## Sun Dec 14 23:26:34 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158380_bin.7.fa -m mmseqs --itype genome -o SRR25158380_bin.7 --output_dir /data/result/bins/wyx/egg/SRR25158380_bin.7 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158380_k127_1000_3	439481.Aboo_0904	1.281e-135	441.0	COG1228@1|root,arCOG00696@2157|Archaea,2XVAU@28890|Euryarchaeota,3F2Z2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_1000_5	1121289.JHVL01000024_gene123	4.061e-57	203.0	COG0717@1|root,COG0717@2|Bacteria,1V1BE@1239|Firmicutes,24A3M@186801|Clostridia,36G9F@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
SRR25158380_k127_1000_2	1459636.NTE_01058	4.306e-153	496.0	arCOG04732@1|root,arCOG04732@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1000_1	1459636.NTE_01048	1.033e-174	561.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_1000_4	1459636.NTE_02137	6.615e-95	316.0	COG1945@1|root,arCOG04490@2157|Archaea,41SPZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
SRR25158380_k127_1000_6	688269.Theth_1666	3.485e-27	116.0	COG1656@1|root,COG1656@2|Bacteria,2GDIT@200918|Thermotogae	200918|Thermotogae	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
SRR25158380_k127_1000_0	1459636.NTE_01231	0.0	1078.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158380_k127_1012181_0	1459636.NTE_02786	3.805e-30	119.0	COG4275@1|root,arCOG10427@2157|Archaea	2157|Archaea	S	Chromate resistance	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158380_k127_1012181_3	1116369.KB890024_gene4140	4.552e-06	54.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U35E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158380_k127_1012181_2	373994.Riv7116_5809	2.188e-11	73.0	COG0515@1|root,COG5435@1|root,COG0515@2|Bacteria,COG5435@2|Bacteria,1GHWT@1117|Cyanobacteria,1HR2V@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,PsbP
SRR25158380_k127_1012181_1	1459636.NTE_02627	2.863e-21	96.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_1046137_1	755178.Cyan10605_0904	9.077e-54	193.0	COG3542@1|root,COG3542@2|Bacteria,1G6JR@1117|Cyanobacteria	1117|Cyanobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158380_k127_1046137_2	258594.RPA4724	1.891e-25	114.0	COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,3JRPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158380_k127_1046137_0	1459636.NTE_01927	7.82e-66	235.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158380_k127_1102459_19	436308.Nmar_1633	6.041e-72	247.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158380_k127_1102459_4	1459636.NTE_00103	1.255e-178	582.0	COG0550@1|root,arCOG01527@2157|Archaea,41TBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	-
SRR25158380_k127_1102459_3	1459636.NTE_02857	2.835e-206	645.0	COG1980@1|root,arCOG04180@2157|Archaea,41S67@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
SRR25158380_k127_1102459_20	1459636.NTE_02858	1.677e-69	242.0	COG0149@1|root,arCOG01087@2157|Archaea,41SHT@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158380_k127_1102459_31	1459636.NTE_01532	2.517e-22	99.0	arCOG08750@1|root,arCOG08750@2157|Archaea	1459636.NTE_01532|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1102459_6	1229909.NSED_09015	1.172e-158	525.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158380_k127_1102459_33	1459636.NTE_02729	1.312e-09	64.0	COG0347@1|root,arCOG02305@2157|Archaea,41TB5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158380_k127_1102459_10	1459636.NTE_02404	2.416e-113	374.0	COG0608@1|root,arCOG00424@2157|Archaea,41SE2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
SRR25158380_k127_1102459_12	1459636.NTE_00119	1.624e-112	364.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	2157|Archaea	S	Ferritin-like domain	dps	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158380_k127_1102459_16	1459636.NTE_03124	3.613e-82	286.0	COG0524@1|root,arCOG00014@2157|Archaea	2157|Archaea	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB,Regulator_TrmB,TrmB
SRR25158380_k127_1102459_22	589924.Ferp_2384	2.727e-62	224.0	COG1004@1|root,arCOG00253@2157|Archaea,2XTQY@28890|Euryarchaeota,246SR@183980|Archaeoglobi	183980|Archaeoglobi	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158380_k127_1102459_15	1128421.JAGA01000003_gene3109	1.358e-96	333.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158380_k127_1102459_32	1459636.NTE_00679	8.836e-21	93.0	arCOG05330@1|root,arCOG05330@2157|Archaea,41SUC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1102459_1	1459636.NTE_00680	6.205e-270	844.0	COG0441@1|root,arCOG00401@2157|Archaea,41S9K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
SRR25158380_k127_1102459_37	1123320.KB889667_gene2963	0.0003534	53.0	COG2730@1|root,COG2730@2|Bacteria,2HQAQ@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
SRR25158380_k127_1102459_34	1459636.NTE_00200	1.224e-06	55.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1102459_18	1459636.NTE_01932	2.513e-76	272.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_1102459_13	1459636.NTE_01730	1.047e-105	361.0	arCOG04615@1|root,arCOG04615@2157|Archaea	2157|Archaea	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_1102459_17	1459636.NTE_00665	2.242e-78	270.0	COG0463@1|root,arCOG00894@2157|Archaea,41SAS@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158380_k127_1102459_0	1459636.NTE_03123	6.74e-278	863.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
SRR25158380_k127_1102459_24	1459636.NTE_03122	2.219e-51	184.0	COG5496@1|root,arCOG04331@2157|Archaea	2157|Archaea	S	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158380_k127_1102459_2	1229909.NSED_02815	1.126e-223	701.0	COG0043@1|root,arCOG01671@2157|Archaea,41S94@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158380_k127_1102459_27	1459636.NTE_03007	2.061e-36	144.0	COG0494@1|root,arCOG01072@2157|Archaea,41STX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158380_k127_1102459_21	1459636.NTE_02998	1.887e-63	226.0	COG0685@1|root,arCOG00475@2157|Archaea,41SNK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	cytochrome-c peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1102459_11	1459636.NTE_02997	1.294e-112	368.0	COG1116@1|root,arCOG00193@2157|Archaea,41S6Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158380_k127_1102459_9	1459636.NTE_00628	3.191e-115	384.0	COG1867@1|root,arCOG01219@2157|Archaea,41SAG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	-	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
SRR25158380_k127_1102459_23	1459636.NTE_00626	3.001e-55	200.0	COG0164@1|root,arCOG04121@2157|Archaea,41SK9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158380_k127_1102459_14	1459636.NTE_00625	8.96e-100	331.0	COG0513@1|root,arCOG00078@2157|Archaea,41SM2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
SRR25158380_k127_1102459_8	1459636.NTE_00624	2.68e-126	417.0	COG1498@1|root,arCOG01923@2157|Archaea,41SY9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	NOSIC (NUC001) domain	-	-	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
SRR25158380_k127_1102459_25	1459636.NTE_01618	8.932e-48	175.0	COG1310@1|root,arCOG01139@2157|Archaea,41SQ7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158380_k127_1102459_26	1459636.NTE_01615	1.505e-37	144.0	arCOG08751@1|root,arCOG08751@2157|Archaea,41SS7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1102459_30	868131.MSWAN_1251	4.65e-26	119.0	COG0457@1|root,arCOG00127@1|root,arCOG05195@1|root,arCOG00127@2157|Archaea,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG05195@2157|Archaea,2XUNW@28890|Euryarchaeota,23PX5@183925|Methanobacteria	28890|Euryarchaeota	S	Tetratricopeptide TPR-1	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158380_k127_1102459_5	1459636.NTE_00771	5.298e-168	542.0	COG1173@1|root,arCOG00749@2157|Archaea,41SFE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158380_k127_1102459_7	1459636.NTE_00772	1.473e-147	474.0	COG0601@1|root,arCOG00751@2157|Archaea,41S7B@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158380_k127_1118_0	1459636.NTE_01596	1.654e-13	76.0	arCOG08725@1|root,arCOG08725@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1118_1	1459636.NTE_02333	4.746e-11	66.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1142022_2	641112.ACOK01000116_gene2664	8.66e-11	70.0	COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,2494B@186801|Clostridia,3WHQJ@541000|Ruminococcaceae	186801|Clostridia	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF676,PGAP1
SRR25158380_k127_1142022_0	1459636.NTE_01608	1.012e-100	330.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
SRR25158380_k127_1142022_1	436308.Nmar_1695	8.249e-51	183.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158380_k127_1151880_0	1459636.NTE_01386	3.117e-29	122.0	COG0350@1|root,arCOG02724@2157|Archaea,41SR8@651137|Thaumarchaeota	651137|Thaumarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158380_k127_1154533_3	391623.TERMP_01864	1.668e-26	127.0	COG0419@1|root,arCOG00368@2157|Archaea,2XTC7@28890|Euryarchaeota,244YZ@183968|Thermococci	183968|Thermococci	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_21,Rad50_zn_hook
SRR25158380_k127_1154533_4	1379698.RBG1_1C00001G1268	1.028e-22	112.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158380_k127_1154533_0	481448.Minf_0852	6.623e-187	603.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR25158380_k127_1154533_1	481448.Minf_0851	8.503e-109	364.0	2C6Q3@1|root,2Z7T4@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR25158380_k127_1154533_8	192952.MM_2399	3.002e-05	48.0	COG0225@1|root,arCOG02816@2157|Archaea,2XWKA@28890|Euryarchaeota,2N9M6@224756|Methanomicrobia	224756|Methanomicrobia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158380_k127_1154533_5	1370122.JHXQ01000002_gene2851	1.243e-21	100.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BCXZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase2,He_PIG,HemolysinCabind
SRR25158380_k127_1154533_6	436308.Nmar_0853	7.758e-16	83.0	COG0346@1|root,arCOG02708@2157|Archaea,41SU3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158380_k127_1154533_2	1459636.NTE_02871	8.014e-27	113.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
SRR25158380_k127_1154828_0	1459636.NTE_02810	1.074e-117	383.0	COG0330@1|root,arCOG01915@2157|Archaea	2157|Archaea	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_1156663_3	1459636.NTE_02002	2.586e-35	138.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1156663_1	1229909.NSED_00250	6.395e-50	183.0	arCOG08723@1|root,arCOG08723@2157|Archaea,41SPX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1156663_0	1459636.NTE_02315	7.459e-118	389.0	COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
SRR25158380_k127_1156663_2	1280686.AUKE01000018_gene2848	1.255e-44	171.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,4BX1F@830|Butyrivibrio	186801|Clostridia	T	Protein phosphatase 2C	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158380_k127_1156663_4	1459636.NTE_02314	5.342e-28	116.0	COG1324@1|root,arCOG04231@2157|Archaea,41SR4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158380_k127_1185125_1	1459636.NTE_03208	1.917e-92	306.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_1185125_0	1459636.NTE_03207	2.968e-198	626.0	COG0019@1|root,arCOG02268@2157|Archaea	2157|Archaea	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.17,4.1.1.20,4.1.1.96	ko:K01581,ko:K01586,ko:K13747	ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230	M00016,M00134,M00525,M00526,M00527	R00451,R00670,R09081,R09082	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2177	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158380_k127_1185125_5	1121468.AUBR01000003_gene635	7.67e-23	101.0	COG1254@1|root,COG1254@2|Bacteria,1UEN2@1239|Firmicutes,25JM5@186801|Clostridia,42HJX@68295|Thermoanaerobacterales	186801|Clostridia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158380_k127_1185125_6	1459636.NTE_03205	3.003e-18	88.0	arCOG10515@1|root,arCOG10515@2157|Archaea,41TAP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1185125_4	1459636.NTE_01296	5.403e-43	158.0	COG2146@1|root,arCOG02852@2157|Archaea,41SSE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158380_k127_1185125_7	1459636.NTE_03100	8.603e-13	70.0	COG1872@1|root,arCOG04058@2157|Archaea,41TAX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158380_k127_1185125_2	944481.JAFP01000001_gene373	1.029e-65	226.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2M75M@213113|Desulfurellales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158380_k127_1186432_1	1459636.NTE_00742	1.798e-73	252.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_1186432_2	1459636.NTE_02332	9.794e-19	96.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1186432_0	1459636.NTE_03163	3.557e-105	353.0	COG0003@1|root,COG0071@1|root,arCOG01833@2157|Archaea,arCOG02849@2157|Archaea	2157|Archaea	P	Arsenite-activated ATPase ArsA	arsA4	-	3.6.3.16	ko:K01551,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000,ko02000,ko03110	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158380_k127_1186432_3	1459636.NTE_00419	8.718e-12	71.0	COG2968@1|root,arCOG04715@2157|Archaea,41T6R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158380_k127_1189051_0	1459636.NTE_02732	1.837e-129	421.0	COG0472@1|root,arCOG03199@2157|Archaea,41S8B@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family	-	-	2.7.8.15	ko:K01001	ko00510,ko01100,map00510,map01100	M00055	R05969	RC00002	ko00000,ko00001,ko00002,ko01000,ko01003	-	-	-	Glycos_transf_4
SRR25158380_k127_1189051_1	1459636.NTE_03018	2.518e-45	171.0	COG0221@1|root,arCOG01711@2157|Archaea,41T3F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158380_k127_1189051_2	530564.Psta_3548	1.658e-36	143.0	COG2062@1|root,COG2062@2|Bacteria,2J0N8@203682|Planctomycetes	203682|Planctomycetes	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158380_k127_1189612_0	1459636.NTE_00143	1.707e-167	538.0	COG2312@1|root,arCOG08208@2157|Archaea	2157|Archaea	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
