## Sun Dec 14 23:12:55 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158380_bin.3.fa -m mmseqs --itype genome -o SRR25158380_bin.3 --output_dir /data/result/bins/wyx/egg/SRR25158380_bin.3 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158380_k127_1016904_1	861299.J421_3111	2.71e-111	378.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158380_k127_1016904_0	471223.GWCH70_3348	9.775e-154	508.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1WESD@129337|Geobacillus	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158380_k127_1016904_2	861299.J421_3109	5.643e-21	96.0	COG2331@1|root,COG2331@2|Bacteria,1ZU2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1023529_0	314285.KT71_18591	9.383e-137	457.0	COG0769@1|root,COG0769@2|Bacteria,1R52S@1224|Proteobacteria,1RVEK@1236|Gammaproteobacteria,1J96F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Mur ligase family, glutamate ligase domain	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_1023529_1	1232410.KI421413_gene573	4.354e-45	168.0	COG4276@1|root,COG4276@2|Bacteria,1N6EC@1224|Proteobacteria,42U3N@68525|delta/epsilon subdivisions,2WQTN@28221|Deltaproteobacteria,43VBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158380_k127_1024532_2	1379270.AUXF01000002_gene1186	1.707e-97	341.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158380_k127_1024532_1	1379270.AUXF01000002_gene1185	4.52e-105	357.0	COG0486@1|root,COG0486@2|Bacteria,1ZSRA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158380_k127_1024532_0	1379270.AUXF01000002_gene1184	2.689e-113	375.0	COG5504@1|root,COG5504@2|Bacteria,1ZTCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1024532_3	1287488.HMPREF0671_01400	2.838e-10	66.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, S54 family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
SRR25158380_k127_1024741_0	861299.J421_0254	1.844e-306	947.0	COG0405@1|root,COG0405@2|Bacteria,1ZUIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158380_k127_1024741_1	861299.J421_1684	2.048e-45	189.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_1027515_2	379066.GAU_3774	4.254e-39	151.0	COG3019@1|root,COG3019@2|Bacteria,1ZTWW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
SRR25158380_k127_1027515_1	861299.J421_3775	1.088e-141	467.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158380_k127_1027515_0	1379270.AUXF01000003_gene3680	6.638e-206	648.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158380_k127_1036038_1	1300345.LF41_2250	9.916e-115	381.0	COG0823@1|root,COG0823@2|Bacteria,1R1F4@1224|Proteobacteria,1T0CM@1236|Gammaproteobacteria,1X5C1@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158380_k127_1036038_0	1144275.COCOR_03147	4.331e-154	501.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_1036038_2	861299.J421_4524	8.529e-111	369.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158380_k127_1036038_3	862751.SACTE_5491	4.98e-105	352.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_1036038_4	37919.EP51_36085	3.352e-94	325.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4FVIH@85025|Nocardiaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158380_k127_1036038_5	926550.CLDAP_26080	1.007e-63	226.0	COG1879@1|root,COG1879@2|Bacteria,2G97E@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
SRR25158380_k127_1045306_4	1124780.ANNU01000089_gene313	2.596e-45	171.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158380_k127_1045306_0	379066.GAU_0935	1.015e-105	351.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_1045306_1	861299.J421_2839	1.599e-89	320.0	COG2377@1|root,COG2377@2|Bacteria,1ZSZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SRR25158380_k127_1045306_2	1379270.AUXF01000004_gene2957	1.208e-85	310.0	COG1472@1|root,COG1472@2|Bacteria,1ZST8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3
SRR25158380_k127_1045306_3	706587.Desti_1505	8.27e-78	275.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR25158380_k127_1049003_0	861299.J421_6125	1.191e-263	845.0	COG0841@1|root,COG0841@2|Bacteria,1ZT98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MMPL family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_1049003_1	290397.Adeh_2021	1.077e-62	224.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,2YZVB@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_1051383_5	379066.GAU_1682	1.087e-32	130.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158380_k127_1051383_3	861299.J421_3314	4.519e-56	209.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158380_k127_1051383_4	861299.J421_3315	6.532e-50	188.0	COG1211@1|root,COG1211@2|Bacteria,1ZSTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158380_k127_1051383_0	861299.J421_3316	1.227e-166	556.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
SRR25158380_k127_1051383_1	1379270.AUXF01000006_gene205	1.102e-162	524.0	COG0305@1|root,COG0305@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158380_k127_1051383_2	379066.GAU_1687	2.356e-67	234.0	COG1573@1|root,COG1573@2|Bacteria,1ZTG5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158380_k127_1065654_0	1380391.JIAS01000017_gene543	6.282e-107	354.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_1065654_1	234267.Acid_1190	6.028e-32	133.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158380_k127_1065654_2	156578.ATW7_11911	9.995e-05	51.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
SRR25158380_k127_1091025_1	1379270.AUXF01000004_gene3345	2.333e-14	76.0	COG0762@1|root,COG0762@2|Bacteria,1ZTUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158380_k127_1091025_0	861299.J421_1125	2.971e-132	426.0	COG0208@1|root,COG0208@2|Bacteria,1ZTAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Fatty acid desaturase	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
SRR25158380_k127_1091940_1	861299.J421_5666	5.698e-60	211.0	COG3652@1|root,COG3652@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4142)	MA20_42090	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRR25158380_k127_1091940_2	330214.NIDE3649	6.377e-48	181.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_1091940_0	1121920.AUAU01000009_gene1955	9.408e-168	536.0	COG1858@1|root,COG1858@2|Bacteria,3Y7B8@57723|Acidobacteria	57723|Acidobacteria	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1092094_0	1379270.AUXF01000005_gene464	1.842e-223	701.0	COG4147@1|root,COG4147@2|Bacteria,1ZUA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158380_k127_1092094_1	1379270.AUXF01000002_gene1132	7.174e-77	263.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR25158380_k127_1112568_1	861299.J421_1072	1.226e-172	548.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
SRR25158380_k127_1112568_0	379066.GAU_0001	3.738e-179	572.0	COG0593@1|root,COG0593@2|Bacteria,1ZSQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158380_k127_1112568_2	1379270.AUXF01000002_gene1189	4.059e-18	85.0	COG0230@1|root,COG0230@2|Bacteria,1ZU59@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158380_k127_1127990_1	526227.Mesil_1097	1.339e-52	196.0	COG2819@1|root,COG2819@2|Bacteria,1WMFX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158380_k127_1127990_0	1237500.ANBA01000011_gene3370	4.969e-58	218.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158380_k127_114630_2	1128421.JAGA01000003_gene2959	1.241e-51	186.0	COG0221@1|root,COG0221@2|Bacteria,2NPVX@2323|unclassified Bacteria	2|Bacteria	C	Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158380_k127_114630_0	937777.Deipe_2633	1.434e-126	413.0	COG4864@1|root,COG4864@2|Bacteria,1WI32@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
SRR25158380_k127_114630_1	937777.Deipe_2634	2.284e-88	307.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR25158380_k127_114630_5	1379270.AUXF01000006_gene198	2.645e-10	68.0	297VI@1|root,2ZV24@2|Bacteria,1ZU61@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_114630_4	861299.J421_3331	6.783e-35	140.0	COG1595@1|root,COG1595@2|Bacteria,1ZTKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_114630_3	1379270.AUXF01000006_gene195	9.217e-48	187.0	COG0584@1|root,COG0584@2|Bacteria,1ZTTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158380_k127_1148993_5	795666.MW7_0877	7.673e-18	97.0	COG2037@1|root,COG2037@2|Bacteria,1MVSD@1224|Proteobacteria,2VJSP@28216|Betaproteobacteria,1K1QD@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	-	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
SRR25158380_k127_1148993_0	1380390.JIAT01000010_gene4326	1.931e-187	602.0	COG1229@1|root,COG1229@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase subunit A	fhcA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_1148993_3	886293.Sinac_1241	3.469e-62	232.0	COG1029@1|root,COG1029@2|Bacteria,2IYZN@203682|Planctomycetes	203682|Planctomycetes	C	formylmethanofuran dehydrogenase, subunit	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158380_k127_1148993_2	1380390.JIAT01000010_gene4328	7.283e-82	285.0	COG2218@1|root,COG2218@2|Bacteria	2|Bacteria	C	formylmethanofuran dehydrogenase activity	fhcC	GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
SRR25158380_k127_1148993_1	1380390.JIAT01000010_gene4327	2.989e-112	372.0	COG2037@1|root,COG2037@2|Bacteria	2|Bacteria	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
SRR25158380_k127_1148993_4	1380390.JIAT01000010_gene4326	2.353e-34	135.0	COG1229@1|root,COG1229@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase subunit A	fhcA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_1164820_1	861299.J421_2432	1.177e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_1164820_2	1210884.HG799462_gene7858	3.104e-20	95.0	COG2149@1|root,COG2149@2|Bacteria,2J0RV@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158380_k127_1164820_0	1123487.KB892835_gene3590	2.603e-42	163.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,2VX1P@28216|Betaproteobacteria,2KZ3V@206389|Rhodocyclales	206389|Rhodocyclales	S	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
SRR25158380_k127_1170215_0	379066.GAU_2518	4.031e-136	442.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158380_k127_1170215_1	1379270.AUXF01000003_gene3395	2.125e-35	145.0	COG3166@1|root,COG3166@2|Bacteria,1ZTR8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
SRR25158380_k127_1170215_2	1379270.AUXF01000003_gene3396	0.0003898	47.0	COG3167@1|root,COG3167@2|Bacteria,1ZTZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR25158380_k127_118791_2	1248916.ANFY01000010_gene419	2.104e-06	50.0	COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria,2UCCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
SRR25158380_k127_118791_1	1121920.AUAU01000030_gene2713	3.213e-18	89.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_118791_0	1237149.C900_02066	2.817e-133	437.0	COG0076@1|root,COG0076@2|Bacteria,4NGZB@976|Bacteroidetes	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158380_k127_1190824_2	1379270.AUXF01000002_gene1166	2.212e-49	187.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158380_k127_1190824_0	861299.J421_1864	3.963e-186	600.0	COG0038@1|root,COG0038@2|Bacteria	2|Bacteria	P	chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158380_k127_1190824_1	861299.J421_0908	2.037e-63	222.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158380_k127_1190824_3	861299.J421_0929	2.884e-06	50.0	COG1434@1|root,COG1434@2|Bacteria,1ZTZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158380_k127_1220609_2	867903.ThesuDRAFT_00783	5.654e-35	138.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158380_k127_1220609_3	861299.J421_3304	5.094e-17	83.0	COG1977@1|root,COG1977@2|Bacteria,1ZU69@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158380_k127_1220609_1	1379270.AUXF01000006_gene217	2.283e-45	167.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158380_k127_1220609_0	264732.Moth_0881	3.561e-107	356.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,42FFM@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158380_k127_1226826_0	886293.Sinac_3964	1.246e-143	470.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158380_k127_1255324_2	1411123.JQNH01000001_gene3254	1.249e-44	169.0	COG3685@1|root,COG3685@2|Bacteria,1REKN@1224|Proteobacteria,2U73U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158380_k127_1255324_1	379066.GAU_0275	5.354e-57	214.0	COG0025@1|root,COG0025@2|Bacteria,1ZTCR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1255324_0	861299.J421_1859	1.222e-78	292.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158380_k127_1264753_1	1379270.AUXF01000002_gene1577	1.836e-133	454.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_1264753_0	861299.J421_1230	2.745e-212	699.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1230|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_1264753_2	1037409.BJ6T_23810	5.088e-42	154.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158380_k127_1265076_0	1382356.JQMP01000004_gene524	6.225e-99	328.0	COG2225@1|root,COG2225@2|Bacteria,2G63R@200795|Chloroflexi,27Y0V@189775|Thermomicrobia	189775|Thermomicrobia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158380_k127_1265076_1	1144305.PMI02_01335	7.783e-15	83.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,2KAUZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRR25158380_k127_1282837_2	1121930.AQXG01000001_gene1300	1.324e-12	77.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1IYME@117747|Sphingobacteriia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158380_k127_1282837_1	1121930.AQXG01000001_gene1299	1.961e-69	268.0	COG3391@1|root,COG3391@2|Bacteria,4PJH2@976|Bacteroidetes,1IZRD@117747|Sphingobacteriia	976|Bacteroidetes	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158380_k127_1282837_0	1089550.ATTH01000001_gene1477	1.369e-198	651.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
SRR25158380_k127_1285742_6	641491.DND132_1038	1.689e-62	229.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,42MZ8@68525|delta/epsilon subdivisions,2WMM3@28221|Deltaproteobacteria,2MG24@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_1285742_4	1499967.BAYZ01000026_gene1563	7.294e-93	318.0	COG0687@1|root,COG0687@2|Bacteria,2NPSD@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158380_k127_1285742_3	1120950.KB892800_gene1634	1.891e-93	321.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,4DPNP@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158380_k127_1285742_5	1121090.KB894694_gene2132	6.618e-74	256.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,1ZCWA@1386|Bacillus	91061|Bacilli	E	COG1177 ABC-type spermidine putrescine transport system, permease component II	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158380_k127_1285742_2	479434.Sthe_1277	1.082e-93	315.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi,27XNS@189775|Thermomicrobia	189775|Thermomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158380_k127_1285742_1	1382356.JQMP01000003_gene1906	7.861e-104	349.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,27XG2@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158380_k127_1285742_0	204669.Acid345_1534	9.416e-149	485.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	57723|Acidobacteria	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_1302100_1	861299.J421_4355	3.902e-08	57.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1302100_0	861299.J421_1230	8.643e-129	447.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1230|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_1302100_2	1379698.RBG1_1C00001G1235	1.211e-07	64.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
SRR25158380_k127_1320679_1	861299.J421_2940	3.776e-22	104.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
SRR25158380_k127_1320679_0	1379270.AUXF01000005_gene461	9.747e-161	551.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158380_k127_1332135_0	861299.J421_2656	3.033e-239	753.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158380_k127_1356387_4	1267535.KB906767_gene2392	3.432e-44	164.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRR25158380_k127_1356387_3	426355.Mrad2831_0802	5.378e-82	285.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,1JSI3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158380_k127_1356387_0	861299.J421_3883	0.0	1349.0	COG1429@1|root,COG1429@2|Bacteria	2|Bacteria	H	ligase activity, forming nitrogen-metal bonds	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,Glyco_hydro_63
SRR25158380_k127_1356387_1	1496688.ER33_11555	1.82e-250	796.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158380_k127_1356387_2	861299.J421_1879	1.539e-166	536.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_1356867_0	234267.Acid_0372	1.368e-158	514.0	COG3104@1|root,COG3104@2|Bacteria,3Y6W5@57723|Acidobacteria	57723|Acidobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158380_k127_1356867_1	298653.Franean1_2295	3.186e-35	141.0	COG1670@1|root,COG1670@2|Bacteria,2GT64@201174|Actinobacteria,4EWNI@85013|Frankiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158380_k127_1359422_4	1124780.ANNU01000019_gene1696	1.313e-15	83.0	2DS15@1|root,33E22@2|Bacteria,4NYSK@976|Bacteroidetes,47WV4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1359422_2	1379698.RBG1_1C00001G1893	2.621e-31	140.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158380_k127_1359422_3	404380.Gbem_1783	5.778e-31	143.0	COG5653@1|root,COG5653@2|Bacteria,1NCB6@1224|Proteobacteria,430DK@68525|delta/epsilon subdivisions,2WVKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158380_k127_1359422_1	269799.Gmet_2016	3.239e-56	212.0	COG0399@1|root,COG0399@2|Bacteria,1REP8@1224|Proteobacteria,42S4Y@68525|delta/epsilon subdivisions,2WNVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158380_k127_1359422_0	861299.J421_1605	5.687e-69	238.0	COG4119@1|root,COG4119@2|Bacteria	2|Bacteria	L	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158380_k127_1370314_3	861299.J421_3832	5.532e-31	125.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158380_k127_1370314_2	861299.J421_3833	1.38e-50	199.0	COG0566@1|root,COG0566@2|Bacteria,1ZTVA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNA 2'-O ribose methyltransferase substrate binding	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158380_k127_1370314_1	1449080.JQMV01000003_gene1071	5.675e-69	257.0	COG0351@1|root,COG0351@2|Bacteria,1WIN0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158380_k127_1370314_0	379066.GAU_2354	2.595e-86	297.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158380_k127_1370314_4	1304284.L21TH_2085	8.567e-23	99.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
SRR25158380_k127_1382358_0	1379270.AUXF01000002_gene1773	2.088e-151	487.0	COG1271@1|root,COG1271@2|Bacteria,1ZUHF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158380_k127_1382358_1	357808.RoseRS_3549	1.711e-65	237.0	COG1407@1|root,COG1407@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	MA20_22045	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158380_k127_1382358_2	357808.RoseRS_3430	1.025e-47	174.0	COG1201@1|root,COG1201@2|Bacteria	2|Bacteria	L	RNA secondary structure unwinding	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158380_k127_1387435_2	379066.GAU_1581	4.032e-34	145.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158380_k127_1387435_1	861299.J421_3213	7.634e-109	382.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158380_k127_1387435_0	518766.Rmar_0302	4.822e-140	454.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1FISX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_1394006_3	1502850.FG91_03044	1.503e-56	205.0	COG3306@1|root,COG3306@2|Bacteria,1N6W4@1224|Proteobacteria	1224|Proteobacteria	M	glycosyltransferase involved in LPS biosynthesis	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
SRR25158380_k127_1394006_4	479434.Sthe_0904	9.217e-48	187.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1394006_0	1449350.OCH239_17360	4.987e-92	313.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158380_k127_1394006_2	1385935.N836_10115	1.387e-56	211.0	COG0500@1|root,COG2226@2|Bacteria,1G3CH@1117|Cyanobacteria,1HAB6@1150|Oscillatoriales	1117|Cyanobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_1394006_1	1089550.ATTH01000001_gene2493	6.936e-84	291.0	COG0438@1|root,COG0438@2|Bacteria,4NKBB@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158380_k127_1428373_1	861299.J421_3968	1.978e-146	502.0	COG1206@1|root,COG1206@2|Bacteria,1ZTB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	gid	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158380_k127_1428373_0	324602.Caur_3917	7.871e-217	698.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,3753B@32061|Chloroflexia	32061|Chloroflexia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158380_k127_1428373_4	379066.GAU_2511	1.371e-30	134.0	COG0703@1|root,COG0703@2|Bacteria,1ZTXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158380_k127_1428373_3	649747.HMPREF0083_03642	1.708e-116	389.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,26QTH@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158380_k127_1428373_2	861299.J421_3976	1.63e-122	406.0	COG4796@1|root,COG4796@2|Bacteria,1ZSRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	AMIN domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
SRR25158380_k127_1445716_0	880073.Calab_2972	3.939e-77	273.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158380_k127_1445716_3	379066.GAU_0150	1.23e-18	94.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SRR25158380_k127_1445716_1	1054213.HMPREF9946_01739	4.492e-54	201.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158380_k127_1445716_2	882086.SacxiDRAFT_2992	4.547e-48	188.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DXPV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_1447264_0	861299.J421_1151	3.795e-199	634.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158380_k127_1447264_1	1267534.KB906759_gene1822	6.974e-56	206.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	mmpL3	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264	-	ko:K06994,ko:K07003,ko:K20466,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.5,2.A.6.5.6	-	-	MMPL
SRR25158380_k127_1447566_0	379066.GAU_1750	2.437e-188	593.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1ZSMF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158380_k127_1447566_1	518766.Rmar_2301	3.315e-12	79.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_2301|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1449645_5	1434325.AZQN01000003_gene2773	2.36e-40	152.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,47KS1@768503|Cytophagia	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
SRR25158380_k127_1449645_1	760117.JN27_01960	4.703e-186	602.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,2VHF6@28216|Betaproteobacteria,476RX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Alpha amylase, catalytic domain	malS	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR25158380_k127_1449645_0	1048983.EL17_01845	1.329e-201	647.0	COG0366@1|root,COG0366@2|Bacteria,4PIQV@976|Bacteroidetes,47TNQ@768503|Cytophagia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158380_k127_1449645_8	861299.J421_3196	1.208e-09	68.0	2FIMZ@1|root,34ADU@2|Bacteria,1ZTYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1449645_3	861299.J421_3197	1.715e-86	309.0	COG0796@1|root,COG0796@2|Bacteria,1ZUQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158380_k127_1449645_6	861299.J421_3198	1.85e-37	151.0	COG2908@1|root,COG2908@2|Bacteria,1ZTNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
SRR25158380_k127_1449645_7	861299.J421_3199	6.463e-29	131.0	COG0824@1|root,COG0824@2|Bacteria,1ZTY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158380_k127_1449645_4	1379270.AUXF01000005_gene834	3.627e-51	205.0	COG0652@1|root,COG0652@2|Bacteria,1ZUUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158380_k127_1449645_2	1379698.RBG1_1C00001G1445	8.965e-148	502.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
SRR25158380_k127_1449645_9	379066.GAU_1568	2.59e-05	53.0	2F5A9@1|root,33XWF@2|Bacteria,1ZTU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1449968_0	379066.GAU_1145	2.815e-116	387.0	COG0577@1|root,COG0577@2|Bacteria,1ZUU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1449968_2	861299.J421_2902	5.569e-92	329.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_1449968_1	861299.J421_2903	1.151e-111	374.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158380_k127_1449968_3	861299.J421_2904	2.978e-14	73.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158380_k127_1462594_0	861299.J421_3810	3.225e-127	426.0	COG3280@1|root,COG3280@2|Bacteria	2|Bacteria	G	synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
SRR25158380_k127_1462594_1	861299.J421_0997	5.488e-85	296.0	COG2326@1|root,COG2326@2|Bacteria,1ZT29@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158380_k127_1468012_4	653045.Strvi_1389	0.0001641	52.0	COG4221@1|root,COG4221@2|Bacteria,2GKJ8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_1468012_0	861299.J421_2704	8.716e-82	277.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158380_k127_1468012_2	518766.Rmar_0192	2.552e-52	189.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158380_k127_1468012_1	379066.GAU_0585	2.313e-78	271.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158380_k127_1477739_1	1379270.AUXF01000004_gene3101	1.634e-32	140.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158380_k127_1477739_0	861299.J421_2696	2.639e-113	377.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
SRR25158380_k127_1510583_2	1278073.MYSTI_01766	3.572e-92	317.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_1510583_1	1267535.KB906767_gene632	6.999e-115	374.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_1510583_0	861299.J421_0290	2.91e-140	460.0	COG0845@1|root,COG0845@2|Bacteria,1ZUP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
SRR25158380_k127_1517233_1	1198114.AciX9_0973	8.766e-108	367.0	COG1543@1|root,COG1543@2|Bacteria,3Y3C3@57723|Acidobacteria,2JIW9@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158380_k127_1517233_0	379066.GAU_1365	4.076e-185	590.0	COG0297@1|root,COG0297@2|Bacteria,1ZUKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158380_k127_1530366_1	1297742.A176_04817	3.9e-96	318.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,42Z2R@68525|delta/epsilon subdivisions,2WUGF@28221|Deltaproteobacteria,2Z37Y@29|Myxococcales	28221|Deltaproteobacteria	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Mac
SRR25158380_k127_1530366_0	365046.Rta_06020	9.561e-139	447.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria,4AGW7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1530366_3	96561.Dole_3268	1.427e-18	96.0	COG0784@1|root,COG2202@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
SRR25158380_k127_1530366_4	1304877.KI519399_gene3280	0.0003865	49.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQS8@28211|Alphaproteobacteria,3JXE1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
SRR25158380_k127_1530366_2	1379698.RBG1_1C00001G0798	7.28e-59	224.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
SRR25158380_k127_1543585_0	479434.Sthe_2317	1.161e-138	456.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,27YVX@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR25158380_k127_1543585_1	997346.HMPREF9374_1821	2.139e-11	72.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,4IRFV@91061|Bacilli,27BU9@186824|Thermoactinomycetaceae	91061|Bacilli	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158380_k127_1547645_1	861299.J421_3930	1.676e-91	305.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158380_k127_1547645_0	378806.STAUR_2333	4.894e-181	576.0	COG0436@1|root,COG0436@2|Bacteria,1QHKS@1224|Proteobacteria,42Z0T@68525|delta/epsilon subdivisions,2WU4I@28221|Deltaproteobacteria,2YTVA@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158380_k127_1547645_3	1095769.CAHF01000022_gene214	1.661e-23	106.0	COG2020@1|root,COG2020@2|Bacteria,1PK67@1224|Proteobacteria,2WATQ@28216|Betaproteobacteria,4787Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1547645_2	1379698.RBG1_1C00001G0629	6.844e-57	206.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
SRR25158380_k127_1557771_2	710111.FraQA3DRAFT_0344	4.179e-82	290.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4EREP@85013|Frankiales	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158380_k127_1557771_0	867903.ThesuDRAFT_00760	8.537e-89	304.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158380_k127_1557771_1	861299.J421_2732	2.937e-83	300.0	COG1024@1|root,COG1024@2|Bacteria,1ZT76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158380_k127_1557771_3	861299.J421_2731	3.39e-15	85.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158380_k127_1559093_2	861299.J421_2883	6.297e-41	153.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158380_k127_1559093_3	861299.J421_2882	3.227e-18	89.0	COG0718@1|root,COG0718@2|Bacteria,1ZU1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158380_k127_1559093_0	861299.J421_2881	4.367e-156	518.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158380_k127_1559093_4	1109445.AGSX01000186_gene2370	3.622e-07	63.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1Z0Y5@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	membrane	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158380_k127_1559093_1	379066.GAU_1107	1.212e-68	238.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158380_k127_1561606_6	1411123.JQNH01000001_gene3173	2.22e-23	105.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2U62M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158380_k127_1561606_1	861299.J421_3788	2.579e-59	216.0	COG5637@1|root,COG5637@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
SRR25158380_k127_1561606_0	215803.DB30_4799	9.507e-104	347.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,43AHS@68525|delta/epsilon subdivisions,2WTYK@28221|Deltaproteobacteria,2YYVT@29|Myxococcales	28221|Deltaproteobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_1561606_3	1095769.CAHF01000010_gene1115	2.514e-48	185.0	COG5637@1|root,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,2WGS9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,Polyketide_cyc
SRR25158380_k127_1561606_4	316274.Haur_3774	1.074e-28	119.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158380_k127_1561606_2	247490.KSU1_C1131	2.643e-53	192.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
SRR25158380_k127_1561606_5	404589.Anae109_4070	2.566e-25	109.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria	1224|Proteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	iEcolC_1368.EcolC_1983	Sod_Cu
SRR25158380_k127_1571659_2	379066.GAU_1401	2.839e-41	158.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158380_k127_1571659_1	861299.J421_3049	2.047e-50	205.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158380_k127_1571659_0	1379270.AUXF01000005_gene661	1.166e-242	773.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_1603369_1	1089550.ATTH01000001_gene1912	6.686e-32	133.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1FJ98@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25
SRR25158380_k127_1603369_0	861299.J421_2936	8.65e-132	428.0	COG0216@1|root,COG0216@2|Bacteria,1ZSNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158380_k127_1603369_2	177437.HRM2_17070	3.887e-23	100.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,2MM5X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158380_k127_1603369_3	314285.KT71_18122	5.444e-10	63.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1J7R3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
SRR25158380_k127_160864_0	1123368.AUIS01000044_gene15	1.424e-190	602.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158380_k127_160864_5	379066.GAU_2648	5.604e-27	124.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158380_k127_160864_1	251229.Chro_2915	2.922e-77	269.0	COG2267@1|root,COG2267@2|Bacteria,1G2EN@1117|Cyanobacteria,3VIY7@52604|Pleurocapsales	1117|Cyanobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158380_k127_160864_4	861299.J421_2069	3.252e-41	154.0	COG0234@1|root,COG0234@2|Bacteria,1ZU6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
SRR25158380_k127_160864_3	861299.J421_0057	1.371e-46	175.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158380_k127_160864_2	861299.J421_1157	7.21e-72	252.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158380_k127_160864_6	234267.Acid_6499	2.721e-11	71.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria	57723|Acidobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158380_k127_1616777_1	861299.J421_2940	1.659e-122	409.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
SRR25158380_k127_1616777_2	748280.NH8B_3246	2.253e-31	135.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,2VS2J@28216|Betaproteobacteria,2KR6Q@206351|Neisseriales	206351|Neisseriales	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158380_k127_1616777_0	861299.J421_2940	1.153e-122	408.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
SRR25158380_k127_1622653_2	562970.Btus_1769	6.743e-100	349.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158380_k127_1622653_1	1379270.AUXF01000006_gene287	1.718e-138	452.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
SRR25158380_k127_1622653_0	1379270.AUXF01000001_gene1904	7.88e-155	508.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158380_k127_1624149_3	883126.HMPREF9710_02937	5.184e-88	304.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2WAKQ@28216|Betaproteobacteria,477CY@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158380_k127_1624149_4	861299.J421_6270	1.244e-15	80.0	2DJDE@1|root,305RC@2|Bacteria,1ZV7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1624149_1	1340493.JNIF01000004_gene829	5.754e-257	803.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158380_k127_1624149_0	1379270.AUXF01000003_gene3768	1.607e-287	897.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
SRR25158380_k127_1624149_2	1121930.AQXG01000001_gene1531	3.764e-110	361.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
SRR25158380_k127_1642031_0	1379698.RBG1_1C00001G0436	4.482e-54	208.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_1642031_1	365046.Rta_10950	7.026e-34	136.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,4AAIX@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158380_k127_1658162_3	1121926.AXWO01000035_gene4027	4.777e-09	57.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EXWB@85014|Glycomycetales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158380_k127_1658162_2	379066.GAU_2370	3.663e-69	241.0	COG0704@1|root,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158380_k127_1658162_0	861299.J421_3843	4.425e-132	441.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1ZTH0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FPT	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158380_k127_1658162_1	404589.Anae109_1579	2.91e-86	292.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158380_k127_1659013_0	861299.J421_6125	1.399e-106	353.0	COG0841@1|root,COG0841@2|Bacteria,1ZT98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MMPL family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_1659013_2	1144275.COCOR_01812	2.788e-46	191.0	COG1680@1|root,COG1680@2|Bacteria,1RGG3@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_1659013_3	1267533.KB906733_gene3590	4.234e-40	171.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,GSDH,SGL
SRR25158380_k127_1659013_1	234267.Acid_0099	2.376e-82	286.0	2EBMM@1|root,335MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1659013_6	1296415.JACC01000022_gene4083	8.654e-09	67.0	28JKT@1|root,2Z9DG@2|Bacteria,4NJJK@976|Bacteroidetes,1HYPI@117743|Flavobacteriia,2YI0V@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRR25158380_k127_1659013_4	1267535.KB906767_gene891	1.16e-39	152.0	COG2318@1|root,COG2318@2|Bacteria,3Y5DP@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_1677024_0	1144275.COCOR_00464	0.0	1437.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158380_k127_1677024_1	215803.DB30_4552	4.703e-88	316.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42RBE@68525|delta/epsilon subdivisions,2WN7J@28221|Deltaproteobacteria,2YZ5D@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_1677024_2	379066.GAU_3092	2.766e-64	231.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_1702515_0	1379270.AUXF01000004_gene3229	3.04e-56	221.0	COG5000@1|root,COG5000@2|Bacteria,1ZTBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_1702515_3	379066.GAU_0548	1.493e-18	99.0	COG4767@1|root,COG4767@2|Bacteria,1ZU1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158380_k127_1702515_4	512565.AMIS_45030	9.977e-14	82.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_1702515_1	452662.SJA_C2-02120	5.116e-42	171.0	COG2244@1|root,COG2244@2|Bacteria,1NX2R@1224|Proteobacteria,2USND@28211|Alphaproteobacteria,2KAHK@204457|Sphingomonadales	204457|Sphingomonadales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1702515_2	1122180.Lokhon_00095	3.246e-26	110.0	COG0438@1|root,COG0438@2|Bacteria,1RBYC@1224|Proteobacteria,2U6QI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1721309_0	1379698.RBG1_1C00001G1725	9.532e-319	1007.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
