI6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NlpE
SRR25158380_k127_2523018_3	321327.CYA_0802	1.058e-13	75.0	COG1219@1|root,COG1219@2|Bacteria,1G04H@1117|Cyanobacteria,1GYBM@1129|Synechococcus	1117|Cyanobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158380_k127_2523018_5	1713.JOFV01000005_gene2318	3.926e-05	48.0	COG1247@1|root,COG1247@2|Bacteria,2GR9D@201174|Actinobacteria,4F1DH@85016|Cellulomonadaceae	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_2532687_0	321327.CYA_2752	2.852e-170	549.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1H46Q@1129|Synechococcus	1117|Cyanobacteria	G	phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158380_k127_2532687_1	1254432.SCE1572_23655	1.839e-52	208.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2532687_3	234267.Acid_5978	2.874e-15	86.0	2EU62@1|root,33MNN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
SRR25158380_k127_2532687_2	179408.Osc7112_2922	4.933e-52	208.0	COG0457@1|root,COG4886@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4886@2|Bacteria,COG4995@2|Bacteria,1G4SR@1117|Cyanobacteria,1HAQW@1150|Oscillatoriales	1117|Cyanobacteria	G	Leucine-rich repeat	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	LRR_4,LRR_6,LRR_8
SRR25158380_k127_2537909_1	314230.DSM3645_20627	2.391e-110	374.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158380_k127_2537909_2	1434929.X946_1372	7.493e-51	183.0	COG3631@1|root,COG3631@2|Bacteria,1N05P@1224|Proteobacteria,2W3M0@28216|Betaproteobacteria,1K8JR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158380_k127_2537909_3	760192.Halhy_4054	7.542e-48	179.0	COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1IS3J@117747|Sphingobacteriia	976|Bacteroidetes	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
SRR25158380_k127_2537909_4	1123393.KB891316_gene2013	1.554e-39	148.0	COG0025@1|root,COG0025@2|Bacteria,1QTZ5@1224|Proteobacteria,2WGIC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158380_k127_2537909_0	1131812.JQMS01000001_gene412	2.104e-158	507.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
SRR25158380_k127_2538127_2	1232410.KI421422_gene2083	1.926e-27	117.0	2DMJE@1|root,32RYR@2|Bacteria,1N7PS@1224|Proteobacteria,42V1W@68525|delta/epsilon subdivisions,2WRWN@28221|Deltaproteobacteria,43UUQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SRR25158380_k127_2538127_1	1144275.COCOR_06229	6.908e-42	174.0	COG0308@1|root,COG0308@2|Bacteria,1P5AT@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158380_k127_2538127_0	1278073.MYSTI_05126	7.96e-50	184.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
SRR25158380_k127_2548712_0	1380394.JADL01000014_gene249	3.222e-99	330.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria,2U09J@28211|Alphaproteobacteria,2JRXS@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_2548712_3	886293.Sinac_0962	7.723e-48	176.0	2CYEB@1|root,32T42@2|Bacteria,2J0FP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2548712_2	240292.Ava_C0142	1.019e-51	190.0	COG1651@1|root,COG1651@2|Bacteria,1G2ZB@1117|Cyanobacteria,1HP1D@1161|Nostocales	1117|Cyanobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_2548712_1	709797.CSIRO_1353	6.264e-54	192.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,3JSR6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_2549671_1	204669.Acid345_1475	7.763e-117	389.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158380_k127_2549671_0	204669.Acid345_1474	6.328e-167	535.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_2551575_4	234267.Acid_7677	6.395e-63	222.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_2551575_1	204669.Acid345_2716	1.743e-167	563.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_2551575_3	1047013.AQSP01000134_gene1354	3.969e-81	272.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_2551575_0	1047013.AQSP01000134_gene1354	1.338e-200	636.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_2551575_2	1267535.KB906767_gene1445	1.574e-108	355.0	2CDZB@1|root,2ZBFS@2|Bacteria,3Y5HH@57723|Acidobacteria,2JM8W@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2551575_5	234267.Acid_2317	1.795e-53	192.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158380_k127_2555253_0	1408473.JHXO01000008_gene2709	6.837e-264	826.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,2FPM1@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	bga	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_2555253_1	234267.Acid_3492	7.594e-81	289.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WQ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_2556091_0	1267534.KB906757_gene1007	1.026e-233	741.0	2C0ZI@1|root,2ZAKK@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
SRR25158380_k127_2556091_1	1267534.KB906757_gene1007	4.516e-48	187.0	2C0ZI@1|root,2ZAKK@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
SRR25158380_k127_2561152_1	251221.35211983	3.621e-170	554.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2561152_0	251221.35211765	3.913e-233	748.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2561152_2	234267.Acid_3786	6.066e-156	507.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_2565074_3	1382359.JIAL01000001_gene2693	2.08e-10	63.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
SRR25158380_k127_2565074_1	56780.SYN_00526	1.114e-36	149.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2MRTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
SRR25158380_k127_2565074_0	765911.Thivi_4010	2.683e-73	258.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales	135613|Chromatiales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158380_k127_2565074_2	1056820.KB900631_gene2330	1.221e-14	76.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,2PNXY@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	Exonuclease VII small subunit	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158380_k127_2569519_1	1112274.KI911560_gene105	7.006e-39	148.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VUZH@28216|Betaproteobacteria,2KKCA@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_2569519_0	1198114.AciX9_2646	6.67e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2569519_3	1173264.KI913949_gene462	1.365e-12	70.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SpoIIE,TIR_2,WD40
SRR25158380_k127_2569966_0	518766.Rmar_2567	1.611e-169	554.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
SRR25158380_k127_2569966_1	1234664.AMRO01000026_gene1206	2.039e-22	103.0	COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1WEG5@129337|Geobacillus	91061|Bacilli	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158380_k127_2571613_0	1283300.ATXB01000001_gene503	4.053e-107	362.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XDTH@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158380_k127_2571613_1	204669.Acid345_1875	4.057e-49	180.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria,2JJ7J@204432|Acidobacteriia	204432|Acidobacteriia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158380_k127_2571613_2	292459.STH3333	1.416e-24	107.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158380_k127_2574426_5	1245469.S58_67430	1.564e-36	145.0	COG0300@1|root,COG0300@2|Bacteria,1R3VU@1224|Proteobacteria,2TWRJ@28211|Alphaproteobacteria,3K6MX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc,adh_short,adh_short_C2
SRR25158380_k127_2574426_4	234267.Acid_2875	6.539e-107	358.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158380_k127_2574426_6	1173026.Glo7428_1830	1.826e-33	135.0	COG1225@1|root,COG1225@2|Bacteria,1G59X@1117|Cyanobacteria	1117|Cyanobacteria	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_2574426_7	379066.GAU_0167	2.405e-22	99.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR25158380_k127_2574426_8	592316.Pat9b_3330	1.449e-05	54.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,3VZYT@53335|Pantoea	1236|Gammaproteobacteria	S	periplasmic	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158380_k127_2574426_2	861299.J421_0738	1.491e-155	508.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158380_k127_2574426_1	861299.J421_0737	2.796e-183	585.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_2574426_3	861299.J421_0736	4.447e-152	496.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_2574426_0	575540.Isop_3282	0.0	1293.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158380_k127_2574494_2	237368.SCABRO_01358	2.696e-88	296.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158380_k127_2574494_7	1340493.JNIF01000003_gene2485	3.736e-27	123.0	COG1596@1|root,COG1596@2|Bacteria,3Y7QA@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158380_k127_2574494_8	751945.Theos_0891	6.584e-08	62.0	COG2197@1|root,COG2197@2|Bacteria,1WJUW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158380_k127_2574494_5	749222.Nitsa_1425	4.309e-58	209.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,42QUT@68525|delta/epsilon subdivisions,2YNVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158380_k127_2574494_0	234267.Acid_4760	3.125e-258	826.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158380_k127_2574494_4	1123073.KB899242_gene950	9.547e-73	260.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1X53Q@135614|Xanthomonadales	135614|Xanthomonadales	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158380_k127_2574494_6	153721.MYP_2939	2.873e-45	173.0	COG0791@1|root,COG0791@2|Bacteria,4NSRM@976|Bacteroidetes,47RKG@768503|Cytophagia	976|Bacteroidetes	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2574494_3	1123399.AQVE01000011_gene1233	2.015e-75	265.0	2EE8J@1|root,33831@2|Bacteria,1ND96@1224|Proteobacteria,1SED2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2574494_1	1122604.JONR01000018_gene1061	1.747e-101	340.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,1S05Q@1236|Gammaproteobacteria,1X429@135614|Xanthomonadales	135614|Xanthomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158380_k127_2580239_7	292459.STH3180	5.326e-55	201.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158380_k127_2580239_9	861299.J421_2526	1.547e-42	164.0	COG2802@1|root,COG2802@2|Bacteria,1ZUZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158380_k127_2580239_11	1454004.AW11_00348	1.135e-19	94.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	atoC	-	-	ko:K02481,ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_2580239_10	1340493.JNIF01000004_gene1042	2.013e-20	104.0	2DUZM@1|root,33T72@2|Bacteria,3Y7AK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2580239_2	215803.DB30_5846	3.875e-121	399.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2WMVT@28221|Deltaproteobacteria,2YVTT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_2580239_0	246197.MXAN_1010	4.426e-147	479.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,43AI0@68525|delta/epsilon subdivisions,2X5Y7@28221|Deltaproteobacteria,2YURU@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158380_k127_2580239_4	1128421.JAGA01000003_gene3695	2.802e-100	334.0	COG0338@1|root,COG0338@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158380_k127_2580239_8	28072.Nos7524_5414	3.001e-52	200.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HNFR@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158380_k127_2580239_3	1183438.GKIL_2157	9.105e-106	355.0	COG4076@1|root,COG4076@2|Bacteria,1G4RK@1117|Cyanobacteria	1117|Cyanobacteria	J	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PRMT5_C,PrmA
SRR25158380_k127_2580239_5	395961.Cyan7425_1025	7.506e-70	249.0	COG1493@1|root,COG1493@2|Bacteria,1G5K9@1117|Cyanobacteria	1117|Cyanobacteria	T	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2580239_1	395961.Cyan7425_1026	3.485e-123	417.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria	1117|Cyanobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158380_k127_2580239_6	1384054.N790_08115	1.339e-62	238.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XCG4@135614|Xanthomonadales	135614|Xanthomonadales	D	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
SRR25158380_k127_2583478_2	204669.Acid345_0050	1.2e-90	305.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158380_k127_2583478_3	1382359.JIAL01000001_gene2600	1.266e-10	72.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158380_k127_2583478_1	986075.CathTA2_2774	6.825e-120	394.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_2583478_0	1051632.TPY_0985	8.911e-132	429.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_2599761_3	290400.Jann_4112	5.437e-21	105.0	COG0673@1|root,COG0673@2|Bacteria,1PTXT@1224|Proteobacteria,2TVNJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_2599761_2	56110.Oscil6304_0203	5.673e-41	171.0	COG3379@1|root,COG3379@2|Bacteria,1G1KP@1117|Cyanobacteria,1H87X@1150|Oscillatoriales	1117|Cyanobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158380_k127_2599761_4	1128421.JAGA01000002_gene1863	6.548e-14	75.0	2EFVT@1|root,339N0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
SRR25158380_k127_2599761_0	929713.NIASO_15630	3.477e-219	693.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1IQY0@117747|Sphingobacteriia	976|Bacteroidetes	P	sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158380_k127_2599761_1	1033806.HTIA_1260	2.421e-79	274.0	COG3568@1|root,arCOG08107@2157|Archaea,2XWUM@28890|Euryarchaeota,23VI9@183963|Halobacteria	183963|Halobacteria	L	COG3568 Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158380_k127_2604345_5	358681.BBR47_42160	3.206e-17	83.0	arCOG11411@1|root,33A8Q@2|Bacteria,1VM7Z@1239|Firmicutes,4HR18@91061|Bacilli,2744P@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2604345_3	323261.Noc_1872	2.392e-55	195.0	arCOG11412@1|root,31S84@2|Bacteria,1N14M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2604345_2	1487953.JMKF01000079_gene4161	7.312e-57	201.0	2DB76@1|root,2Z7JZ@2|Bacteria,1GRAE@1117|Cyanobacteria,1HIB6@1150|Oscillatoriales	1117|Cyanobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR25158380_k127_2604345_0	247490.KSU1_B0598	1.366e-144	469.0	COG3497@1|root,COG3497@2|Bacteria,2IXRX@203682|Planctomycetes	203682|Planctomycetes	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158380_k127_2604345_1	1449346.JQMO01000003_gene2879	8.804e-63	226.0	2DME4@1|root,32QWA@2|Bacteria,2GVI0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SRR25158380_k127_2604345_4	1120949.KB903317_gene1760	1.504e-36	145.0	COG1361@1|root,COG1361@2|Bacteria,2I6N1@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158380_k127_2606150_5	204669.Acid345_0248	9.695e-27	119.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158380_k127_2606150_0	234267.Acid_1040	6.088e-195	627.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria	57723|Acidobacteria	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
SRR25158380_k127_2606150_2	706587.Desti_1219	1.57e-34	136.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2MS63@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158380_k127_2606150_3	1249997.JHZW01000002_gene589	3.678e-34	136.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1I2SM@117743|Flavobacteriia,2PIMZ@252356|Maribacter	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_2606150_1	1125863.JAFN01000001_gene1446	1.03e-118	398.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_2606150_6	404589.Anae109_0620	2.959e-05	55.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42RPW@68525|delta/epsilon subdivisions,2WK10@28221|Deltaproteobacteria,2Z2WV@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_2
SRR25158380_k127_2606150_4	861299.J421_2716	1.483e-29	121.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2614484_9	861299.J421_5594	4.984e-50	181.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_2614484_13	1286632.P278_05280	4.519e-05	48.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,1HYDS@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158380_k127_2614484_4	9031.ENSGALP00000014204	5.78e-89	299.0	COG3340@1|root,2QR7X@2759|Eukaryota,39DGA@33154|Opisthokonta,3BC18@33208|Metazoa,3CWYN@33213|Bilateria,484TW@7711|Chordata,499CC@7742|Vertebrata,4GIAY@8782|Aves	33208|Metazoa	E	Peptidase family S51	-	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158380_k127_2614484_1	1173023.KE650771_gene4438	1.942e-128	423.0	COG0465@1|root,COG0465@2|Bacteria,1G46Q@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158380_k127_2614484_2	234267.Acid_3338	1.029e-116	383.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20,Hydrolase_3,S6PP
SRR25158380_k127_2614484_7	187303.BN69_1124	1.474e-79	276.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119,2.7.1.163	ko:K17880,ko:K18817	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
SRR25158380_k127_2614484_11	472759.Nhal_3072	1.058e-22	110.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria	1224|Proteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158380_k127_2614484_5	518766.Rmar_1244	2.174e-85	302.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1FIST@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158380_k127_2614484_10	563040.Saut_0659	2.595e-35	140.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2YPZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158380_k127_2614484_0	1303518.CCALI_00492	1.151e-213	684.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158380_k127_2614484_12	391038.Bphy_1847	1.688e-11	68.0	COG4319@1|root,COG4319@2|Bacteria,1RII1@1224|Proteobacteria,2VXCZ@28216|Betaproteobacteria,1K8QB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_2614484_8	926566.Terro_0813	3.118e-74	259.0	COG1295@1|root,COG1295@2|Bacteria,3Y3RZ@57723|Acidobacteria,2JIYV@204432|Acidobacteriia	204432|Acidobacteriia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158380_k127_2614484_6	181119.XP_005526451.1	1.426e-83	285.0	COG0434@1|root,2QUBS@2759|Eukaryota,38EZC@33154|Opisthokonta,3BES3@33208|Metazoa,3D0S4@33213|Bilateria,47ZQG@7711|Chordata,4905V@7742|Vertebrata,4GQ2R@8782|Aves	33208|Metazoa	S	protein F13E9.13, mitochondrial-like	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
SRR25158380_k127_2614484_3	861299.J421_3004	4.431e-102	337.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_2617395_3	234267.Acid_1335	1.151e-27	115.0	COG2315@1|root,COG2315@2|Bacteria,3Y5I0@57723|Acidobacteria	57723|Acidobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158380_k127_2617395_0	1254432.SCE1572_13105	4.715e-115	386.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,42PIM@68525|delta/epsilon subdivisions,2WKI0@28221|Deltaproteobacteria,2Z1SA@29|Myxococcales	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2617395_2	682795.AciX8_0041	2.749e-44	168.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_2617395_1	661478.OP10G_3245	1.272e-44	166.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_2617395_4	502025.Hoch_2463	4.931e-12	67.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,42TIX@68525|delta/epsilon subdivisions,2WP2M@28221|Deltaproteobacteria,2Z1YB@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158380_k127_2622051_1	767817.Desgi_0475	1.124e-49	184.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,262AM@186807|Peptococcaceae	186801|Clostridia	I	PFAM Enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_2622051_3	1127695.HMPREF9163_00471	7.737e-21	96.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158380_k127_2622051_0	1123261.AXDW01000004_gene2796	5.938e-104	354.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,1S3FZ@1236|Gammaproteobacteria,1X54C@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_2622051_2	234267.Acid_1153	8.787e-43	160.0	COG0774@1|root,COG0774@2|Bacteria,3Y40I@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
SRR25158380_k127_2622445_6	1123242.JH636434_gene4698	9.319e-33	131.0	COG1028@1|root,COG1028@2|Bacteria,2IZBD@203682|Planctomycetes	203682|Planctomycetes	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_2622445_5	198214.SF3978	4.841e-36	140.0	COG3254@1|root,COG3254@2|Bacteria,1RGYV@1224|Proteobacteria,1S6AI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Involved in the anomeric conversion of L-rhamnose	rhaM	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
SRR25158380_k127_2622445_4	390989.JOEG01000006_gene734	5.799e-66	235.0	COG0491@1|root,COG0491@2|Bacteria,2GMPG@201174|Actinobacteria,4DIDN@85008|Micromonosporales	201174|Actinobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2622445_2	471854.Dfer_3040	2.265e-102	340.0	COG1028@1|root,COG1028@2|Bacteria,4NGYN@976|Bacteroidetes,47NHS@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_2622445_1	159749.K0RDA3	9.489e-177	562.0	COG4948@1|root,2QRKX@2759|Eukaryota,2XFGI@2836|Bacillariophyta	2836|Bacillariophyta	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158380_k127_2622445_0	1173028.ANKO01000147_gene1308	3.186e-185	591.0	COG0076@1|root,COG0076@2|Bacteria,1G3F8@1117|Cyanobacteria,1H9S6@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86	ko:K01580,ko:K01593,ko:K13745	ko00250,ko00260,ko00350,ko00360,ko00380,ko00410,ko00430,ko00650,ko00901,ko00950,ko00965,ko01100,ko01110,ko01120,ko02024,ko04726,ko04727,ko04728,ko04940,ko05030,ko05031,ko05034,map00250,map00260,map00350,map00360,map00380,map00410,map00430,map00650,map00901,map00950,map00965,map01100,map01110,map01120,map02024,map04726,map04727,map04728,map04940,map05030,map05031,map05034	M00027,M00037,M00042	R00261,R00489,R00685,R00699,R00736,R01682,R02080,R02466,R02701,R04909,R07650	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158380_k127_2622445_8	926550.CLDAP_22580	4.404e-24	105.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR25158380_k127_2622445_3	3218.PP1S46_300V6.1	1.851e-99	336.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_2622445_7	1297742.A176_06361	1.374e-31	126.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,4315K@68525|delta/epsilon subdivisions,2WWYY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158380_k127_2631538_1	1123023.JIAI01000009_gene1233	1.235e-64	231.0	COG0501@1|root,COG0501@2|Bacteria,2HV37@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2631538_2	134676.ACPL_390	1.648e-29	127.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158380_k127_2631538_0	1267534.KB906760_gene1549	3.948e-75	261.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158380_k127_2642026_2	167555.NATL1_19711	2.09e-16	92.0	COG0457@1|root,COG2227@1|root,COG0457@2|Bacteria,COG2227@2|Bacteria,1GMZ8@1117|Cyanobacteria,1MNHZ@1212|Prochloraceae	1117|Cyanobacteria	H	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31,TPR_1,TPR_8
SRR25158380_k127_2642026_1	448385.sce2235	8.924e-58	226.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce2235|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2642026_0	1267533.KB906733_gene3259	7.553e-122	402.0	COG0495@1|root,COG0495@2|Bacteria,3Y37K@57723|Acidobacteria,2JIGF@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_2644823_1	795666.MW7_0306	5.949e-84	313.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
SRR25158380_k127_2644823_0	926566.Terro_0850	2.053e-289	905.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158380_k127_2644823_3	1267534.KB906759_gene1948	6.201e-59	208.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	coxS	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158380_k127_2644823_2	1267534.KB906759_gene1949	4.947e-78	270.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158380_k127_2653466_2	682795.AciX8_2456	8.497e-46	168.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3JK@57723|Acidobacteria,2JIZX@204432|Acidobacteriia	204432|Acidobacteriia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
SRR25158380_k127_2653466_3	497964.CfE428DRAFT_4487	1.122e-30	125.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158380_k127_2653466_0	1156937.MFUM_970015	3.916e-230	719.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,37FV6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158380_k127_2653466_1	497964.CfE428DRAFT_4490	1.611e-74	259.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158380_k127_2655659_0	1382359.JIAL01000001_gene74	3.801e-236	773.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C
SRR25158380_k127_2655659_1	700598.Niako_5370	4.828e-225	714.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IREG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
SRR25158380_k127_2655659_2	1185876.BN8_00463	2.426e-103	353.0	2DB8U@1|root,2Z7SW@2|Bacteria,4NEUK@976|Bacteroidetes,47KH1@768503|Cytophagia	976|Bacteroidetes	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
SRR25158380_k127_265572_1	373994.Riv7116_4310	1.463e-122	398.0	COG1028@1|root,COG1028@2|Bacteria,1GD92@1117|Cyanobacteria,1HQFS@1161|Nostocales	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_265572_0	373994.Riv7116_4309	2.1e-161	514.0	COG0809@1|root,COG0809@2|Bacteria,1G02D@1117|Cyanobacteria,1HJ1X@1161|Nostocales	2|Bacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158380_k127_265572_3	338966.Ppro_0311	1.592e-22	100.0	COG1359@1|root,COG1359@2|Bacteria,1PVN9@1224|Proteobacteria,43EXN@68525|delta/epsilon subdivisions,2X2HQ@28221|Deltaproteobacteria,43VHE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158380_k127_265572_2	177439.DP2251	7.892e-51	184.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2WPDU@28221|Deltaproteobacteria,2MK9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158380_k127_2655813_1	379066.GAU_3509	1.859e-106	350.0	COG1484@1|root,COG1484@2|Bacteria,1ZV5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158380_k127_2655813_0	379066.GAU_3508	2.4e-201	641.0	COG4584@1|root,COG4584@2|Bacteria,1ZV8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158380_k127_2655813_3	391625.PPSIR1_35307	8.018e-31	129.0	COG3209@1|root,COG3209@2|Bacteria,1QZU3@1224|Proteobacteria	1224|Proteobacteria	M	Fungal chitosanase of glycosyl hydrolase group 75	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_75
SRR25158380_k127_2655813_2	926554.KI912637_gene3425	3.296e-55	203.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158380_k127_2655813_5	1248916.ANFY01000004_gene1680	1.459e-25	125.0	COG2931@1|root,COG2931@2|Bacteria,1RD10@1224|Proteobacteria,2U9TE@28211|Alphaproteobacteria,2K1W4@204457|Sphingomonadales	204457|Sphingomonadales	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158380_k127_2655813_4	1128427.KB904821_gene1634	8.402e-26	126.0	COG1404@1|root,COG3121@1|root,COG3291@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3121@2|Bacteria,COG3291@2|Bacteria,COG5549@2|Bacteria,1G2HU@1117|Cyanobacteria,1H9MN@1150|Oscillatoriales	2|Bacteria	O	PFAM Uncharacterised BCR, COG1649	prtB	-	1.1.3.9,3.2.1.4	ko:K01179,ko:K04618,ko:K07346,ko:K12685,ko:K17734	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R01098,R06200,R11307,R11308	RC00194	ko00000,ko00001,ko01000,ko01002,ko02000,ko02035,ko02044,ko03110	1.B.12.5.1,1.B.12.5.3	GH5,GH9	-	Autotransporter,F5_F8_type_C,Peptidase_M57,Peptidase_S8
SRR25158380_k127_2655813_6	439235.Dalk_2163	0.000357	50.0	COG2755@1|root,COG2755@2|Bacteria,1PBR7@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2658631_1	195250.CM001776_gene2434	0.0003512	47.0	COG0589@1|root,COG0589@2|Bacteria,1G6JK@1117|Cyanobacteria,1H1B8@1129|Synechococcus	1117|Cyanobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_2658631_0	1125973.JNLC01000002_gene2004	5.388e-270	866.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3JWMN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRR25158380_k127_2669608_0	530564.Psta_3388	2.715e-85	322.0	COG0457@1|root,COG0457@2|Bacteria,2IZTX@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2670044_3	886293.Sinac_5540	4.44e-12	68.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158380_k127_2670044_0	1382359.JIAL01000001_gene959	2.464e-136	444.0	COG0642@1|root,COG2205@2|Bacteria,3Y33Y@57723|Acidobacteria,2JHWF@204432|Acidobacteriia	204432|Acidobacteriia	T	Osmosensitive K channel His kinase sensor	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
SRR25158380_k127_2670044_2	204669.Acid345_0512	9.453e-73	250.0	COG2156@1|root,COG2156@2|Bacteria,3Y49M@57723|Acidobacteria,2JJ0W@204432|Acidobacteriia	204432|Acidobacteriia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRR25158380_k127_2670044_1	68260.JOAY01000039_gene2248	7.993e-99	325.0	COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158380_k127_2670713_3	234267.Acid_2600	4.005e-51	184.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2670713_5	521674.Plim_3942	3.317e-06	57.0	COG0526@1|root,COG0526@2|Bacteria,2IZKM@203682|Planctomycetes	203682|Planctomycetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
SRR25158380_k127_2670713_2	204669.Acid345_0180	6.141e-54	205.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
SRR25158380_k127_2670713_4	314230.DSM3645_29481	1.058e-19	103.0	COG0526@1|root,COG0526@2|Bacteria,2J35Z@203682|Planctomycetes	203682|Planctomycetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR25158380_k127_2670713_1	1278073.MYSTI_03719	9.134e-78	274.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158380_k127_2670713_0	204669.Acid345_4042	8.498e-111	366.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_2676338_0	518766.Rmar_1660	1.258e-89	300.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1FJ1Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158380_k127_2676338_1	240015.ACP_1467	5.112e-88	301.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria,2JICI@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158380_k127_2676338_2	234267.Acid_6981	3.281e-49	183.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158380_k127_2681446_2	1198114.AciX9_2114	1.191e-43	164.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,3Y3VV@57723|Acidobacteria,2JHRV@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158380_k127_2681446_3	1089550.ATTH01000001_gene1014	9.363e-30	132.0	COG0699@1|root,COG1520@1|root,COG0699@2|Bacteria,COG1520@2|Bacteria,4PHXE@976|Bacteroidetes,1FKAD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2681446_0	204669.Acid345_2359	7.081e-52	195.0	COG1183@1|root,COG1183@2|Bacteria,3Y3I7@57723|Acidobacteria,2JIEG@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158380_k127_2681446_1	1131269.AQVV01000018_gene1893	1.107e-48	181.0	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158380_k127_2681446_7	204669.Acid345_2361	6.023e-07	54.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria,2JNW9@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
SRR25158380_k127_2681446_5	671143.DAMO_1552	1.468e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,2NPTV@2323|unclassified Bacteria	2|Bacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158380_k127_2681446_4	335543.Sfum_1786	2.34e-24	111.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2MQKS@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158380_k127_2681446_6	118168.MC7420_3051	3.329e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_2683203_0	1183438.GKIL_3942	4.055e-40	153.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158380_k127_2691438_1	1396141.BATP01000061_gene4479	7.905e-33	129.0	COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia,2IUAA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158380_k127_2691438_0	246197.MXAN_2289	1.232e-155	506.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158380_k127_2698636_0	1288494.EBAPG3_1360	3.265e-298	927.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158380_k127_2698636_5	485913.Krac_4003	4.107e-24	104.0	2E4G6@1|root,335WF@2|Bacteria,2G9R2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2698636_2	479434.Sthe_0342	3.434e-98	326.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158380_k127_2698636_3	479434.Sthe_0341	1.952e-94	313.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158380_k127_2698636_4	351160.RCIX322	1.514e-62	225.0	COG0428@1|root,arCOG00576@2157|Archaea,2XX28@28890|Euryarchaeota,2NAV5@224756|Methanomicrobia	224756|Methanomicrobia	P	divalent heavy-metal cations transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
SRR25158380_k127_2698636_1	1042326.AZNV01000003_gene3997	5.491e-155	492.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,4B8Q9@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158380_k127_2701754_1	1192034.CAP_5407	5.918e-177	563.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158380_k127_2701754_5	246197.MXAN_5701	8.336e-18	93.0	2EDTI@1|root,337NU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2701754_3	378806.STAUR_6365	2.371e-39	156.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria,438WP@68525|delta/epsilon subdivisions,2X9RW@28221|Deltaproteobacteria,2YY15@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158380_k127_2701754_2	1382359.JIAL01000001_gene899	1.399e-126	418.0	COG0151@1|root,COG0151@2|Bacteria,3Y47C@57723|Acidobacteria,2JIFR@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158380_k127_2701754_4	234267.Acid_4370	2.231e-30	124.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria	57723|Acidobacteria	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158380_k127_2701754_0	56107.Cylst_0650	4.927e-255	802.0	COG0531@1|root,COG0531@2|Bacteria,1G1I6@1117|Cyanobacteria,1HK4Y@1161|Nostocales	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2711765_1	1267534.KB906755_gene4673	4.232e-112	370.0	COG2273@1|root,COG2273@2|Bacteria,3Y6GF@57723|Acidobacteria,2JKH1@204432|Acidobacteriia	204432|Acidobacteriia	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2711765_0	1267534.KB906755_gene4687	0.0	1060.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y6BT@57723|Acidobacteria,2JKYZ@204432|Acidobacteriia	204432|Acidobacteriia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158380_k127_2711765_2	1267534.KB906755_gene4688	8.38e-97	319.0	COG2197@1|root,COG2197@2|Bacteria,3Y4G0@57723|Acidobacteria,2JJ28@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_2711765_3	1124983.PFLCHA0_c34650	1.287e-55	199.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5U@1224|Proteobacteria,1SAZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD,HDOD
SRR25158380_k127_2711765_4	883078.HMPREF9695_04166	1.43e-19	89.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,3JSR6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_2713404_0	1047013.AQSP01000079_gene2039	3.348e-146	473.0	2C57D@1|root,2Z7RS@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SRR25158380_k127_2713404_2	76114.p2A113	4.039e-77	264.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158380_k127_2713404_1	661478.OP10G_0571	3.257e-79	270.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	MA20_42490	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158380_k127_2713404_4	1296416.JACB01000001_gene3358	9.587e-15	85.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia,2YKRI@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_2722271_1	46429.BV95_03428	4.445e-11	66.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3,PD40
SRR25158380_k127_2722271_0	1278073.MYSTI_02055	4.756e-194	634.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_2724926_4	395493.BegalDRAFT_1852	1.298e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,461AF@72273|Thiotrichales	72273|Thiotrichales	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158380_k127_2724926_2	1379698.RBG1_1C00001G1052	3.082e-41	164.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SRR25158380_k127_2724926_3	452637.Oter_1641	2.076e-32	130.0	2CCSR@1|root,32RWC@2|Bacteria,46WYJ@74201|Verrucomicrobia,3K9ZP@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_2724926_0	204669.Acid345_1289	1.739e-158	507.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria,2JKWC@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158380_k127_2724926_1	525146.Ddes_1661	4.313e-94	325.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2M82J@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158380_k127_2726004_2	1254432.SCE1572_13755	7.189e-71	243.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,433XH@68525|delta/epsilon subdivisions,2X2FU@28221|Deltaproteobacteria,2YXR6@29|Myxococcales	28221|Deltaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158380_k127_2726004_1	234267.Acid_4345	5.338e-74	269.0	COG0577@1|root,COG2203@1|root,COG2208@1|root,COG0577@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y6XZ@57723|Acidobacteria	57723|Acidobacteria	KTV	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD,SpoIIE
SRR25158380_k127_2726004_0	251221.35211765	3.719e-185	606.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2732284_3	1382359.JIAL01000001_gene2110	7.863e-13	71.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria,2JJS9@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158380_k127_2732284_0	204669.Acid345_3538	9.2e-116	380.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria,2JI4V@204432|Acidobacteriia	204432|Acidobacteriia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158380_k127_2732284_2	1267533.KB906733_gene3065	5.331e-27	115.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia	204432|Acidobacteriia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158380_k127_2732284_1	1047013.AQSP01000057_gene1926	8.018e-65	238.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158380_k127_2732284_4	1461577.CCMH01000005_gene1888	3.205e-06	51.0	2EF83@1|root,33912@2|Bacteria,4NWNU@976|Bacteroidetes,1IID6@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
SRR25158380_k127_2735646_1	525897.Dbac_1184	1.944e-124	404.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158380_k127_2735646_0	234267.Acid_5526	1.528e-235	740.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158380_k127_2735646_5	370438.PTH_0425	2.218e-06	51.0	arCOG06390@1|root,330IR@2|Bacteria,1VCE0@1239|Firmicutes,25D9K@186801|Clostridia,2636K@186807|Peptococcaceae	186801|Clostridia	S	Gas vesicle protein K	-	-	-	-	-	-	-	-	-	-	-	-	GvpK
SRR25158380_k127_2735646_4	203124.Tery_2324	7.408e-08	57.0	arCOG03092@1|root,32YMQ@2|Bacteria,1G7U9@1117|Cyanobacteria,1HCCG@1150|Oscillatoriales	1117|Cyanobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158380_k127_2735646_2	204669.Acid345_2403	1.888e-41	169.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,3Y2RK@57723|Acidobacteria,2JHY1@204432|Acidobacteriia	204432|Acidobacteriia	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS
SRR25158380_k127_2742526_0	1267535.KB906767_gene4961	1.835e-24	110.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158380_k127_2743001_1	1329516.JPST01000003_gene1164	6.021e-84	286.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4HABY@91061|Bacilli,27CM5@186824|Thermoactinomycetaceae	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158380_k127_2743001_0	665952.HMPREF1015_02484	1.933e-170	547.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,1ZAT1@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_2743001_2	1206101.AZXC01000019_gene1471	3.566e-33	134.0	COG2453@1|root,COG2453@2|Bacteria,2IK44@201174|Actinobacteria	201174|Actinobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
SRR25158380_k127_2743001_3	649639.Bcell_0434	2.749e-13	73.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158380_k127_2743638_2	215803.DB30_1717	2.439e-09	61.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158380_k127_2743638_1	1123073.KB899245_gene76	5.899e-115	379.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,1RMNE@1236|Gammaproteobacteria,1X7UX@135614|Xanthomonadales	135614|Xanthomonadales	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158380_k127_2743638_0	1146883.BLASA_1735	5.746e-115	387.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158380_k127_275_1	1550091.JROE01000006_gene2330	5.001e-79	277.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1INXD@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SRR25158380_k127_275_0	1283287.KB822575_gene219	3.438e-213	687.0	COG3387@1|root,COG4945@1|root,COG3387@2|Bacteria,COG4945@2|Bacteria,2HCB8@201174|Actinobacteria	201174|Actinobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	CBM_20,Glucodextran_N,Glyco_hydro_15,fn3
SRR25158380_k127_2750042_4	1502851.FG93_03398	3.596e-58	210.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,FR47,GNAT_acetyltran
SRR25158380_k127_2750042_7	7668.SPU_001946-tr	9.996e-12	70.0	COG0666@1|root,KOG4177@2759|Eukaryota,39NEB@33154|Opisthokonta	2759|Eukaryota	M	ZU5 domain	-	-	1.14.13.225	ko:K15502,ko:K19947	-	-	-	-	ko00000,ko01000,ko01009,ko03400,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
SRR25158380_k127_2750042_5	1713.JOFV01000005_gene2357	2.026e-24	106.0	COG4319@1|root,COG4319@2|Bacteria,2IMG5@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_2750042_1	1267535.KB906767_gene1253	2.511e-103	345.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_2750042_3	485913.Krac_9732	3.836e-62	228.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
SRR25158380_k127_2750042_2	335543.Sfum_3401	4.079e-94	318.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2MR2X@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158380_k127_2750042_0	436308.Nmar_0657	2.209e-142	467.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR25158380_k127_2750042_9	1267534.KB906756_gene325	0.0009656	49.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	204432|Acidobacteriia	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158380_k127_2750042_6	661478.OP10G_4149	6.848e-12	71.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
SRR25158380_k127_2756151_3	1235279.C772_01965	7.026e-27	116.0	COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,26DWR@186818|Planococcaceae	91061|Bacilli	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SRR25158380_k127_2756151_2	1089548.KI783301_gene331	1.58e-32	131.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,3WFI7@539002|Bacillales incertae sedis	91061|Bacilli	P	Belongs to the Fur family	perR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158380_k127_2756151_0	1341151.ASZU01000006_gene2792	1.658e-81	279.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,27B7C@186824|Thermoactinomycetaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158380_k127_2756151_1	1196028.ALEF01000017_gene2463	1.091e-39	153.0	COG0526@1|root,COG0526@2|Bacteria,1V1R4@1239|Firmicutes,4HFWU@91061|Bacilli,4C5T4@84406|Virgibacillus	91061|Bacilli	CO	Thioredoxin-like	ykuV	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_2762618_0	926550.CLDAP_31540	4.879e-149	484.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2762618_2	84531.JMTZ01000038_gene3588	1.019e-38	154.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158380_k127_2762618_1	485916.Dtox_3945	3.141e-40	160.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,2673P@186807|Peptococcaceae	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158380_k127_2762618_3	1045854.WKK_05550	1.43e-26	111.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,4AX50@81850|Leuconostocaceae	91061|Bacilli	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Hydrolase_3,Pro_isomerase
SRR25158380_k127_2772527_1	204669.Acid345_4299	1.273e-104	360.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria,2JHU4@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158380_k127_2772527_2	401526.TcarDRAFT_1767	4.958e-102	355.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4H2CM@909932|Negativicutes	909932|Negativicutes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
SRR25158380_k127_2772527_4	639030.JHVA01000001_gene2730	1.99e-13	74.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158380_k127_2772527_0	1382359.JIAL01000001_gene1505	1.15e-161	521.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158380_k127_2772527_3	1170562.Cal6303_1880	1.281e-73	262.0	COG0337@1|root,COG0337@2|Bacteria,1G03C@1117|Cyanobacteria,1HIJQ@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158380_k127_2793655_0	1340493.JNIF01000003_gene3478	1.321e-176	592.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_2794416_1	1123059.KB823011_gene984	8.408e-101	335.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,43WFY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158380_k127_2794416_3	1267533.KB906733_gene3398	8.218e-09	64.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_2794416_0	1340493.JNIF01000003_gene4071	7.445e-136	445.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158380_k127_2794416_2	646529.Desaci_1821	1.659e-66	236.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158380_k127_2800737_2	1123371.ATXH01000022_gene961	4.482e-26	113.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158380_k127_2800737_0	697281.Mahau_1700	4.888e-105	350.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,42EZE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Phosphate acetyl butaryl transferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
SRR25158380_k127_2800737_3	682795.AciX8_1406	9.601e-07	61.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_2800737_1	204669.Acid345_2498	1.741e-89	309.0	COG3437@1|root,COG3437@2|Bacteria,3Y2TI@57723|Acidobacteria,2JHKC@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
SRR25158380_k127_2806148_0	1121920.AUAU01000016_gene1339	2.783e-162	526.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158380_k127_2806148_4	1340493.JNIF01000003_gene3076	2.313e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,3Y3BD@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_2806148_1	945713.IALB_0290	1.165e-84	287.0	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SRR25158380_k127_2806148_2	330214.NIDE0244	2.49e-76	261.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158380_k127_2806148_3	204669.Acid345_4448	1.677e-28	126.0	COG1595@1|root,COG1595@2|Bacteria,3Y7TB@57723|Acidobacteria,2JMZD@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158380_k127_2809948_0	857087.Metme_1577	1.037e-08	66.0	29V32@1|root,30GGD@2|Bacteria,1REXD@1224|Proteobacteria,1SXAI@1236|Gammaproteobacteria,1XFXV@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2820434_3	925775.XVE_3913	1.54e-12	76.0	COG3206@1|root,COG3206@2|Bacteria,1RK0N@1224|Proteobacteria,1S5G8@1236|Gammaproteobacteria,1X53D@135614|Xanthomonadales	135614|Xanthomonadales	M	protein involved in exopolysaccharide biosynthesis	gumC	-	-	ko:K13661	-	-	-	-	ko00000	-	-	-	GNVR,Wzz
SRR25158380_k127_2820434_1	370438.PTH_1080	1.49e-52	197.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,261FK@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158380_k127_2820434_0	634956.Geoth_0303	5.864e-122	400.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1WHF3@129337|Geobacillus	91061|Bacilli	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158380_k127_2820434_2	1245469.S58_15410	3.062e-52	194.0	2AUD4@1|root,31K11@2|Bacteria,1RI0U@1224|Proteobacteria,2U998@28211|Alphaproteobacteria,3K0BU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158380_k127_2820606_0	1242864.D187_006563	2.801e-80	277.0	COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,42RYU@68525|delta/epsilon subdivisions,2WNVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
SRR25158380_k127_2820606_1	1499967.BAYZ01000105_gene3510	4.428e-78	288.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
SRR25158380_k127_2826144_0	861299.J421_1261	5.324e-67	238.0	COG0612@1|root,COG0612@2|Bacteria,1ZT7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
SRR25158380_k127_2826144_1	880072.Desac_2741	5.993e-58	217.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1NE6G@1224|Proteobacteria,4321S@68525|delta/epsilon subdivisions,2WWD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158380_k127_2829637_1	671143.DAMO_2346	1.529e-24	115.0	COG0484@1|root,COG3307@1|root,COG0484@2|Bacteria,COG3307@2|Bacteria,2NPHS@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	DnaJ,Wzy_C
SRR25158380_k127_2829637_2	682795.AciX8_2587	0.0001479	54.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria,2JKE0@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16
SRR25158380_k127_2829637_0	439235.Dalk_0708	3.288e-101	346.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR25158380_k127_2830392_0	1173027.Mic7113_3143	7.568e-74	260.0	COG2207@1|root,COG2207@2|Bacteria,1G8PT@1117|Cyanobacteria,1HI07@1150|Oscillatoriales	1117|Cyanobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
SRR25158380_k127_2830392_1	449447.MAE_03280	7.672e-52	194.0	2DVR0@1|root,33WUQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2831365_1	1121943.KB899992_gene2160	4.274e-78	269.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
SRR25158380_k127_2831365_0	1340493.JNIF01000004_gene652	2.282e-258	809.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158380_k127_2831365_8	926562.Oweho_2142	9.154e-12	69.0	COG1225@1|root,COG1225@2|Bacteria,4NGWI@976|Bacteroidetes,1IJ05@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_2831365_5	344747.PM8797T_16535	1.437e-37	145.0	COG3795@1|root,COG3795@2|Bacteria,2J10A@203682|Planctomycetes	203682|Planctomycetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158380_k127_2831365_4	1254432.SCE1572_01530	9.569e-51	187.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158380_k127_2831365_6	204669.Acid345_3899	5.312e-17	83.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	ynjA	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158380_k127_2831365_3	555779.Dthio_PD2550	9.345e-71	244.0	COG0551@1|root,COG0551@2|Bacteria,1RJ2N@1224|Proteobacteria,42T7M@68525|delta/epsilon subdivisions,2WPTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_2831365_2	667014.Thein_0938	3.035e-76	267.0	COG0210@1|root,COG0210@2|Bacteria,2GGRZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF3553,UvrD-helicase,UvrD_C