SRR25158380_k127_1189612_4	1504981.KO116_1943	0.0003365	45.0	2DM0H@1|root,316A1@2|Bacteria,1N0X9@1224|Proteobacteria,1SMDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1189612_1	588581.Cpap_2958	4.636e-72	254.0	COG1215@1|root,COG1215@2|Bacteria,1VSBK@1239|Firmicutes,24ECY@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_1189612_2	927677.ALVU02000001_gene4617	7.179e-16	89.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_1192528_0	1459636.NTE_01052	4.163e-85	295.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_1194057_2	110319.CF8_0881	1.894e-25	116.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4DS73@85009|Propionibacteriales	201174|Actinobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158380_k127_1194057_1	1459636.NTE_02697	5.035e-26	108.0	arCOG02764@1|root,arCOG02764@2157|Archaea	2157|Archaea	S	Heavy-metal-associated domain	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158380_k127_1194057_0	930945.SiRe_0134	2.618e-113	376.0	COG0604@1|root,arCOG01458@2157|Archaea,2XPW5@28889|Crenarchaeota	28889|Crenarchaeota	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_1194963_2	1459636.NTE_00370	2.663e-10	72.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_1194963_0	269797.Mbar_A1346	3.436e-59	209.0	COG3293@1|root,arCOG03506@2157|Archaea	2157|Archaea	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
SRR25158380_k127_1194963_1	485913.Krac_9734	3.241e-22	101.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
SRR25158380_k127_1194963_3	589924.Ferp_0182	1.71e-09	64.0	COG0582@1|root,arCOG01242@2157|Archaea,2Y83U@28890|Euryarchaeota,246MT@183980|Archaeoglobi	183980|Archaeoglobi	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158380_k127_1225809_0	1229909.NSED_05640	1.033e-29	123.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158380_k127_1225809_1	1499967.BAYZ01000148_gene1744	3.952e-09	63.0	2CG94@1|root,337GB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1252629_4	1459636.NTE_03542	1.054e-22	99.0	COG3432@1|root,arCOG01063@2157|Archaea,41T7S@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_1252629_3	1459636.NTE_03541	3.997e-23	103.0	arCOG11425@1|root,arCOG11425@2157|Archaea,41T5C@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1252629_1	1459636.NTE_03540	8.032e-29	120.0	COG3794@1|root,arCOG02929@2157|Archaea,41T61@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158380_k127_1252629_2	1459636.NTE_03243	2.582e-24	112.0	2C5D3@1|root,2N5BY@2157|Archaea,41TAU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1252629_0	1459636.NTE_03308	5.012e-50	181.0	COG1515@1|root,arCOG00929@2157|Archaea	2157|Archaea	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158380_k127_1284742_1	1278304.JAFR01000013_gene707	7.901e-05	46.0	COG0270@1|root,COG0863@1|root,COG1092@1|root,COG0270@2|Bacteria,COG0863@2|Bacteria,COG1092@2|Bacteria,3WT0K@544448|Tenericutes	544448|Tenericutes	H	Methyltransferase	-	-	2.1.1.37,2.1.1.72	ko:K00558,ko:K00571	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,N6_N4_Mtase
SRR25158380_k127_1284742_0	1442598.JABW01000005_gene642	4.41e-05	51.0	COG2204@1|root,COG2204@2|Bacteria,1RHEG@1224|Proteobacteria,42UQT@68525|delta/epsilon subdivisions,2YPX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158380_k127_1284940_0	1459636.NTE_00935	1.002e-115	382.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158380_k127_1287697_1	1459636.NTE_00239	6.358e-20	90.0	COG3546@1|root,arCOG07055@2157|Archaea	2157|Archaea	P	COG3546 Mn-containing catalase	-	-	-	ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
SRR25158380_k127_1287697_0	1459636.NTE_00575	3.029e-21	96.0	arCOG04557@1|root,arCOG04557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1294030_1	983544.Lacal_2774	1.288e-62	233.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,1HZ8C@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
SRR25158380_k127_1294030_3	1229909.NSED_01010	6.929e-28	116.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_1294030_7	526218.Sterm_0782	1.553e-08	57.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,3787U@32066|Fusobacteria	32066|Fusobacteria	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
SRR25158380_k127_1294030_2	1459636.NTE_01125	6.228e-28	114.0	arCOG13015@1|root,arCOG13015@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158380_k127_1294030_6	1459636.NTE_00201	4.444e-10	65.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_1294030_4	1459636.NTE_01492	7.806e-20	98.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_1294030_0	1459636.NTE_03295	2.902e-79	273.0	COG0455@1|root,arCOG00589@2157|Archaea	2157|Archaea	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03496,ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
SRR25158380_k127_1298603_0	706587.Desti_2409	5.803e-61	216.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MQWH@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158380_k127_1303096_0	1298865.H978DRAFT_3635	2.009e-21	100.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria,467J8@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
SRR25158380_k127_1310682_1	247490.KSU1_D0999	1.686e-20	105.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_1310682_3	179408.Osc7112_3977	9.177e-14	83.0	COG0803@1|root,COG1555@1|root,COG0803@2|Bacteria,COG1555@2|Bacteria,1G2B3@1117|Cyanobacteria,1H9KB@1150|Oscillatoriales	1117|Cyanobacteria	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
SRR25158380_k127_1310682_2	227086.JGI_V11_82342	6.016e-14	83.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C,Pur_ac_phosph_N
SRR25158380_k127_1311321_7	1459636.NTE_02892	1.441e-47	171.0	COG0831@1|root,arCOG04528@2157|Archaea,41SPI@651137|Thaumarchaeota	2157|Archaea	E	(urease) gamma subunit	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
SRR25158380_k127_1311321_6	1459636.NTE_02891	3.497e-59	207.0	COG0832@1|root,arCOG04527@2157|Archaea	2157|Archaea	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
SRR25158380_k127_1311321_0	1459636.NTE_02890	0.0	1019.0	COG0804@1|root,arCOG00698@2157|Archaea,41S7M@651137|Thaumarchaeota	2157|Archaea	E	Urease, alpha subunit	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
SRR25158380_k127_1311321_1	1459636.NTE_02889	9.083e-240	750.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	2157|Archaea	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
SRR25158380_k127_1311321_9	1459636.NTE_02887	3.482e-37	146.0	arCOG06188@1|root,arCOG06188@2157|Archaea,41STJ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	UreE urease accessory protein, N-terminal domain	-	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
SRR25158380_k127_1311321_5	1229909.NSED_07665	8.118e-73	254.0	COG0830@1|root,arCOG04530@2157|Archaea,41SG4@651137|Thaumarchaeota	651137|Thaumarchaeota	O	UreF	-	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
SRR25158380_k127_1311321_4	1459636.NTE_02885	4.76e-106	347.0	COG0378@1|root,arCOG01231@2157|Archaea,41SAZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
SRR25158380_k127_1311321_3	1459636.NTE_02884	1.599e-111	368.0	COG0829@1|root,arCOG04529@2157|Archaea,41SBH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
SRR25158380_k127_1311321_8	1459636.NTE_01740	3.909e-41	155.0	COG1607@1|root,arCOG00773@2157|Archaea,41T2J@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158380_k127_1320129_1	591019.Shell_0124	1.792e-14	78.0	arCOG12413@1|root,arCOG12413@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1320129_0	1459636.NTE_02506	2.184e-117	390.0	arCOG01390@1|root,arCOG01390@2157|Archaea,41S7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_1320129_4	1131266.ARWQ01000029_gene979	0.0003189	45.0	arCOG08794@1|root,arCOG08794@2157|Archaea,41SR7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_135781_0	221288.JH992901_gene2423	2.87e-139	448.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_135781_1	436308.Nmar_0787	1.95e-32	131.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SS2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_1439124_3	1459636.NTE_02002	4.927e-20	93.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1439124_1	306281.AJLK01000058_gene1116	3.171e-51	188.0	COG2890@1|root,COG2890@2|Bacteria,1GQW3@1117|Cyanobacteria	1117|Cyanobacteria	J	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TPMT
SRR25158380_k127_1439124_2	694429.Pyrfu_0117	1.807e-37	147.0	COG1913@1|root,arCOG00458@2157|Archaea,2XQRN@28889|Crenarchaeota	28889|Crenarchaeota	O	zinc metalloprotease whose natural substrate is	amzA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
SRR25158380_k127_1439124_0	1459636.NTE_01052	5.372e-62	220.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_1467792_26	1459636.NTE_02756	1.406e-52	192.0	COG0127@1|root,arCOG04184@2157|Archaea,41SKW@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the HAM1 NTPase family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158380_k127_1467792_24	1459636.NTE_02757	3.573e-59	211.0	COG0533@1|root,arCOG01185@2157|Archaea,41SJJ@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Mn2 -dependent serine threonine protein kinase	-	-	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	Pkinase
SRR25158380_k127_1467792_31	1459636.NTE_02758	3.874e-30	123.0	arCOG10590@1|root,arCOG10590@2157|Archaea,41SSG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1467792_10	1459636.NTE_02759	2.423e-138	447.0	COG0533@1|root,arCOG01183@2157|Archaea,41SDX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37	kae1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158380_k127_1467792_6	1459636.NTE_02760	6.728e-173	550.0	COG0012@1|root,arCOG00357@2157|Archaea,41S71@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
SRR25158380_k127_1467792_5	1459636.NTE_02328	3.076e-175	560.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	2157|Archaea	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158380_k127_1467792_34	1459636.NTE_02329	2.641e-23	103.0	arCOG08657@1|root,arCOG08657@2157|Archaea,41SRB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1467792_23	1459636.NTE_02330	8.776e-61	215.0	arCOG10136@1|root,arCOG10136@2157|Archaea,41T5E@651137|Thaumarchaeota	651137|Thaumarchaeota	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
SRR25158380_k127_1467792_7	1459636.NTE_02755	1.059e-165	527.0	COG0731@1|root,arCOG04174@2157|Archaea,41SBS@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
SRR25158380_k127_1467792_16	1459636.NTE_02754	3.714e-91	307.0	COG0327@1|root,arCOG04454@2157|Archaea	2157|Archaea	S	NGG1p interacting factor 3	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1467792_29	1459636.NTE_02751	6.838e-37	140.0	COG2012@1|root,arCOG04258@2157|Archaea,41SU8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	-	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
SRR25158380_k127_1467792_1	1459636.NTE_02750	0.0	2020.0	COG0085@1|root,arCOG01762@2157|Archaea,41SF5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158380_k127_1467792_0	1459636.NTE_02749	0.0	2153.0	COG0086@1|root,arCOG04256@2157|Archaea,arCOG04257@2157|Archaea,41SB2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158380_k127_1467792_21	1459636.NTE_02747	2.601e-67	232.0	COG0195@1|root,arCOG01760@2157|Archaea,41SJQ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
SRR25158380_k127_1467792_18	1459636.NTE_02746	1.462e-79	266.0	COG0048@1|root,arCOG04255@2157|Archaea,41SIB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158380_k127_1467792_15	1459636.NTE_02745	1.085e-102	336.0	COG0049@1|root,arCOG04254@2157|Archaea,41S6U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158380_k127_1467792_8	1459636.NTE_02766	4.369e-155	497.0	arCOG08783@1|root,arCOG08783@2157|Archaea,41SFX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1467792_13	1459636.NTE_02767	1.88e-108	364.0	COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA
SRR25158380_k127_1467792_35	1459636.NTE_02768	4.603e-18	88.0	arCOG08784@1|root,arCOG08784@2157|Archaea,41SVZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1467792_36	1459636.NTE_02769	7.56e-17	82.0	arCOG08785@1|root,arCOG08785@2157|Archaea,41SVD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
SRR25158380_k127_1467792_3	1229909.NSED_01260	1.509e-232	729.0	COG4799@1|root,arCOG02705@2157|Archaea,41SEH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18604	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
SRR25158380_k127_1467792_2	1459636.NTE_02773	2.085e-240	751.0	COG0439@1|root,arCOG01590@2157|Archaea,41SXC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Carbamoyl-phosphate synthase L chain	-	-	6.4.1.2,6.4.1.3	ko:K18603	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158380_k127_1467792_28	1459636.NTE_02774	9.241e-46	171.0	COG0511@1|root,arCOG02699@2157|Archaea	2157|Archaea	I	biotin carboxyl carrier	-	-	2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K15037,ko:K18605	ko00010,ko00020,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200	M00307,M00375,M00741	R00209,R00217,R00742,R01859,R02569	RC00004,RC00040,RC00097,RC00367,RC00609,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,Biotin_lipoyl_2
SRR25158380_k127_1467792_11	1459636.NTE_02778	3.383e-135	441.0	COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158380_k127_1467792_17	1459636.NTE_02779	5.608e-87	295.0	COG1606@1|root,arCOG00043@2157|Archaea,41SF3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	tRNA methyl transferase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	QueC
SRR25158380_k127_1467792_12	1459636.NTE_02780	1.605e-125	414.0	COG1641@1|root,arCOG02701@2157|Archaea,41SDC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158380_k127_1467792_9	1459636.NTE_02800	2.801e-147	471.0	COG0039@1|root,arCOG00246@2157|Archaea,41S7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158380_k127_1467792_20	1459636.NTE_02799	2.71e-78	269.0	COG1691@1|root,arCOG02465@2157|Archaea,41SCY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158380_k127_1467792_22	1459636.NTE_02798	2.551e-63	225.0	COG0256@1|root,arCOG04088@2157|Archaea,41SQW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5e
SRR25158380_k127_1467792_14	1459636.NTE_02797	5.804e-105	343.0	COG0098@1|root,arCOG04087@2157|Archaea,41SFS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS5 family	-	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158380_k127_1467792_25	1459636.NTE_02796	7.261e-53	190.0	COG1841@1|root,arCOG04086@2157|Archaea,41SMX@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158380_k127_1467792_30	1131266.ARWQ01000012_gene1601	8.165e-36	140.0	COG0200@1|root,arCOG00779@2157|Archaea,41SQY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl15	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158380_k127_1467792_4	1459636.NTE_02794	4.536e-227	711.0	COG5253@1|root,arCOG04169@2157|Archaea,41S9X@651137|Thaumarchaeota	651137|Thaumarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