SRR25158380_k127_1721309_1	215803.DB30_3564	1.415e-23	115.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158380_k127_1738120_1	309801.trd_A0395	8.843e-104	356.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158380_k127_1738120_0	391625.PPSIR1_22374	2.401e-123	411.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42MGQ@68525|delta/epsilon subdivisions,2WSUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_1738120_2	869210.Marky_2090	5.367e-52	195.0	COG0157@1|root,COG0157@2|Bacteria,1WIHZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158380_k127_1738120_3	1120972.AUMH01000013_gene2404	1.167e-21	95.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,279AN@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158380_k127_1778909_2	861299.J421_3393	1.667e-116	380.0	COG0777@1|root,COG0777@2|Bacteria,1ZSSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158380_k127_1778909_4	379066.GAU_1755	1.14e-84	297.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
SRR25158380_k127_1778909_1	861299.J421_3391	6.664e-136	446.0	COG0124@1|root,COG0124@2|Bacteria,1ZSXX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
SRR25158380_k127_1778909_0	861299.J421_3390	6.269e-222	698.0	COG0442@1|root,COG0442@2|Bacteria,1ZT48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158380_k127_1778909_3	573370.DMR_21290	6.873e-108	383.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2M9PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158380_k127_1778909_5	861299.J421_3387	2.937e-36	139.0	COG0519@1|root,COG0519@2|Bacteria,1ZSMF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158380_k127_1781532_4	1267534.KB906754_gene3165	1.831e-07	55.0	COG2318@1|root,COG2318@2|Bacteria,3Y7B7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158380_k127_1781532_0	1535422.ND16A_3697	8.725e-53	194.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,2Q8AC@267889|Colwelliaceae	1236|Gammaproteobacteria	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158380_k127_1781532_2	1267534.KB906756_gene299	8.777e-30	125.0	29PQU@1|root,30AP1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
SRR25158380_k127_1781532_1	749414.SBI_02860	2.404e-42	173.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
SRR25158380_k127_1787887_4	1087448.Eab7_1306	0.0002033	49.0	COG1802@1|root,COG1802@2|Bacteria,1V9M8@1239|Firmicutes,4IQ0G@91061|Bacilli	91061|Bacilli	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158380_k127_1787887_0	749414.SBI_06433	1.262e-110	377.0	COG0520@1|root,COG0520@2|Bacteria,2H9MG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158380_k127_1787887_3	518766.Rmar_0540	1.681e-64	227.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1FJCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRR25158380_k127_1787887_2	379066.GAU_2113	2.071e-89	307.0	COG4181@1|root,COG4181@2|Bacteria,1ZUJS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_1787887_1	379066.GAU_2114	2.191e-90	318.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1821962_0	861299.J421_0464	7.535e-146	479.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158380_k127_1826391_0	883080.HMPREF9697_00890	1.44e-253	793.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JX36@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158380_k127_1826391_5	1535287.JP74_07995	1.849e-31	125.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,3N90Q@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158380_k127_1826391_2	861299.J421_4178	1.704e-126	415.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SRR25158380_k127_1826391_4	1157708.KB907450_gene5649	5.172e-32	131.0	COG2913@1|root,COG2913@2|Bacteria,1RJS2@1224|Proteobacteria,2VW4K@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Protein of unknown function (DUF3574)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3574
SRR25158380_k127_1826391_1	215803.DB30_0398	1.707e-167	538.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,2YWBV@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158380_k127_1826391_3	1379270.AUXF01000001_gene2144	8.043e-59	209.0	COG0491@1|root,COG2234@1|root,COG0491@2|Bacteria,COG2234@2|Bacteria,1ZT1R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158380_k127_1842976_0	861299.J421_5990	5.725e-157	503.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_1842976_2	313612.L8106_09571	3.332e-39	160.0	COG3011@1|root,COG3011@2|Bacteria,1GBBP@1117|Cyanobacteria,1HDV0@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
SRR25158380_k127_1842976_3	379066.GAU_2021	3.709e-26	121.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,VPEP
SRR25158380_k127_1842976_1	143224.JQMD01000002_gene3284	1.105e-42	174.0	COG0657@1|root,COG0657@2|Bacteria,4NGAF@976|Bacteroidetes,1HZ5F@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF1460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460
SRR25158380_k127_1842976_4	1869.MB27_34095	2.71e-08	60.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria,4DEWE@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158380_k127_1846723_3	861299.J421_4475	4.075e-07	55.0	2CA9X@1|root,2ZJY8@2|Bacteria,1ZU1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1846723_1	379066.GAU_0167	2.1e-22	99.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR25158380_k127_1846723_2	439235.Dalk_5198	5.477e-09	67.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
SRR25158380_k127_1846723_0	1191523.MROS_1573	1.687e-54	208.0	COG0077@1|root,COG1605@1|root,COG2876@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,COG2876@2|Bacteria	2|Bacteria	E	3-deoxy-7-phosphoheptulonate synthase activity	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,2.3.1.79,2.5.1.54,4.2.1.51,5.4.99.5	ko:K00661,ko:K03856,ko:K04092,ko:K04093,ko:K04516,ko:K04518,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R00691,R01373,R01715,R01728,R01826	RC00125,RC00360,RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_2667	ACT,CM_2,PDT
SRR25158380_k127_1858241_0	861299.J421_3101	2.249e-166	548.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158380_k127_1858241_1	379066.GAU_1453	5.305e-26	121.0	2EYUI@1|root,33S1Q@2|Bacteria,1ZTHR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1858241_2	379066.GAU_1452	1.143e-07	63.0	2F0K0@1|root,33TNP@2|Bacteria,1ZTJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_18710_1	1254432.SCE1572_33565	2.188e-48	177.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158380_k127_18710_0	861299.J421_6079	2.22e-85	293.0	COG4242@1|root,COG4242@2|Bacteria,1ZUD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	PQ	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158380_k127_18710_2	243231.GSU0698	6.552e-19	101.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158380_k127_1883646_1	449447.MAE_32340	0.0001393	52.0	COG5549@1|root,COG5549@2|Bacteria,1G4CD@1117|Cyanobacteria	1117|Cyanobacteria	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SRR25158380_k127_1883646_0	861299.J421_3762	1.049e-98	331.0	COG0648@1|root,COG0648@2|Bacteria,1ZSY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158380_k127_1918066_2	379066.GAU_1730	3.714e-36	143.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_1918066_0	379066.GAU_1731	2.898e-169	553.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158380_k127_1918066_1	189753.AXAS01000027_gene2991	5.41e-62	237.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TS0T@28211|Alphaproteobacteria,3JRJ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC2	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158380_k127_1931261_2	1283300.ATXB01000001_gene1628	5.317e-71	252.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1XDX5@135618|Methylococcales	135618|Methylococcales	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158380_k127_1931261_1	861299.J421_2824	6.629e-121	399.0	COG4948@1|root,COG4948@2|Bacteria,1ZSKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158380_k127_1931261_0	861299.J421_2825	3.567e-232	751.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR25158380_k127_1950856_1	861299.J421_0867	1.471e-121	422.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_0867|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_1950856_0	518766.Rmar_2129	1.916e-203	643.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1FIWI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_1950856_3	1396141.BATP01000030_gene3540	7.913e-26	113.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158380_k127_1950856_5	1232410.KI421412_gene421	7.449e-08	60.0	2EBKH@1|root,335KX@2|Bacteria,1NAWH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1950856_2	1123368.AUIS01000001_gene1895	2.137e-64	229.0	COG1073@1|root,COG1073@2|Bacteria,1RM16@1224|Proteobacteria,1S84X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158380_k127_1965759_0	861299.J421_0858	3.283e-48	181.0	COG1596@1|root,COG1596@2|Bacteria,1ZUC0@142182|Gemmatimonadetes	2|Bacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158380_k127_1965759_1	926550.CLDAP_04560	6.971e-45	185.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1965759_2	383372.Rcas_1839	3.992e-39	156.0	COG0438@1|root,COG0438@2|Bacteria,2G7TE@200795|Chloroflexi,3750Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1969978_0	926569.ANT_13370	5.298e-118	391.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158380_k127_1969978_1	1278073.MYSTI_07029	2.249e-18	98.0	28UXW@1|root,2ZH1P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1975524_1	1123073.KB899242_gene1384	2.743e-47	179.0	COG0454@1|root,COG0456@2|Bacteria,1RDH4@1224|Proteobacteria,1SCMT@1236|Gammaproteobacteria,1X66P@135614|Xanthomonadales	135614|Xanthomonadales	K	acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158380_k127_1975524_3	1242864.D187_004866	7.932e-31	132.0	COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,4358I@68525|delta/epsilon subdivisions,2WZJK@28221|Deltaproteobacteria,2Z29U@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158380_k127_1975524_2	518766.Rmar_1926	6.705e-41	154.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158380_k127_1975524_0	1123508.JH636450_gene7226	4.056e-54	196.0	COG1607@1|root,COG1607@2|Bacteria,2J16W@203682|Planctomycetes	203682|Planctomycetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158380_k127_19806_0	1122919.KB905555_gene879	1.592e-296	932.0	COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4HE8W@91061|Bacilli,26U7B@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
SRR25158380_k127_1985096_6	1254432.SCE1572_07160	3.555e-21	106.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2WRJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158380_k127_1985096_1	1379270.AUXF01000007_gene919	5.04e-78	273.0	COG5587@1|root,COG5587@2|Bacteria,1ZTH8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158380_k127_1985096_0	861299.J421_3958	2.655e-78	266.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
SRR25158380_k127_1985096_2	861299.J421_4041	1.184e-55	202.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158380_k127_1985096_4	861299.J421_1054	9.02e-39	167.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
SRR25158380_k127_1985096_5	1379270.AUXF01000003_gene3372	3.717e-38	146.0	COG1188@1|root,COG1188@2|Bacteria,1ZTXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRR25158380_k127_1985096_3	518766.Rmar_1401	1.84e-47	171.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1FJ4C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_1988715_3	765420.OSCT_2288	4.01e-57	218.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,375BG@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158380_k127_1988715_1	379066.GAU_0477	7.381e-90	309.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_1988715_0	861299.J421_2864	6.296e-120	397.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
SRR25158380_k127_1988715_2	1265505.ATUG01000002_gene1562	3.645e-67	241.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2MIQM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158380_k127_1990365_2	1356852.N008_14430	7.442e-67	239.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,47MN0@768503|Cytophagia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
SRR25158380_k127_1990365_3	326424.FRAAL2149	2.331e-27	117.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158380_k127_1990365_0	290397.Adeh_0831	4.173e-222	701.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YU0C@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158380_k127_1990365_5	1437824.BN940_02361	1.727e-05	55.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1990365_1	522306.CAP2UW1_1327	1.903e-71	261.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,Fer4_7,FlpD
SRR25158380_k127_1990825_2	926556.Echvi_2966	1.269e-05	52.0	COG0438@1|root,COG0438@2|Bacteria,4NMHX@976|Bacteroidetes,47VFA@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1990825_0	1380394.JADL01000013_gene800	4.228e-138	454.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,2U3BD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158380_k127_1990825_1	1123242.JH636434_gene3763	3.875e-30	126.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158380_k127_2003956_0	1128421.JAGA01000003_gene3726	4.576e-197	637.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldA	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130,ko:K00138	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158380_k127_2003956_1	1128421.JAGA01000003_gene3727	1.89e-159	508.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158380_k127_2003956_2	861299.J421_3849	2.175e-128	441.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_2003956_3	472759.Nhal_1932	3.821e-17	83.0	2E7PS@1|root,3325B@2|Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2011723_1	379066.GAU_0648	2.435e-34	140.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Peptidase_S74
SRR25158380_k127_2011723_3	861299.J421_2595	2.839e-21	103.0	2F73W@1|root,33ZJG@2|Bacteria,1ZTT7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2011723_0	861299.J421_2594	2.33e-84	292.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158380_k127_2011723_2	379066.GAU_0156	2.11e-26	112.0	COG1438@1|root,COG1438@2|Bacteria,1ZU02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158380_k127_2021622_1	215803.DB30_2637	1.034e-171	552.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria,2YTX2@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
SRR25158380_k127_2021622_4	1278073.MYSTI_04863	1.274e-38	162.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158380_k127_2021622_2	1379270.AUXF01000005_gene655	1.221e-68	248.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158380_k127_2021622_0	861299.J421_3042	9.1e-264	827.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SRR25158380_k127_2021622_3	861299.J421_3043	4.736e-61	237.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
SRR25158380_k127_2043513_1	452637.Oter_1158	4.06e-32	128.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2043513_0	1123508.JH636440_gene2646	1.431e-114	405.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2043513_2	861299.J421_0333	2.538e-22	104.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158380_k127_2047691_0	794903.OPIT5_07150	3.681e-73	257.0	COG4120@1|root,COG4120@2|Bacteria,46YK2@74201|Verrucomicrobia,3K9RK@414999|Opitutae	414999|Opitutae	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
SRR25158380_k127_2047691_1	794903.OPIT5_07145	2.216e-53	207.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
SRR25158380_k127_2047691_2	794903.OPIT5_07140	4.72e-47	184.0	COG2984@1|root,COG2984@2|Bacteria,46YPH@74201|Verrucomicrobia,3K9XT@414999|Opitutae	414999|Opitutae	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158380_k127_2049439_0	1379270.AUXF01000007_gene1047	1.825e-133	439.0	COG0635@1|root,COG0635@2|Bacteria,1ZUPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_2049439_4	1379270.AUXF01000001_gene1903	8.272e-47	178.0	2E0KI@1|root,32W5X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2049439_2	379066.GAU_1387	6.187e-53	203.0	COG3278@1|root,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2049439_1	627192.SLG_37070	2.698e-97	327.0	2DTTJ@1|root,32UVW@2|Bacteria,1NGQC@1224|Proteobacteria,2UKGP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158380_k127_2049439_3	1335757.SPICUR_04075	9.434e-53	194.0	COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
SRR25158380_k127_205015_2	502025.Hoch_3579	2.329e-09	60.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2YWK3@29|Myxococcales	28221|Deltaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158380_k127_205015_0	861299.J421_3866	1.444e-105	370.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_205015_1	861299.J421_3864	3.199e-93	319.0	COG2804@1|root,COG2804@2|Bacteria,1ZT2F@142182|Gemmatimonadetes	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158380_k127_2067075_5	1232428.CAVO010000023_gene1699	1.621e-09	64.0	COG1538@1|root,COG1538@2|Bacteria,1TRDS@1239|Firmicutes,4H2S7@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_2067075_1	497321.C664_04966	3.014e-57	219.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,2KVQF@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR25158380_k127_2067075_2	349124.Hhal_0101	1.802e-48	196.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WXZK@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_2067075_0	861299.J421_2921	2.942e-60	226.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158380_k127_2067075_4	379066.GAU_0141	3.039e-21	98.0	COG3794@1|root,COG3794@2|Bacteria,1ZTTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
SRR25158380_k127_2067075_6	1288963.ADIS_4816	1.952e-06	55.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	LysM,PD40
SRR25158380_k127_2067075_3	1379270.AUXF01000002_gene1823	9.898e-46	180.0	COG0840@1|root,COG0840@2|Bacteria,1ZSWC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRR25158380_k127_2082348_0	861299.J421_3116	2.521e-167	532.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158380_k127_2082348_3	861299.J421_3115	2.308e-52	203.0	COG0307@1|root,COG0307@2|Bacteria,1ZTQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158380_k127_2082348_2	379066.GAU_1471	3.384e-81	282.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158380_k127_2082348_4	861299.J421_3113	2.659e-28	126.0	2F30H@1|root,33VVT@2|Bacteria,1ZTRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2082348_1	861299.J421_3112	7.26e-107	355.0	COG0150@1|root,COG0150@2|Bacteria,1ZSQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_2096332_2	379066.GAU_1190	1.977e-27	123.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
SRR25158380_k127_2096332_0	379066.GAU_1191	1.384e-142	460.0	COG2876@1|root,COG2876@2|Bacteria,1ZTB0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158380_k127_2096332_1	1379270.AUXF01000005_gene505	2.711e-112	379.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158380_k127_2096890_4	448385.sce7844	9.699e-46	189.0	COG0463@1|root,COG1541@1|root,COG0463@2|Bacteria,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glycos_transf_2
SRR25158380_k127_2096890_1	338963.Pcar_2907	4.819e-89	307.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,42PZT@68525|delta/epsilon subdivisions,2WMN6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
SRR25158380_k127_2096890_2	1089551.KE386572_gene401	1.924e-66	256.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,4BSZB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SRR25158380_k127_2096890_3	644968.DFW101_2097	8.177e-61	230.0	COG0438@1|root,COG0438@2|Bacteria,1RH5W@1224|Proteobacteria,42UY3@68525|delta/epsilon subdivisions,2WQ9B@28221|Deltaproteobacteria,2MA2D@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2096890_5	661478.OP10G_2768	1.756e-25	110.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158380_k127_2096890_0	861299.J421_6111	4.565e-96	325.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2097731_2	379066.GAU_2991	2.085e-49	194.0	COG0845@1|root,COG0845@2|Bacteria,1ZUDM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR25158380_k127_2097731_4	887062.HGR_07546	1.451e-20	101.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,4AA6X@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
SRR25158380_k127_2097731_3	1128421.JAGA01000001_gene2006	8.275e-44	173.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
SRR25158380_k127_2097731_1	580332.Slit_2572	6.476e-51	192.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2097731_0	861299.J421_3818	6.242e-87	290.0	COG1028@1|root,COG1028@2|Bacteria,1ZT7P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_2107433_3	1379270.AUXF01000002_gene1389	1.584e-05	57.0	2EY2H@1|root,33RBE@2|Bacteria,1ZTHK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2107433_1	861299.J421_2393	2.099e-54	201.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
SRR25158380_k127_2107433_0	861299.J421_2390	7.354e-110	365.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_2107433_2	1095769.CAHF01000009_gene1408	1.762e-26	127.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,473F1@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158380_k127_2107943_1	231434.JQJH01000001_gene1857	3.99e-15	85.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,1RG3J@1224|Proteobacteria,2U7QD@28211|Alphaproteobacteria,3NBV8@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158380_k127_2107943_2	1234364.AMSF01000088_gene2731	2.303e-11	70.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,1SCRY@1236|Gammaproteobacteria,1X8SI@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158380_k127_2107943_0	671143.DAMO_2883	2.266e-66	241.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158380_k127_2112013_3	58123.JOFJ01000019_gene3877	1.686e-39	151.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria,4EIVW@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2112013_0	713587.THITH_03495	6.705e-197	650.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1WX9G@135613|Chromatiales	135613|Chromatiales	C	PFAM Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
SRR25158380_k127_2112013_1	234267.Acid_7338	4.977e-126	428.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_2112013_2	1121930.AQXG01000011_gene1720	2.381e-61	218.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_2115897_3	234267.Acid_4617	1.591e-70	254.0	COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
SRR25158380_k127_2115897_0	316067.Geob_1385	6.377e-129	426.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158380_k127_2115897_2	518766.Rmar_0400	1.974e-109	376.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1FJY0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
SRR25158380_k127_2115897_1	861299.J421_6272	7.268e-114	378.0	28MSW@1|root,2ZB15@2|Bacteria,1ZUI9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2120182_0	1125863.JAFN01000001_gene1858	7.484e-98	335.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_2120182_1	1210884.HG799462_gene8941	5.563e-80	275.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158380_k127_2120206_1	485913.Krac_11442	6.754e-68	238.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158380_k127_2120206_0	861299.J421_4190	6.799e-72	250.0	COG0755@1|root,COG0755@2|Bacteria,1ZTJG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158380_k127_2120206_2	861299.J421_4191	1.798e-58	209.0	COG2386@1|root,COG2386@2|Bacteria,1ZTJ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158380_k127_2121124_3	379066.GAU_0609	1.425e-21	113.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158380_k127_2121124_0	518766.Rmar_0703	4.965e-97	344.0	COG4775@1|root,COG4775@2|Bacteria,4NR0H@976|Bacteroidetes,1FIVR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158380_k127_2121124_1	1254432.SCE1572_35555	2.537e-72	265.0	COG1801@1|root,COG1801@2|Bacteria,1N06I@1224|Proteobacteria,43BIA@68525|delta/epsilon subdivisions,2X6WP@28221|Deltaproteobacteria,2Z3DC@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_2121124_2	1242864.D187_009605	4.761e-63	238.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
SRR25158380_k127_2128440_3	861299.J421_2179	7.174e-36	140.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158380_k127_2128440_2	379066.GAU_0431	4.026e-67	247.0	COG5276@1|root,COG5276@2|Bacteria,1ZUNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158380_k127_2128440_1	861299.J421_2036	4.879e-74	271.0	2EXQQ@1|root,33R07@2|Bacteria,1ZUK8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2128440_0	861299.J421_3298	4.597e-88	293.0	COG0479@1|root,COG0479@2|Bacteria,1ZT02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158380_k127_2133241_1	272630.MexAM1_META1p2575	1.03e-14	79.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U1FV@28211|Alphaproteobacteria,1JT8R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158380_k127_2133241_0	639030.JHVA01000001_gene2023	1.577e-100	340.0	COG3391@1|root,COG3391@2|Bacteria,3Y3TB@57723|Acidobacteria,2JKB3@204432|Acidobacteriia	204432|Acidobacteriia	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158380_k127_2133241_2	378806.STAUR_6504	1.794e-09	64.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YYTH@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	prlC1	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158380_k127_2169365_0	379066.GAU_2373	1.55e-120	407.0	COG0306@1|root,COG0306@2|Bacteria,1ZSZ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158380_k127_2169365_1	861299.J421_3846	8.223e-56	201.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158380_k127_2169365_2	485913.Krac_4466	6.65e-52	198.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2G8HF@200795|Chloroflexi	2|Bacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2175945_0	1147.D082_17450	1.757e-165	554.0	COG0272@1|root,COG0272@2|Bacteria,1G12K@1117|Cyanobacteria,1H4JA@1142|Synechocystis	1117|Cyanobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158380_k127_2175945_2	1242864.D187_002804	2.519e-19	97.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,4304I@68525|delta/epsilon subdivisions,2WVDN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	sensor histidine kinase response	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,Response_reg
SRR25158380_k127_2175945_1	861299.J421_2718	1.592e-23	103.0	COG0457@1|root,COG0457@2|Bacteria,1ZTR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2176787_6	1266914.ATUK01000001_gene783	4.346e-07	54.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158380_k127_2176787_0	1379270.AUXF01000004_gene3254	7.521e-140	466.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158380_k127_2176787_4	861299.J421_2579	2.918e-46	179.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158380_k127_2176787_3	1379270.AUXF01000004_gene3248	1.093e-51	190.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158380_k127_2176787_1	1379270.AUXF01000004_gene3247	6.569e-91	306.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158380_k127_2176787_2	1125863.JAFN01000001_gene536	6.408e-58	216.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158380_k127_2176787_5	290317.Cpha266_2639	9.743e-26	111.0	2DNS7@1|root,32YWC@2|Bacteria,1FFKA@1090|Chlorobi	1090|Chlorobi	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_2184074_3	926550.CLDAP_16610	7.294e-06	54.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2G5VA@200795|Chloroflexi	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	1.5.3.1,2.1.2.10	ko:K00303,ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R00610,R01221,R02300,R04125	RC00022,RC00060,RC00069,RC00183,RC00557,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158380_k127_2184074_1	713586.KB900536_gene2816	2.712e-48	180.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158380_k127_2184074_2	1234364.AMSF01000013_gene680	1.014e-29	119.0	2E3AG@1|root,32Y9Z@2|Bacteria,1NADT@1224|Proteobacteria,1SDGA@1236|Gammaproteobacteria,1X89Q@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2184074_0	1379270.AUXF01000002_gene1164	3.129e-201	655.0	COG0249@1|root,COG0249@2|Bacteria,1ZST5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158380_k127_218411_1	861299.J421_4420	2.475e-21	95.0	COG0296@1|root,COG0296@2|Bacteria,1ZUZV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_218411_2	861299.J421_1305	8.923e-21	99.0	28YSJ@1|root,343H2@2|Bacteria,1ZU2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_218411_0	861299.J421_4538	9.413e-23	114.0	2C9AW@1|root,2ZVNX@2|Bacteria,1ZUAK@142182|Gemmatimonadetes	861299.J421_4538|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2185784_4	861299.J421_3562	1.152e-90	317.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	2|Bacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
SRR25158380_k127_2185784_2	379066.GAU_3212	2.139e-118	402.0	COG0006@1|root,COG0006@2|Bacteria,1ZUGP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158380_k127_2185784_0	713586.KB900536_gene2395	8.541e-146	467.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158380_k127_2185784_3	1173024.KI912149_gene6263	2.44e-95	321.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1GKR9@1117|Cyanobacteria,1JMKR@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_2185784_1	1123368.AUIS01000024_gene954	1.213e-143	471.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
SRR25158380_k127_2185784_5	652103.Rpdx1_1192	1.004e-55	211.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,3K48K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158380_k127_2185784_6	1255043.TVNIR_1670	9.416e-14	76.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,1X0DH@135613|Chromatiales	135613|Chromatiales	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SRR25158380_k127_2207976_0	861299.J421_2748	3.873e-137	441.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158380_k127_2207976_3	1198449.ACAM_1034	1.789e-06	57.0	COG2110@1|root,arCOG04225@2157|Archaea,2XQEQ@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158380_k127_2207976_1	1379270.AUXF01000004_gene3068	2.621e-97	332.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_2207976_2	1379270.AUXF01000004_gene3069	6.227e-80	277.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
SRR25158380_k127_2222352_1	1089551.KE386572_gene400	2.842e-47	190.0	COG2244@1|root,COG2244@2|Bacteria,1RFDD@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
SRR25158380_k127_2222352_5	1227488.C477_07458	2.918e-06	59.0	COG1247@1|root,arCOG00830@2157|Archaea,2Y88H@28890|Euryarchaeota,2416F@183963|Halobacteria	183963|Halobacteria	K	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_2222352_4	251221.35214612	2.326e-06	61.0	COG3146@1|root,COG3146@2|Bacteria,1G0U8@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
SRR25158380_k127_2222352_3	331678.Cphamn1_0115	6.126e-11	74.0	2E1K4@1|root,32WXM@2|Bacteria,1FF52@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2222352_0	335283.Neut_0907	5.55e-72	273.0	COG0193@1|root,COG0770@1|root,COG0193@2|Bacteria,COG0770@2|Bacteria,1RHXY@1224|Proteobacteria	1224|Proteobacteria	M	Mur ligase middle domain protein	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_M,Pept_tRNA_hydro
SRR25158380_k127_2222352_2	1169161.KB897716_gene6039	1.988e-19	102.0	COG0026@1|root,COG0026@2|Bacteria,2GNWR@201174|Actinobacteria	201174|Actinobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,CPSase_L_D2
SRR25158380_k127_2225849_0	1379270.AUXF01000003_gene3823	3.581e-165	528.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SRR25158380_k127_2225849_8	861299.J421_3628	1.443e-27	129.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SRR25158380_k127_2225849_9	379066.GAU_2033	3.273e-14	82.0	COG2010@1|root,COG2010@2|Bacteria,1ZTPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158380_k127_2225849_2	861299.J421_3626	2.745e-61	231.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2225849_6	1379270.AUXF01000001_gene2379	7.132e-33	138.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_2225849_7	1379270.AUXF01000002_gene1410	2.015e-32	143.0	COG3794@1|root,COG3794@2|Bacteria,1ZTTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
SRR25158380_k127_2225849_5	861299.J421_0797	3.371e-35	146.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	dgkA	-	2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K00901,ko:K01096,ko:K19302	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02029,R02240,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2,PAP2_3
SRR25158380_k127_2225849_3	448385.sce7198	9.8e-54	215.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158380_k127_2225849_1	1144275.COCOR_04256	8.223e-101	345.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2225849_4	861299.J421_0795	2.649e-49	179.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	2|Bacteria	H	Beta-eliminating lyase	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_223133_2	1380386.JIAW01000002_gene5536	7.647e-27	115.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,234UX@1762|Mycobacteriaceae	201174|Actinobacteria	S	glutamine amidotransferase	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158380_k127_223133_0	886293.Sinac_3851	2.038e-74	257.0	COG1926@1|root,COG1926@2|Bacteria,2J36S@203682|Planctomycetes	203682|Planctomycetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158380_k127_223133_1	1123487.KB892864_gene2093	3.13e-39	156.0	COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,2WA7C@28216|Betaproteobacteria,2KZM4@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_223133_3	1167006.UWK_03269	1.424e-21	102.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,42WD4@68525|delta/epsilon subdivisions,2WSEK@28221|Deltaproteobacteria,2MJCV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.3.1.111,1.3.1.83,1.3.99.38	ko:K10960,ko:K21401	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl
SRR25158380_k127_2237552_1	1380390.JIAT01000010_gene4321	2.42e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,2IAGY@201174|Actinobacteria	1380390.JIAT01000010_gene4321|-	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2237552_4	671143.DAMO_2674	9.854e-19	96.0	COG1891@1|root,COG1891@2|Bacteria	2|Bacteria	T	lyase activity	-	-	1.13.11.81,4.1.2.25,4.2.3.153,5.1.99.8	ko:K01633,ko:K09733	ko00680,ko00790,ko01100,map00680,map00790,map01100	M00126,M00840	R03504,R10935,R11037,R11073	RC00721,RC00943,RC01479,RC03315,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	4HFCP_synth,FolB
SRR25158380_k127_2237552_2	330214.NIDE0686	3.221e-53	215.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MEDS,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2237552_3	1301098.PKB_0528	1.726e-44	187.0	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
SRR25158380_k127_2237552_0	398767.Glov_0703	1.3e-78	271.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WUAW@28221|Deltaproteobacteria,43U3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
SRR25158380_k127_2247626_2	379066.GAU_1316	6.922e-121	404.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_2247626_1	379066.GAU_1315	1.065e-126	419.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
SRR25158380_k127_2247626_0	379066.GAU_1314	2.878e-128	414.0	COG3696@1|root,COG3696@2|Bacteria,1ZUB0@142182|Gemmatimonadetes	2|Bacteria	P	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SRR25158380_k127_2261813_0	861299.J421_2362	2.556e-42	160.0	COG0277@1|root,COG0277@2|Bacteria,1ZTB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158380_k127_2261813_1	1157490.EL26_01200	4.756e-33	138.0	COG1852@1|root,COG1852@2|Bacteria,1V1B5@1239|Firmicutes,4HUDI@91061|Bacilli,279H3@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
SRR25158380_k127_2273973_2	1489678.RDMS_05270	2.335e-06	49.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1WIBP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158380_k127_2273973_0	379066.GAU_0738	1.649e-76	273.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
SRR25158380_k127_2273973_1	292459.STH1238	5.894e-44	165.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes	1239|Firmicutes	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_2294558_0	404589.Anae109_3731	2.806e-196	637.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
SRR25158380_k127_2294558_1	1207063.P24_18591	1.496e-80	276.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,2TQZZ@28211|Alphaproteobacteria,2JPG0@204441|Rhodospirillales	204441|Rhodospirillales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158380_k127_2303012_0	1385935.N836_35030	5.549e-37	145.0	2DMJE@1|root,32RYR@2|Bacteria,1G6SI@1117|Cyanobacteria,1HBXF@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SRR25158380_k127_2303012_3	316067.Geob_0934	3.604e-22	103.0	COG0346@1|root,COG0346@2|Bacteria,1NPMU@1224|Proteobacteria,42TZ4@68525|delta/epsilon subdivisions,2WQKA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_2303012_1	861299.J421_0649	2.76e-29	130.0	COG0596@1|root,COG0596@2|Bacteria	861299.J421_0649|-	S	hydrolase activity, acting on ester bonds	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
SRR25158380_k127_2303012_2	861299.J421_1652	3.818e-23	99.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158380_k127_2313854_2	1169161.KB897714_gene6205	1.003e-78	282.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158380_k127_2313854_0	204669.Acid345_1535	5.602e-235	737.0	COG1012@1|root,COG1012@2|Bacteria,3Y384@57723|Acidobacteria,2JIA8@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85	ko:K00128,ko:K00130,ko:K00146,ko:K10217	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00555,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158380_k127_2313854_1	861299.J421_0271	2.193e-204	652.0	COG4585@1|root,COG4585@2|Bacteria,1ZSM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158380_k127_2313854_3	861299.J421_0272	4.435e-44	183.0	COG2197@1|root,COG2197@2|Bacteria,1ZTJ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_2323690_1	158500.BV97_02377	3.37e-106	365.0	COG2244@1|root,COG2244@2|Bacteria,1RIX0@1224|Proteobacteria,2UB6M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158380_k127_2323690_5	1123368.AUIS01000006_gene676	6.313e-19	94.0	2C12A@1|root,33B7C@2|Bacteria,1NMUW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2323690_3	215803.DB30_3428	1.851e-21	102.0	2E40T@1|root,32YXK@2|Bacteria,1N95U@1224|Proteobacteria,43E2C@68525|delta/epsilon subdivisions,2WZHB@28221|Deltaproteobacteria,2Z25B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2323690_4	1123368.AUIS01000006_gene674	1.865e-20	98.0	COG3682@1|root,COG3682@2|Bacteria,1N6UP@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2323690_2	1237149.C900_00088	7.909e-74	275.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,4NDUQ@976|Bacteroidetes,47PTN@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