SRR25158380_k127_2838788_0	204669.Acid345_1052	3.845e-115	391.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_2838788_1	234267.Acid_2681	6.178e-76	259.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
SRR25158380_k127_2842390_5	1385521.N803_02880	5.559e-12	71.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4FGQH@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidoglycan-binding	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158380_k127_2842390_6	179408.Osc7112_1290	2.593e-06	55.0	2E4KA@1|root,32ZF9@2|Bacteria,1G7KH@1117|Cyanobacteria,1HD7J@1150|Oscillatoriales	1117|Cyanobacteria	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
SRR25158380_k127_2842390_0	1173024.KI912151_gene2146	1.275e-200	634.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRR25158380_k127_2842390_1	1502851.FG93_03312	8.366e-78	266.0	COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3JUQU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
SRR25158380_k127_2842390_2	886293.Sinac_3852	1.085e-76	263.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158380_k127_2842390_4	671143.DAMO_0988	6.995e-25	112.0	COG1499@1|root,COG1499@2|Bacteria,2NS26@2323|unclassified Bacteria	2|Bacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
SRR25158380_k127_2842390_3	1123508.JH636456_gene127	7.615e-28	115.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR25158380_k127_2844704_3	1382306.JNIM01000001_gene3896	1.661e-23	104.0	COG2945@1|root,COG2945@2|Bacteria,2G9MQ@200795|Chloroflexi	200795|Chloroflexi	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158380_k127_2844704_2	391625.PPSIR1_04398	4.83e-30	123.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158380_k127_2844704_1	330214.NIDE1061	9.281e-41	158.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158380_k127_2844704_0	1242864.D187_008887	1.925e-163	529.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,EF-hand_5,Metallophos
SRR25158380_k127_2844704_4	1385513.N780_03990	2.937e-05	50.0	COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,2Y9AX@289201|Pontibacillus	91061|Bacilli	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SRR25158380_k127_2845667_3	880526.KE386488_gene1146	1.451e-13	74.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,2FMI3@200643|Bacteroidia,22UXJ@171550|Rikenellaceae	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158380_k127_2845667_2	398767.Glov_0497	1.371e-18	99.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WNZ3@28221|Deltaproteobacteria,43SW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_2845667_1	234267.Acid_4425	2.291e-28	121.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2845667_4	1382359.JIAL01000001_gene2600	1.539e-10	74.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158380_k127_2845667_0	234267.Acid_5939	6.291e-155	505.0	COG1807@1|root,COG1807@2|Bacteria,3Y383@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_2845667_5	1144275.COCOR_05355	2.874e-09	64.0	2ES3U@1|root,33JNT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2851134_2	204669.Acid345_4418	9.15e-50	182.0	2CHAC@1|root,2Z7QK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2851134_0	745014.OMB55_00021820	1.109e-134	442.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158380_k127_2851134_1	204669.Acid345_1443	1.078e-97	330.0	COG1012@1|root,COG1012@2|Bacteria,3Y6J2@57723|Acidobacteria,2JMD6@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158380_k127_2851727_1	234267.Acid_0605	3.213e-54	199.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158380_k127_2851727_0	1499967.BAYZ01000003_gene5884	7.234e-79	271.0	COG2454@1|root,COG2454@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
SRR25158380_k127_2851727_4	1173023.KE650771_gene4214	1.191e-18	98.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
SRR25158380_k127_2851727_3	44056.XP_009040633.1	1.036e-31	138.0	2D0NW@1|root,2SEUV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2851727_5	203122.Sde_2412	2.111e-08	66.0	COG4782@1|root,COG4782@2|Bacteria,1REVW@1224|Proteobacteria,1S55K@1236|Gammaproteobacteria,468W1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
SRR25158380_k127_2851727_2	1284352.AOIG01000027_gene565	3.699e-42	159.0	2CFUA@1|root,32S2G@2|Bacteria,1V63K@1239|Firmicutes,4HMRB@91061|Bacilli,26WRS@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2852914_1	234267.Acid_2848	1.466e-87	299.0	COG1044@1|root,COG1044@2|Bacteria,3Y6ZT@57723|Acidobacteria	57723|Acidobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SRR25158380_k127_2852914_5	392500.Swoo_3062	3.763e-11	74.0	2F10C@1|root,33U1V@2|Bacteria,1NUUY@1224|Proteobacteria,1SNP3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2852914_2	1122216.AUHW01000017_gene1172	1.175e-74	263.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
SRR25158380_k127_2852914_0	1267535.KB906767_gene4766	1.867e-220	702.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_2852914_4	247490.KSU1_D0395	1.449e-25	108.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158380_k127_28597_7	1114856.C496_08906	2.331e-05	57.0	COG0457@1|root,arCOG03408@1|root,arCOG03045@2157|Archaea,arCOG03409@2157|Archaea,2XZFJ@28890|Euryarchaeota,23Z16@183963|Halobacteria	183963|Halobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_12
SRR25158380_k127_28597_6	485913.Krac_9577	2.728e-17	96.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2G88E@200795|Chloroflexi	200795|Chloroflexi	K	SPTR Q471D1 TPR repeat Bacterial transcriptional activator domain Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158380_k127_28597_2	1120973.AQXL01000130_gene1193	6.013e-99	358.0	COG1404@1|root,COG1404@2|Bacteria,1UZRQ@1239|Firmicutes,4HEVW@91061|Bacilli	91061|Bacilli	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8,SLH
SRR25158380_k127_28597_3	344747.PM8797T_09989	1.344e-84	287.0	COG0500@1|root,COG2226@2|Bacteria,2J0NE@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_28597_4	234267.Acid_7537	1.733e-50	187.0	COG2717@1|root,COG2717@2|Bacteria,3Y58Y@57723|Acidobacteria	57723|Acidobacteria	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158380_k127_28597_1	521674.Plim_3769	1.797e-125	409.0	COG2041@1|root,COG2041@2|Bacteria,2J1J7@203682|Planctomycetes	203682|Planctomycetes	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158380_k127_28597_0	1051501.AYTL01000011_gene161	7.343e-138	454.0	COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,1ZC2I@1386|Bacillus	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	yflS	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
SRR25158380_k127_28597_5	469383.Cwoe_3468	1.869e-35	139.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052,OmdA
SRR25158380_k127_28597_8	525904.Tter_1676	6.935e-05	45.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_2860762_6	1170562.Cal6303_4908	4.718e-14	81.0	28K7X@1|root,2Z9VW@2|Bacteria,1G4E1@1117|Cyanobacteria,1HK48@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2860762_0	671143.DAMO_2942	3.447e-103	358.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158380_k127_2860762_3	1128421.JAGA01000001_gene2128	3.795e-27	111.0	2BWQN@1|root,347D7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2860762_2	945713.IALB_2314	3.693e-94	334.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158380_k127_2860762_5	745411.B3C1_04600	1.463e-16	86.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1J5Z7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158380_k127_2860762_1	1380390.JIAT01000009_gene2235	3.208e-97	347.0	COG3055@1|root,COG3055@2|Bacteria,2HQPC@201174|Actinobacteria,4CSAN@84995|Rubrobacteria	84995|Rubrobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2860762_4	1380355.JNIJ01000004_gene2769	1.794e-25	124.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Laminin_G_3,PPC
SRR25158380_k127_2863644_0	986075.CathTA2_1520	4.073e-236	741.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli	91061|Bacilli	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
SRR25158380_k127_2863644_3	1122927.KB895422_gene3825	8.417e-49	183.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,26SKM@186822|Paenibacillaceae	91061|Bacilli	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158380_k127_2863644_1	1267534.KB906754_gene2899	7.626e-98	335.0	COG0154@1|root,COG0154@2|Bacteria,3Y41H@57723|Acidobacteria,2JKKU@204432|Acidobacteriia	204432|Acidobacteriia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158380_k127_2863644_2	1515613.HQ37_02410	1.325e-87	300.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia,22Z0Q@171551|Porphyromonadaceae	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_2863644_4	479434.Sthe_1898	2.131e-32	134.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,27YFE@189775|Thermomicrobia	189775|Thermomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158380_k127_2871081_1	1120973.AQXL01000068_gene19	1.073e-62	224.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,2788T@186823|Alicyclobacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	fadB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01715,ko:K13767	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158380_k127_2871081_0	118163.Ple7327_0557	1.847e-128	428.0	COG3975@1|root,COG3975@2|Bacteria,1G0YP@1117|Cyanobacteria,3VHK8@52604|Pleurocapsales	1117|Cyanobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158380_k127_2873847_1	471854.Dfer_2856	1.052e-90	309.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158380_k127_2873847_0	471854.Dfer_5288	3.383e-119	398.0	COG2252@1|root,COG2252@2|Bacteria,4NGCG@976|Bacteroidetes,47NEQ@768503|Cytophagia	976|Bacteroidetes	S	Permease family	yieG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158380_k127_2873847_2	768670.Calni_0847	1.893e-27	122.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,2GG9I@200930|Deferribacteres	200930|Deferribacteres	G	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SRR25158380_k127_2874224_1	1267535.KB906767_gene640	1.496e-194	617.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria,2JHMR@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158380_k127_2874224_0	404589.Anae109_0854	0.0	2105.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158380_k127_2874224_2	1123242.JH636434_gene3808	3.524e-142	456.0	COG0493@1|root,COG0493@2|Bacteria,2IXFM@203682|Planctomycetes	203682|Planctomycetes	C	COG0493 NADPH-dependent glutamate synthase beta chain and	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158380_k127_287728_0	330214.NIDE2023	3.765e-44	168.0	2C6PZ@1|root,32V0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2877408_5	1210884.HG799462_gene8055	4.024e-11	64.0	COG2271@1|root,COG2271@2|Bacteria,2J4ZG@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_2877408_2	497964.CfE428DRAFT_5423	1.191e-37	151.0	2EPF9@1|root,33H1X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2877408_0	258533.BN977_03703	1.672e-64	238.0	COG1752@1|root,COG1752@2|Bacteria,2I9XW@201174|Actinobacteria,236GN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158380_k127_2877408_1	986075.CathTA2_1906	3.366e-64	223.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli	91061|Bacilli	M	Sortase and related acyltransferases	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158380_k127_2877408_4	204669.Acid345_2272	5.881e-14	76.0	COG2010@1|root,COG2010@2|Bacteria,3Y5ZT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158380_k127_2879242_1	1267535.KB906767_gene3229	1.086e-169	540.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158380_k127_2879242_0	306281.AJLK01000150_gene1926	7.418e-202	635.0	COG0499@1|root,COG0499@2|Bacteria,1G1MN@1117|Cyanobacteria,1JJ5C@1189|Stigonemataceae	1117|Cyanobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158380_k127_2879242_2	1267533.KB906737_gene1620	1.052e-75	280.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
SRR25158380_k127_2890367_4	309801.trd_A0708	6.442e-33	135.0	COG1680@1|root,COG1680@2|Bacteria,2GAJ8@200795|Chloroflexi,27YVH@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_2890367_5	485918.Cpin_4360	6.424e-08	62.0	2DGDA@1|root,2ZVHU@2|Bacteria,4P82A@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
SRR25158380_k127_2890367_0	1254432.SCE1572_42880	7.931e-85	295.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MC0@68525|delta/epsilon subdivisions,2WJIC@28221|Deltaproteobacteria,2YX8D@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25,3.6.3.29,3.6.3.55	ko:K02017,ko:K02045,ko:K15497	ko00920,ko02010,map00920,map02010	M00185,M00189,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5,3.A.1.8	-	-	ABC_tran,TOBE_2,TOBE_3
SRR25158380_k127_2890367_2	1112274.KI911560_gene55	7.267e-52	193.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KMAW@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM sulfate ABC transporter, inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158380_k127_2890367_1	324057.Pjdr2_1262	1.506e-63	233.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,4HEKX@91061|Bacilli,275TN@186822|Paenibacillaceae	91061|Bacilli	P	Sulfate ABC transporter substrate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRR25158380_k127_2890367_3	903818.KI912268_gene674	1.647e-36	158.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
SRR25158380_k127_289202_0	234267.Acid_0772	1.404e-92	327.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
SRR25158380_k127_289202_2	240015.ACP_2639	5.048e-87	301.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR25158380_k127_289202_1	234267.Acid_6203	9.542e-89	299.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158380_k127_289202_3	1267534.KB906754_gene3342	2.238e-47	175.0	COG0764@1|root,COG0764@2|Bacteria,3Y7I3@57723|Acidobacteria,2JP4P@204432|Acidobacteriia	204432|Acidobacteriia	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158380_k127_289202_5	768670.Calni_0301	7.705e-06	56.0	COG2825@1|root,COG2825@2|Bacteria,2GFRM@200930|Deferribacteres	200930|Deferribacteres	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158380_k127_289202_4	1267534.KB906754_gene3361	1.515e-06	57.0	COG2825@1|root,COG2825@2|Bacteria,3Y56P@57723|Acidobacteria,2JP1P@204432|Acidobacteriia	204432|Acidobacteriia	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158380_k127_2898835_1	240015.ACP_2112	1.376e-24	121.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y2ZI@57723|Acidobacteria,2JIKK@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158380_k127_2898835_0	926569.ANT_22550	4.617e-90	305.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158380_k127_2899456_1	1033743.CAES01000033_gene1029	1.116e-71	247.0	COG0363@1|root,COG0363@2|Bacteria,1V1UT@1239|Firmicutes,4HFPX@91061|Bacilli,26R90@186822|Paenibacillaceae	91061|Bacilli	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
SRR25158380_k127_2899456_0	1333507.AUTQ01000131_gene467	1.673e-77	281.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,2Q5DK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158380_k127_2899456_2	926550.CLDAP_25590	5.117e-43	173.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,DUF3367,DUF4091,DUF4159
SRR25158380_k127_2901130_0	1183438.GKIL_4354	4.044e-232	747.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_2901130_1	82654.Pse7367_3259	6.803e-37	145.0	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1G4XP@1117|Cyanobacteria	1117|Cyanobacteria	M	Peptidase M15B M15C, D,D-carboxypeptidase VanY endolysins	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VanY
SRR25158380_k127_2902493_9	204669.Acid345_0217	1.549e-43	166.0	COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria,2JI2B@204432|Acidobacteriia	204432|Acidobacteriia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158380_k127_2902493_14	326427.Cagg_1197	5.04e-21	98.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,375F5@32061|Chloroflexia	32061|Chloroflexia	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158380_k127_2902493_4	1340493.JNIF01000003_gene3084	1.249e-116	390.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria	57723|Acidobacteria	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158380_k127_2902493_1	240015.ACP_2349	4.297e-211	674.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158380_k127_2902493_5	1235835.C814_02935	9.642e-89	300.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WGTZ@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158380_k127_2902493_8	1340493.JNIF01000003_gene2685	4.236e-70	246.0	COG1475@1|root,COG1475@2|Bacteria,3Y40Y@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158380_k127_2902493_16	441769.ABFU01000064_gene1780	0.000368	49.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
SRR25158380_k127_2902493_15	1121920.AUAU01000005_gene1105	3.648e-08	61.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109,ko:K18682	ko00190,ko00195,ko01100,ko03018,map00190,map00195,map01100,map03018	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03019	3.A.2.1	-	-	ATP-synt_B
SRR25158380_k127_2902493_13	682795.AciX8_2038	7.415e-27	117.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria,2JJM8@204432|Acidobacteriia	204432|Acidobacteriia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158380_k127_2902493_0	1340493.JNIF01000004_gene349	1.116e-234	736.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158380_k127_2902493_6	234267.Acid_0464	3.357e-88	302.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158380_k127_2902493_11	56780.SYN_03077	1.698e-36	143.0	COG5652@1|root,COG5652@2|Bacteria,1PUUC@1224|Proteobacteria,43F3B@68525|delta/epsilon subdivisions,2X381@28221|Deltaproteobacteria,2MSC7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158380_k127_2902493_3	1120746.CCNL01000006_gene373	5.143e-132	431.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SRR25158380_k127_2902493_2	204669.Acid345_2370	1.08e-156	507.0	COG0304@1|root,COG0304@2|Bacteria,3Y43C@57723|Acidobacteria,2JMFI@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158380_k127_2902493_12	443144.GM21_3234	2.559e-35	144.0	COG0500@1|root,COG2226@2|Bacteria,1QYSR@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158380_k127_2902493_10	309807.SRU_1596	1.176e-38	160.0	COG0654@1|root,COG0654@2|Bacteria,4PM2V@976|Bacteroidetes,1FJWJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
SRR25158380_k127_2902493_7	1267534.KB906758_gene2303	3.571e-75	265.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Y@57723|Acidobacteria,2JKVG@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_2915495_3	479432.Sros_6660	3.267e-43	170.0	2BXSN@1|root,2ZAB3@2|Bacteria,2I1VJ@201174|Actinobacteria,4EPCA@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
SRR25158380_k127_2915495_1	1210884.HG799465_gene12146	1.856e-86	302.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158380_k127_2915495_2	886377.Murru_0131	2.205e-43	166.0	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1HZF0@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158380_k127_2915495_4	1385518.N798_13720	6.243e-08	61.0	COG0454@1|root,COG0456@2|Bacteria,2HXG9@201174|Actinobacteria,4FGIR@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_2915495_0	1449976.KALB_4790	1.424e-87	296.0	COG0684@1|root,COG0684@2|Bacteria,2I9PH@201174|Actinobacteria,4DZ2D@85010|Pseudonocardiales	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158380_k127_2926632_0	1267580.AF6_0190	7.645e-141	471.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,21W9Q@150247|Anoxybacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158380_k127_2926632_1	391008.Smal_0670	2.172e-08	63.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1X503@135614|Xanthomonadales	135614|Xanthomonadales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
SRR25158380_k127_2933022_1	383372.Rcas_3282	2.855e-89	305.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158380_k127_2933022_0	269799.Gmet_0135	4.831e-124	413.0	COG1109@1|root,COG1109@2|Bacteria,1R96J@1224|Proteobacteria,42PM2@68525|delta/epsilon subdivisions,2WKSP@28221|Deltaproteobacteria,43T3P@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_2933022_5	1437425.CSEC_1101	2.337e-15	76.0	2E4YG@1|root,32ZSB@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
SRR25158380_k127_2933022_2	552811.Dehly_0097	3.042e-64	229.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,34CTQ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158380_k127_2933022_3	402777.KB235903_gene1919	3.384e-30	120.0	COG1598@1|root,COG1598@2|Bacteria,1G9X3@1117|Cyanobacteria,1HDAI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158380_k127_2933022_4	402777.KB235903_gene1918	1.089e-15	78.0	COG1724@1|root,COG1724@2|Bacteria,1G90Q@1117|Cyanobacteria,1HCXJ@1150|Oscillatoriales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158380_k127_2941502_0	886293.Sinac_4730	1.848e-227	721.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158380_k127_2941502_1	1173020.Cha6605_2960	7.328e-41	158.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158380_k127_2941502_2	1168034.FH5T_02835	1.504e-36	141.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,2FUDQ@200643|Bacteroidia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_2941502_3	330214.NIDE4254	2.09e-24	103.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_294550_1	1174528.JH992898_gene3099	3.919e-48	192.0	COG4485@1|root,COG4485@2|Bacteria,1GGV1@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_294550_0	234267.Acid_1421	8.797e-59	226.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158380_k127_2956534_0	468059.AUHA01000002_gene913	5.021e-313	971.0	COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,4NFQX@976|Bacteroidetes,1IQS5@117747|Sphingobacteriia	976|Bacteroidetes	C	Serves to protect cells from the toxic effects of hydrogen peroxide	katE	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel,DJ-1_PfpI
SRR25158380_k127_2956534_1	795666.MW7_1939	6.91e-69	239.0	COG1633@1|root,COG1633@2|Bacteria,1RB01@1224|Proteobacteria,2VQJI@28216|Betaproteobacteria,1K7GH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158380_k127_2956534_2	985255.APHJ01000018_gene3019	3.239e-08	54.0	2E3Q4@1|root,32YN3@2|Bacteria,4NVYD@976|Bacteroidetes,1ICUD@117743|Flavobacteriia,2P7MI@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2958125_2	290397.Adeh_0784	3.73e-68	239.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158380_k127_2958125_0	1411123.JQNH01000001_gene3173	1.325e-92	314.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2U62M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158380_k127_2958125_3	639030.JHVA01000001_gene2516	4.646e-21	101.0	COG0357@1|root,COG0357@2|Bacteria,3Y4W7@57723|Acidobacteria,2JJG7@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158380_k127_2958125_1	1173028.ANKO01000147_gene1308	7.529e-89	311.0	COG0076@1|root,COG0076@2|Bacteria,1G3F8@1117|Cyanobacteria,1H9S6@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86	ko:K01580,ko:K01593,ko:K13745	ko00250,ko00260,ko00350,ko00360,ko00380,ko00410,ko00430,ko00650,ko00901,ko00950,ko00965,ko01100,ko01110,ko01120,ko02024,ko04726,ko04727,ko04728,ko04940,ko05030,ko05031,ko05034,map00250,map00260,map00350,map00360,map00380,map00410,map00430,map00650,map00901,map00950,map00965,map01100,map01110,map01120,map02024,map04726,map04727,map04728,map04940,map05030,map05031,map05034	M00027,M00037,M00042	R00261,R00489,R00685,R00699,R00736,R01682,R02080,R02466,R02701,R04909,R07650	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158380_k127_295856_3	78245.Xaut_3953	5.242e-29	120.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,3EYF7@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158380_k127_295856_1	317936.Nos7107_5200	9.454e-126	411.0	COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria,1HMG3@1161|Nostocales	1117|Cyanobacteria	P	Phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158380_k127_295856_2	251221.35210569	1.791e-121	398.0	COG0573@1|root,COG0573@2|Bacteria,1G1JR@1117|Cyanobacteria	1117|Cyanobacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158380_k127_295856_0	530564.Psta_2805	1.79e-131	427.0	COG0226@1|root,COG0226@2|Bacteria,2IYX0@203682|Planctomycetes	203682|Planctomycetes	P	COG0226 ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
SRR25158380_k127_2958864_3	1122919.KB905550_gene1894	3.732e-09	62.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26S7H@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158380_k127_2958864_0	1382359.JIAL01000001_gene1975	7.797e-123	408.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_2958864_1	1047013.AQSP01000140_gene2478	3.52e-102	344.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
SRR25158380_k127_2958864_2	1089553.Tph_c12600	1.074e-82	293.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,42EWR@68295|Thermoanaerobacterales	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_2962611_2	1379698.RBG1_1C00001G1704	4.921e-16	81.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2962611_4	2325.TKV_c08930	0.0004918	50.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,42GU0@68295|Thermoanaerobacterales	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
SRR25158380_k127_2962611_3	56780.SYN_00516	1.76e-07	63.0	COG1664@1|root,COG1664@2|Bacteria,1MUS9@1224|Proteobacteria,43BNZ@68525|delta/epsilon subdivisions,2X70B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2962611_1	234267.Acid_3637	7.091e-55	208.0	COG0250@1|root,COG0250@2|Bacteria,3Y3I1@57723|Acidobacteria	57723|Acidobacteria	K	Participates in transcription elongation, termination and antitermination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2962611_0	234267.Acid_5882	6.576e-88	304.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_296769_2	1232410.KI421428_gene1030	6.561e-32	125.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_296769_0	204669.Acid345_3520	1.386e-311	965.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria,2JI3Z@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158380_k127_296769_1	420246.GTNG_2491	3.619e-38	158.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1WFJ0@129337|Geobacillus	91061|Bacilli	S	AI-2E family transporter	yrrI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158380_k127_298763_3	278963.ATWD01000002_gene823	1.409e-45	192.0	COG0457@1|root,COG0457@2|Bacteria,3Y59I@57723|Acidobacteria,2JJNP@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_298763_1	1122604.JONR01000025_gene4602	8.64e-75	288.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158380_k127_298763_0	234267.Acid_1368	9.564e-124	447.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.1.37,2.7.11.1	ko:K00870,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Guanylate_cyc,Pkinase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158380_k127_298763_2	1183438.GKIL_3942	5.126e-57	203.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158380_k127_2991828_4	1396141.BATP01000038_gene1207	2.458e-122	400.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158380_k127_2991828_3	1380391.JIAS01000011_gene5524	2.415e-170	552.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,2JW5I@204441|Rhodospirillales	204441|Rhodospirillales	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158380_k127_2991828_2	926569.ANT_24910	7.254e-216	682.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158380_k127_2991828_0	1382359.JIAL01000001_gene1410	1.269e-320	997.0	COG3250@1|root,COG3250@2|Bacteria,3Y6CM@57723|Acidobacteria,2JKZF@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_2991828_1	1502852.FG94_00930	1.267e-241	766.0	COG3250@1|root,COG3250@2|Bacteria,1NTQW@1224|Proteobacteria	1224|Proteobacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_2_N
SRR25158380_k127_2991890_2	1057002.KB905370_gene2688	1.97e-05	50.0	COG0500@1|root,COG2226@2|Bacteria,1RD2T@1224|Proteobacteria,2VBBK@28211|Alphaproteobacteria,4BJ74@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_2991890_1	234267.Acid_3032	1.393e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,3Y4KN@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158380_k127_2991890_0	375286.mma_1733	1.075e-99	332.0	COG0697@1|root,COG0803@1|root,COG0697@2|Bacteria,COG0803@2|Bacteria,1N3FA@1224|Proteobacteria,2VHAD@28216|Betaproteobacteria,476CV@75682|Oxalobacteraceae	28216|Betaproteobacteria	EG	EamA-like transporter family	cnrT	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158380_k127_2992046_1	234267.Acid_3223	1.089e-10	66.0	28ZVZ@1|root,2ZMKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2992046_0	204669.Acid345_4392	1.351e-157	533.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158380_k127_2999806_0	1267533.KB906737_gene1874	3.671e-223	697.0	COG3285@1|root,COG3285@2|Bacteria,3Y715@57723|Acidobacteria,2JM5P@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2999806_1	857087.Metme_1575	4.23e-89	305.0	COG0457@1|root,COG0457@2|Bacteria,1R6ZR@1224|Proteobacteria,1RRKI@1236|Gammaproteobacteria,1XDM3@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
SRR25158380_k127_3007720_0	1121904.ARBP01000035_gene1749	1.693e-38	148.0	COG2020@1|root,COG2020@2|Bacteria,4NM9P@976|Bacteroidetes,47RDW@768503|Cytophagia	976|Bacteroidetes	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158380_k127_3007720_4	1121456.ATVA01000012_gene2522	1.623e-06	60.0	COG4313@1|root,COG4313@2|Bacteria,1N1DR@1224|Proteobacteria,432MC@68525|delta/epsilon subdivisions,2WXBW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3007720_1	309807.SRU_2819	1.099e-27	120.0	COG0526@1|root,COG0526@2|Bacteria,4PIEG@976|Bacteroidetes,1FK6M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_3007720_3	1125863.JAFN01000001_gene2225	9.022e-11	66.0	COG2608@1|root,COG2608@2|Bacteria,1Q35K@1224|Proteobacteria,433Y4@68525|delta/epsilon subdivisions,2WYDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
SRR25158380_k127_3007720_2	485913.Krac_6370	9.16e-17	83.0	arCOG13956@1|root,33BWW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3008314_2	1089547.KB913013_gene3993	9.87e-08	60.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47K73@768503|Cytophagia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
SRR25158380_k127_3008314_0	886293.Sinac_0554	9.638e-103	349.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,2J2EJ@203682|Planctomycetes	203682|Planctomycetes	KLT	Forkhead associated domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
SRR25158380_k127_3008314_3	1382306.JNIM01000001_gene1833	0.0004102	52.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi	200795|Chloroflexi	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158380_k127_3008314_1	1144275.COCOR_02951	7.417e-56	216.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SRR25158380_k127_3016638_1	1267533.KB906744_gene83	1.502e-158	511.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158380_k127_3016638_3	1047013.AQSP01000139_gene2414	3.255e-32	136.0	COG0457@1|root,COG0457@2|Bacteria,2NRWN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3016638_2	404589.Anae109_1214	1.088e-68	241.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2Z36A@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158380_k127_3016638_4	1461577.CCMH01000013_gene717	3.611e-31	126.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I4A2@117743|Flavobacteriia	976|Bacteroidetes	M	30S ribosomal protein S23	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_3016638_0	404589.Anae109_1213	5.132e-232	729.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158380_k127_3016638_5	502025.Hoch_3248	5.471e-07	52.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158380_k127_30203_0	1499967.BAYZ01000069_gene1838	7.289e-134	438.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158380_k127_30203_7	316274.Haur_3709	3.374e-22	111.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_30203_1	204669.Acid345_3265	3.038e-131	428.0	COG0451@1|root,COG0451@2|Bacteria,3Y3CF@57723|Acidobacteria,2JI4M@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158380_k127_30203_3	1124780.ANNU01000028_gene955	2.429e-89	307.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158380_k127_30203_6	1385935.N836_33000	3.003e-25	116.0	COG0500@1|root,COG2226@2|Bacteria,1GQNU@1117|Cyanobacteria,1HHXR@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158380_k127_30203_4	316274.Haur_3712	2.257e-61	229.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_30203_5	383372.Rcas_1662	2.337e-29	130.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi,375A8@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SRR25158380_k127_30203_2	330214.NIDE3348	8.254e-128	421.0	COG2192@1|root,COG2192@2|Bacteria	2|Bacteria	O	nodulation	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158380_k127_3024309_1	682795.AciX8_3716	7.216e-176	577.0	COG1629@1|root,COG4771@2|Bacteria,3Y3WR@57723|Acidobacteria,2JIZP@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_3024309_0	1382359.JIAL01000001_gene1531	0.0	1462.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158380_k127_3024309_2	1121101.HMPREF1532_04085	2.204e-28	121.0	COG0383@1|root,COG1404@1|root,COG0383@2|Bacteria,COG1404@2|Bacteria,4NJ12@976|Bacteroidetes,2FNHX@200643|Bacteroidia,4AMY9@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 38 C-terminal domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,F5_F8_type_C,Glyco_hydro_38,Glyco_hydro_38C
SRR25158380_k127_3037173_1	1267533.KB906735_gene5073	6.547e-42	168.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158380_k127_3037173_2	644966.Tmar_1104	1.978e-21	98.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158380_k127_3037173_0	1121428.DESHY_50103___1	1.645e-75	260.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_30457_3	1267534.KB906755_gene4690	8.106e-41	159.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315,ko:K16928	-	M00582	-	-	ko00000,ko00002,ko01000,ko02000,ko03021	3.A.1.33	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
SRR25158380_k127_30457_1	1267533.KB906733_gene2988	7.369e-106	349.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_30457_0	1267533.KB906733_gene2989	2.189e-153	504.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_30457_2	1382306.JNIM01000001_gene910	1.252e-92	313.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_3045903_0	234267.Acid_1644	4.728e-111	367.0	COG1629@1|root,COG4771@2|Bacteria,3Y7B4@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_3046048_2	1267533.KB906734_gene4022	5.448e-107	357.0	COG0438@1|root,COG0438@2|Bacteria,3Y5K5@57723|Acidobacteria,2JNE3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3046048_1	59374.Fisuc_2256	8.412e-160	508.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	uxs	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158380_k127_3046048_5	1232410.KI421422_gene2024	4.18e-07	53.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria,43VFU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_3046048_3	105559.Nwat_0046	4.115e-30	121.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_3046048_0	1123368.AUIS01000027_gene1355	8.545e-191	615.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158380_k127_3046048_4	1173028.ANKO01000148_gene1371	2.84e-11	66.0	COG0463@1|root,COG0463@2|Bacteria,1G20E@1117|Cyanobacteria,1H9C4@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_3049165_1	330214.NIDE4314	1.042e-31	125.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3049165_0	913325.N799_11580	2.681e-96	330.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,1X38Y@135614|Xanthomonadales	135614|Xanthomonadales	P	receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
SRR25158380_k127_3051602_2	1296416.JACB01000001_gene3358	4.803e-19	91.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia,2YKRI@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_3051602_3	521045.Kole_1207	8.57e-10	65.0	2FCRF@1|root,344UM@2|Bacteria,2GE8C@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3051602_4	458817.Shal_2384	2.071e-07	58.0	2E4KA@1|root,32ZF9@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
SRR25158380_k127_3051602_5	756067.MicvaDRAFT_3890	4.491e-06	55.0	COG3103@1|root,COG3103@2|Bacteria,1G4VS@1117|Cyanobacteria,1H942@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM SH3 type 3	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158380_k127_3051602_1	204669.Acid345_0751	5.787e-137	450.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3051602_0	1173024.KI912149_gene5262	2.309e-175	561.0	COG1816@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG5278@1|root,COG1816@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5278@2|Bacteria,1GK1J@1117|Cyanobacteria,1JKBT@1189|Stigonemataceae	1117|Cyanobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158380_k127_3054668_1	56107.Cylst_4555	1.073e-32	139.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
SRR25158380_k127_3054668_2	760192.Halhy_5193	5.449e-19	93.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,DUF4440,SnoaL_3
SRR25158380_k127_3054668_0	309801.trd_A0425	5.001e-118	399.0	COG2268@1|root,COG2268@2|Bacteria,2GBEI@200795|Chloroflexi,27Z5S@189775|Thermomicrobia	189775|Thermomicrobia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SRR25158380_k127_3054668_3	1120960.ATXG01000018_gene1383	4.862e-05	52.0	COG1585@1|root,COG1585@2|Bacteria,2IRJ7@201174|Actinobacteria,4FSSB@85023|Microbacteriaceae	201174|Actinobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158380_k127_3058272_2	935567.JAES01000045_gene2571	2.055e-28	121.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria,1X44K@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158380_k127_3058272_1	378806.STAUR_0399	2.126e-29	129.0	COG0517@1|root,COG0517@2|Bacteria,1N9X9@1224|Proteobacteria,4375S@68525|delta/epsilon subdivisions,2X9SS@28221|Deltaproteobacteria,2YXN7@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_3058272_3	472759.Nhal_1380	4.335e-18	89.0	COG0071@1|root,COG0071@2|Bacteria,1NPJI@1224|Proteobacteria,1SRY5@1236|Gammaproteobacteria,1X21C@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158380_k127_3058272_0	472759.Nhal_1379	1.588e-104	353.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1S0BH@1236|Gammaproteobacteria,1X076@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158380_k127_3077285_4	1124780.ANNU01000088_gene304	2.125e-15	83.0	2AWH3@1|root,31NDJ@2|Bacteria,4NRPZ@976|Bacteroidetes,47SFU@768503|Cytophagia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
SRR25158380_k127_3077285_0	1463895.JODA01000040_gene2349	8.929e-59	217.0	COG3361@1|root,COG3361@2|Bacteria,2H1AK@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
SRR25158380_k127_3077285_2	1340493.JNIF01000004_gene73	6.175e-21	105.0	COG3712@1|root,COG3712@2|Bacteria,3Y5MB@57723|Acidobacteria	57723|Acidobacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158380_k127_3077285_3	642492.Clole_0140	1.469e-18	90.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158380_k127_3077285_1	1385513.N780_14215	1.464e-33	146.0	COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes,4HA25@91061|Bacilli,2Y9MH@289201|Pontibacillus	91061|Bacilli	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158380_k127_3077285_5	246194.CHY_1108	1.224e-07	58.0	COG1266@1|root,COG1266@2|Bacteria,1UUMR@1239|Firmicutes,25CF0@186801|Clostridia,42GZJ@68295|Thermoanaerobacterales	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158380_k127_3082025_1	700598.Niako_5962	4.091e-191	607.0	COG5434@1|root,COG5434@2|Bacteria,4NZZQ@976|Bacteroidetes,1IX33@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
SRR25158380_k127_3082025_0	234267.Acid_2820	2.765e-238	745.0	COG1501@1|root,COG1501@2|Bacteria,3Y35Y@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Glycoside hydrolase, clan GH-D	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,Melibiase_2_C
SRR25158380_k127_3082025_3	1380391.JIAS01000012_gene4522	6.248e-13	72.0	2C8GR@1|root,2ZR4Z@2|Bacteria,1P812@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3082025_2	29581.BW37_04034	1.507e-63	224.0	COG3220@1|root,COG3220@2|Bacteria,1RH40@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
SRR25158380_k127_3083492_1	714943.Mucpa_6664	1.745e-183	587.0	COG5434@1|root,COG5434@2|Bacteria,4NI6V@976|Bacteroidetes	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
SRR25158380_k127_3083492_5	1198114.AciX9_2754	1.164e-99	333.0	COG0583@1|root,COG0583@2|Bacteria,3Y31P@57723|Acidobacteria,2JIC0@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158380_k127_3083492_2	1121920.AUAU01000037_gene2735	1.482e-149	485.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158380_k127_3083492_4	1121468.AUBR01000010_gene2457	9.944e-122	402.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,42EV4@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_3083492_0	292459.STH2116	1.73e-226	710.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158380_k127_3083492_6	1444309.JAQG01000106_gene1107	2.675e-81	276.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,26RMU@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158380_k127_3083492_7	1396141.BATP01000061_gene4541	3.029e-49	183.0	28N64@1|root,2ZBFG@2|Bacteria,46Z9S@74201|Verrucomicrobia,2IWQS@203494|Verrucomicrobiae	2|Bacteria	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
SRR25158380_k127_3083492_3	880073.Calab_0031	7.336e-131	429.0	COG2017@1|root,COG2017@2|Bacteria,2NQA5@2323|unclassified Bacteria	2|Bacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158380_k127_3083492_8	497964.CfE428DRAFT_4748	3.754e-48	175.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_3087960_0	247490.KSU1_D0506	2.203e-175	572.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158380_k127_3089212_0	234267.Acid_4210	8.661e-194	610.0	COG3669@1|root,COG3669@2|Bacteria,3Y43P@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
SRR25158380_k127_3089212_4	756272.Plabr_3926	9.114e-85	289.0	COG3618@1|root,COG3618@2|Bacteria,2IZD1@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158380_k127_3089212_3	1210884.HG799478_gene15504	5.541e-88	301.0	COG0451@1|root,COG0451@2|Bacteria,2IYKN@203682|Planctomycetes	203682|Planctomycetes	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158380_k127_3089212_1	56107.Cylst_1796	2.504e-147	477.0	COG1063@1|root,COG1063@2|Bacteria,1G360@1117|Cyanobacteria,1HJDW@1161|Nostocales	2|Bacteria	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_3089212_5	439292.Bsel_2453	7.055e-81	275.0	COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,26NE3@186821|Sporolactobacillaceae	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158380_k127_3089212_2	234267.Acid_5762	2.783e-142	467.0	COG1139@1|root,COG1139@2|Bacteria,3Y3R8@57723|Acidobacteria	57723|Acidobacteria	C	cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158380_k127_3089212_7	1173028.ANKO01000220_gene584	5.527e-22	105.0	COG1556@1|root,COG1556@2|Bacteria	2|Bacteria	S	LUD domain	lldG	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158380_k127_3089212_6	1462527.CCDM010000006_gene4704	5.635e-78	271.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,23MKV@182709|Oceanobacillus	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158380_k127_3099772_1	1150864.MILUP08_41199	3.648e-08	61.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4DFSJ@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158380_k127_3099772_0	1185876.BN8_04256	6.715e-26	111.0	COG0296@1|root,COG1680@1|root,COG0296@2|Bacteria,COG1680@2|Bacteria,4NG6Z@976|Bacteroidetes,47PR8@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Beta-lactamase
SRR25158380_k127_3102004_1	671143.DAMO_0706	3.985e-85	288.0	COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158380_k127_3102004_0	204669.Acid345_2458	3.92e-197	627.0	COG1003@1|root,COG1003@2|Bacteria,3Y2UZ@57723|Acidobacteria,2JIAN@204432|Acidobacteriia	204432|Acidobacteriia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158380_k127_3102004_2	240015.ACP_1550	9.785e-28	116.0	COG1695@1|root,COG1695@2|Bacteria,3Y4WY@57723|Acidobacteria,2JJYG@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_3102004_3	234267.Acid_7177	1.281e-13	74.0	COG0577@1|root,COG0577@2|Bacteria,3Y402@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_3103391_0	204669.Acid345_1052	1.047e-180	598.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_3103391_2	502025.Hoch_1576	9.29e-55	197.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_3103391_3	1318628.MARLIPOL_13014	3.01e-19	96.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,1S96R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_3103391_1	479434.Sthe_2283	3.646e-95	327.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3103391_4	504472.Slin_3353	2.605e-17	91.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,47XT1@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158380_k127_3103391_5	1128421.JAGA01000002_gene1525	8.987e-10	62.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158380_k127_3109844_1	1267534.KB906757_gene1007	3.647e-74	260.0	2C0ZI@1|root,2ZAKK@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
SRR25158380_k127_3109844_0	234267.Acid_2975	3.598e-107	376.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_3117597_1	682795.AciX8_4447	4.861e-65	233.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
SRR25158380_k127_3117597_0	1242864.D187_001445	5.771e-109	359.0	COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,438ZF@68525|delta/epsilon subdivisions,2X44Q@28221|Deltaproteobacteria,2YY90@29|Myxococcales	28221|Deltaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
SRR25158380_k127_3117597_2	861299.J421_4534	6.7e-17	85.0	COG3682@1|root,COG3682@2|Bacteria,1ZV3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158380_k127_3117597_4	886293.Sinac_3923	3.829e-06	57.0	COG4219@1|root,COG4219@2|Bacteria,2J2DC@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158380_k127_3122506_1	272134.KB731325_gene694	2.943e-155	497.0	COG4941@1|root,COG4941@2|Bacteria,1G1YQ@1117|Cyanobacteria,1H7AG@1150|Oscillatoriales	1117|Cyanobacteria	K	RNA polymerase, sigma subunit, ECF family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_3122506_3	272134.KB731324_gene6666	1.601e-52	187.0	COG3795@1|root,COG3795@2|Bacteria,1G6M3@1117|Cyanobacteria,1HBWD@1150|Oscillatoriales	1117|Cyanobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158380_k127_3122506_7	1122164.JHWF01000010_gene2390	7.625e-07	51.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,1SCHM@1236|Gammaproteobacteria,1JG61@118969|Legionellales	118969|Legionellales	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRR25158380_k127_3122506_4	1123508.JH636439_gene967	2.917e-50	182.0	COG3795@1|root,COG3795@2|Bacteria,2J041@203682|Planctomycetes	203682|Planctomycetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158380_k127_3122506_5	1121015.N789_03795	1.321e-45	167.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,1S6KT@1236|Gammaproteobacteria,1X7NJ@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
SRR25158380_k127_3122506_0	401053.AciPR4_1363	3.748e-182	579.0	COG0666@1|root,COG0666@2|Bacteria,3Y3EY@57723|Acidobacteria	57723|Acidobacteria	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3122506_2	886293.Sinac_3851	8.419e-85	286.0	COG1926@1|root,COG1926@2|Bacteria,2J36S@203682|Planctomycetes	203682|Planctomycetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158380_k127_3122506_6	1216976.AX27061_4446	7.735e-14	72.0	2B7KW@1|root,320RZ@2|Bacteria,1RJSP@1224|Proteobacteria,2VTD1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3123537_3	251221.35210840	1.938e-13	83.0	COG1629@1|root,COG4771@2|Bacteria,1G3RJ@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM TonB-dependent heme hemoglobin receptor family protein	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	AMIN,Plug,TonB_dep_Rec
SRR25158380_k127_3123537_1	1303518.CCALI_02289	1.319e-36	149.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
SRR25158380_k127_3123537_0	194867.ALBQ01000057_gene3416	1.472e-49	181.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2K4GG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158380_k127_3123537_2	1123322.KB904634_gene2311	1.692e-35	147.0	28MYG@1|root,2ZB5C@2|Bacteria,2H19V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3123537_4	530564.Psta_2706	0.0004424	45.0	COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158380_k127_3124375_5	1121333.JMLH01000043_gene2603	1.478e-11	64.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,3VPIA@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158380_k127_3124375_4	1121918.ARWE01000001_gene3511	5.023e-33	132.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,43SJV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158380_k127_3124375_2	321332.CYB_0455	6.302e-76	262.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SRR25158380_k127_3124375_3	639030.JHVA01000001_gene3632	7.004e-59	213.0	COG1215@1|root,COG1215@2|Bacteria,3Y3PN@57723|Acidobacteria,2JHSE@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_3124375_1	1121920.AUAU01000007_gene408	2.975e-84	305.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158380_k127_3124375_0	234267.Acid_3204	1.729e-182	592.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158380_k127_3131309_1	1267533.KB906733_gene3119	3.828e-75	278.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria,2JKNM@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,UnbV_ASPIC,VCBS