SRR25158380_k127_1467792_27	1459636.NTE_02793	1.7e-52	191.0	COG2019@1|root,arCOG01039@2157|Archaea,41SK7@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the archaeal adenylate kinase family	adkA	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
SRR25158380_k127_1467792_19	1459636.NTE_02792	6.868e-79	268.0	COG1422@1|root,arCOG02673@2157|Archaea,41SNR@651137|Thaumarchaeota	651137|Thaumarchaeota	U	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
SRR25158380_k127_1467792_32	1459636.NTE_02791	1.201e-27	114.0	COG1102@1|root,arCOG01037@2157|Archaea,41SKS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
SRR25158380_k127_1473227_0	234267.Acid_1081	9.749e-85	288.0	COG2326@1|root,COG2326@2|Bacteria,3Y44F@57723|Acidobacteria	57723|Acidobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158380_k127_1493141_0	1459636.NTE_02324	1.029e-179	574.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
SRR25158380_k127_1493141_5	1459636.NTE_02217	1.092e-62	222.0	COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota	2157|Archaea	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
SRR25158380_k127_1493141_4	1459636.NTE_02683	1.452e-85	289.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158380_k127_1493141_6	1459636.NTE_02682	1.083e-40	160.0	arCOG08818@1|root,arCOG08818@2157|Archaea,41SVV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1493141_1	1459636.NTE_02663	5.133e-169	539.0	COG2046@1|root,arCOG04191@2157|Archaea,41SER@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158380_k127_1493141_2	1459636.NTE_02662	5.262e-108	355.0	COG0175@1|root,arCOG00124@2157|Archaea,41S9Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158380_k127_1493141_3	1459636.NTE_02661	2.156e-106	361.0	COG1254@1|root,arCOG00643@2157|Archaea	2157|Archaea	C	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Acylphosphatase
SRR25158380_k127_1653321_1	1459636.NTE_03146	4.11e-40	156.0	COG0071@1|root,arCOG01833@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158380_k127_1653321_2	489825.LYNGBM3L_26300	0.0004132	44.0	COG2241@1|root,COG2241@2|Bacteria,1G2V3@1117|Cyanobacteria,1H9B7@1150|Oscillatoriales	1117|Cyanobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	-	-	-	-	-	-	-	-	-	-	TP_methylase
SRR25158380_k127_1653321_0	1337936.IJ00_25245	5.505e-64	230.0	COG0477@1|root,COG1359@1|root,COG0477@2|Bacteria,COG1359@2|Bacteria,1GD25@1117|Cyanobacteria,1HQJG@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158380_k127_1662333_1	1459636.NTE_00907	6.878e-18	85.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K03294,ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6,2.A.3.2	-	-	Usp
SRR25158380_k127_1662333_0	1313301.AUGC01000001_gene1411	1.658e-205	651.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158380_k127_1670665_0	98439.AJLL01000028_gene4235	1.689e-142	459.0	COG0667@1|root,COG0667@2|Bacteria,1G1XK@1117|Cyanobacteria,1JHF1@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_1670665_1	1267533.KB906736_gene1024	2.873e-12	74.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1670665_2	1521187.JPIM01000012_gene1666	3.166e-09	59.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
SRR25158380_k127_1670813_5	877455.Metbo_2457	2.721e-56	200.0	COG1839@1|root,arCOG04298@2157|Archaea,2XY40@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
SRR25158380_k127_1670813_10	453591.Igni_1212	1.065e-11	71.0	COG0517@1|root,COG1522@1|root,arCOG00606@2157|Archaea,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,CBS
SRR25158380_k127_1670813_1	529709.PYCH_06490	2.469e-185	604.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,242XT@183968|Thermococci	183968|Thermococci	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
SRR25158380_k127_1670813_8	399549.Msed_0931	5.432e-19	90.0	COG0298@1|root,arCOG04427@2157|Archaea	2157|Archaea	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158380_k127_1670813_2	671065.MetMK1DRAFT_00005540	5.661e-142	459.0	COG0409@1|root,arCOG04428@2157|Archaea,2XPKY@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM hydrogenase formation HypD protein	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158380_k127_1670813_7	671065.MetMK1DRAFT_00005530	8.372e-44	169.0	COG0235@1|root,arCOG04226@2157|Archaea,2XQGF@28889|Crenarchaeota	28889|Crenarchaeota	G	Class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158380_k127_1670813_6	399549.Msed_0929	2.226e-45	173.0	COG0235@1|root,arCOG04226@2157|Archaea,2XR76@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158380_k127_1670813_3	399549.Msed_0933	1.668e-122	402.0	COG0309@1|root,arCOG00636@2157|Archaea,2XPSN@28889|Crenarchaeota	28889|Crenarchaeota	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_1670813_9	517417.Cpar_0318	6.918e-18	89.0	COG1941@1|root,COG1941@2|Bacteria,1FDE2@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
SRR25158380_k127_1670813_4	237368.SCABRO_02487	5.303e-86	299.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
SRR25158380_k127_1670813_0	589924.Ferp_2110	1.709e-229	734.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,245QA@183980|Archaeoglobi	183980|Archaeoglobi	G	PFAM Pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158380_k127_17824_3	1459636.NTE_03005	3.943e-07	54.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_17824_0	1459636.NTE_00897	1.654e-63	224.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_17824_2	1121904.ARBP01000009_gene4228	2.02e-11	75.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47N6B@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_1850118_2	144197.XP_008305176.1	1.973e-05	54.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata,496SD@7742|Vertebrata,49XMF@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
SRR25158380_k127_1850118_0	1459636.NTE_01667	1.564e-31	127.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1859922_0	1094980.Mpsy_2342	8.135e-18	95.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	gvpD	-	-	-	-	-	-	-	-	-	-	-	GvpD
SRR25158380_k127_1859922_1	1459636.NTE_03005	3.561e-15	76.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_1871830_0	1459636.NTE_03258	4.505e-20	91.0	arCOG10546@1|root,arCOG10546@2157|Archaea,41SRD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1871830_1	768672.Desfe_1252	1.92e-10	67.0	arCOG00144@1|root,arCOG00144@2157|Archaea,2XQ4R@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_187456_1	1459636.NTE_02412	6.771e-15	77.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_187456_0	1459636.NTE_01494	2.27e-16	81.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01494|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_18922_3	1229909.NSED_05835	4.642e-08	60.0	arCOG08716@1|root,arCOG10358@1|root,arCOG08716@2157|Archaea,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_18922_0	1459636.NTE_03540	2.453e-32	132.0	COG3794@1|root,arCOG02929@2157|Archaea,41T61@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158380_k127_18922_1	1459636.NTE_03541	6.437e-28	117.0	arCOG11425@1|root,arCOG11425@2157|Archaea,41T5C@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_18922_2	1459636.NTE_03542	5.645e-22	97.0	COG3432@1|root,arCOG01063@2157|Archaea,41T7S@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_1897390_5	1459636.NTE_02931	4.581e-108	356.0	COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158380_k127_1897390_12	1459636.NTE_00858	5.978e-69	242.0	COG0367@1|root,arCOG00071@2157|Archaea,41SIX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRR25158380_k127_1897390_8	1459636.NTE_00856	3.566e-96	321.0	COG0720@1|root,arCOG02172@2157|Archaea,41SY8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158380_k127_1897390_0	1459636.NTE_03216	0.0	1138.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_1897390_17	1459636.NTE_03214	8.557e-48	175.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1897390_7	1459636.NTE_00432	3.537e-102	345.0	COG0446@1|root,arCOG01064@2157|Archaea,41SZR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_1897390_25	1459636.NTE_01916	5.705e-21	95.0	COG0640@1|root,arCOG04056@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5,TrmB
SRR25158380_k127_1897390_3	1459636.NTE_01915	9.856e-133	434.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	2157|Archaea	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
SRR25158380_k127_1897390_4	1459636.NTE_02299	1.444e-121	398.0	COG2835@1|root,arCOG01792@1|root,arCOG01792@2157|Archaea,arCOG04124@2157|Archaea,41T4S@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1897390_6	1459636.NTE_01313	6.497e-105	356.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1897390_16	436308.Nmar_1625	2.476e-57	208.0	COG1756@1|root,arCOG04122@2157|Archaea,41T2T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	-	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
SRR25158380_k127_1897390_24	1459636.NTE_03109	3.005e-23	102.0	COG2023@1|root,arCOG04345@2157|Archaea,41STS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
SRR25158380_k127_1897390_15	1459636.NTE_03108	1.339e-59	209.0	COG2238@1|root,arCOG01344@2157|Archaea,41SK1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	-	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
SRR25158380_k127_1897390_21	1459636.NTE_03107	5.92e-34	132.0	COG2118@1|root,arCOG04179@2157|Archaea,41SR0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
SRR25158380_k127_1897390_23	1229909.NSED_03185	2.875e-26	117.0	arCOG03727@1|root,arCOG03727@2157|Archaea,41STD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
SRR25158380_k127_1897390_20	1459636.NTE_03120	5.003e-44	161.0	COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
SRR25158380_k127_1897390_27	1459636.NTE_03119	4.317e-16	79.0	COG2051@1|root,arCOG04108@2157|Archaea,41SUD@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps27e	-	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
SRR25158380_k127_1897390_26	386456.JQKN01000013_gene3046	2.377e-20	100.0	COG2266@1|root,arCOG01871@2157|Archaea,2XZP4@28890|Euryarchaeota,23P5D@183925|Methanobacteria	183925|Methanobacteria	M	Cytidylyltransferase	cobY	-	2.7.7.62	ko:K19712	ko00860,ko01100,map00860,map01100	-	R05222	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158380_k127_1897390_19	1459636.NTE_03117	2.265e-45	173.0	COG0368@1|root,arCOG04338@2157|Archaea,41SI6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158380_k127_1897390_11	1459636.NTE_03116	3.092e-84	290.0	COG1270@1|root,arCOG04274@2157|Archaea,41S6I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
SRR25158380_k127_1897390_10	1459636.NTE_03115	3.793e-85	290.0	COG1492@1|root,arCOG00105@2157|Archaea,41SG6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA
SRR25158380_k127_1897390_9	1459636.NTE_03114	7.275e-89	307.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158380_k127_1897390_1	1459636.NTE_03113	2.112e-177	561.0	COG0136@1|root,arCOG00494@2157|Archaea,41SFD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate-semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158380_k127_1897390_2	1459636.NTE_03111	7.851e-147	469.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158380_k127_1897390_28	1459636.NTE_00099	1.368e-10	63.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158380_k127_1897390_13	1459636.NTE_01473	1.135e-62	228.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158380_k127_1897390_22	1459636.NTE_00321	7.288e-32	127.0	arCOG11305@1|root,arCOG11305@2157|Archaea,41T7G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1897390_18	1459636.NTE_02875	2.187e-47	178.0	COG0637@1|root,arCOG02293@2157|Archaea	2157|Archaea	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,5.4.2.6	ko:K01091,ko:K01838,ko:K07025	ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130	-	R01334,R02728,R11310	RC00017,RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158380_k127_1897390_14	1459636.NTE_02959	9.548e-60	213.0	COG2095@1|root,arCOG01997@2157|Archaea	2157|Archaea	U	UPF0056 membrane protein	snatA	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158380_k127_1929109_0	1459636.NTE_00183	1.721e-57	215.0	COG0477@1|root,arCOG00130@2157|Archaea,arCOG00134@2157|Archaea	2157|Archaea	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
SRR25158380_k127_1932_6	1459636.NTE_00045	3.155e-111	364.0	COG0573@1|root,arCOG00167@2157|Archaea,41SYE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158380_k127_1932_7	42256.RradSPS_0703	5.103e-66	236.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158380_k127_1932_4	1459636.NTE_00041	2.769e-124	408.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
SRR25158380_k127_1932_1	1459636.NTE_00046	8.981e-137	443.0	COG0226@1|root,arCOG08033@1|root,arCOG00213@2157|Archaea,arCOG08033@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158380_k127_1932_9	1459636.NTE_01512	2.674e-24	108.0	COG2236@1|root,arCOG00040@2157|Archaea,41TA1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosyltransferase	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_1932_3	1459636.NTE_00018	1.824e-124	405.0	COG0115@1|root,arCOG02297@2157|Archaea,41SD5@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158380_k127_1932_0	1459636.NTE_00019	9.206e-185	589.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158380_k127_1932_5	1459636.NTE_00030	1.368e-115	381.0	COG1819@1|root,arCOG01393@2157|Archaea,41T16@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
SRR25158380_k127_1932_8	436308.Nmar_0884	6.855e-29	123.0	arCOG10557@1|root,arCOG10557@2157|Archaea,41T1I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_1932_2	1459636.NTE_02001	2.585e-127	413.0	COG1131@1|root,arCOG00194@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158380_k127_19534_0	1041146.ATZB01000034_gene562	4.615e-134	441.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2TR2U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_198527_0	864069.MicloDRAFT_00048630	8.837e-52	188.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,1JUB9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K22479	-	-	-	-	ko00000	-	-	-	Acetyltransf_3
SRR25158380_k127_19938_2	1459636.NTE_02865	2.822e-14	74.0	arCOG10406@1|root,arCOG10406@2157|Archaea,41SVU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger, C2H2 type	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2