SRR25158380_k127_2323690_0	756067.MicvaDRAFT_0974	2.804e-131	424.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G13T@1117|Cyanobacteria,1HI4W@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158380_k127_2328768_0	861299.J421_3942	3.742e-126	412.0	COG1208@1|root,COG1208@2|Bacteria,1ZSYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_2328768_1	457570.Nther_2188	3.318e-64	237.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158380_k127_2332025_2	41431.PCC8801_4425	3.59e-30	140.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGMH@43988|Cyanothece	1117|Cyanobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
SRR25158380_k127_2332025_0	443143.GM18_0309	8.312e-87	308.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg,dCache_1
SRR25158380_k127_2332025_1	1094980.Mpsy_2813	1.312e-40	165.0	COG0628@1|root,arCOG02642@2157|Archaea,2XT00@28890|Euryarchaeota,2NAEQ@224756|Methanomicrobia	224756|Methanomicrobia	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158380_k127_2345903_2	709797.CSIRO_4186	8.578e-68	236.0	COG0400@1|root,COG0400@2|Bacteria,1MUKQ@1224|Proteobacteria,2TUA0@28211|Alphaproteobacteria,3JTR9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_2
SRR25158380_k127_2345903_0	251229.Chro_1450	2.181e-112	372.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999,ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
SRR25158380_k127_2345903_1	1038858.AXBA01000006_gene893	1.468e-77	264.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3F1HK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_2365488_1	1265310.CCBD010000065_gene939	3.133e-66	233.0	COG0515@1|root,COG2199@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,2H5ZS@201174|Actinobacteria,232IX@1762|Mycobacteriaceae	2|Bacteria	KLT	PFAM Protein kinase	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheX,HATPase_c,HisKA,Response_reg
SRR25158380_k127_2365488_0	1300345.LF41_1458	1.96e-90	315.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HTH_20,Peptidase_M29
SRR25158380_k127_2372506_1	264732.Moth_2008	3.195e-96	324.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158380_k127_2372506_3	379066.GAU_0945	1.276e-54	209.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR25158380_k127_2372506_4	378806.STAUR_8288	6.066e-42	171.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria,2YZWN@29|Myxococcales	28221|Deltaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158380_k127_2372506_2	861299.J421_3181	1.186e-94	344.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
SRR25158380_k127_2372506_0	379066.GAU_1551	1.738e-180	574.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158380_k127_2374665_2	1144275.COCOR_04568	1.866e-12	68.0	COG2234@1|root,COG2234@2|Bacteria,1R77P@1224|Proteobacteria	1224|Proteobacteria	N	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158380_k127_2374665_0	644966.Tmar_1975	5.204e-60	226.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_2374665_1	861299.J421_3528	6.397e-21	98.0	COG0792@1|root,COG0792@2|Bacteria,1ZTWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158380_k127_2402313_8	1463917.JODC01000017_gene2414	3.237e-08	58.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_2402313_3	861299.J421_3591	2.892e-67	241.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_2402313_4	1379270.AUXF01000003_gene3868	1.938e-62	224.0	2AEWX@1|root,314UJ@2|Bacteria,1ZUPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2402313_2	1196324.A374_02169	3.872e-83	293.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_2402313_5	1125863.JAFN01000001_gene1846	5.831e-51	198.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_2402313_0	379066.GAU_0686	2.628e-132	436.0	COG0438@1|root,COG0438@2|Bacteria,1ZUNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase Family 4	-	-	-	ko:K14335	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158380_k127_2402313_7	1379270.AUXF01000007_gene927	1.596e-08	65.0	COG0392@1|root,COG0392@2|Bacteria,1ZSUQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158380_k127_2402313_6	266117.Rxyl_2863	3.162e-21	98.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR25158380_k127_2402313_1	1379270.AUXF01000003_gene3872	8.169e-94	313.0	COG1027@1|root,COG1027@2|Bacteria,1ZSUY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158380_k127_2403170_2	861299.J421_4333	3.622e-23	109.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158380_k127_2403170_4	1123237.Salmuc_02296	1.35e-06	60.0	COG0517@1|root,COG0517@2|Bacteria,1Q3MP@1224|Proteobacteria,2UB19@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2403170_3	512565.AMIS_43390	1.626e-12	79.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,4DCP2@85008|Micromonosporales	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158380_k127_2403170_1	379066.GAU_2699	3.956e-31	132.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158380_k127_2403170_0	861299.J421_4453	5.814e-120	390.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1ZTC2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158380_k127_2407164_6	1166018.FAES_1547	7.051e-10	59.0	COG1249@1|root,COG1249@2|Bacteria,4NEMS@976|Bacteroidetes,47KQ1@768503|Cytophagia	976|Bacteroidetes	C	Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)	merA	-	-	ko:K21739	-	-	-	-	ko00000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_2407164_0	266117.Rxyl_0687	4.312e-148	481.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
SRR25158380_k127_2407164_2	68260.JOAY01000001_gene3599	1.936e-80	282.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158380_k127_2407164_3	105425.BBPL01000040_gene3434	7.693e-52	207.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,2NG8H@228398|Streptacidiphilus	201174|Actinobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SRR25158380_k127_2407164_4	1395587.P364_0111400	8.917e-22	111.0	COG3861@1|root,COG3861@2|Bacteria,1V5RZ@1239|Firmicutes,4HHAU@91061|Bacilli,26SHD@186822|Paenibacillaceae	91061|Bacilli	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	YflT
SRR25158380_k127_2407164_1	926550.CLDAP_27360	4.407e-124	405.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_2407164_5	365046.Rta_19265	6.868e-19	93.0	COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria,4AIYX@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_2412284_3	861299.J421_3153	3.677e-65	251.0	COG2304@1|root,COG2304@2|Bacteria,1ZTCZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
SRR25158380_k127_2412284_1	379066.GAU_1527	1.717e-97	336.0	COG2304@1|root,COG2304@2|Bacteria,1ZSVY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1194)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SRR25158380_k127_2412284_2	861299.J421_3151	5.76e-90	306.0	COG1721@1|root,COG1721@2|Bacteria,1ZSKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158380_k127_2412284_0	861299.J421_3150	4.589e-143	460.0	COG0714@1|root,COG0714@2|Bacteria,1ZT94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158380_k127_2443673_1	1463881.KL591023_gene3570	4.013e-13	72.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2443673_0	1173025.GEI7407_0649	5.173e-51	196.0	COG0438@1|root,COG0438@2|Bacteria,1G291@1117|Cyanobacteria,1H7YZ@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2443673_2	1089551.KE386572_gene2693	3.897e-08	62.0	COG4106@1|root,COG4106@2|Bacteria,1R04W@1224|Proteobacteria,2U5VR@28211|Alphaproteobacteria,4BS2C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_244667_4	338966.Ppro_2460	3.707e-31	132.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_244667_2	330214.NIDE0769	9.065e-48	185.0	COG0325@1|root,COG0325@2|Bacteria,3J0RJ@40117|Nitrospirae	40117|Nitrospirae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158380_k127_244667_1	1379270.AUXF01000005_gene660	1.197e-61	229.0	COG0005@1|root,COG0005@2|Bacteria,1ZUII@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158380_k127_244667_3	1379270.AUXF01000005_gene660	2.137e-39	149.0	COG0005@1|root,COG0005@2|Bacteria,1ZUII@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158380_k127_244667_0	861299.J421_3048	1.166e-97	338.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_2454076_0	1442599.JAAN01000024_gene1820	1.922e-120	400.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1SZTS@1236|Gammaproteobacteria,1X4EA@135614|Xanthomonadales	135614|Xanthomonadales	V	abc transporter atp-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158380_k127_2454076_2	869210.Marky_1948	2.677e-44	175.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_2454076_1	926569.ANT_11780	3.066e-64	240.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158380_k127_2458258_13	1144275.COCOR_02637	3.316e-13	71.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158380_k127_2458258_2	316067.Geob_3386	3.537e-92	326.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Signal transducing histidine kinase homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158380_k127_2458258_10	316067.Geob_3385	4.164e-28	121.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42QS2@68525|delta/epsilon subdivisions,2WMXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158380_k127_2458258_6	316067.Geob_3384	6.911e-58	221.0	COG0840@1|root,COG1511@1|root,COG0840@2|Bacteria,COG1511@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2WM8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
SRR25158380_k127_2458258_12	448385.sce2660	1.402e-18	102.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,2YU62@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
SRR25158380_k127_2458258_7	290397.Adeh_2731	8.506e-45	184.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,2YUW4@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR25158380_k127_2458258_4	292459.STH1541	1.997e-66	253.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158380_k127_2458258_1	592015.HMPREF1705_02114	3.654e-104	347.0	COG0115@1|root,COG0115@2|Bacteria,3T9VI@508458|Synergistetes	508458|Synergistetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158380_k127_2458258_11	517722.AEUE01000008_gene138	1.794e-26	124.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,2TT1J@28211|Alphaproteobacteria,2K5EH@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064
SRR25158380_k127_2458258_14	379066.GAU_2229	3.045e-11	69.0	2960H@1|root,2ZTB5@2|Bacteria,1ZU7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2458258_3	1125863.JAFN01000001_gene2180	4.772e-83	297.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158380_k127_2458258_9	379066.GAU_2227	4.597e-30	128.0	COG0741@1|root,COG0741@2|Bacteria,1ZTV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158380_k127_2458258_8	1247963.JPHU01000013_gene627	6.248e-43	174.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158380_k127_2458258_5	861299.J421_3797	1.293e-61	226.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158380_k127_2458258_0	219305.MCAG_04417	2.024e-134	440.0	COG0477@1|root,COG0477@2|Bacteria,2IIAH@201174|Actinobacteria,4D9T1@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158380_k127_2462089_1	309801.trd_1102	1.065e-16	94.0	COG1999@1|root,COG1999@2|Bacteria,2GAE4@200795|Chloroflexi,27YPG@189775|Thermomicrobia	189775|Thermomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158380_k127_2462089_0	1244869.H261_01547	9.576e-93	313.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2U068@28211|Alphaproteobacteria,2JWSB@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRR25158380_k127_2468069_2	861299.J421_1729	1.872e-63	237.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2468069_0	861299.J421_3960	1.067e-139	449.0	COG0078@1|root,COG0078@2|Bacteria,1ZT4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158380_k127_2468069_1	861299.J421_3957	4.032e-78	268.0	COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158380_k127_2468722_0	483219.LILAB_34335	1.817e-38	156.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRR25158380_k127_2468722_1	759362.KVU_1965	3.038e-13	72.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2488651_0	861299.J421_3571	0.0	1310.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158380_k127_2488651_1	1122919.KB905550_gene1896	6.768e-63	228.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRR25158380_k127_2500396_4	472759.Nhal_3311	7.712e-24	106.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158380_k127_2500396_0	1379270.AUXF01000004_gene3104	2.74e-249	786.0	COG0433@1|root,COG0433@2|Bacteria,1ZURZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_2500396_2	861299.J421_2696	1.677e-115	384.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
SRR25158380_k127_2500396_1	861299.J421_2697	1.311e-160	541.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158380_k127_2500396_3	1379270.AUXF01000004_gene3100	1.028e-60	213.0	COG0454@1|root,COG0454@2|Bacteria,1ZSVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_2504936_0	1521187.JPIM01000045_gene1444	7.799e-207	655.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158380_k127_2504936_3	1203554.HMPREF1476_00230	1.927e-11	72.0	COG2378@1|root,COG2378@2|Bacteria,1Q17A@1224|Proteobacteria,2W688@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2504936_2	1123368.AUIS01000029_gene1283	9.422e-63	220.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,2NCU3@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158380_k127_2504936_1	1123392.AQWL01000006_gene602	1.042e-136	454.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KRAF@119069|Hydrogenophilales	119069|Hydrogenophilales	F	ATP-grasp domain	-	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158380_k127_2517953_3	926566.Terro_0874	2.73e-48	181.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRR25158380_k127_2517953_4	251221.35213986	2.062e-29	134.0	COG1310@1|root,COG1310@2|Bacteria,1G7SZ@1117|Cyanobacteria	1117|Cyanobacteria	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158380_k127_2517953_0	357808.RoseRS_0720	1.587e-91	311.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi,376HR@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2517953_2	379066.GAU_1983	2.725e-56	200.0	COG1959@1|root,COG1959@2|Bacteria,1ZTRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158380_k127_2517953_1	1095769.CAHF01000006_gene1870	1.591e-89	302.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2VKPI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158380_k127_2526055_1	1382306.JNIM01000001_gene1511	1.96e-25	119.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,TPR_8
SRR25158380_k127_2526055_2	1196083.SALWKB12_2086	8.545e-05	51.0	COG1361@1|root,COG1404@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,1R00J@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2526055_0	861299.J421_1666	5.559e-114	400.0	COG0515@1|root,COG0515@2|Bacteria,1ZUM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2558146_3	379066.GAU_1741	7.037e-45	167.0	COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
SRR25158380_k127_2558146_2	1123277.KB893206_gene3282	2.693e-74	267.0	COG3386@1|root,COG3386@2|Bacteria,4PKKP@976|Bacteroidetes,47RQ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158380_k127_2558146_0	1379270.AUXF01000006_gene148	2.164e-125	418.0	COG0042@1|root,COG0042@2|Bacteria,1ZSQC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158380_k127_2558146_1	401053.AciPR4_1688	7.572e-76	268.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158380_k127_2558146_4	929556.Solca_0532	8.95e-25	112.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1IQ7A@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM CorA-like Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158380_k127_2562280_3	944479.JQLX01000011_gene928	2.162e-37	144.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2M6TU@213113|Desulfurellales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_2562280_6	1244869.H261_07603	1.447e-19	95.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,2JTAQ@204441|Rhodospirillales	204441|Rhodospirillales	S	sulfur oxidation protein (SoxY)	-	-	-	-	-	-	-	-	-	-	-	-	SoxY
SRR25158380_k127_2562280_5	156889.Mmc1_3715	3.984e-20	100.0	COG2033@1|root,COG2033@2|Bacteria,1QVWP@1224|Proteobacteria,2TWVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
SRR25158380_k127_2562280_4	1163617.SCD_n02222	1.193e-35	150.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VM8B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_2562280_1	41431.PCC8801_4279	2.144e-48	194.0	COG2897@1|root,COG2897@2|Bacteria,1G26U@1117|Cyanobacteria,3KH98@43988|Cyanothece	1117|Cyanobacteria	P	PFAM Rhodanese domain protein	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_2562280_2	1122137.AQXF01000002_gene649	2.126e-41	171.0	COG1228@1|root,COG1228@2|Bacteria,1R86X@1224|Proteobacteria,2U400@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_2562280_0	926560.KE387027_gene562	4.795e-101	334.0	COG0113@1|root,COG0113@2|Bacteria,1WINH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158380_k127_256344_5	861299.J421_1216	6.232e-27	121.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158380_k127_256344_0	379066.GAU_2804	1.781e-167	547.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158380_k127_256344_7	1379270.AUXF01000001_gene2507	4.185e-11	66.0	2FCBU@1|root,344FF@2|Bacteria,1ZU39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_256344_3	592015.HMPREF1705_01539	1.103e-60	223.0	COG0693@1|root,COG0693@2|Bacteria,3TB17@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158380_k127_256344_4	1379270.AUXF01000001_gene2089	6.642e-45	176.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	ypjD	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	MazG
SRR25158380_k127_256344_2	1379270.AUXF01000001_gene2472	4.997e-77	273.0	COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158380_k127_256344_6	1379270.AUXF01000001_gene2471	1.436e-13	76.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_256344_1	861299.J421_4533	1.221e-112	371.0	COG0506@1|root,COG0506@2|Bacteria,1ZT6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158380_k127_256682_6	485913.Krac_4915	3.711e-88	297.0	COG1249@1|root,COG1249@2|Bacteria,2G5VW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	merA	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_256682_0	383372.Rcas_1551	2.815e-235	736.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,3758Q@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158380_k127_256682_7	886293.Sinac_5288	1.019e-35	143.0	COG2166@1|root,COG2166@2|Bacteria,2J0TJ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Fe-S metabolism associated	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
SRR25158380_k127_256682_4	399795.CtesDRAFT_PD1472	1.995e-107	367.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,4ABJZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158380_k127_256682_3	760192.Halhy_5945	2.053e-114	385.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1IWPE@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_256682_2	589865.DaAHT2_0797	1.278e-122	403.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2MIJH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158380_k127_256682_1	1035308.AQYY01000001_gene2783	5.062e-133	438.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158380_k127_256682_5	452637.Oter_3628	5.114e-102	339.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158380_k127_2577005_4	1051632.TPY_0985	4.584e-26	123.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_2577005_0	1379270.AUXF01000004_gene3120	3.022e-110	368.0	COG0444@1|root,COG0444@2|Bacteria,1ZSWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_2577005_1	861299.J421_2681	3.335e-72	266.0	COG1173@1|root,COG1173@2|Bacteria,1ZTMP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158380_k127_2577005_2	667014.Thein_0118	1.694e-69	251.0	COG0601@1|root,COG0601@2|Bacteria,2GHD2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158380_k127_2577005_3	861299.J421_3721	2.632e-61	228.0	COG0747@1|root,COG0747@2|Bacteria,1ZUDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158380_k127_258980_1	861299.J421_6055	6.091e-177	569.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	2.1.1.242,2.1.1.303,2.1.1.319	ko:K11434,ko:K15984,ko:K20421	ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922	M00830	R10963,R11216,R11217,R11219	RC00003,RC00392,RC02120,RC03388,RC03390	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	-	-	-	DOT1,Methyltransf_21,Methyltransf_25
SRR25158380_k127_258980_0	1192034.CAP_8820	3.463e-184	588.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158380_k127_258980_3	1128421.JAGA01000001_gene2398	6.564e-74	259.0	COG0124@1|root,COG0124@2|Bacteria	2|Bacteria	J	histidine-tRNA ligase activity	hisZ	-	6.1.1.21	ko:K01892,ko:K02502	ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230	M00026,M00359,M00360	R01071,R03655	RC00055,RC00523,RC02819,RC03200	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
SRR25158380_k127_258980_2	1128421.JAGA01000001_gene2399	3.769e-159	509.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
SRR25158380_k127_2596676_2	861299.J421_2044	3.99e-15	87.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2596676_3	643562.Daes_1331	1.245e-05	54.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MAK8@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PAS modulated sigma54 specific transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
SRR25158380_k127_2596676_0	861299.J421_4433	2.793e-314	988.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2596676_1	861299.J421_2105	3.417e-135	452.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	2|Bacteria	MU	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
SRR25158380_k127_2602261_3	35754.JNYJ01000001_gene7129	5.037e-12	70.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria,4DEWE@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158380_k127_2602261_0	861299.J421_1886	7.628e-139	452.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
SRR25158380_k127_2602261_1	670292.JH26_11815	3.892e-118	406.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_2602261_2	420324.KI911999_gene8063	1.487e-47	188.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2U77A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2602261_4	177437.HRM2_45150	3.348e-06	60.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2MJ8W@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158380_k127_2610278_3	485916.Dtox_1182	9.947e-17	81.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158380_k127_2610278_0	1379270.AUXF01000006_gene256	1.22e-159	512.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_2610278_1	1379270.AUXF01000006_gene257	2.942e-82	298.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158380_k127_2610278_2	861299.J421_3265	3.283e-78	264.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_2617473_3	861299.J421_0421	3.127e-22	111.0	COG2308@1|root,COG2308@2|Bacteria,1ZT4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158380_k127_2617473_0	379066.GAU_2002	6.314e-292	915.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
SRR25158380_k127_2617473_2	861299.J421_2345	1.029e-58	220.0	COG1597@1|root,COG1597@2|Bacteria,1ZVAI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158380_k127_2617473_1	204669.Acid345_0678	2.951e-68	245.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	yagE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158380_k127_2625988_1	861299.J421_6371	4.8e-92	309.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6371|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_2625988_0	330214.NIDE3493	0.0	1638.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	acrB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_2625988_2	861299.J421_0676	1.574e-30	123.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
SRR25158380_k127_2639992_10	1121946.AUAX01000033_gene5697	2.306e-20	93.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4DCUW@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158380_k127_2639992_1	861299.J421_1774	1.098e-108	363.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	2|Bacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158380_k127_2639992_2	861299.J421_1775	4.831e-97	344.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158380_k127_2639992_3	861299.J421_1776	2.408e-94	329.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_2639992_0	861299.J421_1777	1.993e-116	382.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_2639992_4	861299.J421_1778	5.912e-70	261.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993,ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_2639992_5	861299.J421_1779	4.95e-68	255.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_2639992_9	861299.J421_1780	5.152e-44	168.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
SRR25158380_k127_2639992_8	1379270.AUXF01000007_gene1063	2.527e-50	198.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158380_k127_2639992_6	1379270.AUXF01000007_gene1064	9.845e-65	236.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158380_k127_2639992_7	279714.FuraDRAFT_1164	2.911e-62	218.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VRJ0@28216|Betaproteobacteria,2KT22@206351|Neisseriales	206351|Neisseriales	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158380_k127_2655987_1	861299.J421_3321	3.917e-50	195.0	COG0194@1|root,COG0194@2|Bacteria,1ZTV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158380_k127_2655987_0	379066.GAU_1690	8.426e-62	223.0	COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158380_k127_2667836_6	1379270.AUXF01000004_gene3005	1.996e-67	233.0	COG0180@1|root,COG0180@2|Bacteria,1ZT3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158380_k127_2667836_3	861299.J421_2798	2.011e-76	265.0	COG0483@1|root,COG0483@2|Bacteria,1ZTQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158380_k127_2667836_1	861299.J421_2796	3.116e-99	340.0	COG0024@1|root,COG0024@2|Bacteria,1ZTC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158380_k127_2667836_8	379066.GAU_0894	4.204e-50	185.0	COG0563@1|root,COG0563@2|Bacteria,1ZTHC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
SRR25158380_k127_2667836_0	1379270.AUXF01000004_gene3012	4.022e-158	509.0	COG0201@1|root,COG0201@2|Bacteria,1ZSYZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158380_k127_2667836_10	83406.HDN1F_03840	1.084e-38	149.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158380_k127_2667836_14	861299.J421_2792	1.637e-13	74.0	COG1841@1|root,COG1841@2|Bacteria,1ZU4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L30p/L7e	-	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158380_k127_2667836_2	379066.GAU_0890	1.591e-76	269.0	COG0098@1|root,COG0098@2|Bacteria,1ZTHD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158380_k127_2667836_12	269800.Tfu_2630	1.388e-30	127.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4EJ8X@85012|Streptosporangiales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158380_k127_2667836_5	861299.J421_2789	1.643e-68	241.0	COG0097@1|root,COG0097@2|Bacteria,1ZTJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158380_k127_2667836_9	877414.ATWA01000001_gene866	1.512e-42	160.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,2696T@186813|unclassified Clostridiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158380_k127_2667836_13	700015.Corgl_1317	4.465e-22	97.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CWG8@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158380_k127_2667836_4	861299.J421_2786	1.259e-74	262.0	COG0094@1|root,COG0094@2|Bacteria,1ZSTZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158380_k127_2667836_11	379066.GAU_0884	6.05e-35	137.0	COG0198@1|root,COG0198@2|Bacteria,1ZTRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158380_k127_2667836_7	861299.J421_2784	3.042e-57	200.0	COG0093@1|root,COG0093@2|Bacteria,1ZTPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158380_k127_2678986_0	448385.sce0363	7.948e-94	323.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158380_k127_2678986_2	1192868.CAIU01000015_gene2032	2.373e-28	123.0	COG5516@1|root,COG5516@2|Bacteria,1PXF9@1224|Proteobacteria,2VDJZ@28211|Alphaproteobacteria,43QQK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158380_k127_2678986_1	2002.JOEQ01000010_gene6272	5.333e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria,4EJ1Z@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158380_k127_2721356_2	767434.Fraau_1464	6.264e-35	139.0	COG4260@1|root,COG4260@2|Bacteria,1PB6V@1224|Proteobacteria,1SURY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	virion core protein, lumpy skin disease virus	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2721356_0	861299.J421_1394	5.936e-77	283.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_2721356_1	251221.35213668	1.426e-63	229.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_2726526_1	1131269.AQVV01000002_gene1254	6.914e-86	307.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
SRR25158380_k127_2726526_0	1123508.JH636440_gene2608	1.029e-95	333.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158380_k127_2730686_0	290397.Adeh_2709	1.688e-192	629.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,42NE9@68525|delta/epsilon subdivisions,2WKU2@28221|Deltaproteobacteria,2YYXU@29|Myxococcales	28221|Deltaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158380_k127_2730686_1	1123368.AUIS01000007_gene2690	1.056e-91	313.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,1RMQP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2743590_0	1379270.AUXF01000004_gene2892	6.873e-114	376.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158380_k127_2743590_1	1379270.AUXF01000006_gene275	2e-34	143.0	COG0392@1|root,COG0392@2|Bacteria,1ZTX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158380_k127_2743590_2	358823.DF19_32255	6.549e-20	97.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2746054_2	945713.IALB_0512	8.393e-93	312.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
SRR25158380_k127_2746054_1	861299.J421_1277	6.124e-110	363.0	COG4294@1|root,COG4294@2|Bacteria	2|Bacteria	L	response to UV	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
SRR25158380_k127_2746054_4	1123073.KB899241_gene1963	5.592e-06	57.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LRR_5,Laminin_G_3,PKD
SRR25158380_k127_2746054_0	1123060.JONP01000021_gene3757	5.675e-151	491.0	COG2141@1|root,COG2141@2|Bacteria,1MUTJ@1224|Proteobacteria,2TTZI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_2746054_3	861299.J421_5978	2.436e-32	128.0	COG1940@1|root,COG1940@2|Bacteria,1ZSZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
SRR25158380_k127_2752621_3	861299.J421_3250	1.746e-52	194.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158380_k127_2752621_0	861299.J421_3251	2.723e-121	414.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
SRR25158380_k127_2752621_6	861299.J421_3252	4.714e-30	137.0	2F01D@1|root,33T57@2|Bacteria,1ZTGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2752621_7	861299.J421_3253	1.847e-25	121.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
SRR25158380_k127_2752621_1	861299.J421_3254	1.591e-109	368.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR25158380_k127_2752621_5	379066.GAU_1622	6.719e-44	172.0	COG1778@1|root,COG1778@2|Bacteria,1ZTTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
SRR25158380_k127_2752621_2	1379270.AUXF01000006_gene266	2.298e-91	311.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158380_k127_2752621_4	379066.GAU_1624	4.171e-50	181.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158380_k127_2755715_0	861299.J421_3954	6.312e-33	138.0	2C0MY@1|root,30KW5@2|Bacteria,1ZTVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2755715_1	351607.Acel_0165	1.458e-31	139.0	COG2199@1|root,COG2203@1|root,COG5000@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,2IA4H@201174|Actinobacteria	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HAMP
SRR25158380_k127_2756244_1	497965.Cyan7822_5426	1.552e-89	313.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	F5_F8_type_C,Metallophos
SRR25158380_k127_2756244_2	1077972.ARGLB_116_00480	1.666e-19	102.0	COG1409@1|root,COG3511@1|root,COG1409@2|Bacteria,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRR25158380_k127_2756244_0	1123368.AUIS01000044_gene15	1.974e-117	384.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158380_k127_2763288_0	404589.Anae109_3605	8.785e-147	472.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2763288_2	1379698.RBG1_1C00001G1774	3.469e-36	156.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158380_k127_2763288_1	927658.AJUM01000011_gene1317	1.228e-59	218.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,3XJ05@558415|Marinilabiliaceae	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SRR25158380_k127_276509_0	861299.J421_1236	6.554e-169	546.0	COG0488@1|root,COG0488@2|Bacteria,1ZSV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158380_k127_276509_2	861299.J421_1222	5.12e-40	153.0	COG1393@1|root,COG1393@2|Bacteria,1ZTUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
SRR25158380_k127_276509_4	1123226.KB899294_gene516	0.0003906	52.0	COG2304@1|root,COG2304@2|Bacteria,1V01Q@1239|Firmicutes,4HE4F@91061|Bacilli,26TQZ@186822|Paenibacillaceae	91061|Bacilli	S	Von Willebrand factor	vWFA2	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SRR25158380_k127_276509_1	713587.THITH_05550	2.007e-43	182.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1WXXC@135613|Chromatiales	135613|Chromatiales	D	Capsular exopolysaccharide family	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SRR25158380_k127_276509_3	604331.AUHY01000007_gene725	5.105e-25	109.0	COG0399@1|root,COG0399@2|Bacteria,1WJBP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158380_k127_2778013_2	1247963.JPHU01000015_gene1107	3.815e-61	214.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158380_k127_2778013_1	215803.DB30_7393	2.157e-96	325.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,2Z04D@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SRR25158380_k127_2778013_0	1278073.MYSTI_01667	2.274e-107	358.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SRR25158380_k127_2780034_0	861299.J421_3665	1.4e-244	767.0	COG1164@1|root,COG1164@2|Bacteria,1ZTDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158380_k127_2780034_2	1123229.AUBC01000001_gene1557	3.003e-22	107.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,3JZIK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158380_k127_2780034_1	861299.J421_1911	9.147e-31	124.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158380_k127_2780034_3	644548.SCNU_06680	7.002e-05	48.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,4GCXB@85026|Gordoniaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Lpp-LpqN,Pkinase
SRR25158380_k127_2780554_0	861299.J421_6152	4.858e-96	327.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRR25158380_k127_2780554_1	1101190.ARWB01000001_gene2809	1.956e-69	256.0	COG0784@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
SRR25158380_k127_278458_4	1191523.MROS_2640	7.586e-78	266.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iECH74115_1262.ECH74115_5157,iECSP_1301.ECSP_4770,iECs_1301.ECs4664,iG2583_1286.G2583_4518,iZ_1308.Z5219	PBP_like_2
SRR25158380_k127_278458_0	204669.Acid345_2974	1.169e-99	335.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158380_k127_278458_3	316067.Geob_2010	1.289e-84	301.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158380_k127_278458_2	316067.Geob_2009	2.797e-97	325.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,43U4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158380_k127_278458_1	562970.Btus_2532	1.195e-97	339.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,277YK@186823|Alicyclobacillaceae	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158380_k127_278458_5	379066.GAU_2370	7.071e-18	87.0	COG0704@1|root,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158380_k127_2788160_2	379066.GAU_0485	2.217e-60	218.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SRR25158380_k127_2788160_1	1003195.SCAT_3840	2.918e-72	256.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158380_k127_2788160_0	861299.J421_2396	0.0	1190.0	COG0188@1|root,COG0188@2|Bacteria,1ZTFF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158380_k127_2795996_2	1269813.ATUL01000022_gene793	1.351e-05	53.0	COG2199@1|root,COG3706@2|Bacteria,1RAKG@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
SRR25158380_k127_2795996_0	1379270.AUXF01000006_gene133	4.523e-155	497.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158380_k127_2795996_1	1111479.AXAR01000001_gene265	2.079e-07	59.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158380_k127_2822017_0	861299.J421_2356	4.46e-166	533.0	COG0480@1|root,COG0480@2|Bacteria,1ZTFA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158380_k127_2822017_5	1185876.BN8_06492	2.07e-07	60.0	COG5492@1|root,COG5492@2|Bacteria,4PPFX@976|Bacteroidetes,47YMG@768503|Cytophagia	976|Bacteroidetes	N	ZU5 domain	-	-	-	-	-	-	-	-	-	-	-	-	ZU5
SRR25158380_k127_2822017_3	381666.H16_A3595	1.99e-42	158.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,1KDIQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