SRR25158380_k127_3131309_0	215803.DB30_3001	2.112e-129	419.0	COG0715@1|root,COG0715@2|Bacteria,1RKKF@1224|Proteobacteria,43AHB@68525|delta/epsilon subdivisions,2X5XF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158380_k127_3131535_5	1089553.Tph_c01480	3.534e-28	123.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,42GTS@68295|Thermoanaerobacterales	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158380_k127_3131535_2	234267.Acid_0264	6.979e-106	366.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
SRR25158380_k127_3131535_7	639030.JHVA01000001_gene3990	4.586e-08	64.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	204432|Acidobacteriia	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158380_k127_3131535_6	1173029.JH980292_gene2288	1.453e-13	80.0	COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HH3D@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_3131535_4	204669.Acid345_1221	2.24e-65	224.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158380_k127_3131535_3	706587.Desti_5258	3.541e-67	231.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MRJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158380_k127_3131535_0	1162668.LFE_0879	1.486e-282	884.0	COG0480@1|root,COG0480@2|Bacteria,3J0EK@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158380_k127_3131535_1	234267.Acid_5120	3.086e-186	585.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria	57723|Acidobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158380_k127_3140835_3	1535422.ND16A_3501	9.653e-13	72.0	COG3595@1|root,COG3595@2|Bacteria,1NG89@1224|Proteobacteria,1SCZV@1236|Gammaproteobacteria,2Q846@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158380_k127_3140835_2	204669.Acid345_1037	8.423e-54	212.0	COG3595@1|root,COG3595@2|Bacteria,3Y97I@57723|Acidobacteria,2JNRB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3140835_0	1379698.RBG1_1C00001G1080	2.054e-90	329.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158380_k127_3140835_1	1379698.RBG1_1C00001G1080	5.768e-82	302.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158380_k127_3143113_0	251229.Chro_4009	5.223e-119	421.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SRR25158380_k127_3143113_1	497964.CfE428DRAFT_4880	5.9e-110	374.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,46T28@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_31
SRR25158380_k127_3143113_3	234267.Acid_0228	6.144e-69	253.0	COG2890@1|root,COG2890@2|Bacteria,3Y8Q3@57723|Acidobacteria	2|Bacteria	J	Pfam:Methyltransf_26	rsmC	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	MTS
SRR25158380_k127_3143113_4	1288494.EBAPG3_5910	3.504e-67	237.0	2C6PZ@1|root,2Z7SD@2|Bacteria,1R982@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3143113_2	330214.NIDE2011	3.296e-103	355.0	COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria	2|Bacteria	S	type VI secretion protein	sciH	-	-	ko:K11900,ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
SRR25158380_k127_3143113_5	448385.sce2703	2.162e-35	149.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123,FHA,GAF_2,Tail_P2_I,Yop-YscD_cpl
SRR25158380_k127_3143113_6	1198452.Jab_2c06950	1.442e-27	114.0	COG4104@1|root,COG4104@2|Bacteria	2|Bacteria	T	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
SRR25158380_k127_3145494_3	266117.Rxyl_3167	7.883e-40	152.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158380_k127_3145494_2	1382359.JIAL01000001_gene1871	4.689e-111	398.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158380_k127_3145494_0	1163617.SCD_n00323	3.267e-122	400.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2WGFK@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158380_k127_3145494_1	1254432.SCE1572_44415	4.73e-120	397.0	COG1404@1|root,COG1404@2|Bacteria,1PEJJ@1224|Proteobacteria,438RE@68525|delta/epsilon subdivisions,2X3YD@28221|Deltaproteobacteria,2YXKA@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158380_k127_3145494_4	1191523.MROS_1419	2.8e-10	65.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_3157282_1	240292.Ava_C0139	2.923e-49	183.0	COG2823@1|root,COG2823@2|Bacteria,1GBV7@1117|Cyanobacteria,1HPUI@1161|Nostocales	1117|Cyanobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158380_k127_3157282_2	1479237.JMLY01000001_gene2639	3.614e-28	121.0	COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,46BCN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_3157282_0	1366050.N234_33695	1.49e-57	209.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158380_k127_3162683_8	525904.Tter_2535	1.446e-48	181.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	narK	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02575,ko:K10850	ko00910,ko02020,map00910,map02020	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	iYO844.BSU37320	MFS_1,PAS_9
SRR25158380_k127_3162683_11	977880.RALTA_A1142	9.06e-21	93.0	COG3615@1|root,COG3615@2|Bacteria,1QVHF@1224|Proteobacteria,2WH8F@28216|Betaproteobacteria,1KE3S@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Protein of unknown function (DUF3565)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3565
SRR25158380_k127_3162683_9	1121422.AUMW01000002_gene2121	9.14e-35	136.0	COG1917@1|root,COG1917@2|Bacteria,1UHAE@1239|Firmicutes,24C81@186801|Clostridia	186801|Clostridia	S	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_3162683_3	266117.Rxyl_1187	1.87e-85	292.0	COG0030@1|root,COG0030@2|Bacteria,2I2II@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158380_k127_3162683_10	1121382.JQKG01000012_gene154	2.191e-34	140.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158380_k127_3162683_4	234267.Acid_2927	5.266e-69	240.0	COG0437@1|root,COG0437@2|Bacteria,3Y4QF@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11
SRR25158380_k127_3162683_0	525904.Tter_2539	4.548e-285	893.0	COG0243@1|root,COG0243@2|Bacteria,2NS49@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasC	-	-	ko:K00372,ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530,M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158380_k127_3162683_1	1254432.SCE1572_23370	2.731e-88	304.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3162683_7	204669.Acid345_1498	2.344e-51	190.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_3162683_2	204669.Acid345_3828	4.506e-86	296.0	COG3303@1|root,COG3303@2|Bacteria,3Y999@57723|Acidobacteria,2JP5G@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SRR25158380_k127_3162683_5	1340493.JNIF01000003_gene1663	1.848e-62	240.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3162683_6	1379698.RBG1_1C00001G0781	2.451e-52	188.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
SRR25158380_k127_3163434_5	671143.DAMO_2141	2.738e-66	232.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158380_k127_3163434_2	251221.35214700	1.436e-112	389.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158380_k127_3163434_4	290398.Csal_3000	4.168e-92	312.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XJ29@135619|Oceanospirillales	135619|Oceanospirillales	P	transporter, permease	oppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158380_k127_3163434_3	1183438.GKIL_1123	8.773e-103	345.0	COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158380_k127_3163434_1	1521187.JPIM01000003_gene2973	1.894e-129	422.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi,374U3@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_3163434_0	251221.35214696	1.213e-134	439.0	COG4608@1|root,COG4608@2|Bacteria,1GR1J@1117|Cyanobacteria	1117|Cyanobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.24	ko:K10823,ko:K10824	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_3163434_15	1203605.HMPREF1531_00733	1.484e-06	59.0	COG2207@1|root,COG4936@1|root,COG2207@2|Bacteria,COG4936@2|Bacteria	2|Bacteria	KT	Sensory domain found in PocR	pocR	-	-	-	-	-	-	-	-	-	-	-	GerE,HTH_18,HTH_AraC,PocR
SRR25158380_k127_3163434_6	1125863.JAFN01000001_gene381	2.055e-60	217.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SRR25158380_k127_3163434_13	487796.Flav2ADRAFT_1527	2.279e-12	81.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158380_k127_3163434_14	1121422.AUMW01000020_gene1706	1.315e-07	59.0	COG1366@1|root,COG1366@2|Bacteria,1VXP2@1239|Firmicutes	1239|Firmicutes	T	STAS domain	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS,STAS_2
SRR25158380_k127_3163434_7	204669.Acid345_2866	3.816e-48	189.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3Y52R@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3163434_16	1283299.AUKG01000001_gene1751	1.887e-05	55.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158380_k127_3163434_11	67352.JODS01000004_gene5983	4.611e-28	130.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_3163434_8	1122939.ATUD01000013_gene874	4.016e-44	179.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158380_k127_3163434_10	883067.HMPREF9237_00448	6.881e-37	158.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4D3JX@85005|Actinomycetales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158380_k127_3163434_9	273068.TTE1967	1.715e-42	177.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,42FRP@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM penicillin-binding protein transpeptidase	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158380_k127_3163434_12	525909.Afer_0092	2.242e-13	80.0	COG1716@1|root,COG1716@2|Bacteria,2HG8X@201174|Actinobacteria,4CN6T@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158380_k127_3168688_1	278963.ATWD01000001_gene3533	8.311e-126	431.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158380_k127_3168688_0	1382359.JIAL01000001_gene2740	0.0	1078.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158380_k127_3168688_2	1128421.JAGA01000002_gene1151	1.901e-55	203.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_3168688_3	857087.Metme_2239	0.0009522	42.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XE02@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158380_k127_3170277_1	861299.J421_5995	8.627e-28	117.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	AAA_16,Abhydrolase_1,PD40,Trans_reg_C
SRR25158380_k127_3170277_2	204669.Acid345_0263	1.675e-10	64.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_3170277_0	234267.Acid_5749	9.889e-174	570.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_3178024_0	1047013.AQSP01000140_gene2536	8.678e-77	269.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3178024_1	1382306.JNIM01000001_gene2082	1.684e-60	217.0	COG1028@1|root,COG1028@2|Bacteria	1382306.JNIM01000001_gene2082|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3178024_2	1267533.KB906740_gene380	1.14e-11	70.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3193030_3	379066.GAU_3308	9.415e-53	190.0	COG2234@1|root,COG2234@2|Bacteria,1ZTDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_3193030_0	251221.35211765	1.08e-201	655.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3193030_2	204669.Acid345_3932	2.133e-96	328.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,3Y49J@57723|Acidobacteria,2JKA2@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
SRR25158380_k127_3193030_1	1500897.JQNA01000002_gene2506	1.106e-102	342.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,1KFK7@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	nirJ	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158380_k127_319732_1	215803.DB30_8826	2.132e-97	320.0	28H95@1|root,2Z7KY@2|Bacteria,1RA0C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
SRR25158380_k127_319732_0	926566.Terro_1174	1.113e-140	491.0	COG1629@1|root,COG4771@2|Bacteria,3Y2M5@57723|Acidobacteria,2JMJB@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_319732_4	1124982.MSI_22010	3.208e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
SRR25158380_k127_319732_3	234267.Acid_4033	3.644e-28	132.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_319732_2	1122138.AQUZ01000019_gene8188	8.543e-92	306.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158380_k127_3200803_1	327079.R9NY71	4.147e-12	73.0	COG0484@1|root,KOG0550@2759|Eukaryota,38CD1@33154|Opisthokonta,3NV1Y@4751|Fungi,3UY69@5204|Basidiomycota,3N4MB@452284|Ustilaginomycotina	4751|Fungi	O	Tetratricopeptide repeat	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077	-	ko:K09527	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SRR25158380_k127_3200803_2	1286093.C266_01060	2.14e-08	60.0	COG2764@1|root,COG2764@2|Bacteria,1N6GB@1224|Proteobacteria,2WEHT@28216|Betaproteobacteria,1K7BG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_3200803_0	1254432.SCE1572_32230	9.18e-117	385.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,42U5B@68525|delta/epsilon subdivisions,2WQVN@28221|Deltaproteobacteria,2YWFF@29|Myxococcales	28221|Deltaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_3209708_0	1173028.ANKO01000129_gene1949	3.661e-77	264.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1HA6X@1150|Oscillatoriales	1117|Cyanobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158380_k127_3209708_1	159087.Daro_1928	1.461e-61	217.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KWIF@206389|Rhodocyclales	206389|Rhodocyclales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158380_k127_3209708_2	639030.JHVA01000001_gene673	1.143e-20	101.0	2A9J8@1|root,30YRM@2|Bacteria,3Y4IZ@57723|Acidobacteria,2JJDB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3210806_0	1267533.KB906735_gene4448	2.854e-185	607.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SRR25158380_k127_3210806_1	903818.KI912268_gene729	7.09e-95	320.0	COG1232@1|root,COG1232@2|Bacteria,3Y3KX@57723|Acidobacteria	57723|Acidobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158380_k127_323207_1	1121440.AUMA01000007_gene1218	5.776e-13	74.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MDCV@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158380_k127_323207_0	1128421.JAGA01000002_gene991	4.199e-170	551.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_3233445_0	234267.Acid_0265	1.641e-137	464.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
SRR25158380_k127_3233445_1	479434.Sthe_0801	1.248e-108	361.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158380_k127_3233445_2	401053.AciPR4_0897	4.525e-86	304.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,3Y2Y4@57723|Acidobacteria,2JI8D@204432|Acidobacteriia	204432|Acidobacteriia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SRR25158380_k127_3233445_3	1329516.JPST01000015_gene737	1.957e-65	233.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,27B1W@186824|Thermoactinomycetaceae	91061|Bacilli	J	RNA 2'-O ribose methyltransferase substrate binding	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158380_k127_3233445_4	118161.KB235922_gene4849	1.35e-60	215.0	COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,3VIQD@52604|Pleurocapsales	1117|Cyanobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158380_k127_3251590_1	379066.GAU_3463	2.467e-55	196.0	2DMXW@1|root,32UAS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3251590_2	1345695.CLSA_c34970	8.992e-28	117.0	COG1671@1|root,COG1671@2|Bacteria,1VC3V@1239|Firmicutes,24N3K@186801|Clostridia,36MDT@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3251590_3	1123242.JH636435_gene1639	1.476e-22	102.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	mutT	-	3.5.4.33,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K11991	ko00230,map00230	-	R01054,R10223	RC00002,RC00477	ko00000,ko00001,ko01000,ko03016,ko03400	-	-	-	NUDIX,PAP2
SRR25158380_k127_3251590_0	1536769.P40081_04290	5.827e-154	490.0	COG1028@1|root,COG1028@2|Bacteria,1TRFB@1239|Firmicutes,4HBF8@91061|Bacilli,26SAT@186822|Paenibacillaceae	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158380_k127_3251590_5	1396141.BATP01000056_gene3167	7.146e-06	49.0	2EGQV@1|root,33AH0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3259730_0	234267.Acid_2218	9.124e-28	123.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158380_k127_3259730_1	521674.Plim_4149	0.0003634	51.0	COG3515@1|root,COG3515@2|Bacteria,2IZ74@203682|Planctomycetes	203682|Planctomycetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3267840_1	404589.Anae109_0714	9.145e-153	500.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158380_k127_3267840_0	234267.Acid_3963	6.244e-244	786.0	COG1629@1|root,COG4771@2|Bacteria,3Y2HF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_3267840_2	234267.Acid_1709	4.469e-13	69.0	28HGI@1|root,2Z7SC@2|Bacteria,3Y3VE@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3286969_1	977880.RALTA_A2413	2.914e-108	353.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1K38F@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158380_k127_3286969_4	426117.M446_1503	3.969e-18	90.0	2ERZG@1|root,33JIK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3286969_3	1150626.PHAMO_80150	6.062e-40	153.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales	204441|Rhodospirillales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158380_k127_3286969_6	1267535.KB906767_gene3216	9.811e-10	72.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158380_k127_3286969_7	1125863.JAFN01000001_gene2618	4.089e-05	53.0	29UFS@1|root,30FSN@2|Bacteria,1RDI2@1224|Proteobacteria,42RWP@68525|delta/epsilon subdivisions,2WNB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3286969_2	1278073.MYSTI_04136	4.241e-54	196.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158380_k127_3286969_5	1267534.KB906759_gene2056	1.451e-16	88.0	28QZS@1|root,2ZDEJ@2|Bacteria,3Y4BV@57723|Acidobacteria	1267534.KB906759_gene2056|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3286969_0	391625.PPSIR1_29036	2.21e-113	382.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158380_k127_3295795_1	867903.ThesuDRAFT_02084	1.483e-124	417.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
SRR25158380_k127_3295795_3	765420.OSCT_2622	9.535e-52	196.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi,37521@32061|Chloroflexia	32061|Chloroflexia	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158380_k127_3295795_2	867903.ThesuDRAFT_02086	5.297e-67	237.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158380_k127_3295795_5	1144275.COCOR_03608	1.451e-34	140.0	COG1309@1|root,COG1309@2|Bacteria,1N9ZB@1224|Proteobacteria,42VC2@68525|delta/epsilon subdivisions,2WRA9@28221|Deltaproteobacteria,2Z2TF@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158380_k127_3295795_0	1267533.KB906734_gene3890	1.125e-163	533.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_3295795_4	401053.AciPR4_0727	2.111e-47	175.0	COG0252@1|root,COG0252@2|Bacteria,3Y8TG@57723|Acidobacteria	57723|Acidobacteria	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158380_k127_3295795_6	1125971.ASJB01000069_gene457	4.284e-11	64.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4E0NK@85010|Pseudonocardiales	201174|Actinobacteria	J	tRNA synthetases class I (E and Q), catalytic domain	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158380_k127_3301234_1	316274.Haur_3380	4.977e-92	306.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158380_k127_3301234_0	240015.ACP_0140	3.863e-140	460.0	COG1109@1|root,COG1109@2|Bacteria,3Y2Y6@57723|Acidobacteria,2JHZU@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_3301234_2	518766.Rmar_2028	1.721e-82	293.0	COG0457@1|root,COG3829@1|root,COG0457@2|Bacteria,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1FIME@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158380_k127_3301234_5	1318628.MARLIPOL_12759	1.602e-05	51.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158380_k127_3301234_6	1318628.MARLIPOL_12759	7.549e-05	48.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158380_k127_3301234_4	1449126.JQKL01000003_gene1796	9.594e-15	83.0	COG4960@1|root,COG4960@2|Bacteria,1UPNE@1239|Firmicutes,24T5Y@186801|Clostridia	186801|Clostridia	OU	PFAM peptidase A24A, prepilin type IV	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
SRR25158380_k127_3301234_3	1500894.JQNN01000001_gene3767	4.127e-56	205.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2VMT6@28216|Betaproteobacteria,4763G@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Flp pilus assembly protein RcpC/CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158380_k127_3305972_1	1128421.JAGA01000003_gene3195	4.74e-110	369.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR25158380_k127_3305972_0	706587.Desti_3751	1.775e-120	400.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MR6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158380_k127_3313201_3	1123368.AUIS01000005_gene414	3.708e-31	125.0	2E36Z@1|root,32Y6R@2|Bacteria,1NCM6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3313201_2	402777.KB235898_gene5158	7.583e-151	488.0	COG0438@1|root,COG0438@2|Bacteria,1G4NH@1117|Cyanobacteria,1H7W9@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158380_k127_3313201_0	1173022.Cri9333_3538	1.656e-205	644.0	COG0438@1|root,COG0562@1|root,COG0438@2|Bacteria,COG0562@2|Bacteria,1G3KR@1117|Cyanobacteria,1HA1P@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM UDP-galactopyranose mutase, C-terminal	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,Glyco_trans_1_4,NAD_binding_8
SRR25158380_k127_3313201_1	179408.Osc7112_5141	1.5e-162	520.0	COG2723@1|root,COG2723@2|Bacteria,1GBD9@1117|Cyanobacteria,1HE57@1150|Oscillatoriales	1117|Cyanobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_33136_0	1121957.ATVL01000010_gene523	4.175e-72	257.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158380_k127_33136_1	1167006.UWK_01809	7.128e-19	94.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2MIM4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipid A core-O-antigen ligase-like enyme	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
SRR25158380_k127_3321384_3	1005048.CFU_3528	1.214e-43	162.0	COG0564@1|root,COG0564@2|Bacteria,1MX5Y@1224|Proteobacteria,2VHUK@28216|Betaproteobacteria,4736Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158380_k127_3321384_4	264201.pc0548	5.819e-34	133.0	COG1186@1|root,COG1186@2|Bacteria,2JH72@204428|Chlamydiae	204428|Chlamydiae	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
SRR25158380_k127_3321384_2	383372.Rcas_4367	3.328e-48	178.0	COG2329@1|root,COG2329@2|Bacteria,2GB5K@200795|Chloroflexi,377CG@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158380_k127_3321384_1	504472.Slin_3334	1.714e-62	223.0	COG2367@1|root,COG2367@2|Bacteria,4NE3C@976|Bacteroidetes,47M1M@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	per1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158380_k127_3321384_5	504472.Slin_3334	5.575e-30	122.0	COG2367@1|root,COG2367@2|Bacteria,4NE3C@976|Bacteroidetes,47M1M@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	per1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158380_k127_3321384_0	452637.Oter_0576	6.397e-64	229.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
SRR25158380_k127_3322965_4	760192.Halhy_4135	3.376e-17	81.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes,1IVCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_3322965_1	1173264.KI913950_gene4603	3.148e-47	172.0	2DNS7@1|root,32YWC@2|Bacteria,1GPZR@1117|Cyanobacteria,1HG4Q@1150|Oscillatoriales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_3322965_0	1382359.JIAL01000001_gene2604	5.306e-157	526.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158380_k127_3322965_2	357808.RoseRS_0380	5.36e-39	147.0	COG4680@1|root,COG4680@2|Bacteria,2GB8T@200795|Chloroflexi,377K5@32061|Chloroflexia	32061|Chloroflexia	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
SRR25158380_k127_3322965_3	105559.Nwat_2947	2.086e-28	115.0	COG5499@1|root,COG5499@2|Bacteria	2|Bacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
SRR25158380_k127_3328356_6	234267.Acid_7167	9.955e-13	72.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRR25158380_k127_3328356_3	504728.K649_00340	7.71e-50	185.0	COG0739@1|root,COG0739@2|Bacteria,1WK9B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158380_k127_3328356_1	1379698.RBG1_1C00001G0290	5.374e-76	284.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
SRR25158380_k127_3328356_4	1121904.ARBP01000010_gene2245	3.523e-40	156.0	COG0454@1|root,COG0456@2|Bacteria,4NURB@976|Bacteroidetes,47SEW@768503|Cytophagia	976|Bacteroidetes	K	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_3328356_2	1122222.AXWR01000004_gene1702	1.615e-74	252.0	COG2080@1|root,COG2080@2|Bacteria,1WK3N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158380_k127_3328356_0	234267.Acid_2226	1.595e-98	330.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158380_k127_3334168_4	1121405.dsmv_3246	6.29e-32	130.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR25158380_k127_3334168_0	886293.Sinac_6462	3.74e-160	510.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158380_k127_3334168_2	1499967.BAYZ01000186_gene3970	1.188e-81	287.0	COG0438@1|root,COG0438@2|Bacteria,2NR2T@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_3334168_1	330214.NIDE3016	6.35e-120	389.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_3334168_3	344747.PM8797T_29887	5.344e-54	197.0	COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158380_k127_3334657_2	335543.Sfum_1625	4.537e-42	166.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SRR25158380_k127_3334657_0	335543.Sfum_1617	5.732e-177	572.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_3334657_1	335543.Sfum_1616	2.774e-80	287.0	COG0457@1|root,COG0457@2|Bacteria,1PFBA@1224|Proteobacteria,43755@68525|delta/epsilon subdivisions,2WQN6@28221|Deltaproteobacteria,2MSBR@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR25158380_k127_334183_4	756272.Plabr_4527	1.226e-72	261.0	COG0673@1|root,COG0673@2|Bacteria,2IXAZ@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158380_k127_334183_6	313596.RB2501_12457	1.943e-26	115.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes,1I3MJ@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158380_k127_334183_5	530564.Psta_0073	1.887e-68	246.0	COG1477@1|root,COG1477@2|Bacteria,2IYYX@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158380_k127_334183_0	1100720.ALKN01000035_gene1001	2.577e-185	591.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
SRR25158380_k127_334183_1	1267535.KB906767_gene2982	2.794e-133	434.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
SRR25158380_k127_334183_3	35754.JNYJ01000037_gene4651	1.092e-81	279.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DH2X@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_334183_2	861299.J421_5594	1.312e-105	349.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_334562_2	760192.Halhy_1512	1.797e-18	94.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IQVH@117747|Sphingobacteriia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
SRR25158380_k127_334562_0	479434.Sthe_2097	9.84e-95	317.0	COG1131@1|root,COG1131@2|Bacteria,2G6HN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_334562_1	1382306.JNIM01000001_gene71	7.115e-30	132.0	COG1668@1|root,COG1668@2|Bacteria,2GA92@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158380_k127_3351347_1	671143.DAMO_2120	1.564e-92	323.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158380_k127_3351347_2	1094715.CM001373_gene1274	4.418e-65	238.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158380_k127_3351347_0	930169.B5T_02691	1.796e-102	345.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria,1XJKP@135619|Oceanospirillales	135619|Oceanospirillales	G	Gluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	Str_synth
SRR25158380_k127_3351347_3	350688.Clos_0030	3.145e-25	115.0	COG1978@1|root,COG1978@2|Bacteria,1UYNY@1239|Firmicutes,24G4U@186801|Clostridia,36E6N@31979|Clostridiaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRR25158380_k127_3351347_4	204669.Acid345_3199	7.154e-11	69.0	2ED8Q@1|root,33759@2|Bacteria,3Y5NT@57723|Acidobacteria,2JJWR@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
SRR25158380_k127_3351347_5	1242864.D187_002036	6.318e-09	62.0	COG1547@1|root,COG1547@2|Bacteria,1P75K@1224|Proteobacteria,432ZJ@68525|delta/epsilon subdivisions,2WXIJ@28221|Deltaproteobacteria,2Z233@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158380_k127_3352710_1	414684.RC1_3136	6.919e-68	241.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2JRAY@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158380_k127_3352710_0	234267.Acid_4808	8.495e-71	250.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
SRR25158380_k127_3352710_2	202955.BBND01000010_gene2405	1.051e-30	126.0	2E30H@1|root,32Y10@2|Bacteria,1N7X0@1224|Proteobacteria,1SSFJ@1236|Gammaproteobacteria,3NP2R@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3357814_0	234267.Acid_3115	1.947e-181	605.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria	57723|Acidobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
SRR25158380_k127_3357814_2	684949.ATTJ01000002_gene106	6.425e-28	118.0	2ECKJ@1|root,33KDJ@2|Bacteria,1WMG2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_3357814_1	330214.NIDE3498	7.984e-74	253.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
SRR25158380_k127_3365702_1	1121011.AUCB01000020_gene3622	7.703e-46	174.0	COG0457@1|root,COG0457@2|Bacteria,4NP60@976|Bacteroidetes,1I5Q6@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
SRR25158380_k127_3365702_0	700598.Niako_3806	2.313e-126	416.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1IQQH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158380_k127_3365702_2	1278073.MYSTI_05299	1.703e-43	171.0	COG0793@1|root,COG0793@2|Bacteria,1R5YM@1224|Proteobacteria	1224|Proteobacteria	M	COG0793 Periplasmic protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,Peptidase_S41,Tricorn_C1
SRR25158380_k127_3388339_3	1121405.dsmv_0774	6.599e-10	69.0	COG0784@1|root,COG0784@2|Bacteria,1RHWK@1224|Proteobacteria,42SCZ@68525|delta/epsilon subdivisions,2WPGH@28221|Deltaproteobacteria,2MK6H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SRR25158380_k127_3388339_1	204669.Acid345_0689	7.204e-131	428.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158380_k127_3388339_2	562970.Btus_1808	6.04e-47	177.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,278BH@186823|Alicyclobacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158380_k127_3388339_0	1267535.KB906767_gene2350	1.389e-204	647.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158380_k127_3410008_1	1122132.AQYH01000005_gene766	9.402e-31	126.0	COG2333@1|root,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria,2U6NT@28211|Alphaproteobacteria,4BH7T@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_3410008_0	391600.ABRU01000056_gene545	1.212e-266	847.0	COG1404@1|root,COG1404@2|Bacteria,1QVJR@1224|Proteobacteria,2TWGK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158380_k127_3414273_0	450851.PHZ_c2461	6.308e-193	612.0	COG5434@1|root,COG5434@2|Bacteria,1MXP8@1224|Proteobacteria,2TVCM@28211|Alphaproteobacteria,2KHU2@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
SRR25158380_k127_3414273_2	745411.B3C1_16129	4.904e-76	262.0	COG2755@1|root,COG2755@2|Bacteria,1MVYS@1224|Proteobacteria,1S0VK@1236|Gammaproteobacteria,1JA8H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	rhgT	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Lipase_GDSL_2
SRR25158380_k127_3414273_3	1198114.AciX9_1168	7.668e-65	230.0	COG2186@1|root,COG2186@2|Bacteria,3Y47U@57723|Acidobacteria,2JI8P@204432|Acidobacteriia	204432|Acidobacteriia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158380_k127_3414273_1	1124780.ANNU01000008_gene2675	6.342e-95	314.0	COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,47K1T@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynBA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRR25158380_k127_3417425_3	1183438.GKIL_1779	1.119e-35	140.0	COG2272@1|root,COG3187@1|root,COG2272@2|Bacteria,COG3187@2|Bacteria,1GA7U@1117|Cyanobacteria	1117|Cyanobacteria	O	META domain	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	META
SRR25158380_k127_3417425_6	1449048.JQKU01000039_gene3754	7.265e-18	86.0	COG2261@1|root,COG2261@2|Bacteria,2HS7B@201174|Actinobacteria,23AWF@1762|Mycobacteriaceae	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158380_k127_3417425_2	1267535.KB906767_gene5149	5.153e-42	159.0	COG1652@1|root,COG1652@2|Bacteria,3Y84E@57723|Acidobacteria	57723|Acidobacteria	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158380_k127_3417425_4	1227268.HMPREF1552_00379	6.807e-30	126.0	COG5403@1|root,COG5403@2|Bacteria,37B87@32066|Fusobacteria	32066|Fusobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158380_k127_3417425_5	1297863.APJF01000038_gene1770	2.829e-22	97.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158380_k127_3417425_7	1123277.KB893206_gene3239	5.272e-05	48.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158380_k127_3417425_0	1121904.ARBP01000007_gene2888	2.005e-247	795.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_3417425_1	1123073.KB899241_gene3142	1.198e-131	424.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RYFT@1236|Gammaproteobacteria,1X97Z@135614|Xanthomonadales	135614|Xanthomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_3433691_5	195250.CM001776_gene2614	1.709e-05	59.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H01T@1129|Synechococcus	1117|Cyanobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_1,TPR_11,TPR_14,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158380_k127_3433691_1	1172179.AUKV01000003_gene7383	4.919e-132	435.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_3433691_2	483219.LILAB_05385	1.437e-38	150.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158380_k127_3433691_4	1267533.KB906736_gene1246	1.62e-13	73.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_3433691_0	886293.Sinac_0207	2.583e-150	484.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
SRR25158380_k127_345376_2	1121920.AUAU01000006_gene316	3.731e-06	55.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000006_gene316|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_345376_1	1121920.AUAU01000004_gene638	5.938e-123	399.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_345376_0	1198114.AciX9_1021	5.536e-158	508.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_3466463_1	697282.Mettu_4062	2.278e-91	306.0	COG2010@1|root,COG2010@2|Bacteria,1MVYK@1224|Proteobacteria,1RQH2@1236|Gammaproteobacteria,1XEU7@135618|Methylococcales	135618|Methylococcales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3466463_4	717606.PaecuDRAFT_2665	4.353e-06	59.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1UJQY@1239|Firmicutes,4ITDJ@91061|Bacilli,270X3@186822|Paenibacillaceae	91061|Bacilli	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_3466463_2	278963.ATWD01000001_gene1278	7.864e-73	257.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158380_k127_3466463_0	243090.RB4667	1.361e-106	362.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3466463_3	1089552.KI911559_gene473	4.286e-30	127.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,2JQ3W@204441|Rhodospirillales	204441|Rhodospirillales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158380_k127_348286_0	1121918.ARWE01000001_gene385	6.107e-185	587.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158380_k127_348286_2	1121936.AUHI01000009_gene211	4.677e-21	99.0	COG0454@1|root,COG0454@2|Bacteria,1V2V3@1239|Firmicutes,4HG5G@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
SRR25158380_k127_348286_1	1123368.AUIS01000006_gene566	5.114e-141	467.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
SRR25158380_k127_348475_4	369723.Strop_0491	4.624e-26	114.0	2A4QM@1|root,30TBX@2|Bacteria,2HU7Y@201174|Actinobacteria,4DGFU@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158380_k127_348475_5	1121920.AUAU01000022_gene2473	4.27e-24	106.0	COG3411@1|root,COG3411@2|Bacteria,3Y54Q@57723|Acidobacteria	57723|Acidobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_348475_6	937777.Deipe_2964	1.033e-19	98.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF4111,NTP_transf_2
SRR25158380_k127_348475_3	247490.KSU1_D0595	2.812e-35	153.0	COG0265@1|root,COG0265@2|Bacteria,2J23K@203682|Planctomycetes	203682|Planctomycetes	OT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
SRR25158380_k127_348475_2	204669.Acid345_0559	1.687e-45	188.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,LolA_like,MacB_PCD
SRR25158380_k127_348475_7	861299.J421_1405	1.354e-16	83.0	2A4E9@1|root,2ZJRI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3492324_0	1123371.ATXH01000019_gene613	2.683e-72	248.0	COG2148@1|root,COG2148@2|Bacteria,2GHZH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158380_k127_3492324_2	1121447.JONL01000001_gene370	2.171e-20	101.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42SP0@68525|delta/epsilon subdivisions,2WNYF@28221|Deltaproteobacteria,2MAXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158380_k127_3492324_1	1123367.C666_03655	5.362e-52	198.0	COG4447@1|root,COG4447@2|Bacteria,1RCCJ@1224|Proteobacteria,2VJGM@28216|Betaproteobacteria,2KVJ7@206389|Rhodocyclales	206389|Rhodocyclales	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158380_k127_3492324_3	1207063.P24_16175	1.368e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales	204441|Rhodospirillales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
SRR25158380_k127_3495076_0	1519464.HY22_09715	1.425e-293	919.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158380_k127_3495076_1	240015.ACP_2217	5.345e-153	497.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_3495076_2	861299.J421_3786	1.339e-20	92.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158380_k127_3498781_5	1123024.AUII01000009_gene1951	4.734e-11	63.0	COG3396@1|root,COG3396@2|Bacteria,2GK2T@201174|Actinobacteria,4DXFS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158380_k127_3498781_4	1379698.RBG1_1C00001G0893	2.492e-32	135.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158380_k127_3498781_1	1123023.JIAI01000002_gene5476	1.229e-83	285.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_3498781_0	1382306.JNIM01000001_gene268	1.616e-106	351.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_3498781_3	439235.Dalk_1739	7.366e-65	230.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,42ZTX@68525|delta/epsilon subdivisions,2WVID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2224	ECH_1
SRR25158380_k127_3498781_2	485913.Krac_2148	4.747e-70	246.0	COG1028@1|root,COG1028@2|Bacteria,2G8CF@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158380_k127_3498781_6	1415779.JOMH01000001_gene124	5.311e-09	68.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158380_k127_3505675_2	234267.Acid_2514	8.327e-21	102.0	2AMVA@1|root,31CS1@2|Bacteria,3Y7GD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3505675_1	861299.J421_5741	7.052e-101	346.0	COG0596@1|root,COG1228@1|root,COG0596@2|Bacteria,COG1228@2|Bacteria,1ZV1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_3505675_0	1521187.JPIM01000022_gene637	1.872e-113	370.0	COG4422@1|root,COG4422@2|Bacteria,2G7TP@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158380_k127_3505675_3	41431.PCC8801_4337	7.406e-07	56.0	COG1028@1|root,COG1028@2|Bacteria	41431.PCC8801_4337|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3508291_2	1385513.N780_06200	3.087e-141	458.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2Y8N8@289201|Pontibacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_3508291_7	1267533.KB906734_gene3891	2.102e-42	166.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158380_k127_3508291_1	667014.Thein_1915	1.409e-147	477.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158380_k127_3508291_4	525904.Tter_1437	5.087e-93	314.0	COG0345@1|root,COG0345@2|Bacteria,2NPIR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158380_k127_3508291_5	1382359.JIAL01000001_gene1139	1.047e-75	259.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria,2JJ5A@204432|Acidobacteriia	204432|Acidobacteriia	F	Formyl transferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158380_k127_3508291_3	240015.ACP_1372	8.327e-127	415.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_3508291_6	1064535.MELS_2091	1.5e-45	179.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H1W6@909932|Negativicutes	909932|Negativicutes	S	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
SRR25158380_k127_3508291_0	1232410.KI421413_gene539	1.996e-168	540.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43RZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Glutamine amidotransferases class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158380_k127_3514441_0	234267.Acid_7826	1.607e-262	826.0	COG1172@1|root,COG1879@1|root,COG1172@2|Bacteria,COG1879@2|Bacteria,3Y5DG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
SRR25158380_k127_3514441_2	1267535.KB906767_gene5458	4.022e-97	328.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
SRR25158380_k127_3514441_1	886293.Sinac_6993	2.056e-192	613.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
SRR25158380_k127_3514441_3	1340493.JNIF01000003_gene3450	4.916e-38	151.0	COG1802@1|root,COG1802@2|Bacteria,3Y849@57723|Acidobacteria	57723|Acidobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158380_k127_3522027_2	530564.Psta_3730	1.203e-40	151.0	COG3779@1|root,COG3779@2|Bacteria,2J1PD@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314
SRR25158380_k127_3522027_4	292563.Cyast_2873	2.662e-05	48.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158380_k127_3522027_0	1416760.AYMS01000040_gene818	1.861e-199	634.0	COG2978@1|root,COG2978@2|Bacteria,4NH64@976|Bacteroidetes,1I0S9@117743|Flavobacteriia	976|Bacteroidetes	H	AbgT putative transporter family	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
SRR25158380_k127_3522027_1	1386089.N865_20480	2.452e-47	183.0	COG2815@1|root,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	-	-	2.7.11.1,3.4.16.4	ko:K03587,ko:K08884,ko:K12132	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01011,ko03036	-	-	-	PASTA
SRR25158380_k127_3522027_3	391612.CY0110_14285	1.829e-09	69.0	2DSP9@1|root,33GWM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3522116_6	215803.DB30_5113	5.012e-08	58.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158380_k127_3522116_4	717231.Flexsi_2276	2.136e-48	178.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	yhbS	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
SRR25158380_k127_3522116_2	582515.KR51_00002240	4.097e-100	332.0	COG0500@1|root,COG2226@2|Bacteria,1G1WF@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158380_k127_3522116_0	861299.J421_5995	1.814e-144	485.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	AAA_16,Abhydrolase_1,PD40,Trans_reg_C
SRR25158380_k127_3522116_5	335543.Sfum_2836	8.883e-47	172.0	COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria	1224|Proteobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
SRR25158380_k127_3522116_3	1173023.KE650771_gene4052	7.408e-51	187.0	COG3265@1|root,COG3265@2|Bacteria	2|Bacteria	G	gluconokinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158380_k127_3522116_1	502025.Hoch_5176	4.482e-140	454.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_3531643_3	1449049.JONW01000007_gene3917	0.0002031	44.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,2U55E@28211|Alphaproteobacteria,2KFVY@204458|Caulobacterales	204458|Caulobacterales	G	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
SRR25158380_k127_3531643_1	639030.JHVA01000001_gene624	8.739e-178	565.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria,2JI9I@204432|Acidobacteriia	204432|Acidobacteriia	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158380_k127_3531643_2	682795.AciX8_3658	1.304e-76	262.0	COG0800@1|root,COG0800@2|Bacteria,3Y4HZ@57723|Acidobacteria,2JKJ9@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158380_k127_3531643_0	1124780.ANNU01000008_gene2675	4.555e-220	693.0	COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,47K1T@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynBA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRR25158380_k127_3533299_0	204669.Acid345_1309	2.254e-126	424.0	COG3383@1|root,COG3383@2|Bacteria,3Y2T6@57723|Acidobacteria,2JIAG@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_10,Fer4_6,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRR25158380_k127_3533299_1	1340493.JNIF01000003_gene1646	1.387e-96	323.0	COG1894@1|root,COG1894@2|Bacteria,3Y2NM@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158380_k127_3535830_7	794903.OPIT5_27065	4.637e-09	65.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158380_k127_3535830_3	204669.Acid345_2486	2.198e-50	187.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_3535830_10	1123255.JHYS01000016_gene1091	0.0004297	55.0	COG2340@1|root,COG3055@1|root,COG4447@1|root,COG2340@2|Bacteria,COG3055@2|Bacteria,COG4447@2|Bacteria,1R14N@1224|Proteobacteria,2WHZ9@28216|Betaproteobacteria,4AIB3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3535830_6	595593.JREV01000009_gene1225	5.5e-17	97.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3535830_2	329726.AM1_G0173	6.046e-122	439.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
SRR25158380_k127_3535830_8	497964.CfE428DRAFT_5991	1.84e-08	59.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3535830_4	1173026.Glo7428_2073	2.675e-46	177.0	COG2931@1|root,COG2931@2|Bacteria,1GB2M@1117|Cyanobacteria	1117|Cyanobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3535830_5	1123261.AXDW01000008_gene934	8.192e-45	164.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,1SDB7@1236|Gammaproteobacteria,1X7ZI@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158380_k127_3535830_1	404589.Anae109_3359	2.944e-140	476.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat
SRR25158380_k127_3535830_9	1239415.CM001837_gene623	0.0002377	46.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,1I2B0@117743|Flavobacteriia,37FN0@326319|Dokdonia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
SRR25158380_k127_3535830_0	1379270.AUXF01000001_gene2147	2.333e-146	477.0	COG0006@1|root,COG0006@2|Bacteria,1ZSZF@142182|Gemmatimonadetes	2|Bacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SRR25158380_k127_3540851_2	234267.Acid_1059	8.587e-31	123.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria	57723|Acidobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158380_k127_3540851_0	234267.Acid_1288	4.346e-134	443.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158380_k127_3540851_3	1295642.H839_13049	8.279e-16	88.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1WE6Q@129337|Geobacillus	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_3540851_4	269797.Mbar_A1824	5.526e-14	81.0	COG5635@1|root,arCOG02967@2157|Archaea,arCOG06747@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NARR@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
SRR25158380_k127_3540851_1	204669.Acid345_0710	1.213e-80	276.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria,2JMAK@204432|Acidobacteriia	204432|Acidobacteriia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
SRR25158380_k127_3542110_1	1250232.JQNJ01000001_gene3312	3.556e-209	659.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_3542110_0	935948.KE386494_gene711	7.74e-291	910.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,42I0Z@68295|Thermoanaerobacterales	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_3554593_0	1382306.JNIM01000001_gene715	1.192e-55	206.0	COG0583@1|root,COG0583@2|Bacteria,2G70X@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein LysR	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158380_k127_3554593_3	1121920.AUAU01000001_gene2234	3.972e-05	53.0	2EPXQ@1|root,33HI8@2|Bacteria,3Y5ZD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3554593_1	1041138.KB890253_gene3884	2.73e-37	153.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VFR7@28211|Alphaproteobacteria,4BNBT@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_3554593_2	1449353.JQMQ01000005_gene1276	1.288e-17	96.0	COG4409@1|root,COG4409@2|Bacteria,2ICIA@201174|Actinobacteria,2NI17@228398|Streptacidiphilus	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158380_k127_3564524_2	932678.THERU_02135	9.41e-39	149.0	COG2346@1|root,COG2346@2|Bacteria,2G5AF@200783|Aquificae	200783|Aquificae	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158380_k127_3564524_0	64471.sync_2679	2.492e-151	491.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_3564524_1	1123073.KB899243_gene666	1.099e-40	153.0	2CX7C@1|root,32T1D@2|Bacteria,1N2N3@1224|Proteobacteria,1S4YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3569722_1	401053.AciPR4_0800	1.404e-78	269.0	COG0606@1|root,COG0606@2|Bacteria,3Y3JA@57723|Acidobacteria,2JI3F@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158380_k127_3569722_0	204669.Acid345_0549	2.155e-81	294.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria,2JHZB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158380_k127_3569722_2	1303518.CCALI_00492	6.769e-14	73.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158380_k127_3579280_5	1094980.Mpsy_1301	2.655e-29	122.0	COG1796@1|root,arCOG00305@2157|Archaea,2XT14@28890|Euryarchaeota,2N90T@224756|Methanomicrobia	224756|Methanomicrobia	L	Helix-hairpin-helix domain	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158380_k127_3579280_3	395964.KE386496_gene1500	9.072e-63	224.0	COG3945@1|root,COG3945@2|Bacteria,1NX3S@1224|Proteobacteria,2U1MQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pfam Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158380_k127_3579280_6	261292.Nit79A3_2553	2.337e-27	118.0	2AZY1@1|root,31S7T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3579280_2	679926.Mpet_2610	3.827e-73	257.0	COG0548@1|root,arCOG00862@2157|Archaea,2XTW9@28890|Euryarchaeota,2N912@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158380_k127_3579280_1	383407.XOC_2751	2.153e-94	320.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158380_k127_3579280_0	518766.Rmar_0947	7.098e-108	363.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_3579280_4	234267.Acid_3542	1.524e-48	176.0	COG0073@1|root,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10,6.1.1.20,6.1.1.6	ko:K01874,ko:K01890,ko:K04566,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03658,R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,B5,tRNA-synt_1f,tRNA-synt_1g,tRNA_bind