SRR25158380_k127_19938_1	1459636.NTE_00658	6.131e-25	107.0	arCOG10584@1|root,arCOG10584@2157|Archaea,41SV6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial Fe(2+) trafficking	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR25158380_k127_19938_3	1459636.NTE_00657	1.939e-10	67.0	arCOG08772@1|root,arCOG08772@2157|Archaea,41SSX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_19938_0	1459636.NTE_00656	1.193e-143	462.0	COG0104@1|root,arCOG04387@2157|Archaea,41SCA@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158380_k127_200550_0	1459636.NTE_00560	8.275e-27	115.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_200977_2	304371.MCP_2209	0.000778	46.0	arCOG05149@1|root,arCOG05149@2157|Archaea,2Y4ZG@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_200977_1	368407.Memar_1639	3.141e-06	53.0	arCOG05148@1|root,arCOG05148@2157|Archaea,2Y4WW@28890|Euryarchaeota,2NB8P@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_200977_0	1229909.NSED_01010	9.906e-08	58.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_202140_1	1459636.NTE_01449	4.42e-25	112.0	COG0494@1|root,COG1853@1|root,arCOG01083@2157|Archaea,arCOG02017@2157|Archaea	2157|Archaea	L	PFAM flavin reductase domain protein, FMN-binding	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016722,GO:0016723,GO:0032553,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.16.1.10,3.6.1.55	ko:K03574,ko:K18915	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Flavin_Reduct,NUDIX
SRR25158380_k127_202140_4	306281.AJLK01000188_gene1256	2.959e-12	74.0	COG0515@1|root,COG0515@2|Bacteria,1G0M9@1117|Cyanobacteria,1JJCN@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,PsbP
SRR25158380_k127_202140_0	1382359.JIAL01000001_gene1362	7.431e-109	373.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_202140_3	290317.Cpha266_1549	2.975e-13	75.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2022086_0	1459636.NTE_03296	6.399e-64	228.0	COG0467@1|root,arCOG01171@2157|Archaea	2157|Archaea	T	Circadian clock protein KaiC	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATPase,Arf,Robl_LC7,zf-FCS
SRR25158380_k127_2022086_4	1459636.NTE_01491	6.165e-16	85.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2022086_2	1459636.NTE_02866	4.397e-39	150.0	arCOG08678@1|root,arCOG08678@2157|Archaea,41SR1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2022086_1	1459636.NTE_01028	1.935e-59	211.0	COG0125@1|root,arCOG01891@2157|Archaea,41T33@651137|Thaumarchaeota	651137|Thaumarchaeota	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158380_k127_2022086_7	1459636.NTE_00560	0.0007936	44.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2022086_3	1459636.NTE_01667	3.169e-35	136.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2039825_0	1229909.NSED_08345	3.823e-31	126.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158380_k127_2039825_2	877418.ATWV01000003_gene560	0.0002033	49.0	COG0745@1|root,COG0745@2|Bacteria,2J7CF@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_2042307_20	509191.AEDB02000073_gene1833	2.332e-15	85.0	COG1716@1|root,COG3534@1|root,COG1716@2|Bacteria,COG3534@2|Bacteria,1TS4P@1239|Firmicutes,24BY6@186801|Clostridia,3WGRR@541000|Ruminococcaceae	186801|Clostridia	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158380_k127_2042307_10	1459636.NTE_03209	6.356e-57	204.0	COG1096@1|root,arCOG00676@2157|Archaea,41SQA@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	-
SRR25158380_k127_2042307_17	1459636.NTE_02015	5.607e-25	106.0	COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
SRR25158380_k127_2042307_11	1459636.NTE_01318	3.977e-40	149.0	arCOG08720@1|root,arCOG08720@2157|Archaea,41STI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2024
SRR25158380_k127_2042307_1	1459636.NTE_03316	1.653e-191	605.0	COG1236@1|root,arCOG00541@2157|Archaea,41SAJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B_6,RMMBL
SRR25158380_k127_2042307_7	1459636.NTE_01567	8.446e-72	253.0	COG0122@1|root,arCOG00464@2157|Archaea,41SHE@651137|Thaumarchaeota	651137|Thaumarchaeota	L	8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158380_k127_2042307_14	1459636.NTE_02300	1.295e-30	126.0	arCOG08690@1|root,arCOG08690@2157|Archaea,41T98@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2042307_13	1121930.AQXG01000005_gene616	2.479e-34	138.0	COG0622@1|root,COG0622@2|Bacteria,4PJA1@976|Bacteroidetes,1IZVM@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158380_k127_2042307_9	1459636.NTE_02658	1.119e-57	208.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	hadL	-	3.1.3.18,3.8.1.2,3.8.1.3	ko:K01091,ko:K01560,ko:K01561,ko:K07025	ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130	-	R01334,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158380_k127_2042307_2	1459636.NTE_00824	4.85e-160	511.0	COG1759@1|root,arCOG04346@2157|Archaea,41S79@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Domain of unknown function (DUF1297)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
SRR25158380_k127_2042307_15	1459636.NTE_00825	9.198e-27	112.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158380_k127_2042307_12	1459636.NTE_01025	4.421e-36	139.0	arCOG08775@1|root,arCOG08775@2157|Archaea,41T9K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2042307_8	1459636.NTE_01026	2.899e-70	245.0	COG0528@1|root,arCOG00858@2157|Archaea,41T1R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158380_k127_2042307_3	1459636.NTE_01027	4.642e-150	484.0	COG1078@1|root,arCOG04430@2157|Archaea,41T0P@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158380_k127_2042307_16	1459636.NTE_02088	3.407e-26	111.0	arCOG11950@1|root,arCOG11950@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	bPH_3
SRR25158380_k127_2042307_5	436308.Nmar_0774	3.828e-82	281.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158380_k127_2042307_0	1459636.NTE_00682	0.0	1195.0	COG0417@1|root,arCOG15272@2157|Archaea,41S91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
SRR25158380_k127_2042307_4	1459636.NTE_00681	2.305e-104	348.0	COG0010@1|root,arCOG01700@2157|Archaea,41T03@651137|Thaumarchaeota	2157|Archaea	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158380_k127_2042307_19	445975.COLSTE_02536	3.785e-18	89.0	2AU0F@1|root,31JKB@2|Bacteria,2IT83@201174|Actinobacteria	201174|Actinobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2048925_0	1459636.NTE_00046	1.217e-139	452.0	COG0226@1|root,arCOG08033@1|root,arCOG00213@2157|Archaea,arCOG08033@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158380_k127_2048925_1	1459636.NTE_00041	6.491e-36	141.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
SRR25158380_k127_2049107_5	1131266.ARWQ01000002_gene639	7.506e-20	96.0	COG1917@1|root,arCOG03444@2157|Archaea,41SV4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_2049107_9	1173025.GEI7407_1588	0.0003446	50.0	2DN4E@1|root,32VGA@2|Bacteria,1G7ZM@1117|Cyanobacteria,1HCGT@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2049107_0	1459636.NTE_03539	5.257e-165	534.0	COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158380_k127_2049107_2	1459636.NTE_01521	4.921e-138	450.0	COG0160@1|root,arCOG00915@2157|Archaea,41TBD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.76	ko:K00823,ko:K00836	ko00250,ko00260,ko00410,ko00640,ko00650,ko01100,ko01120,ko01210,ko01230,map00250,map00260,map00410,map00640,map00650,map01100,map01120,map01210,map01230	M00027,M00033	R00908,R01648,R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_2049107_4	1459636.NTE_00036	1.266e-56	203.0	COG0494@1|root,arCOG01073@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158380_k127_2049107_6	436308.Nmar_0062	5.763e-17	87.0	COG0463@1|root,arCOG00894@2157|Archaea,41SAS@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158380_k127_2049107_7	1459636.NTE_03121	3.698e-15	77.0	arCOG06947@1|root,arCOG06947@2157|Archaea	2157|Archaea	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2,zf-C2H2_4
SRR25158380_k127_2049107_1	1459636.NTE_01711	6.226e-151	493.0	COG0277@1|root,arCOG00337@2157|Archaea,41T0E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158380_k127_2049107_3	1459636.NTE_00791	5.652e-93	322.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	2157|Archaea	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_2056648_1	1223523.H340_21271	1.88e-09	63.0	COG1359@1|root,COG1359@2|Bacteria,2IR79@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158380_k127_2056648_0	1459636.NTE_03510	7.084e-99	333.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158380_k127_2056886_1	313628.LNTAR_20423	5.405e-11	67.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	phcR	-	-	ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	HATPase_c,HDOD,Response_reg
SRR25158380_k127_2058360_7	1459636.NTE_00832	8.163e-137	453.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2058360_4	1459636.NTE_01645	6.275e-158	504.0	COG1260@1|root,arCOG04213@2157|Archaea,41SEZ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158380_k127_2058360_10	1459636.NTE_02318	3.28e-105	347.0	COG1378@1|root,arCOG02038@2157|Archaea,41SFR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
SRR25158380_k127_2058360_0	1459636.NTE_00800	0.0	1292.0	COG0480@1|root,arCOG01559@2157|Archaea,41S9B@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158380_k127_2058360_6	1459636.NTE_01978	1.18e-139	454.0	COG3769@1|root,arCOG04158@2157|Archaea	2157|Archaea	S	Mannosyl-3-phosphoglycerate synthase	mngA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
SRR25158380_k127_2058360_18	1459636.NTE_00822	2.044e-37	151.0	arCOG08714@1|root,arCOG08714@2157|Archaea,41SPW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2058360_14	1459636.NTE_00823	8.774e-56	198.0	COG1259@1|root,arCOG01759@2157|Archaea,41SQI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158380_k127_2058360_22	1459636.NTE_02851	4.227e-20	97.0	arCOG10597@1|root,arCOG10597@2157|Archaea	2157|Archaea	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2058360_13	436308.Nmar_0257	2.087e-57	203.0	COG1695@1|root,arCOG00002@2157|Archaea,41SN8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158380_k127_2058360_8	1459636.NTE_01742	3.213e-120	392.0	COG2513@1|root,arCOG00581@2157|Archaea,41SEN@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158380_k127_2058360_5	1459636.NTE_02468	1.649e-149	486.0	COG0621@1|root,arCOG01358@2157|Archaea,41SB9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	MiaB-like tRNA modifying enzyme	-	-	2.8.4.5	ko:K15865	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158380_k127_2058360_26	1459636.NTE_02466	7.507e-14	72.0	arCOG11612@1|root,arCOG11612@2157|Archaea,41T8D@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2058360_24	1459636.NTE_02463	7.781e-19	86.0	COG2167@1|root,arCOG04177@2157|Archaea,41SUT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
SRR25158380_k127_2058360_20	1459636.NTE_02464	5.035e-32	127.0	COG2097@1|root,arCOG04473@2157|Archaea,41STQ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	-	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
SRR25158380_k127_2058360_23	1459636.NTE_00426	1.024e-19	92.0	arCOG08809@1|root,arCOG08809@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2058360_19	1459636.NTE_00425	4.264e-34	138.0	COG1711@1|root,arCOG00551@2157|Archaea,41SVQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
SRR25158380_k127_2058360_1	1459636.NTE_00424	4.529e-250	778.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_2058360_21	1173263.Syn7502_01281	3.239e-25	107.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1H11A@1129|Synechococcus	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158380_k127_2058360_2	1459636.NTE_02856	5.161e-241	749.0	COG5256@1|root,arCOG01561@2157|Archaea,41SD2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158380_k127_2058360_15	1459636.NTE_02855	4.454e-55	193.0	COG0051@1|root,arCOG01758@2157|Archaea,41SQB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158380_k127_2058360_29	111780.Sta7437_2108	1.075e-06	57.0	COG0515@1|root,COG0515@2|Bacteria,1G0M9@1117|Cyanobacteria,3VI7U@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158380_k127_2058360_9	1229909.NSED_01900	8.985e-116	375.0	COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158380_k127_2058360_16	1459636.NTE_01388	1.192e-52	189.0	COG1717@1|root,arCOG00781@2157|Archaea,41SP5@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
SRR25158380_k127_2058360_12	1459636.NTE_01387	1.83e-60	211.0	COG2147@1|root,arCOG04089@2157|Archaea,41SVC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
SRR25158380_k127_2058360_11	1459636.NTE_01385	1.187e-64	230.0	COG1650@1|root,arCOG01616@2157|Archaea,41SM3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
SRR25158380_k127_2058360_17	1459636.NTE_02877	1.423e-38	148.0	arCOG08781@1|root,arCOG08781@2157|Archaea	1459636.NTE_02877|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2058360_3	1459636.NTE_03103	2.732e-212	675.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158380_k127_2059285_2	436308.Nmar_0654	2.387e-75	257.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158380_k127_2059285_4	1459636.NTE_00763	1.587e-69	244.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea,41SFU@651137|Thaumarchaeota	2157|Archaea	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158380_k127_2059285_3	521011.Mpal_1345	4.449e-73	257.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_2059285_7	1459636.NTE_03227	9.319e-12	66.0	arCOG07262@1|root,arCOG07262@2157|Archaea	2157|Archaea	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2059285_0	1459636.NTE_01166	6.395e-212	666.0	COG1012@1|root,arCOG01252@2157|Archaea,41T0F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135,ko:K18601	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158380_k127_2059285_1	1459636.NTE_01163	1.489e-173	549.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_20722_3	1121121.KB894308_gene201	2.222e-26	119.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_20722_0	1459636.NTE_01508	2.901e-43	165.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_20722_1	1459636.NTE_02871	1.092e-37	144.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
SRR25158380_k127_2104171_3	1459636.NTE_01729	4.535e-14	74.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158380_k127_2104171_0	1123368.AUIS01000008_gene2277	4.272e-98	329.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,2NCYJ@225057|Acidithiobacillales	1236|Gammaproteobacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158380_k127_2104171_1	933801.Ahos_0961	3.337e-66	249.0	COG0433@1|root,arCOG00283@2157|Archaea,2XST3@28889|Crenarchaeota	28889|Crenarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
SRR25158380_k127_215706_0	1459636.NTE_02733	2.955e-239	760.0	COG1204@1|root,arCOG00553@2157|Archaea,41SAK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