SRR25158380_k127_2822017_6	1121946.AUAX01000030_gene1271	4.398e-06	58.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria,4DBGB@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_31,TPR_12,TPR_4
SRR25158380_k127_2822017_1	861299.J421_0829	3.094e-110	381.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GAF,HTH_8,Sigma54_activat
SRR25158380_k127_2822017_2	861299.J421_2683	1.141e-73	265.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158380_k127_2826288_0	485916.Dtox_4318	5.012e-103	341.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,264Q7@186807|Peptococcaceae	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_2826288_1	861299.J421_6309	1.689e-66	244.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6309|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_2833408_3	861299.J421_3559	6.976e-06	50.0	COG1214@1|root,COG1214@2|Bacteria,1ZU16@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158380_k127_2833408_1	1379270.AUXF01000006_gene10	3.525e-24	108.0	COG0454@1|root,COG0456@2|Bacteria,1ZU09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158380_k127_2833408_0	861299.J421_3557	1.975e-55	203.0	COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158380_k127_2833408_2	1485544.JQKP01000002_gene1573	1.302e-11	77.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,44VKI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158380_k127_2837278_3	216594.MMAR_2069	2.163e-35	141.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,236TQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	phosphoribosyl transferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158380_k127_2837278_1	710421.Mycch_2929	6.445e-110	376.0	COG0433@1|root,COG0561@1|root,COG0433@2|Bacteria,COG0561@2|Bacteria,2IDR0@201174|Actinobacteria,237AJ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,Hydrolase_3
SRR25158380_k127_2837278_0	404589.Anae109_3637	5.178e-160	520.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2YY4H@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158380_k127_2837278_2	1318628.MARLIPOL_02275	5.884e-38	157.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,466X6@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Signal transduction histidine kinase	cpxA	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158380_k127_2838004_2	1379270.AUXF01000003_gene3738	1.779e-55	202.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2838004_1	1122182.KB903813_gene2669	5.183e-80	279.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
SRR25158380_k127_2838004_0	1379270.AUXF01000001_gene2028	8.013e-126	420.0	COG0623@1|root,COG0623@2|Bacteria,1ZTGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_2838004_3	1192034.CAP_1263	2.374e-34	148.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,42SEY@68525|delta/epsilon subdivisions,2WPN4@28221|Deltaproteobacteria,2YV2J@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158380_k127_2838004_4	1379270.AUXF01000003_gene3643	5.969e-14	82.0	COG1028@1|root,COG1028@2|Bacteria,1ZT7P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_2842855_0	1128421.JAGA01000002_gene1536	7.944e-204	644.0	COG0243@1|root,COG0243@2|Bacteria,2NQFR@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158380_k127_2842855_1	1382356.JQMP01000001_gene1250	1.152e-60	214.0	COG0243@1|root,COG0243@2|Bacteria,2G62W@200795|Chloroflexi,27Z11@189775|Thermomicrobia	189775|Thermomicrobia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRR25158380_k127_2842855_2	861299.J421_6107	5.347e-37	144.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158380_k127_2845148_0	1379270.AUXF01000006_gene184	5.329e-220	689.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158380_k127_2845148_2	861299.J421_3347	5.96e-63	226.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158380_k127_2845148_4	671143.DAMO_0482	1.074e-33	139.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
SRR25158380_k127_2845148_3	224324.aq_199	2.924e-60	226.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	yocB	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
SRR25158380_k127_2845148_1	861299.J421_3349	2.654e-70	242.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158380_k127_2861304_2	861299.J421_4396	1.225e-59	210.0	arCOG09511@1|root,2Z9DH@2|Bacteria	2|Bacteria	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
SRR25158380_k127_2861304_0	1313301.AUGC01000009_gene1029	2.704e-185	593.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158380_k127_2861304_1	1122137.AQXF01000007_gene3610	1.473e-70	245.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,2TUK8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158380_k127_286667_4	861299.J421_2978	3.05e-19	98.0	COG1729@1|root,COG1729@2|Bacteria,1ZTBJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	-
SRR25158380_k127_286667_1	861299.J421_2979	2.692e-161	526.0	2CD20@1|root,2Z7SQ@2|Bacteria,1ZTFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_286667_0	861299.J421_2981	6.154e-275	871.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
SRR25158380_k127_286667_3	926569.ANT_13710	2.94e-70	250.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158380_k127_286667_2	861299.J421_3701	1.576e-127	426.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_286667_6	861299.J421_2984	2.019e-14	85.0	2FFNT@1|root,347K5@2|Bacteria,1ZTY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_286667_7	379066.GAU_0290	1.84e-05	48.0	2F3IF@1|root,33WC0@2|Bacteria,1ZTPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2870357_2	1122622.ATWJ01000002_gene800	9.83e-63	239.0	COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158380_k127_2870357_0	1379270.AUXF01000002_gene1345	7.029e-76	278.0	COG0412@1|root,COG0515@1|root,COG1262@1|root,COG0412@2|Bacteria,COG0515@2|Bacteria,COG1262@2|Bacteria,1ZUNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2870357_4	1112212.JH584235_gene1193	3.491e-14	77.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR25158380_k127_2870357_5	1463909.KL585946_gene1702	4.796e-11	67.0	2BUTG@1|root,32Q51@2|Bacteria,2ISEW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2870357_1	1205680.CAKO01000010_gene3870	1.803e-74	261.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,2JT2A@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158380_k127_288018_1	861299.J421_0625	2.722e-21	95.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158380_k127_288018_0	861299.J421_4119	4.668e-211	666.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158380_k127_288018_2	190650.CC_2539	6.125e-05	48.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2U47T@28211|Alphaproteobacteria,2KHKD@204458|Caulobacterales	204458|Caulobacterales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRR25158380_k127_2891165_6	861299.J421_3371	5.333e-24	111.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_2891165_3	379066.GAU_1729	3.312e-72	259.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158380_k127_2891165_1	1379270.AUXF01000006_gene163	3.446e-96	329.0	COG0547@1|root,COG0547@2|Bacteria,1ZTDS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158380_k127_2891165_2	379066.GAU_1726	6.282e-80	271.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158380_k127_2891165_4	404589.Anae109_0373	8.031e-55	202.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
SRR25158380_k127_2891165_5	379066.GAU_1724	3.424e-34	144.0	COG0135@1|root,COG0135@2|Bacteria,1ZTRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158380_k127_2891165_0	379066.GAU_1723	2.275e-115	376.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2891248_0	379066.GAU_1367	1.27e-262	833.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1ZSSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
SRR25158380_k127_292717_2	452637.Oter_3291	1.911e-75	266.0	COG2220@1|root,COG2220@2|Bacteria,46UV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158380_k127_292717_3	469617.FUAG_01472	4.112e-52	190.0	COG1490@1|root,COG1490@2|Bacteria,37A5U@32066|Fusobacteria	32066|Fusobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158380_k127_292717_4	861299.J421_3871	1.429e-50	201.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158380_k127_292717_0	861299.J421_3868	5.146e-122	424.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1ZT7U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
SRR25158380_k127_292717_1	1123368.AUIS01000011_gene1175	2.467e-119	397.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,2NC2Z@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158380_k127_2943528_2	861299.J421_4225	5.808e-46	175.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
SRR25158380_k127_2943528_0	379066.GAU_0642	1.552e-97	331.0	COG0520@1|root,COG0520@2|Bacteria,1ZTDV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158380_k127_2943528_1	1122917.KB899671_gene4348	9.601e-97	330.0	COG0438@1|root,COG0438@2|Bacteria,1UZT6@1239|Firmicutes,4HFIA@91061|Bacilli,26YP5@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_2943528_3	1463841.JOIR01000004_gene6297	7.747e-09	67.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria	201174|Actinobacteria	C	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158380_k127_2975284_2	1379270.AUXF01000006_gene26	2.271e-40	156.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
SRR25158380_k127_2975284_0	379066.GAU_1932	1.291e-98	340.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158380_k127_2975284_3	1379270.AUXF01000006_gene28	2.976e-15	88.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
SRR25158380_k127_2975284_4	379066.GAU_1930	3.316e-14	75.0	COG1826@1|root,COG1826@2|Bacteria,1ZU4N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158380_k127_2975284_1	861299.J421_3538	7.461e-56	209.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
SRR25158380_k127_2991524_1	861299.J421_4449	2.412e-104	360.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_2991524_0	379066.GAU_2777	4.35e-166	533.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158380_k127_3001701_1	1379270.AUXF01000004_gene3276	2.935e-42	162.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158380_k127_3001701_0	861299.J421_2545	1.12e-138	494.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158380_k127_3001701_2	1454010.JEOE01000004_gene13	7.05e-28	127.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR25158380_k127_3001701_3	1123320.KB889682_gene2128	2.922e-11	67.0	COG0745@1|root,COG0745@2|Bacteria,2GJRR@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	afsQ1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_3020173_5	1160718.SU9_10658	6.054e-35	146.0	COG3391@1|root,COG3391@2|Bacteria,2H4SV@201174|Actinobacteria	201174|Actinobacteria	MU	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
SRR25158380_k127_3020173_1	1379270.AUXF01000002_gene1363	1.586e-176	585.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158380_k127_3020173_2	1297581.H919_04974	4.228e-142	469.0	COG0843@1|root,COG0843@2|Bacteria,1TPZC@1239|Firmicutes,4HAHT@91061|Bacilli,21VDR@150247|Anoxybacillus	91061|Bacilli	C	Cytochrome C and Quinol oxidase polypeptide I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158380_k127_3020173_4	876269.ARWA01000001_gene3703	1.811e-35	144.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2U284@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRR25158380_k127_3020173_0	330214.NIDE3745	7.091e-190	624.0	COG0474@1|root,COG0474@2|Bacteria,3J0YX@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158380_k127_3020173_3	1089550.ATTH01000001_gene2448	7.842e-112	387.0	COG0076@1|root,COG0076@2|Bacteria,4P1RE@976|Bacteroidetes,1FK0C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158380_k127_3020173_6	1140.Synpcc7942_1824	5.374e-17	87.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1H08Q@1129|Synechococcus	1117|Cyanobacteria	S	CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
SRR25158380_k127_3022256_1	861299.J421_2500	4.124e-72	261.0	COG0642@1|root,COG0642@2|Bacteria,1ZTZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_3022256_0	1379270.AUXF01000004_gene3319	4.876e-218	690.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3022256_3	65393.PCC7424_0178	7.959e-23	109.0	COG2199@1|root,COG3706@2|Bacteria,1G35Y@1117|Cyanobacteria,3KG3J@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Response_reg
SRR25158380_k127_3022256_2	379066.GAU_0585	6.694e-23	104.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158380_k127_3031938_1	378806.STAUR_0050	3.891e-72	266.0	COG2843@1|root,COG2843@2|Bacteria,1Q4SV@1224|Proteobacteria,42ZT3@68525|delta/epsilon subdivisions,2WV46@28221|Deltaproteobacteria,2YX6P@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
SRR25158380_k127_3031938_0	861299.J421_2986	1.307e-160	520.0	COG0008@1|root,COG0008@2|Bacteria,1ZSSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158380_k127_304766_4	935548.KI912159_gene1181	2.021e-112	366.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,43NKE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158380_k127_304766_0	663610.JQKO01000011_gene3316	1.131e-180	573.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,3NAW1@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	mtkA	-	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158380_k127_304766_1	159450.NH14_09545	1.67e-143	463.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1K1FH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5,6.2.1.9	ko:K01902,ko:K08692	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158380_k127_304766_3	243233.MCA1407	4.482e-126	430.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RMGZ@1236|Gammaproteobacteria,1XEC8@135618|Methylococcales	135618|Methylococcales	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158380_k127_304766_2	159450.NH14_09550	2.002e-135	442.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VIG4@28216|Betaproteobacteria,1KDBG@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Phosphoenolpyruvate carboxylase	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158380_k127_3054380_1	883.DvMF_2658	3.844e-34	133.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2M9CM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_3054380_0	886293.Sinac_4895	1.224e-224	705.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158380_k127_3055979_0	713587.THITH_07575	2.873e-163	521.0	28HY3@1|root,2Z83I@2|Bacteria,1R5P3@1224|Proteobacteria,1S1M3@1236|Gammaproteobacteria,1X028@135613|Chromatiales	135613|Chromatiales	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_3055979_1	861299.J421_5846	4.225e-76	277.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
SRR25158380_k127_3067383_0	1121015.N789_00865	0.0	1303.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	GNAT family acetyltransferase	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	ATP-grasp_5,CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158380_k127_3067383_1	1121013.P873_12395	2.785e-23	100.0	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,1X9SP@135614|Xanthomonadales	135614|Xanthomonadales	PQ	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158380_k127_3070264_1	861299.J421_2949	8.478e-33	138.0	COG0799@1|root,COG0799@2|Bacteria,1ZU0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158380_k127_3070264_0	1519464.HY22_07610	2.284e-80	289.0	COG1461@1|root,COG1461@2|Bacteria	2|Bacteria	S	glycerone kinase activity	yfhG	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2,DegV
SRR25158380_k127_3075091_0	1379270.AUXF01000001_gene2066	3.863e-71	259.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158380_k127_3075091_1	1183438.GKIL_3395	4.386e-28	128.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_3077080_2	861299.J421_2888	1.722e-67	237.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158380_k127_3077080_3	861299.J421_2889	3.006e-26	124.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158380_k127_3077080_1	861299.J421_2890	6.891e-135	444.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_3077080_0	321327.CYA_2477	1.055e-208	662.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158380_k127_3081244_4	42256.RradSPS_0204	1.047e-31	130.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158380_k127_3081244_3	84531.JMTZ01000005_gene2441	1.679e-41	163.0	COG0454@1|root,COG0456@2|Bacteria,1QB34@1224|Proteobacteria,1T6KQ@1236|Gammaproteobacteria,1X7QI@135614|Xanthomonadales	135614|Xanthomonadales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_3081244_0	383372.Rcas_0232	7.07e-131	437.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158380_k127_3081244_1	861299.J421_2448	1.552e-99	341.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,1ZTZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_3081244_5	661478.OP10G_3830	1.764e-30	126.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
SRR25158380_k127_3081244_2	379066.GAU_0538	2.855e-49	190.0	COG0596@1|root,COG0596@2|Bacteria,1ZTAV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_6
SRR25158380_k127_3082673_5	861299.J421_2565	1.513e-21	96.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158380_k127_3082673_6	105425.BBPL01000031_gene4404	8.543e-08	63.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2NFGQ@228398|Streptacidiphilus	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158380_k127_3082673_1	379066.GAU_0621	9.597e-72	254.0	COG0036@1|root,COG0036@2|Bacteria,1ZSP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158380_k127_3082673_4	379066.GAU_0620	6.345e-45	172.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_3082673_0	379066.GAU_0619	9.924e-100	337.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158380_k127_3082673_2	379066.GAU_0618	8.786e-62	228.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158380_k127_3082673_3	1254432.SCE1572_38265	9.698e-48	175.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,42T7P@68525|delta/epsilon subdivisions,2X9C4@28221|Deltaproteobacteria,2YVH5@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
SRR25158380_k127_3088476_0	861299.J421_3177	5.248e-224	717.0	COG0210@1|root,COG0210@2|Bacteria,1ZTD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158380_k127_3088476_2	756499.Desde_1418	5.585e-06	55.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,262I8@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158380_k127_3088476_1	861299.J421_3179	3.964e-61	222.0	COG0154@1|root,COG0154@2|Bacteria,1ZT24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_3103260_3	1382304.JNIL01000001_gene1967	8.676e-15	75.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,277WK@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158380_k127_3103260_0	861299.J421_2757	1.511e-134	458.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158380_k127_3103260_1	300852.55773097	4.922e-70	248.0	COG0668@1|root,COG0668@2|Bacteria,1WJII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158380_k127_3103260_2	861299.J421_2756	1.359e-53	193.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SRR25158380_k127_3135588_3	1118054.CAGW01000017_gene4309	2.86e-31	130.0	COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,26WUY@186822|Paenibacillaceae	91061|Bacilli	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
SRR25158380_k127_3135588_4	1499967.BAYZ01000117_gene3342	2.344e-08	64.0	COG0739@1|root,COG0739@2|Bacteria,2NRWS@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Peptidase_M23
SRR25158380_k127_3135588_2	1122223.KB890700_gene1966	1.227e-45	173.0	COG0073@1|root,COG0073@2|Bacteria,1WK6S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Export-related chaperone CsaA	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRR25158380_k127_3135588_1	927677.ALVU02000001_gene1596	3.767e-47	173.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158380_k127_3135588_0	861299.J421_0175	3.384e-93	316.0	COG2204@1|root,COG2204@2|Bacteria,1ZTDN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3139992_0	1379270.AUXF01000007_gene963	1.8e-52	199.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158380_k127_3144952_2	195103.CPF_2819	2.306e-90	323.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
SRR25158380_k127_3144952_1	379066.GAU_2355	2.541e-103	346.0	COG1816@1|root,COG1816@2|Bacteria,1ZSQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158380_k127_3144952_3	1379270.AUXF01000003_gene3571	6.275e-07	54.0	290N8@1|root,2ZNAK@2|Bacteria,1ZU7A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3144952_0	379066.GAU_2357	3.779e-110	386.0	COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158380_k127_3152488_0	290397.Adeh_0397	6.666e-129	419.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YUF2@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	prlC	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158380_k127_3152488_2	717605.Theco_0013	0.0003094	52.0	COG2259@1|root,COG2259@2|Bacteria,1V38Q@1239|Firmicutes,4IRNH@91061|Bacilli,26WX9@186822|Paenibacillaceae	91061|Bacilli	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158380_k127_3152488_1	479434.Sthe_2440	2.66e-72	246.0	COG1505@1|root,COG1505@2|Bacteria,2GBNH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158380_k127_3153191_0	861299.J421_3630	8.698e-254	815.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158380_k127_3153191_3	1184267.A11Q_1512	1.061e-34	140.0	COG3303@1|root,COG3303@2|Bacteria,1QY22@1224|Proteobacteria,43C9D@68525|delta/epsilon subdivisions,2MTWU@213481|Bdellovibrionales,2WQ1C@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SRR25158380_k127_3153191_2	1499967.BAYZ01000100_gene3464	4.351e-46	185.0	COG0565@1|root,COG0565@2|Bacteria,2NQ39@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.200,3.5.1.19,6.1.1.16	ko:K01883,ko:K02533,ko:K08281,ko:K15396	ko00760,ko00970,ko01100,map00760,map00970,map01100	M00359,M00360	R01268,R03650	RC00055,RC00100,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	SpoU_methylase
SRR25158380_k127_3153191_1	861299.J421_3743	2.411e-129	417.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158380_k127_3153548_3	379066.GAU_0818	9.39e-84	284.0	COG0554@1|root,COG0554@2|Bacteria,1ZTX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158380_k127_3153548_4	1122185.N792_12105	4.134e-28	123.0	2E3HM@1|root,32YG7@2|Bacteria,1NM0U@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3153548_2	404589.Anae109_2569	1.728e-93	331.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
SRR25158380_k127_3153548_5	717231.Flexsi_0048	4.267e-16	82.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158380_k127_3153548_7	290397.Adeh_1200	4.234e-07	61.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SRR25158380_k127_3153548_6	290397.Adeh_1201	3.276e-11	72.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
SRR25158380_k127_3153548_0	290397.Adeh_1202	1.458e-192	620.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SRR25158380_k127_3153548_1	404589.Anae109_2563	2.066e-102	348.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158380_k127_3170598_1	42256.RradSPS_2456	2.417e-49	182.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
SRR25158380_k127_3170598_0	861299.J421_1043	2.048e-171	552.0	COG0467@1|root,COG0467@2|Bacteria,1ZUWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158380_k127_3170598_2	1179778.PMM47T1_07991	2.018e-22	102.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SRR25158380_k127_3193045_2	1499967.BAYZ01000157_gene595	6.435e-45	175.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
SRR25158380_k127_3193045_0	794846.AJQU01000062_gene2573	7.427e-69	240.0	2E3HM@1|root,32YG7@2|Bacteria,1RFJA@1224|Proteobacteria,2U8PF@28211|Alphaproteobacteria,4BEHC@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3193045_1	365044.Pnap_2774	1.419e-52	190.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2VJ5B@28216|Betaproteobacteria,4AC0Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158380_k127_3206672_0	861299.J421_3082	1.104e-50	203.0	COG1572@1|root,COG1572@2|Bacteria,1ZSTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3206672_1	645991.Sgly_0715	3.364e-47	177.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,260RZ@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158380_k127_321542_0	240015.ACP_0267	1.36e-156	505.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158380_k127_321542_2	1144305.PMI02_00488	7.244e-13	73.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,2K9V3@204457|Sphingomonadales	204457|Sphingomonadales	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH,PBP
SRR25158380_k127_321542_1	717605.Theco_3656	8.893e-79	274.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,26V88@186822|Paenibacillaceae	91061|Bacilli	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
SRR25158380_k127_3227988_2	861299.J421_1517	5.633e-61	221.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3227988_1	102129.Lepto7375DRAFT_2070	3.282e-98	339.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,1H7VM@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158380_k127_3227988_0	1121405.dsmv_0355	1.116e-187	598.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MHQI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158380_k127_3234497_0	243233.MCA0142	3.107e-96	325.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158380_k127_3234497_1	1379270.AUXF01000006_gene312	2.475e-95	323.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158380_k127_3234497_2	861299.J421_3210	6.907e-25	114.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SRR25158380_k127_3239160_2	379066.GAU_2858	3.822e-32	145.0	COG0578@1|root,COG0578@2|Bacteria,1ZT6P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158380_k127_3239160_3	1123504.JQKD01000020_gene5637	1.318e-28	121.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2WGK0@28216|Betaproteobacteria,4ADYH@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158380_k127_3239160_0	379066.GAU_2857	5.641e-166	532.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_3239160_1	1379270.AUXF01000001_gene2467	2.959e-165	538.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1ZT1A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158380_k127_3246062_1	489825.LYNGBM3L_22490	8.785e-75	264.0	COG0578@1|root,COG0578@2|Bacteria,1G1T3@1117|Cyanobacteria,1H86N@1150|Oscillatoriales	1117|Cyanobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158380_k127_3246062_2	472759.Nhal_3328	4.026e-66	239.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXFS@135613|Chromatiales	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_3246062_0	766499.C357_22955	5.848e-82	284.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2TTR9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_3246062_3	379066.GAU_0585	1.463e-42	157.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158380_k127_3250966_3	861299.J421_3214	3.753e-13	70.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158380_k127_3250966_2	379066.GAU_1582	1.131e-43	167.0	COG3880@1|root,COG3880@2|Bacteria,1ZTPQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
SRR25158380_k127_3250966_1	1379270.AUXF01000006_gene305	7.01e-133	435.0	COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
SRR25158380_k127_3250966_0	861299.J421_3217	2.897e-137	439.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158380_k127_3258424_3	379066.GAU_0737	3.55e-05	46.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158380_k127_3258424_0	1379270.AUXF01000004_gene3142	4.721e-139	450.0	COG0825@1|root,COG0825@2|Bacteria,1ZSW6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158380_k127_3258424_1	861299.J421_2654	8.482e-99	334.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR25158380_k127_3258424_2	379066.GAU_0734	3.969e-74	258.0	COG0143@1|root,COG0143@2|Bacteria,1ZTDB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (M)	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158380_k127_3260483_0	379066.GAU_2797	4.961e-208	654.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158380_k127_3264331_2	204669.Acid345_2164	1.822e-19	91.0	COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria,2JJGU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_3264331_0	379066.GAU_0627	1.11e-138	451.0	COG0343@1|root,COG0343@2|Bacteria,1ZSRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158380_k127_3264331_3	1123503.KB908058_gene1016	8.764e-12	70.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2KHAM@204458|Caulobacterales	204458|Caulobacterales	U	Preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158380_k127_3264331_1	379066.GAU_0625	1.332e-29	126.0	COG0242@1|root,COG0242@2|Bacteria,1ZTPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158380_k127_3265171_0	861299.J421_2362	2.974e-101	347.0	COG0277@1|root,COG0277@2|Bacteria,1ZTB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158380_k127_3265171_1	1157490.EL26_01200	2.677e-31	133.0	COG1852@1|root,COG1852@2|Bacteria,1V1B5@1239|Firmicutes,4HUDI@91061|Bacilli,279H3@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
SRR25158380_k127_3265171_3	697282.Mettu_0887	3.298e-07	60.0	COG4244@1|root,COG4244@2|Bacteria,1NB74@1224|Proteobacteria,1SI9C@1236|Gammaproteobacteria,1XF4F@135618|Methylococcales	135618|Methylococcales	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158380_k127_3265171_2	861299.J421_2367	7.17e-20	97.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3266637_3	861299.J421_1927	1.288e-07	54.0	COG0845@1|root,COG0845@2|Bacteria,1ZUDM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR25158380_k127_3266637_0	861299.J421_1928	0.0	1323.0	COG0841@1|root,COG0841@2|Bacteria,1ZUMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MMPL family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158380_k127_3266637_1	204669.Acid345_4600	1.951e-98	339.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_3266637_2	1379270.AUXF01000002_gene1829	7.069e-12	66.0	COG3336@1|root,COG3336@2|Bacteria,1ZT56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158380_k127_3268748_0	234267.Acid_5036	1.972e-91	329.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
SRR25158380_k127_3268748_1	1267534.KB906755_gene4047	1.546e-46	192.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158380_k127_3268894_1	379066.GAU_1166	1.583e-50	185.0	COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3268894_3	1382356.JQMP01000004_gene448	4.599e-28	129.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,27YFE@189775|Thermomicrobia	189775|Thermomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158380_k127_3268894_0	861299.J421_2914	1.419e-77	269.0	COG1606@1|root,COG1606@2|Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
SRR25158380_k127_3268894_2	861299.J421_3990	1.281e-34	137.0	COG1186@1|root,COG1186@2|Bacteria,1ZTZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158380_k127_3273296_1	479434.Sthe_3148	4.311e-101	346.0	COG0428@1|root,COG0428@2|Bacteria,2G9IR@200795|Chloroflexi	200795|Chloroflexi	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3273296_0	266117.Rxyl_0083	1.08e-123	409.0	COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_3273296_2	383372.Rcas_3322	1.722e-10	64.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158380_k127_3290513_6	309807.SRU_0340	9.622e-26	114.0	COG1183@1|root,COG1183@2|Bacteria,4PEY9@976|Bacteroidetes,1FJUP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	phosphatidylcholine synthase activity	-	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_3290513_3	652103.Rpdx1_0234	5.559e-68	236.0	COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,2U0WW@28211|Alphaproteobacteria,3JZ3I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158380_k127_3290513_5	234267.Acid_1797	1.241e-38	157.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
SRR25158380_k127_3290513_2	469383.Cwoe_0461	2.425e-96	338.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4CQZX@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158380_k127_3290513_0	1459636.NTE_01340	3.289e-167	532.0	COG0350@1|root,arCOG02724@2157|Archaea	2157|Archaea	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,DUF1938
SRR25158380_k127_3290513_1	84531.JMTZ01000001_gene2230	3.433e-119	399.0	COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,1RNKY@1236|Gammaproteobacteria,1X4MJ@135614|Xanthomonadales	135614|Xanthomonadales	S	Oxidoreductase	ydgJ	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_3290513_4	1089549.AZUQ01000001_gene511	1.32e-40	153.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158380_k127_3291969_3	861299.J421_3233	2.702e-86	305.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158380_k127_3291969_2	861299.J421_2550	3.047e-123	409.0	COG0266@1|root,COG0266@2|Bacteria,1ZUR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158380_k127_3291969_0	1379270.AUXF01000006_gene290	1.624e-217	690.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158380_k127_3291969_1	1267535.KB906767_gene597	9.906e-146	474.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158380_k127_3295846_5	518766.Rmar_0752	1.013e-13	71.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1FJ15@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_3295846_1	861299.J421_3004	1.187e-154	497.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_3295846_2	379066.GAU_1294	2.487e-48	186.0	COG0698@1|root,COG0698@2|Bacteria,1ZUTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158380_k127_3295846_0	1430331.EP10_10230	3.304e-170	545.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1WG2H@129337|Geobacillus	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158380_k127_3295846_3	861299.J421_3006	7.001e-37	145.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3295846_4	861299.J421_3007	2.802e-28	119.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3297559_0	861299.J421_2090	9.239e-160	505.0	COG0719@1|root,COG0719@2|Bacteria,1ZSMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158380_k127_3297559_1	861299.J421_2089	6.113e-121	393.0	COG0396@1|root,COG0396@2|Bacteria,1ZSRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158380_k127_3297559_2	861299.J421_2088	2.126e-68	248.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158380_k127_3299059_2	1128421.JAGA01000002_gene11	1.591e-29	122.0	COG4277@1|root,COG4277@2|Bacteria	2|Bacteria	-	-	MA20_15955	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	HHH_3,Radical_SAM
SRR25158380_k127_3299059_0	234267.Acid_3206	3.788e-88	317.0	COG0784@1|root,COG3852@1|root,COG0784@2|Bacteria,COG3852@2|Bacteria,3Y6AK@57723|Acidobacteria	57723|Acidobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158380_k127_3299059_1	1464048.JNZS01000010_gene5191	2.746e-75	263.0	COG5637@1|root,COG5637@2|Bacteria,2GP5P@201174|Actinobacteria	201174|Actinobacteria	S	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158380_k127_3304701_1	1191523.MROS_0965	1.029e-30	133.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158380_k127_3304701_0	1499967.BAYZ01000057_gene4683	3.862e-52	206.0	COG0210@1|root,COG0210@2|Bacteria,2NQHW@2323|unclassified Bacteria	2|Bacteria	L	3' exoribonuclease, RNase T-like	-	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RNase_T,UvrD-helicase,UvrD_C
SRR25158380_k127_3323952_1	861299.J421_4311	2.196e-48	193.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
SRR25158380_k127_3323952_0	404589.Anae109_1190	1.67e-200	648.0	COG1012@1|root,COG1012@2|Bacteria,1R528@1224|Proteobacteria,433YD@68525|delta/epsilon subdivisions,2X42A@28221|Deltaproteobacteria,2YY1Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.5	ko:K00129	ko00010,ko00340,ko00350,ko00360,ko00410,ko00980,ko00982,ko01100,ko01110,ko01120,ko05204,map00010,map00340,map00350,map00360,map00410,map00980,map00982,map01100,map01110,map01120,map05204	-	R00711,R00904,R02536,R02537,R02695,R02697,R03300,R03302,R04882,R04883,R04888,R04889,R04891,R04892,R04996,R07104,R08282,R08283,R08307	RC00047,RC00080,RC00242,RC01735	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158380_k127_3324153_1	292564.Cyagr_0646	1.529e-35	147.0	COG0514@1|root,COG0514@2|Bacteria,1G1Y1@1117|Cyanobacteria,22SHJ@167375|Cyanobium	1117|Cyanobacteria	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158380_k127_3324153_0	1254432.SCE1572_02795	1.191e-108	362.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158380_k127_3333789_3	1121382.JQKG01000033_gene3168	1.109e-63	228.0	COG0415@1|root,COG0415@2|Bacteria,1WM2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
SRR25158380_k127_3333789_1	452637.Oter_3088	1.91e-72	256.0	COG3647@1|root,COG3647@2|Bacteria,46W76@74201|Verrucomicrobia,3K781@414999|Opitutae	414999|Opitutae	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR25158380_k127_3333789_0	861299.J421_4331	6.112e-110	365.0	COG1234@1|root,COG1234@2|Bacteria,1ZTG7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158380_k127_3333789_5	688270.Celal_3111	1.626e-19	100.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia,1F8BK@104264|Cellulophaga	976|Bacteroidetes	Q	COGs COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158380_k127_3333789_2	565034.BHWA1_00200	9.852e-70	244.0	COG1127@1|root,COG1127@2|Bacteria,2J7DZ@203691|Spirochaetes	203691|Spirochaetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158380_k127_3333789_4	1379270.AUXF01000001_gene2818	1.122e-30	125.0	COG0767@1|root,COG0767@2|Bacteria,1ZSUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158380_k127_3343228_1	379066.GAU_2889	3.016e-46	170.0	COG2060@1|root,COG2060@2|Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iSB619.SA_RS00490	KdpA
SRR25158380_k127_3343228_0	1379698.RBG1_1C00001G0290	5.558e-136	462.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