SRR25158380_k127_3583488_3	330214.NIDE3009	3.35e-105	367.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
SRR25158380_k127_3583488_1	880073.Calab_0614	2.972e-141	457.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158380_k127_3583488_0	1183438.GKIL_0464	2.461e-166	533.0	COG0677@1|root,COG0677@2|Bacteria,1G4FW@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158380_k127_3583488_2	886293.Sinac_0988	3.187e-126	410.0	COG0531@1|root,COG0531@2|Bacteria,2IX7G@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_3586639_7	1242864.D187_005861	3.608e-59	209.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_3586639_2	861299.J421_1510	1.185e-133	436.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158380_k127_3586639_1	1382359.JIAL01000001_gene3046	8.922e-137	450.0	COG1160@1|root,COG1160@2|Bacteria,3Y3AC@57723|Acidobacteria,2JIAS@204432|Acidobacteriia	204432|Acidobacteriia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158380_k127_3586639_3	398767.Glov_2011	7.842e-127	417.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158380_k127_3586639_9	545695.TREAZ_3376	9.071e-18	86.0	COG1862@1|root,COG1862@2|Bacteria,2J8D6@203691|Spirochaetes	203691|Spirochaetes	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158380_k127_3586639_4	204669.Acid345_0146	4.149e-121	408.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158380_k127_3586639_6	639030.JHVA01000001_gene2636	1.194e-73	261.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158380_k127_3586639_10	401053.AciPR4_4001	1.046e-16	90.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158380_k127_3586639_5	234267.Acid_1281	2.694e-80	275.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR25158380_k127_3586639_8	204669.Acid345_0150	7.139e-24	106.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria,2JJKY@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158380_k127_3586639_12	1192034.CAP_5321	1.292e-11	71.0	COG0848@1|root,COG0848@2|Bacteria,1Q1RQ@1224|Proteobacteria,437EZ@68525|delta/epsilon subdivisions,2X2MA@28221|Deltaproteobacteria,2Z03D@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158380_k127_3586639_11	204669.Acid345_0152	1.301e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria,2JISD@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158380_k127_3586639_0	1382359.JIAL01000001_gene1097	1.672e-176	565.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158380_k127_359161_3	706587.Desti_4874	4.38e-110	369.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MQ68@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158380_k127_359161_8	1123508.JH636440_gene2572	2.703e-13	78.0	COG4319@1|root,COG4319@2|Bacteria,2J3B0@203682|Planctomycetes	203682|Planctomycetes	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158380_k127_359161_0	1382359.JIAL01000001_gene2085	6.14e-170	542.0	COG1228@1|root,COG1228@2|Bacteria,3Y3BK@57723|Acidobacteria,2JKVY@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158380_k127_359161_2	861299.J421_1133	1.979e-141	465.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	gadC	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	iEC042_1314.EC042_1624	AA_permease_2
SRR25158380_k127_359161_5	314254.OA2633_04066	6.75e-38	149.0	COG4319@1|root,COG4319@2|Bacteria,1MZRB@1224|Proteobacteria,2UK7M@28211|Alphaproteobacteria,440N5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158380_k127_359161_1	1173264.KI913949_gene1265	3.109e-145	474.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,1H97S@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158380_k127_359161_4	1173020.Cha6605_2716	1.22e-63	226.0	COG3738@1|root,COG3738@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1287)	yijF	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
SRR25158380_k127_359161_6	649638.Trad_1357	1.192e-28	124.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	PE-PPE,VKG_Carbox
SRR25158380_k127_359161_7	204669.Acid345_1974	8.476e-24	105.0	COG0718@1|root,COG0718@2|Bacteria,3Y5CB@57723|Acidobacteria,2JJRM@204432|Acidobacteriia	204432|Acidobacteriia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158380_k127_3593275_2	102129.Lepto7375DRAFT_2530	6.729e-210	679.0	COG3299@1|root,COG3299@2|Bacteria,1G6U3@1117|Cyanobacteria,1HCMR@1150|Oscillatoriales	1117|Cyanobacteria	T	protein, phage tail-like region	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,Sortilin-Vps10
SRR25158380_k127_3593275_0	485913.Krac_5980	3.308e-253	808.0	COG3299@1|root,COG3299@2|Bacteria,2G79H@200795|Chloroflexi	200795|Chloroflexi	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158380_k127_3593275_7	485913.Krac_5979	1.905e-48	175.0	COG3628@1|root,COG3628@2|Bacteria,2G71T@200795|Chloroflexi	200795|Chloroflexi	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SRR25158380_k127_3593275_6	666685.R2APBS1_0502	1.627e-49	178.0	2CE1N@1|root,32RYY@2|Bacteria,1N23N@1224|Proteobacteria,1S6JJ@1236|Gammaproteobacteria,1XBGY@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3593275_4	330214.NIDE2232	4.696e-93	308.0	COG3501@1|root,COG3501@2|Bacteria	2|Bacteria	T	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SRR25158380_k127_3593275_3	330214.NIDE2231	2.634e-159	510.0	COG3500@1|root,COG3500@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_3593275_8	1215092.PA6_046_00120	8.594e-37	141.0	COG1652@1|root,COG1652@2|Bacteria,1N0XA@1224|Proteobacteria,1SC15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3593275_5	99598.Cal7507_3731	1.685e-92	308.0	2CI52@1|root,2ZC5H@2|Bacteria,1G9UB@1117|Cyanobacteria,1HS9R@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3593275_9	485913.Krac_5971	6.601e-13	74.0	2DT2U@1|root,33IFQ@2|Bacteria,2G9J5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3593275_1	485913.Krac_5970	2.295e-245	771.0	COG0464@1|root,COG0464@2|Bacteria,2G67S@200795|Chloroflexi	200795|Chloroflexi	O	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158380_k127_3597174_0	1179773.BN6_31910	3.168e-86	297.0	COG4447@1|root,COG4447@2|Bacteria,2GMJN@201174|Actinobacteria,4DZFH@85010|Pseudonocardiales	201174|Actinobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158380_k127_3597174_1	404589.Anae109_0216	1.99e-57	204.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158380_k127_3597174_2	204669.Acid345_2577	9.421e-07	61.0	28MS6@1|root,2ZB0K@2|Bacteria,3Y38I@57723|Acidobacteria,2JHU5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3603196_2	411154.GFO_1716	3.545e-31	127.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,1HZVH@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158380_k127_3603196_0	195250.CM001776_gene2702	5.115e-89	302.0	2CCCK@1|root,2Z7UH@2|Bacteria,1GGQS@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3603196_1	1254432.SCE1572_01530	1.056e-48	181.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158380_k127_3603196_3	1300345.LF41_1932	2.066e-19	94.0	2E9RD@1|root,333XM@2|Bacteria,1QUSZ@1224|Proteobacteria,1T2IE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3604176_0	1173028.ANKO01000041_gene3170	6.041e-126	418.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
SRR25158380_k127_3604176_1	1123242.JH636434_gene5469	2.18e-75	257.0	COG2818@1|root,COG2818@2|Bacteria,2IZYU@203682|Planctomycetes	203682|Planctomycetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158380_k127_3604176_3	1210884.HG799465_gene12237	2.486e-45	166.0	COG0662@1|root,COG0662@2|Bacteria,2J42S@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_3604176_6	1158760.AQXP01000034_gene2214	7.636e-18	90.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
SRR25158380_k127_3604176_2	204669.Acid345_2199	8.364e-73	256.0	COG1725@1|root,COG1725@2|Bacteria,3Y8PU@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158380_k127_3604176_5	1340493.JNIF01000003_gene4328	9.277e-29	122.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRR25158380_k127_3604176_4	1191523.MROS_0617	2.732e-44	165.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158380_k127_3606311_0	1345697.M493_12965	1.712e-79	275.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1WF0Q@129337|Geobacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158380_k127_3606311_2	1469607.KK073768_gene509	1.57e-41	170.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HJRR@1161|Nostocales	1117|Cyanobacteria	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
SRR25158380_k127_3606311_1	234267.Acid_2204	4.428e-44	165.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
SRR25158380_k127_3607906_1	388413.ALPR1_08738	7.266e-67	238.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,47KH7@768503|Cytophagia	976|Bacteroidetes	S	Peptidase U62 modulator of DNA gyrase	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158380_k127_3607906_0	234267.Acid_4483	3.844e-67	236.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158380_k127_3607906_2	1047013.AQSP01000131_gene1797	3.455e-45	177.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158380_k127_3607906_3	395961.Cyan7425_4227	1.061e-14	77.0	2AJK9@1|root,31A7A@2|Bacteria,1GF48@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3615291_1	1449126.JQKL01000005_gene899	2.69e-11	74.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,26BWR@186813|unclassified Clostridiales	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_3615291_0	1267535.KB906767_gene3313	5.708e-67	261.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
SRR25158380_k127_3616462_3	306281.AJLK01000163_gene147	2.143e-17	90.0	COG1975@1|root,COG1975@2|Bacteria,1G2SP@1117|Cyanobacteria,1JJMZ@1189|Stigonemataceae	1117|Cyanobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158380_k127_3616462_1	1157490.EL26_22765	2.16e-36	141.0	COG4539@1|root,COG4539@2|Bacteria,1VJFX@1239|Firmicutes,4HQE3@91061|Bacilli,27A12@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158380_k127_3616462_2	768710.DesyoDRAFT_1194	2.239e-21	97.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,2617B@186807|Peptococcaceae	186801|Clostridia	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158380_k127_3616462_0	1121035.AUCH01000005_gene11	4.42e-88	310.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria	1224|Proteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
SRR25158380_k127_3620244_1	1047013.AQSP01000113_gene740	7.158e-94	313.0	COG1472@1|root,COG1472@2|Bacteria,2NNR4@2323|unclassified Bacteria	2|Bacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158380_k127_3620244_2	63577.G9NUE2	4.196e-10	72.0	COG0738@1|root,2QQA7@2759|Eukaryota,38HCE@33154|Opisthokonta,3NWFM@4751|Fungi,3QM7W@4890|Ascomycota,2159Z@147550|Sordariomycetes,3TSEP@5125|Hypocreales,3TWWF@5129|Hypocreaceae	4751|Fungi	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_3620244_0	1403819.BATR01000178_gene5960	9.731e-100	332.0	COG1082@1|root,COG1082@2|Bacteria,46SR1@74201|Verrucomicrobia,2IW0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158380_k127_3620244_3	1226325.HMPREF1548_00622	0.000404	47.0	COG1957@1|root,COG1957@2|Bacteria,1U70Y@1239|Firmicutes,249Q0@186801|Clostridia,36I98@31979|Clostridiaceae	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
SRR25158380_k127_3632028_2	357808.RoseRS_3801	1.875e-64	231.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158380_k127_3632028_0	555088.DealDRAFT_1267	3.156e-70	254.0	COG1721@1|root,COG1721@2|Bacteria,1UYJ3@1239|Firmicutes,24FK2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158380_k127_3632028_1	1267535.KB906767_gene544	2.38e-68	243.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_363404_4	530564.Psta_2919	1.189e-10	67.0	COG5349@1|root,COG5349@2|Bacteria,2J1NF@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158380_k127_363404_0	1254432.SCE1572_31205	1.109e-178	574.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YUKP@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158380_k127_363404_1	246197.MXAN_6665	6.077e-131	430.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158380_k127_363404_2	1379698.RBG1_1C00001G1350	9.275e-93	316.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158380_k127_363404_3	1379698.RBG1_1C00001G1349	2.145e-58	210.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158380_k127_3635307_3	1382359.JIAL01000001_gene1527	7.406e-26	111.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria,2JJNQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158380_k127_3635307_6	743719.PaelaDRAFT_5835	1.206e-05	47.0	COG0454@1|root,COG0456@2|Bacteria,1V433@1239|Firmicutes,4IPX0@91061|Bacilli,27678@186822|Paenibacillaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_3635307_0	195250.CM001776_gene1724	5.773e-78	273.0	COG1357@1|root,COG1357@2|Bacteria,1GIV5@1117|Cyanobacteria,1H37A@1129|Synechococcus	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158380_k127_3635307_4	1198452.Jab_1c09900	3.755e-15	78.0	COG2815@1|root,COG2815@2|Bacteria,1N5XX@1224|Proteobacteria,2VXHF@28216|Betaproteobacteria	28216|Betaproteobacteria	L	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158380_k127_3635307_1	296591.Bpro_3707	2.321e-62	219.0	COG0662@1|root,COG0662@2|Bacteria,1RI2Z@1224|Proteobacteria	1224|Proteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_3635307_2	479433.Caci_7018	4.244e-35	137.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,2GKCA@201174|Actinobacteria	201174|Actinobacteria	O	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158380_k127_3637610_3	886293.Sinac_2397	2.685e-44	166.0	COG1028@1|root,COG1028@2|Bacteria	886293.Sinac_2397|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.3.1.34	ko:K13237	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_3637610_2	1255043.TVNIR_0070	1.813e-60	217.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1WXHX@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158380_k127_3637610_0	671143.DAMO_0013	2.036e-87	295.0	COG0483@1|root,COG0483@2|Bacteria,2NQAS@2323|unclassified Bacteria	2|Bacteria	G	Inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158380_k127_3637610_1	743719.PaelaDRAFT_5826	1.956e-73	254.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,26S4F@186822|Paenibacillaceae	91061|Bacilli	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
SRR25158380_k127_3644664_5	234267.Acid_1765	5.211e-82	284.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_1765|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3644664_1	926566.Terro_2393	2.107e-166	536.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3644664_2	234267.Acid_4169	6.388e-163	524.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158380_k127_3644664_4	56780.SYN_00886	1.574e-90	310.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2MQH8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158380_k127_3644664_6	204669.Acid345_1455	3.5e-75	285.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_3644664_7	234267.Acid_1209	8.668e-66	229.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_3644664_8	204669.Acid345_1693	1.592e-32	132.0	2E81U@1|root,332FW@2|Bacteria,3Y5IC@57723|Acidobacteria,2JJWT@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3644664_3	452637.Oter_2944	6.227e-138	446.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158380_k127_3644664_0	1267533.KB906733_gene3250	2.637e-209	667.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JHXZ@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_3644664_10	861299.J421_1858	7.099e-20	94.0	COG1940@1|root,COG1940@2|Bacteria,1ZV0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158380_k127_365240_5	215803.DB30_2010	1.864e-27	125.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YYU3@29|Myxococcales	28221|Deltaproteobacteria	S	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PQQ_2,VCBS
SRR25158380_k127_365240_0	502025.Hoch_1577	6.293e-214	696.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_365240_2	234267.Acid_7677	5.919e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_365240_3	234267.Acid_0084	1.035e-50	193.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_365240_1	381666.H16_B0311	3.42e-65	229.0	COG0398@1|root,COG0398@2|Bacteria,1N99S@1224|Proteobacteria,2VVYF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_365240_4	1173027.Mic7113_3153	4.647e-34	137.0	COG3807@1|root,COG3807@2|Bacteria,1GDAA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158380_k127_365240_6	1173027.Mic7113_0582	3.465e-22	102.0	COG3409@1|root,COG3409@2|Bacteria,1GR82@1117|Cyanobacteria,1HIA0@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3661799_0	234267.Acid_4393	7.422e-188	619.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3661799_1	234267.Acid_7734	2.72e-24	106.0	COG3823@1|root,COG3823@2|Bacteria,3Y4G6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
SRR25158380_k127_3678866_0	404589.Anae109_4152	2.3e-110	368.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3678866_1	401053.AciPR4_2131	2.809e-34	149.0	COG4191@1|root,COG4191@2|Bacteria,3Y5DB@57723|Acidobacteria,2JJS0@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_3678866_2	323848.Nmul_A1889	1.122e-17	92.0	2DGQ0@1|root,2ZWWC@2|Bacteria,1P87I@1224|Proteobacteria	1224|Proteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158380_k127_3679205_5	269799.Gmet_3216	4.097e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1PEPM@1224|Proteobacteria,42Y8V@68525|delta/epsilon subdivisions,2WU79@28221|Deltaproteobacteria,43TE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8
SRR25158380_k127_3679205_1	530564.Psta_0806	1.47e-150	484.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158380_k127_3679205_3	102232.GLO73106DRAFT_00020540	5.596e-47	176.0	2EGZK@1|root,33ARQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3679205_0	945713.IALB_1501	7.513e-254	796.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158380_k127_3679205_2	1121403.AUCV01000001_gene966	2.928e-128	421.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHW4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158380_k127_3679205_4	247490.KSU1_B0629	4.057e-35	140.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,2J0CA@203682|Planctomycetes	203682|Planctomycetes	C	PFAM nitrogen-fixing NifU domain protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158380_k127_3686232_2	1123508.JH636441_gene3736	4.165e-67	237.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_3686232_0	240016.ABIZ01000001_gene1451	1.102e-159	516.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158380_k127_3686232_1	530564.Psta_4496	1.841e-146	472.0	COG1541@1|root,COG1541@2|Bacteria,2IWUR@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3686232_4	1396141.BATP01000047_gene3884	3.515e-11	69.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia,2IUVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158380_k127_3686232_3	861299.J421_1637	5.077e-31	123.0	2C1P2@1|root,32Y1F@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158380_k127_3688334_4	580327.Tthe_0964	8.368e-31	137.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,249QT@186801|Clostridia	186801|Clostridia	K	transcriptional regulator containing an HTH domain and an	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SRR25158380_k127_3688334_5	204669.Acid345_3571	6.99e-17	94.0	2DC1Z@1|root,2ZCIM@2|Bacteria,3Y4F2@57723|Acidobacteria,2JJ0Y@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158380_k127_3688334_3	1423321.AS29_19075	2.171e-35	141.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158380_k127_3688334_1	204669.Acid345_4746	1.418e-94	318.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158380_k127_3688334_0	760568.Desku_3262	1.08e-94	318.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26011@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158380_k127_3688334_2	485913.Krac_2433	4.284e-60	213.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158380_k127_3707451_2	1267535.KB906767_gene1433	1.125e-32	141.0	COG0859@1|root,COG0859@2|Bacteria,3Y616@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158380_k127_3707451_1	671143.DAMO_0267	3.929e-79	275.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158380_k127_3707451_0	1379698.RBG1_1C00001G0608	1.208e-103	365.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
SRR25158380_k127_3709692_0	1173025.GEI7407_1132	4.568e-149	512.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9
SRR25158380_k127_3709692_4	1382306.JNIM01000001_gene1463	6.986e-83	291.0	COG3875@1|root,COG3875@2|Bacteria,2G8B3@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158380_k127_3709692_1	1123065.ATWL01000011_gene8	7.944e-118	397.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
SRR25158380_k127_3709692_3	926556.Echvi_4034	5.816e-100	335.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	-	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158380_k127_3709692_2	278963.ATWD01000002_gene489	1.69e-112	368.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria,2JHIF@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_3709692_5	926549.KI421517_gene2830	2.33e-69	243.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
SRR25158380_k127_37137_3	1122604.JONR01000045_gene2500	1.329e-116	381.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1SZK5@1236|Gammaproteobacteria,1XCD9@135614|Xanthomonadales	135614|Xanthomonadales	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
SRR25158380_k127_37137_5	448385.sce6538	1.952e-12	71.0	2EPAC@1|root,33GX3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_37137_0	330214.NIDE0577	3.257e-183	585.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
SRR25158380_k127_37137_2	330214.NIDE0577	3.311e-151	482.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
SRR25158380_k127_37137_4	886293.Sinac_7192	1.139e-80	277.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158380_k127_37137_1	118168.MC7420_6877	3.037e-179	569.0	COG1012@1|root,COG1012@2|Bacteria,1G046@1117|Cyanobacteria,1H7Q6@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Aldehyde dehydrogenase	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.gabD,iJN678.gabD	Aldedh
SRR25158380_k127_3715099_1	1250232.JQNJ01000001_gene1366	6.026e-108	357.0	COG1893@1|root,COG1893@2|Bacteria,4NHUI@976|Bacteroidetes,1I7IM@117743|Flavobacteriia	976|Bacteroidetes	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158380_k127_3715099_0	1519464.HY22_11845	1.236e-137	448.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	-	-	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.2,4.4.1.8	ko:K01739,ko:K01760,ko:K01761,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00654,R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02814,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158380_k127_3715099_2	251221.35212369	3.91e-84	299.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	MA20_39390	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158380_k127_3715099_4	1432055.GLUCORHAEAF1_09795	5.296e-17	87.0	2EGX5@1|root,33APA@2|Bacteria,1NHMF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158380_k127_3715099_3	588581.Cpap_4239	8.311e-44	171.0	COG4188@1|root,COG4188@2|Bacteria,1V2UM@1239|Firmicutes,25DA2@186801|Clostridia	186801|Clostridia	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SRR25158380_k127_3715886_3	1229172.JQFA01000002_gene2171	2.799e-25	120.0	COG0006@1|root,COG0006@2|Bacteria,1G0KH@1117|Cyanobacteria,1H7YJ@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158380_k127_3715886_0	1144275.COCOR_04085	2.009e-220	693.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,437U8@68525|delta/epsilon subdivisions,2X33W@28221|Deltaproteobacteria,2YU3R@29|Myxococcales	28221|Deltaproteobacteria	C	Flavin-binding monooxygenase-like	ethA	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8
SRR25158380_k127_3715886_2	1144275.COCOR_04084	2.964e-115	377.0	COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_3715886_1	639030.JHVA01000001_gene2494	4.322e-116	391.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria,2JIM6@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
SRR25158380_k127_3715886_5	1173025.GEI7407_2595	1.033e-16	88.0	COG0789@1|root,COG0789@2|Bacteria,1G66Q@1117|Cyanobacteria,1HBCX@1150|Oscillatoriales	1117|Cyanobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158380_k127_3715886_4	118166.JH976537_gene4552	7.688e-20	93.0	COG2304@1|root,COG2304@2|Bacteria,1G1BE@1117|Cyanobacteria,1HAI7@1150|Oscillatoriales	1117|Cyanobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	Macro,VWA
SRR25158380_k127_37168_6	1267534.KB906760_gene1522	2.291e-34	138.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria,2JHKX@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_37168_0	1183438.GKIL_4354	1.76e-186	609.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_37168_3	251221.35211765	7.328e-150	492.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_37168_5	234267.Acid_2813	3.475e-52	195.0	COG0577@1|root,COG0577@2|Bacteria,3Y6QF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_37168_2	251221.35211765	3.071e-162	540.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_37168_1	1183438.GKIL_4354	4.825e-185	607.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_37168_4	234267.Acid_4154	4.737e-87	301.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_3748274_1	236097.ADG881_1075	4.277e-51	204.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,1RNQ5@1236|Gammaproteobacteria,1XK0D@135619|Oceanospirillales	135619|Oceanospirillales	E	COG2303 Choline dehydrogenase and related flavoproteins	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
SRR25158380_k127_3748274_0	1174528.JH992898_gene2276	5.299e-60	218.0	COG1409@1|root,COG1409@2|Bacteria,1G4KM@1117|Cyanobacteria	1117|Cyanobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158380_k127_3764409_0	518766.Rmar_2202	2.241e-155	503.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJSN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158380_k127_3764409_1	1198114.AciX9_2054	7.806e-117	387.0	COG0189@1|root,COG0189@2|Bacteria,3Y2TT@57723|Acidobacteria,2JM1V@204432|Acidobacteriia	204432|Acidobacteriia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3771419_0	1267535.KB906767_gene3806	3.084e-169	537.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158380_k127_3771419_2	111780.Sta7437_1635	6.991e-103	343.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,3VIAS@52604|Pleurocapsales	1117|Cyanobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158380_k127_3771419_1	1123371.ATXH01000016_gene1818	3.114e-115	387.0	COG2204@1|root,COG2204@2|Bacteria,2GHIR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3771419_4	382464.ABSI01000002_gene4289	1.687e-32	145.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	prsK	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c
SRR25158380_k127_3771419_3	926550.CLDAP_23740	1.901e-68	243.0	COG1218@1|root,COG1218@2|Bacteria	2|Bacteria	P	3'(2'),5'-bisphosphate nucleotidase activity	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158380_k127_3782837_2	234267.Acid_0069	4.084e-25	113.0	COG1391@1|root,COG1391@2|Bacteria,3Y72J@57723|Acidobacteria	57723|Acidobacteria	H	Glutamate-ammonia ligase adenylyltransferase	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158380_k127_3782837_0	234267.Acid_0067	1.926e-212	670.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_3782837_1	1123242.JH636434_gene3359	1.168e-133	434.0	COG1166@1|root,COG1166@2|Bacteria,2IX6P@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SRR25158380_k127_3785864_4	580332.Slit_0873	4.788e-12	72.0	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,2VT8G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
SRR25158380_k127_3785864_2	1484460.JSWG01000015_gene897	1.385e-80	284.0	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
SRR25158380_k127_3785864_3	1379698.RBG1_1C00001G1079	1.897e-80	282.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,FG-GAP,VCBS
SRR25158380_k127_3785864_1	1242864.D187_000036	1.662e-81	280.0	COG2267@1|root,COG2267@2|Bacteria,1R08U@1224|Proteobacteria,42XGE@68525|delta/epsilon subdivisions,2X8N8@28221|Deltaproteobacteria,2Z36G@29|Myxococcales	28221|Deltaproteobacteria	I	Pfam:DUF2305	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158380_k127_3785864_0	1122604.JONR01000025_gene4602	1.049e-97	332.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158380_k127_3787757_0	1246626.BleG1_3609	8.127e-175	584.0	COG1874@1|root,COG1874@2|Bacteria,1UIWU@1239|Firmicutes,4HCA7@91061|Bacilli,1ZC52@1386|Bacillus	91061|Bacilli	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158380_k127_3787757_1	1122604.JONR01000025_gene4602	5.469e-101	353.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158380_k127_3793539_1	439235.Dalk_1937	3.612e-30	129.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2MJUD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158380_k127_3793539_0	204669.Acid345_4201	1.844e-69	239.0	COG1403@1|root,COG1403@2|Bacteria,3Y3PW@57723|Acidobacteria,2JI65@204432|Acidobacteriia	204432|Acidobacteriia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158380_k127_3793539_2	385682.AFSL01000006_gene2309	5.044e-11	64.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,2FUQY@200643|Bacteroidia,3XKF4@558415|Marinilabiliaceae	976|Bacteroidetes	U	mttA/Hcf106 family	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158380_k127_3794741_3	1406840.Q763_15640	4.782e-60	209.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
SRR25158380_k127_3794741_4	1313172.YM304_20690	1.744e-44	167.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158380_k127_3794741_5	1168034.FH5T_07990	4.587e-05	46.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158380_k127_3794741_0	1267535.KB906767_gene4240	2.233e-153	507.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
SRR25158380_k127_3794741_1	1267533.KB906734_gene3796	5.349e-89	309.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158380_k127_3794741_2	234267.Acid_3163	1.371e-71	250.0	COG1858@1|root,COG1858@2|Bacteria,3Y6XX@57723|Acidobacteria	57723|Acidobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3803241_2	1121920.AUAU01000005_gene1038	8.122e-121	404.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_3803241_0	391038.Bphy_2359	1.175e-182	577.0	COG0604@1|root,COG0604@2|Bacteria,1R8NX@1224|Proteobacteria,2W0KY@28216|Betaproteobacteria,1K4PK@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158380_k127_3803241_3	861299.J421_5995	1.285e-98	350.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	AAA_16,Abhydrolase_1,PD40,Trans_reg_C
SRR25158380_k127_3803241_1	1123252.ATZF01000027_gene1612	2.539e-174	573.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
SRR25158380_k127_3803241_4	1380367.JIBC01000010_gene3584	0.0002561	54.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3ZUZ8@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
SRR25158380_k127_3816504_2	1267535.KB906767_gene840	2.158e-44	169.0	COG3142@1|root,COG3142@2|Bacteria	2|Bacteria	P	Participates in the control of copper homeostasis	cutC	GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
SRR25158380_k127_3816504_1	1267535.KB906767_gene1684	8.255e-123	406.0	COG0399@1|root,COG0399@2|Bacteria,3Y7K8@57723|Acidobacteria,2JK8Z@204432|Acidobacteriia	57723|Acidobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158380_k127_3816504_0	1267535.KB906767_gene1683	1.621e-135	444.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim,Prenyltrans
SRR25158380_k127_3816504_3	1158294.JOMI01000001_gene1756	0.0008495	52.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRR25158380_k127_3822453_1	700598.Niako_6457	1.852e-63	222.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_3822453_0	204669.Acid345_4190	1.434e-79	300.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_382720_1	378806.STAUR_7749	2.566e-29	126.0	COG0739@1|root,COG0739@2|Bacteria,1NJ25@1224|Proteobacteria	1224|Proteobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_382720_2	234267.Acid_5036	1.886e-25	123.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
SRR25158380_k127_382720_0	502025.Hoch_1577	6.577e-163	538.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_3843849_3	234267.Acid_7925	7.295e-30	124.0	COG3832@1|root,COG3832@2|Bacteria,3Y94H@57723|Acidobacteria	57723|Acidobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3843849_2	1382359.JIAL01000001_gene2266	1.103e-34	147.0	COG0265@1|root,COG0265@2|Bacteria,3Y7GN@57723|Acidobacteria,2JM8V@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3843849_0	1150399.AQYK01000001_gene1856	3.181e-133	435.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4FM9S@85023|Microbacteriaceae	201174|Actinobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158380_k127_3843849_1	1432055.GLUCORHAEAF1_09795	9.939e-36	139.0	2EGX5@1|root,33APA@2|Bacteria,1NHMF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158380_k127_3843849_4	1031711.RSPO_c00296	2.173e-11	66.0	COG0457@1|root,COG0457@2|Bacteria	1031711.RSPO_c00296|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3844572_2	401053.AciPR4_2301	7.129e-23	104.0	COG2755@1|root,COG2755@2|Bacteria,3Y2YQ@57723|Acidobacteria,2JHNK@204432|Acidobacteriia	204432|Acidobacteriia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158380_k127_3844572_1	234267.Acid_7677	2.806e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_3844572_0	234267.Acid_6834	6.567e-100	349.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_3845475_1	247490.KSU1_C0714	1.646e-181	599.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
SRR25158380_k127_3845475_0	243231.GSU1252	0.0	1074.0	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria	1224|Proteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_384744_0	1122604.JONR01000059_gene1132	1.196e-193	626.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,1SZ73@1236|Gammaproteobacteria,1X33T@135614|Xanthomonadales	135614|Xanthomonadales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158380_k127_3868700_0	1340493.JNIF01000003_gene1504	6.532e-131	424.0	COG1131@1|root,COG1131@2|Bacteria,3Y4YH@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_3868700_3	1123242.JH636434_gene4387	1.319e-06	59.0	COG1277@1|root,COG1277@2|Bacteria,2J0ZV@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158380_k127_3868700_1	234267.Acid_7689	1.068e-129	422.0	COG1131@1|root,COG1131@2|Bacteria,3Y6U6@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_3868700_2	234267.Acid_7690	2.415e-64	236.0	COG3712@1|root,COG3712@2|Bacteria,3Y772@57723|Acidobacteria	57723|Acidobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158380_k127_3871383_1	575540.Isop_2732	3.402e-67	244.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_3
SRR25158380_k127_3871383_0	575540.Isop_2733	2.03e-83	288.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	ecsA_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158380_k127_3873362_1	1183438.GKIL_2917	2.949e-17	83.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_3873362_2	1121896.JMLU01000029_gene2952	2.504e-14	87.0	COG0463@1|root,COG0463@2|Bacteria,4PMI9@976|Bacteroidetes,1IJU1@117743|Flavobacteriia,2NTKG@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_3873362_3	1240349.ANGC01000001_gene2575	1.722e-07	65.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_3873362_0	1449346.JQMO01000003_gene5945	3.801e-46	191.0	COG1216@1|root,COG1216@2|Bacteria,2I9UY@201174|Actinobacteria,2M5HW@2063|Kitasatospora	201174|Actinobacteria	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158380_k127_3884025_9	994479.GL877878_gene707	4.142e-20	93.0	COG1651@1|root,COG1651@2|Bacteria,2GM6C@201174|Actinobacteria,4E3T8@85010|Pseudonocardiales	201174|Actinobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_3884025_10	671143.DAMO_1384	3.38e-09	64.0	COG4243@1|root,COG4243@2|Bacteria,2NQGE@2323|unclassified Bacteria	2|Bacteria	S	Vitamin k epoxide reductase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158380_k127_3884025_4	530564.Psta_0515	2.364e-84	285.0	COG2041@1|root,COG2041@2|Bacteria,2IYS5@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase, molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158380_k127_3884025_3	1278073.MYSTI_06568	1.087e-114	386.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales	28221|Deltaproteobacteria	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
SRR25158380_k127_3884025_0	1379270.AUXF01000004_gene3297	1.268e-191	609.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_3884025_1	861299.J421_2513	6.446e-139	454.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158380_k127_3884025_2	1173027.Mic7113_4893	9.984e-130	453.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158380_k127_3884025_5	134676.ACPL_6319	1.581e-76	264.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4DF5S@85008|Micromonosporales	201174|Actinobacteria	S	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158380_k127_3884025_8	1379270.AUXF01000001_gene2573	7.145e-24	106.0	COG0824@1|root,COG0824@2|Bacteria,1ZV5K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158380_k127_3884025_6	383372.Rcas_1067	2.302e-70	245.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158380_k127_3884025_7	234267.Acid_4250	1.767e-49	192.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
SRR25158380_k127_3885303_0	1047013.AQSP01000126_gene2744	3.025e-63	241.0	COG3345@1|root,COG3345@2|Bacteria,2NRWP@2323|unclassified Bacteria	2|Bacteria	G	Melibiase	rafA	GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
SRR25158380_k127_3889241_0	234267.Acid_1869	1.975e-138	448.0	COG0031@1|root,COG0031@2|Bacteria,3Y71B@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_3889241_1	555779.Dthio_PD1826	8.158e-08	60.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MC4D@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158380_k127_3900361_2	861299.J421_0074	1.424e-87	296.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158380_k127_3900361_3	1192034.CAP_3992	1.487e-75	256.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_3900361_5	103690.17135028	1.091e-28	121.0	COG1572@1|root,COG1572@2|Bacteria,1GBQN@1117|Cyanobacteria,1HN4C@1161|Nostocales	1117|Cyanobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3900361_1	1045855.DSC_03395	3.369e-169	554.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158380_k127_3900361_0	118163.Ple7327_1920	6.574e-187	595.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,3VJCM@52604|Pleurocapsales	1117|Cyanobacteria	E	WD40-like Beta Propeller Repeat	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_3908514_0	1232410.KI421422_gene2032	9.555e-293	919.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158380_k127_3908514_1	555088.DealDRAFT_0228	1.142e-100	343.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,42KD6@68298|Syntrophomonadaceae	186801|Clostridia	C	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
SRR25158380_k127_3912203_0	945713.IALB_2579	3e-206	659.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	bglX	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_3912203_2	1382359.JIAL01000001_gene1850	3.148e-47	175.0	2ADDN@1|root,3133D@2|Bacteria,3Y4SX@57723|Acidobacteria,2JJFB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3912203_1	215803.DB30_1517	6.346e-73	258.0	COG2204@1|root,COG3292@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y
SRR25158380_k127_392030_0	926550.CLDAP_00560	0.0	1124.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
SRR25158380_k127_392056_1	518766.Rmar_1585	4.014e-11	74.0	COG1493@1|root,COG1493@2|Bacteria,4P7YQ@976|Bacteroidetes	976|Bacteroidetes	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_392056_0	1499967.BAYZ01000030_gene1170	1.064e-33	143.0	COG0535@1|root,COG0535@2|Bacteria,2NRPX@2323|unclassified Bacteria	2|Bacteria	S	Radical SAM superfamily	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158380_k127_392056_4	903814.ELI_1072	0.0001056	49.0	2E5V7@1|root,330JA@2|Bacteria,1VFNT@1239|Firmicutes,24RD2@186801|Clostridia,25ZD1@186806|Eubacteriaceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158380_k127_392056_3	1449346.JQMO01000002_gene1125	2.214e-07	63.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria,2M390@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158380_k127_3928780_5	378806.STAUR_0306	4.667e-27	113.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria,2YX6B@29|Myxococcales	28221|Deltaproteobacteria	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158380_k127_3928780_2	522772.Dacet_1170	7.821e-68	237.0	COG2316@1|root,COG2316@2|Bacteria,2GFCZ@200930|Deferribacteres	200930|Deferribacteres	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158380_k127_3928780_6	1382359.JIAL01000001_gene2418	1.041e-22	112.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158380_k127_3928780_3	1232410.KI421412_gene412	2.473e-49	186.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158380_k127_3928780_0	1232410.KI421412_gene411	1.708e-116	389.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158380_k127_3928780_1	1268237.G114_11295	1.399e-86	295.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1Y42T@135624|Aeromonadales	135624|Aeromonadales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158380_k127_3928780_4	247490.KSU1_B0623	3.032e-48	179.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2IXP2@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158380_k127_3932763_0	1379698.RBG1_1C00001G0780	1.084e-138	448.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
SRR25158380_k127_3932763_1	671143.DAMO_0822	1.706e-130	430.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
SRR25158380_k127_3932763_2	1121456.ATVA01000011_gene1355	1.64e-05	57.0	COG0484@1|root,COG0484@2|Bacteria,1R72H@1224|Proteobacteria,42NCE@68525|delta/epsilon subdivisions,2WKDN@28221|Deltaproteobacteria,2M9A6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	hmcA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
SRR25158380_k127_3939507_3	1123242.JH636434_gene5302	3.117e-16	81.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3939507_1	1123242.JH636434_gene5497	9.529e-200	643.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_3939507_0	1121920.AUAU01000018_gene1783	0.0	1152.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_3939507_2	1005048.CFU_2490	6.505e-60	210.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2VS3X@28216|Betaproteobacteria,474FC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158380_k127_3940735_2	1122963.AUHB01000010_gene1507	2.989e-29	121.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria,36YV8@31993|Methylocystaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158380_k127_3940735_1	84531.JMTZ01000045_gene1034	4.112e-52	190.0	2D579@1|root,32TID@2|Bacteria,1RH2N@1224|Proteobacteria,1SIU3@1236|Gammaproteobacteria,1X78M@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3940735_0	211114.JOEF01000059_gene2720	3.425e-151	492.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4E1JQ@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158380_k127_3947186_5	204669.Acid345_2810	5.277e-28	117.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158380_k127_3947186_3	316067.Geob_3433	2.271e-57	205.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,42TFN@68525|delta/epsilon subdivisions,2WP7M@28221|Deltaproteobacteria,43SNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158380_k127_3947186_4	665571.STHERM_c07040	9.834e-40	165.0	COG1488@1|root,COG1488@2|Bacteria,2J5IF@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158380_k127_3947186_1	983545.Glaag_0984	1.277e-116	379.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,4643V@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Class II aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158380_k127_3947186_0	1254432.SCE1572_17235	0.0	1355.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158380_k127_3947186_2	1254432.SCE1572_17230	4.985e-99	338.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158380_k127_3951119_6	768704.Desmer_2682	0.0001063	47.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,261FY@186807|Peptococcaceae	186801|Clostridia	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158380_k127_3951119_5	880072.Desac_2486	2.91e-26	122.0	COG4733@1|root,COG4733@2|Bacteria,1NA5J@1224|Proteobacteria,42WEQ@68525|delta/epsilon subdivisions,2WSA0@28221|Deltaproteobacteria,2MSD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3951119_0	234267.Acid_7339	5.518e-202	639.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria	57723|Acidobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158380_k127_3951119_1	234267.Acid_7340	1.091e-72	248.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria	57723|Acidobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158380_k127_3951119_3	935948.KE386494_gene753	1.058e-48	184.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,42GIT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158380_k127_3951119_2	1191523.MROS_1806	9.516e-69	241.0	COG1028@1|root,COG1028@2|Bacteria	1191523.MROS_1806|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158380_k127_3951119_4	589865.DaAHT2_0978	3.008e-37	147.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MI37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158380_k127_395327_3	264462.Bd3480	1.026e-92	308.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,42P6R@68525|delta/epsilon subdivisions,2MSMN@213481|Bdellovibrionales,2WKXS@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158380_k127_395327_9	41431.PCC8801_3515	1.592e-15	79.0	COG1598@1|root,COG1598@2|Bacteria,1G8RN@1117|Cyanobacteria,3KIM2@43988|Cyanothece	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158380_k127_395327_0	1379698.RBG1_1C00001G0607	6.385e-125	434.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158380_k127_395327_5	234267.Acid_7677	4.118e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_395327_4	1120949.KB903303_gene6814	4.162e-78	276.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158380_k127_395327_1	1340493.JNIF01000003_gene4050	3.52e-124	411.0	COG1473@1|root,COG1473@2|Bacteria,3Y40E@57723|Acidobacteria	2|Bacteria	S	Peptidase dimerisation domain	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_395327_2	240016.ABIZ01000001_gene48	3.57e-105	355.0	COG2271@1|root,COG2271@2|Bacteria,46UJ4@74201|Verrucomicrobia,2IWFQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_395327_11	864051.BurJ1DRAFT_0122	3.28e-09	64.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria	1224|Proteobacteria	T	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158380_k127_395327_7	102232.GLO73106DRAFT_00029200	3.627e-24	111.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1G7AX@1117|Cyanobacteria	1117|Cyanobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	-	-	-	-	-	-	-	-	-	YscW
SRR25158380_k127_395327_8	211165.AJLN01000085_gene1633	3.627e-24	111.0	COG3187@1|root,COG3187@2|Bacteria,1G7C2@1117|Cyanobacteria	1117|Cyanobacteria	O	LppP/LprE lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_21,META
SRR25158380_k127_396422_1	234267.Acid_1183	3.611e-213	681.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y6RM@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
SRR25158380_k127_396422_0	1267534.KB906754_gene2613	3.268e-227	712.0	COG2723@1|root,COG2723@2|Bacteria,3Y484@57723|Acidobacteria,2JIKZ@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM glycoside hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158380_k127_396422_2	1288963.ADIS_1999	7.316e-25	115.0	COG1957@1|root,COG1957@2|Bacteria,4NJ4J@976|Bacteroidetes,47KD9@768503|Cytophagia	976|Bacteroidetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