SRR25158380_k127_2158907_2	1459636.NTE_03049	8.381e-64	224.0	COG0122@1|root,arCOG00464@2157|Archaea	2157|Archaea	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158380_k127_2158907_0	1459636.NTE_00523	2.915e-133	434.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	2157|Archaea	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665,ko:K06883	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158380_k127_2158907_3	1499967.BAYZ01000057_gene4701	1.193e-60	216.0	COG1043@1|root,COG1043@2|Bacteria	2|Bacteria	M	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
SRR25158380_k127_2158907_1	1131266.ARWQ01000008_gene303	1.762e-90	304.0	COG0726@1|root,arCOG02877@2157|Archaea	2157|Archaea	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158380_k127_2200969_6	1459636.NTE_01922	4.683e-65	233.0	COG0524@1|root,arCOG00016@2157|Archaea,41SJA@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158380_k127_2200969_8	436308.Nmar_1094	1.41e-22	102.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SQT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2200969_5	525904.Tter_0974	1.569e-71	261.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	MA20_15190	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158380_k127_2200969_1	1459636.NTE_01932	2.318e-94	323.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_2200969_9	575540.Isop_0124	1.942e-14	81.0	COG2931@1|root,COG2931@2|Bacteria,2J06X@203682|Planctomycetes	203682|Planctomycetes	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158380_k127_2200969_0	1459636.NTE_03297	4.488e-166	532.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158380_k127_2200969_10	1459636.NTE_01513	6.473e-13	69.0	arCOG10403@1|root,arCOG10403@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2200969_4	5888.CAK87026	1.121e-73	263.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRR25158380_k127_2200969_7	1459636.NTE_02444	5.903e-38	154.0	arCOG01214@1|root,arCOG01214@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,Trehalose_PPase
SRR25158380_k127_2200969_3	1459636.NTE_01571	1.045e-73	256.0	COG0596@1|root,arCOG01653@2157|Archaea	2157|Archaea	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158380_k127_2200969_2	1459636.NTE_00139	9.916e-85	297.0	COG0438@1|root,arCOG04796@2157|Archaea,41T9D@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158380_k127_2200969_13	1459636.NTE_01573	2.197e-05	50.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_2201987_0	1463864.JOGO01000014_gene4715	4.7e-30	123.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2203415_0	1459636.NTE_02191	1.15e-22	103.0	COG1873@1|root,arCOG02155@2157|Archaea	2157|Archaea	S	PRC-barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158380_k127_2203550_0	1459636.NTE_01491	5.051e-20	93.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2203550_3	1304885.AUEY01000025_gene2743	0.0006817	46.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2X5PV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158380_k127_2203550_1	153721.MYP_3078	2.058e-10	72.0	2EYGB@1|root,33RQ8@2|Bacteria,4P0AB@976|Bacteroidetes,47T9K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2203550_2	1459636.NTE_00429	7.002e-05	48.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2204367_6	1459636.NTE_03322	1.044e-139	454.0	COG0499@1|root,arCOG04137@2157|Archaea,41S9I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158380_k127_2204367_3	1459636.NTE_03323	5.69e-252	788.0	COG0143@1|root,arCOG00810@2157|Archaea,41SAF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158380_k127_2204367_14	1459636.NTE_03324	1.12e-60	214.0	COG1056@1|root,arCOG00972@2157|Archaea,41T2U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158380_k127_2204367_4	1459636.NTE_01112	5.904e-166	526.0	COG0059@1|root,arCOG04465@2157|Archaea,41S65@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158380_k127_2204367_9	1459636.NTE_03482	2.729e-118	390.0	COG0330@1|root,arCOG01915@2157|Archaea,41SYP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158380_k127_2204367_12	1459636.NTE_01111	3.195e-64	222.0	COG2185@1|root,arCOG01710@2157|Archaea,41SJN@651137|Thaumarchaeota	651137|Thaumarchaeota	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158380_k127_2204367_10	1459636.NTE_01109	1.656e-116	383.0	COG1703@1|root,arCOG01226@2157|Archaea,41SFN@651137|Thaumarchaeota	651137|Thaumarchaeota	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158380_k127_2204367_1	1459636.NTE_01108	4.267e-263	818.0	COG1884@1|root,arCOG04232@2157|Archaea,41SBW@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158380_k127_2204367_5	1459636.NTE_02175	9.136e-154	491.0	COG0473@1|root,arCOG01163@2157|Archaea,41SAA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_2204367_13	1459636.NTE_01107	2.341e-61	213.0	COG0346@1|root,arCOG02706@2157|Archaea,41SQS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158380_k127_2204367_2	1459636.NTE_02176	2.655e-252	787.0	COG0119@1|root,arCOG02092@2157|Archaea,41SBX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158380_k127_2204367_11	1459636.NTE_02177	8.963e-70	240.0	COG0440@1|root,arCOG04445@2157|Archaea,41SNS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158380_k127_2204367_0	1459636.NTE_02178	1.014e-314	969.0	COG0028@1|root,arCOG01998@2157|Archaea,41S63@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158380_k127_2204367_15	1123366.TH3_17402	2.345e-27	119.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2JSXK@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,FecR,HemolysinCabind,Laminin_G_3
SRR25158380_k127_2204367_8	1459636.NTE_02180	2.228e-124	403.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158380_k127_2204367_7	1459636.NTE_02181	1.473e-127	418.0	COG1063@1|root,arCOG01459@2157|Archaea,41S98@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_2204367_16	1131266.ARWQ01000002_gene493	4.62e-16	79.0	arCOG04508@1|root,arCOG04508@2157|Archaea,41SVW@651137|Thaumarchaeota	651137|Thaumarchaeota	P	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
SRR25158380_k127_2204367_17	1459636.NTE_00107	6.051e-09	59.0	arCOG08792@1|root,arCOG08792@2157|Archaea,41SUG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2205790_1	647113.Metok_1361	3.504e-20	101.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,23R54@183939|Methanococci	183939|Methanococci	S	SMART Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
SRR25158380_k127_2205790_0	682795.AciX8_2416	9.303e-22	98.0	COG2124@1|root,COG2124@2|Bacteria,3Y2TQ@57723|Acidobacteria,2JI8Z@204432|Acidobacteriia	204432|Acidobacteriia	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158380_k127_2206278_1	391595.RLO149_c022000	2.638e-08	60.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG5278@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5278@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2P2PM@2433|Roseobacter	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
SRR25158380_k127_2206278_0	1459636.NTE_00550	1.51e-27	114.0	COG0655@1|root,COG2146@1|root,arCOG02578@2157|Archaea,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158380_k127_2208945_3	1459636.NTE_02770	1.207e-14	74.0	arCOG11305@1|root,arCOG11305@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2208945_2	436308.Nmar_0202	1.168e-14	76.0	COG0640@1|root,arCOG00731@2157|Archaea,41T40@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158380_k127_2208945_4	4787.PITG_01181T0	2.237e-11	69.0	COG0526@1|root,KOG2699@1|root,KOG0907@2759|Eukaryota,KOG2699@2759|Eukaryota,3QBRY@4776|Peronosporales	4776|Peronosporales	O	PUB domain	-	-	-	-	-	-	-	-	-	-	-	-	PUB,Thioredoxin,UBA
SRR25158380_k127_2208945_0	1173024.KI912149_gene5922	5.217e-119	390.0	COG1741@1|root,COG1741@2|Bacteria,1G41Z@1117|Cyanobacteria,1JJVK@1189|Stigonemataceae	1117|Cyanobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158380_k127_2208945_1	1459636.NTE_02711	5.414e-38	148.0	COG3224@1|root,arCOG08661@2157|Archaea	2157|Archaea	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
SRR25158380_k127_2213296_1	1459636.NTE_02527	7.178e-49	183.0	COG0819@1|root,arCOG01128@2157|Archaea,41TB7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_2213296_0	1459636.NTE_02548	6.272e-105	350.0	COG0142@1|root,arCOG01727@2157|Archaea,41SC6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158380_k127_2214443_0	269797.Mbar_A3620	2.976e-46	172.0	COG3291@1|root,COG3391@1|root,arCOG03991@1|root,arCOG02510@2157|Archaea,arCOG03563@2157|Archaea,arCOG03991@2157|Archaea,2Y2RX@28890|Euryarchaeota,2NAHT@224756|Methanomicrobia	224756|Methanomicrobia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PKD
SRR25158380_k127_2214443_1	1459636.NTE_01491	2.328e-14	78.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2214443_2	1459636.NTE_02333	9.485e-12	69.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2214583_0	436308.Nmar_1695	1.006e-80	276.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158380_k127_2214583_1	436308.Nmar_0204	2.471e-29	124.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2214583_2	1459636.NTE_03327	3.538e-06	57.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2216135_1	1459636.NTE_00252	2.6e-43	162.0	COG0599@1|root,arCOG02148@2157|Archaea	2157|Archaea	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158380_k127_2216135_0	1459636.NTE_00914	1.03e-140	466.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158380_k127_2216135_2	1150474.JQJI01000011_gene64	3.317e-41	167.0	COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SRR25158380_k127_2216135_3	1089551.KE386572_gene1676	1.284e-13	80.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	CAP,HCBP_related,HemolysinCabind,PPC
SRR25158380_k127_2219532_0	1459636.NTE_00994	1.632e-180	568.0	COG1454@1|root,arCOG00984@2157|Archaea,41SFC@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	ko:K18602	ko00720,ko01120,map00720,map01120	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158380_k127_2219532_1	1459636.NTE_00995	1.27e-97	322.0	COG4276@1|root,arCOG04604@2157|Archaea,41SI9@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158380_k127_2230396_20	1459636.NTE_01681	1.27e-09	63.0	COG1676@1|root,arCOG01701@2157|Archaea,41SJY@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
SRR25158380_k127_2230396_6	1459636.NTE_01680	2.309e-79	267.0	COG0197@1|root,arCOG04113@2157|Archaea,41SKN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158380_k127_2230396_4	4081.Solyc07g066600.2.1	3.652e-108	363.0	COG0126@1|root,KOG1367@2759|Eukaryota,37R6T@33090|Viridiplantae,3GA5G@35493|Streptophyta,44MF5@71274|asterids	35493|Streptophyta	G	Phosphoglycerate kinase	-	GO:0002237,GO:0003674,GO:0003824,GO:0004618,GO:0004672,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005829,GO:0005886,GO:0005911,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009506,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009743,GO:0009746,GO:0009749,GO:0009987,GO:0010033,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0030054,GO:0031090,GO:0032787,GO:0034284,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036211,GO:0042221,GO:0042866,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048046,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0055044,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0098588,GO:0098805,GO:0140096,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158380_k127_2230396_16	1459636.NTE_03026	4.797e-24	105.0	arCOG08645@1|root,arCOG08645@2157|Archaea,41STW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2230396_12	1459636.NTE_01654	3.239e-36	140.0	COG1990@1|root,arCOG04228@2157|Archaea,41ST1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Peptidyl-tRNA hydrolase PTH2	-	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
SRR25158380_k127_2230396_3	1459636.NTE_01655	5.994e-125	411.0	COG0644@1|root,arCOG00570@2157|Archaea,41SB5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2230396_13	1459636.NTE_01656	4.725e-30	119.0	COG2888@1|root,arCOG01989@2157|Archaea,41T83@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zn-ribbon RNA-binding protein with a function in translation	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_2230396_15	1459636.NTE_01657	9.869e-27	113.0	COG2092@1|root,arCOG01988@2157|Archaea,41SS1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
SRR25158380_k127_2230396_17	1459636.NTE_01660	3.886e-22	96.0	arCOG07192@1|root,arCOG07192@2157|Archaea,41SVA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2230396_2	1459636.NTE_01661	9.029e-147	470.0	COG0109@1|root,arCOG00479@2157|Archaea,41SDQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158380_k127_2230396_7	1459636.NTE_01663	1.862e-77	267.0	COG2237@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG02929@2157|Archaea,arCOG04151@2157|Archaea,41SHN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158380_k127_2230396_18	1459636.NTE_01664	6.696e-21	97.0	COG1310@1|root,arCOG01138@2157|Archaea,41SSV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158380_k127_2230396_1	1459636.NTE_01665	1.651e-175	559.0	COG0017@1|root,arCOG00406@2157|Archaea,41S93@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_2230396_11	1459636.NTE_01666	1.383e-41	158.0	COG0195@1|root,arCOG01761@2157|Archaea,41T4Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2230396_5	1459636.NTE_01674	2.297e-85	290.0	COG0444@1|root,arCOG00181@2157|Archaea,41S9V@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_2230396_9	1459636.NTE_02647	4.156e-48	176.0	COG1051@1|root,arCOG01075@2157|Archaea	2157|Archaea	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158380_k127_2230396_0	1459636.NTE_02652	8.842e-183	579.0	COG0520@1|root,arCOG00065@2157|Archaea,41SCV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158380_k127_2230396_8	1459636.NTE_02653	1.934e-66	228.0	COG0822@1|root,arCOG02077@2157|Archaea,41SPT@651137|Thaumarchaeota	651137|Thaumarchaeota	C	SUF system FeS assembly protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158380_k127_2230396_19	1459636.NTE_02656	4.248e-11	67.0	arCOG08761@1|root,arCOG08761@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2230396_10	1459636.NTE_02655	7.856e-43	166.0	COG0671@1|root,arCOG03056@2157|Archaea,41SQ8@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158380_k127_2231393_15	880073.Calab_1297	0.000729	44.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	rssB	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158380_k127_2231393_14	436308.Nmar_1305	1.91e-07	59.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2231393_7	1459636.NTE_00521	2.395e-57	212.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158380_k127_2231393_8	1459636.NTE_01410	2.051e-52	190.0	COG1628@1|root,arCOG00928@2157|Archaea,41SMQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