SRR25158380_k127_3343228_2	204669.Acid345_2044	2.042e-25	110.0	COG0662@1|root,COG0662@2|Bacteria,3Y8RS@57723|Acidobacteria,2JNY9@204432|Acidobacteriia	204432|Acidobacteriia	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_3343228_3	404589.Anae109_4139	2.062e-19	89.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158380_k127_3345907_2	105559.Nwat_2843	5.034e-13	71.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,1WYZU@135613|Chromatiales	135613|Chromatiales	S	PFAM Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158380_k127_3345907_0	387093.SUN_1532	6.303e-78	273.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR25158380_k127_3345907_1	118161.KB235922_gene223	1.611e-66	232.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3VJFW@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR25158380_k127_335975_4	861299.J421_2896	3.234e-10	61.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158380_k127_335975_1	861299.J421_2892	3.494e-113	377.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158380_k127_335975_0	861299.J421_2891	4.475e-125	430.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158380_k127_335975_3	357808.RoseRS_3547	5.052e-28	117.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi,375XQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158380_k127_335975_2	118163.Ple7327_2011	1.271e-44	168.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,3VJ01@52604|Pleurocapsales	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158380_k127_3363434_3	290397.Adeh_3989	1.071e-57	228.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,42RD4@68525|delta/epsilon subdivisions,2WN11@28221|Deltaproteobacteria,2YU83@29|Myxococcales	28221|Deltaproteobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_3363434_0	251221.35211608	1.645e-154	496.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158380_k127_3363434_2	379066.GAU_2861	1.769e-94	317.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158380_k127_3363434_4	379066.GAU_2867	1.964e-26	114.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3363434_1	404589.Anae109_1625	8.393e-153	499.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_3363434_5	1515613.HQ37_08195	1.331e-24	120.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia,22W87@171551|Porphyromonadaceae	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRR25158380_k127_337556_2	861299.J421_3301	1.149e-45	167.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158380_k127_337556_1	379066.GAU_1669	8.536e-64	229.0	2CAZH@1|root,2Z7RU@2|Bacteria,1ZTQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
SRR25158380_k127_337556_0	326427.Cagg_1577	0.0	1076.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158380_k127_337556_3	1089549.AZUQ01000001_gene2631	7.846e-17	92.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4EXYY@85014|Glycomycetales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
SRR25158380_k127_3381722_3	861299.J421_3658	8.99e-44	177.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_3658|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_3381722_2	861299.J421_4438	6.431e-52	191.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158380_k127_3381722_1	861299.J421_3660	8.398e-78	278.0	2E98K@1|root,333GZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3381722_5	379066.GAU_2601	0.0006882	51.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3381722_6	1379270.AUXF01000001_gene2791	0.0009151	50.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3381722_4	379066.GAU_1049	3.198e-06	55.0	2EB13@1|root,3351Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3381722_0	861299.J421_2624	6e-90	306.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158380_k127_3403805_0	861299.J421_1695	3.608e-104	357.0	COG0457@1|root,COG0457@2|Bacteria,1ZV58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3403805_8	512565.AMIS_31010	4.125e-19	94.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRR25158380_k127_3403805_7	118173.KB235914_gene1036	8.841e-25	117.0	COG0454@1|root,COG0456@2|Bacteria,1G7IH@1117|Cyanobacteria,1HCII@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_3403805_3	861299.J421_1965	4.613e-67	245.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158380_k127_3403805_1	1123256.KB907925_gene1355	1.547e-73	253.0	COG0740@1|root,COG0740@2|Bacteria,1RBNX@1224|Proteobacteria,1S4TV@1236|Gammaproteobacteria,1X6ND@135614|Xanthomonadales	135614|Xanthomonadales	OU	Clp protease	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
SRR25158380_k127_3403805_2	1123368.AUIS01000004_gene272	6.43e-69	240.0	COG3663@1|root,COG3663@2|Bacteria,1RAVZ@1224|Proteobacteria,1S2GN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158380_k127_3403805_9	32042.PstZobell_13361	5.534e-11	73.0	2983E@1|root,2ZV9D@2|Bacteria,1QTCK@1224|Proteobacteria,1SV2J@1236|Gammaproteobacteria,1Z3GX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3403805_5	861299.J421_0548	2.594e-48	179.0	COG5483@1|root,COG5483@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF488	MA20_09495	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158380_k127_3403805_6	1356852.N008_16470	1.063e-47	181.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_3403805_4	1248916.ANFY01000010_gene419	7.497e-49	178.0	COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria,2UCCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
SRR25158380_k127_3419084_2	875328.JDM601_1011	3.43e-19	96.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,23355@1762|Mycobacteriaceae	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158380_k127_3419084_1	1379270.AUXF01000001_gene2675	4.95e-36	142.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158380_k127_3419084_0	861299.J421_4453	1.879e-77	261.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1ZTC2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158380_k127_3429047_4	379066.GAU_1519	2.27e-12	70.0	COG0268@1|root,COG0268@2|Bacteria,1ZU6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158380_k127_3429047_1	861299.J421_3146	1.505e-62	223.0	COG1994@1|root,COG1994@2|Bacteria,1ZTIB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158380_k127_3429047_3	1382304.JNIL01000001_gene339	2.371e-32	143.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,279W3@186823|Alicyclobacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158380_k127_3429047_0	379066.GAU_1522	1.775e-63	227.0	COG1386@1|root,COG1386@2|Bacteria,1ZTIA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158380_k127_3429047_2	861299.J421_3149	2.904e-59	221.0	COG1187@1|root,COG1187@2|Bacteria,1ZT5B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158380_k127_3440362_0	379066.GAU_0638	8.406e-194	619.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
SRR25158380_k127_3440362_1	1379270.AUXF01000004_gene3243	2.545e-139	484.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158380_k127_3440362_2	237368.SCABRO_02904	7.28e-26	119.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	ykvP	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_2,LysM
SRR25158380_k127_3440362_3	1121272.KB903289_gene4297	4.519e-05	48.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DAQI@85008|Micromonosporales	201174|Actinobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_3444939_3	861299.J421_3685	2.641e-18	88.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158380_k127_3444939_0	1123368.AUIS01000044_gene15	8.128e-92	331.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158380_k127_3444939_1	404589.Anae109_3606	2.708e-28	120.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
SRR25158380_k127_3444939_2	404589.Anae109_3605	9.178e-24	102.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_3463446_2	666685.R2APBS1_2039	1.035e-25	114.0	COG0845@1|root,COG0845@2|Bacteria,1R6JG@1224|Proteobacteria,1SEA3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3463446_0	666685.R2APBS1_2040	0.0	1026.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,1X3KY@135614|Xanthomonadales	135614|Xanthomonadales	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158380_k127_3463446_1	1047013.AQSP01000105_gene1436	2.334e-56	224.0	COG2421@1|root,COG2421@2|Bacteria,2NR72@2323|unclassified Bacteria	2|Bacteria	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
SRR25158380_k127_3469930_3	1121939.L861_11025	8.369e-05	49.0	COG5662@1|root,COG5662@2|Bacteria,1NG37@1224|Proteobacteria,1ST5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158380_k127_3469930_0	525904.Tter_0756	5.784e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_3469930_2	861299.J421_4179	3.05e-28	122.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3469930_1	379066.GAU_2584	2.853e-37	154.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SRR25158380_k127_3478625_0	1192034.CAP_8674	1.036e-191	618.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158380_k127_3478625_4	404380.Gbem_0454	2.508e-15	77.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,43VXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3478625_3	639030.JHVA01000001_gene760	3.513e-17	88.0	2E34G@1|root,32Y4J@2|Bacteria,3Y5JB@57723|Acidobacteria,2JJW7@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3478625_2	1463825.JNXC01000029_gene475	1.163e-19	104.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4DY4W@85010|Pseudonocardiales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158380_k127_3478625_1	379066.GAU_0555	1.716e-156	514.0	COG1960@1|root,COG1960@2|Bacteria,1ZT6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_3491928_1	357808.RoseRS_2983	8.365e-154	490.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi,376YP@32061|Chloroflexia	32061|Chloroflexia	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_3491928_0	179408.Osc7112_5893	1.129e-280	872.0	COG0129@1|root,COG0129@2|Bacteria,1G0KD@1117|Cyanobacteria,1H8V6@1150|Oscillatoriales	1117|Cyanobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158380_k127_3491928_2	1234664.AMRO01000027_gene1264	7.26e-31	125.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1WE1H@129337|Geobacillus	91061|Bacilli	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU28270	Iso_dh
SRR25158380_k127_3496807_1	1123508.JH636441_gene3784	7.663e-86	290.0	COG2037@1|root,COG2037@2|Bacteria,2IX8D@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	-	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
SRR25158380_k127_3496807_2	891968.Anamo_1136	3.28e-32	142.0	COG2218@1|root,COG2218@2|Bacteria,3TC5A@508458|Synergistetes	508458|Synergistetes	C	GXGXG motif	-	-	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
SRR25158380_k127_3496807_0	1380390.JIAT01000010_gene4329	1.634e-97	329.0	COG3252@1|root,COG3252@2|Bacteria	2|Bacteria	H	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT	mch	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704	3.5.4.27	ko:K01499	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03464	RC01870	ko00000,ko00001,ko00002,ko01000	-	-	-	MCH
SRR25158380_k127_3496807_4	880070.Cycma_0841	1.459e-15	86.0	COG3224@1|root,COG3224@2|Bacteria,4NT3E@976|Bacteroidetes,47VYH@768503|Cytophagia	976|Bacteroidetes	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
SRR25158380_k127_3496807_5	1048339.KB913029_gene2200	5.978e-13	78.0	COG3224@1|root,COG3224@2|Bacteria,2GQKQ@201174|Actinobacteria,4EWKU@85013|Frankiales	201174|Actinobacteria	S	ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
SRR25158380_k127_3496807_3	1304874.JAFY01000002_gene392	2.272e-25	108.0	COG0189@1|root,COG0189@2|Bacteria,3TBW9@508458|Synergistetes	508458|Synergistetes	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158380_k127_3500941_3	316274.Haur_1580	1.591e-21	108.0	COG4430@1|root,COG4430@2|Bacteria,2G8DH@200795|Chloroflexi	200795|Chloroflexi	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158380_k127_3500941_2	1340493.JNIF01000003_gene2361	1.109e-30	129.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_3500941_4	204669.Acid345_1563	8.11e-19	94.0	2ESJ3@1|root,33K3T@2|Bacteria,3Y8Y6@57723|Acidobacteria,2JNTF@204432|Acidobacteriia	204432|Acidobacteriia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158380_k127_3500941_1	861299.J421_0746	2.005e-38	154.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158380_k127_3500941_0	469383.Cwoe_4585	2.221e-45	169.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_3505649_1	861299.J421_2390	4.432e-35	136.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_3505649_0	1379270.AUXF01000002_gene1817	2.476e-57	208.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
SRR25158380_k127_3505649_2	1122137.AQXF01000003_gene2417	1.942e-19	96.0	COG2234@1|root,COG2234@2|Bacteria,1NVWC@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_3509173_5	1380355.JNIJ01000024_gene2317	8.635e-12	67.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,2UFVS@28211|Alphaproteobacteria,3K0T0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158380_k127_3509173_2	224911.27353153	8.392e-39	148.0	COG0251@1|root,COG0251@2|Bacteria,1N35M@1224|Proteobacteria,2VF3M@28211|Alphaproteobacteria,3JY0S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158380_k127_3509173_3	906888.JCM19314_531	4.819e-38	153.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia,3HKGJ@363408|Nonlabens	976|Bacteroidetes	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_3509173_6	1123073.KB899241_gene1963	4.062e-09	66.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LRR_5,Laminin_G_3,PKD
SRR25158380_k127_3509173_1	1144275.COCOR_00104	1.252e-91	308.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_3509173_0	448385.sce6417	2.161e-109	357.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_3525771_0	861299.J421_3137	2.712e-316	979.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158380_k127_3525771_4	861299.J421_3139	1.107e-44	169.0	COG0590@1|root,COG0590@2|Bacteria,1ZTW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158380_k127_3525771_6	211165.AJLN01000084_gene1724	2.306e-17	93.0	COG0330@1|root,COG0330@2|Bacteria,1G356@1117|Cyanobacteria,1JKBK@1189|Stigonemataceae	1117|Cyanobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_3525771_1	861299.J421_0323	2.847e-109	364.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158380_k127_3525771_2	861299.J421_0823	7.632e-102	340.0	COG2514@1|root,COG2514@2|Bacteria,1ZTDT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158380_k127_3525771_3	1191523.MROS_0148	5.344e-91	313.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
SRR25158380_k127_3525771_7	1168059.KB899087_gene1061	4.876e-05	49.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158380_k127_3525771_5	1210884.HG799462_gene8895	3.558e-25	108.0	COG3852@1|root,COG3852@2|Bacteria,2J4Y6@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158380_k127_3554835_0	404589.Anae109_0064	9.527e-147	475.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_3554835_1	269799.Gmet_0814	2.2e-86	301.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_3554835_2	861299.J421_2367	7.412e-09	60.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_356874_0	861299.J421_0270	1.194e-23	115.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60
SRR25158380_k127_356874_1	1121920.AUAU01000002_gene2147	1.01e-19	92.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.133,2.5.1.62	ko:K04040,ko:K20616	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
SRR25158380_k127_3574603_5	1379270.AUXF01000005_gene456	1.082e-55	199.0	COG0577@1|root,COG0577@2|Bacteria,1ZUU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3574603_2	379066.GAU_3473	4.161e-106	361.0	COG0577@1|root,COG0577@2|Bacteria,1ZT67@142182|Gemmatimonadetes	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3574603_0	861299.J421_1415	4.328e-143	468.0	COG0577@1|root,COG0577@2|Bacteria,1ZUG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3574603_1	1379270.AUXF01000005_gene449	5.236e-139	452.0	COG0577@1|root,COG0577@2|Bacteria,1ZUCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3574603_4	861299.J421_5612	1.498e-61	224.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
SRR25158380_k127_3574603_3	1379270.AUXF01000005_gene405	3.927e-86	292.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158380_k127_3574970_1	886293.Sinac_0764	1.296e-85	294.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2J20Q@203682|Planctomycetes	203682|Planctomycetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158380_k127_3574970_3	1173027.Mic7113_3987	7.08e-48	178.0	COG2172@1|root,COG2172@2|Bacteria,1G668@1117|Cyanobacteria,1HBSH@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c
SRR25158380_k127_3574970_2	1198452.Jab_2c00360	4.984e-50	181.0	COG1366@1|root,COG1366@2|Bacteria,1RJM8@1224|Proteobacteria,2VT28@28216|Betaproteobacteria,477CH@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158380_k127_3574970_0	886293.Sinac_0761	2.42e-100	332.0	COG1366@1|root,COG1366@2|Bacteria,2J23N@203682|Planctomycetes	203682|Planctomycetes	T	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
SRR25158380_k127_3600798_0	379066.GAU_2430	5.651e-104	347.0	COG3437@1|root,COG3437@2|Bacteria,1ZSX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
SRR25158380_k127_3600798_1	861299.J421_2457	6.433e-74	263.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR25158380_k127_3606193_0	861299.J421_2109	5.037e-109	364.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158380_k127_3606193_3	1150474.JQJI01000002_gene1102	3.526e-28	117.0	COG2151@1|root,COG2151@2|Bacteria,2GDA3@200918|Thermotogae	200918|Thermotogae	S	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158380_k127_3606193_1	861299.J421_2113	2.873e-84	295.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_3606193_4	251221.35213457	7.489e-07	60.0	COG0666@1|root,COG5549@1|root,COG0666@2|Bacteria,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,Peptidase_M10
SRR25158380_k127_3606193_2	1489678.RDMS_09410	2.084e-52	203.0	COG2409@1|root,COG2409@2|Bacteria,1WJIE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2409 drug exporter of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158380_k127_3614988_4	1089550.ATTH01000002_gene52	1.553e-23	113.0	COG0457@1|root,COG4319@1|root,COG0457@2|Bacteria,COG4319@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440,SnoaL_2,SnoaL_3
SRR25158380_k127_3614988_0	316067.Geob_1654	3.294e-144	468.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,42QH0@68525|delta/epsilon subdivisions,2WJY7@28221|Deltaproteobacteria,43UNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
SRR25158380_k127_3614988_1	859657.RPSI07_2021	5.178e-129	418.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,1K08X@119060|Burkholderiaceae	28216|Betaproteobacteria	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158380_k127_3614988_2	1183438.GKIL_3877	2.145e-125	406.0	COG0555@1|root,COG0555@2|Bacteria,1FZVV@1117|Cyanobacteria	1117|Cyanobacteria	O	Sulfate ABC transporter, permease protein CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158380_k127_3614988_3	1120973.AQXL01000115_gene650	5.38e-86	287.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,4HD5R@91061|Bacilli	91061|Bacilli	P	COG1613 ABC-type sulfate transport system, periplasmic component	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRR25158380_k127_36153_5	383372.Rcas_3054	3.446e-70	240.0	COG0229@1|root,COG0229@2|Bacteria,2G78V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158380_k127_36153_7	937777.Deipe_0664	1.438e-39	153.0	COG3477@1|root,COG3477@2|Bacteria	2|Bacteria	S	response to acidic pH	yagU	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K08996	-	-	-	-	ko00000	-	-	-	DUF1440
SRR25158380_k127_36153_1	518766.Rmar_0365	4.375e-109	362.0	COG3842@1|root,COG3842@2|Bacteria,4NEFE@976|Bacteroidetes,1FJ9W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ABC transporter	potA	-	3.6.3.31	ko:K10112,ko:K11072,ko:K17324	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00299,M00491,M00602,M00605,M00606,M00607	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.35,3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158380_k127_36153_4	484019.THA_846	1.606e-78	283.0	COG0395@1|root,COG0395@2|Bacteria,2GCIV@200918|Thermotogae	200918|Thermotogae	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158380_k127_36153_2	935948.KE386495_gene1086	1.666e-82	284.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,42FWJ@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
SRR25158380_k127_36153_3	390874.Tpet_0954	6.767e-81	287.0	COG1653@1|root,COG1653@2|Bacteria,2GC1I@200918|Thermotogae	200918|Thermotogae	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
SRR25158380_k127_36153_6	1340493.JNIF01000004_gene473	3.552e-46	190.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_36153_0	1121930.AQXG01000001_gene1300	3.541e-174	571.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1IYME@117747|Sphingobacteriia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158380_k127_36153_9	309807.SRU_1157	2.538e-07	57.0	COG3391@1|root,COG3391@2|Bacteria,4PF0H@976|Bacteroidetes,1FJY5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3615742_1	379066.GAU_1107	2.217e-140	454.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158380_k127_3615742_2	861299.J421_2873	8.007e-128	430.0	COG0166@1|root,COG0166@2|Bacteria,1ZU5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158380_k127_3615742_3	1379270.AUXF01000005_gene378	6.361e-98	326.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SRR25158380_k127_3615742_0	1379270.AUXF01000005_gene377	6.513e-150	488.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158380_k127_3616786_3	404380.Gbem_3255	1.059e-05	56.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,43RZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158380_k127_3616786_1	591159.ACEZ01000013_gene6727	2.743e-84	310.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158380_k127_3616786_0	748247.AZKH_2968	3.509e-104	349.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158380_k127_3616786_2	661478.OP10G_1632	5.4e-33	133.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158380_k127_363282_0	861299.J421_3217	0.0	1018.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158380_k127_363282_1	861299.J421_3218	1.746e-211	702.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158380_k127_363282_2	1379270.AUXF01000006_gene302	3.749e-20	98.0	COG2825@1|root,COG2825@2|Bacteria,1ZU5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158380_k127_3633699_0	378806.STAUR_5485	1.326e-46	175.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,42M1Z@68525|delta/epsilon subdivisions,2WJYC@28221|Deltaproteobacteria,2YXXR@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158380_k127_3633699_3	404589.Anae109_0230	7.818e-38	154.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,42RNT@68525|delta/epsilon subdivisions,2WNHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158380_k127_3633699_2	1218074.BAXZ01000036_gene5260	2.684e-42	163.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158380_k127_3633699_1	1123256.KB907928_gene2075	6.958e-45	171.0	COG2885@1|root,COG2885@2|Bacteria,1NUID@1224|Proteobacteria,1SNFQ@1236|Gammaproteobacteria,1X6KY@135614|Xanthomonadales	135614|Xanthomonadales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158380_k127_3636311_0	861299.J421_5976	3.284e-84	294.0	COG1533@1|root,COG1533@2|Bacteria,1ZUFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_3636311_1	448385.sce6416	2.312e-60	212.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,439P5@68525|delta/epsilon subdivisions,2X50M@28221|Deltaproteobacteria,2YZXZ@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158380_k127_3636605_7	234267.Acid_6292	5.621e-11	65.0	COG3127@1|root,COG3127@2|Bacteria,3Y7ZT@57723|Acidobacteria	57723|Acidobacteria	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3636605_6	1283284.AZUK01000002_gene2785	6.971e-55	195.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1Y4T5@135624|Aeromonadales	135624|Aeromonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158380_k127_3636605_3	563192.HMPREF0179_03201	1.638e-125	415.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
SRR25158380_k127_3636605_5	1211813.CAPH01000023_gene1940	9e-92	318.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,2G0CZ@200643|Bacteroidia,22UN6@171550|Rikenellaceae	976|Bacteroidetes	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
SRR25158380_k127_3636605_2	861299.J421_0276	7.245e-150	486.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8
SRR25158380_k127_3636605_0	1382359.JIAL01000001_gene2764	1.082e-185	591.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3636605_4	234267.Acid_6478	3.139e-102	339.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158380_k127_3636605_1	251221.35211983	3.444e-156	519.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3646182_0	945713.IALB_2907	1.707e-48	199.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158380_k127_3655523_3	1123405.AUMM01000026_gene2159	3.049e-13	79.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,26NAB@186821|Sporolactobacillaceae	91061|Bacilli	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158380_k127_3655523_1	861299.J421_3206	1.523e-17	89.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158380_k127_3655523_0	861299.J421_3205	6.046e-77	271.0	COG1159@1|root,COG1159@2|Bacteria,1ZUSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158380_k127_3655523_2	929703.KE386491_gene280	1.538e-16	80.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,47Q5C@768503|Cytophagia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_365772_2	379066.GAU_2526	2.845e-23	102.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
SRR25158380_k127_365772_0	861299.J421_3987	8.347e-197	626.0	COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_365772_3	861299.J421_3986	6.114e-23	105.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilE	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl
SRR25158380_k127_365772_1	861299.J421_1152	2.703e-30	125.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158380_k127_365772_4	243231.GSU2041	1.49e-20	95.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U83@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3725140_0	1089553.Tph_c09340	4.312e-218	696.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158380_k127_3725140_1	644966.Tmar_0590	2.54e-30	124.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3WDHJ@538999|Clostridiales incertae sedis	186801|Clostridia	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
SRR25158380_k127_3746082_5	518766.Rmar_0068	7.894e-55	194.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1FIVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_3746082_2	483219.LILAB_29130	2.693e-88	313.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42U6K@68525|delta/epsilon subdivisions,2WQ4K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
SRR25158380_k127_3746082_0	1278073.MYSTI_03750	9.652e-130	425.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3746082_4	861299.J421_0327	1.152e-57	208.0	COG4117@1|root,COG4117@2|Bacteria,1ZUUH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
SRR25158380_k127_3746082_3	404589.Anae109_3628	5.97e-62	221.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria	1224|Proteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158380_k127_3746082_6	861299.J421_2221	5.996e-36	152.0	2ECQU@1|root,336NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158380_k127_3746082_1	404589.Anae109_0005	2.005e-99	332.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158380_k127_3748813_7	573061.Clocel_1446	1.875e-12	70.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,36E2C@31979|Clostridiaceae	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158380_k127_3748813_6	379066.GAU_1713	2.602e-28	119.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158380_k127_3748813_4	1108045.GORHZ_084_00270	1.691e-44	181.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4GAY3@85026|Gordoniaceae	201174|Actinobacteria	S	Transporter associated domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158380_k127_3748813_5	1051632.TPY_0717	4.024e-38	161.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158380_k127_3748813_2	1454007.JAUG01000003_gene3074	6.803e-108	370.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158380_k127_3748813_1	1499967.BAYZ01000027_gene1809	5.495e-113	383.0	COG0661@1|root,COG0661@2|Bacteria	2|Bacteria	I	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	aarF	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158380_k127_3748813_0	861299.J421_1944	1.43e-216	688.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
SRR25158380_k127_3748813_3	379066.GAU_1710	6.256e-49	178.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158380_k127_3756548_5	292415.Tbd_2614	2.302e-11	74.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VSW6@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_3756548_1	349124.Hhal_1918	2.069e-95	319.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,1WXTU@135613|Chromatiales	135613|Chromatiales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_3756548_0	502025.Hoch_0325	8.328e-225	721.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,42PQC@68525|delta/epsilon subdivisions,2WJ8K@28221|Deltaproteobacteria,2YY7H@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_3756548_2	1123368.AUIS01000028_gene1325	2.76e-92	318.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
SRR25158380_k127_3756548_3	1267534.KB906756_gene712	9.265e-38	162.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3758018_0	472759.Nhal_3311	2.13e-129	437.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158380_k127_3758018_1	861299.J421_2693	3.203e-34	144.0	COG2380@1|root,COG2380@2|Bacteria,1ZUZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3772851_3	861299.J421_3743	1.165e-32	139.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158380_k127_3772851_4	378806.STAUR_8052	0.0002432	50.0	2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3772851_0	379066.GAU_2702	1.608e-90	317.0	COG2084@1|root,COG2084@2|Bacteria,1ZT54@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158380_k127_3772851_2	1123371.ATXH01000008_gene246	1.16e-49	186.0	COG1528@1|root,COG1528@2|Bacteria,2GGRA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158380_k127_3772851_1	204669.Acid345_1547	1.678e-76	271.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria,2JMMW@204432|Acidobacteriia	204432|Acidobacteriia	L	IMS family HHH motif	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158380_k127_3782346_0	1173027.Mic7113_4293	9.363e-249	794.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2461@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_3782346_1	1183438.GKIL_2649	5.072e-66	232.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
SRR25158380_k127_3782380_2	861299.J421_3758	4.548e-59	214.0	COG0626@1|root,COG0626@2|Bacteria,1ZUSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
SRR25158380_k127_3782380_3	861299.J421_3756	3.936e-24	111.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3782380_0	861299.J421_3755	8.605e-104	360.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3782380_1	861299.J421_3754	3.765e-100	337.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3782380_4	861299.J421_3753	6.935e-05	45.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158380_k127_3787248_3	1121430.JMLG01000005_gene776	8.315e-50	186.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,2606W@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_3787248_1	580327.Tthe_0562	3.024e-66	237.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,42GD7@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158380_k127_3787248_2	266117.Rxyl_1104	1.886e-51	192.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CQ9Q@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158380_k127_3787248_4	861299.J421_3863	8.671e-41	162.0	COG0494@1|root,COG0494@2|Bacteria,1ZTYK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158380_k127_3787248_0	410359.Pcal_0137	2.382e-84	286.0	COG0107@1|root,arCOG00617@2157|Archaea,2XQ5E@28889|Crenarchaeota	28889|Crenarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158380_k127_3787248_5	1382356.JQMP01000001_gene1018	2.188e-26	126.0	COG3420@1|root,COG3420@2|Bacteria,2GBD6@200795|Chloroflexi,27YVB@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158380_k127_3794967_0	379066.GAU_0578	6.004e-152	485.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3794967_1	861299.J421_2500	2.338e-72	258.0	COG0642@1|root,COG0642@2|Bacteria,1ZTZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_3799770_2	1042375.AFPL01000045_gene1137	6.355e-07	52.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,1RNY1@1236|Gammaproteobacteria,46A35@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	KR domain	-	-	1.1.1.304,1.1.1.76	ko:K03366	ko00650,map00650	-	R02855,R02946,R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_3799770_1	671143.DAMO_2649	1.24e-45	171.0	COG2154@1|root,COG2154@2|Bacteria,2NQ7C@2323|unclassified Bacteria	2|Bacteria	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	3.5.4.33,4.2.1.96	ko:K01724,ko:K11991	ko00790,map00790	-	R04734,R10223	RC00477,RC01208	ko00000,ko00001,ko01000,ko03016,ko04147	-	-	-	Polyketide_cyc2,Pterin_4a
SRR25158380_k127_3799770_0	1380390.JIAT01000010_gene4319	2.872e-147	481.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158380_k127_380772_0	1379270.AUXF01000001_gene2637	4.473e-83	299.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158380_k127_380772_1	861299.J421_4371	4.017e-81	287.0	COG1215@1|root,COG1215@2|Bacteria,1ZU0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158380_k127_380772_2	935567.JAES01000028_gene2708	1.897e-72	255.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1X4TC@135614|Xanthomonadales	135614|Xanthomonadales	V	proteins, homologs of microcin C7 resistance protein MccF	ldcA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158380_k127_380772_4	880073.Calab_0866	2.573e-50	191.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
SRR25158380_k127_380772_6	756272.Plabr_3324	1.156e-12	71.0	COG2331@1|root,COG2331@2|Bacteria,2J18U@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158380_k127_380772_5	379066.GAU_2716	2.625e-39	156.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158380_k127_380772_3	1379270.AUXF01000001_gene2649	1.3e-53	193.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158380_k127_381280_3	861299.J421_3700	5.321e-17	91.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158380_k127_381280_2	861299.J421_0253	7.464e-20	92.0	COG2388@1|root,COG2388@2|Bacteria	2|Bacteria	S	GCN5-related N-acetyl-transferase	HA62_12640	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158380_k127_381280_1	926550.CLDAP_37020	2.383e-104	344.0	COG2746@1|root,COG2746@2|Bacteria,2G6YM@200795|Chloroflexi	200795|Chloroflexi	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
SRR25158380_k127_381280_0	1123242.JH636434_gene3744	1.672e-168	547.0	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158380_k127_3813422_2	1123267.JONN01000001_gene1968	1.277e-48	176.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria,2K0G7@204457|Sphingomonadales	204457|Sphingomonadales	M	Membrane bound O-acyl transferase, MBOAT family protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158380_k127_3813422_0	861299.J421_1344	1.253e-101	335.0	COG0262@1|root,COG0262@2|Bacteria,1ZVA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158380_k127_3813422_1	365046.Rta_06820	2.314e-78	265.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158380_k127_3813618_1	861299.J421_3748	5.69e-43	176.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	BatA,CARDB,F5_F8_type_C,HemolysinCabind,Laminin_G_3,NIDO,VWA_2
SRR25158380_k127_3813618_0	518766.Rmar_2754	1.299e-235	766.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1FIP1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158380_k127_3816387_5	861299.J421_3455	8.862e-20	89.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158380_k127_3816387_4	861299.J421_3454	1.434e-20	99.0	COG2172@1|root,COG2172@2|Bacteria,1ZU34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158380_k127_3816387_0	861299.J421_3453	2.537e-95	337.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1ZSPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
SRR25158380_k127_3816387_1	861299.J421_3452	1.514e-61	228.0	COG0030@1|root,COG0030@2|Bacteria,1ZT2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158380_k127_3816387_2	861299.J421_3451	1.487e-60	239.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158380_k127_3816387_3	234267.Acid_0057	2.713e-44	165.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_3820148_2	861299.J421_0903	1.185e-88	298.0	COG0249@1|root,COG0249@2|Bacteria,1ZST5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158380_k127_3820148_3	1219375.CM002139_gene2118	1.378e-10	73.0	COG0810@1|root,COG0810@2|Bacteria,1NHEC@1224|Proteobacteria,1T6H8@1236|Gammaproteobacteria,1X7HB@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0810 Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158380_k127_3820148_0	1379270.AUXF01000002_gene1158	1.712e-183	597.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158380_k127_3820148_1	471852.Tcur_3455	2.164e-113	376.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4EI19@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158380_k127_3828188_0	1267534.KB906756_gene683	4.81e-110	371.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	ko:K03420,ko:K13525,ko:K17681	ko03050,ko04141,ko05134,map03050,map04141,map05134	M00343,M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko03029,ko03051,ko04131,ko04147	3.A.16.1	-	-	AAA
SRR25158380_k127_3828188_3	927677.ALVU02000001_gene1407	5.772e-24	108.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3828188_1	1173026.Glo7428_4069	1.791e-78	289.0	COG4711@1|root,COG4711@2|Bacteria,1G0HT@1117|Cyanobacteria	1117|Cyanobacteria	S	integral membrane protein TIGR02587	-	-	-	-	-	-	-	-	-	-	-	-	DUF2391