SRR25158380_k127_3971108_1	1123242.JH636434_gene3641	6.531e-99	327.0	COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158380_k127_3971108_0	204669.Acid345_2996	3.425e-115	379.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158380_k127_3971108_2	886293.Sinac_3660	4.536e-76	265.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158380_k127_3971108_3	1128421.JAGA01000003_gene2874	1.265e-57	207.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3971838_1	344747.PM8797T_07337	8.863e-49	181.0	COG0591@1|root,COG0591@2|Bacteria,2IXNM@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158380_k127_3971838_0	1444309.JAQG01000073_gene255	9.799e-84	287.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,26QZT@186822|Paenibacillaceae	91061|Bacilli	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158380_k127_3971838_3	1408254.T458_20970	1.849e-36	151.0	COG2971@1|root,COG2971@2|Bacteria,1V87Z@1239|Firmicutes,4HJ58@91061|Bacilli,276KV@186822|Paenibacillaceae	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158380_k127_3971838_2	572477.Alvin_1364	3.257e-40	161.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WWR6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator, LysR	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158380_k127_3976532_0	234267.Acid_6834	5.506e-47	175.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_3976532_2	665571.STHERM_c03710	5.178e-10	66.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Peripla_BP_3,Response_reg,Y_Y_Y
SRR25158380_k127_3976532_3	489825.LYNGBM3L_53970	7.154e-10	66.0	2EHUH@1|root,33BK4@2|Bacteria,1GG8C@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3976532_1	1267534.KB906755_gene4470	1.12e-25	121.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y7SS@57723|Acidobacteria,2JMXC@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158380_k127_3978010_2	1267534.KB906758_gene2365	7.53e-43	158.0	2DKVG@1|root,30GRY@2|Bacteria,3Y4H8@57723|Acidobacteria,2JJAT@204432|Acidobacteriia	204432|Acidobacteriia	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
SRR25158380_k127_3978010_1	1267534.KB906755_gene4673	3.901e-117	387.0	COG2273@1|root,COG2273@2|Bacteria,3Y6GF@57723|Acidobacteria,2JKH1@204432|Acidobacteriia	204432|Acidobacteriia	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3978010_0	1267534.KB906755_gene4687	1.97e-292	924.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y6BT@57723|Acidobacteria,2JKYZ@204432|Acidobacteriia	204432|Acidobacteriia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158380_k127_3987619_0	251221.35213742	5.607e-108	364.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_3987619_1	179408.Osc7112_6220	3.651e-61	224.0	COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
SRR25158380_k127_3987619_2	1403819.BATR01000066_gene1994	2.437e-10	69.0	2EP8I@1|root,33GV9@2|Bacteria,46VKV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3987714_1	251221.35211983	5.023e-73	256.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3987714_0	1189620.AJXL01000035_gene667	4.57e-106	352.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1I0GM@117743|Flavobacteriia,2NUEW@237|Flavobacterium	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_3987714_3	530564.Psta_4075	2.465e-38	146.0	COG3631@1|root,COG3631@2|Bacteria,2J39A@203682|Planctomycetes	203682|Planctomycetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3987714_2	1406840.Q763_09495	3.135e-44	164.0	COG1733@1|root,COG1733@2|Bacteria,4NNTG@976|Bacteroidetes,1I2BE@117743|Flavobacteriia,2NWJW@237|Flavobacterium	976|Bacteroidetes	K	HxlR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_3988713_1	221288.JH992901_gene3767	1.252e-20	106.0	COG0823@1|root,COG0823@2|Bacteria,1G8I3@1117|Cyanobacteria	1117|Cyanobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158380_k127_3988713_0	1242864.D187_010108	3.764e-43	175.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
SRR25158380_k127_3993045_1	204669.Acid345_4390	6.133e-142	485.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_3993045_2	234267.Acid_5780	9.063e-116	414.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
SRR25158380_k127_3993045_3	1183438.GKIL_3324	1.752e-83	293.0	COG0477@1|root,COG2814@2|Bacteria,1G2N2@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158380_k127_3993045_0	1499967.BAYZ01000173_gene5813	3.129e-158	525.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
SRR25158380_k127_399393_1	530564.Psta_3462	3.757e-129	421.0	COG0667@1|root,COG0667@2|Bacteria,2IYAG@203682|Planctomycetes	203682|Planctomycetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_399393_0	118168.MC7420_356	0.0	1047.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158380_k127_4021728_3	768710.DesyoDRAFT_1324	5.942e-19	101.0	COG1316@1|root,COG2247@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG5492@1|root,COG1316@2|Bacteria,COG2247@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1UKQV@1239|Firmicutes	1239|Firmicutes	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
SRR25158380_k127_4021728_1	1009370.ALO_10494	5.167e-22	113.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4H20H@909932|Negativicutes	909932|Negativicutes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158380_k127_4021728_0	864051.BurJ1DRAFT_2047	5.036e-93	337.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VWI8@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158380_k127_4021728_2	710696.Intca_2240	7.004e-20	101.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4FFWK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158380_k127_4023785_2	234267.Acid_0471	3.749e-29	121.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SRR25158380_k127_4023785_3	1380390.JIAT01000010_gene4167	1.665e-09	70.0	COG0666@1|root,COG0666@2|Bacteria,2HPZA@201174|Actinobacteria,4CRER@84995|Rubrobacteria	84995|Rubrobacteria	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SRR25158380_k127_4023785_0	204669.Acid345_1052	3.296e-191	625.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_4033581_2	861299.J421_0340	6.413e-12	76.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158380_k127_4033581_3	204669.Acid345_1037	5.301e-08	63.0	COG3595@1|root,COG3595@2|Bacteria,3Y97I@57723|Acidobacteria,2JNRB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4033581_4	1047013.AQSP01000139_gene2326	6.486e-05	53.0	COG5660@1|root,COG5660@2|Bacteria	2|Bacteria	S	Putative zinc-finger	sigC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
SRR25158380_k127_4033581_0	1198114.AciX9_2646	2.866e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4033581_1	204669.Acid345_3543	1.011e-59	209.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
SRR25158380_k127_4037045_4	247490.KSU1_C0173	2.356e-70	250.0	COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158380_k127_4037045_6	1123073.KB899242_gene1520	2.739e-26	116.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	4.4.1.3,5.3.3.19	ko:K16953,ko:K19547	ko00920,ko01130,map00920,map01130	M00787	R02574	RC00747,RC00748	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Arg_Hydrox,Cupin_1,Cupin_2
SRR25158380_k127_4037045_0	204669.Acid345_3543	2.203e-199	634.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
SRR25158380_k127_4037045_3	204669.Acid345_1052	1.691e-117	411.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_4037045_5	1183438.GKIL_3396	1.729e-34	139.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158380_k127_4037045_12	1041139.KB902724_gene4012	0.0003677	49.0	COG2133@1|root,COG2133@2|Bacteria,1Q7M3@1224|Proteobacteria,2VDSE@28211|Alphaproteobacteria,4BC34@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4037045_8	234267.Acid_4494	3.999e-19	89.0	COG1595@1|root,COG1595@2|Bacteria,3Y7YB@57723|Acidobacteria	2|Bacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158380_k127_4037045_10	234267.Acid_1208	3.387e-13	76.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
SRR25158380_k127_4037045_2	1267534.KB906756_gene140	5.058e-131	444.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SRR25158380_k127_4037045_7	1267534.KB906756_gene350	3.5e-20	95.0	COG0457@1|root,COG3710@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8,Trans_reg_C
SRR25158380_k127_4037045_9	1382359.JIAL01000001_gene2547	7.413e-16	90.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158380_k127_4037045_1	756499.Desde_2885	1.356e-142	462.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158380_k127_4040905_0	1191523.MROS_1166	1.85e-145	477.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158380_k127_4040905_1	941449.dsx2_0833	3.168e-115	383.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QV3@68525|delta/epsilon subdivisions,2WMT2@28221|Deltaproteobacteria,2MA5X@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
SRR25158380_k127_4040905_2	1191523.MROS_0679	7.939e-27	115.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_4042643_0	240016.ABIZ01000001_gene5682	3.769e-98	325.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158380_k127_4042643_1	485913.Krac_5261	5.79e-55	203.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	rhaR	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158380_k127_4042643_2	234267.Acid_5342	9.747e-49	188.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053,ko:K13735	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05100,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map05100	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	NHL,SGL
SRR25158380_k127_4045130_4	1128421.JAGA01000004_gene2519	7.157e-78	264.0	COG0693@1|root,COG0693@2|Bacteria,2NPFP@2323|unclassified Bacteria	2|Bacteria	S	DJ-1/PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158380_k127_4045130_0	861299.J421_1661	6.965e-187	595.0	COG0534@1|root,COG0534@2|Bacteria,1ZUGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158380_k127_4045130_5	335543.Sfum_3325	5.125e-41	154.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2MQ7Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
SRR25158380_k127_4045130_2	234267.Acid_5786	6.413e-145	474.0	COG0265@1|root,COG0265@2|Bacteria,3Y2WB@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_4045130_3	1144275.COCOR_03677	3.64e-97	345.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3
SRR25158380_k127_4045130_1	1297742.A176_00264	5.315e-171	547.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z2X4@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_4045130_7	28229.ND2E_3304	0.0007869	50.0	2ECDG@1|root,336BQ@2|Bacteria,1NZ7Z@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158380_k127_4063419_2	1267533.KB906742_gene676	1.712e-07	53.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria,2JM2J@204432|Acidobacteriia	204432|Acidobacteriia	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
SRR25158380_k127_4063419_0	330214.NIDE3498	5.504e-206	661.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
SRR25158380_k127_4064720_3	479432.Sros_6897	5.123e-10	68.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR25158380_k127_4064720_1	1123368.AUIS01000020_gene1108	3.596e-35	140.0	COG5592@1|root,COG5592@2|Bacteria,1RGUY@1224|Proteobacteria,1S5V6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hemerythrin hhe cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158380_k127_4064720_0	102129.Lepto7375DRAFT_8055	6.891e-89	299.0	28XBK@1|root,2ZJ9G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_406624_0	886293.Sinac_1156	3.508e-201	655.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SRR25158380_k127_406624_2	1267534.KB906755_gene4692	2.005e-76	278.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_406624_1	1267533.KB906733_gene2988	1.681e-80	274.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_4072966_0	234267.Acid_7425	9.074e-99	331.0	COG0766@1|root,COG0766@2|Bacteria,3Y2IC@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158380_k127_4072966_1	861299.J421_0340	1.448e-70	250.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158380_k127_4072966_2	1337093.MBE-LCI_0934	5.172e-60	218.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,2P8QG@245186|Loktanella	28211|Alphaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158380_k127_4076126_2	46429.BV95_00598	3.654e-10	71.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,2UG7N@28211|Alphaproteobacteria,2K47E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4076126_1	656024.FsymDg_0829	1.58e-28	128.0	COG3420@1|root,COG3420@2|Bacteria,2GPK6@201174|Actinobacteria	201174|Actinobacteria	P	TIR domain	-	-	-	ko:K10297	-	-	-	-	ko00000,ko04121	-	-	-	Beta_helix,TIR_2
SRR25158380_k127_4076126_0	1120965.AUBV01000004_gene739	3.868e-219	685.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_4080721_3	861299.J421_6341	3.512e-39	152.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_4080721_2	316274.Haur_2022	5.577e-43	171.0	COG4447@1|root,COG4447@2|Bacteria,2G9IJ@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4080721_1	1502852.FG94_00099	5.418e-78	282.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_4080721_0	219305.MCAG_01893	6.448e-91	317.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4D9MD@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_4081393_5	208439.AJAP_19275	0.0001086	53.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_12
SRR25158380_k127_4081393_0	1128421.JAGA01000002_gene991	2.084e-173	560.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_4081393_3	1121441.AUCX01000012_gene3308	8.58e-11	68.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MDCV@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158380_k127_4081393_2	1047013.AQSP01000099_gene1495	1.486e-39	160.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158380_k127_4081393_1	234267.Acid_1509	1.559e-148	487.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4081393_4	1198114.AciX9_1878	1.129e-10	65.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4084921_3	102125.Xen7305DRAFT_00018750	4.292e-60	216.0	28N7G@1|root,2ZBC5@2|Bacteria,1G9E1@1117|Cyanobacteria,3VM0A@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4084921_0	65093.PCC7418_2806	3.804e-124	409.0	COG0438@1|root,COG0438@2|Bacteria,1G0PD@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158380_k127_4084921_1	65093.PCC7418_2805	1.881e-93	316.0	COG1216@1|root,COG1216@2|Bacteria,1GB4Y@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_4084921_5	46234.ANA_C10376	1.428e-33	141.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	ubiG	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158380_k127_4084921_6	997884.HMPREF1068_01419	4.327e-12	78.0	COG0438@1|root,COG0438@2|Bacteria,4NSRB@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158380_k127_4084921_4	107636.JQNK01000002_gene405	4.003e-41	165.0	COG1216@1|root,COG1216@2|Bacteria,1NK8J@1224|Proteobacteria,2UKYQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_4084921_2	1173027.Mic7113_4444	1.69e-80	275.0	COG4122@1|root,COG4122@2|Bacteria,1G4B7@1117|Cyanobacteria,1HD9H@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158380_k127_4098582_0	234267.Acid_3931	0.0	1364.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158380_k127_4098582_1	710111.FraQA3DRAFT_6069	2.145e-42	163.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_4098582_2	1205680.CAKO01000038_gene1693	6.232e-19	97.0	COG0526@1|root,COG0526@2|Bacteria,1P67Q@1224|Proteobacteria	1224|Proteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4099251_0	644283.Micau_0432	6.612e-12	71.0	2EJSZ@1|root,33DHM@2|Bacteria,2I643@201174|Actinobacteria,4DMSQ@85008|Micromonosporales	201174|Actinobacteria	S	VHL beta domain	-	-	-	-	-	-	-	-	-	-	-	-	VHL
SRR25158380_k127_4107581_1	1267534.KB906755_gene4498	2.174e-100	344.0	COG0145@1|root,COG0145@2|Bacteria,3Y6D5@57723|Acidobacteria,2JKXC@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158380_k127_4107581_0	378806.STAUR_7251	7.695e-105	351.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,43C12@68525|delta/epsilon subdivisions,2WXMX@28221|Deltaproteobacteria,2Z37R@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_4107581_2	1123355.JHYO01000013_gene1144	2.437e-84	295.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,36Y2U@31993|Methylocystaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,MFS_2,Sugar_tr
SRR25158380_k127_4107581_4	1323663.AROI01000003_gene2241	3.252e-26	113.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158380_k127_4107581_3	1121396.KB893062_gene2736	1.877e-43	166.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,2MJVE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158380_k127_4121036_0	1128421.JAGA01000003_gene2902	2.534e-127	417.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	iJN678.pfkA	PFK
SRR25158380_k127_4121036_2	234267.Acid_6710	4.162e-42	159.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria	57723|Acidobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158380_k127_4121036_1	234267.Acid_6711	1.718e-51	190.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,DUF4833
SRR25158380_k127_4121167_0	1242864.D187_004920	1.034e-224	709.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158380_k127_4137529_1	215803.DB30_4242	4.34e-62	216.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,434NI@68525|delta/epsilon subdivisions,2WYZV@28221|Deltaproteobacteria,2Z10X@29|Myxococcales	28221|Deltaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_4137529_0	373994.Riv7116_3783	2.054e-69	254.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HRAP@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_4137529_2	204669.Acid345_0209	4.271e-21	106.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria,2JKFK@204432|Acidobacteriia	204432|Acidobacteriia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158380_k127_4155164_2	330214.NIDE2777	1.196e-56	208.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	yddE	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158380_k127_4155164_1	531844.FIC_02452	5.05e-58	214.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia,406Q0@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
SRR25158380_k127_4155164_0	292459.STH1319	3.47e-60	212.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158380_k127_4159515_5	1121396.KB892900_gene2129	0.0007954	53.0	COG1657@1|root,COG2374@1|root,COG2931@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG5306@1|root,COG1657@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5306@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
SRR25158380_k127_4159515_3	977880.pRALTA_0341	9.436e-59	233.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158380_k127_4159515_2	977880.pRALTA_0338	6.551e-77	291.0	COG1520@1|root,COG1520@2|Bacteria,1NTVM@1224|Proteobacteria	1224|Proteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4159515_4	234267.Acid_4775	1.235e-42	181.0	COG1361@1|root,COG1649@1|root,COG1361@2|Bacteria,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Glyco_hydro_42M,PKD,SLH,WG_beta_rep
SRR25158380_k127_4159515_1	64471.sync_2679	1.277e-146	477.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_4159515_0	204669.Acid345_1052	3.482e-185	608.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_4164067_0	861299.J421_1410	2.069e-180	574.0	COG0624@1|root,COG0624@2|Bacteria,1ZSYH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158380_k127_4164067_1	546414.Deide_03660	3.236e-43	169.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158380_k127_4167036_0	1267533.KB906736_gene1071	6.498e-265	839.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria,2JK7N@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_4167036_1	204669.Acid345_0618	1.845e-217	703.0	COG0577@1|root,COG0577@2|Bacteria,3Y6E4@57723|Acidobacteria,2JM2S@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_4167036_3	1267535.KB906767_gene5108	6.393e-187	612.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria,2JITF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_4167036_2	1183438.GKIL_4354	7.016e-197	643.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_4167036_4	1267535.KB906767_gene4612	2.824e-34	135.0	COG0577@1|root,COG0577@2|Bacteria	1267535.KB906767_gene4612|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4168776_0	926550.CLDAP_36890	0.0	1707.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158380_k127_4183242_1	1382306.JNIM01000001_gene313	5.914e-45	166.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT,MaoC_dehydrat_N,MaoC_dehydratas
SRR25158380_k127_4183242_2	314230.DSM3645_13855	1.989e-40	154.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
SRR25158380_k127_4183242_4	269797.Mbar_A3620	2.6e-23	113.0	COG3291@1|root,COG3391@1|root,arCOG03991@1|root,arCOG02510@2157|Archaea,arCOG03563@2157|Archaea,arCOG03991@2157|Archaea,2Y2RX@28890|Euryarchaeota,2NAHT@224756|Methanomicrobia	224756|Methanomicrobia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PKD
SRR25158380_k127_4183242_3	1004785.AMBLS11_10285	8.897e-36	140.0	2E363@1|root,32Y5Y@2|Bacteria,1P1I8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4183242_0	234267.Acid_1867	2.653e-163	523.0	COG0665@1|root,COG0665@2|Bacteria,3Y5BS@57723|Acidobacteria	57723|Acidobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303,ko:K21061	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R00610,R11428	RC00060,RC00135,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158380_k127_4190110_0	1379698.RBG1_1C00001G0862	1.14e-139	465.0	COG4772@1|root,COG4772@2|Bacteria,2NRIP@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158380_k127_4190110_3	717231.Flexsi_0787	1.629e-15	81.0	COG1734@1|root,COG1734@2|Bacteria,2GFP6@200930|Deferribacteres	200930|Deferribacteres	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158380_k127_4190110_1	404380.Gbem_0470	1.367e-88	301.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158380_k127_4190110_2	794903.OPIT5_24060	6.235e-60	214.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4192018_2	1499967.BAYZ01000014_gene6406	4.549e-59	213.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158380_k127_4192018_4	1089553.Tph_c14180	2.376e-11	76.0	COG1807@1|root,COG1807@2|Bacteria,1V1HJ@1239|Firmicutes,249BG@186801|Clostridia,42HAV@68295|Thermoanaerobacterales	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_4192018_5	1333998.M2A_1571	1.032e-05	50.0	COG0500@1|root,COG2226@2|Bacteria,1QWJE@1224|Proteobacteria,2U37M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_4192018_1	936573.HMPREF1147_2351	9.261e-82	292.0	COG0438@1|root,COG0438@2|Bacteria,1UWIQ@1239|Firmicutes,4H8GD@909932|Negativicutes	909932|Negativicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
SRR25158380_k127_4192018_3	1177154.Y5S_03293	3.777e-18	98.0	COG2244@1|root,COG2244@2|Bacteria,1PMCM@1224|Proteobacteria,1T9CG@1236|Gammaproteobacteria,1XMN7@135619|Oceanospirillales	135619|Oceanospirillales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158380_k127_4192018_0	517418.Ctha_2023	1.275e-182	591.0	COG0367@1|root,COG0367@2|Bacteria,1FDEI@1090|Chlorobi	1090|Chlorobi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158380_k127_42064_2	204669.Acid345_0895	4.518e-48	175.0	COG0451@1|root,COG0451@2|Bacteria,3Y3J3@57723|Acidobacteria,2JIFZ@204432|Acidobacteriia	204432|Acidobacteriia	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158380_k127_42064_0	886293.Sinac_3294	8.485e-130	424.0	COG0399@1|root,COG0399@2|Bacteria,2IXRE@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158380_k127_42064_1	671143.DAMO_0194	2.156e-97	344.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SRR25158380_k127_4209402_3	762984.HMPREF9445_01450	1.154e-41	176.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes,2FNFY@200643|Bacteroidia,4ANF6@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4962)	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
SRR25158380_k127_4209402_1	448385.sce6459	1.388e-154	500.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_4209402_5	1443665.JACA01000033_gene1779	9.464e-08	65.0	COG3204@1|root,COG5434@1|root,COG3204@2|Bacteria,COG5434@2|Bacteria,4P0KA@976|Bacteroidetes,1IHRV@117743|Flavobacteriia,2YJ0K@290174|Aquimarina	976|Bacteroidetes	M	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
SRR25158380_k127_4209402_0	861299.J421_6019	3.422e-205	647.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	2|Bacteria	E	Amino acid permease	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
SRR25158380_k127_4209402_4	1424334.W822_01630	1.004e-34	141.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158380_k127_4209402_2	1123242.JH636434_gene4128	2.126e-50	182.0	COG5285@1|root,COG5285@2|Bacteria,2IXYK@203682|Planctomycetes	203682|Planctomycetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158380_k127_4214711_1	1382359.JIAL01000001_gene2337	4.216e-87	302.0	COG2355@1|root,COG2355@2|Bacteria,3Y39A@57723|Acidobacteria,2JI1H@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158380_k127_4214711_2	234267.Acid_5984	3.016e-68	243.0	COG0648@1|root,COG0648@2|Bacteria,3Y35C@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158380_k127_4214711_0	1379281.AVAG01000065_gene1155	6.944e-169	542.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2M9Q4@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158380_k127_4219551_2	861299.J421_3004	1.955e-25	107.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_4219551_1	861299.J421_4310	1.145e-35	155.0	2EA12@1|root,3346D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158380_k127_4219551_0	760117.JN27_22600	1.057e-61	235.0	2DVZY@1|root,33XWI@2|Bacteria	2|Bacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158380_k127_4219551_3	882082.SaccyDRAFT_2844	8.235e-24	107.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4ECD8@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_4220040_4	756272.Plabr_2113	2.1e-31	124.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158380_k127_4220040_1	204669.Acid345_4390	5.905e-62	243.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_4220040_2	234267.Acid_5042	2.141e-58	208.0	COG0041@1|root,COG0041@2|Bacteria,3Y4MB@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158380_k127_4220040_0	1267535.KB906767_gene2200	3.675e-233	732.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_4220040_3	335543.Sfum_0084	1.396e-34	138.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158380_k127_4220040_5	1192034.CAP_2403	2.371e-18	86.0	COG0750@1|root,COG0823@1|root,COG2234@1|root,COG0750@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158380_k127_4221771_6	443144.GM21_1216	1.368e-17	86.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
SRR25158380_k127_4221771_7	1190603.AJYD01000026_gene3285	7.03e-06	58.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K00666,ko:K03561,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01004,ko02000,ko03110	1.A.30.2.1	-	-	AMP-binding,AMP-binding_C,DUF1499,DUF4157
SRR25158380_k127_4221771_0	349163.Acry_3069	0.0	1030.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2TRT7@28211|Alphaproteobacteria,2JV12@204441|Rhodospirillales	204441|Rhodospirillales	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
SRR25158380_k127_4221771_3	886293.Sinac_2406	2.052e-98	332.0	COG3520@1|root,COG3520@2|Bacteria,2IZ33@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, VC_A0111 family	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
SRR25158380_k127_4221771_2	330214.NIDE1983	4.473e-187	603.0	COG3519@1|root,COG3519@2|Bacteria,3J114@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:T6SS_VipB	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
SRR25158380_k127_4221771_5	886293.Sinac_2408	1.039e-39	153.0	COG3518@1|root,COG3518@2|Bacteria,2J0UC@203682|Planctomycetes	203682|Planctomycetes	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
SRR25158380_k127_4221771_4	234267.Acid_0233	6.327e-53	190.0	COG3157@1|root,COG3157@2|Bacteria,3Y5QP@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SRR25158380_k127_4221771_1	330214.NIDE1978	8.164e-222	693.0	COG3517@1|root,COG3517@2|Bacteria,3J0Z9@40117|Nitrospirae	40117|Nitrospirae	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
SRR25158380_k127_4240853_2	649638.Trad_2700	1.465e-73	254.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_4240853_4	1128427.KB904821_gene4050	9.501e-16	89.0	COG0457@1|root,COG3063@1|root,COG4995@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158380_k127_4240853_3	771875.Ferpe_1363	9.115e-54	192.0	COG1490@1|root,COG1490@2|Bacteria,2GCYQ@200918|Thermotogae	200918|Thermotogae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158380_k127_4240853_5	251229.Chro_1771	3.242e-08	60.0	2EE59@1|root,337ZW@2|Bacteria,1G955@1117|Cyanobacteria,3VMXN@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4240853_0	497964.CfE428DRAFT_1607	0.0	1289.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158380_k127_4240853_1	237368.SCABRO_03745	9.287e-198	627.0	COG1012@1|root,COG1012@2|Bacteria,2IXV2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158380_k127_4245044_2	1382359.JIAL01000001_gene748	2.978e-96	319.0	COG3934@1|root,COG3934@2|Bacteria,3Y387@57723|Acidobacteria,2JJ00@204432|Acidobacteriia	204432|Acidobacteriia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
SRR25158380_k127_4245044_0	1268240.ATFI01000001_gene2804	3.03e-271	856.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,2FN3P@200643|Bacteroidia,4AMTA@815|Bacteroidaceae	976|Bacteroidetes	D	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
SRR25158380_k127_4245044_1	204669.Acid345_0903	1.056e-195	616.0	COG2115@1|root,COG2115@2|Bacteria,3Y841@57723|Acidobacteria,2JNHR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the xylose isomerase family	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158380_k127_4248749_1	316273.XCV0477	6.221e-18	91.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,LTD
SRR25158380_k127_4248749_2	929562.Emtol_1024	7.901e-05	46.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
SRR25158380_k127_4248749_0	661478.OP10G_1553	5.062e-47	183.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_4256968_0	459349.CLOAM0423	3.474e-214	673.0	COG1260@1|root,COG1260@2|Bacteria,2NP2I@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158380_k127_4256968_2	1041139.KB902602_gene169	8.377e-24	112.0	COG4977@1|root,COG4977@2|Bacteria,1R9KM@1224|Proteobacteria,2VF6H@28211|Alphaproteobacteria,4BA78@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC
SRR25158380_k127_4256968_1	1196028.ALEF01000053_gene3521	6.172e-38	152.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,4C4IM@84406|Virgibacillus	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	ugpQ_1	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158380_k127_4256968_3	1379698.RBG1_1C00001G1249	6.722e-12	76.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158380_k127_4265141_0	926550.CLDAP_21080	5.12e-265	836.0	COG0474@1|root,COG0474@2|Bacteria,2G60Z@200795|Chloroflexi	200795|Chloroflexi	P	Cation transporting ATPase, C-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158380_k127_4265141_3	348780.NP_1892A	1.895e-13	81.0	COG0589@1|root,arCOG00449@2157|Archaea,2XTY0@28890|Euryarchaeota,23TV5@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_4265141_1	204669.Acid345_2891	3.017e-49	187.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158380_k127_4265141_2	1255043.TVNIR_1705	3.921e-40	164.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_4266733_4	1499967.BAYZ01000182_gene4451	1.569e-08	56.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_4266733_1	1499967.BAYZ01000182_gene4451	1.006e-119	398.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_4266733_2	1254432.SCE1572_49595	6.135e-15	86.0	28PVU@1|root,2ZCGC@2|Bacteria,1QT5D@1224|Proteobacteria,43570@68525|delta/epsilon subdivisions,2X96D@28221|Deltaproteobacteria,2Z272@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4266733_0	1408473.JHXO01000011_gene3120	1.034e-240	759.0	COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,2FPDW@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_4266733_3	1111730.ATTM01000008_gene714	9.499e-13	70.0	2E3Q4@1|root,32YN3@2|Bacteria,4NVYD@976|Bacteroidetes,1IE48@117743|Flavobacteriia,2NZU2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4279678_0	215803.DB30_3103	5.969e-244	773.0	COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,42YD5@68525|delta/epsilon subdivisions,2X313@28221|Deltaproteobacteria,2YTXH@29|Myxococcales	28221|Deltaproteobacteria	G	Putative carbohydrate binding domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
SRR25158380_k127_4279678_1	234267.Acid_3496	2.153e-131	427.0	COG0457@1|root,COG0457@2|Bacteria,3Y3WM@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_4281984_3	1121346.KB899881_gene2312	1.966e-14	85.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4IQKZ@91061|Bacilli,276F6@186822|Paenibacillaceae	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
SRR25158380_k127_4281984_0	1382359.JIAL01000001_gene901	1.823e-310	991.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158380_k127_4281984_2	653733.Selin_0089	1.394e-45	172.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
SRR25158380_k127_4281984_1	1304888.ATWF01000001_gene1132	1.288e-141	466.0	COG1190@1|root,COG1190@2|Bacteria,2GEUY@200930|Deferribacteres	200930|Deferribacteres	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_4282338_1	1123325.JHUV01000011_gene1500	1.82e-52	187.0	COG1217@1|root,COG1217@2|Bacteria,2G4QC@200783|Aquificae	200783|Aquificae	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158380_k127_4282338_2	500635.MITSMUL_03576	2.726e-47	174.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4H4C1@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158380_k127_4282338_4	1121920.AUAU01000009_gene1940	1.085e-06	59.0	COG2165@1|root,COG2165@2|Bacteria,3Y9CD@57723|Acidobacteria	57723|Acidobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4282338_6	926566.Terro_2938	0.0001064	53.0	COG0823@1|root,COG3391@1|root,COG0823@2|Bacteria,COG3391@2|Bacteria,3Y31A@57723|Acidobacteria,2JHIN@204432|Acidobacteriia	57723|Acidobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4282338_5	1340493.JNIF01000003_gene1706	7.714e-05	53.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SRR25158380_k127_4282338_0	1089548.KI783301_gene2821	4.242e-67	236.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,3WFAX@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
SRR25158380_k127_4282338_3	102129.Lepto7375DRAFT_2420	3.23e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158380_k127_4290173_2	1120973.AQXL01000111_gene934	1.123e-72	258.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,279I3@186823|Alicyclobacillaceae	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_4290173_1	234267.Acid_7565	2.65e-132	437.0	COG2227@1|root,COG2227@2|Bacteria,3Y71H@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4290173_4	1034347.CAHJ01000009_gene1897	1.749e-58	210.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158380_k127_4290173_5	1392490.JHZX01000001_gene2437	2.673e-24	109.0	COG3409@1|root,COG3409@2|Bacteria,4NT07@976|Bacteroidetes,1I8V1@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158380_k127_4290173_0	1198114.AciX9_1369	4.545e-267	838.0	COG5276@1|root,COG5276@2|Bacteria,3Y393@57723|Acidobacteria,2JMHD@204432|Acidobacteriia	2|Bacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158380_k127_4290173_3	1198114.AciX9_1370	3.325e-71	250.0	COG3544@1|root,COG3544@2|Bacteria,3Y4G7@57723|Acidobacteria,2JKAH@204432|Acidobacteriia	2|Bacteria	P	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158380_k127_4315824_0	1166018.FAES_3194	3.445e-291	928.0	COG0642@1|root,COG0840@1|root,COG1352@1|root,COG2201@1|root,COG2203@1|root,COG0642@2|Bacteria,COG0840@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2203@2|Bacteria,4PKNJ@976|Bacteroidetes,47JHY@768503|Cytophagia	976|Bacteroidetes	NT	protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158380_k127_4315824_1	1123508.JH636456_gene135	2.313e-73	252.0	COG2197@1|root,COG2197@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_4315824_2	111780.Sta7437_0822	6.377e-48	181.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,3VJMP@52604|Pleurocapsales	1117|Cyanobacteria	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_4320730_2	525904.Tter_2869	7.53e-74	257.0	COG3211@1|root,COG3211@2|Bacteria	2|Bacteria	O	Phosphatase	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158380_k127_4320730_3	485913.Krac_1911	5.573e-38	145.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158380_k127_4320730_0	1330700.JQNC01000001_gene2140	4.65e-122	404.0	COG1404@1|root,COG1404@2|Bacteria,1WIDU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	3.4.21.111	ko:K20754	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I9,Peptidase_S8
SRR25158380_k127_4320730_1	234267.Acid_3593	1.139e-96	343.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_4327591_1	744980.TRICHSKD4_0837	1.901e-130	423.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
SRR25158380_k127_4327591_2	671143.DAMO_1598	3.687e-121	400.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158380_k127_4327591_3	240015.ACP_0992	4.83e-43	164.0	COG0457@1|root,COG0457@2|Bacteria	240015.ACP_0992|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4327591_4	1267533.KB906735_gene4868	6.96e-34	141.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,3Y40V@57723|Acidobacteria,2JI0P@204432|Acidobacteriia	204432|Acidobacteriia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
SRR25158380_k127_4333310_2	795359.TOPB45_0563	6.587e-06	48.0	COG0442@1|root,COG0442@2|Bacteria,2GH47@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158380_k127_4333310_1	1382304.JNIL01000001_gene2347	2.351e-45	169.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,278B9@186823|Alicyclobacillaceae	91061|Bacilli	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158380_k127_4333310_0	639282.DEFDS_0485	3.238e-173	553.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158380_k127_4335908_11	1163407.UU7_00325	6.796e-06	55.0	COG4319@1|root,COG4319@2|Bacteria,1QDB7@1224|Proteobacteria,1T990@1236|Gammaproteobacteria,1XBUD@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_4335908_5	1380394.JADL01000002_gene1628	2.31e-35	136.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,2JXIK@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158380_k127_4335908_2	1499967.BAYZ01000194_gene3125	1.464e-50	182.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158380_k127_4335908_7	869213.JCM21142_104243	2.513e-25	117.0	COG2340@1|root,COG2340@2|Bacteria,4P06D@976|Bacteroidetes	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158380_k127_4335908_8	1173023.KE650771_gene3983	1.232e-19	91.0	COG3393@1|root,COG3393@2|Bacteria,1GF6E@1117|Cyanobacteria	1117|Cyanobacteria	S	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SRR25158380_k127_4335908_1	530564.Psta_1705	6.394e-77	268.0	COG4912@1|root,COG4912@2|Bacteria,2IZ0C@203682|Planctomycetes	203682|Planctomycetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158380_k127_4335908_4	1242864.D187_007675	3.941e-39	154.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria	1224|Proteobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158380_k127_4335908_6	1192034.CAP_5806	1.444e-28	126.0	2APZ5@1|root,31F41@2|Bacteria,1RHIH@1224|Proteobacteria	1224|Proteobacteria	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158380_k127_4335908_3	452637.Oter_1075	6.102e-40	155.0	arCOG09454@1|root,30G4A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4335908_0	555088.DealDRAFT_0530	6.206e-80	273.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24JSE@186801|Clostridia,42KMW@68298|Syntrophomonadaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158380_k127_4340000_2	1121920.AUAU01000002_gene2079	5.661e-23	99.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158380_k127_4340000_3	1267535.KB906767_gene1042	0.0009616	50.0	COG5662@1|root,COG5662@2|Bacteria,3Y4S0@57723|Acidobacteria	57723|Acidobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158380_k127_4340000_0	1340493.JNIF01000003_gene2787	4.74e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4340000_1	215803.DB30_6971	6.891e-35	147.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158380_k127_4343005_3	1267535.KB906767_gene1002	2.822e-36	144.0	COG2365@1|root,COG2365@2|Bacteria,3Y8BW@57723|Acidobacteria	57723|Acidobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
SRR25158380_k127_4343005_5	448385.sce8962	1.471e-15	84.0	2ECF7@1|root,336DF@2|Bacteria,1NWPM@1224|Proteobacteria,432XS@68525|delta/epsilon subdivisions,2WY0M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4343005_1	933115.GPDM_07005	1.405e-98	330.0	COG2321@1|root,COG2321@2|Bacteria,1TQKF@1239|Firmicutes,4HB7I@91061|Bacilli,26E8G@186818|Planococcaceae	91061|Bacilli	S	Putative neutral zinc metallopeptidase	XK27_03670	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158380_k127_4343005_4	1445613.JALM01000005_gene1186	1.577e-25	111.0	COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_4343005_0	357808.RoseRS_2336	1.724e-120	391.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_4343005_2	926549.KI421517_gene1084	2.015e-79	270.0	28JXC@1|root,2Z8EX@2|Bacteria,4NF7D@976|Bacteroidetes,47M9Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4343985_0	1382306.JNIM01000001_gene3764	3.159e-138	449.0	COG0277@1|root,COG0277@2|Bacteria,2G8B5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158380_k127_4343985_2	1499967.BAYZ01000009_gene5328	1.284e-39	168.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
SRR25158380_k127_4343985_3	211165.AJLN01000116_gene2992	7.711e-22	104.0	COG0500@1|root,COG2226@2|Bacteria,1G96Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4343985_4	211165.AJLN01000116_gene2992	5.031e-19	94.0	COG0500@1|root,COG2226@2|Bacteria,1G96Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4343985_1	1122919.KB905549_gene2050	6.682e-65	246.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,4HKSK@91061|Bacilli,26YUS@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4343985_5	1346791.M529_00705	6.26e-18	98.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158380_k127_4352780_1	204669.Acid345_1576	5.201e-206	656.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158380_k127_4352780_7	1550073.JROH01000009_gene1300	0.0007044	46.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158380_k127_4352780_4	234267.Acid_6428	2.676e-45	169.0	COG0590@1|root,COG0590@2|Bacteria,3Y4KB@57723|Acidobacteria	57723|Acidobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	DUF3175,MafB19-deam
SRR25158380_k127_4352780_3	316274.Haur_4101	7.901e-64	231.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
SRR25158380_k127_4352780_2	1382359.JIAL01000001_gene2082	1.128e-195	621.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia	204432|Acidobacteriia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158380_k127_4352780_6	861299.J421_3379	1.68e-11	69.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
SRR25158380_k127_4352780_0	204669.Acid345_1048	4.209e-271	842.0	COG2987@1|root,COG2987@2|Bacteria,3Y2VD@57723|Acidobacteria,2JK4Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Urocanase Rossmann-like domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158380_k127_4352780_5	1123277.KB893185_gene3032	2.059e-43	171.0	COG0627@1|root,COG0627@2|Bacteria,4NE7D@976|Bacteroidetes,47KC0@768503|Cytophagia	976|Bacteroidetes	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_435349_7	743719.PaelaDRAFT_0115	2.296e-09	62.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_435349_4	1340493.JNIF01000003_gene4251	1.475e-46	182.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
SRR25158380_k127_435349_5	234267.Acid_7266	1.167e-45	179.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SRR25158380_k127_435349_2	868595.Desca_1252	1.455e-85	295.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,2607F@186807|Peptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158380_k127_435349_1	1191523.MROS_0721	3.009e-150	483.0	COG1932@1|root,COG1932@2|Bacteria	2|Bacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158380_k127_435349_3	313612.L8106_25715	1.27e-72	252.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1H8N9@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158380_k127_435349_0	234267.Acid_3960	1.163e-173	552.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158380_k127_435349_6	945713.IALB_0156	3.614e-28	113.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
SRR25158380_k127_4353562_1	204669.Acid345_1052	6.799e-160	533.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_4353562_0	1443111.JASG01000004_gene421	3.246e-259	813.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3ZUWI@60136|Sulfitobacter	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158380_k127_4354703_0	330214.NIDE2540	2.502e-144	469.0	COG0044@1|root,COG0044@2|Bacteria,3J0D7@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158380_k127_4354703_1	338963.Pcar_1615	6.619e-126	411.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158380_k127_4354703_3	1392502.JNIO01000008_gene2287	3.864e-65	227.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4H3ZG@909932|Negativicutes	909932|Negativicutes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158380_k127_4354703_2	272134.KB731324_gene1653	2.885e-102	344.0	COG0167@1|root,COG0167@2|Bacteria,1G1C2@1117|Cyanobacteria,1H89S@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158380_k127_4354703_4	1121428.DESHY_110148___1	6.951e-62	221.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,261JP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158380_k127_4354703_6	879212.DespoDRAFT_02050	2.044e-09	70.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WNBB@28221|Deltaproteobacteria,2MK5J@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158380_k127_4354703_7	234267.Acid_2866	0.0004344	53.0	2DBU8@1|root,2ZB4S@2|Bacteria,3Y31B@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158380_k127_4354703_5	682795.AciX8_3624	4.872e-22	106.0	COG0672@1|root,COG0672@2|Bacteria,3Y3XB@57723|Acidobacteria,2JI3D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Iron permease FTR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318,FTR1
SRR25158380_k127_4359170_1	215803.DB30_5220	4.612e-96	320.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,2YXI1@29|Myxococcales	28221|Deltaproteobacteria	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
SRR25158380_k127_4359170_2	1037409.BJ6T_26450	1.104e-59	213.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,3JR3Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158380_k127_4359170_3	746697.Aeqsu_3029	1.678e-55	200.0	COG5483@1|root,COG5483@2|Bacteria,4NNWS@976|Bacteroidetes,1I1Z4@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158380_k127_4359170_0	234267.Acid_5076	7.874e-138	445.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158380_k127_4359170_5	234267.Acid_2313	1.542e-05	50.0	2EVWN@1|root,33PAB@2|Bacteria,3Y5UR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4359170_4	242159.ABO97252	1.036e-54	196.0	COG1208@1|root,KOG1322@2759|Eukaryota,37N08@33090|Viridiplantae,34H4G@3041|Chlorophyta	3041|Chlorophyta	H	This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP- glucose from Glc-1-P and ATP	ADG1	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_435960_2	1121920.AUAU01000018_gene1775	1.093e-08	59.0	COG2318@1|root,COG2318@2|Bacteria,3Y4HW@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_435960_1	1121451.DESAM_22229	8.004e-110	364.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2M95X@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158380_k127_435960_3	1267533.KB906736_gene991	1.14e-06	54.0	COG3829@1|root,COG3829@2|Bacteria,3Y5JE@57723|Acidobacteria,2JJZ2@204432|Acidobacteriia	204432|Acidobacteriia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
SRR25158380_k127_435960_0	682795.AciX8_1477	6.144e-205	647.0	COG0463@1|root,COG0500@1|root,COG0463@2|Bacteria,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	phcB	-	2.1.1.295,2.1.1.79	ko:K00574,ko:K12240,ko:K18534,ko:K19620,ko:K20444	ko00130,ko01053,ko01100,ko01110,ko02020,map00130,map01053,map01100,map01110,map02020	M00112	R07501,R10709,R10710	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000,ko01005,ko01008,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,HNH_4,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31,Polyketide_cyc2
SRR25158380_k127_4369071_2	243090.RB4667	1.385e-91	315.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4369071_3	379066.GAU_3062	1.688e-29	121.0	COG1586@1|root,COG1586@2|Bacteria,1ZV1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
SRR25158380_k127_4369071_1	1121920.AUAU01000009_gene1851	1.885e-159	525.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158380_k127_4369071_4	1192034.CAP_1496	1.074e-15	80.0	2DI1Z@1|root,301RV@2|Bacteria,1NM7Q@1224|Proteobacteria,433HJ@68525|delta/epsilon subdivisions,2WXZG@28221|Deltaproteobacteria,2Z1QD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158380_k127_4369071_0	903818.KI912268_gene728	5.638e-191	610.0	COG4262@1|root,COG4262@2|Bacteria,3Y3M2@57723|Acidobacteria	57723|Acidobacteria	S	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158380_k127_4370351_3	204669.Acid345_1455	1.366e-39	157.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_4370351_2	743722.Sph21_0865	5.696e-49	183.0	COG0262@1|root,COG0262@2|Bacteria,4NR4N@976|Bacteroidetes,1IYRH@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158380_k127_4370351_0	379066.GAU_3347	5.728e-95	323.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	dppA	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