SRR25158380_k127_2231393_3	1459636.NTE_00844	2.469e-89	299.0	COG1335@1|root,arCOG01943@2157|Archaea	2157|Archaea	Q	COG1335 Amidases related to nicotinamidase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158380_k127_2231393_1	1459636.NTE_02481	6.314e-171	553.0	COG0034@1|root,COG0367@1|root,arCOG00071@2157|Archaea,arCOG00093@2157|Archaea	2157|Archaea	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	asnB	-	6.3.1.14,6.3.5.4	ko:K01953,ko:K06927	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578,R03613	RC00010,RC00358	ko00000,ko00001,ko01000,ko01002,ko03012	-	-	-	Asn_synthase,GATase_6,GATase_7
SRR25158380_k127_2231393_10	82654.Pse7367_0514	2.723e-15	84.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
SRR25158380_k127_2231393_5	1459636.NTE_01903	4.638e-73	250.0	COG3620@1|root,arCOG00608@2157|Archaea,41SJR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_3
SRR25158380_k127_2231393_0	1459636.NTE_01902	8.048e-206	647.0	COG1503@1|root,arCOG01742@2157|Archaea,41SEK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
SRR25158380_k127_2231393_2	1459636.NTE_01761	6.074e-137	440.0	COG1032@1|root,arCOG01363@2157|Archaea,41S6P@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_2231393_6	246197.MXAN_3479	2.26e-63	231.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2231393_13	1459636.NTE_01760	6.533e-08	59.0	COG1369@1|root,arCOG01365@2157|Archaea	2157|Archaea	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp2	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03537	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	RNase_P_Rpp14
SRR25158380_k127_2231393_9	1459636.NTE_01758	1.267e-19	95.0	COG1325@1|root,arCOG01042@2157|Archaea,41SWK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA binding	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
SRR25158380_k127_2231393_4	1459636.NTE_01757	1.618e-74	256.0	COG1890@1|root,arCOG04186@2157|Archaea,41SM9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	-	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
SRR25158380_k127_2244376_1	247490.KSU1_D0999	3.878e-27	125.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_2244376_0	1459636.NTE_01057	1.895e-129	428.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
SRR25158380_k127_2244469_0	525904.Tter_1369	4.171e-36	143.0	COG0387@1|root,COG0387@2|Bacteria,2NQA1@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	cax	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iJN678.slr1336	Na_Ca_ex
SRR25158380_k127_2247858_5	1459636.NTE_02136	2.155e-15	78.0	arCOG12348@1|root,arCOG12348@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2247858_4	1459636.NTE_00881	2.46e-21	99.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_2247858_0	118168.MC7420_7123	8.923e-71	246.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria,1H91U@1150|Oscillatoriales	1117|Cyanobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_2247858_1	1048834.TC41_0139	4.971e-66	241.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158380_k127_2247858_3	1459636.NTE_00644	2.563e-45	169.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2247858_2	1403313.AXBR01000023_gene2644	8.266e-62	222.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZD11@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158380_k127_2248984_0	1459636.NTE_00043	9.179e-121	392.0	COG1117@1|root,arCOG00231@2157|Archaea,41SYJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158380_k127_2248984_1	1459636.NTE_02295	7.922e-88	297.0	COG2897@1|root,arCOG02019@2157|Archaea,41SXR@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_2248984_2	1459636.NTE_03156	3.004e-77	270.0	COG0677@1|root,arCOG00252@2157|Archaea	2157|Archaea	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	NAD_binding_2,UDPG_MGDP_dh,UDPG_MGDP_dh_C
SRR25158380_k127_2248984_3	1459636.NTE_01294	2.528e-48	181.0	COG0586@1|root,arCOG03117@2157|Archaea,41SQ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_2259313_1	1459636.NTE_02333	2.774e-15	79.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2259313_0	443144.GM21_2393	2.105e-22	109.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2266568_0	1094980.Mpsy_0997	9.068e-59	229.0	COG0683@1|root,arCOG01021@2157|Archaea,2Y6Q1@28890|Euryarchaeota,2NAW8@224756|Methanomicrobia	224756|Methanomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158380_k127_2266878_1	1459636.NTE_00138	2.088e-39	151.0	COG0463@1|root,arCOG00894@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_2266878_2	644281.MFS40622_1531	4.835e-23	104.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2266878_3	797299.HALLA_08105	3.298e-21	99.0	COG0529@1|root,arCOG01040@2157|Archaea,2XWW4@28890|Euryarchaeota,23V8B@183963|Halobacteria	183963|Halobacteria	P	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
SRR25158380_k127_2266878_0	795359.TOPB45_1395	3.821e-60	220.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GGVI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
SRR25158380_k127_228358_1	1131266.ARWQ01000001_gene1353	2.225e-41	158.0	COG1514@1|root,arCOG01736@2157|Archaea,41SP7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158380_k127_228358_0	1229909.NSED_09545	1.543e-65	234.0	COG1746@1|root,arCOG04249@2157|Archaea,41S76@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
SRR25158380_k127_2283963_0	1459636.NTE_02897	1.341e-106	353.0	COG1475@1|root,arCOG11113@2157|Archaea,41SYF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158380_k127_2283963_2	1131553.JIBI01000009_gene1208	6.175e-72	252.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2VK89@28216|Betaproteobacteria,372S3@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ABC 3 transport family	mntB	-	-	ko:K02075,ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158380_k127_2283963_3	1173022.Cri9333_3290	6.572e-60	215.0	COG1121@1|root,COG1121@2|Bacteria,1G2EJ@1117|Cyanobacteria,1HEKF@1150|Oscillatoriales	1117|Cyanobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158380_k127_2283963_1	316274.Haur_2846	7.412e-98	330.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158380_k127_2285951_2	436308.Nmar_0978	3.905e-29	121.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158380_k127_2285951_0	1131266.ARWQ01000004_gene1476	2.395e-82	282.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_2285951_1	1459636.NTE_01334	2.144e-41	154.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_2286453_35	521011.Mpal_1345	6.107e-27	117.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_2286453_39	1459636.NTE_03327	5.846e-22	102.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2286453_36	1131266.ARWQ01000005_gene797	2.722e-23	104.0	COG1522@1|root,arCOG04153@2157|Archaea,41SP6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2286453_34	1459636.NTE_02714	3.342e-27	117.0	arCOG03788@1|root,arCOG03788@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR25158380_k127_2286453_30	1459636.NTE_02715	2.672e-40	154.0	COG5615@1|root,arCOG05392@2157|Archaea,41T4B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
SRR25158380_k127_2286453_2	1459636.NTE_01316	3.472e-241	752.0	COG3425@1|root,arCOG01767@2157|Archaea,41SAQ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
SRR25158380_k127_2286453_8	1459636.NTE_00788	4.763e-168	535.0	COG1060@1|root,arCOG00656@2157|Archaea,41SCN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_2286453_6	1459636.NTE_00789	6.441e-176	557.0	COG1060@1|root,arCOG00656@2157|Archaea,41SEG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_2286453_16	1459636.NTE_00799	4.291e-96	321.0	COG2107@1|root,arCOG00654@2157|Archaea,41SB8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158380_k127_2286453_38	1459636.NTE_01532	5.678e-22	98.0	arCOG08750@1|root,arCOG08750@2157|Archaea	1459636.NTE_01532|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2286453_20	1459636.NTE_01228	3.69e-75	258.0	COG0311@1|root,arCOG00034@2157|Archaea,41SIZ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158380_k127_2286453_9	1459636.NTE_01229	8.852e-161	511.0	COG0214@1|root,arCOG04075@2157|Archaea,41SEJ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158380_k127_2286453_1	1459636.NTE_01233	4.41e-242	764.0	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158380_k127_2286453_14	930945.SiRe_2457	8.828e-117	383.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158380_k127_2286453_13	1459636.NTE_00961	2.328e-130	417.0	arCOG08676@1|root,arCOG08676@2157|Archaea,41SCF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Archaeal ammonia monooxygenase subunit A (AmoA)	-	-	1.14.18.3,1.14.99.39	ko:K10944	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Archaeal_AmoA
SRR25158380_k127_2286453_29	1459636.NTE_00962	5.806e-41	152.0	arCOG10586@1|root,arCOG10586@2157|Archaea,41STH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2286453_21	1459636.NTE_01090	3.271e-71	246.0	arCOG08675@1|root,arCOG08675@2157|Archaea,41SI5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Monooxygenase subunit B protein	-	-	-	ko:K10945	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	Monooxygenase_B
SRR25158380_k127_2286453_31	1459636.NTE_01751	1.05e-39	149.0	arCOG08672@1|root,arCOG08672@2157|Archaea,41SU2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2286453_24	1459636.NTE_01753	3.654e-62	217.0	COG0184@1|root,arCOG04185@2157|Archaea,41SKP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
SRR25158380_k127_2286453_18	1459636.NTE_01754	7.817e-84	295.0	COG0608@1|root,arCOG00427@2157|Archaea,41SZF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
SRR25158380_k127_2286453_7	1459636.NTE_01756	1.805e-170	544.0	COG0172@1|root,arCOG00403@2157|Archaea,41SC9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158380_k127_2286453_28	1459636.NTE_01767	5.91e-47	174.0	COG0537@1|root,arCOG00419@2157|Archaea,41SNV@651137|Thaumarchaeota	651137|Thaumarchaeota	F	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158380_k127_2286453_0	1459636.NTE_01783	5.623e-282	874.0	COG0129@1|root,arCOG04045@2157|Archaea,41SD0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158380_k127_2286453_12	1459636.NTE_00744	1.132e-144	466.0	COG0657@1|root,arCOG02638@2157|Archaea	2157|Archaea	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K01066,ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158380_k127_2286453_27	204669.Acid345_0211	3.986e-49	184.0	COG4221@1|root,COG4221@2|Bacteria,3Y6ZB@57723|Acidobacteria,2JKUG@204432|Acidobacteriia	204432|Acidobacteriia	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_2286453_42	373903.Hore_07040	1.482e-09	61.0	COG3360@1|root,COG3360@2|Bacteria,1VF2X@1239|Firmicutes,24QS4@186801|Clostridia	186801|Clostridia	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158380_k127_2286453_17	1459636.NTE_03312	3.83e-95	319.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	aknG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158380_k127_2286453_33	1459636.NTE_03311	9.139e-37	139.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2286453_23	1459636.NTE_03310	4.497e-63	216.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_2286453_32	1459636.NTE_03303	6.868e-37	146.0	COG1936@1|root,arCOG01038@2157|Archaea,41SPH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
SRR25158380_k127_2286453_25	1459636.NTE_03306	1.162e-57	204.0	COG1958@1|root,arCOG00999@2157|Archaea	2157|Archaea	K	PFAM Like-Sm ribonucleoprotein, core	-	-	-	-	-	-	-	-	-	-	-	-	LSM,Lsm_C,SM-ATX
SRR25158380_k127_2286453_5	1459636.NTE_03307	1.173e-197	629.0	COG0343@1|root,arCOG00989@2157|Archaea,41SF4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	-	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158380_k127_2286453_22	1459636.NTE_02327	1.224e-69	242.0	COG0066@1|root,arCOG02230@2157|Archaea,41T1U@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158380_k127_2286453_3	1459636.NTE_02326	3.472e-237	741.0	COG0065@1|root,arCOG01698@2157|Archaea,41SYT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, large subunit	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158380_k127_2286453_15	1459636.NTE_02325	3.457e-113	368.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158380_k127_2286453_10	1131266.ARWQ01000001_gene1220	7.571e-156	504.0	COG0476@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG01676@2157|Archaea,41S5X@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS
SRR25158380_k127_2286453_4	1459636.NTE_00076	1.037e-203	639.0	COG0498@1|root,arCOG01434@2157|Archaea,41SEI@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2286453_26	1459636.NTE_00075	4.289e-51	183.0	COG0139@1|root,arCOG02676@2157|Archaea,41SPE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158380_k127_2286453_11	1459636.NTE_00071	3.564e-153	496.0	COG1571@1|root,arCOG01115@2157|Archaea,41S9G@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	-	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743
SRR25158380_k127_2286453_19	1459636.NTE_00015	4.211e-81	275.0	COG1976@1|root,arCOG04176@2157|Archaea,41SIP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
SRR25158380_k127_2292207_1	1131266.ARWQ01000004_gene1493	1.989e-84	287.0	COG0543@1|root,arCOG02199@2157|Archaea,41SY5@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SRR25158380_k127_2292207_0	436308.Nmar_1390	1.425e-103	345.0	COG0167@1|root,arCOG00603@2157|Archaea	2157|Archaea	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R01868,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158380_k127_2300667_1	1459636.NTE_02637	1.405e-55	207.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158380_k127_2300667_3	869210.Marky_1870	5.793e-30	130.0	COG1587@1|root,COG1587@2|Bacteria,1WJ52@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRR25158380_k127_2300667_2	929712.KI912613_gene2241	2.126e-46	175.0	COG1409@1|root,COG3511@1|root,COG1409@2|Bacteria,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4CTVZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Phosphoesterase