SRR25158380_k127_3828188_2	398720.MED217_08240	1.456e-75	283.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_3832382_7	861299.J421_3520	1.338e-42	164.0	COG4464@1|root,COG4464@2|Bacteria,1ZTQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_3832382_5	861299.J421_3519	2.624e-54	205.0	COG0279@1|root,COG0279@2|Bacteria,1ZTY5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158380_k127_3832382_3	379066.GAU_1912	1.046e-75	271.0	COG1028@1|root,COG1028@2|Bacteria,1ZTJK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_3832382_4	861299.J421_3517	1.498e-72	256.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158380_k127_3832382_2	861299.J421_3513	3.641e-95	335.0	COG0617@1|root,COG0617@2|Bacteria,1ZSKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158380_k127_3832382_6	861299.J421_3509	1.325e-53	212.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	zupT	-	-	ko:K07238,ko:K11021,ko:K16267	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5	-	-	Zip
SRR25158380_k127_3832382_0	861299.J421_3508	8.129e-183	589.0	COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158380_k127_3832382_8	861299.J421_3507	1.968e-17	92.0	COG5608@1|root,COG5608@2|Bacteria,1ZTWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR25158380_k127_3832382_1	861299.J421_3506	1.148e-141	462.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158380_k127_3840657_4	595536.ADVE02000001_gene3964	1.396e-15	85.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2TV0X@28211|Alphaproteobacteria,36XEI@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_76,Thioredox_DsbH
SRR25158380_k127_3840657_1	224719.Abm4_1672	4.667e-56	199.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,23P0H@183925|Methanobacteria	183925|Methanobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158380_k127_3840657_0	861299.J421_2433	1.066e-70	244.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158380_k127_3840657_2	314278.NB231_02168	8.896e-53	203.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158380_k127_3843229_4	67352.JODS01000018_gene5684	3.359e-13	82.0	COG1802@1|root,COG1802@2|Bacteria,2IS8U@201174|Actinobacteria	201174|Actinobacteria	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158380_k127_3843229_2	861299.J421_2574	1.216e-55	208.0	2F9YP@1|root,3427Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3843229_1	483219.LILAB_02920	2.879e-60	222.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158380_k127_3843229_3	1121405.dsmv_1643	5.608e-37	145.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,42TWN@68525|delta/epsilon subdivisions,2WQDD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158380_k127_3843229_0	518766.Rmar_0089	1.458e-174	558.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158380_k127_3861836_0	866536.Belba_1125	4.076e-141	478.0	COG3408@1|root,COG3408@2|Bacteria,4NHUB@976|Bacteroidetes,47N0U@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
SRR25158380_k127_3861836_3	1173024.KI912148_gene2668	8.611e-19	100.0	2DP2V@1|root,330AH@2|Bacteria,1G6YE@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
SRR25158380_k127_3861836_2	861299.J421_4223	8.52e-85	299.0	COG0531@1|root,COG0531@2|Bacteria,1ZSZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158380_k127_3861836_1	861299.J421_5978	3.035e-115	378.0	COG1940@1|root,COG1940@2|Bacteria,1ZSZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
SRR25158380_k127_3896310_0	861299.J421_2591	3.263e-225	721.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158380_k127_3896310_1	290397.Adeh_1044	1.845e-141	455.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2YU10@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158380_k127_3903249_6	379066.GAU_1771	4.558e-21	108.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158380_k127_3903249_1	861299.J421_3408	9.476e-107	350.0	COG0020@1|root,COG0020@2|Bacteria,1ZSNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158380_k127_3903249_4	379066.GAU_1773	3.656e-59	222.0	COG0233@1|root,COG0233@2|Bacteria,1ZTI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158380_k127_3903249_2	1379270.AUXF01000006_gene121	7.912e-84	294.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158380_k127_3903249_3	1123373.ATXI01000001_gene440	2.506e-64	227.0	COG0264@1|root,COG0264@2|Bacteria,2GHDX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158380_k127_3903249_0	1379270.AUXF01000006_gene119	6.802e-108	358.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158380_k127_3903249_5	1379270.AUXF01000006_gene118	4.723e-27	111.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158380_k127_3904271_1	379066.GAU_1946	1.505e-96	325.0	COG1087@1|root,COG1087@2|Bacteria,1ZSX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158380_k127_3904271_3	1379270.AUXF01000006_gene14	4.264e-52	199.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
SRR25158380_k127_3904271_5	861299.J421_3553	2.149e-38	147.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158380_k127_3904271_8	861299.J421_3552	6.546e-31	131.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
SRR25158380_k127_3904271_2	861299.J421_3551	4.902e-91	325.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158380_k127_3904271_7	379066.GAU_1941	1.355e-33	141.0	COG2885@1|root,COG2885@2|Bacteria,1ZTSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158380_k127_3904271_6	861299.J421_3549	7.179e-36	153.0	COG1729@1|root,COG1729@2|Bacteria,1ZTU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
SRR25158380_k127_3904271_4	868864.Dester_0938	1.748e-39	170.0	COG0805@1|root,COG0805@2|Bacteria,2G41B@200783|Aquificae	200783|Aquificae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158380_k127_3904271_0	861299.J421_3547	2.403e-112	398.0	COG1452@1|root,COG1452@2|Bacteria,1ZT14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3928305_0	234267.Acid_3826	1.701e-75	268.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158380_k127_3928305_2	886293.Sinac_1864	5.078e-62	237.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158380_k127_3928305_1	330214.NIDE3346	1.36e-66	237.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_3928975_2	1499967.BAYZ01000090_gene4954	4.172e-44	180.0	COG0500@1|root,COG2226@2|Bacteria,2NQZU@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158380_k127_3928975_1	472759.Nhal_3310	8.105e-66	248.0	COG0451@1|root,COG0451@2|Bacteria,1PG2X@1224|Proteobacteria,1RWX5@1236|Gammaproteobacteria,1X0Z7@135613|Chromatiales	135613|Chromatiales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158380_k127_3928975_0	1121430.JMLG01000002_gene1226	3.021e-126	421.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,26040@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158380_k127_3928975_5	1304874.JAFY01000002_gene1049	3.957e-16	89.0	COG0726@1|root,COG0726@2|Bacteria,3TAKV@508458|Synergistetes	508458|Synergistetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158380_k127_3928975_3	671143.DAMO_2983	4.326e-40	167.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	2.4.1.11,2.4.1.345	ko:K08256,ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292,R11702	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_3928975_4	319225.Plut_1232	4.498e-26	115.0	COG4191@1|root,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158380_k127_3933000_1	1356852.N008_09215	8.15e-131	436.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
SRR25158380_k127_3933000_0	1124780.ANNU01000020_gene3300	1.577e-212	672.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47P0R@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
SRR25158380_k127_3933316_8	195522.BD01_1331	2.822e-11	74.0	COG1210@1|root,arCOG00665@2157|Archaea,2XTI6@28890|Euryarchaeota,244XT@183968|Thermococci	183968|Thermococci	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_3933316_7	483219.LILAB_09920	1.657e-14	84.0	COG0558@1|root,COG0558@2|Bacteria,1P9BV@1224|Proteobacteria,432CD@68525|delta/epsilon subdivisions,2WX7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158380_k127_3933316_3	656519.Halsa_2115	2.628e-21	105.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,24NPX@186801|Clostridia,3WBZN@53433|Halanaerobiales	186801|Clostridia	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158380_k127_3933316_6	861299.J421_4201	1.193e-17	85.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3933316_1	1379270.AUXF01000001_gene2790	3.207e-44	170.0	COG1651@1|root,COG1651@2|Bacteria,1ZTKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_3933316_0	290397.Adeh_0949	1.914e-259	813.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158380_k127_3933316_9	1449346.JQMO01000003_gene3396	1.26e-06	54.0	COG1366@1|root,COG1366@2|Bacteria,2IKUF@201174|Actinobacteria,2M3IS@2063|Kitasatospora	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158380_k127_3933316_4	67257.JODR01000019_gene4015	3.841e-21	97.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_3933316_2	1382306.JNIM01000001_gene130	3.455e-37	148.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158380_k127_3935115_0	365046.Rta_14620	2.848e-134	436.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VH0E@28216|Betaproteobacteria,4AC67@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_3938781_0	1379270.AUXF01000003_gene3650	1.84e-87	306.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1ZSX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158380_k127_3938781_1	926560.KE387023_gene2468	6.852e-32	135.0	COG1285@1|root,COG1285@2|Bacteria,1WMQN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158380_k127_3945538_1	861299.J421_4105	0.0009561	48.0	COG5492@1|root,COG5492@2|Bacteria,1ZUA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
SRR25158380_k127_3945538_0	861299.J421_3566	8.433e-36	145.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158380_k127_3948580_0	1379270.AUXF01000004_gene2956	3.548e-87	296.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158380_k127_3948580_1	379066.GAU_0939	2.129e-43	175.0	COG0860@1|root,COG0860@2|Bacteria,1ZT6J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRR25158380_k127_3963922_3	379066.GAU_0096	4.805e-33	142.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
SRR25158380_k127_3963922_2	869210.Marky_0131	2.808e-39	153.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
SRR25158380_k127_3963922_1	1379270.AUXF01000001_gene2397	1.474e-42	167.0	COG2345@1|root,COG2345@2|Bacteria,1ZTKU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158380_k127_3963922_0	861299.J421_2090	9.112e-236	746.0	COG0719@1|root,COG0719@2|Bacteria,1ZSMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158380_k127_3977397_0	1128421.JAGA01000001_gene2203	2.404e-179	580.0	COG4579@1|root,COG4579@2|Bacteria	2|Bacteria	F	[isocitrate dehydrogenase (NADP+)] phosphatase activity	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
SRR25158380_k127_3977397_1	1120972.AUMH01000004_gene1397	1.05e-40	153.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,278W0@186823|Alicyclobacillaceae	91061|Bacilli	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_3988278_2	861299.J421_4261	7.371e-43	163.0	COG4243@1|root,COG4243@2|Bacteria,1ZTVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158380_k127_3988278_3	1379698.RBG1_1C00001G1442	4.474e-31	128.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158380_k127_3988278_1	243230.DR_2547	1.398e-52	201.0	COG0373@1|root,COG0373@2|Bacteria,1WIN9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158380_k127_3988278_0	1379270.AUXF01000001_gene2546	6.339e-165	526.0	COG0276@1|root,COG0276@2|Bacteria,1ZTW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158380_k127_3988278_4	861299.J421_0272	5.235e-18	84.0	COG2197@1|root,COG2197@2|Bacteria,1ZTJ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158380_k127_3988536_4	861299.J421_0422	1.264e-31	125.0	COG0189@1|root,COG0189@2|Bacteria,1ZTDE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3988536_1	861299.J421_0421	5.158e-166	535.0	COG2308@1|root,COG2308@2|Bacteria,1ZT4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158380_k127_3988536_0	861299.J421_0420	4.814e-176	559.0	COG2170@1|root,COG2170@2|Bacteria,1ZTBN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158380_k127_3988536_3	1379270.AUXF01000005_gene628	1.645e-94	316.0	COG2071@1|root,COG2071@2|Bacteria,1ZSXR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158380_k127_3988536_2	2074.JNYD01000022_gene1521	1.52e-105	355.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158380_k127_3988536_5	379066.GAU_0469	1.456e-06	57.0	28UVI@1|root,2ZGZI@2|Bacteria,1ZU6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3988536_6	861299.J421_2372	0.0002938	48.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158380_k127_4015572_3	861299.J421_2973	2.436e-32	128.0	COG0346@1|root,COG0346@2|Bacteria,1ZTMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158380_k127_4015572_5	1379270.AUXF01000005_gene561	3.82e-07	58.0	28ZEQ@1|root,2ZM6A@2|Bacteria,1ZU2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4015572_0	379066.GAU_1247	9.39e-84	284.0	COG0854@1|root,COG0854@2|Bacteria,1ZSPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SRR25158380_k127_4015572_4	861299.J421_2970	4.944e-16	92.0	2CB0K@1|root,343GC@2|Bacteria,1ZU4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
SRR25158380_k127_4015572_1	861299.J421_2969	2.283e-44	177.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158380_k127_4015572_2	234267.Acid_7097	4.028e-37	158.0	COG1947@1|root,COG1947@2|Bacteria,3Y55D@57723|Acidobacteria	57723|Acidobacteria	I	GHMP kinases N terminal domain	-	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_4029342_0	861299.J421_2988	3.309e-94	338.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4029342_1	1088721.NSU_1093	8.761e-33	143.0	COG2244@1|root,COG2244@2|Bacteria,1NX2R@1224|Proteobacteria,2USND@28211|Alphaproteobacteria,2KAHK@204457|Sphingomonadales	204457|Sphingomonadales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4034038_1	1150626.PHAMO_280239	9.041e-75	263.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,2TVNU@28211|Alphaproteobacteria,2JRTM@204441|Rhodospirillales	204441|Rhodospirillales	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158380_k127_4034038_0	1089553.Tph_c02670	6.924e-82	287.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,42EVR@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851,ko:K13007	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158380_k127_4034038_2	861299.J421_3492	2.947e-45	179.0	COG3765@1|root,COG3765@2|Bacteria,1ZV56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4040552_1	383372.Rcas_1024	4.566e-169	544.0	COG1201@1|root,COG1201@2|Bacteria	2|Bacteria	L	RNA secondary structure unwinding	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158380_k127_4040552_3	1123242.JH636436_gene541	6.85e-103	344.0	COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4040552_4	861299.J421_3014	6.735e-38	143.0	2DJKR@1|root,32X86@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4040552_0	1379270.AUXF01000001_gene1999	7.998e-205	664.0	COG1793@1|root,COG1793@2|Bacteria,1ZTSB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA ligase N terminus	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_4040552_2	1379270.AUXF01000001_gene2003	2.577e-154	494.0	COG1236@1|root,COG1236@2|Bacteria,1ZTZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_4040552_5	269797.Mbar_A2345	1.319e-18	87.0	COG2032@1|root,arCOG05224@2157|Archaea,2Y3M1@28890|Euryarchaeota,2NAVG@224756|Methanomicrobia	224756|Methanomicrobia	P	Copper/zinc superoxide dismutase (SODC)	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
SRR25158380_k127_4047383_1	318996.AXAZ01000001_gene4622	1.255e-46	183.0	COG0596@1|root,COG0596@2|Bacteria,1PJSP@1224|Proteobacteria,2U33J@28211|Alphaproteobacteria,3JXQ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158380_k127_4047383_2	1116472.MGMO_69c00080	3.416e-36	144.0	COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,1SCE7@1236|Gammaproteobacteria,1XFBK@135618|Methylococcales	135618|Methylococcales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158380_k127_4047383_4	234267.Acid_4150	4.815e-16	81.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR25158380_k127_4047383_0	1167006.UWK_01068	2.279e-287	928.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158380_k127_4047383_3	290397.Adeh_3942	7.001e-34	141.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_4059321_0	1121422.AUMW01000007_gene3161	6.495e-219	700.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158380_k127_4059321_1	379066.GAU_1282	4.47e-43	182.0	COG2372@1|root,COG2372@2|Bacteria,1ZTUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR25158380_k127_4081090_0	1379270.AUXF01000001_gene2822	4.992e-165	559.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
SRR25158380_k127_4081090_1	861299.J421_4162	1.149e-82	296.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR25158380_k127_4081090_2	379066.GAU_2573	5.06e-46	180.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR25158380_k127_4094028_1	861299.J421_3916	2.561e-93	318.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158380_k127_4094028_7	99598.Cal7507_4954	1.155e-15	79.0	COG0694@1|root,COG0694@2|Bacteria,1G7UJ@1117|Cyanobacteria,1HP8I@1161|Nostocales	1117|Cyanobacteria	O	PFAM NifU-like domain	nifU	-	-	-	-	-	-	-	-	-	-	-	NifU
SRR25158380_k127_4094028_0	861299.J421_3915	1.118e-120	401.0	COG0489@1|root,COG0489@2|Bacteria,1ZSW7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158380_k127_4094028_9	335283.Neut_1254	6.28e-07	56.0	2C85H@1|root,33H5Y@2|Bacteria,1NJ1W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4094028_2	861299.J421_3913	2.147e-61	226.0	COG1912@1|root,COG1912@2|Bacteria,1ZTIH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158380_k127_4094028_3	1267535.KB906767_gene341	6.615e-48	178.0	28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158380_k127_4094028_4	861299.J421_3911	4.156e-35	152.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
SRR25158380_k127_4094028_5	861299.J421_3910	1.498e-28	130.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158380_k127_4094028_8	379066.GAU_2443	1.068e-10	70.0	2F9A9@1|root,341MC@2|Bacteria,1ZU0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4094028_6	861299.J421_3908	1.707e-28	115.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4104225_2	1278073.MYSTI_01994	2.223e-98	328.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_4104225_0	483219.LILAB_14520	5.983e-126	414.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2YZ59@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158380_k127_4104225_1	1192034.CAP_6275	1.64e-102	339.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2YX8R@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158380_k127_4112628_2	379066.GAU_1723	3.326e-72	246.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_4112628_1	379066.GAU_1722	9.763e-87	313.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158380_k127_4112628_0	379066.GAU_1721	5.952e-132	452.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158380_k127_4112628_3	1232410.KI421415_gene3071	4.251e-58	211.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TXE@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Tryptophan synthase alpha chain	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158380_k127_4115375_1	379066.GAU_1146	3.975e-60	221.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_4115375_0	215803.DB30_3564	7.939e-61	227.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158380_k127_4115375_2	378806.STAUR_5493	3.083e-17	87.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YXVH@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158380_k127_4115653_1	861299.J421_0690	4.604e-59	211.0	2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_4115653_3	518766.Rmar_0185	0.0001065	51.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1FJWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
SRR25158380_k127_4115653_4	864702.OsccyDRAFT_3917	0.0002958	51.0	COG0515@1|root,COG0515@2|Bacteria,1G3WJ@1117|Cyanobacteria,1H9IQ@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158380_k127_4115653_0	1095769.CAHF01000022_gene181	5.688e-130	428.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VH0E@28216|Betaproteobacteria,473FI@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_4115653_2	1242864.D187_007931	3.903e-20	94.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria,2YV31@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	yliI	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158380_k127_413594_9	1121013.P873_09660	0.0001543	52.0	COG2373@1|root,COG4625@1|root,COG2373@2|Bacteria,COG4625@2|Bacteria,1RDX6@1224|Proteobacteria,1S53I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM outer membrane autotransporter barrel	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
SRR25158380_k127_413594_3	861299.J421_1049	1.424e-65	251.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158380_k127_413594_1	1125863.JAFN01000001_gene886	8.29e-141	458.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_413594_7	387093.SUN_1558	4.136e-26	120.0	COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,42UBJ@68525|delta/epsilon subdivisions,2YP8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_413594_0	861299.J421_2344	3.328e-228	732.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158380_k127_413594_8	861299.J421_1004	2.566e-14	83.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158380_k127_413594_2	379066.GAU_3071	9.345e-120	394.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158380_k127_413594_6	379066.GAU_0068	1.162e-38	153.0	2E7CK@1|root,331VT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_413594_5	1121939.L861_10155	9.37e-57	207.0	COG3963@1|root,COG3963@2|Bacteria,1RATY@1224|Proteobacteria,1S1YM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	methyltransferase	ksgA1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
SRR25158380_k127_413594_4	163908.KB235895_gene5097	6.065e-61	218.0	COG1801@1|root,COG1801@2|Bacteria,1G2CT@1117|Cyanobacteria,1HMVF@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_4137727_1	313596.RB2501_02005	5.403e-25	117.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia	976|Bacteroidetes	H	synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158380_k127_4137727_2	861299.J421_3923	2.882e-17	96.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4137727_0	861299.J421_3922	5.214e-201	638.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158380_k127_4151465_2	1430440.MGMSRv2_2843	4.987e-47	174.0	COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria,2UJSZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4151465_1	886293.Sinac_0981	1.566e-91	307.0	COG2085@1|root,COG2085@2|Bacteria,2J3GA@203682|Planctomycetes	203682|Planctomycetes	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158380_k127_4151465_0	1192034.CAP_7724	4.02e-158	504.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42Z4J@68525|delta/epsilon subdivisions,2WUHY@28221|Deltaproteobacteria,2YWQR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_4151465_3	926550.CLDAP_11810	6.161e-39	153.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.11,2.7.8.41,2.7.8.5,2.7.8.8	ko:K00995,ko:K00999,ko:K08744,ko:K17103	ko00260,ko00562,ko00564,ko01100,ko01110,ko04070,map00260,map00562,map00564,map01100,map01110,map04070	M00093	R01800,R01801,R01802,R02030	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158380_k127_4159995_1	251229.Chro_4222	0.0001504	52.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR25158380_k127_4159995_0	1278073.MYSTI_02176	1.097e-130	436.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158380_k127_4164164_1	317619.ANKN01000042_gene3338	7.913e-58	209.0	COG1981@1|root,COG1981@2|Bacteria,1GBIN@1117|Cyanobacteria,1MMBW@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
SRR25158380_k127_4164164_0	861299.J421_3996	8.949e-105	357.0	COG2954@1|root,COG5607@1|root,COG2954@2|Bacteria,COG5607@2|Bacteria,1ZTYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158380_k127_4164164_2	381666.H16_A2208	1.106e-23	102.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,1K7KF@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
SRR25158380_k127_416573_4	1236973.JCM9157_3138	3.495e-11	74.0	COG1164@1|root,COG1164@2|Bacteria,1U8XY@1239|Firmicutes,4HEV8@91061|Bacilli,1ZC0S@1386|Bacillus	91061|Bacilli	E	Peptidase M3A and M3B thimet oligopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M2,Peptidase_M3
SRR25158380_k127_416573_2	1218084.BBJK01000025_gene2545	3.077e-40	155.0	COG3556@1|root,COG3556@2|Bacteria,1N3XH@1224|Proteobacteria,2VRQ4@28216|Betaproteobacteria,1K72R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
SRR25158380_k127_416573_0	379066.GAU_1126	2.019e-53	190.0	COG2315@1|root,COG2315@2|Bacteria,1ZV10@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158380_k127_416573_1	1347392.CCEZ01000015_gene2776	6.843e-43	169.0	COG1670@1|root,COG1670@2|Bacteria,1UI20@1239|Firmicutes,24HRV@186801|Clostridia,36JDG@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158380_k127_416573_3	2002.JOEQ01000005_gene3526	4.165e-40	158.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4EJ8Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4167543_0	379066.GAU_3081	0.0	1746.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1ZSQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158380_k127_4167543_2	401526.TcarDRAFT_2468	3.569e-166	540.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4H33X@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158380_k127_4167543_1	1382306.JNIM01000001_gene1241	1.709e-216	685.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi	200795|Chloroflexi	H	Thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158380_k127_4167543_3	1095767.CAHD01000241_gene1834	1.468e-23	111.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4F14N@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM Acetolactate synthase, small subunit-like	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158380_k127_4187299_0	861299.J421_1872	5.137e-88	322.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158380_k127_4187299_2	861299.J421_1881	1.388e-62	223.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,PD40
SRR25158380_k127_4187299_3	861299.J421_1880	1.17e-46	171.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158380_k127_4187299_1	861299.J421_1871	2.786e-79	273.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
SRR25158380_k127_4200018_0	1379270.AUXF01000005_gene462	5.91e-71	274.0	COG0515@1|root,COG0515@2|Bacteria,1ZTB4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_4200018_2	861299.J421_4430	1.171e-10	69.0	COG5516@1|root,COG5516@2|Bacteria,1ZTJN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158380_k127_4200018_1	1499967.BAYZ01000038_gene2269	1.062e-37	158.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,PAS_3,PAS_9
SRR25158380_k127_4200018_3	379066.GAU_2757	5.898e-07	53.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	soxB	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4246,iECS88_1305.ECS88_4396,iLF82_1304.LF82_624	5_nucleotid_C,Metallophos
SRR25158380_k127_420375_2	1183438.GKIL_1779	1.953e-20	97.0	COG2272@1|root,COG3187@1|root,COG2272@2|Bacteria,COG3187@2|Bacteria,1GA7U@1117|Cyanobacteria	1117|Cyanobacteria	O	META domain	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	META
SRR25158380_k127_420375_1	469383.Cwoe_3127	6.798e-53	205.0	28NWQ@1|root,2ZBUI@2|Bacteria,2IGY4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_420375_0	1300345.LF41_1080	2.599e-144	472.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1XA6G@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4219208_1	861299.J421_3284	2.058e-128	421.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158380_k127_4219208_0	1379698.RBG1_1C00001G1061	5.227e-161	522.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158380_k127_4219208_3	706587.Desti_2761	8.935e-99	342.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2MSIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158380_k127_4219208_2	861299.J421_3281	1.526e-120	419.0	COG1109@1|root,COG1109@2|Bacteria,1ZSP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_4220212_0	861299.J421_3786	2.201e-184	584.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158380_k127_4220212_1	1107311.Q767_04415	3.538e-27	119.0	COG1917@1|root,COG1917@2|Bacteria,4P8ZN@976|Bacteroidetes,1IBWR@117743|Flavobacteriia,2NZNU@237|Flavobacterium	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4220775_0	861299.J421_2742	1.095e-237	748.0	COG1138@1|root,COG1138@2|Bacteria,1ZTBY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158380_k127_4220775_1	861299.J421_2743	5.1e-21	109.0	COG3088@1|root,COG3088@2|Bacteria,1ZTS7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158380_k127_4220775_2	1379270.AUXF01000004_gene3073	1.504e-20	104.0	29W2Z@1|root,30HMM@2|Bacteria,1ZTXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4228743_4	861299.J421_3238	3.913e-45	168.0	COG0789@1|root,COG0789@2|Bacteria,1ZTSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158380_k127_4228743_0	861299.J421_3239	3.837e-91	311.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158380_k127_4228743_2	861299.J421_3240	4.014e-72	261.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158380_k127_4228743_1	1356852.N008_11050	1.563e-83	283.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,47NAX@768503|Cytophagia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158380_k127_4228743_5	243230.DR_0929	3.314e-13	80.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
SRR25158380_k127_4228743_3	1242864.D187_008882	7.133e-52	194.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158380_k127_4232122_0	379066.GAU_2002	1.609e-135	439.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
SRR25158380_k127_4232122_2	1151119.KB895499_gene3674	3.773e-23	106.0	2A4IR@1|root,30T5A@2|Bacteria,2H7PW@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1097
SRR25158380_k127_4232122_1	1340493.JNIF01000004_gene473	3.757e-38	149.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4251521_4	861299.J421_3225	4.353e-27	114.0	COG2121@1|root,COG2121@2|Bacteria,1ZTU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR25158380_k127_4251521_1	861299.J421_3226	1.629e-56	215.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158380_k127_4251521_0	861299.J421_3227	3.968e-202	643.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_4251521_3	1238190.AMQY01000014_gene811	1.005e-28	120.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1XJ6M@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158380_k127_4251521_2	1121346.KB899811_gene1559	6.523e-47	177.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,274IB@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_4251521_5	521098.Aaci_1267	1.436e-18	92.0	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli	91061|Bacilli	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
SRR25158380_k127_4254251_0	1122182.KB903813_gene2669	4.413e-72	252.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
SRR25158380_k127_4254251_2	522306.CAP2UW1_3294	1.671e-25	122.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria,1KQ9M@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Formyl transferase, C-terminal domain	pmrIa	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158380_k127_4254251_1	546271.Selsp_0061	4.669e-41	170.0	COG2120@1|root,COG2120@2|Bacteria,1UZDV@1239|Firmicutes,4H7IU@909932|Negativicutes	909932|Negativicutes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158380_k127_4257285_3	1121920.AUAU01000004_gene598	8.739e-13	80.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SRR25158380_k127_4257285_1	926550.CLDAP_31300	3.868e-45	188.0	COG0647@1|root,COG0647@2|Bacteria,2G6UI@200795|Chloroflexi	200795|Chloroflexi	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158380_k127_4257285_2	1379270.AUXF01000005_gene516	7.803e-22	111.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158380_k127_4257285_0	861299.J421_0444	9.987e-191	605.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_4267010_1	47716.JOFH01000002_gene6299	0.0007442	43.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158380_k127_4270248_2	1380390.JIAT01000010_gene4330	1.72e-32	129.0	COG2457@1|root,COG2457@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF447)	-	-	-	ko:K09154	-	-	-	-	ko00000	-	-	-	DUF447
SRR25158380_k127_4270248_0	1380390.JIAT01000010_gene4331	3.242e-67	245.0	COG1907@1|root,COG1907@2|Bacteria,2IGTW@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring glycosyl groups	-	-	2.4.2.54	ko:K06984	ko00790,map00790	-	R10337,R11102	-	ko00000,ko00001,ko01000	-	-	-	-
SRR25158380_k127_4270248_1	608538.HTH_0392	5.516e-45	171.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	mxaF	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
SRR25158380_k127_4279202_1	1304865.JAGF01000001_gene3317	2.259e-118	387.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_4279202_0	290397.Adeh_3915	1.903e-144	464.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
SRR25158380_k127_4279202_2	290397.Adeh_3916	3.431e-07	52.0	COG0842@1|root,COG0842@2|Bacteria,1R3XD@1224|Proteobacteria	1224|Proteobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158380_k127_4280760_1	1121904.ARBP01000012_gene1301	1.754e-78	278.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4280760_0	1192034.CAP_0948	5.449e-199	630.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria,2YXDW@29|Myxococcales	28221|Deltaproteobacteria	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158380_k127_4280760_2	1206726.BAFV01000015_gene800	5.735e-53	197.0	COG1917@1|root,COG1917@2|Bacteria,2IGRA@201174|Actinobacteria,4G0PF@85025|Nocardiaceae	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4295310_1	861299.J421_3080	2.497e-65	230.0	COG0206@1|root,COG0206@2|Bacteria,1ZSNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158380_k127_4295310_0	861299.J421_3079	2.27e-126	419.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158380_k127_4295310_3	314271.RB2654_00840	0.0003758	51.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158380_k127_4295310_2	861299.J421_3077	4.327e-64	229.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_4296712_2	404589.Anae109_1731	4.191e-51	185.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2Z1U0@29|Myxococcales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158380_k127_4296712_1	861299.J421_4427	2.234e-58	218.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim,DUF4432,DUF5107
SRR25158380_k127_4296712_0	861299.J421_4428	6.442e-162	520.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158380_k127_4300851_5	452637.Oter_1167	5.686e-82	280.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_4300851_9	362418.IW19_12135	3.639e-32	133.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,2NVZM@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SRR25158380_k127_4300851_8	1379270.AUXF01000005_gene664	9.484e-39	151.0	COG0597@1|root,COG0597@2|Bacteria,1ZTVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158380_k127_4300851_6	1313172.YM304_11060	2.685e-75	274.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4300851_10	861299.J421_3684	1.188e-30	126.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158380_k127_4300851_7	861299.J421_4451	1.029e-66	235.0	COG0590@1|root,COG0590@2|Bacteria	2|Bacteria	FJ	tRNA wobble adenosine to inosine editing	guaD	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
SRR25158380_k127_4300851_1	861299.J421_3816	2.267e-260	818.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158380_k127_4300851_0	309801.trd_1931	0.0	1377.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158380_k127_4300851_2	1283299.AUKG01000002_gene3678	5.149e-260	835.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158380_k127_4300851_4	861299.J421_1950	1.159e-180	617.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	treZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158380_k127_4300851_3	861299.J421_2243	1.073e-243	773.0	COG1523@1|root,COG1523@2|Bacteria,1ZV42@142182|Gemmatimonadetes	2|Bacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158380_k127_4301476_0	661478.OP10G_1068	7.706e-92	309.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158380_k127_4301476_2	926554.KI912656_gene4248	1.306e-36	152.0	2E945@1|root,333D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4301476_1	935567.JAES01000057_gene2928	8.063e-59	215.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria,1X5T4@135614|Xanthomonadales	135614|Xanthomonadales	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
SRR25158380_k127_4303943_1	1192034.CAP_5638	2.503e-66	234.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2X3DW@28221|Deltaproteobacteria,2YUWD@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4303943_3	1123261.AXDW01000018_gene799	5.844e-33	142.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158380_k127_4303943_2	1463879.JOHP01000014_gene2113	1.278e-36	147.0	2CDDX@1|root,3058G@2|Bacteria,2H42J@201174|Actinobacteria	201174|Actinobacteria	E	Alkylmercury lyase	-	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB
SRR25158380_k127_4303943_0	1095769.CAHF01000013_gene3292	1.837e-87	291.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VHSE@28216|Betaproteobacteria,472D1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	adh	-	-	ko:K12957,ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_431305_0	861299.J421_1395	2.935e-122	407.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158380_k127_431305_1	1174684.EBMC1_05919	3.686e-62	220.0	28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,2U5RX@28211|Alphaproteobacteria,2K5KG@204457|Sphingomonadales	204457|Sphingomonadales	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158380_k127_431305_2	1267534.KB906754_gene3486	7.473e-08	62.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_4315568_1	1379270.AUXF01000002_gene1252	1.467e-94	321.0	COG1253@1|root,COG1253@2|Bacteria,1ZUMQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158380_k127_4315568_0	1379270.AUXF01000002_gene1600	1.701e-191	630.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4322821_1	518766.Rmar_1595	1.152e-99	353.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158380_k127_4322821_0	518766.Rmar_1593	1.424e-301	938.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158380_k127_4322821_2	861299.J421_4375	1.351e-52	191.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_4322821_3	1380390.JIAT01000009_gene612	0.0009163	43.0	COG5660@1|root,COG5660@2|Bacteria,2HRSR@201174|Actinobacteria,4CTVV@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158380_k127_4334966_2	1429046.RR21198_0122	1.374e-57	207.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4FY8N@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158380_k127_4334966_0	2002.JOEQ01000003_gene2490	2.221e-141	454.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4EI60@85012|Streptosporangiales	201174|Actinobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_4334966_1	639030.JHVA01000001_gene2732	1.512e-69	250.0	COG0500@1|root,COG2226@2|Bacteria,3Y5HG@57723|Acidobacteria	57723|Acidobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_4334966_5	1122609.AUGT01000017_gene821	1.496e-13	82.0	2BJ23@1|root,32DAR@2|Bacteria,2GXZ1@201174|Actinobacteria	201174|Actinobacteria	S	Methylmuconolactone methyl-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	EthD
SRR25158380_k127_4334966_4	1379270.AUXF01000004_gene2933	2.43e-27	121.0	COG2755@1|root,COG2755@2|Bacteria,1ZU6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4334966_3	1242864.D187_007100	6.824e-45	171.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
SRR25158380_k127_4346122_4	1379270.AUXF01000006_gene233	3.627e-70	256.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158380_k127_4346122_0	861299.J421_3292	8.886e-200	638.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158380_k127_4346122_3	379066.GAU_1660	2.348e-73	252.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158380_k127_4346122_1	861299.J421_3294	2.081e-93	317.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158380_k127_4346122_5	861299.J421_3295	1.369e-36	142.0	COG0838@1|root,COG0838@2|Bacteria,1ZTKK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158380_k127_4346122_2	861299.J421_3296	9.179e-84	280.0	COG0717@1|root,COG0717@2|Bacteria,1ZSN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158380_k127_4349190_1	404589.Anae109_3408	4.973e-43	178.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158380_k127_4349190_0	404380.Gbem_3286	7.468e-105	363.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_4349190_2	7668.SPU_023365-tr	3.815e-08	64.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria	33208|Metazoa	C	positive regulation of proteasomal protein catabolic process	TMTC3	GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158380_k127_4350882_3	379066.GAU_0710	2.902e-45	164.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158380_k127_4350882_2	1267533.KB906737_gene1902	5.376e-77	276.0	COG2215@1|root,COG2215@2|Bacteria,3Y79H@57723|Acidobacteria,2JM3I@204432|Acidobacteriia	204432|Acidobacteriia	S	High-affinity nickel-transport protein	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
SRR25158380_k127_4350882_1	204669.Acid345_0924	3.325e-91	314.0	COG0378@1|root,COG0378@2|Bacteria,3Y3AD@57723|Acidobacteria,2JJ75@204432|Acidobacteriia	204432|Acidobacteriia	KO	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
SRR25158380_k127_4350882_4	204669.Acid345_0925	9.056e-32	133.0	COG0375@1|root,COG0375@2|Bacteria,3Y5WA@57723|Acidobacteria,2JK5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
SRR25158380_k127_4350882_0	1267533.KB906737_gene1741	1.735e-108	359.0	COG0068@1|root,COG0068@2|Bacteria,3Y391@57723|Acidobacteria,2JKF7@204432|Acidobacteriia	204432|Acidobacteriia	O	HypF finger	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158380_k127_435816_2	861299.J421_3702	9.663e-73	247.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158380_k127_435816_0	861299.J421_3703	2.811e-194	611.0	COG3185@1|root,COG3185@2|Bacteria,1ZT62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
SRR25158380_k127_435816_1	584708.Apau_1725	1.83e-92	329.0	COG4191@1|root,COG4191@2|Bacteria,3TBCP@508458|Synergistetes	2|Bacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
SRR25158380_k127_435816_3	379066.GAU_3049	2.884e-38	149.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_435816_4	861299.J421_0441	6.137e-05	54.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158380_k127_436340_4	378806.STAUR_2315	1.04e-31	126.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2YUBK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SRR25158380_k127_436340_5	1313265.JNIE01000002_gene775	4.311e-28	121.0	COG1525@1|root,COG1525@2|Bacteria,2G548@200783|Aquificae	200783|Aquificae	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158380_k127_436340_3	926550.CLDAP_30780	1.586e-99	336.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G719@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158380_k127_436340_6	379066.GAU_2601	0.0002238	52.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_436340_1	861299.J421_3647	1.022e-278	885.0	COG1166@1|root,COG1166@2|Bacteria,1ZST1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SRR25158380_k127_436340_0	861299.J421_4196	4.35e-321	995.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158380_k127_436340_2	234267.Acid_1653	4.903e-128	415.0	COG0372@1|root,COG0372@2|Bacteria,3Y32J@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158380_k127_4368113_2	584708.Apau_0058	1.216e-89	302.0	COG1101@1|root,COG1101@2|Bacteria,3TAS9@508458|Synergistetes	508458|Synergistetes	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158380_k127_4368113_3	1379270.AUXF01000002_gene1589	1.011e-85	292.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1589|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4368113_0	644966.Tmar_1686	0.0	1192.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158380_k127_4368113_4	1379698.RBG1_1C00001G0517	7.884e-23	102.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158380_k127_4368113_6	861299.J421_2404	6.308e-14	79.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4368113_5	861299.J421_2404	5.613e-22	102.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4368113_1	861299.J421_0065	1.484e-144	492.0	COG2120@1|root,COG2120@2|Bacteria,1ZT6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158380_k127_4373332_1	379066.GAU_1556	6.011e-118	396.0	COG0532@1|root,COG0532@2|Bacteria,1ZT5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158380_k127_4373332_2	861299.J421_3187	3.7e-13	76.0	COG1358@1|root,COG1358@2|Bacteria,1ZU1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
SRR25158380_k127_4373332_0	1379270.AUXF01000005_gene820	1.165e-176	559.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
SRR25158380_k127_4409564_0	234267.Acid_0057	3.949e-157	502.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158380_k127_4409564_1	1168034.FH5T_12350	3.327e-74	265.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,2FRKB@200643|Bacteroidia	976|Bacteroidetes	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158380_k127_4409564_2	1379270.AUXF01000006_gene80	5.699e-52	201.0	COG0847@1|root,COG0847@2|Bacteria,1ZTNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158380_k127_4415701_2	1267535.KB906767_gene3148	1.248e-145	464.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158380_k127_4415701_1	1267535.KB906767_gene3147	1.719e-150	496.0	COG0309@1|root,COG0309@2|Bacteria,3Y3UH@57723|Acidobacteria,2JK96@204432|Acidobacteriia	204432|Acidobacteriia	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_4415701_0	1267535.KB906767_gene3146	1.218e-161	535.0	COG0279@1|root,COG0279@2|Bacteria	2|Bacteria	G	D-glycero-D-manno-heptose 7-phosphate metabolic process	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158380_k127_4415701_4	1267535.KB906767_gene3145	7.932e-26	111.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158380_k127_4415701_3	1267533.KB906737_gene1741	3.401e-26	113.0	COG0068@1|root,COG0068@2|Bacteria,3Y391@57723|Acidobacteria,2JKF7@204432|Acidobacteriia	204432|Acidobacteriia	O	HypF finger	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158380_k127_4416623_0	379066.GAU_2144	9.571e-133	431.0	COG1217@1|root,COG1217@2|Bacteria,1ZT8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158380_k127_4416623_2	319003.Bra1253DRAFT_07805	3.082e-71	251.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,3JTI5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	cation efflux	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158380_k127_4416623_1	349163.Acry_2693	1.32e-80	276.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,2JPGF@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158380_k127_4426060_1	861299.J421_3072	6.322e-73	257.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_4426060_0	861299.J421_3073	1.955e-132	432.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158380_k127_4426060_2	861299.J421_3074	1.237e-14	87.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158380_k127_4440725_0	700598.Niako_0029	4.651e-70	245.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_4440725_1	1123226.KB899299_gene3389	5.75e-57	213.0	COG3861@1|root,COG3861@2|Bacteria,1V71H@1239|Firmicutes,4IRSD@91061|Bacilli,276WN@186822|Paenibacillaceae	91061|Bacilli	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,YflT
SRR25158380_k127_4444301_6	1089551.KE386572_gene400	2.813e-06	54.0	COG2244@1|root,COG2244@2|Bacteria,1RFDD@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
SRR25158380_k127_4444301_5	1131553.JIBI01000003_gene1710	8.669e-16	89.0	COG0223@1|root,COG0726@1|root,COG0223@2|Bacteria,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,372SU@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158380_k127_4444301_0	926550.CLDAP_18370	3.012e-136	440.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_4444301_4	861299.J421_3529	1.457e-55	208.0	COG0584@1|root,COG0584@2|Bacteria,1ZTMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158380_k127_4444301_3	1234364.AMSF01000016_gene1722	1.584e-57	211.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,1SA9A@1236|Gammaproteobacteria,1X8PR@135614|Xanthomonadales	135614|Xanthomonadales	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
SRR25158380_k127_4444301_2	266117.Rxyl_2372	1.507e-86	294.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4CQ9H@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158380_k127_4444301_1	880072.Desac_2700	1.319e-132	441.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2MQV1@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
SRR25158380_k127_4455869_2	671143.DAMO_0414	2.67e-10	62.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR25158380_k127_4455869_0	1254432.SCE1572_09230	2.57e-100	334.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YXCH@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_4455869_1	861299.J421_2962	1.494e-97	333.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SRR25158380_k127_4468509_0	756067.MicvaDRAFT_1008	9.691e-68	239.0	COG0400@1|root,COG0400@2|Bacteria,1G3RX@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
SRR25158380_k127_4468509_2	1121875.KB907548_gene1518	1.789e-17	93.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
SRR25158380_k127_4468509_1	861299.J421_4541	1.439e-51	188.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158380_k127_4468509_3	861299.J421_4420	4.739e-09	63.0	COG0296@1|root,COG0296@2|Bacteria,1ZUZV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4476676_0	562970.Btus_2414	4.881e-76	258.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158380_k127_4476676_2	379066.GAU_2017	9.588e-49	186.0	COG1225@1|root,COG1225@2|Bacteria,1ZTY4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_4476676_3	1150599.MPHLEI_17397	0.0007587	49.0	COG5517@1|root,COG5517@2|Bacteria,2IHV4@201174|Actinobacteria,239DS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158380_k127_4476676_1	1379270.AUXF01000003_gene3840	4.143e-58	220.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1ZTDZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SRR25158380_k127_4488286_1	861299.J421_3136	1.374e-21	98.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DctA-YdbH
SRR25158380_k127_4488286_0	648996.Theam_1208	2.35e-104	361.0	COG3276@1|root,COG3276@2|Bacteria,2G3Y1@200783|Aquificae	200783|Aquificae	J	Translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158380_k127_448904_0	479434.Sthe_0159	6.181e-215	679.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2G7US@200795|Chloroflexi,27YN6@189775|Thermomicrobia	189775|Thermomicrobia	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,PDDEXK_1
SRR25158380_k127_4489535_4	1379270.AUXF01000003_gene3485	8.817e-26	109.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158380_k127_4489535_0	861299.J421_3906	6.048e-246	769.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158380_k127_4489535_1	861299.J421_3905	6.878e-85	310.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158380_k127_4489535_2	1379270.AUXF01000003_gene3488	4.632e-75	257.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158380_k127_4489535_3	880073.Calab_3513	2.881e-39	154.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	pip	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Peptidase_S9
SRR25158380_k127_4502695_1	330214.NIDE1168	1.887e-59	217.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_4502695_0	857087.Metme_4252	1.462e-202	634.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,1XDPR@135618|Methylococcales	135618|Methylococcales	G	PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal	-	GO:0003674,GO:0003824,GO:0008150,GO:0009758	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158380_k127_4502789_1	1040986.ATYO01000039_gene4526	2.745e-44	176.0	2FBK1@1|root,343R7@2|Bacteria,1NY88@1224|Proteobacteria,2UTP6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4502789_5	497964.CfE428DRAFT_2422	7.837e-17	87.0	COG4194@1|root,COG4194@2|Bacteria	2|Bacteria	K	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
SRR25158380_k127_4502789_2	309807.SRU_0072	3.859e-35	139.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158380_k127_4502789_4	383372.Rcas_1168	1.538e-17	91.0	COG2161@1|root,COG2161@2|Bacteria,2G9Q0@200795|Chloroflexi	200795|Chloroflexi	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158380_k127_4502789_0	208439.AJAP_18640	8.452e-55	199.0	COG0438@1|root,COG0438@2|Bacteria,2IC1A@201174|Actinobacteria,4E4GM@85010|Pseudonocardiales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_450654_0	1121033.AUCF01000005_gene5309	2.495e-118	399.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales	204441|Rhodospirillales	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158380_k127_450654_3	861299.J421_2991	2.238e-46	184.0	COG0241@1|root,COG0241@2|Bacteria,1ZTT8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158380_k127_450654_2	861299.J421_2990	1.805e-57	207.0	COG0299@1|root,COG0299@2|Bacteria,1ZTKJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158380_k127_450654_1	861299.J421_2989	2.74e-89	306.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158380_k127_4523324_2	502025.Hoch_3456	1.29e-53	194.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158380_k127_4523324_1	296591.Bpro_1826	4.997e-60	223.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158380_k127_4523324_3	1121015.N789_08235	8.04e-44	168.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria,1XATQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4523324_0	1379270.AUXF01000005_gene642	4.479e-147	495.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_4621492_2	1267535.KB906767_gene4135	5.998e-78	270.0	COG3336@1|root,COG3474@1|root,COG3336@2|Bacteria,COG3474@2|Bacteria,3Y6N7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158380_k127_4621492_1	861299.J421_6166	2.57e-107	360.0	COG0628@1|root,COG0628@2|Bacteria,1ZSY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158380_k127_4621492_3	861299.J421_1795	7.746e-52	192.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K06212,ko:K21990,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.4	-	-	Form_Nir_trans
SRR25158380_k127_4621492_0	1267535.KB906767_gene4141	2.915e-228	721.0	COG4993@1|root,COG4993@2|Bacteria,3Y72Y@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
SRR25158380_k127_4694354_3	379066.GAU_1167	6.968e-08	57.0	2FCTB@1|root,344W9@2|Bacteria,1ZU4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4694354_1	861299.J421_6158	9.485e-70	253.0	COG0631@1|root,COG0631@2|Bacteria,1ZSPY@142182|Gemmatimonadetes	2|Bacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158380_k127_4694354_2	211165.AJLN01000107_gene5634	8.957e-41	173.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria,1JIJA@1189|Stigonemataceae	1117|Cyanobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Ras
SRR25158380_k127_4694354_0	1173024.KI912149_gene5318	1.32e-109	376.0	COG2885@1|root,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria,1JGWQ@1189|Stigonemataceae	1117|Cyanobacteria	M	OmpA family	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	OmpA
SRR25158380_k127_4694354_4	32057.KB217478_gene2353	4.109e-06	53.0	COG1322@1|root,COG1322@2|Bacteria,1G77N@1117|Cyanobacteria,1HSB1@1161|Nostocales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4707872_3	861299.J421_2107	1.772e-19	101.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ysmA	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2
SRR25158380_k127_4707872_0	1128421.JAGA01000003_gene2894	7.469e-56	211.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158380_k127_4707872_1	1379270.AUXF01000001_gene2401	8.422e-43	159.0	COG1146@1|root,COG1146@2|Bacteria,1ZU19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_4707872_2	379066.GAU_0096	1.005e-25	113.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
SRR25158380_k127_4733727_3	1340493.JNIF01000003_gene2938	9.075e-22	110.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4733727_1	1379270.AUXF01000004_gene3151	1.192e-35	149.0	COG1512@1|root,COG1512@2|Bacteria,1ZT1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158380_k127_4733727_2	765420.OSCT_0895	4.663e-32	136.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi,377EX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_4733727_0	861299.J421_2641	2.556e-88	308.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158380_k127_473833_3	247639.MGP2080_02481	6.159e-16	78.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JBXZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158380_k127_473833_1	266117.Rxyl_1558	1.607e-119	398.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4CSWG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158380_k127_473833_0	1122612.AUBA01000002_gene1748	5.482e-130	448.0	COG0531@1|root,COG0531@2|Bacteria,1MUP1@1224|Proteobacteria,2U4MC@28211|Alphaproteobacteria,2KBDP@204457|Sphingomonadales	204457|Sphingomonadales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158380_k127_473833_2	99598.Cal7507_0676	2.573e-18	99.0	COG3162@1|root,COG3162@2|Bacteria,1GB35@1117|Cyanobacteria,1HSX2@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
SRR25158380_k127_473833_4	379066.GAU_1153	5.767e-12	72.0	COG4147@1|root,COG4147@2|Bacteria,1ZUA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158380_k127_4754489_2	1120958.AULD01000007_gene1178	4.377e-13	74.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4FKEW@85023|Microbacteriaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158380_k127_4754489_0	1379270.AUXF01000005_gene825	1.831e-80	281.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158380_k127_4754489_1	379066.GAU_1560	7.204e-34	138.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158380_k127_475476_2	1121889.AUDM01000003_gene2329	0.0001931	54.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia,2NSJZ@237|Flavobacterium	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_475476_1	237368.SCABRO_01880	5.255e-85	306.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158380_k127_475476_0	247490.KSU1_C0857	7.094e-124	405.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158380_k127_4758672_1	861299.J421_1277	2.951e-76	276.0	COG4294@1|root,COG4294@2|Bacteria	2|Bacteria	L	response to UV	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
SRR25158380_k127_4758672_0	945713.IALB_0512	3.198e-107	362.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
SRR25158380_k127_4760757_0	690850.Desaf_3625	8.289e-42	162.0	COG3554@1|root,COG3554@2|Bacteria,1RA4K@1224|Proteobacteria	1224|Proteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158380_k127_4760757_2	526227.Mesil_1708	3.757e-31	131.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_4760757_3	1379270.AUXF01000001_gene2745	2.788e-29	125.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158380_k127_4775255_3	326424.FRAAL3165	1.474e-21	106.0	COG1546@1|root,COG1546@2|Bacteria,2IN1Q@201174|Actinobacteria,4EWDW@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4775255_2	1379270.AUXF01000003_gene3588	3.999e-34	136.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
SRR25158380_k127_4775255_0	886293.Sinac_1729	3.081e-119	396.0	COG0501@1|root,COG0501@2|Bacteria,2J0GY@203682|Planctomycetes	203682|Planctomycetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158380_k127_4775255_1	861299.J421_1003	3.103e-92	329.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158380_k127_4799452_1	1122137.AQXF01000003_gene2088	2.467e-55	196.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U0BD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_4799452_0	1183438.GKIL_2082	1.771e-257	810.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1GDGA@1117|Cyanobacteria	1117|Cyanobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158380_k127_4816351_0	1379270.AUXF01000003_gene3474	2.071e-196	619.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158380_k127_4816351_2	426117.M446_3645	2.317e-23	107.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,1JTMF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
SRR25158380_k127_4816351_1	204669.Acid345_3285	2.956e-152	498.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JIFD@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_4816351_3	861299.J421_3920	1.849e-18	90.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4827685_2	1267535.KB906767_gene3148	1.386e-56	201.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158380_k127_4827685_3	1267535.KB906767_gene3149	1.879e-30	123.0	COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria,2JK31@204432|Acidobacteriia	204432|Acidobacteriia	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158380_k127_4827685_0	379066.GAU_3855	1.521e-75	261.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158380_k127_4827685_1	861299.J421_2625	4.358e-59	222.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158380_k127_4828997_1	1283299.AUKG01000001_gene3430	4.777e-126	418.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4CR6R@84995|Rubrobacteria	84995|Rubrobacteria	OT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158380_k127_4828997_2	335659.S23_06950	2.972e-65	248.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
SRR25158380_k127_4828997_0	861299.J421_5987	7.737e-317	993.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158380_k127_4834012_0	1267535.KB906767_gene1523	3.412e-141	470.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	kojP	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158380_k127_4834012_1	861299.J421_6272	1.262e-121	429.0	28MSW@1|root,2ZB15@2|Bacteria,1ZUI9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4846426_0	1379270.AUXF01000007_gene968	1.079e-125	418.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000007_gene968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4846426_1	861299.J421_3956	3.334e-59	211.0	COG0521@1|root,COG0521@2|Bacteria,1ZU2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158380_k127_4846426_2	1267534.KB906754_gene3853	2.034e-17	85.0	2E0D8@1|root,32W02@2|Bacteria,3Y5V4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_485949_5	861299.J421_3753	3.301e-06	55.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158380_k127_485949_1	861299.J421_3752	1.388e-72	276.0	COG0859@1|root,COG0859@2|Bacteria,1ZSYI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158380_k127_485949_0	203119.Cthe_1326	1.177e-246	775.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158380_k127_485949_3	324602.Caur_3095	6.103e-56	223.0	COG0697@1|root,COG0697@2|Bacteria,2G7RS@200795|Chloroflexi,377VC@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158380_k127_485949_2	1358423.N180_21025	1.15e-64	243.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158380_k127_485949_4	661478.OP10G_2288	3.442e-52	192.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
SRR25158380_k127_4879556_1	1379270.AUXF01000003_gene3384	1.111e-105	356.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158380_k127_4879556_0	204669.Acid345_3014	1.883e-118	419.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158380_k127_4879556_3	1203606.HMPREF1526_00891	2.832e-53	199.0	COG0040@1|root,COG3705@1|root,COG0040@2|Bacteria,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,36DWG@31979|Clostridiaceae	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158380_k127_4879556_4	926550.CLDAP_37680	2.811e-50	196.0	COG0040@1|root,COG0040@2|Bacteria	2|Bacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
SRR25158380_k127_4879556_2	861299.J421_3744	5.979e-54	192.0	COG1995@1|root,COG1995@2|Bacteria,1ZT2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158380_k127_4896997_0	379066.GAU_2006	6.863e-97	329.0	COG0531@1|root,COG0531@2|Bacteria,1ZT2B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_4896997_1	379066.GAU_2007	6.066e-12	76.0	2C803@1|root,33Q52@2|Bacteria,1ZTK6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4909038_0	861299.J421_4355	6.949e-92	325.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4909038_1	861299.J421_4356	1.092e-80	289.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_4909038_2	861299.J421_4357	9.893e-60	218.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_4918604_0	1120934.KB894403_gene284	3.383e-134	436.0	COG0535@1|root,COG0535@2|Bacteria,2HGKW@201174|Actinobacteria,4DZZI@85010|Pseudonocardiales	201174|Actinobacteria	S	biosynthesis protein E	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158380_k127_4918604_1	477974.Daud_1126	5.629e-56	210.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,2611J@186807|Peptococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_4918604_3	472759.Nhal_3515	5.782e-38	162.0	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,1RNF7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Transport Permease Protein	pedC	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158380_k127_4918604_2	1379270.AUXF01000001_gene2718	2.051e-43	163.0	COG4454@1|root,COG4454@2|Bacteria,1ZTKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4946576_1	1278073.MYSTI_00693	1.643e-68	241.0	COG0784@1|root,COG0840@1|root,COG2199@1|root,COG2770@1|root,COG5002@1|root,COG0784@2|Bacteria,COG0840@2|Bacteria,COG2770@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2YU1H@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
SRR25158380_k127_4946576_0	404380.Gbem_2406	6.887e-120	414.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158380_k127_495935_1	344747.PM8797T_16675	1.885e-99	352.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158380_k127_495935_2	1448389.BAVQ01000002_gene2863	8.163e-76	265.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158380_k127_495935_4	522373.Smlt3139	2.76e-24	118.0	2DKZK@1|root,310GY@2|Bacteria,1NQ6H@1224|Proteobacteria,1SSKG@1236|Gammaproteobacteria,1X6D8@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
SRR25158380_k127_495935_7	1502850.FG91_01095	2.337e-07	63.0	2DKZK@1|root,310GY@2|Bacteria,1NYGB@1224|Proteobacteria,2UTDG@28211|Alphaproteobacteria,2K6K3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
SRR25158380_k127_495935_3	595537.Varpa_5702	5.943e-36	143.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2VV8S@28216|Betaproteobacteria,4AHZ3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_495935_6	84531.JMTZ01000030_gene195	1.471e-23	115.0	COG2207@1|root,COG2207@2|Bacteria,1QVRF@1224|Proteobacteria,1SMB9@1236|Gammaproteobacteria,1X4Y8@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158380_k127_495935_0	1183438.GKIL_2649	8.989e-118	394.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
SRR25158380_k127_495935_5	404589.Anae109_4072	2.794e-24	111.0	293J8@1|root,2ZR19@2|Bacteria,1R6Y4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4959654_2	379066.GAU_3769	2.089e-42	160.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158380_k127_4959654_0	1499967.BAYZ01000016_gene6546	1.761e-100	359.0	COG0383@1|root,COG0383@2|Bacteria,2NQ98@2323|unclassified Bacteria	2|Bacteria	G	Alpha mannosidase, middle domain	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	2.3.1.204,3.2.1.170,3.2.1.24	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158380_k127_4959654_1	521045.Kole_0682	6.713e-63	227.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
SRR25158380_k127_4962250_1	379066.GAU_2077	8.523e-167	538.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4962250_3	861299.J421_0383	1.261e-150	514.0	COG2234@1|root,COG2234@2|Bacteria,1ZTDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_4962250_6	886293.Sinac_5393	0.0001566	55.0	COG1413@1|root,COG1413@2|Bacteria,2IXTT@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158380_k127_4962250_2	869210.Marky_0572	1.108e-153	493.0	COG0626@1|root,COG0626@2|Bacteria,1WK1T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158380_k127_4962250_0	661478.OP10G_0994	6.65e-184	587.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158380_k127_4962250_5	861299.J421_0341	9.064e-81	294.0	COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_4962250_4	861299.J421_0342	6.128e-84	296.0	COG0642@1|root,COG2205@2|Bacteria,1ZUZJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158380_k127_4962453_2	861299.J421_5949	1.558e-56	217.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_5949|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_4962453_0	1396141.BATP01000059_gene2564	2.033e-141	453.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158380_k127_4962453_1	1379270.AUXF01000002_gene1600	4.212e-94	313.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4967998_0	861299.J421_6152	0.0	2172.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRR25158380_k127_4983801_4	1125863.JAFN01000001_gene3143	2.158e-08	58.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2WKS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_4983801_2	395961.Cyan7425_3759	3.552e-85	291.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria,3KG0I@43988|Cyanothece	1117|Cyanobacteria	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158380_k127_4983801_1	1254432.SCE1572_09420	1.49e-133	435.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,42SJI@68525|delta/epsilon subdivisions,2WPX2@28221|Deltaproteobacteria,2YV2D@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
SRR25158380_k127_4983801_0	1254432.SCE1572_09415	1.452e-140	460.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158380_k127_4983801_3	457570.Nther_2188	3.06e-32	129.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158380_k127_5000128_4	1123368.AUIS01000010_gene2335	1.089e-05	57.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,2NCEN@225057|Acidithiobacillales	225057|Acidithiobacillales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6
SRR25158380_k127_5000128_2	1125863.JAFN01000001_gene1608	1.86e-25	115.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
SRR25158380_k127_5000128_1	309807.SRU_0619	2.927e-86	296.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1FJU8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	RmlD substrate binding domain	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158380_k127_5000128_0	861299.J421_0144	1.709e-177	569.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158380_k127_5000128_3	649747.HMPREF0083_04837	3.749e-17	82.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,274YV@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158380_k127_5007929_2	379066.GAU_1205	1.138e-26	110.0	COG0238@1|root,COG0238@2|Bacteria,1ZU47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158380_k127_5007929_3	1379270.AUXF01000005_gene514	8.748e-26	112.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158380_k127_5007929_1	1120971.AUCA01000005_gene2255	3.321e-58	221.0	COG2258@1|root,COG2258@2|Bacteria,1UB2C@1239|Firmicutes,4HB26@91061|Bacilli,279V0@186823|Alicyclobacillaceae	91061|Bacilli	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SRR25158380_k127_5007929_0	997346.HMPREF9374_2493	1.743e-96	322.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,27BBQ@186824|Thermoactinomycetaceae	91061|Bacilli	J	Protein of unknown function (DUF933)	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158380_k127_5012940_4	861299.J421_1911	2.059e-34	135.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158380_k127_5012940_0	1123229.AUBC01000038_gene4605	1.223e-157	512.0	COG0641@1|root,COG0641@2|Bacteria,1QJ1C@1224|Proteobacteria,2V1ZF@28211|Alphaproteobacteria,3K0C3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_5012940_1	266117.Rxyl_2476	2.317e-143	475.0	COG2271@1|root,COG2271@2|Bacteria,2GIS1@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_5012940_2	395961.Cyan7425_1524	1.037e-59	218.0	COG0628@1|root,COG0628@2|Bacteria,1G1UA@1117|Cyanobacteria,3KH99@43988|Cyanothece	1117|Cyanobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158380_k127_5012940_3	251221.35214825	6.624e-35	136.0	COG2755@1|root,COG3055@1|root,COG2755@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,F5_F8_type_C,Flg_new,Kelch_6,Lipase_GDSL_2
SRR25158380_k127_5033776_3	234267.Acid_0395	7.997e-32	134.0	COG2207@1|root,COG2207@2|Bacteria,3Y7NC@57723|Acidobacteria	57723|Acidobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158380_k127_5033776_1	42256.RradSPS_0124	1.96e-50	199.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158380_k127_5033776_0	521045.Kole_1143	2.738e-57	205.0	COG1704@1|root,COG1704@2|Bacteria,2GCV5@200918|Thermotogae	200918|Thermotogae	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158380_k127_5033776_2	379066.GAU_0196	9.467e-35	141.0	COG0789@1|root,COG0789@2|Bacteria,1ZTHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158380_k127_5051919_1	404589.Anae109_3731	7.885e-99	342.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
SRR25158380_k127_5051919_0	1185876.BN8_01687	5.102e-175	575.0	COG1505@1|root,COG1505@2|Bacteria,4PPNM@976|Bacteroidetes,47YQ9@768503|Cytophagia	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158380_k127_5058937_0	1379270.AUXF01000002_gene1820	1.647e-63	225.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SRR25158380_k127_5058937_1	290397.Adeh_0115	8.025e-61	225.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_5064490_2	1232410.KI421427_gene1294	7.048e-88	296.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,43T9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_7,Oxidored_q6
SRR25158380_k127_5064490_0	243231.GSU0743	2.402e-165	537.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,43SVB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
SRR25158380_k127_5064490_1	290397.Adeh_3658	1.223e-120	398.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2YZXM@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
SRR25158380_k127_5073712_5	572477.Alvin_0590	4.911e-16	92.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1WXM3@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
SRR25158380_k127_5073712_6	1232453.BAIF02000118_gene4616	3.237e-06	60.0	COG1378@1|root,COG1378@2|Bacteria,1V2DD@1239|Firmicutes,24BVS@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
SRR25158380_k127_5073712_3	379066.GAU_2771	3.417e-51	199.0	2EW3S@1|root,33PH0@2|Bacteria,1ZTQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5073712_1	483219.LILAB_20835	3.945e-116	394.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,43E81@68525|delta/epsilon subdivisions,2WZZ4@28221|Deltaproteobacteria,2YU4S@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158380_k127_5073712_4	1379270.AUXF01000004_gene3063	5.968e-39	160.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,Big_5,Exo_endo_phos,LTD,SdiA-regulated,VPEP
SRR25158380_k127_5073712_2	379066.GAU_0535	9.269e-79	291.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158380_k127_5073712_0	935948.KE386494_gene598	2.437e-136	453.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,42FCI@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158380_k127_5114000_0	426117.M446_0777	2.338e-132	428.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,1JXTM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_5114000_1	556268.OFAG_02087	8.878e-38	160.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SRR25158380_k127_5114000_2	861299.J421_3936	4.252e-36	149.0	COG1409@1|root,COG1409@2|Bacteria,1ZTQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158380_k127_528811_0	1096930.L284_07705	6.488e-81	271.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,2K04N@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158380_k127_528811_1	391612.CY0110_13831	3.457e-48	181.0	COG0515@1|root,COG0515@2|Bacteria,1G08U@1117|Cyanobacteria,3KH6Q@43988|Cyanothece	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_2,TPR_8