SRR25158380_k127_4370351_4	1223410.KN050846_gene233	9.548e-15	79.0	2DG1V@1|root,2ZU42@2|Bacteria,4P88S@976|Bacteroidetes,1IB24@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4370351_1	448385.sce2381	5.388e-71	245.0	COG0262@1|root,COG0262@2|Bacteria,1R7YJ@1224|Proteobacteria,42ZF9@68525|delta/epsilon subdivisions,2WUSX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158380_k127_4374483_3	74547.PMT_0620	1.03e-26	114.0	COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria,1MM1S@1212|Prochloraceae	1117|Cyanobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_4374483_4	251221.35212931	1.225e-20	100.0	COG2340@1|root,COG2340@2|Bacteria,1G6DK@1117|Cyanobacteria	1117|Cyanobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158380_k127_4374483_2	682795.AciX8_4624	1.141e-28	132.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria,2JHVA@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR25158380_k127_4374483_0	479434.Sthe_1685	2.671e-76	261.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi,27Y7N@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158380_k127_4374483_5	1463909.KL585969_gene4647	0.0001101	52.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158380_k127_4374483_1	177437.HRM2_27010	2.477e-43	165.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,2MI5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SRR25158380_k127_438768_1	204669.Acid345_2395	1.27e-55	200.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
SRR25158380_k127_438768_0	1519464.HY22_04445	2.067e-262	826.0	COG1770@1|root,COG1770@2|Bacteria,1FDQZ@1090|Chlorobi	1090|Chlorobi	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.21.26,3.4.21.83	ko:K01322,ko:K01354	ko04614,ko05142,ko05143,map04614,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158380_k127_438768_6	633149.Bresu_0306	2.72e-10	64.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,2KH13@204458|Caulobacterales	204458|Caulobacterales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158380_k127_438768_3	1303518.CCALI_00532	9.582e-28	115.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRR25158380_k127_438768_4	41875.XP_007511676.1	4.64e-25	117.0	28M8C@1|root,2S5PV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_438768_2	1157490.EL26_19490	9.088e-31	127.0	COG0492@1|root,COG0492@2|Bacteria,1V4WN@1239|Firmicutes,4HHA8@91061|Bacilli,278DV@186823|Alicyclobacillaceae	91061|Bacilli	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_438963_2	926566.Terro_0050	3.488e-26	112.0	COG0640@1|root,COG0640@2|Bacteria,3Y7J1@57723|Acidobacteria,2JMRU@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158380_k127_438963_1	1121957.ATVL01000001_gene3519	1.019e-54	198.0	COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,47Q9R@768503|Cytophagia	976|Bacteroidetes	M	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158380_k127_438963_0	401526.TcarDRAFT_1596	6.125e-218	693.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158380_k127_4401967_1	671143.DAMO_0325	1.958e-84	289.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
SRR25158380_k127_4401967_0	251221.35214297	4.963e-117	392.0	COG1301@1|root,COG1301@2|Bacteria,1G32C@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
SRR25158380_k127_4401967_2	700598.Niako_5211	1.228e-65	229.0	COG0705@1|root,COG0705@2|Bacteria,4NJG9@976|Bacteroidetes,1J16X@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158380_k127_4438469_2	574087.Acear_0347	5.722e-24	119.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,3WBZ5@53433|Halanaerobiales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158380_k127_4438469_4	1121445.ATUZ01000013_gene1164	3.458e-06	61.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria,2M91B@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SRR25158380_k127_4438469_0	204669.Acid345_4424	8.314e-101	337.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JIT2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158380_k127_4438469_1	234267.Acid_4781	1.003e-48	181.0	COG0237@1|root,COG0237@2|Bacteria,3Y4R2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158380_k127_4438469_3	1411685.U062_00186	1.993e-18	90.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1J6HF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158380_k127_4439183_0	1340493.JNIF01000003_gene1501	3.879e-70	256.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,VIT,VWA_3
SRR25158380_k127_4439183_3	234267.Acid_7691	1.411e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4439183_1	1521187.JPIM01000006_gene1743	3.257e-45	169.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,375KP@32061|Chloroflexia	32061|Chloroflexia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158380_k127_4439183_4	420324.KI912090_gene7191	8.676e-22	95.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2U2CB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_4465968_0	1499967.BAYZ01000014_gene6405	2.98e-56	203.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
SRR25158380_k127_4465968_1	57918.XP_004296559.1	9.024e-07	62.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MB0@33090|Viridiplantae,3GFCB@35493|Streptophyta,4JKX4@91835|fabids	35493|Streptophyta	O	metalloendoproteinase 1-like	-	-	3.4.24.34	ko:K01402,ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
SRR25158380_k127_4468732_1	1267535.KB906767_gene1129	9.01e-85	308.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_4468732_0	426117.M446_0613	8.792e-135	436.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,1JT1V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_4468732_2	748727.CLJU_c14900	8.837e-49	186.0	COG0657@1|root,COG0657@2|Bacteria,1UFB9@1239|Firmicutes,24DFS@186801|Clostridia,36HTV@31979|Clostridiaceae	186801|Clostridia	I	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158380_k127_4468732_3	234267.Acid_3196	1.458e-12	71.0	COG1598@1|root,COG1598@2|Bacteria,3Y8ZR@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4473684_0	1267535.KB906767_gene277	3.432e-68	235.0	2DB97@1|root,33TRP@2|Bacteria,3Y7NY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4473684_1	404589.Anae109_4072	2.711e-35	143.0	293J8@1|root,2ZR19@2|Bacteria,1R6Y4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4475796_4	471854.Dfer_0264	1.187e-17	98.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SRR25158380_k127_4475796_1	1163409.UUA_03818	7.055e-133	448.0	COG3055@1|root,COG3055@2|Bacteria,1NHAC@1224|Proteobacteria,1RYBY@1236|Gammaproteobacteria,1XAGU@135614|Xanthomonadales	135614|Xanthomonadales	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4475796_0	1340493.JNIF01000003_gene4527	6.343e-311	968.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria	57723|Acidobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR25158380_k127_4475796_3	383372.Rcas_0814	1.5e-35	146.0	294HY@1|root,2ZRXK@2|Bacteria,2GAIJ@200795|Chloroflexi,376D9@32061|Chloroflexia	32061|Chloroflexia	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158380_k127_4475796_2	1267535.KB906767_gene1046	1.601e-54	203.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
SRR25158380_k127_4484242_1	234267.Acid_2667	1.403e-81	273.0	COG4948@1|root,COG4948@2|Bacteria,3Y4P2@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158380_k127_4484242_0	518766.Rmar_1079	1.185e-283	888.0	COG3661@1|root,COG3661@2|Bacteria,4NHE2@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	-	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
SRR25158380_k127_4484242_2	204669.Acid345_0640	7.562e-75	257.0	COG0657@1|root,COG0657@2|Bacteria,3Y44Z@57723|Acidobacteria,2JJYN@204432|Acidobacteriia	204432|Acidobacteriia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158380_k127_4492919_1	997346.HMPREF9374_1651	6.557e-83	299.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,27CSD@186824|Thermoactinomycetaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158380_k127_4492919_2	1304284.L21TH_1713	6.736e-61	241.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,36EE8@31979|Clostridiaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158380_k127_4492919_0	378806.STAUR_6796	1.743e-147	482.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,2YZC9@29|Myxococcales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158380_k127_4492919_3	339671.Asuc_1210	2.537e-12	78.0	COG0417@1|root,COG0417@2|Bacteria,1QVMG@1224|Proteobacteria,1T2EP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
SRR25158380_k127_4500431_2	886293.Sinac_3998	3.457e-36	145.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158380_k127_4500431_0	661478.OP10G_0672	1.202e-60	225.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158380_k127_4500431_1	234267.Acid_4096	2.035e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4520121_1	335543.Sfum_2435	1.693e-94	326.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42Q6P@68525|delta/epsilon subdivisions,2X5QT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_4520121_2	1437425.CSEC_1842	8.512e-80	277.0	COG0121@1|root,COG0121@2|Bacteria,2JG9A@204428|Chlamydiae	204428|Chlamydiae	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
SRR25158380_k127_4520121_6	1122132.AQYH01000003_gene3064	1.197e-07	55.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,4B7RZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Cation transport ATPase	MA20_24480	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158380_k127_4520121_7	1541065.JRFE01000058_gene5500	3.906e-07	55.0	2CCNX@1|root,30VV4@2|Bacteria,1GG7R@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4520121_5	204669.Acid345_2190	1.058e-18	92.0	2AAGQ@1|root,30ZTQ@2|Bacteria,3Y4IN@57723|Acidobacteria,2JJDR@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
SRR25158380_k127_4520121_4	525904.Tter_2724	7.849e-38	146.0	COG3439@1|root,COG3439@2|Bacteria,2NPV1@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158380_k127_4520121_0	1267534.KB906756_gene711	7.779e-102	341.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_4520121_3	443144.GM21_0398	3.743e-42	169.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Ail_Lom,MtrB_PioB
SRR25158380_k127_4536067_1	671143.DAMO_2651	1.121e-261	822.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158380_k127_4536067_6	479434.Sthe_1830	3.822e-123	413.0	COG1070@1|root,COG1070@2|Bacteria,2G5KJ@200795|Chloroflexi,27XI8@189775|Thermomicrobia	189775|Thermomicrobia	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158380_k127_4536067_9	204669.Acid345_2517	9.911e-59	212.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
SRR25158380_k127_4536067_4	635013.TherJR_2416	9.843e-145	466.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,2621Y@186807|Peptococcaceae	186801|Clostridia	E	PFAM Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158380_k127_4536067_3	204669.Acid345_1271	1.467e-166	539.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158380_k127_4536067_0	204669.Acid345_1270	1.707e-294	908.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158380_k127_4536067_10	756067.MicvaDRAFT_2499	5.106e-43	161.0	COG2337@1|root,COG2337@2|Bacteria,1G7HN@1117|Cyanobacteria,1HC7E@1150|Oscillatoriales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158380_k127_4536067_11	179408.Osc7112_3980	2.975e-05	49.0	2EK59@1|root,334WP@2|Bacteria,1G981@1117|Cyanobacteria,1HDGK@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4536067_2	204669.Acid345_1269	5.259e-175	556.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158380_k127_4536067_5	1267533.KB906741_gene405	3.173e-134	437.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia	204432|Acidobacteriia	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158380_k127_4536067_7	1089547.KB913013_gene2542	2.105e-107	362.0	COG0531@1|root,COG0531@2|Bacteria,4NIPF@976|Bacteroidetes,47M1K@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_4536067_8	768706.Desor_3549	9.884e-59	216.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_4539930_0	888727.HMPREF9092_0060	6.427e-33	133.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,3WCI2@538999|Clostridiales incertae sedis	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158380_k127_454057_2	234267.Acid_3798	2.458e-172	568.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_3798|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_454057_0	1267535.KB906767_gene3207	1.23e-213	691.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	2|Bacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_454057_1	1183438.GKIL_4354	3.914e-197	641.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_454057_4	485913.Krac_12070	4.822e-24	108.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158380_k127_454057_3	1278073.MYSTI_01766	1.515e-53	194.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_454445_2	1122963.AUHB01000007_gene3522	5.079e-07	55.0	COG3375@1|root,COG3375@2|Bacteria,1RCQ2@1224|Proteobacteria,2U4YM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_454445_1	1118054.CAGW01000024_gene451	2.488e-108	367.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,26SYE@186822|Paenibacillaceae	91061|Bacilli	E	peptidase M20	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_454445_0	1267535.KB906767_gene2507	4.027e-225	715.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158380_k127_4550802_2	234267.Acid_0490	1.117e-201	644.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SRR25158380_k127_4550802_1	1128421.JAGA01000003_gene2871	1.387e-217	683.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SRR25158380_k127_4550802_7	1128421.JAGA01000003_gene2872	1.131e-63	224.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SRR25158380_k127_4550802_8	1340493.JNIF01000004_gene149	8.384e-54	200.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158380_k127_4550802_4	1128421.JAGA01000003_gene2874	3.419e-109	368.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4550802_5	234267.Acid_0496	6.304e-88	301.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158380_k127_4550802_3	204669.Acid345_2996	9.021e-114	376.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158380_k127_4550802_0	234267.Acid_0498	1.337e-275	857.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158380_k127_4550802_6	1267533.KB906741_gene402	7.85e-73	253.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria,2JI50@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158380_k127_4550802_9	1128421.JAGA01000003_gene2880	7.1e-20	94.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158380_k127_4560285_1	1267533.KB906733_gene3499	1.712e-87	308.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158380_k127_4560285_0	1382306.JNIM01000001_gene3772	3.952e-107	357.0	COG0604@1|root,COG0604@2|Bacteria,2G7Z0@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_4560285_3	69279.BG36_13835	5.243e-26	119.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,2U7IG@28211|Alphaproteobacteria,43JD5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158380_k127_4560285_2	204669.Acid345_2809	1.609e-47	174.0	COG0698@1|root,COG0698@2|Bacteria,3Y50S@57723|Acidobacteria,2JJEK@204432|Acidobacteriia	204432|Acidobacteriia	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158380_k127_456531_0	861299.J421_2525	1.13e-154	519.0	COG0277@1|root,COG0277@2|Bacteria,1ZT11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158380_k127_4566980_1	925409.KI911562_gene2401	8.372e-25	108.0	COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1J056@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158380_k127_4566980_0	351160.RCIX1164	2.875e-58	216.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158380_k127_4570685_1	1184267.A11Q_79	1.993e-47	179.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4570685_0	1196322.A370_04715	1.67e-56	203.0	28PHV@1|root,2ZC86@2|Bacteria,1VBR0@1239|Firmicutes,24FVU@186801|Clostridia,36IC6@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4570685_3	1128421.JAGA01000002_gene1099	3.594e-20	97.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158380_k127_4570685_2	28072.Nos7524_4000	9.058e-22	98.0	2C3PV@1|root,3307H@2|Bacteria,1GB76@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2834)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2834
SRR25158380_k127_4572280_2	1267535.KB906767_gene4788	2.094e-66	235.0	COG2755@1|root,COG2755@2|Bacteria,3Y4BD@57723|Acidobacteria,2JMAI@204432|Acidobacteriia	204432|Acidobacteriia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158380_k127_4572280_0	861299.J421_5606	3.504e-218	683.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158380_k127_4572280_1	861299.J421_5600	1.265e-75	257.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
SRR25158380_k127_4578055_2	8153.XP_005928010.1	1.412e-14	83.0	COG0666@1|root,KOG4369@1|root,KOG0502@2759|Eukaryota,KOG0504@2759|Eukaryota,KOG4369@2759|Eukaryota,38I05@33154|Opisthokonta,3BHRH@33208|Metazoa,3CU4I@33213|Bilateria,484TK@7711|Chordata,48VFT@7742|Vertebrata,49TED@7898|Actinopterygii	33208|Metazoa	T	Ankyrin repeat and KH	ANKHD1	GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0010639,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0016043,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0040011,GO:0042692,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045087,GO:0045214,GO:0046530,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051146,GO:0051704,GO:0051707,GO:0051716,GO:0055001,GO:0055002,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0090596,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:1903146,GO:1903147	-	ko:K16726	-	-	-	-	ko00000,ko03036	-	-	-	Ank_2,Ank_4,KH_1
SRR25158380_k127_4578055_0	760192.Halhy_4155	2.061e-56	216.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Asp_protease_2,BAAT_C,DLH
SRR25158380_k127_4578055_1	653733.Selin_0517	3.222e-45	168.0	COG1272@1|root,COG1272@2|Bacteria	2|Bacteria	K	protein, Hemolysin III	hly3	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158380_k127_4580902_1	204669.Acid345_4214	1.468e-79	277.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158380_k127_4580902_2	485913.Krac_2076	9.765e-51	186.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158380_k127_4580902_0	240015.ACP_2265	5.698e-101	337.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158380_k127_4581687_0	234267.Acid_4491	0.0	1025.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158380_k127_4581687_2	933262.AXAM01000062_gene954	6.606e-73	255.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MHX7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SRR25158380_k127_4581687_3	335543.Sfum_3369	9.653e-66	247.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MQUA@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DSHCT	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SRR25158380_k127_4581687_1	63737.Npun_R0239	2.082e-126	413.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158380_k127_4581687_4	1144275.COCOR_06701	0.0001109	46.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YYWU@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_4592897_0	1254432.SCE1572_00460	5.443e-313	996.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2YUG5@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158380_k127_4592897_1	1192034.CAP_3148	3.087e-277	888.0	COG3857@1|root,COG3857@2|Bacteria,1QXU1@1224|Proteobacteria,43C6K@68525|delta/epsilon subdivisions,2X7GU@28221|Deltaproteobacteria,2Z1DQ@29|Myxococcales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158380_k127_4592897_2	1869.MB27_30450	3.291e-32	135.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158380_k127_4595702_0	344747.PM8797T_00899	4.007e-174	553.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158380_k127_4595702_6	1037409.BJ6T_23810	5.289e-13	72.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158380_k127_4595702_5	1379698.RBG1_1C00001G0336	5.075e-14	81.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158380_k127_4595702_1	1037409.BJ6T_23800	1.403e-135	435.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR25158380_k127_4595702_2	448385.sce4861	1.118e-36	155.0	COG5337@1|root,COG5337@2|Bacteria,1Q378@1224|Proteobacteria,438XY@68525|delta/epsilon subdivisions,2X9VC@28221|Deltaproteobacteria,2YY5I@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
SRR25158380_k127_4595702_4	1239962.C943_03877	2.037e-17	86.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158380_k127_4595702_3	234267.Acid_7565	3.852e-18	86.0	COG2227@1|root,COG2227@2|Bacteria,3Y71H@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4597530_2	1379270.AUXF01000001_gene2297	3.247e-58	224.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,1ZUB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158380_k127_4597530_1	880073.Calab_3696	8.791e-81	280.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158380_k127_4597530_0	379066.GAU_3101	5.513e-127	414.0	COG0714@1|root,COG0714@2|Bacteria,1ZUSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158380_k127_4597530_3	63737.Npun_R1867	5.522e-07	59.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1HQX3@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
SRR25158380_k127_4601316_1	2754.EH55_00790	1.986e-132	436.0	COG1012@1|root,COG1012@2|Bacteria,3TA1S@508458|Synergistetes	508458|Synergistetes	C	PFAM Aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158380_k127_4601316_6	1519464.HY22_04930	1.24e-37	145.0	COG4577@1|root,COG4577@2|Bacteria,1FFDI@1090|Chlorobi	1090|Chlorobi	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
SRR25158380_k127_4601316_7	390333.Ldb0597	4.495e-13	77.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae	91061|Bacilli	S	Helix-turn-helix domain	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
SRR25158380_k127_4601316_0	243231.GSU2195	1.953e-208	657.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,43TA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158380_k127_4601316_5	215803.DB30_8737	1.815e-46	175.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,2YXH0@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR25158380_k127_4601316_4	292459.STH2424	1.034e-49	188.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158380_k127_4601316_2	1121957.ATVL01000007_gene1796	3.024e-97	342.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47KE2@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158380_k127_4601316_3	292459.STH2766	3.123e-83	290.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158380_k127_4613427_6	401053.AciPR4_1386	1.952e-52	192.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria,2JHY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_4613427_8	1382359.JIAL01000001_gene2868	2.172e-17	96.0	COG3485@1|root,COG3485@2|Bacteria,3Y44E@57723|Acidobacteria,2JIGS@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_4613427_0	204669.Acid345_3357	2.057e-184	612.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
SRR25158380_k127_4613427_2	1382359.JIAL01000001_gene2411	2.097e-126	420.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_4613427_1	63737.Npun_R3591	4.455e-144	493.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,1G09B@1117|Cyanobacteria,1HMTJ@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_4613427_7	203124.Tery_4220	1.199e-20	97.0	COG1733@1|root,COG1733@2|Bacteria,1G7DW@1117|Cyanobacteria,1HBWZ@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_4613427_3	518766.Rmar_0181	1.308e-116	386.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1FIUF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_4613427_5	1197130.BAFM01000003_gene657	1.687e-77	270.0	COG1250@1|root,arCOG00250@2157|Archaea,2XT9S@28890|Euryarchaeota,23TDY@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd1	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_4613427_4	1121468.AUBR01000026_gene2914	1.379e-80	278.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_4613427_9	1144275.COCOR_01967	9.837e-06	56.0	COG0457@1|root,COG3063@1|root,COG5178@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,COG5178@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	A	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
SRR25158380_k127_4625501_1	234267.Acid_1598	1.009e-110	367.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158380_k127_4625501_0	861299.J421_3029	4.544e-147	490.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
SRR25158380_k127_4625501_2	1379270.AUXF01000002_gene1832	1.826e-27	113.0	COG4299@1|root,COG4299@2|Bacteria,1ZT4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
SRR25158380_k127_4634205_1	1183438.GKIL_1779	1.562e-31	128.0	COG2272@1|root,COG3187@1|root,COG2272@2|Bacteria,COG3187@2|Bacteria,1GA7U@1117|Cyanobacteria	1117|Cyanobacteria	O	META domain	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	META
SRR25158380_k127_4634205_0	1379270.AUXF01000005_gene474	2.084e-137	462.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_4641341_3	224911.27355976	1.185e-08	64.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158380_k127_4641341_2	639030.JHVA01000001_gene2810	2.22e-23	107.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,GerE,Trans_reg_C
SRR25158380_k127_4641341_1	1173026.Glo7428_0940	4.266e-137	451.0	COG0654@1|root,COG0654@2|Bacteria,1G27V@1117|Cyanobacteria	1117|Cyanobacteria	CH	Monooxygenase fad-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4641341_0	290397.Adeh_3381	2.035e-208	662.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42PZF@68525|delta/epsilon subdivisions,2X5HR@28221|Deltaproteobacteria,2YYCV@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_4652264_1	671143.DAMO_2385	5.177e-23	102.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158380_k127_4652264_0	748727.CLJU_c14410	4.068e-38	162.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,36DRS@31979|Clostridiaceae	186801|Clostridia	M	Peptidase, S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158380_k127_4652939_0	247490.KSU1_C0714	3.339e-162	544.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
SRR25158380_k127_4652939_5	1121957.ATVL01000008_gene4544	4.169e-95	323.0	COG2885@1|root,COG2885@2|Bacteria,4NI3U@976|Bacteroidetes,47MNU@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
SRR25158380_k127_4652939_8	316274.Haur_0049	2.147e-63	226.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_4652939_2	861299.J421_5995	2.769e-112	390.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	AAA_16,Abhydrolase_1,PD40,Trans_reg_C
SRR25158380_k127_4652939_7	404589.Anae109_2307	4.185e-67	246.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158380_k127_4652939_12	880073.Calab_1042	3.289e-12	72.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158380_k127_4652939_3	1123508.JH636439_gene1341	6.115e-106	359.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158380_k127_4652939_9	1172181.KB911698_gene5892	4.007e-48	181.0	COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158380_k127_4652939_13	1034943.BN1094_03642	1.073e-09	65.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,1S96R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_4652939_1	1384056.N787_06630	6.866e-131	427.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158380_k127_4652939_6	521045.Kole_0509	2.645e-71	247.0	COG1794@1|root,COG1794@2|Bacteria	2|Bacteria	M	racemase activity, acting on amino acids and derivatives	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS14520	Asp_Glu_race
SRR25158380_k127_4652939_11	662479.C440_06662	1.242e-14	79.0	COG0076@1|root,arCOG00027@2157|Archaea,2Y37G@28890|Euryarchaeota,23ZDQ@183963|Halobacteria	183963|Halobacteria	E	COG0076 Glutamate decarboxylase and related PLP-dependent proteins	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158380_k127_4652939_4	395961.Cyan7425_2945	3.337e-105	348.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
SRR25158380_k127_4665983_0	204669.Acid345_3065	9.158e-203	645.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
SRR25158380_k127_4665983_6	671143.DAMO_2577	4.329e-06	51.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158380_k127_4665983_4	1265505.ATUG01000002_gene2756	5.74e-55	200.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2MJYH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158380_k127_4665983_2	644282.Deba_2078	1.768e-57	211.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YicC domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158380_k127_4665983_1	204669.Acid345_3781	1.846e-138	462.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158380_k127_4665983_3	292459.STH750	5.43e-57	207.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia	186801|Clostridia	K	response regulator receiver	phoP	-	-	ko:K02483,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_4665983_5	1267535.KB906767_gene3728	4.086e-26	118.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158380_k127_4680945_0	1123376.AUIU01000002_gene1663	9.466e-301	941.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158380_k127_4680945_5	247490.KSU1_B0183	1.643e-13	76.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158380_k127_4680945_1	204669.Acid345_4041	1.306e-63	222.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJC7@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158380_k127_4680945_7	1192034.CAP_5045	9.577e-10	70.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158380_k127_4680945_2	234267.Acid_0793	1.929e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4680945_6	234267.Acid_0791	1.041e-11	75.0	2DMGW@1|root,32REM@2|Bacteria,3Y4XX@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
SRR25158380_k127_4680945_3	546274.EIKCOROL_01508	6.741e-37	150.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,2KS3X@206351|Neisseriales	206351|Neisseriales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158380_k127_4680945_4	360911.EAT1b_1944	6.623e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli	91061|Bacilli	K	Cold-Shock Protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158380_k127_4684491_0	234267.Acid_3358	4.657e-174	571.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_4684491_1	929562.Emtol_1353	1.246e-146	477.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_4686359_2	1499967.BAYZ01000009_gene5337	6.779e-05	55.0	2EKNX@1|root,33ECP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4686359_1	1340493.JNIF01000004_gene952	3.064e-06	59.0	COG0671@1|root,COG1075@1|root,COG0671@2|Bacteria,COG1075@2|Bacteria,3Y7BS@57723|Acidobacteria	57723|Acidobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
SRR25158380_k127_4686359_0	1042375.AFPL01000012_gene695	2.794e-43	168.0	COG1463@1|root,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,4680F@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
SRR25158380_k127_4688631_3	278963.ATWD01000001_gene4283	5.737e-15	79.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria,2JJDW@204432|Acidobacteriia	204432|Acidobacteriia	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158380_k127_4688631_0	671143.DAMO_2531	9.101e-108	360.0	COG0533@1|root,COG0533@2|Bacteria,2NNXP@2323|unclassified Bacteria	2|Bacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Peptidase_M22
SRR25158380_k127_4688631_2	204669.Acid345_3242	3.141e-86	291.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria,2JIBF@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_4692249_0	886293.Sinac_0940	1.262e-147	481.0	COG2234@1|root,COG2234@2|Bacteria,2IZHS@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_4710917_0	247490.KSU1_C0066	2.328e-89	305.0	COG0123@1|root,COG0123@2|Bacteria,2IXK9@203682|Planctomycetes	203682|Planctomycetes	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158380_k127_4710917_2	289376.THEYE_A1912	0.0003415	49.0	2ERUX@1|root,33JE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4710917_1	240015.ACP_1738	1.813e-85	302.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria,2JHXN@204432|Acidobacteriia	204432|Acidobacteriia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158380_k127_4714957_0	1382306.JNIM01000001_gene2629	5.525e-119	400.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158380_k127_4714957_2	391600.ABRU01000039_gene1962	8.811e-33	139.0	COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,2U7GA@28211|Alphaproteobacteria,2KGBW@204458|Caulobacterales	204458|Caulobacterales	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VanY
SRR25158380_k127_4714957_4	1382359.JIAL01000001_gene1533	2.006e-05	56.0	28MS6@1|root,2ZB0K@2|Bacteria,3Y38I@57723|Acidobacteria,2JHU5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4714957_1	765911.Thivi_1432	7.033e-68	244.0	COG4850@1|root,COG4850@2|Bacteria,1R3ST@1224|Proteobacteria,1RYC6@1236|Gammaproteobacteria,1WZHP@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158380_k127_4714957_3	547045.NEISICOT_02160	1.351e-17	91.0	29355@1|root,2ZQN9@2|Bacteria,1RFN1@1224|Proteobacteria,2VSAG@28216|Betaproteobacteria,2KR84@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4715176_3	404589.Anae109_3248	1.583e-98	327.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria	1224|Proteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158380_k127_4715176_1	204669.Acid345_2716	6.388e-172	573.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_4715176_4	44454.NF84_14150	3.326e-67	238.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,234HP@1762|Mycobacteriaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158380_k127_4715176_2	234267.Acid_5446	5.973e-100	338.0	COG0665@1|root,COG0665@2|Bacteria,3Y3W7@57723|Acidobacteria	57723|Acidobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158380_k127_4715176_5	1123277.KB893180_gene2348	1.06e-46	172.0	2D4D1@1|root,32TGT@2|Bacteria,4NUAV@976|Bacteroidetes,47S3Q@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4715176_0	204669.Acid345_1052	2e-173	574.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158380_k127_4715176_6	1340493.JNIF01000003_gene4251	2.672e-39	160.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
SRR25158380_k127_4732954_2	1173264.KI913949_gene2156	1.113e-22	100.0	COG0845@1|root,COG0845@2|Bacteria,1G29R@1117|Cyanobacteria,1H9Z0@1150|Oscillatoriales	1117|Cyanobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158380_k127_4732954_0	1173024.KI912148_gene3732	9.551e-291	913.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_4732954_1	1173024.KI912148_gene3740	7.035e-111	364.0	COG1136@1|root,COG1136@2|Bacteria,1G4IP@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_4736742_2	240015.ACP_0231	6.187e-44	168.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria,2JIJ3@204432|Acidobacteriia	204432|Acidobacteriia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158380_k127_4736742_1	204669.Acid345_3454	2.924e-49	184.0	COG2930@1|root,COG2930@2|Bacteria,3Y2F0@57723|Acidobacteria,2JIT6@204432|Acidobacteriia	204432|Acidobacteriia	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SRR25158380_k127_4736742_4	1267533.KB906734_gene3780	3.983e-23	110.0	COG0526@1|root,COG0526@2|Bacteria,3Y5DD@57723|Acidobacteria,2JJQP@204432|Acidobacteriia	204432|Acidobacteriia	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_4736742_3	426114.THI_3098	1.721e-35	138.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1KKHS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	E1-E2 ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158380_k127_4736742_0	1125863.JAFN01000001_gene1462	1.687e-181	576.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158380_k127_4737459_0	986075.CathTA2_0529	1.86e-54	199.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli	91061|Bacilli	S	protein containing SIS (Sugar ISomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158380_k127_4737459_2	56110.Oscil6304_4931	1.463e-43	171.0	COG2971@1|root,COG2971@2|Bacteria,1G3SA@1117|Cyanobacteria,1H9RT@1150|Oscillatoriales	1117|Cyanobacteria	G	BadF BadG BcrA BcrD	-	-	2.7.1.59	ko:K00884,ko:K02616	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	BcrAD_BadFG
SRR25158380_k127_4737459_1	344747.PM8797T_12328	6.184e-47	184.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Peptidase_S9
SRR25158380_k127_4737459_3	1033743.CAES01000078_gene3653	2.711e-29	137.0	COG4733@1|root,COG4733@2|Bacteria,1TXSD@1239|Firmicutes,4I0BE@91061|Bacilli,271I2@186822|Paenibacillaceae	91061|Bacilli	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
SRR25158380_k127_473943_1	1382359.JIAL01000001_gene1871	3.042e-55	207.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158380_k127_473943_2	670487.Ocepr_1236	6.798e-11	73.0	COG0457@1|root,COG0457@2|Bacteria,1WIGW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SRR25158380_k127_473943_0	1340493.JNIF01000004_gene275	5.612e-72	269.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene275|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_473943_3	240015.ACP_2501	0.0008703	43.0	COG0845@1|root,COG0845@2|Bacteria,3Y2FV@57723|Acidobacteria,2JHN2@204432|Acidobacteriia	204432|Acidobacteriia	M	MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SRR25158380_k127_4739727_3	1232683.ADIMK_0334	4.815e-14	72.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158380_k127_4739727_2	1121920.AUAU01000023_gene2406	7.611e-29	130.0	2DMMW@1|root,32SIJ@2|Bacteria,3Y8YH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4739727_0	760568.Desku_2097	8.528e-123	405.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,265TC@186807|Peptococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4739727_1	326427.Cagg_1652	2.299e-70	251.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4748245_4	1122915.AUGY01000043_gene7823	2.493e-39	155.0	COG4221@1|root,COG4221@2|Bacteria,1V9C1@1239|Firmicutes,4ISDS@91061|Bacilli,26S84@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
SRR25158380_k127_4748245_0	861299.J421_6259	1.3e-185	599.0	COG0366@1|root,COG0366@2|Bacteria,1ZUGN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Cyclomaltodextrinase, N-terminal	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_N
SRR25158380_k127_4748245_1	383372.Rcas_2968	6e-179	574.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158380_k127_4748245_2	861299.J421_6259	5.254e-165	539.0	COG0366@1|root,COG0366@2|Bacteria,1ZUGN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Cyclomaltodextrinase, N-terminal	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_N
SRR25158380_k127_4748245_3	639030.JHVA01000001_gene1923	4.172e-46	186.0	COG0457@1|root,COG0457@2|Bacteria,3Y93T@57723|Acidobacteria	57723|Acidobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
SRR25158380_k127_4748245_5	1382359.JIAL01000001_gene84	5.788e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria,2JM74@204432|Acidobacteriia	204432|Acidobacteriia	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_6,TPR_8
SRR25158380_k127_4765784_0	42256.RradSPS_1100	3.158e-117	382.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158380_k127_4765784_5	204669.Acid345_1110	3.862e-72	250.0	COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria,2JNG0@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158380_k127_4765784_9	485916.Dtox_0239	6.359e-44	173.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,261DG@186807|Peptococcaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
SRR25158380_k127_4765784_4	204669.Acid345_2567	3.806e-80	281.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria,2JI98@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158380_k127_4765784_7	908338.HMPREF9286_1107	1.171e-47	175.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,22GIV@1570339|Peptoniphilaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158380_k127_4765784_8	903818.KI912268_gene1881	1.338e-47	173.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158380_k127_4765784_1	204669.Acid345_0563	5.655e-103	343.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158380_k127_4765784_3	767817.Desgi_1828	9.049e-82	277.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158380_k127_4765784_2	483219.LILAB_34540	6.875e-95	316.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158380_k127_4765784_6	234267.Acid_0903	3.667e-64	224.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158380_k127_4765784_10	1216932.CM240_2952	1.418e-16	83.0	2D62R@1|root,32TKD@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158380_k127_4779603_0	272134.KB731324_gene3218	1.115e-155	517.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MHYT,PAS,PAS_3,PAS_9
SRR25158380_k127_4779603_1	926566.Terro_3767	1.23e-27	128.0	COG0457@1|root,COG0457@2|Bacteria,3Y2VC@57723|Acidobacteria,2JHR2@204432|Acidobacteriia	204432|Acidobacteriia	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158380_k127_4783443_3	644282.Deba_1890	9.041e-33	131.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	molybdenum cofactor	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158380_k127_4783443_2	330214.NIDE4359	2.28e-42	158.0	COG1832@1|root,COG1832@2|Bacteria,3J19F@40117|Nitrospirae	40117|Nitrospirae	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158380_k127_4783443_0	1267535.KB906767_gene717	0.0	1416.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria,2JIJZ@204432|Acidobacteriia	204432|Acidobacteriia	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158380_k127_4783443_1	118168.MC7420_6649	6.55e-69	244.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1H968@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_4783443_4	204669.Acid345_0060	3.218e-27	114.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158380_k127_4788865_3	563192.HMPREF0179_01287	1.009e-45	168.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2WK2U@28221|Deltaproteobacteria,2MAU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158380_k127_4788865_5	401526.TcarDRAFT_0245	0.0003248	47.0	COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,4H1YI@909932|Negativicutes	909932|Negativicutes	S	Beta-lactamase superfamily domain	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158380_k127_4788865_1	316274.Haur_0260	4.827e-83	290.0	COG0589@1|root,COG3842@1|root,COG0589@2|Bacteria,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,3758E@32061|Chloroflexia	2|Bacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
SRR25158380_k127_4788865_4	1134413.ANNK01000145_gene3755	7.953e-29	121.0	COG1959@1|root,COG1959@2|Bacteria,1VGP5@1239|Firmicutes,4HW56@91061|Bacilli,1ZH0X@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158380_k127_4788865_0	316274.Haur_0259	2.945e-128	418.0	COG1613@1|root,COG1613@2|Bacteria	2|Bacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
SRR25158380_k127_4788865_2	886293.Sinac_0630	2.199e-78	273.0	COG0555@1|root,COG0555@2|Bacteria,2IYF4@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM sulfate ABC transporter	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158380_k127_4788974_1	234267.Acid_1127	3.358e-63	223.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_4788974_0	1183438.GKIL_3395	1.221e-190	622.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_4795948_2	1123242.JH636434_gene5626	1.708e-41	158.0	COG4886@1|root,COG5426@1|root,COG4886@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,Flg_new,LRR_5,LRR_6
SRR25158380_k127_4795948_1	1173028.ANKO01000116_gene5761	2.613e-58	215.0	COG0500@1|root,COG0500@2|Bacteria,1GQFM@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_4795948_3	1297742.A176_06042	6.598e-32	129.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
SRR25158380_k127_4795948_5	1123277.KB893243_gene361	1.334e-21	97.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
SRR25158380_k127_4795948_4	886293.Sinac_1023	2.938e-24	104.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
SRR25158380_k127_4795948_0	1128427.KB904821_gene2140	1.465e-68	244.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G0BI@1117|Cyanobacteria,1H9XU@1150|Oscillatoriales	1117|Cyanobacteria	S	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
SRR25158380_k127_4803390_1	452637.Oter_0169	8.847e-265	828.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
SRR25158380_k127_4803390_4	1415755.JQLV01000001_gene3380	3.061e-13	80.0	COG1737@1|root,COG1737@2|Bacteria,1MW2B@1224|Proteobacteria,1RNDZ@1236|Gammaproteobacteria,1XJ9P@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator, RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158380_k127_4803390_3	1382359.JIAL01000001_gene2567	7.212e-121	401.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	204432|Acidobacteriia	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158380_k127_4803390_0	234267.Acid_1968	2.333e-301	968.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat
SRR25158380_k127_4803390_2	29581.BW37_00870	1.665e-234	738.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2WBDI@28216|Betaproteobacteria,475K6@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158380_k127_4809053_3	234267.Acid_6380	2.137e-06	51.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_6380|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4809053_1	234267.Acid_7677	3.85e-52	190.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158380_k127_4809053_0	909663.KI867150_gene2380	3.285e-99	334.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SRR25158380_k127_4809053_2	329726.AM1_3473	8.638e-20	95.0	COG1572@1|root,COG1572@2|Bacteria,1GFRU@1117|Cyanobacteria	1117|Cyanobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
SRR25158380_k127_4813182_0	1047013.AQSP01000121_gene2702	2.332e-127	428.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158380_k127_4813182_1	251221.35211765	5.168e-70	246.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_4816191_0	1242864.D187_004126	4.534e-100	339.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
SRR25158380_k127_4821732_2	706587.Desti_1906	1.53e-33	131.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	AlkA N-terminal domain	ada	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158380_k127_4821732_1	1267535.KB906767_gene5134	9.328e-51	197.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4821732_0	479434.Sthe_3188	3.837e-52	193.0	29KMP@1|root,307IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158380_k127_4821732_4	1463917.JODC01000008_gene3202	8.03e-07	51.0	COG2374@1|root,COG2374@2|Bacteria,2IIDP@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4821732_3	1192034.CAP_3704	9.546e-09	57.0	COG2374@1|root,COG2374@2|Bacteria,1QTNH@1224|Proteobacteria,43809@68525|delta/epsilon subdivisions,2X3AA@28221|Deltaproteobacteria,2YV3X@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4830708_1	1122603.ATVI01000010_gene1065	2.978e-44	176.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RR2N@1236|Gammaproteobacteria,1X3V4@135614|Xanthomonadales	135614|Xanthomonadales	G	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158380_k127_4830708_0	269799.Gmet_0304	4.917e-293	918.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,42NS6@68525|delta/epsilon subdivisions,2WKYJ@28221|Deltaproteobacteria,43SD8@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158380_k127_4838883_2	313606.M23134_03754	2.742e-19	98.0	2DS14@1|root,33E1R@2|Bacteria,4NXJ9@976|Bacteroidetes,47SSF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR25158380_k127_4838883_0	316067.Geob_3650	7.676e-217	694.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SRR25158380_k127_4838883_1	404589.Anae109_2844	1.463e-32	132.0	2EC6I@1|root,33651@2|Bacteria,1N6AT@1224|Proteobacteria,432YU@68525|delta/epsilon subdivisions,2WXQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4839979_2	1267535.KB906767_gene3177	8.747e-142	458.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158380_k127_4839979_5	868595.Desca_0689	4.937e-56	201.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,261YZ@186807|Peptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158380_k127_4839979_6	1267535.KB906767_gene2786	6.765e-39	150.0	2DB97@1|root,32TX2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4839979_0	85643.Tmz1t_2563	3.208e-254	807.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,2KUM5@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158380_k127_4839979_1	671143.DAMO_2181	4.912e-171	546.0	COG1219@1|root,COG1219@2|Bacteria,2NNN2@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158380_k127_4839979_8	1304275.C41B8_05828	5.539e-06	52.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158380_k127_4839979_3	177437.HRM2_04380	7.665e-90	299.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,2MJ0K@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158380_k127_4839979_4	1340493.JNIF01000003_gene2845	6.069e-61	227.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158380_k127_4839979_7	411473.RUMCAL_01655	1.807e-07	55.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJCV@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158380_k127_4852195_1	1205753.A989_04491	7.358e-45	169.0	COG3554@1|root,COG3554@2|Bacteria,1PV1Y@1224|Proteobacteria,1STFX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycolipid_bind