SRR25158380_k127_2300667_0	485913.Krac_2159	6.927e-117	384.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	acpA	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158380_k127_2308781_0	1459636.NTE_03464	9.435e-85	296.0	COG1752@1|root,arCOG09020@2157|Archaea	2157|Archaea	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158380_k127_2308781_1	1459636.NTE_01743	1.149e-38	148.0	COG0346@1|root,arCOG03101@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_230944_1	1459636.NTE_02704	1.647e-24	104.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2309996_0	1459636.NTE_02873	4.53e-90	303.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_2309996_2	1459636.NTE_02296	7.013e-42	166.0	arCOG00059@1|root,arCOG00059@2157|Archaea,41T4Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2309996_1	1459636.NTE_00416	1.938e-44	167.0	COG0484@1|root,COG1141@1|root,arCOG00349@2157|Archaea,arCOG02846@2157|Archaea,41ST0@651137|Thaumarchaeota	651137|Thaumarchaeota	CO	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Fer4_13
SRR25158380_k127_2311212_0	1459636.NTE_01444	9.144e-217	685.0	COG1351@1|root,arCOG01884@2157|Archaea,41SF6@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158380_k127_2311212_2	1459636.NTE_01612	1.114e-132	430.0	COG0258@1|root,arCOG04050@2157|Archaea,41SBU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
SRR25158380_k127_2311212_3	517417.Cpar_1355	5.056e-73	262.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
SRR25158380_k127_2311212_1	1459636.NTE_01317	5.974e-155	499.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2311212_8	1123511.KB905840_gene805	3.052e-18	90.0	COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4H7ZV@909932|Negativicutes	909932|Negativicutes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158380_k127_2311212_9	436308.Nmar_1439	1.404e-13	72.0	COG0346@1|root,arCOG02706@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158380_k127_2311212_11	369723.Strop_1956	2.322e-08	58.0	COG0346@1|root,COG0346@2|Bacteria	369723.Strop_1956|-	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2311212_7	1459636.NTE_01297	6.067e-22	99.0	COG0011@1|root,arCOG04373@2157|Archaea,41T99@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
SRR25158380_k127_2311212_5	1459636.NTE_02704	9.519e-29	115.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2311212_10	273116.14325504	9.8e-09	58.0	COG5466@1|root,arCOG05278@2157|Archaea,2Y5U3@28890|Euryarchaeota,242H8@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158380_k127_2319246_4	525904.Tter_0425	4.867e-24	105.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_2319246_2	1459636.NTE_00092	7.101e-92	311.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	1459636.NTE_00092|-	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158380_k127_2319246_5	1459636.NTE_00408	8.93e-22	97.0	arCOG08700@1|root,arCOG08700@2157|Archaea,41SV2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2319246_1	1459636.NTE_01409	3.304e-92	313.0	COG3276@1|root,arCOG01564@2157|Archaea,41SCR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	elongation factor Tu	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
SRR25158380_k127_2319246_0	693661.Arcve_0993	2.927e-235	756.0	COG0383@1|root,arCOG03661@2157|Archaea,2XVNX@28890|Euryarchaeota	28890|Euryarchaeota	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158380_k127_2319246_3	693661.Arcve_0994	1.608e-49	187.0	COG3769@1|root,arCOG01215@2157|Archaea,2XZBT@28890|Euryarchaeota	28890|Euryarchaeota	S	Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG)	mngB	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158380_k127_2326145_0	1459636.NTE_02841	9.53e-54	202.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41T50@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2326145_1	1459636.NTE_03327	3.73e-30	128.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_235077_23	1459636.NTE_01811	8.996e-23	107.0	arCOG08721@1|root,arCOG08721@2157|Archaea,41SRS@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_235077_21	1459636.NTE_01812	8.977e-26	111.0	arCOG08709@1|root,arCOG08709@2157|Archaea,41T5B@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_235077_17	1459636.NTE_01817	9.301e-50	179.0	arCOG11395@1|root,arCOG11395@2157|Archaea,41TBH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_235077_27	1459636.NTE_01816	1.135e-08	62.0	COG1545@1|root,arCOG01289@2157|Archaea,41SWD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_235077_3	1459636.NTE_01815	3.724e-104	350.0	COG0183@1|root,arCOG01278@2157|Archaea,41SB7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_235077_2	1459636.NTE_01814	1.807e-112	372.0	COG2141@1|root,arCOG02410@2157|Archaea,41SC0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_235077_6	1459636.NTE_01813	1.067e-91	306.0	COG1208@1|root,arCOG00663@2157|Archaea,41SIU@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR25158380_k127_235077_13	1459636.NTE_01821	1.908e-67	233.0	COG0097@1|root,arCOG04090@2157|Archaea,41SJG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158380_k127_235077_14	1459636.NTE_01822	3.21e-66	227.0	COG0096@1|root,arCOG04091@2157|Archaea,41SMM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158380_k127_235077_20	1459636.NTE_01823	3.612e-26	108.0	COG0199@1|root,arCOG00782@2157|Archaea,41SW8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158380_k127_235077_12	1459636.NTE_01824	3.604e-68	235.0	COG0094@1|root,arCOG04092@2157|Archaea,41SJP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158380_k127_235077_11	1459636.NTE_01825	8.994e-70	243.0	COG1471@1|root,arCOG04093@2157|Archaea,41SIE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
SRR25158380_k127_235077_22	1459636.NTE_01826	1.849e-24	109.0	COG0198@1|root,arCOG04094@2157|Archaea,41SSS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L26
SRR25158380_k127_235077_9	1459636.NTE_01827	1.992e-74	252.0	COG0093@1|root,arCOG04095@2157|Archaea,41SHG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158380_k127_235077_18	1459636.NTE_01828	5.489e-43	159.0	COG0186@1|root,arCOG04096@2157|Archaea,41SSH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158380_k127_235077_26	579137.Metvu_0223	6.811e-09	60.0	COG1588@1|root,arCOG00784@2157|Archaea,2Y0EN@28890|Euryarchaeota,23R70@183939|Methanococci	183939|Methanococci	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
SRR25158380_k127_235077_25	1459636.NTE_01830	5.006e-20	91.0	COG0255@1|root,arCOG00785@2157|Archaea,41SV8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uL29 family	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158380_k127_235077_7	1459636.NTE_01831	2.538e-87	296.0	COG0092@1|root,arCOG04097@2157|Archaea,41SIM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds the lower part of the 30S subunit head	rps3	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158380_k127_235077_10	1459636.NTE_01832	1.925e-73	249.0	COG0091@1|root,arCOG04098@2157|Archaea,41SJ4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158380_k127_235077_15	1459636.NTE_01833	4.808e-65	225.0	COG0185@1|root,arCOG04099@2157|Archaea,41SMH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158380_k127_235077_24	1459636.NTE_01834	5.639e-22	98.0	COG0089@1|root,arCOG04072@2157|Archaea,41SS4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome	rpl23	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158380_k127_235077_4	1459636.NTE_01835	3.663e-93	312.0	COG0469@1|root,arCOG04071@2157|Archaea,41SHB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L4	-	-	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158380_k127_235077_0	1459636.NTE_01836	1.407e-142	459.0	COG0087@1|root,arCOG04070@2157|Archaea,41SDN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein L3	-	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158380_k127_235077_16	1459636.NTE_01837	1.698e-61	222.0	COG2106@1|root,arCOG04069@2157|Archaea,41SI7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative RNA methyltransferase	-	-	-	ko:K09142	-	-	-	-	ko00000	-	-	-	Methyltrn_RNA_3
SRR25158380_k127_235077_8	1459636.NTE_01838	2.486e-81	277.0	arCOG08717@1|root,arCOG08717@2157|Archaea,41SFQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_235077_1	1459636.NTE_01839	1.15e-114	374.0	COG0638@1|root,arCOG00971@2157|Archaea,41SYA@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Proteasome endopeptidase complex	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
SRR25158380_k127_235077_19	1459636.NTE_01841	5.207e-37	144.0	COG2090@1|root,arCOG04171@2157|Archaea,41SNF@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF371)	-	-	-	ko:K09738	-	-	-	-	ko00000	-	-	-	DUF371
SRR25158380_k127_235077_5	1459636.NTE_01843	6.025e-93	313.0	COG0152@1|root,arCOG04421@2157|Archaea,41SAR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158380_k127_235077_28	1459636.NTE_02000	0.0001527	46.0	COG0842@1|root,arCOG01469@2157|Archaea	2157|Archaea	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158380_k127_2351645_0	1459636.NTE_02122	1.648e-119	394.0	COG1744@1|root,arCOG00257@2157|Archaea	2157|Archaea	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
SRR25158380_k127_2351645_1	1459636.NTE_01496	4.115e-83	285.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_2352949_1	1459636.NTE_02407	7.164e-252	795.0	COG1331@1|root,arCOG02007@2157|Archaea,41SHZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158380_k127_2352949_11	1459636.NTE_00907	8.17e-05	47.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K03294,ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6,2.A.3.2	-	-	Usp
SRR25158380_k127_2352949_4	1459636.NTE_00842	2.965e-123	402.0	COG0613@1|root,arCOG00302@2157|Archaea,41S5J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
SRR25158380_k127_2352949_5	1459636.NTE_03013	1.205e-111	367.0	COG2519@1|root,arCOG00978@2157|Archaea,41SEF@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
SRR25158380_k127_2352949_3	1459636.NTE_03016	6.126e-172	560.0	COG0018@1|root,arCOG00487@2157|Archaea,41SAI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158380_k127_2352949_8	1459636.NTE_03017	8.939e-88	295.0	COG0561@1|root,arCOG01213@2157|Archaea,41SIV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Phosphoglycolate phosphatase	-	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158380_k127_2352949_2	1459636.NTE_01993	6.594e-233	728.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
SRR25158380_k127_2352949_0	1459636.NTE_01994	5.435e-268	843.0	COG0046@1|root,arCOG00641@2157|Archaea,41S6S@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_2352949_7	1459636.NTE_01995	1.015e-90	303.0	COG0047@1|root,arCOG00102@2157|Archaea,41SG3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158380_k127_2352949_9	1459636.NTE_01996	1.509e-44	166.0	COG0517@1|root,arCOG00606@2157|Archaea,41SRY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2352949_10	1459636.NTE_01997	1.045e-21	99.0	COG1828@1|root,arCOG04462@2157|Archaea,41STY@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158380_k127_2352949_6	1459636.NTE_02000	2.409e-99	329.0	COG0842@1|root,arCOG01469@2157|Archaea	2157|Archaea	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158380_k127_2383854_4	1229909.NSED_08795	3.467e-18	88.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158380_k127_2383854_3	1459636.NTE_01477	1.558e-32	130.0	COG1970@1|root,arCOG05213@2157|Archaea	2157|Archaea	M	Large-conductance mechanosensitive channel, MscL	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158380_k127_2383854_5	436308.Nmar_1649	0.0004976	51.0	arCOG10597@1|root,arCOG10597@2157|Archaea	2157|Archaea	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2383854_1	1459636.NTE_01122	1.008e-57	205.0	COG0783@1|root,arCOG01101@2157|Archaea	2157|Archaea	P	Belongs to the Dps family	frt	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR25158380_k127_2383854_2	697282.Mettu_0258	3.669e-43	165.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1XG99@135618|Methylococcales	135618|Methylococcales	C	Belongs to the WrbA family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158380_k127_2383854_0	228410.NE0564	6.343e-254	811.0	COG2132@1|root,COG3391@1|root,COG3794@1|root,COG2132@2|Bacteria,COG3391@2|Bacteria,COG3794@2|Bacteria,1PE86@1224|Proteobacteria,2W9VS@28216|Betaproteobacteria,3720H@32003|Nitrosomonadales	28216|Betaproteobacteria	CQ	Multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Lactonase
SRR25158380_k127_2390631_1	1459636.NTE_02416	1.224e-32	135.0	COG0671@1|root,arCOG03056@2157|Archaea	2157|Archaea	I	PFAM phosphoesterase, PA-phosphatase related	sepP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158380_k127_2390631_2	1459636.NTE_00422	4.966e-22	96.0	arCOG08799@1|root,arCOG08799@2157|Archaea,41T6M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2390631_0	1459636.NTE_03244	1.369e-68	245.0	COG1237@1|root,arCOG00503@2157|Archaea	2157|Archaea	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158380_k127_2390799_0	1459636.NTE_00785	2.801e-08	60.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2391301_0	926549.KI421517_gene2554	3.611e-97	325.0	COG4294@1|root,COG4294@2|Bacteria,4NIZA@976|Bacteroidetes,47K7P@768503|Cytophagia	976|Bacteroidetes	L	UV-endonuclease UvdE	-	-	-	-	-	-	-	-	-	-	-	-	UvdE
SRR25158380_k127_2391301_2	555088.DealDRAFT_1277	2.949e-27	114.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,24M30@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158380_k127_2391301_3	1459636.NTE_00230	2.268e-11	68.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158380_k127_2391301_1	1089547.KB913013_gene4432	8.46e-28	117.0	COG1145@1|root,32SB1@2|Bacteria,4NQ8P@976|Bacteroidetes,47S5U@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158380_k127_2392478_1	1459636.NTE_01103	1.689e-75	280.0	COG1361@1|root,arCOG02080@2157|Archaea,41T6N@651137|Thaumarchaeota	651137|Thaumarchaeota	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2392478_0	1459636.NTE_01102	4.812e-135	441.0	COG0577@1|root,arCOG02312@2157|Archaea,41T94@651137|Thaumarchaeota	2157|Archaea	V	ABC-type transport system, involved in lipoprotein release, permease component	abcS-2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158380_k127_2392801_0	70601.3257448	6.948e-19	92.0	COG1673@1|root,arCOG02727@2157|Archaea,2XX5V@28890|Euryarchaeota,2443M@183968|Thermococci	183968|Thermococci	S	Belongs to the UPF0310 family	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR25158380_k127_2392801_1	319225.Plut_0889	1.078e-06	52.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158380_k127_2396033_0	323848.Nmul_A2094	3.383e-20	91.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,372XI@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158380_k127_2396033_1	1459636.NTE_02321	4.313e-15	78.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_23994_1	1459636.NTE_02862	1.054e-118	399.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_23994_0	1459636.NTE_02677	2.435e-122	403.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_23994_2	1459636.NTE_02673	1.391e-47	173.0	arCOG01449@1|root,arCOG01449@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2400935_0	1459636.NTE_03337	1.131e-35	138.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_2406926_0	1459636.NTE_01052	1.943e-88	325.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_2406926_1	1459636.NTE_01458	5.161e-27	114.0	arCOG10549@1|root,arCOG10549@2157|Archaea	1459636.NTE_01458|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2414590_1	1459636.NTE_01476	9.925e-66	233.0	COG0120@1|root,arCOG01122@2157|Archaea,41SJE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Ribose 5-phosphate isomerase	-	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158380_k127_2414590_0	1459636.NTE_01478	5.118e-177	569.0	COG0044@1|root,arCOG00689@2157|Archaea,41S8A@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158380_k127_2414590_3	1459636.NTE_01663	7.368e-18	94.0	COG2237@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG02929@2157|Archaea,arCOG04151@2157|Archaea,41SHN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158380_k127_2414590_2	1459636.NTE_01403	5.477e-42	166.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