SRR25158380_k127_528811_2	1386089.N865_11265	5.672e-46	188.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FIBI@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_532893_1	861299.J421_3468	4.539e-137	462.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_532893_3	379066.GAU_1899	2.129e-113	376.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158380_k127_532893_2	861299.J421_3470	9.594e-117	404.0	COG0635@1|root,COG0635@2|Bacteria,1ZSSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_532893_5	1121430.JMLG01000026_gene27	9.111e-69	254.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158380_k127_532893_0	861299.J421_3472	6.578e-138	457.0	COG0536@1|root,COG0536@2|Bacteria,1ZSVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR25158380_k127_532893_6	861299.J421_3473	2.432e-50	186.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158380_k127_532893_9	880073.Calab_0547	6.667e-12	78.0	29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
SRR25158380_k127_532893_4	1379270.AUXF01000006_gene54	1.557e-101	357.0	COG2870@1|root,COG2870@2|Bacteria,1ZT0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
SRR25158380_k127_532893_8	194439.CT1396	3.366e-19	94.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158380_k127_532893_7	1284352.AOIG01000019_gene3695	5.774e-30	130.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,26UNW@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158380_k127_535478_1	1121481.AUAS01000008_gene2993	2.832e-17	91.0	2DBYP@1|root,2ZBWI@2|Bacteria,4PPYC@976|Bacteroidetes,47PBE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_535478_0	1379270.AUXF01000006_gene190	1.024e-96	339.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
SRR25158380_k127_539738_2	761193.Runsl_3865	1.296e-18	87.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158380_k127_539738_3	1280944.HY17_00385	6.932e-15	86.0	COG4319@1|root,COG4319@2|Bacteria,1R2GQ@1224|Proteobacteria,2TZK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158380_k127_539738_0	452637.Oter_2330	2.123e-51	201.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
SRR25158380_k127_539738_1	861299.J421_0341	5.641e-32	144.0	COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_539738_4	981369.JQMJ01000004_gene4589	2.351e-11	68.0	2981C@1|root,2ZV7E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_539738_5	926567.TheveDRAFT_0456	0.0002154	52.0	COG1191@1|root,COG1191@2|Bacteria,3T9TN@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158380_k127_540617_0	1279009.ADICEAN_02558	1.435e-191	613.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
SRR25158380_k127_540617_1	861299.J421_0859	5.822e-82	277.0	COG0346@1|root,COG0346@2|Bacteria,1ZTUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158380_k127_545053_11	1123023.JIAI01000016_gene3498	2.94e-06	51.0	COG0778@1|root,COG0778@2|Bacteria,2I8P3@201174|Actinobacteria,4DYU0@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_545053_9	395965.Msil_1406	1.619e-17	90.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,3N9Q5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
SRR25158380_k127_545053_8	765420.OSCT_0546	2.542e-37	153.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_545053_1	1121861.KB899946_gene3939	2.149e-154	494.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,2JR9U@204441|Rhodospirillales	204441|Rhodospirillales	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158380_k127_545053_3	697282.Mettu_1426	1.151e-67	243.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,1XGZ4@135618|Methylococcales	135618|Methylococcales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_545053_6	671143.DAMO_3124	6.969e-56	212.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,SpoIIE,sCache_3_2
SRR25158380_k127_545053_10	411684.HPDFL43_13867	1.022e-09	61.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,43QQ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR25158380_k127_545053_7	765420.OSCT_0546	1.137e-38	167.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_545053_5	266117.Rxyl_0481	1.165e-62	224.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4CQ98@84995|Rubrobacteria	84995|Rubrobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158380_k127_545053_4	981369.JQMJ01000004_gene452	1.285e-64	230.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,2NIHT@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158380_k127_545053_0	1380355.JNIJ01000009_gene1803	1.249e-173	570.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3JUQU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
SRR25158380_k127_545053_2	1033730.CAHG01000014_gene1741	6.401e-68	243.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4DN4H@85009|Propionibacteriales	201174|Actinobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobA	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SRR25158380_k127_545084_2	861299.J421_5992	6.196e-46	169.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_545084_0	861299.J421_5993	5.15e-115	385.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158380_k127_545084_1	861299.J421_5989	3.144e-73	257.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_545084_3	861299.J421_5988	2.55e-09	61.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158380_k127_560498_0	861299.J421_3441	1.678e-189	608.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158380_k127_560498_1	379066.GAU_1870	5.723e-105	355.0	COG0190@1|root,COG0190@2|Bacteria,1ZSVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158380_k127_560498_3	379066.GAU_1869	1.675e-35	149.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158380_k127_560498_2	379066.GAU_1869	5.269e-41	157.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158380_k127_563657_1	861299.J421_1936	6.16e-55	199.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158380_k127_563657_0	713586.KB900536_gene2448	1.477e-82	284.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,1S7AD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_563657_2	1337936.IJ00_00910	2.52e-14	86.0	2EFPZ@1|root,339G0@2|Bacteria,1GCBN@1117|Cyanobacteria,1HIZK@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_587554_0	1379270.AUXF01000005_gene699	1.06e-213	680.0	COG1200@1|root,COG1200@2|Bacteria,1ZT3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158380_k127_587554_4	1306990.BARG01000042_gene4905	2.551e-19	102.0	COG1520@1|root,COG4249@1|root,COG1520@2|Bacteria,COG4249@2|Bacteria,2IAM3@201174|Actinobacteria	201174|Actinobacteria	U	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SRR25158380_k127_587554_1	379066.GAU_1447	4.934e-186	590.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_587554_2	861299.J421_3092	1.021e-75	261.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRR25158380_k127_587554_3	861299.J421_3093	1.295e-42	165.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158380_k127_608098_2	379066.GAU_1764	4.274e-56	199.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158380_k127_608098_3	1379270.AUXF01000006_gene129	5.764e-32	130.0	COG0184@1|root,COG0184@2|Bacteria,1ZU0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158380_k127_608098_4	980584.AFPB01000174_gene1596	2.729e-19	94.0	COG0399@1|root,COG0399@2|Bacteria,4P9JE@976|Bacteroidetes,1IGJK@117743|Flavobacteriia,4078G@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158380_k127_608098_1	1158318.ATXC01000001_gene1406	2.086e-66	254.0	COG0750@1|root,COG0750@2|Bacteria,2G3QY@200783|Aquificae	200783|Aquificae	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158380_k127_608098_0	1382304.JNIL01000001_gene573	2.537e-104	354.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,2788P@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158380_k127_608098_5	1444310.JANV01000086_gene110	8.595e-18	85.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,1ZBWF@1386|Bacillus	91061|Bacilli	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
SRR25158380_k127_608607_2	663932.KB902575_gene2252	2.949e-38	148.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2JQDQ@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158380_k127_608607_0	861299.J421_3436	1.452e-240	764.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158380_k127_608607_1	861299.J421_3436	2.14e-53	192.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158380_k127_611697_1	1379270.AUXF01000001_gene2805	6.932e-100	339.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158380_k127_611697_4	1379270.AUXF01000001_gene2804	6.926e-34	149.0	COG1853@1|root,COG1853@2|Bacteria,1ZTVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158380_k127_611697_3	1379270.AUXF01000001_gene2803	4.789e-41	168.0	COG0500@1|root,COG2226@2|Bacteria,1ZTP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_611697_2	861299.J421_4184	2.245e-46	172.0	COG2867@1|root,COG2867@2|Bacteria,1ZTVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158380_k127_611697_0	861299.J421_4185	5.6e-173	559.0	COG0304@1|root,COG0304@2|Bacteria,1ZTE1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158380_k127_645830_0	379066.GAU_1225	5.995e-156	519.0	COG1629@1|root,COG4771@2|Bacteria,1ZTMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158380_k127_645830_1	378806.STAUR_7451	1.411e-08	56.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2Z3F9@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
SRR25158380_k127_646534_3	1279009.ADICEAN_00812	3.205e-52	201.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,47KJ1@768503|Cytophagia	976|Bacteroidetes	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
SRR25158380_k127_646534_7	1183438.GKIL_0790	0.0006993	48.0	COG3655@1|root,COG3655@2|Bacteria,1GATR@1117|Cyanobacteria	1117|Cyanobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SRR25158380_k127_646534_2	479434.Sthe_0472	1.87e-54	198.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi,27YAF@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158380_k127_646534_4	562970.Btus_1455	3.354e-43	166.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158380_k127_646534_1	861299.J421_3824	1.089e-89	301.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158380_k127_646534_6	1122622.ATWJ01000007_gene1839	2.218e-23	109.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4FGPM@85021|Intrasporangiaceae	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158380_k127_646534_5	1410625.JHWK01000003_gene1617	8.768e-24	104.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,27NX3@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein S16	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158380_k127_646534_0	861299.J421_3827	1.144e-162	520.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158380_k127_651155_3	1121927.GOHSU_13_00310	8.702e-05	45.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4GESD@85026|Gordoniaceae	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158380_k127_651155_1	1379270.AUXF01000005_gene495	8.016e-61	219.0	COG0664@1|root,COG0664@2|Bacteria,1ZTHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158380_k127_651155_0	460265.Mnod_1367	8.106e-64	230.0	COG0745@1|root,COG1235@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,COG2203@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,1JWZZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	KT	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158380_k127_651155_2	1192034.CAP_8000	3.811e-34	139.0	28I3N@1|root,2Z87C@2|Bacteria,1R8BJ@1224|Proteobacteria,437XX@68525|delta/epsilon subdivisions,2X37T@28221|Deltaproteobacteria,2YURB@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
SRR25158380_k127_667376_4	861299.J421_5587	3.053e-45	176.0	COG0746@1|root,COG0746@2|Bacteria,1ZU64@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158380_k127_667376_5	935840.JAEQ01000017_gene1900	2.094e-21	102.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,43JQ9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
SRR25158380_k127_667376_2	479434.Sthe_1113	2.112e-95	334.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi,27XRV@189775|Thermomicrobia	189775|Thermomicrobia	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158380_k127_667376_0	861299.J421_4481	5.315e-99	334.0	COG0501@1|root,COG0501@2|Bacteria,1ZSNK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158380_k127_667376_1	316274.Haur_0016	8.92e-97	325.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158380_k127_667376_3	1121015.N789_02130	6.582e-91	321.0	COG0457@1|root,COG0793@1|root,COG0457@2|Bacteria,COG0793@2|Bacteria,1PW54@1224|Proteobacteria,1SXHB@1236|Gammaproteobacteria,1X8XJ@135614|Xanthomonadales	135614|Xanthomonadales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_71265_2	935845.JADQ01000007_gene1676	4.708e-35	151.0	COG0329@1|root,COG0329@2|Bacteria,1U034@1239|Firmicutes,4I9D8@91061|Bacilli,271D2@186822|Paenibacillaceae	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
SRR25158380_k127_71265_1	861299.J421_3632	9.088e-58	221.0	COG2159@1|root,COG2159@2|Bacteria,1ZTHS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_71265_0	861299.J421_3633	6.893e-113	369.0	COG2159@1|root,COG2159@2|Bacteria,1ZSXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158380_k127_71265_3	861299.J421_3634	4.983e-24	107.0	COG0001@1|root,COG0001@2|Bacteria,1ZSWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_72615_1	1232437.KL662027_gene2835	0.0006645	53.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MN86@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
SRR25158380_k127_72615_0	861299.J421_3065	1.803e-37	151.0	2DUTE@1|root,33S5W@2|Bacteria,1ZSMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_736827_1	342610.Patl_1191	6.479e-10	63.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,2Q3P7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_736827_0	1121920.AUAU01000012_gene2710	1.047e-28	130.0	COG0438@1|root,COG0438@2|Bacteria,3Y7QU@57723|Acidobacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_736827_2	697281.Mahau_1506	1.12e-06	60.0	COG4641@1|root,COG4641@2|Bacteria,1V2W1@1239|Firmicutes,24GPM@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
SRR25158380_k127_736827_3	1267211.KI669560_gene205	6.211e-06	52.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,1IPES@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
SRR25158380_k127_73855_0	1298863.AUEP01000003_gene3076	3.668e-47	179.0	2B7FS@1|root,320JK@2|Bacteria,2H4AH@201174|Actinobacteria,4DUBC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_73855_2	1124780.ANNU01000023_gene3209	4.386e-11	70.0	2DNSC@1|root,32YWT@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158380_k127_73855_1	1121438.JNJA01000004_gene789	8.215e-12	75.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria,2M89Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_749622_1	861299.J421_0460	3.032e-88	307.0	COG1807@1|root,COG1807@2|Bacteria,1ZUFB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_749622_0	479434.Sthe_0848	2.528e-98	336.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	atrB	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_754696_1	861299.J421_6234	3.106e-81	293.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_6234|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_754696_3	1121938.AUDY01000008_gene1232	3.287e-58	216.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,3NEZW@45667|Halobacillus	91061|Bacilli	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0019752,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901564	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158380_k127_754696_8	861299.J421_2670	7.865e-05	48.0	296V5@1|root,2ZU41@2|Bacteria,1ZU78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_754696_0	861299.J421_2672	2.395e-114	390.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_754696_6	1379270.AUXF01000005_gene516	3.807e-46	176.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158380_k127_754696_2	861299.J421_2674	9.651e-62	221.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
SRR25158380_k127_754696_4	1125863.JAFN01000001_gene535	3.034e-54	204.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_756436_1	926550.CLDAP_15440	2.407e-10	64.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,Flg_new,GPDPase_memb
SRR25158380_k127_756436_3	67315.JOBD01000012_gene655	1.61e-05	54.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158380_k127_756436_0	1122622.ATWJ01000007_gene1610	7.656e-94	326.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FEQS@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158380_k127_772664_2	1227349.C170_08805	1.291e-13	79.0	COG1309@1|root,COG1309@2|Bacteria,1V95E@1239|Firmicutes,4HJIZ@91061|Bacilli,26XCP@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K22106	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_10,TetR_N
SRR25158380_k127_772664_0	861299.J421_2400	5.898e-143	464.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158380_k127_772664_1	861299.J421_3035	8.053e-41	168.0	COG0526@1|root,COG0526@2|Bacteria,1ZU4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
SRR25158380_k127_772664_3	502025.Hoch_5370	3.047e-06	55.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,42S2Q@68525|delta/epsilon subdivisions,2WNSG@28221|Deltaproteobacteria,2YX6N@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SRR25158380_k127_774235_0	861299.J421_3155	2.414e-165	537.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158380_k127_774235_1	861299.J421_3154	5.615e-35	153.0	COG4783@1|root,COG4783@2|Bacteria,1ZT36@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD,SH3_4
SRR25158380_k127_782167_1	926549.KI421517_gene113	5.623e-95	319.0	COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,47MHW@768503|Cytophagia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_782167_0	448385.sce2596	2.198e-97	330.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,42YQ0@68525|delta/epsilon subdivisions,2WTRV@28221|Deltaproteobacteria,2YUFX@29|Myxococcales	28221|Deltaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_803747_2	330214.NIDE4102	5.669e-11	73.0	COG1989@1|root,COG1989@2|Bacteria,3J0SK@40117|Nitrospirae	40117|Nitrospirae	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158380_k127_803747_1	861299.J421_3830	1.462e-68	258.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_803747_3	1095747.HMPREF1049_1015	5.416e-09	70.0	COG4399@1|root,COG4399@2|Bacteria,37A4K@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158380_k127_803747_0	861299.J421_3829	5.041e-81	277.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158380_k127_811162_2	1254432.SCE1572_52190	9.923e-71	247.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158380_k127_811162_0	379066.GAU_2427	3.11e-264	827.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158380_k127_811162_1	861299.J421_3894	2.292e-156	506.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_811162_3	379066.GAU_2430	1.148e-60	216.0	COG3437@1|root,COG3437@2|Bacteria,1ZSX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
SRR25158380_k127_811733_0	379066.GAU_2917	7.852e-152	484.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
SRR25158380_k127_811733_1	765420.OSCT_0396	6.672e-86	292.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158380_k127_811733_2	861299.J421_1280	1.085e-10	74.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
SRR25158380_k127_815945_3	696281.Desru_1900	2.1e-26	113.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,262H0@186807|Peptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158380_k127_815945_2	1048834.TC41_1376	3.774e-54	206.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,278AP@186823|Alicyclobacillaceae	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
SRR25158380_k127_815945_1	861299.J421_3191	9.397e-91	309.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158380_k127_815945_0	1379270.AUXF01000005_gene826	1.093e-101	356.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158380_k127_81769_0	861208.AGROH133_12807	4.93e-121	416.0	COG0784@1|root,COG2461@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2461@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B880@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SRR25158380_k127_81769_1	479433.Caci_1425	1.08e-78	267.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_822281_2	1379270.AUXF01000001_gene2253	5.934e-17	85.0	COG2234@1|root,COG2234@2|Bacteria,1ZSUA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_822281_0	861299.J421_0308	5.943e-72	248.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_824638_1	357808.RoseRS_3729	1.342e-32	134.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_824638_0	861299.J421_2379	2.081e-138	450.0	COG1804@1|root,COG1804@2|Bacteria,1ZT8E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158380_k127_824638_2	1232437.KL662006_gene4425	0.0001404	53.0	28V7D@1|root,2ZHAI@2|Bacteria,1RA29@1224|Proteobacteria,42R9H@68525|delta/epsilon subdivisions,2WN1D@28221|Deltaproteobacteria,2MJN2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SRR25158380_k127_829875_3	379066.GAU_0007	1.071e-16	86.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158380_k127_829875_0	379066.GAU_0008	1.78e-96	324.0	COG0515@1|root,COG0515@2|Bacteria,1ZT9E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158380_k127_829875_2	861299.J421_1148	3.234e-59	222.0	2DTII@1|root,33KI8@2|Bacteria,1ZT3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_829875_1	861299.J421_1151	1.987e-90	302.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158380_k127_833307_3	861299.J421_0561	1.59e-27	122.0	2CDZB@1|root,3340J@2|Bacteria,1ZU24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_833307_0	861299.J421_0867	1.462e-160	538.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_0867|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158380_k127_833307_5	1123059.KB823014_gene36	2.779e-05	55.0	29A93@1|root,33K0N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
SRR25158380_k127_833307_4	1121948.AUAC01000008_gene786	3.318e-17	92.0	2CK46@1|root,337US@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
SRR25158380_k127_833307_2	1380394.JADL01000001_gene2572	2.39e-70	250.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,2JSQW@204441|Rhodospirillales	204441|Rhodospirillales	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158380_k127_833307_1	1121406.JAEX01000002_gene760	2.234e-96	321.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,42MZ8@68525|delta/epsilon subdivisions,2WMM3@28221|Deltaproteobacteria,2MG24@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_835230_3	546414.Deide_12150	2.518e-14	75.0	COG0821@1|root,COG0821@2|Bacteria,1WJ94@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158380_k127_835230_0	903818.KI912268_gene936	3.144e-102	345.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158380_k127_835230_1	1192034.CAP_6426	2.922e-90	308.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZAP@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_846982_1	379066.GAU_3081	9.484e-58	206.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1ZSQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158380_k127_846982_3	1121382.JQKG01000008_gene969	2.325e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,1WN5A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_846982_0	290397.Adeh_1417	1.358e-207	663.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_846982_2	118005.AWNK01000003_gene2461	1.981e-39	150.0	COG0780@1|root,COG0780@2|Bacteria	2|Bacteria	G	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158380_k127_846982_4	1380390.JIAT01000009_gene1231	5.921e-19	90.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158380_k127_859749_0	1283299.AUKG01000002_gene4559	4.987e-92	313.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158380_k127_859749_1	1340493.JNIF01000004_gene751	1.861e-21	109.0	COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158380_k127_871533_0	379066.GAU_1980	5.218e-65	237.0	COG0860@1|root,COG0860@2|Bacteria,1ZSUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRR25158380_k127_871533_1	861299.J421_3584	1.309e-54	196.0	COG0691@1|root,COG0691@2|Bacteria,1ZTQN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158380_k127_871533_2	1382359.JIAL01000001_gene1431	8.817e-17	81.0	COG0476@1|root,COG0476@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRR25158380_k127_877465_3	1121324.CLIT_2c03230	1.367e-64	235.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SRR25158380_k127_877465_4	357808.RoseRS_1234	7.317e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158380_k127_877465_5	1120968.AUBX01000009_gene641	9.482e-19	102.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158380_k127_877465_0	1168065.DOK_07994	8.119e-193	629.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RSC3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD binding domain	-	-	1.3.1.72	ko:K09828	ko00100,ko01100,ko01110,map00100,map01100,map01110	M00101	R01457,R03689,R05703,R07488,R07493,R07498,R07499,R07507,R11096	RC00522,RC01887,RC02419	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,Acetyltransf_1,FAD_binding_4,Methyltransf_11
SRR25158380_k127_877465_1	526227.Mesil_2861	8.373e-142	466.0	COG0446@1|root,COG0446@2|Bacteria,1WM48@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C,Rieske
SRR25158380_k127_877465_2	1089550.ATTH01000001_gene1363	8.889e-78	267.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJZQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158380_k127_878238_1	861299.J421_3527	3.293e-166	528.0	COG0468@1|root,COG0468@2|Bacteria,1ZT78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158380_k127_878238_2	1142394.PSMK_32000	6.648e-08	65.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158380_k127_878238_0	626887.J057_23620	7.04e-225	736.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158380_k127_885920_2	1146883.BLASA_3073	6.683e-62	218.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4ES0K@85013|Frankiales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274,ko:K15408	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1,Cyt_c_ox_IV
SRR25158380_k127_885920_1	1041147.AUFB01000001_gene4594	1.673e-86	301.0	COG1622@1|root,COG3474@1|root,COG1622@2|Bacteria,COG3474@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRS5@28211|Alphaproteobacteria,4BBNX@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
SRR25158380_k127_885920_4	1121943.KB900010_gene2734	1.851e-21	108.0	COG2010@1|root,COG2010@2|Bacteria,1RHET@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
SRR25158380_k127_885920_0	754035.Mesau_04079	3.239e-102	340.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,43JJK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
SRR25158380_k127_885920_3	876269.ARWA01000001_gene1479	9.439e-26	108.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3NCBP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
SRR25158380_k127_886424_0	1210884.HG799466_gene12816	6.723e-111	377.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_891552_3	861299.J421_2015	2.327e-11	76.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158380_k127_891552_2	1379270.AUXF01000001_gene2307	2.344e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,1ZTWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158380_k127_891552_0	1379270.AUXF01000001_gene2025	1.557e-139	464.0	COG2223@1|root,COG2223@2|Bacteria,1ZT8I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_891552_1	861299.J421_1236	9.699e-73	251.0	COG0488@1|root,COG0488@2|Bacteria,1ZSV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158380_k127_904314_1	661478.OP10G_3363	2.539e-69	246.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	Cytochrome_CBB3,DUF1863,PQQ,PQQ_2,PQQ_3,Pkinase
SRR25158380_k127_904314_2	1184267.A11Q_1050	1.201e-63	231.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2MTW3@213481|Bdellovibrionales,2WKTX@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158380_k127_904314_4	258533.BN977_06082	1.671e-05	57.0	COG4307@1|root,COG4307@2|Bacteria,2GKD6@201174|Actinobacteria,234DW@1762|Mycobacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
SRR25158380_k127_904314_0	886293.Sinac_4898	3.901e-247	779.0	COG1233@1|root,COG1233@2|Bacteria,2IX17@203682|Planctomycetes	203682|Planctomycetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158380_k127_904314_3	861299.J421_0433	6.624e-35	136.0	COG0013@1|root,COG0013@2|Bacteria,1ZT0G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158380_k127_911436_2	1122138.AQUZ01000019_gene8186	2.202e-73	258.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158380_k127_911436_0	861299.J421_3164	7.578e-285	883.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158380_k127_911436_3	1379270.AUXF01000005_gene789	5.569e-35	136.0	COG0234@1|root,COG0234@2|Bacteria,1ZTZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158380_k127_911436_1	1379698.RBG1_1C00001G0983	5.774e-95	326.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158380_k127_92536_2	983920.Y88_1718	5.868e-08	58.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,2K9V3@204457|Sphingomonadales	204457|Sphingomonadales	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH,PBP
SRR25158380_k127_92536_1	1089549.AZUQ01000001_gene166	1.722e-56	207.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4EYD4@85014|Glycomycetales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158380_k127_92536_0	1502850.FG91_03868	1.838e-58	209.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,2UCNR@28211|Alphaproteobacteria,2K0VY@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158380_k127_926929_0	861299.J421_3636	1.691e-58	219.0	2AEF2@1|root,314A1@2|Bacteria,1ZSNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
SRR25158380_k127_926929_1	1128421.JAGA01000002_gene806	8.949e-58	219.0	COG2605@1|root,COG2605@2|Bacteria	1128421.JAGA01000002_gene806|-	G	GHMP kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_926929_2	1379270.AUXF01000003_gene3815	5.105e-23	104.0	COG0747@1|root,COG0747@2|Bacteria,1ZTAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158380_k127_92979_3	365044.Pnap_3007	2.41e-117	383.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VMVP@28216|Betaproteobacteria,4AJ78@80864|Comamonadaceae	28216|Betaproteobacteria	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
SRR25158380_k127_92979_4	1366050.N234_08070	4.493e-46	175.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2WESG@28216|Betaproteobacteria,1K748@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K06867,ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_4,Ank_5
SRR25158380_k127_92979_5	379066.GAU_2567	2.101e-35	147.0	COG2755@1|root,COG2755@2|Bacteria,1ZU6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_92979_1	861299.J421_3598	1.224e-163	536.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158380_k127_92979_0	861299.J421_3597	3.582e-176	558.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158380_k127_92979_2	278963.ATWD01000001_gene3203	1.266e-118	397.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158380_k127_934625_2	1382356.JQMP01000003_gene1834	3.077e-66	255.0	COG3876@1|root,COG3876@2|Bacteria,2G655@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158380_k127_934625_0	861299.J421_3604	6.561e-126	436.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158380_k127_934625_1	251221.35214024	8.312e-80	297.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158380_k127_950212_3	861299.J421_3842	2.748e-17	88.0	COG5492@1|root,COG5492@2|Bacteria,1ZSN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_950212_2	1379270.AUXF01000003_gene3563	8.402e-31	130.0	2ES4T@1|root,33JPM@2|Bacteria,1ZU4W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_950212_0	379066.GAU_2360	2.043e-98	352.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158380_k127_950212_1	1379270.AUXF01000003_gene3568	2.682e-89	312.0	COG0745@1|root,COG0745@2|Bacteria,1ZTC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_950212_4	1379270.AUXF01000001_gene2712	7.061e-12	72.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158380_k127_958699_5	700598.Niako_2262	5.215e-09	69.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1ISGX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_958699_0	290397.Adeh_0450	8.993e-270	849.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
SRR25158380_k127_958699_1	1089550.ATTH01000001_gene237	4.836e-170	557.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158380_k127_958699_2	861299.J421_3849	2.058e-110	381.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_958699_3	1265313.HRUBRA_00432	1.109e-66	246.0	COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,1T0QH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG4257 Streptogramin lyase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158380_k127_964486_1	379066.GAU_0468	1.626e-42	161.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158380_k127_964486_2	861299.J421_2370	9.412e-21	102.0	2F95J@1|root,341H1@2|Bacteria,1ZTZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_964486_0	497964.CfE428DRAFT_4290	2.116e-156	503.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_96944_1	861299.J421_3000	6.597e-43	158.0	COG0183@1|root,COG0183@2|Bacteria,1ZTGX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_96944_3	546414.Deide_19460	3.497e-25	115.0	COG1268@1|root,COG1268@2|Bacteria,1WJ9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158380_k127_96944_2	861299.J421_3001	2.618e-27	124.0	COG1266@1|root,COG1266@2|Bacteria,1ZTXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158380_k127_96944_0	1379270.AUXF01000005_gene596	5.224e-104	358.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_97833_1	861299.J421_1842	5.528e-54	202.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	litR	-	2.3.3.1	ko:K01647,ko:K22491	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158380_k127_97833_0	903818.KI912268_gene1318	8.405e-183	594.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158380_k127_97833_2	1297742.A176_00391	2.104e-32	146.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2YUE6@29|Myxococcales	28221|Deltaproteobacteria	L	Deoxyribodipyrimidine photo-lyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158380_k127_989528_1	34007.IT40_09780	4.591e-08	61.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,2TUFY@28211|Alphaproteobacteria,2PVHK@265|Paracoccus	28211|Alphaproteobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158380_k127_989528_0	521096.Tpau_2757	1.962e-14	84.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158380_k127_992423_0	264732.Moth_2312	1.749e-152	508.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,42FDP@68295|Thermoanaerobacterales	186801|Clostridia	C	Formate dehydrogenase alpha subunit	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158380_k127_993349_5	861299.J421_2181	6.098e-08	57.0	COG4995@1|root,COG4995@2|Bacteria,1ZUKA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158380_k127_993349_2	861299.J421_1214	2.317e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,1ZV5F@142182|Gemmatimonadetes	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	PD40,PQQ_2,Sigma70_r2,Sigma70_r4_2,WD40
SRR25158380_k127_993349_0	379066.GAU_2797	0.0	1020.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158380_k127_993349_1	290397.Adeh_2670	2.854e-78	267.0	2D579@1|root,32QJ3@2|Bacteria,1NV2H@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_993349_3	886293.Sinac_4749	2.259e-36	148.0	COG1167@1|root,COG1167@2|Bacteria,2IYEU@203682|Planctomycetes	203682|Planctomycetes	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158380_k127_995301_3	861299.J421_3532	5.003e-46	182.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158380_k127_995301_0	1120973.AQXL01000127_gene2738	1.064e-187	596.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,277WZ@186823|Alicyclobacillaceae	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158380_k127_995301_1	1379270.AUXF01000006_gene35	9.682e-159	510.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158380_k127_995301_6	1379270.AUXF01000006_gene34	2.204e-32	139.0	COG0511@1|root,COG0511@2|Bacteria,1ZTR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158380_k127_995301_2	1379270.AUXF01000006_gene33	2.717e-95	323.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158380_k127_995301_4	1121385.AQXW01000004_gene2450	6.187e-45	166.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,1ZWS1@145357|Dermacoccaceae	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II,PTS_EIIB
SRR25158380_k127_995301_7	1379698.RBG1_1C00001G1748	1.705e-09	70.0	COG0457@1|root,COG0457@2|Bacteria,2NS1B@2323|unclassified Bacteria	2|Bacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_995301_5	1379270.AUXF01000006_gene30	8.723e-40	160.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
SRR25158380_k127_997009_2	1144275.COCOR_00398	9.211e-58	203.0	COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,2YYT4@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR25158380_k127_997009_4	861299.J421_2828	2.364e-41	163.0	COG0735@1|root,COG0735@2|Bacteria,1ZTN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158380_k127_997009_1	379066.GAU_0930	1.445e-76	271.0	COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158380_k127_997009_3	1173022.Cri9333_2806	1.337e-47	181.0	COG2340@1|root,COG2340@2|Bacteria,1G68A@1117|Cyanobacteria,1HBHS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158380_k127_997009_0	379066.GAU_0931	7.265e-78	266.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
## 2003 queries scanned
## Total time (seconds): 2.7543692588806152
## Rate: 727.21 q/s