SRR25158380_k127_4852195_3	1173027.Mic7113_0582	4.006e-08	64.0	COG3409@1|root,COG3409@2|Bacteria,1GR82@1117|Cyanobacteria,1HIA0@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4852195_0	1267535.KB906767_gene3810	7.993e-183	589.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_485238_0	29581.BW37_00870	1.892e-225	709.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2WBDI@28216|Betaproteobacteria,475K6@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158380_k127_485238_1	489825.LYNGBM3L_43410	5.78e-150	490.0	COG1680@1|root,COG1680@2|Bacteria,1G7C0@1117|Cyanobacteria,1HD9W@1150|Oscillatoriales	1117|Cyanobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158380_k127_485238_2	1047013.AQSP01000139_gene2322	3.939e-113	377.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_4852450_1	1123261.AXDW01000004_gene2796	7.673e-56	209.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,1S3FZ@1236|Gammaproteobacteria,1X54C@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_4852450_3	1223410.KN050846_gene2423	5.159e-05	46.0	COG2159@1|root,COG2159@2|Bacteria,4NK6T@976|Bacteroidetes,1I2BN@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158380_k127_4852450_2	1499967.BAYZ01000073_gene2011	3.9e-34	136.0	COG1610@1|root,COG1610@2|Bacteria,2NPQ9@2323|unclassified Bacteria	2|Bacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158380_k127_4852450_0	82654.Pse7367_2149	7.139e-97	329.0	COG2755@1|root,COG2755@2|Bacteria,1G3BA@1117|Cyanobacteria	1117|Cyanobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
SRR25158380_k127_4853933_1	1408433.JHXV01000008_gene153	4.602e-150	492.0	COG3291@1|root,COG4188@1|root,COG3291@2|Bacteria,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,1HZ4A@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
SRR25158380_k127_4853933_3	1340493.JNIF01000003_gene2233	8.324e-56	199.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158380_k127_4853933_0	1267535.KB906767_gene2168	9.041e-249	787.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria,2JMHB@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158380_k127_4853933_2	103690.17133031	4.406e-87	294.0	COG1028@1|root,COG1028@2|Bacteria,1GDEA@1117|Cyanobacteria,1HRGV@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_4854136_1	1267533.KB906736_gene1175	1.212e-16	89.0	COG2885@1|root,COG2885@2|Bacteria,3Y425@57723|Acidobacteria,2JHR8@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158380_k127_4854136_0	1267533.KB906738_gene2436	7.635e-177	584.0	COG1629@1|root,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_4854136_2	278963.ATWD01000001_gene1515	1.259e-05	51.0	COG4974@1|root,COG4974@2|Bacteria,3Y574@57723|Acidobacteria,2JJQH@204432|Acidobacteriia	204432|Acidobacteriia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158380_k127_4863225_1	926566.Terro_0838	3.991e-77	264.0	COG3403@1|root,COG3403@2|Bacteria,3Y7H4@57723|Acidobacteria	57723|Acidobacteria	S	YqcI/YcgG family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4863225_0	204669.Acid345_2716	6.089e-161	541.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158380_k127_4864078_2	251221.35214259	3.83e-36	144.0	COG0612@1|root,COG0612@2|Bacteria,1G303@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_4864078_0	1163408.UU9_04689	8.569e-153	495.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1X5E6@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_4864078_3	671143.DAMO_2924	5.012e-08	58.0	2CBGA@1|root,33A66@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4864078_1	1345697.M493_14850	3.972e-75	275.0	COG0265@1|root,COG0265@2|Bacteria,1UYZJ@1239|Firmicutes,4HFHN@91061|Bacilli,1WHAK@129337|Geobacillus	91061|Bacilli	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158380_k127_4864078_4	718252.FP2_27280	1.554e-05	58.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,MFS_1
SRR25158380_k127_4869182_3	1178825.ALIH01000008_gene721	0.0001259	47.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158380_k127_4869182_2	76114.ebA6732	1.332e-20	98.0	2DP2V@1|root,330AH@2|Bacteria,1R3EE@1224|Proteobacteria,2VUJY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
SRR25158380_k127_4869182_1	1267533.KB906734_gene4302	4.629e-43	180.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria	57723|Acidobacteria	KU	WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158380_k127_4869182_0	1267533.KB906735_gene4675	6.929e-75	257.0	2D579@1|root,32TID@2|Bacteria,3Y88C@57723|Acidobacteria,2JNCR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4879392_0	1386089.N865_20905	2.862e-116	379.0	COG2267@1|root,COG2267@2|Bacteria,2HEX8@201174|Actinobacteria,4FIB8@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158380_k127_4879392_4	314278.NB231_01848	5.548e-06	51.0	2DDVB@1|root,2ZJEV@2|Bacteria,1PBKE@1224|Proteobacteria,1SUSK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158380_k127_4879392_3	340177.Cag_1752	3.782e-18	87.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158380_k127_4879392_1	1295642.H839_10723	6.496e-73	253.0	COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli	91061|Bacilli	GM	Dehydratase	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158380_k127_4888058_0	1382359.JIAL01000001_gene12	1e-323	1002.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_4888058_3	1335760.ASTG01000009_gene253	6.357e-05	53.0	2EBPI@1|root,335PM@2|Bacteria,1R3KC@1224|Proteobacteria,2UNS1@28211|Alphaproteobacteria,2K160@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4888058_2	1090319.KE386571_gene437	1.925e-06	58.0	2EBPI@1|root,335PM@2|Bacteria,1R3KC@1224|Proteobacteria,2UNS1@28211|Alphaproteobacteria,2K160@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4888058_1	1562701.BBOF01000043_gene1425	9.154e-31	124.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,1K0GR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	transglycosylase	slt	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	SLT
SRR25158380_k127_4888108_1	518766.Rmar_2484	1.09e-87	301.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRR25158380_k127_4888108_0	1034943.BN1094_02096	2.547e-153	495.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_4888108_2	1455608.JDTH01000001_gene3232	0.0001337	53.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTT5@28890|Euryarchaeota,23UP1@183963|Halobacteria	183963|Halobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_4889402_0	326427.Cagg_1652	1.959e-57	218.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4889402_1	211165.AJLN01000116_gene2992	2.762e-24	119.0	COG0500@1|root,COG2226@2|Bacteria,1G96Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4889402_2	1415779.JOMH01000001_gene124	1.849e-10	74.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158380_k127_4892201_3	314230.DSM3645_06489	2.775e-07	53.0	COG1232@1|root,COG1232@2|Bacteria,2IWT1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158380_k127_4892201_2	1163407.UU7_00325	8.018e-09	62.0	COG4319@1|root,COG4319@2|Bacteria,1QDB7@1224|Proteobacteria,1T990@1236|Gammaproteobacteria,1XBUD@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_4892201_0	1144275.COCOR_02369	1.632e-100	357.0	COG0421@1|root,COG0421@2|Bacteria,1QYV9@1224|Proteobacteria	1224|Proteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158380_k127_4892201_1	204669.Acid345_0630	6.544e-53	201.0	COG1721@1|root,COG1721@2|Bacteria,3Y5V9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158380_k127_4901524_3	1304885.AUEY01000022_gene3406	5.919e-59	211.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MHNG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158380_k127_4901524_1	1232410.KI421413_gene669	2.261e-69	244.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158380_k127_4901524_6	682795.AciX8_4485	8.81e-15	77.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria,2JJWG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158380_k127_4901524_2	234267.Acid_5454	1.015e-59	216.0	COG0511@1|root,COG1413@1|root,COG0511@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	pcmV	-	2.3.1.12	ko:K00627,ko:K02160,ko:K07402	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,MDMPI_C,MDMPI_N,XdhC_C,XdhC_CoxI
SRR25158380_k127_4901524_4	234267.Acid_3885	1.586e-51	184.0	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	rnfB	-	1.8.99.2	ko:K00395,ko:K02572,ko:K03616	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_4,Fer4_7
SRR25158380_k127_4901524_7	761193.Runsl_2645	6.702e-05	53.0	2DIFQ@1|root,30348@2|Bacteria,4NNAK@976|Bacteroidetes,47PM1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4901524_0	251221.35213042	2.259e-171	557.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158380_k127_4905926_2	264462.Bd3531	7.465e-145	479.0	COG0397@1|root,COG0397@2|Bacteria,1NRW9@1224|Proteobacteria,42Y88@68525|delta/epsilon subdivisions,2MTGI@213481|Bdellovibrionales,2WTM9@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4905926_1	886293.Sinac_1268	2.782e-315	984.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
SRR25158380_k127_4905926_0	234267.Acid_5873	0.0	1056.0	COG3250@1|root,COG3250@2|Bacteria,3Y3BG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_49101_1	1191523.MROS_1419	2.152e-45	172.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_49101_2	1123248.KB893385_gene4832	1.079e-23	107.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1IPR4@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158380_k127_49101_0	1267535.KB906767_gene3786	1.424e-184	586.0	COG0046@1|root,COG0046@2|Bacteria,3Y30N@57723|Acidobacteria,2JHYK@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_4922399_8	1406840.Q763_11090	0.0001622	51.0	COG0457@1|root,COG0457@2|Bacteria,4NHAB@976|Bacteroidetes,1IJ6X@117743|Flavobacteriia,2NVCN@237|Flavobacterium	976|Bacteroidetes	U	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_8
SRR25158380_k127_4922399_0	234267.Acid_2573	6.939e-152	494.0	COG0541@1|root,COG0541@2|Bacteria,3Y3AU@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158380_k127_4922399_6	289376.THEYE_A0818	9.413e-20	91.0	COG0228@1|root,COG0228@2|Bacteria,3J0UI@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158380_k127_4922399_7	96561.Dole_2308	8.836e-16	79.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MKI6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158380_k127_4922399_5	1267533.KB906735_gene4712	1.68e-23	108.0	COG0806@1|root,COG0806@2|Bacteria,3Y51G@57723|Acidobacteria,2JJGA@204432|Acidobacteriia	204432|Acidobacteriia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158380_k127_4922399_2	926569.ANT_28060	2.71e-82	280.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158380_k127_4922399_4	1267535.KB906767_gene3059	6.706e-41	154.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria,2JJ9V@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158380_k127_4922399_3	765420.OSCT_1804	6.55e-81	283.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4922399_1	760568.Desku_2097	5.504e-116	381.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,265TC@186807|Peptococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4937341_1	1267533.KB906735_gene5103	2.727e-116	380.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158380_k127_4937341_5	264732.Moth_2432	7.392e-73	251.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158380_k127_4937341_13	118005.AWNK01000005_gene1580	8.498e-47	172.0	COG0100@1|root,COG0100@2|Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158380_k127_4937341_11	234267.Acid_5093	2.88e-51	184.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria	57723|Acidobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158380_k127_4937341_23	234267.Acid_5094	7.145e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,3Y5X6@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158380_k127_4937341_17	401053.AciPR4_3213	4.427e-32	125.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria,2JJUQ@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158380_k127_4937341_2	401526.TcarDRAFT_1018	2.54e-95	318.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158380_k127_4937341_8	1484479.DI14_11465	2.482e-60	216.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3WDVQ@539002|Bacillales incertae sedis	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158380_k127_4937341_0	1340493.JNIF01000003_gene3227	2.597e-160	518.0	COG0201@1|root,COG0201@2|Bacteria,3Y38D@57723|Acidobacteria	57723|Acidobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158380_k127_4937341_14	273068.TTE2273	4.003e-42	161.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158380_k127_4937341_22	240015.ACP_1433	5.15e-17	82.0	COG1841@1|root,COG1841@2|Bacteria,3Y5I2@57723|Acidobacteria,2JJZB@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158380_k127_4937341_7	720554.Clocl_3878	9.432e-62	216.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158380_k127_4937341_15	1340493.JNIF01000003_gene3223	2.686e-40	153.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria	57723|Acidobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158380_k127_4937341_9	1267533.KB906735_gene5115	1.308e-54	197.0	COG0097@1|root,COG0097@2|Bacteria,3Y496@57723|Acidobacteria,2JJ4H@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158380_k127_4937341_12	1340493.JNIF01000003_gene3221	1.398e-50	182.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158380_k127_4937341_20	1329516.JPST01000061_gene1720	1.544e-25	106.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,27CBW@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal protein S14p/S29e	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158380_k127_4937341_4	404589.Anae109_1923	8.88e-84	282.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2YURE@29|Myxococcales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158380_k127_4937341_18	1089548.KI783301_gene3361	1.979e-27	114.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3WEZB@539002|Bacillales incertae sedis	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158380_k127_4937341_10	401053.AciPR4_3226	1.586e-51	184.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158380_k127_4937341_21	1121430.JMLG01000033_gene1340	5.206e-20	93.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,262K7@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158380_k127_4937341_24	682795.AciX8_0581	1.181e-06	53.0	COG0255@1|root,COG0255@2|Bacteria,3Y5KD@57723|Acidobacteria,2JK2D@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158380_k127_4937341_6	445971.ANASTE_02056	2.414e-66	228.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,25W3Z@186806|Eubacteriaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158380_k127_4937341_3	234267.Acid_5112	2.753e-92	310.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158380_k127_4937341_19	1121920.AUAU01000010_gene98	1e-25	114.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria	57723|Acidobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158380_k127_4937341_16	290397.Adeh_1942	3.387e-34	134.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2YVJ3@29|Myxococcales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158380_k127_4940417_0	1499967.BAYZ01000095_gene4135	9.079e-157	505.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158380_k127_4940417_1	1254432.SCE1572_15915	1.709e-75	259.0	COG1335@1|root,COG1335@2|Bacteria,1MZP9@1224|Proteobacteria,42SNF@68525|delta/epsilon subdivisions,2X6IF@28221|Deltaproteobacteria,2Z22A@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158380_k127_4940417_2	204669.Acid345_2058	7.251e-09	67.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158380_k127_4943271_3	1254432.SCE1572_16555	1.101e-42	164.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
SRR25158380_k127_4943271_2	1144275.COCOR_04908	3.204e-54	201.0	COG1388@1|root,COG1388@2|Bacteria,1RIPY@1224|Proteobacteria,42TD8@68525|delta/epsilon subdivisions,2WPY2@28221|Deltaproteobacteria,2Z2U1@29|Myxococcales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158380_k127_4943271_0	204669.Acid345_4221	5.394e-89	307.0	COG0787@1|root,COG0787@2|Bacteria,3Y2U3@57723|Acidobacteria,2JI6I@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158380_k127_4943271_1	591001.Acfer_0044	1.108e-68	239.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes	909932|Negativicutes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158380_k127_495241_0	234267.Acid_5940	3.696e-122	415.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_495241_1	880073.Calab_2261	1.65e-89	306.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2NNZ0@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158380_k127_4959618_8	1047013.AQSP01000138_gene1046	6.324e-10	66.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRR25158380_k127_4959618_2	391625.PPSIR1_26006	4.1e-94	338.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,434NC@68525|delta/epsilon subdivisions,2WYZN@28221|Deltaproteobacteria,2Z10G@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158380_k127_4959618_4	1210884.HG799462_gene8164	4.728e-53	198.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158380_k127_4959618_6	204669.Acid345_3995	3.433e-29	124.0	COG0558@1|root,COG0558@2|Bacteria,3Y4S5@57723|Acidobacteria,2JJ9R@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158380_k127_4959618_0	330214.NIDE1728	1.956e-257	807.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158380_k127_4959618_1	234267.Acid_7483	2.614e-113	377.0	COG0484@1|root,COG0484@2|Bacteria,3Y2XW@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_4959618_5	1267533.KB906736_gene1388	4.942e-36	141.0	COG0789@1|root,COG0789@2|Bacteria,3Y4KX@57723|Acidobacteria,2JJA1@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158380_k127_4959618_3	278963.ATWD01000002_gene555	1.725e-67	262.0	COG1629@1|root,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_4959618_9	1210884.HG799464_gene10700	9.616e-10	64.0	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158380_k127_4959618_7	1210884.HG799464_gene10700	2.824e-15	77.0	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158380_k127_4970375_2	1242864.D187_006941	4.017e-42	162.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324,ko:K22348,ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_4970375_1	1245469.S58_43770	5.451e-107	360.0	COG1944@1|root,COG1944@2|Bacteria,1N5NV@1224|Proteobacteria,2U1QX@28211|Alphaproteobacteria,3K11H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
SRR25158380_k127_4970375_0	1245469.S58_43800	4.172e-139	451.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2TR2N@28211|Alphaproteobacteria,3JW79@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158380_k127_4972980_4	1279009.ADICEAN_02616	0.0004185	44.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158380_k127_4972980_0	1121396.KB893112_gene1933	2.584e-115	401.0	COG2366@1|root,COG2366@2|Bacteria,1R9UG@1224|Proteobacteria,42PRB@68525|delta/epsilon subdivisions,2WJCS@28221|Deltaproteobacteria,2MHYM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158380_k127_4972980_2	285535.JOEY01000033_gene9340	2.442e-32	132.0	2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_4972980_1	485913.Krac_2500	8.118e-53	202.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
SRR25158380_k127_4972980_3	596154.Alide2_1460	2.212e-09	66.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,4A9Q7@80864|Comamonadaceae	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158380_k127_4979794_3	591158.SSMG_06203	2.403e-08	55.0	COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158380_k127_4979794_2	1003195.SCAT_0389	2.41e-17	83.0	COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158380_k127_4979794_1	491205.JARQ01000006_gene2674	1.32e-69	255.0	COG2304@1|root,COG2304@2|Bacteria,4NIM2@976|Bacteroidetes	976|Bacteroidetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SRR25158380_k127_4979794_0	1232410.KI421413_gene633	1.241e-92	306.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,42QWQ@68525|delta/epsilon subdivisions,2WMRI@28221|Deltaproteobacteria,43T93@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5005928_0	383381.EH30_09290	8.753e-83	282.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2U38P@28211|Alphaproteobacteria,2K37I@204457|Sphingomonadales	204457|Sphingomonadales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
SRR25158380_k127_5005928_1	502025.Hoch_4311	3.648e-22	101.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158380_k127_5005928_3	1403313.AXBR01000005_gene1810	4.161e-09	68.0	COG0501@1|root,COG0501@2|Bacteria,1V4KK@1239|Firmicutes,4HH1T@91061|Bacilli,1ZHQ3@1386|Bacillus	91061|Bacilli	O	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M56
SRR25158380_k127_5005928_4	1379270.AUXF01000001_gene2702	1.204e-08	62.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SRR25158380_k127_5005928_2	379066.GAU_2789	4.49e-10	66.0	COG1538@1|root,COG1538@2|Bacteria,1ZV8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158380_k127_5009018_1	909663.KI867150_gene69	1.506e-55	200.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5009018_0	671143.DAMO_1138	0.0	1188.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdxB	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158380_k127_5020121_4	1118057.CAGX01000056_gene42	7.156e-51	191.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,22GK6@1570339|Peptoniphilaceae	186801|Clostridia	I	cog cog1924	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158380_k127_5020121_2	398767.Glov_2399	5.413e-77	266.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158380_k127_5020121_1	316057.RPD_1537	1.27e-89	310.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRR25158380_k127_5020121_0	648757.Rvan_0037	1.65e-92	318.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRR25158380_k127_5020121_3	562970.Btus_1277	1.846e-63	227.0	COG1028@1|root,COG1028@2|Bacteria,1TR8Y@1239|Firmicutes,4HFAC@91061|Bacilli,279AR@186823|Alicyclobacillaceae	91061|Bacilli	IQ	NAD dependent epimerase/dehydratase family	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_5026600_0	1128427.KB904821_gene3359	1.882e-78	273.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1H7FT@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Nucleos_tra2_C,Nucleos_tra2_N
SRR25158380_k127_5026600_1	700598.Niako_0775	5.751e-21	107.0	COG3325@1|root,COG3469@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes	976|Bacteroidetes	G	Glycoside Hydrolase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
SRR25158380_k127_5028283_2	247490.KSU1_B0437	8.817e-20	98.0	COG5553@1|root,COG5553@2|Bacteria	2|Bacteria	-	-	cdoA	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I,Methyltransf_11
SRR25158380_k127_5028283_0	204669.Acid345_1043	1.669e-69	252.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria,2JID2@204432|Acidobacteriia	204432|Acidobacteriia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158380_k127_5028283_1	667014.Thein_0793	7.847e-63	220.0	COG1674@1|root,COG1674@2|Bacteria,2GHMR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158380_k127_5045018_6	1173026.Glo7428_4658	7.939e-69	242.0	arCOG10178@1|root,2ZAAA@2|Bacteria,1G4AM@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158380_k127_5045018_2	1382359.JIAL01000001_gene1320	5.846e-236	744.0	COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria,2JMD8@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_5045018_3	1382359.JIAL01000001_gene1321	3.263e-111	365.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
SRR25158380_k127_5045018_1	1382359.JIAL01000001_gene1322	2.605e-297	922.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
SRR25158380_k127_5045018_0	1382359.JIAL01000001_gene1323	0.0	1367.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_5045018_4	215803.DB30_3003	5.836e-89	302.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,42QVC@68525|delta/epsilon subdivisions,2WMRZ@28221|Deltaproteobacteria,2Z33K@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	BPD_transp_1
SRR25158380_k127_5045018_5	1303518.CCALI_02440	5.461e-80	273.0	COG1116@1|root,COG1116@2|Bacteria	2|Bacteria	P	anion transmembrane transporter activity	tauB	-	-	ko:K02049,ko:K15555,ko:K15558	ko00920,ko02010,map00920,map02010	M00188,M00436,M00437	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2,3.A.1.17.5	-	-	ABC_tran
SRR25158380_k127_5045018_7	1303518.CCALI_02439	4.614e-17	84.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	ssuA	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158380_k127_5048962_1	1996.JOFO01000019_gene5254	8.844e-16	82.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4EH3M@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_5048962_0	518766.Rmar_2028	2.74e-101	359.0	COG0457@1|root,COG3829@1|root,COG0457@2|Bacteria,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1FIME@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158380_k127_506011_2	1267533.KB906733_gene3397	5.524e-30	131.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158380_k127_506011_1	1267535.KB906767_gene3770	1.137e-72	251.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_506011_0	266117.Rxyl_2946	8.255e-94	331.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158380_k127_5062260_3	391587.KAOT1_14752	1.978e-11	67.0	2CHAC@1|root,2Z7QK@2|Bacteria,4NKKS@976|Bacteroidetes,1HXFF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5062260_1	234267.Acid_1724	4.407e-101	345.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_5062260_2	204669.Acid345_4377	2.827e-91	314.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JM41@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_5062260_0	886293.Sinac_1023	1.451e-143	463.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
SRR25158380_k127_5062881_3	457570.Nther_2188	7.452e-53	208.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158380_k127_5062881_0	1128427.KB904821_gene3559	5.626e-95	320.0	COG1600@1|root,COG1600@2|Bacteria,1G007@1117|Cyanobacteria,1H7UP@1150|Oscillatoriales	1117|Cyanobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRR25158380_k127_5062881_7	1267533.KB906734_gene4367	3.92e-07	59.0	2EKP5@1|root,33ECX@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_5062881_6	1123393.KB891327_gene316	1.32e-07	63.0	2E5C5@1|root,33046@2|Bacteria,1NNAA@1224|Proteobacteria,2W6KD@28216|Betaproteobacteria,1KT4P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_5062881_1	671143.DAMO_2498	3.913e-90	300.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_5062881_4	671143.DAMO_2498	1.756e-49	181.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_5062881_2	1268239.PALB_29710	4.366e-54	197.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,2Q13K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158380_k127_5062881_5	1463820.JOGW01000016_gene5095	5.84e-12	76.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158380_k127_5062881_8	195250.CM001776_gene4053	2.092e-06	49.0	COG1595@1|root,COG1595@2|Bacteria,1G34M@1117|Cyanobacteria,1H1C3@1129|Synechococcus	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_5065659_0	1267533.KB906735_gene4448	3.639e-140	465.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SRR25158380_k127_5065659_2	644282.Deba_0928	3.072e-18	87.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158380_k127_5065659_3	1397528.Q671_04295	9.138e-12	73.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XKTT@135619|Oceanospirillales	135619|Oceanospirillales	S	Integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158380_k127_5065659_1	439235.Dalk_0394	8.676e-61	218.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158380_k127_5069930_6	204669.Acid345_1660	4.512e-30	138.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
SRR25158380_k127_5069930_2	1121007.AUML01000008_gene999	1.011e-93	315.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia,2YI3J@290174|Aquimarina	976|Bacteroidetes	S	ATPases associated with a variety of cellular activities	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158380_k127_5069930_1	234267.Acid_7397	2.833e-104	358.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158380_k127_5069930_4	671143.DAMO_1191	1.37e-30	128.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
SRR25158380_k127_5069930_3	671143.DAMO_1192	1.916e-76	267.0	COG1660@1|root,COG1660@2|Bacteria,2NP9G@2323|unclassified Bacteria	2|Bacteria	S	P-loop ATPase protein family	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158380_k127_5069930_5	1047013.AQSP01000135_gene1606	3.446e-30	125.0	COG2893@1|root,COG2893@2|Bacteria,2NRCX@2323|unclassified Bacteria	2|Bacteria	G	PTS system fructose IIA component	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
SRR25158380_k127_5069930_0	243231.GSU1881	1.247e-113	391.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,43TR7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
SRR25158380_k127_5069930_8	316056.RPC_4223	0.0001823	50.0	2DIBV@1|root,302PB@2|Bacteria,1Q8HI@1224|Proteobacteria,2UW8G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5069930_7	1121396.KB893074_gene3015	2.201e-05	54.0	COG1266@1|root,COG1266@2|Bacteria,1NHU2@1224|Proteobacteria,42ZSH@68525|delta/epsilon subdivisions,2WUV3@28221|Deltaproteobacteria,2MNAH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158380_k127_5079220_3	926569.ANT_13580	9.319e-12	66.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_5079220_0	1121920.AUAU01000018_gene1783	3.604e-289	903.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_5079220_4	1267533.KB906741_gene641	3.728e-09	63.0	COG4319@1|root,COG4319@2|Bacteria,3Y5EF@57723|Acidobacteria,2JJP7@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_5079220_2	204669.Acid345_3238	5.596e-35	135.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	MA20_26500	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158380_k127_5079220_1	204669.Acid345_3237	2.912e-42	156.0	2EQP8@1|root,33I96@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5102941_5	234267.Acid_0913	4.05e-57	206.0	COG0321@1|root,COG0321@2|Bacteria,3Y448@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
SRR25158380_k127_5102941_1	997346.HMPREF9374_3051	3.027e-104	347.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,27BPA@186824|Thermoactinomycetaceae	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_5102941_6	1123508.JH636440_gene2560	1.934e-30	124.0	2BYEG@1|root,349F2@2|Bacteria,2J42U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5102941_3	1123508.JH636440_gene2559	2.098e-72	257.0	2EZN7@1|root,33ST8@2|Bacteria,2J2CB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5102941_2	1121920.AUAU01000012_gene2645	3.73e-102	340.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_5102941_7	1340493.JNIF01000003_gene1547	9.581e-20	98.0	2D4UK@1|root,32THN@2|Bacteria,3Y59Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142
SRR25158380_k127_5102941_4	204669.Acid345_4530	9.384e-66	254.0	COG4805@1|root,COG4805@2|Bacteria,3Y4PP@57723|Acidobacteria,2JKV8@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5102941_0	215803.DB30_6786	1.609e-121	399.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_5107729_0	1121405.dsmv_2717	1.315e-263	825.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158380_k127_5107729_3	671143.DAMO_2768	2.542e-41	159.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158380_k127_5107729_2	215803.DB30_3013	2.306e-59	224.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SRR25158380_k127_5107729_1	525904.Tter_2339	3.99e-137	447.0	COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria	2|Bacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
SRR25158380_k127_5108461_1	1006004.GBAG_2433	4.156e-68	239.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	(ABC) transporter	yecC	GO:0000099,GO:0000101,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363,GO:1901682,GO:1902475,GO:1903825,GO:1905039	3.6.3.21	ko:K02028,ko:K02029,ko:K10010	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
SRR25158380_k127_5108461_0	247490.KSU1_D0644	5.425e-114	385.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,2IY5R@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
SRR25158380_k127_5110293_7	234267.Acid_5690	4.461e-05	47.0	COG1007@1|root,COG1007@2|Bacteria,3Y43Y@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158380_k127_5110293_1	743836.AYNA01000104_gene2059	3.684e-61	226.0	COG1215@1|root,COG1215@2|Bacteria,1R8UT@1224|Proteobacteria,2TVQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
SRR25158380_k127_5110293_0	435591.BDI_3207	1.453e-71	255.0	COG0535@1|root,COG0535@2|Bacteria,4PA9R@976|Bacteroidetes,2FWDR@200643|Bacteroidia	976|Bacteroidetes	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
SRR25158380_k127_5110293_5	136993.KB900626_gene3331	8.214e-07	53.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,36YZH@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158380_k127_5110293_3	1340493.JNIF01000003_gene3632	1.677e-45	177.0	COG0356@1|root,COG0356@2|Bacteria,3Y4CM@57723|Acidobacteria	57723|Acidobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158380_k127_5110293_4	448385.sce7980	3.676e-12	71.0	COG0636@1|root,COG0636@2|Bacteria,1QAIF@1224|Proteobacteria,43A8Y@68525|delta/epsilon subdivisions,2X9Z1@28221|Deltaproteobacteria,2YW38@29|Myxococcales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158380_k127_5110293_2	204669.Acid345_2957	9.834e-51	184.0	COG0394@1|root,COG0394@2|Bacteria,3Y5NY@57723|Acidobacteria,2JK6K@204432|Acidobacteriia	204432|Acidobacteriia	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158380_k127_5110293_6	861299.J421_1991	1.483e-06	52.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1991|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_5112768_2	868864.Dester_1407	2.763e-19	91.0	COG1499@1|root,COG1499@2|Bacteria,2G444@200783|Aquificae	200783|Aquificae	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
SRR25158380_k127_5112768_0	297246.lpp1521	1.141e-80	276.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1RS3D@1236|Gammaproteobacteria,1JGIA@118969|Legionellales	118969|Legionellales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158380_k127_5112768_1	639030.JHVA01000001_gene3668	1.133e-63	223.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y950@57723|Acidobacteria	57723|Acidobacteria	G	PEP-utilising enzyme, mobile domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158380_k127_5113101_0	1267533.KB906733_gene3489	5.9e-115	381.0	COG0189@1|root,COG0189@2|Bacteria,3Y37D@57723|Acidobacteria,2JI05@204432|Acidobacteriia	204432|Acidobacteriia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5116476_2	251221.35213191	2.155e-79	271.0	COG1429@1|root,COG1429@2|Bacteria,1G0W1@1117|Cyanobacteria	1117|Cyanobacteria	H	magnesium chelatase, H subunit	chlH	-	6.6.1.1	ko:K03403	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,DUF3479
SRR25158380_k127_5116476_5	234267.Acid_4806	3.743e-14	79.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF836,Thioredoxin,Thioredoxin_3
SRR25158380_k127_5116476_3	234267.Acid_4388	3.548e-61	217.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158380_k127_5116476_0	234267.Acid_4387	3.985e-146	468.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR25158380_k127_5116476_1	234267.Acid_4386	4.369e-133	433.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158380_k127_5116476_4	234267.Acid_4385	1.411e-50	193.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
SRR25158380_k127_5118673_0	204669.Acid345_2713	2.972e-173	565.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
SRR25158380_k127_5118673_1	204669.Acid345_2712	7.897e-126	415.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SRR25158380_k127_5128074_4	269798.CHU_3752	4.005e-08	59.0	COG0729@1|root,COG1409@1|root,COG0729@2|Bacteria,COG1409@2|Bacteria,4PM2S@976|Bacteroidetes,47Y0P@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
SRR25158380_k127_5128074_3	742818.HMPREF9451_01764	8.154e-13	76.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CUEF@84998|Coriobacteriia	84998|Coriobacteriia	O	DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158380_k127_5128074_2	234267.Acid_7940	8.518e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,3Y5K8@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_5128074_5	234267.Acid_7938	1.052e-07	62.0	291QZ@1|root,2ZPB0@2|Bacteria,3Y92F@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5128074_0	870187.Thini_1988	4.989e-72	257.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,DUF2510,PknH_C,TIR_2
SRR25158380_k127_5128074_1	1267535.KB906767_gene277	1.825e-58	207.0	2DB97@1|root,33TRP@2|Bacteria,3Y7NY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_51488_4	485913.Krac_5984	2.99e-36	154.0	COG3115@1|root,COG3115@2|Bacteria	2|Bacteria	D	cell septum assembly	-	-	-	ko:K02487,ko:K06596,ko:K08372	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko02022,ko02035	-	-	-	FliO,SPOR,ZipA_C
SRR25158380_k127_51488_0	1079986.JH164874_gene2947	3.942e-104	343.0	COG4312@1|root,COG4312@2|Bacteria,2H9QT@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158380_k127_51488_1	243231.GSU2326	5.315e-51	188.0	COG3040@1|root,COG3040@2|Bacteria,1RIHP@1224|Proteobacteria,42SSW@68525|delta/epsilon subdivisions,2X6M9@28221|Deltaproteobacteria,43VBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
SRR25158380_k127_51488_3	234831.PSM_A1680	7.037e-45	167.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,2Q18Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158380_k127_51488_2	1123242.JH636434_gene5321	3.583e-46	173.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158380_k127_52066_2	335659.S23_47990	4.857e-05	56.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria,3JQN5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	HEAT repeat	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158380_k127_52066_3	330214.NIDE1600	0.0001341	55.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,PT-HINT,RHS_repeat
SRR25158380_k127_52066_0	247490.KSU1_D1057	2.197e-14	87.0	COG0457@1|root,COG0457@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158380_k127_52066_4	316274.Haur_0378	0.0001567	53.0	COG0745@1|root,COG0745@2|Bacteria,2GBPZ@200795|Chloroflexi,375YS@32061|Chloroflexia	32061|Chloroflexia	KT	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158380_k127_52066_1	953739.SVEN_2491	2.36e-10	73.0	2EBSJ@1|root,335SE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_531292_0	234267.Acid_5012	3.657e-141	453.0	COG0008@1|root,COG0008@2|Bacteria,3Y7DS@57723|Acidobacteria	57723|Acidobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
SRR25158380_k127_531292_2	1392488.JHZY01000002_gene366	3.02e-06	60.0	COG5295@1|root,COG5295@2|Bacteria,4NN7P@976|Bacteroidetes,1I1GH@117743|Flavobacteriia,2XJCX@283735|Leeuwenhoekiella	976|Bacteroidetes	UW	Head domain of trimeric autotransporter adhesin	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_head
SRR25158380_k127_531292_1	945713.IALB_2758	6.379e-36	139.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_541220_1	748247.AZKH_2015	9.115e-38	147.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2VVJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158380_k127_541220_0	105422.BBPM01000038_gene930	1.047e-55	202.0	COG1388@1|root,COG1388@2|Bacteria,2IKMC@201174|Actinobacteria	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_541220_2	234267.Acid_2401	4.46e-26	108.0	COG1398@1|root,COG1398@2|Bacteria,3Y6GE@57723|Acidobacteria	57723|Acidobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158380_k127_552520_1	1386089.N865_16170	4.382e-32	129.0	COG2333@1|root,COG2333@2|Bacteria,2GNIE@201174|Actinobacteria,4FIWP@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_552520_3	1453505.JASY01000029_gene337	1.483e-06	52.0	2DBKD@1|root,2Z9SP@2|Bacteria,4P4SR@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4263
SRR25158380_k127_552520_2	1047013.AQSP01000139_gene2325	4.796e-16	90.0	COG3595@1|root,COG3595@2|Bacteria,2NQ1F@2323|unclassified Bacteria	2|Bacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158380_k127_552520_4	497964.CfE428DRAFT_4051	1.266e-05	56.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158380_k127_552520_0	1242864.D187_002705	3.506e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42URE@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_552520_5	227086.JGI_V11_18628	0.0004026	45.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	SPY	GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377	-	ko:K10408	ko05016,map05016	-	-	-	ko00000,ko00001,ko04812	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_8
SRR25158380_k127_558984_7	1195246.AGRI_14810	7.745e-05	55.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria,1SGXT@1236|Gammaproteobacteria,46C5U@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	PilX N-terminal	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
SRR25158380_k127_558984_1	204669.Acid345_1588	2.183e-156	507.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JKV3@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_558984_0	234267.Acid_1531	1.237e-191	615.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158380_k127_558984_2	671143.DAMO_1556	1.552e-102	355.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158380_k127_558984_5	926692.AZYG01000040_gene1499	2.111e-24	108.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WASM@53433|Halanaerobiales	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158380_k127_558984_3	861299.J421_2070	2.051e-54	194.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
SRR25158380_k127_558984_4	211165.AJLN01000116_gene3257	2.869e-31	127.0	2CIIF@1|root,315FB@2|Bacteria,1G6R8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_562121_2	1123368.AUIS01000020_gene1108	2.834e-35	139.0	COG5592@1|root,COG5592@2|Bacteria,1RGUY@1224|Proteobacteria,1S5V6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hemerythrin hhe cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158380_k127_562121_0	251221.35213742	5.596e-101	345.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_562121_3	1379270.AUXF01000002_gene1475	6.772e-06	52.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1ZTAG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158380_k127_562121_1	880073.Calab_0552	4.874e-38	146.0	2AFHA@1|root,315HT@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_572690_2	1121405.dsmv_0655	2.972e-74	253.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,42MX4@68525|delta/epsilon subdivisions,2WKVB@28221|Deltaproteobacteria,2MHKN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
SRR25158380_k127_572690_1	330214.NIDE3564	4.838e-91	334.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
SRR25158380_k127_572690_0	204669.Acid345_3921	1.899e-159	515.0	COG0146@1|root,COG0146@2|Bacteria,3Y6W2@57723|Acidobacteria,2JKCE@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158380_k127_582337_0	765420.OSCT_1210	1.66e-150	486.0	COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,376YS@32061|Chloroflexia	32061|Chloroflexia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158380_k127_582337_2	644107.SL1157_0226	1.444e-80	274.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,4NBU3@97050|Ruegeria	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158380_k127_582337_1	234267.Acid_1869	3.603e-137	445.0	COG0031@1|root,COG0031@2|Bacteria,3Y71B@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_59302_1	926562.Oweho_0729	1.835e-09	61.0	2EX72@1|root,33QHY@2|Bacteria,4P0XX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_59302_0	926562.Oweho_0730	0.0	1280.0	2EWXC@1|root,33Q8R@2|Bacteria,4P0K7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_596885_1	639030.JHVA01000001_gene673	1.139e-06	57.0	2A9J8@1|root,30YRM@2|Bacteria,3Y4IZ@57723|Acidobacteria,2JJDB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_597039_2	1173027.Mic7113_5049	2.413e-161	529.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158380_k127_597039_8	945713.IALB_0838	1.444e-63	224.0	COG1435@1|root,COG1435@2|Bacteria	2|Bacteria	F	thymidine kinase activity	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
SRR25158380_k127_597039_19	911045.PSE_3616	5.775e-10	67.0	COG1986@1|root,COG1986@2|Bacteria,1R60T@1224|Proteobacteria	1224|Proteobacteria	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	iECO111_1330.ECO111_5255	NTPase_I-T
SRR25158380_k127_597039_3	1379698.RBG1_1C00001G0513	8.964e-146	472.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158380_k127_597039_5	1273538.G159_13155	2.774e-96	329.0	COG0624@1|root,COG0624@2|Bacteria,1TYR6@1239|Firmicutes,4HCVC@91061|Bacilli,26GUX@186818|Planococcaceae	91061|Bacilli	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158380_k127_597039_20	880073.Calab_3013	1.385e-08	66.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
SRR25158380_k127_597039_21	330214.NIDE1600	6.594e-07	61.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,PT-HINT,RHS_repeat
SRR25158380_k127_597039_15	1191523.MROS_0347	1.323e-30	134.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158380_k127_597039_18	118168.MC7420_6983	4.681e-15	85.0	29WN8@1|root,30I93@2|Bacteria,1GAIY@1117|Cyanobacteria	1117|Cyanobacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
SRR25158380_k127_597039_1	1089553.Tph_c06770	8.563e-184	587.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,42FP5@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158380_k127_597039_12	306281.AJLK01000103_gene3365	1.124e-47	176.0	COG0454@1|root,COG0454@2|Bacteria,1G5EA@1117|Cyanobacteria,1JMBB@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SRR25158380_k127_597039_0	889378.Spiaf_0670	3.104e-193	611.0	COG0148@1|root,COG0148@2|Bacteria,2J59Y@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158380_k127_597039_4	525897.Dbac_2296	1.005e-135	446.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2M7ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Transporter-associated region	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158380_k127_597039_13	204669.Acid345_0553	1.752e-37	149.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158380_k127_597039_22	234267.Acid_2699	0.0005267	53.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AhpC-TSA,CarboxypepD_reg,PDZ_2,Plug,TonB_dep_Rec
SRR25158380_k127_597039_16	234267.Acid_1525	1.331e-24	119.0	COG4932@1|root,COG4932@2|Bacteria,3Y53F@57723|Acidobacteria	57723|Acidobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_597039_6	391625.PPSIR1_34013	8.188e-81	290.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1R45Z@1224|Proteobacteria,43AMH@68525|delta/epsilon subdivisions,2X61H@28221|Deltaproteobacteria,2Z38T@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
SRR25158380_k127_597039_7	429009.Adeg_1540	1.67e-77	272.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,42EXB@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158380_k127_597039_11	243164.DET0769	5.034e-52	198.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,34D00@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158380_k127_597039_9	204669.Acid345_0278	2.751e-57	210.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
SRR25158380_k127_597039_17	1232410.KI421415_gene3037	1.076e-19	100.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,43SGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158380_k127_597039_14	1489678.RDMS_07835	3.666e-36	143.0	COG1109@1|root,COG1109@2|Bacteria,1WITP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_615821_2	1042877.GQS_06310	1.056e-28	119.0	COG1071@1|root,arCOG01054@2157|Archaea,2XV79@28890|Euryarchaeota,244ZD@183968|Thermococci	183968|Thermococci	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
SRR25158380_k127_615821_0	234267.Acid_0353	9.298e-134	434.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158380_k127_615821_1	1121920.AUAU01000004_gene789	4.378e-116	390.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158380_k127_624591_8	1123256.KB907930_gene3511	1.261e-40	156.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1X38K@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158380_k127_624591_2	1121468.AUBR01000026_gene2918	1.083e-98	334.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158380_k127_624591_1	1267535.KB906767_gene4183	2.238e-105	356.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158380_k127_624591_3	204669.Acid345_3335	9.183e-98	342.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158380_k127_624591_9	696281.Desru_0749	9.261e-31	129.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,266VX@186807|Peptococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_624591_5	401053.AciPR4_1853	5.683e-66	233.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158380_k127_624591_4	401053.AciPR4_1852	4.135e-73	256.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158380_k127_624591_7	1267533.KB906733_gene2953	2.885e-57	214.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158380_k127_624591_6	1123242.JH636436_gene744	1.114e-58	207.0	COG2318@1|root,COG2318@2|Bacteria,2IZP2@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SRR25158380_k127_624591_0	504472.Slin_5713	0.0	1321.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	GRASP55_65,PD40,PDZ_2,Peptidase_S41,Tricorn_C1
SRR25158380_k127_62604_1	1463917.JODC01000007_gene7319	8.253e-64	225.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
SRR25158380_k127_62604_0	243090.RB8505	3.753e-75	268.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158380_k127_637323_2	1045855.DSC_06015	2.279e-40	158.0	2AQ2A@1|root,31F7E@2|Bacteria,1QCMG@1224|Proteobacteria,1T8CS@1236|Gammaproteobacteria,1XAFU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_637323_1	379066.GAU_3186	5.695e-113	383.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_637323_0	192952.MM_1461	6.623e-153	488.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,2NAFK@224756|Methanomicrobia	28890|Euryarchaeota	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpA	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158380_k127_637589_1	671143.DAMO_2838	4.922e-69	254.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9P@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158380_k127_637589_0	316067.Geob_0533	7.624e-135	443.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U2Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_637589_2	1423321.AS29_21095	1.402e-24	115.0	COG3206@1|root,COG3206@2|Bacteria,1V8AX@1239|Firmicutes,4HCT2@91061|Bacilli,1ZDP1@1386|Bacillus	91061|Bacilli	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158380_k127_637589_3	1121930.AQXG01000008_gene137	7.376e-21	98.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC
SRR25158380_k127_646898_1	204669.Acid345_2506	1.614e-66	239.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158380_k127_646898_3	1382359.JIAL01000001_gene1085	4.636e-42	170.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_646898_2	1210884.HG799468_gene13886	5.121e-47	173.0	COG5478@1|root,COG5478@2|Bacteria,2J05Z@203682|Planctomycetes	203682|Planctomycetes	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRR25158380_k127_646898_4	592015.HMPREF1705_01670	2.589e-29	120.0	COG4577@1|root,COG4577@2|Bacteria,3TB6U@508458|Synergistetes	508458|Synergistetes	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
SRR25158380_k127_646898_0	555088.DealDRAFT_2073	1.673e-178	572.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,42KB8@68298|Syntrophomonadaceae	186801|Clostridia	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
SRR25158380_k127_646898_5	1121472.AQWN01000002_gene2136	3.052e-18	90.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,262HN@186807|Peptococcaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
SRR25158380_k127_647195_1	204669.Acid345_0907	5.775e-141	455.0	COG4213@1|root,COG4213@2|Bacteria	2|Bacteria	G	D-xylose transmembrane transport	xylF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	iB21_1397.B21_03369,iECBD_1354.ECBD_0168,iECD_1391.ECD_03418,iEcHS_1320.EcHS_A3769,iEcolC_1368.EcolC_0148,iUTI89_1310.UTI89_C4107,ic_1306.c4386	Peripla_BP_4
SRR25158380_k127_647195_0	264732.Moth_2021	4.024e-177	569.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42ESS@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system	xylG	-	3.6.3.17	ko:K10441,ko:K10545	ko02010,map02010	M00212,M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4	-	-	ABC_tran
SRR25158380_k127_647195_2	204669.Acid345_0905	5.298e-118	391.0	COG4214@1|root,COG4214@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR25158380_k127_652241_1	1499967.BAYZ01000182_gene4451	1.987e-135	444.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_652241_0	251221.35211765	1.579e-175	578.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_652241_2	91464.S7335_962	2.36e-35	138.0	COG3654@1|root,COG3654@2|Bacteria,1G71M@1117|Cyanobacteria,1H2A1@1129|Synechococcus	1117|Cyanobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158380_k127_661084_5	1203556.HMPREF1478_00554	2.631e-05	57.0	COG1470@1|root,COG2373@1|root,COG4932@1|root,COG1470@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,2I66Z@201174|Actinobacteria,4D38B@85005|Actinomycetales	201174|Actinobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SRR25158380_k127_661084_4	204669.Acid345_2015	4.955e-31	132.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158380_k127_661084_2	335543.Sfum_0112	9.049e-73	253.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,42SJ9@68525|delta/epsilon subdivisions,2WPBC@28221|Deltaproteobacteria,2MRQE@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_661084_3	1132855.KB913035_gene1502	6.692e-36	143.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
SRR25158380_k127_661084_1	589865.DaAHT2_0467	2.937e-109	368.0	COG0477@1|root,COG2814@2|Bacteria,1QW2F@1224|Proteobacteria,43BTU@68525|delta/epsilon subdivisions,2X74Q@28221|Deltaproteobacteria,2MKZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158380_k127_661084_0	1340493.JNIF01000003_gene4593	6.995e-111	383.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158380_k127_661668_1	1382359.JIAL01000001_gene2101	4.792e-111	366.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158380_k127_661668_0	204669.Acid345_1757	2.696e-131	444.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158380_k127_662502_0	1408473.JHXO01000008_gene2711	6.4e-290	906.0	COG1472@1|root,COG1472@2|Bacteria,4NEBU@976|Bacteroidetes,2FN0J@200643|Bacteroidia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_662502_1	1267535.KB906767_gene3020	1.426e-205	649.0	COG0457@1|root,COG0457@2|Bacteria,3Y3WM@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158380_k127_663112_0	661478.OP10G_4632	1.119e-115	391.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158380_k127_663112_1	582515.KR51_00025710	8.594e-19	88.0	2EUSR@1|root,33N8A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_664030_3	391600.ABRU01000056_gene546	2.678e-54	202.0	COG1235@1|root,COG2333@1|root,COG1235@2|Bacteria,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria,2U6NT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_664030_1	1380387.JADM01000004_gene2910	5.178e-79	284.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1XH4D@135619|Oceanospirillales	135619|Oceanospirillales	E	GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158380_k127_664030_2	234267.Acid_3624	1.274e-74	277.0	2F78B@1|root,33ZPK@2|Bacteria,3Y85N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_664030_4	234267.Acid_6739	1.989e-47	175.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
SRR25158380_k127_664030_6	234267.Acid_6739	2.807e-06	51.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
SRR25158380_k127_664030_5	234267.Acid_6099	1.34e-13	72.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
SRR25158380_k127_664030_0	1408473.JHXO01000011_gene3116	3.661e-131	426.0	COG3938@1|root,COG3938@2|Bacteria,4NJMD@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158380_k127_673098_2	1267533.KB906733_gene3398	1.397e-18	100.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_673098_0	204669.Acid345_0689	5.453e-141	459.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158380_k127_673098_1	1379698.RBG1_1C00001G1345	3.639e-87	298.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
SRR25158380_k127_673540_1	324925.Ppha_2590	7.439e-61	224.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158380_k127_673540_2	485913.Krac_12159	5.811e-14	79.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
SRR25158380_k127_673540_0	240015.ACP_0923	4.354e-191	621.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria,2JI7G@204432|Acidobacteriia	204432|Acidobacteriia	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
SRR25158380_k127_689712_0	240015.ACP_1017	6.251e-51	190.0	COG1183@1|root,COG1183@2|Bacteria,3Y3I7@57723|Acidobacteria,2JIEG@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158380_k127_689712_1	289376.THEYE_A0652	2.299e-45	171.0	COG0688@1|root,COG0688@2|Bacteria,3J0KD@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158380_k127_689712_3	204669.Acid345_2361	4.685e-07	54.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria,2JNW9@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
SRR25158380_k127_689712_2	246194.CHY_0724	6.941e-20	95.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158380_k127_692719_0	1047013.AQSP01000131_gene1797	1.739e-38	162.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158380_k127_692719_2	1122138.AQUZ01000019_gene8171	9.643e-16	91.0	COG1520@1|root,COG4733@1|root,COG1520@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,PQQ_2,SLH
SRR25158380_k127_692719_1	545694.TREPR_2517	1.122e-18	100.0	COG0457@1|root,COG0457@2|Bacteria,2JAA8@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8
SRR25158380_k127_692719_3	575540.Isop_1665	3.025e-11	72.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
SRR25158380_k127_693128_3	1211035.CD30_10155	2.373e-24	113.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3IVQD@400634|Lysinibacillus	91061|Bacilli	L	DNA polymerase III subunit delta	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158380_k127_693128_4	401053.AciPR4_0677	1.214e-15	84.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria,2JJKB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SRR25158380_k127_693128_1	96561.Dole_3045	3.642e-80	276.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2MITP@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158380_k127_693128_0	204669.Acid345_0064	1.485e-257	809.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158380_k127_693128_2	1122221.JHVI01000004_gene206	4.825e-37	151.0	COG0037@1|root,COG0590@1|root,COG0037@2|Bacteria,COG0590@2|Bacteria,1WIEH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	DFJ	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tadA	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,MafB19-deam,TilS_C,dCMP_cyt_deam_1
SRR25158380_k127_69426_2	880073.Calab_3201	2.522e-105	352.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
SRR25158380_k127_69426_8	1279009.ADICEAN_02760	1.344e-35	141.0	COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_69426_5	266117.Rxyl_2043	2.545e-48	174.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158380_k127_69426_6	926561.KB900617_gene2105	2.327e-46	181.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,3WC93@53433|Halanaerobiales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_69426_7	883126.HMPREF9710_01170	5.792e-45	172.0	COG3861@1|root,COG4572@1|root,COG3861@2|Bacteria,COG4572@2|Bacteria,1MWBU@1224|Proteobacteria,2VR9U@28216|Betaproteobacteria,477EZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cation transport regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_69426_10	906888.JCM19314_1183	3.111e-08	57.0	COG3237@1|root,COG3237@2|Bacteria,4PDUZ@976|Bacteroidetes,1IE8H@117743|Flavobacteriia,3HM8M@363408|Nonlabens	976|Bacteroidetes	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158380_k127_69426_4	671143.DAMO_2120	5.05e-59	223.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158380_k127_69426_1	1173028.ANKO01000014_gene1000	9.993e-145	492.0	COG0784@1|root,COG3290@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158380_k127_69426_3	1089546.AQUI01000002_gene895	4.524e-102	348.0	COG0467@1|root,COG0467@2|Bacteria,2I58C@201174|Actinobacteria	201174|Actinobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158380_k127_69426_9	378806.STAUR_4296	3.617e-35	140.0	COG0745@1|root,COG0745@2|Bacteria,1P6A4@1224|Proteobacteria,4333R@68525|delta/epsilon subdivisions,2WY7A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158380_k127_69426_0	1118058.CAGY01000001_gene597	1.162e-191	610.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4D3ID@85005|Actinomycetales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158380_k127_700987_0	278963.ATWD01000001_gene2771	3.464e-63	241.0	COG1629@1|root,COG1629@2|Bacteria,3Y2FQ@57723|Acidobacteria,2JIDJ@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158380_k127_700987_2	204669.Acid345_3941	5.525e-09	67.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria,2JNRM@204432|Acidobacteriia	204432|Acidobacteriia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_700987_1	1267535.KB906767_gene2751	6.71e-11	73.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_702712_3	234267.Acid_2667	3.791e-109	355.0	COG4948@1|root,COG4948@2|Bacteria,3Y4P2@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158380_k127_702712_2	1267535.KB906767_gene3252	7.925e-147	476.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_702712_1	234267.Acid_2679	1.098e-260	826.0	COG1472@1|root,COG1472@2|Bacteria,3Y3QE@57723|Acidobacteria	57723|Acidobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_702712_0	1047013.AQSP01000113_gene740	1.289e-318	998.0	COG1472@1|root,COG1472@2|Bacteria,2NNR4@2323|unclassified Bacteria	2|Bacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158380_k127_704495_6	1267533.KB906735_gene5073	6.067e-54	207.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158380_k127_704495_4	1254432.SCE1572_26545	1.011e-73	261.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158380_k127_704495_1	1267535.KB906767_gene1118	1.569e-78	269.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158380_k127_704495_9	1089547.KB913013_gene761	7.859e-10	65.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_704495_7	861299.J421_6107	1.686e-39	151.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158380_k127_704495_3	204669.Acid345_2185	1.611e-74	259.0	COG1694@1|root,COG3956@2|Bacteria,3Y46M@57723|Acidobacteria,2JIEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM MazG family protein	-	-	3.6.1.66,3.6.1.9	ko:K02428,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRR25158380_k127_704495_8	439235.Dalk_3378	9.093e-13	75.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR25158380_k127_704495_2	204669.Acid345_2630	1.458e-75	261.0	COG1235@1|root,COG1235@2|Bacteria,3Y40S@57723|Acidobacteria,2JIH7@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SRR25158380_k127_704495_5	883.DvMF_1762	1.279e-71	253.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2M8RD@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158380_k127_704495_0	41431.PCC8801_1310	2.052e-88	307.0	COG0661@1|root,COG0661@2|Bacteria,1G1KC@1117|Cyanobacteria,3KH08@43988|Cyanothece	1117|Cyanobacteria	S	PFAM ABC-1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158380_k127_70709_1	1267534.KB906756_gene324	2.797e-85	308.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158380_k127_70709_0	204669.Acid345_4661	1.967e-205	655.0	COG0539@1|root,COG0539@2|Bacteria,3Y3DA@57723|Acidobacteria,2JHS3@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158380_k127_717991_3	1267533.KB906739_gene2758	0.0004605	44.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_717991_1	330214.NIDE3859	2.747e-29	123.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158380_k127_717991_0	234267.Acid_1869	2.264e-65	227.0	COG0031@1|root,COG0031@2|Bacteria,3Y71B@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_718228_0	1267534.KB906756_gene561	6.148e-176	568.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158380_k127_718228_1	1089550.ATTH01000001_gene2139	2.538e-171	557.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1FIQC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158380_k127_718228_2	671143.DAMO_0870	1.219e-08	66.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	ko:K03194	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	CHAP,SLT
SRR25158380_k127_719496_2	1123508.JH636439_gene798	1.458e-108	358.0	COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158380_k127_719496_1	1340493.JNIF01000003_gene3505	6.364e-117	387.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_719496_3	682795.AciX8_0649	3.061e-87	297.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria,2JIHD@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158380_k127_719496_4	234267.Acid_7127	3.983e-81	277.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria	57723|Acidobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158380_k127_719496_6	1123253.AUBD01000002_gene1318	6.175e-53	209.0	COG1075@1|root,COG1075@2|Bacteria,1PHER@1224|Proteobacteria,1T7T0@1236|Gammaproteobacteria,1X9P7@135614|Xanthomonadales	135614|Xanthomonadales	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
SRR25158380_k127_719496_5	247490.KSU1_C1161	2.764e-78	280.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	yidC	-	-	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,DUF4124,PDZ_2,Peptidase_C11,SLH,TPM_phosphatase,TPR_11,Trypsin_2,YidC_periplas
SRR25158380_k127_719496_0	290397.Adeh_3947	1.022e-215	684.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158380_k127_720666_3	1267535.KB906767_gene4113	4.298e-31	128.0	COG2940@1|root,COG2940@2|Bacteria,3Y7R1@57723|Acidobacteria	57723|Acidobacteria	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158380_k127_720666_0	1267535.KB906767_gene1506	2.156e-88	298.0	COG0689@1|root,COG0689@2|Bacteria,3Y2FP@57723|Acidobacteria,2JHM3@204432|Acidobacteriia	204432|Acidobacteriia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158380_k127_720666_1	1278073.MYSTI_06338	1.146e-72	255.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
SRR25158380_k127_720666_2	886293.Sinac_3291	2.653e-37	148.0	COG4636@1|root,COG4636@2|Bacteria,2J0XX@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158380_k127_721103_5	338963.Pcar_1323	8.374e-17	84.0	COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
SRR25158380_k127_721103_3	45157.CML204CT	1.379e-37	149.0	COG0077@1|root,KOG2797@2759|Eukaryota	2759|Eukaryota	E	arogenate dehydratase activity	-	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009642,GO:0009645,GO:0009987,GO:0010244,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0050896,GO:0071704,GO:0080167,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51,4.2.1.91	ko:K05359,ko:K20102	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	PDT
SRR25158380_k127_721103_0	204669.Acid345_3110	2.495e-140	455.0	COG2876@1|root,COG2876@2|Bacteria,3Y64W@57723|Acidobacteria,2JMIX@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158380_k127_721103_4	682795.AciX8_0081	9.401e-28	129.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,3Y6JC@57723|Acidobacteria,2JKDS@204432|Acidobacteriia	204432|Acidobacteriia	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
SRR25158380_k127_721103_2	234267.Acid_0097	2.34e-39	151.0	COG3682@1|root,COG3682@2|Bacteria,3Y57R@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158380_k127_721103_1	204669.Acid345_2902	7.019e-47	173.0	COG2197@1|root,COG2197@2|Bacteria,3Y60I@57723|Acidobacteria,2JKWI@204432|Acidobacteriia	204432|Acidobacteriia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158380_k127_742137_1	1122604.JONR01000026_gene3027	2.831e-133	439.0	COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,1S1ET@1236|Gammaproteobacteria,1X3J6@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158380_k127_742137_0	1123508.JH636444_gene5485	6.819e-157	507.0	COG0635@1|root,COG0635@2|Bacteria,2IY84@203682|Planctomycetes	203682|Planctomycetes	H	COG0635 Coproporphyrinogen III oxidase and related Fe-S	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_742137_2	314230.DSM3645_15415	1.527e-121	404.0	COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes	203682|Planctomycetes	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158380_k127_749104_6	215803.DB30_5220	2.945e-10	62.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,2YXI1@29|Myxococcales	28221|Deltaproteobacteria	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
SRR25158380_k127_749104_5	43989.cce_3960	3.079e-16	86.0	COG0745@1|root,COG0745@2|Bacteria,1G2ME@1117|Cyanobacteria,3KGZN@43988|Cyanothece	1117|Cyanobacteria	K	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_749104_3	1267535.KB906767_gene1297	2.464e-30	135.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_749104_0	886293.Sinac_6154	2.454e-193	631.0	COG2866@1|root,COG2866@2|Bacteria,2IXPH@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158380_k127_749104_2	1382359.JIAL01000001_gene1609	1.477e-36	148.0	COG0204@1|root,COG0204@2|Bacteria,3Y49D@57723|Acidobacteria,2JJ6K@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158380_k127_749104_1	204669.Acid345_4197	3.726e-47	182.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria,2JI3J@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_751481_1	1379698.RBG1_1C00001G0370	5.526e-122	412.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158380_k127_751481_0	621372.ACIH01000238_gene2054	6.132e-157	506.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,26RY1@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158380_k127_751481_3	717785.HYPMC_1579	3.466e-21	95.0	2EREK@1|root,33J04@2|Bacteria,1NKRV@1224|Proteobacteria,2UVAP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_751481_2	237368.SCABRO_03899	6.961e-83	282.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_752499_0	204669.Acid345_4193	9.465e-213	681.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria,2JKJ2@204432|Acidobacteriia	204432|Acidobacteriia	EU	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_752499_1	1121957.ATVL01000008_gene4368	4.676e-60	216.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158380_k127_752499_2	234267.Acid_3935	5.644e-05	45.0	COG1181@1|root,COG1181@2|Bacteria,3Y9AM@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
SRR25158380_k127_762453_4	1267533.KB906735_gene4834	0.0001621	46.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria,2JI53@204432|Acidobacteriia	204432|Acidobacteriia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158380_k127_762453_2	1210884.HG799462_gene8069	1.687e-56	206.0	COG0300@1|root,COG0300@2|Bacteria,2J0SJ@203682|Planctomycetes	203682|Planctomycetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_762453_0	335543.Sfum_0725	2.198e-73	256.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MRXH@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158380_k127_762453_1	234267.Acid_5735	3e-72	251.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_762453_3	234267.Acid_5734	4.623e-08	66.0	2CJPM@1|root,34C5K@2|Bacteria,3Y8HR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_763706_4	661478.OP10G_3471	3.572e-29	123.0	2CMS6@1|root,339SN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_763706_5	266265.Bxe_A0582	5.974e-05	51.0	2BGXF@1|root,32AXE@2|Bacteria,1PXHQ@1224|Proteobacteria,2WCXJ@28216|Betaproteobacteria,1K8P8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_763706_0	1469607.KK073769_gene5614	1.245e-164	529.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria,1HJSU@1161|Nostocales	1117|Cyanobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
SRR25158380_k127_763706_2	523791.Kkor_1666	2.02e-51	188.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,1RY74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_763706_3	313595.P700755_003981	7.442e-35	141.0	2E35R@1|root,32Y5N@2|Bacteria,4P5KG@976|Bacteroidetes,1IAK3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_763706_1	667632.KB890168_gene5207	3.779e-87	302.0	COG1680@1|root,COG1680@2|Bacteria,1MXHB@1224|Proteobacteria,2VXTZ@28216|Betaproteobacteria,1K34C@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_765590_4	1267535.KB906767_gene895	2.075e-39	148.0	2DB8U@1|root,2Z7SW@2|Bacteria,3Y3IM@57723|Acidobacteria	57723|Acidobacteria	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
SRR25158380_k127_765590_1	861299.J421_5607	2.655e-162	523.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
SRR25158380_k127_765590_0	234267.Acid_3941	1.854e-230	730.0	COG3345@1|root,COG3345@2|Bacteria,3Y3KH@57723|Acidobacteria	57723|Acidobacteria	G	Pkd domain containing protein	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase,PKD
SRR25158380_k127_765590_3	243090.RB5776	1.047e-70	251.0	COG0673@1|root,COG0673@2|Bacteria,2J216@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_765590_2	714943.Mucpa_5252	3.256e-144	463.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IPJT@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_767563_2	1089549.AZUQ01000001_gene242	1.466e-35	141.0	COG4899@1|root,COG4899@2|Bacteria,2IGN5@201174|Actinobacteria,4F00Y@85014|Glycomycetales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
SRR25158380_k127_767563_1	221288.JH992901_gene3877	1.177e-60	213.0	COG3871@1|root,COG3871@2|Bacteria,1GBSH@1117|Cyanobacteria,1JIRB@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
SRR25158380_k127_767563_0	469383.Cwoe_5411	2.195e-167	539.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_767937_3	1437448.AZRT01000027_gene1930	3.98e-41	162.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,1J1ES@118882|Brucellaceae	28211|Alphaproteobacteria	P	MgtE intracellular N domain	mgtE	GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158380_k127_767937_0	324602.Caur_2963	0.0	1160.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,376J5@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158380_k127_767937_4	638303.Thal_1281	7.162e-38	158.0	COG1232@1|root,COG1232@2|Bacteria,2G3UP@200783|Aquificae	200783|Aquificae	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158380_k127_767937_2	1121403.AUCV01000014_gene4563	1.199e-64	233.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158380_k127_767937_1	1124780.ANNU01000013_gene3855	1.636e-151	492.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,47K3T@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158380_k127_767937_5	404589.Anae109_4104	1.521e-12	71.0	COG1918@1|root,COG1918@2|Bacteria,1Q29B@1224|Proteobacteria,42VSV@68525|delta/epsilon subdivisions,2WS7A@28221|Deltaproteobacteria,2Z28N@29|Myxococcales	28221|Deltaproteobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SRR25158380_k127_774026_1	204669.Acid345_3525	4.491e-09	63.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria,2JHYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_774026_0	1443665.JACA01000007_gene99	3.565e-156	512.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,1HX0I@117743|Flavobacteriia,2YKMC@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
SRR25158380_k127_795592_1	216591.BCAM2275	2.757e-128	421.0	COG2856@1|root,COG2856@2|Bacteria,1PFUN@1224|Proteobacteria,2VS4F@28216|Betaproteobacteria,1KAF6@119060|Burkholderiaceae	28216|Betaproteobacteria	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,Peptidase_M78
SRR25158380_k127_795592_2	631362.Thi970DRAFT_02004	5.15e-50	183.0	COG1439@1|root,COG1439@2|Bacteria,1N0N0@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
SRR25158380_k127_795592_0	102129.Lepto7375DRAFT_0197	4.85e-176	561.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_795592_3	195250.CM001776_gene1528	9.785e-37	143.0	COG0845@1|root,COG0845@2|Bacteria,1G29R@1117|Cyanobacteria,1H05T@1129|Synechococcus	1117|Cyanobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158380_k127_797872_1	604331.AUHY01000021_gene1976	1.457e-35	141.0	2BAVZ@1|root,324BI@2|Bacteria,1WJT7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
SRR25158380_k127_797872_2	234267.Acid_4774	1.588e-30	128.0	2E32R@1|root,32Y2Y@2|Bacteria,3Y5RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_797872_0	234267.Acid_5396	3.618e-243	777.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_825005_0	1246459.KB898356_gene2162	7.649e-129	425.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,4B80H@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_825005_2	1069080.KB913028_gene1617	2.014e-81	280.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H1WW@909932|Negativicutes	909932|Negativicutes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158380_k127_825005_3	1120985.AUMI01000001_gene2096	1.6e-43	170.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4H2FC@909932|Negativicutes	909932|Negativicutes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158380_k127_825005_4	1121423.JONT01000001_gene1968	1.092e-41	162.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,260UN@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158380_k127_825005_10	459495.SPLC1_S100670	2.591e-05	50.0	COG3266@1|root,COG3266@2|Bacteria,1G5GU@1117|Cyanobacteria,1HBIT@1150|Oscillatoriales	1117|Cyanobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_825005_1	323259.Mhun_0648	4.661e-101	345.0	COG0614@1|root,COG1404@1|root,arCOG00702@2157|Archaea,arCOG03611@2157|Archaea,2XUT1@28890|Euryarchaeota,2NBHB@224756|Methanomicrobia	28890|Euryarchaeota	O	Subtilase family	hly	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8,TAT_signal
SRR25158380_k127_825005_9	1340493.JNIF01000003_gene4496	3.501e-16	93.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IP@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158380_k127_825005_8	330214.NIDE3048	3.639e-23	106.0	COG3216@1|root,COG3216@2|Bacteria,3J1DC@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
SRR25158380_k127_825005_6	278963.ATWD01000002_gene294	1.312e-34	135.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158380_k127_825005_5	1382359.JIAL01000001_gene2134	5.563e-36	139.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158380_k127_825005_7	1340493.JNIF01000003_gene4349	4.593e-28	118.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158380_k127_826363_0	682795.AciX8_3885	3.832e-94	322.0	COG0768@1|root,COG0768@2|Bacteria,3Y2XX@57723|Acidobacteria,2JHPS@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158380_k127_826363_13	204669.Acid345_3636	6.285e-05	51.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria,2JJBJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
SRR25158380_k127_826363_1	1121430.JMLG01000003_gene627	2.212e-82	284.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,260DT@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158380_k127_826363_6	1382359.JIAL01000001_gene1949	1.959e-44	166.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158380_k127_826363_2	671143.DAMO_0448	5.014e-61	219.0	COG0428@1|root,COG0428@2|Bacteria,2NQ6J@2323|unclassified Bacteria	2|Bacteria	P	ZIP Zinc transporter	zupT	-	-	ko:K07238,ko:K11021,ko:K16267	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5	-	-	Zip
SRR25158380_k127_826363_10	1031288.AXAA01000008_gene1253	1.928e-27	123.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,249DU@186801|Clostridia,36EEB@31979|Clostridiaceae	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158380_k127_826363_7	234267.Acid_0972	9.233e-36	146.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_826363_5	645991.Sgly_1590	1.096e-45	172.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,26236@186807|Peptococcaceae	186801|Clostridia	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158380_k127_826363_12	584708.Apau_0025	5.044e-09	61.0	COG4576@1|root,COG4576@2|Bacteria,3TBNZ@508458|Synergistetes	508458|Synergistetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SRR25158380_k127_826363_11	234267.Acid_0323	6.407e-25	107.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SRR25158380_k127_826363_9	234267.Acid_0322	1.403e-30	122.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SRR25158380_k127_826363_8	215803.DB30_1141	2.724e-34	133.0	COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,42UCN@68525|delta/epsilon subdivisions,2WQ3V@28221|Deltaproteobacteria,2Z195@29|Myxococcales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
SRR25158380_k127_826363_3	234267.Acid_0320	2.43e-59	214.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria	57723|Acidobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158380_k127_826363_4	671143.DAMO_2689	6.131e-53	195.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158380_k127_829152_1	1267535.KB906767_gene392	4.767e-95	320.0	COG3643@1|root,COG3643@2|Bacteria,3Y3HP@57723|Acidobacteria,2JIP9@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Formiminotransferase domain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_N
SRR25158380_k127_829152_2	349521.HCH_01090	1.747e-73	257.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XIB8@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158380_k127_829152_3	1297742.A176_05440	5.083e-33	130.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,42W18@68525|delta/epsilon subdivisions,2WZ19@28221|Deltaproteobacteria,2Z13S@29|Myxococcales	28221|Deltaproteobacteria	S	Transthyretin	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158380_k127_839329_6	234267.Acid_7345	1.518e-46	172.0	COG0500@1|root,COG2226@2|Bacteria,3Y44I@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158380_k127_839329_4	323261.Noc_2185	9.756e-87	297.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1WW7F@135613|Chromatiales	135613|Chromatiales	EP	PFAM Binding-protein-dependent transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158380_k127_839329_2	639030.JHVA01000001_gene3875	7.813e-97	323.0	COG1173@1|root,COG1173@2|Bacteria,3Y45P@57723|Acidobacteria,2JIKH@204432|Acidobacteriia	204432|Acidobacteriia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158380_k127_839329_1	204669.Acid345_2500	1.245e-104	347.0	COG0031@1|root,COG0031@2|Bacteria,3Y39Y@57723|Acidobacteria,2JJ08@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_839329_0	240015.ACP_1006	2.378e-154	496.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158380_k127_839329_5	861299.J421_2843	3.096e-63	228.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158380_k127_839329_7	243274.THEMA_00310	4.677e-21	99.0	COG1585@1|root,COG1585@2|Bacteria,2GDCD@200918|Thermotogae	200918|Thermotogae	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158380_k127_839329_3	215803.DB30_5516	6.997e-89	297.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria,2YX6B@29|Myxococcales	28221|Deltaproteobacteria	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158380_k127_842732_1	204669.Acid345_4348	4.949e-20	102.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
SRR25158380_k127_842732_2	937774.TEQUI_0749	5.967e-05	55.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,3T1NM@506|Alcaligenaceae	28216|Betaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158380_k127_842732_0	1191523.MROS_2208	5.898e-74	274.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	irp	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158380_k127_860491_3	593750.Metfor_0759	1.837e-19	100.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NB3I@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158380_k127_860491_1	682795.AciX8_3255	1.837e-63	243.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158380_k127_860491_2	1239962.C943_03877	3.085e-37	153.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158380_k127_860491_0	1267535.KB906767_gene1129	4.391e-157	530.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_863220_2	1111069.TCCBUS3UF1_17270	9.844e-86	310.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
SRR25158380_k127_863220_9	435908.IDSA_07235	0.0002535	46.0	COG1228@1|root,COG1228@2|Bacteria,1REFH@1224|Proteobacteria,1SM0E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_863220_1	1128421.JAGA01000003_gene3488	8.71e-86	293.0	COG3662@1|root,COG3662@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158380_k127_863220_0	997884.HMPREF1068_02686	2.775e-120	398.0	COG1520@1|root,COG4225@1|root,COG1520@2|Bacteria,COG4225@2|Bacteria,4NM00@976|Bacteroidetes,2FR1A@200643|Bacteroidia,4ANP9@815|Bacteroidaceae	976|Bacteroidetes	S	unsaturated rhamnogalacturonyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Glyco_hydro_88,PQQ_2
SRR25158380_k127_863220_5	706587.Desti_4853	2.634e-27	120.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria	1224|Proteobacteria	KT	ankyrin repeat	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158380_k127_863220_3	643867.Ftrac_3675	1.593e-56	203.0	29KMP@1|root,307IZ@2|Bacteria,4PQ15@976|Bacteroidetes,47YT5@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158380_k127_863220_4	1232437.KL662011_gene1449	4.709e-38	150.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MNCE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158380_k127_863220_6	861299.J421_0709	2.906e-12	70.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	LOR
SRR25158380_k127_863220_8	1396141.BATP01000005_gene6009	1.234e-06	53.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	LOR
SRR25158380_k127_868271_7	1216007.AOPM01000102_gene719	1.263e-08	64.0	COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,2Q0RQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	yjaG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09891	-	-	-	-	ko00000	-	-	-	DUF416
SRR25158380_k127_868271_1	1122218.KB893653_gene555	4.778e-103	349.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,1JR95@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM Aminotransferase class I and II	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_868271_3	204669.Acid345_0567	5.935e-59	208.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158380_k127_868271_0	1174528.JH992898_gene5069	0.0	1382.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1G0PS@1117|Cyanobacteria,1JJAE@1189|Stigonemataceae	1117|Cyanobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158380_k127_868271_4	1278073.MYSTI_03333	2.247e-45	177.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158380_k127_868271_2	502025.Hoch_2148	9.522e-63	227.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158380_k127_868271_5	697282.Mettu_3684	2.709e-44	163.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_868271_6	1121920.AUAU01000020_gene2543	2.061e-28	126.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000020_gene2543|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_871825_0	204669.Acid345_3340	7.191e-238	755.0	COG0550@1|root,COG0550@2|Bacteria,3Y343@57723|Acidobacteria,2JHPW@204432|Acidobacteriia	204432|Acidobacteriia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158380_k127_871825_2	401053.AciPR4_3125	1.099e-89	308.0	COG0758@1|root,COG0758@2|Bacteria,3Y42M@57723|Acidobacteria,2JI6N@204432|Acidobacteriia	204432|Acidobacteriia	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158380_k127_871825_1	1254432.SCE1572_07650	7.654e-215	679.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_879519_8	518766.Rmar_1042	4.402e-20	90.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1FIRE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158380_k127_879519_6	234267.Acid_5500	4.936e-35	143.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	HemolysinCabind,Pro_isomerase
SRR25158380_k127_879519_7	402777.KB235903_gene1611	5.558e-29	126.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158380_k127_879519_1	240015.ACP_2879	2.825e-78	267.0	COG0512@1|root,COG0512@2|Bacteria,3Y36D@57723|Acidobacteria,2JHQS@204432|Acidobacteriia	204432|Acidobacteriia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158380_k127_879519_0	1125863.JAFN01000001_gene2405	1.086e-87	302.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
SRR25158380_k127_879519_3	246194.CHY_1584	1.022e-59	216.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,42EQ2@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158380_k127_879519_4	309803.CTN_0550	6.63e-46	173.0	COG0135@1|root,COG0135@2|Bacteria,2GE4Q@200918|Thermotogae	200918|Thermotogae	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158380_k127_879519_5	1121918.ARWE01000001_gene1464	3.636e-36	151.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43AU6@68525|delta/epsilon subdivisions,2X68D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158380_k127_879519_2	234267.Acid_7888	1.09e-72	249.0	COG0133@1|root,COG0133@2|Bacteria,3Y45B@57723|Acidobacteria	57723|Acidobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_90420_0	472175.EL18_02361	4.896e-220	704.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,43IV8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158380_k127_90420_2	1232410.KI421413_gene522	6.036e-33	130.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,43SNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158380_k127_90420_1	321327.CYA_0862	1.064e-67	244.0	COG1252@1|root,COG1252@2|Bacteria,1G26A@1117|Cyanobacteria,1GZDB@1129|Synechococcus	1117|Cyanobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndbB	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_904378_3	1121104.AQXH01000001_gene1649	2.257e-29	122.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158380_k127_904378_0	316274.Haur_2944	4.546e-173	550.0	COG1830@1|root,COG1830@2|Bacteria,2G8VI@200795|Chloroflexi	200795|Chloroflexi	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158380_k127_904378_1	485913.Krac_11550	7.619e-89	298.0	COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi	200795|Chloroflexi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158380_k127_904378_4	1121413.JMKT01000010_gene864	3.741e-24	105.0	COG2119@1|root,COG2119@2|Bacteria,1PP1W@1224|Proteobacteria,42XF8@68525|delta/epsilon subdivisions,2WTC8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158380_k127_904378_2	378806.STAUR_1192	5.264e-49	183.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,43C3N@68525|delta/epsilon subdivisions,2X7EC@28221|Deltaproteobacteria,2YWP0@29|Myxococcales	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158380_k127_925188_2	868595.Desca_0708	1.591e-17	89.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,260H4@186807|Peptococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158380_k127_925188_0	401053.AciPR4_0872	1.144e-174	552.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158380_k127_925188_1	398767.Glov_1844	4.115e-41	171.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158380_k127_925188_3	1123502.AQXD01000005_gene1725	0.0009364	51.0	COG4254@1|root,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,1X3DI@135614|Xanthomonadales	135614|Xanthomonadales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SRR25158380_k127_925596_0	443143.GM18_0728	1.665e-291	900.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158380_k127_925596_2	99598.Cal7507_6086	2.457e-80	272.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158380_k127_925596_1	1267534.KB906758_gene2265	1.969e-220	691.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRR25158380_k127_933388_3	1082933.MEA186_06086	3.071e-71	261.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1R20U@1224|Proteobacteria,2U3F2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6
SRR25158380_k127_933388_0	497965.Cyan7822_1581	4.414e-163	522.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,3KGRJ@43988|Cyanothece	1117|Cyanobacteria	H	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_933388_2	1123242.JH636434_gene5626	7.684e-78	270.0	COG4886@1|root,COG5426@1|root,COG4886@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,Flg_new,LRR_5,LRR_6
SRR25158380_k127_933388_5	1198114.AciX9_2795	4.673e-10	71.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158380_k127_933388_4	204669.Acid345_0034	8.414e-21	95.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158380_k127_933388_1	880072.Desac_0720	1.247e-94	337.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_939438_1	247490.KSU1_D0503	2.167e-47	177.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_939438_2	298654.FraEuI1c_1850	2.433e-14	76.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4ESVF@85013|Frankiales	201174|Actinobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158380_k127_939438_3	1214101.BN159_5981	1.489e-09	63.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158380_k127_939438_0	706587.Desti_4096	1.414e-186	599.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MQWB@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158380_k127_940361_0	1267535.KB906767_gene1129	1.294e-76	267.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_940361_1	44056.XP_009040633.1	3.384e-27	123.0	2D0NW@1|root,2SEUV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_944703_1	1382359.JIAL01000001_gene2655	4.582e-84	290.0	COG3667@1|root,COG3667@2|Bacteria,3Y3FP@57723|Acidobacteria,2JITP@204432|Acidobacteriia	204432|Acidobacteriia	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_944703_0	1267535.KB906767_gene468	4.039e-256	819.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158380_k127_946369_0	1267535.KB906767_gene3834	1.339e-134	449.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_946369_1	204669.Acid345_0617	3.074e-34	134.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_950429_5	1183438.GKIL_3768	7.494e-05	46.0	COG0612@1|root,COG0612@2|Bacteria,1G303@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_950429_0	477974.Daud_0168	2.936e-246	773.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158380_k127_950429_3	204669.Acid345_1590	7.114e-55	211.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07708	ko02020,map02020	M00497,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,RsbRD_N
SRR25158380_k127_950429_1	243231.GSU2043	2.41e-62	225.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158380_k127_950429_2	247490.KSU1_D0287	5.325e-55	201.0	COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_950429_4	237368.SCABRO_00961	2.011e-08	66.0	COG1538@1|root,COG1538@2|Bacteria,2IZ8Q@203682|Planctomycetes	203682|Planctomycetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_961891_0	1123261.AXDW01000002_gene1666	7.288e-142	462.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1X5GT@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158380_k127_961891_1	880073.Calab_3078	9.331e-81	281.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_972030_0	639030.JHVA01000001_gene3370	2.143e-111	376.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158380_k127_972030_1	204669.Acid345_1040	1.32e-92	317.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_972096_5	880073.Calab_0823	2.313e-73	252.0	COG0572@1|root,COG0572@2|Bacteria,2NPKT@2323|unclassified Bacteria	2|Bacteria	F	Phosphoribulokinase / Uridine kinase family	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.19,2.7.1.48	ko:K00855,ko:K00876	ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200	M00165,M00166	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0893	PRK
SRR25158380_k127_972096_1	1430331.EP10_18360	4.817e-99	331.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158380_k127_972096_4	262724.TT_C1505	3.136e-85	292.0	COG1079@1|root,COG1079@2|Bacteria,1WJJD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158380_k127_972096_3	1408422.JHYF01000017_gene1857	1.242e-89	308.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,36EKF@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158380_k127_972096_0	670487.Ocepr_0826	1.236e-166	538.0	COG3845@1|root,COG3845@2|Bacteria,1WIKU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158380_k127_972096_6	221288.JH992901_gene3189	5.539e-28	114.0	2B1XW@1|root,31UE7@2|Bacteria,1G79D@1117|Cyanobacteria,1JMB6@1189|Stigonemataceae	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_972096_2	264462.Bd0445	3.646e-98	331.0	COG1744@1|root,COG1744@2|Bacteria,1NGHH@1224|Proteobacteria,42RBQ@68525|delta/epsilon subdivisions,2MTH8@213481|Bdellovibrionales,2WN1W@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	PFAM Basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158380_k127_978161_1	1267535.KB906767_gene5522	5.4e-78	284.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria,2JHJF@204432|Acidobacteriia	204432|Acidobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158380_k127_978161_0	204669.Acid345_1010	9.642e-87	299.0	COG0429@1|root,COG0429@2|Bacteria,3Y3MP@57723|Acidobacteria,2JI5X@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
SRR25158380_k127_978161_3	682795.AciX8_0692	1.159e-30	136.0	COG4775@1|root,COG4775@2|Bacteria,3Y7I1@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	POTRA
SRR25158380_k127_978161_2	234267.Acid_2537	3.906e-51	189.0	COG1595@1|root,COG1595@2|Bacteria,3Y5RY@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_979727_2	211165.AJLN01000116_gene2992	2.607e-26	117.0	COG0500@1|root,COG2226@2|Bacteria,1G96Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_979727_0	1267533.KB906736_gene1328	7.006e-98	344.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_979727_1	935567.JAES01000009_gene1715	2.705e-86	296.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,1X353@135614|Xanthomonadales	135614|Xanthomonadales	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
SRR25158380_k127_980052_3	397291.C804_02579	3.262e-16	81.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,27I7P@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158380_k127_980052_0	379066.GAU_3769	2.782e-93	321.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158380_k127_980052_1	1296415.JACC01000001_gene3610	2.519e-49	182.0	COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,1I2P2@117743|Flavobacteriia,2YIQT@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158380_k127_980052_2	321327.CYA_2298	7.075e-40	158.0	COG2197@1|root,COG2197@2|Bacteria,1GHXP@1117|Cyanobacteria,1GZT1@1129|Synechococcus	1117|Cyanobacteria	T	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_980052_4	497964.CfE428DRAFT_1144	1.519e-13	77.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,46TZW@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Reg_prop,Y_Y_Y
SRR25158380_k127_989751_0	886293.Sinac_1501	1.407e-224	717.0	COG3591@1|root,COG3591@2|Bacteria,2IXPD@203682|Planctomycetes	203682|Planctomycetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158380_k127_989751_1	1382359.JIAL01000001_gene1484	2.662e-216	696.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria,2JIDH@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158380_k127_989751_3	469383.Cwoe_3202	1.15e-43	165.0	COG1335@1|root,COG1335@2|Bacteria,2GPXN@201174|Actinobacteria,4CQB9@84995|Rubrobacteria	84995|Rubrobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158380_k127_989751_2	1173024.KI912148_gene2699	1.31e-54	198.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
## 3643 queries scanned
## Total time (seconds): 7.372956275939941
## Rate: 494.10 q/s