SRR25158380_k127_2418558_27	153721.MYP_4858	5.767e-18	97.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
SRR25158380_k127_2418558_16	436308.Nmar_0119	1.051e-56	212.0	COG2244@1|root,arCOG02209@2157|Archaea,41T3C@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2418558_17	521011.Mpal_0585	5.154e-52	190.0	COG2120@1|root,arCOG03460@2157|Archaea,2XU80@28890|Euryarchaeota,2NAKP@224756|Methanomicrobia	224756|Methanomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158380_k127_2418558_18	1131266.ARWQ01000002_gene480	1.764e-49	183.0	COG0558@1|root,arCOG00670@2157|Archaea,41SJ7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
SRR25158380_k127_2418558_19	1459636.NTE_01923	6.325e-46	168.0	COG4830@1|root,arCOG04305@2157|Archaea,41SNM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02976	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S26e
SRR25158380_k127_2418558_6	1459636.NTE_01921	2.776e-142	458.0	COG0061@1|root,COG0640@1|root,arCOG00394@2157|Archaea,arCOG01348@2157|Archaea,41SEC@651137|Thaumarchaeota	651137|Thaumarchaeota	HK	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158380_k127_2418558_0	1459636.NTE_01920	2.509e-248	776.0	COG0504@1|root,arCOG00063@2157|Archaea,41S7G@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158380_k127_2418558_12	1459636.NTE_02123	5.353e-116	395.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158380_k127_2418558_21	1459636.NTE_01350	7.295e-30	124.0	COG1439@1|root,arCOG00721@2157|Archaea,41SPQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PIN domain of ribonuclease	-	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
SRR25158380_k127_2418558_14	1459636.NTE_01351	3.477e-78	269.0	COG0061@1|root,arCOG01348@2157|Archaea,41SHP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158380_k127_2418558_26	439481.Aboo_0440	4.181e-19	101.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota,3F33E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpD
SRR25158380_k127_2418558_13	1459636.NTE_01580	1.725e-108	362.0	COG1798@1|root,COG1849@1|root,arCOG01224@2157|Archaea,arCOG04161@2157|Archaea,41SC2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	diphthine synthase	-	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	DUF357,TP_methylase
SRR25158380_k127_2418558_5	1459636.NTE_01581	8.506e-177	560.0	COG0624@1|root,arCOG01107@2157|Archaea,41SAX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_2418558_9	1459636.NTE_01582	5.357e-128	415.0	COG0189@1|root,arCOG01589@2157|Archaea,41SE8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
SRR25158380_k127_2418558_23	1459636.NTE_01583	1.017e-22	97.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41STK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158380_k127_2418558_1	1459636.NTE_01584	7.254e-214	670.0	COG0119@1|root,arCOG02092@2157|Archaea,41S7Y@651137|Thaumarchaeota	651137|Thaumarchaeota	E	HMGL-like	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158380_k127_2418558_20	1229909.NSED_07170	2.34e-39	151.0	COG1522@1|root,arCOG01580@2157|Archaea,41SNE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158380_k127_2418558_4	1459636.NTE_00736	1.228e-187	592.0	COG4992@1|root,arCOG00914@2157|Archaea,41SC8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_2418558_10	1459636.NTE_00735	1.818e-121	394.0	COG0548@1|root,arCOG00862@2157|Archaea,41SFB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis)	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158380_k127_2418558_2	1459636.NTE_00734	5.303e-197	617.0	COG0002@1|root,arCOG00495@2157|Archaea,41S8R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158380_k127_2418558_11	1459636.NTE_00733	6.453e-117	382.0	COG0189@1|root,arCOG01589@2157|Archaea,41SCQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
SRR25158380_k127_2418558_25	1459636.NTE_00732	7.758e-20	90.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41SVX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158380_k127_2418558_3	1459636.NTE_00731	3.469e-188	595.0	COG0137@1|root,arCOG00112@2157|Archaea,41S6K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158380_k127_2418558_15	1459636.NTE_00729	1.182e-62	226.0	COG5012@1|root,arCOG03932@1|root,arCOG03402@2157|Archaea,arCOG03932@2157|Archaea,41SKB@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2418558_22	1122915.AUGY01000020_gene6450	1.276e-24	113.0	COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,4HC31@91061|Bacilli,26Z0E@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158380_k127_2418558_8	237368.SCABRO_00224	4.217e-134	440.0	COG1524@1|root,COG1524@2|Bacteria,2IXT6@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158380_k127_2418558_24	1405.DJ92_4756	2.188e-20	102.0	COG0382@1|root,COG0382@2|Bacteria,1UZUK@1239|Firmicutes,4HDQ2@91061|Bacilli	91061|Bacilli	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158380_k127_2418558_7	221288.JH992901_gene3607	4.512e-141	454.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1JIY9@1189|Stigonemataceae	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_2419963_2	1459636.NTE_00894	7.803e-28	119.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Ribosomal_S30AE
SRR25158380_k127_2419963_0	1459636.NTE_03520	6.402e-58	211.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2419963_3	1459636.NTE_01962	6.378e-09	60.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2419963_4	436308.Nmar_1669	0.0007648	49.0	arCOG08825@1|root,arCOG08825@2157|Archaea,41T1X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2419963_1	1459636.NTE_00597	2.004e-48	177.0	COG3945@1|root,arCOG01471@2157|Archaea,41T45@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158380_k127_2443245_2	1459636.NTE_01494	1.015e-15	78.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01494|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2443245_0	1459636.NTE_01927	2.193e-110	376.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158380_k127_2443245_3	253839.SSNG_00242	1.297e-13	78.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,SLH
SRR25158380_k127_2456_0	1121324.CLIT_2c02800	1.795e-47	178.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin-like,Lactonase,PKD,TIG
SRR25158380_k127_2483613_2	1459636.NTE_01575	1.1e-26	113.0	arCOG08633@1|root,arCOG08633@2157|Archaea,41SUK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2483613_1	1459636.NTE_03525	1.742e-48	178.0	COG3794@1|root,arCOG02926@2157|Archaea,41SPG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158380_k127_2483613_0	1459636.NTE_01577	3.109e-249	777.0	COG1290@1|root,arCOG01721@2157|Archaea,41SDA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR25158380_k127_2483613_3	309800.C498_08555	1.71e-08	63.0	COG0723@1|root,arCOG01720@2157|Archaea,2XUXF@28890|Euryarchaeota,23U4Y@183963|Halobacteria	183963|Halobacteria	C	COG0723 Rieske Fe-S protein	-	-	-	ko:K15878	-	-	-	-	ko00000	-	-	-	Rieske
SRR25158380_k127_2509_1	1459636.NTE_01352	5.604e-109	361.0	COG2897@1|root,arCOG02019@2157|Archaea,41SZQ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_2509_0	1459636.NTE_01035	1.261e-114	379.0	COG0640@1|root,COG1809@1|root,arCOG00394@2157|Archaea,arCOG04896@2157|Archaea	2157|Archaea	K	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158380_k127_2568986_0	1459636.NTE_01087	0.0	1058.0	COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_2568986_6	1459636.NTE_02437	3.28e-22	97.0	COG1552@1|root,arCOG04049@2157|Archaea,41T87@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL40 family	-	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
SRR25158380_k127_2568986_3	1459636.NTE_03057	8.666e-61	215.0	COG0237@1|root,arCOG01045@2157|Archaea,41SI8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17
SRR25158380_k127_2568986_5	1459636.NTE_03058	4.743e-31	126.0	COG1931@1|root,arCOG01043@2157|Archaea,41SRJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0201 family	-	-	-	ko:K09736	-	-	-	-	ko00000	-	-	-	RNA_binding
SRR25158380_k127_2568986_2	1459636.NTE_01328	2.374e-89	298.0	COG0778@1|root,arCOG00288@2157|Archaea,41T1J@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_2568986_7	1459636.NTE_01445	8.844e-19	92.0	arCOG08754@1|root,arCOG08754@2157|Archaea,41SUV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2568986_9	1229909.NSED_05710	1.431e-07	60.0	arCOG06343@1|root,arCOG06343@2157|Archaea,41SRX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
SRR25158380_k127_2568986_1	1459636.NTE_01626	4.461e-148	477.0	COG3243@1|root,arCOG06344@2157|Archaea,41SEX@651137|Thaumarchaeota	651137|Thaumarchaeota	I	TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158380_k127_2568986_4	1459636.NTE_00560	6.341e-34	134.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2568986_8	1459636.NTE_00367	3.57e-17	86.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_00367|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2569451_0	1123386.AUIW01000011_gene1923	4.137e-70	259.0	COG0433@1|root,COG0433@2|Bacteria,1WME2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2570579_4	1459636.NTE_02126	1.873e-29	119.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
SRR25158380_k127_2570579_2	1459636.NTE_03018	6.846e-70	241.0	COG0221@1|root,arCOG01711@2157|Archaea,41T3F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158380_k127_2570579_0	1459636.NTE_03020	1.839e-192	607.0	COG0464@1|root,arCOG01307@2157|Archaea,41SA4@651137|Thaumarchaeota	651137|Thaumarchaeota	D	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,MIT,Vps4_C
SRR25158380_k127_2570579_1	1459636.NTE_01454	1.749e-137	449.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158380_k127_2570579_3	1459636.NTE_01455	1.561e-53	192.0	COG2042@1|root,arCOG04733@2157|Archaea,41SMC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ribosome biogenesis protein, C-terminal	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
SRR25158380_k127_2570579_5	679926.Mpet_2045	4.79e-06	55.0	COG0582@1|root,arCOG01242@2157|Archaea,2Y83U@28890|Euryarchaeota,2NAAN@224756|Methanomicrobia	224756|Methanomicrobia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158380_k127_2575508_0	1459636.NTE_01509	3.758e-38	155.0	arCOG02362@1|root,arCOG02362@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
SRR25158380_k127_2582050_7	1459636.NTE_00429	3.086e-10	66.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2582050_3	1459636.NTE_01254	1.15e-78	265.0	COG0066@1|root,arCOG02230@2157|Archaea,41SIA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158380_k127_2582050_0	1459636.NTE_01255	5.014e-223	696.0	COG0065@1|root,arCOG01698@2157|Archaea,41S7A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158380_k127_2582050_2	1459636.NTE_01256	2.595e-83	283.0	COG1478@1|root,arCOG02714@2157|Archaea,41SHA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
SRR25158380_k127_2582050_4	1459636.NTE_01257	3.545e-66	230.0	arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2582050_1	1459636.NTE_01695	1.939e-155	498.0	COG1163@1|root,arCOG00358@2157|Archaea,41SAD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
SRR25158380_k127_2582050_5	1459636.NTE_00620	7.045e-51	185.0	COG0681@1|root,arCOG01739@2157|Archaea,41SQ2@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158380_k127_2582050_6	748449.Halha_1865	1.592e-18	90.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158380_k127_2585231_3	1459636.NTE_01380	2.062e-32	129.0	arCOG08734@1|root,arCOG08734@2157|Archaea,41SP9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2585231_1	1459636.NTE_01014	2.937e-43	162.0	arCOG10527@1|root,arCOG10527@2157|Archaea,41SPB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2585231_4	1459636.NTE_01015	3.473e-26	117.0	arCOG08733@1|root,arCOG08733@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2585231_0	1459636.NTE_00963	4.244e-82	285.0	arCOG08733@1|root,arCOG08733@2157|Archaea,41SRN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2585231_6	1131266.ARWQ01000010_gene36	3.369e-20	91.0	arCOG11928@1|root,arCOG11928@2157|Archaea,41T8Q@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2585231_2	1459636.NTE_02704	9.129e-42	154.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2594563_0	1459636.NTE_02554	1.759e-14	73.0	COG1143@1|root,arCOG01543@2157|Archaea,41SGW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4
SRR25158380_k127_2596391_15	1459636.NTE_01360	1.059e-43	165.0	COG0640@1|root,arCOG00472@2157|Archaea	2157|Archaea	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_16,AAA_22,DUF2791,HTH_5
SRR25158380_k127_2596391_16	1459636.NTE_01359	3.738e-40	157.0	arCOG03737@1|root,arCOG03737@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2596391_20	1459636.NTE_02641	6.97e-27	113.0	COG0073@1|root,arCOG01136@2157|Archaea,41SSY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRR25158380_k127_2596391_11	1459636.NTE_02643	8.715e-73	255.0	COG2084@1|root,arCOG00247@2157|Archaea,41SI2@651137|Thaumarchaeota	651137|Thaumarchaeota	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158380_k127_2596391_18	1459636.NTE_02651	7.505e-36	138.0	COG2146@1|root,arCOG02852@2157|Archaea,41T71@651137|Thaumarchaeota	651137|Thaumarchaeota	P	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158380_k127_2596391_2	1459636.NTE_02650	3.398e-172	552.0	COG0719@1|root,arCOG01715@2157|Archaea,41S7W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufD	-	-	-	ko:K09014,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158380_k127_2596391_0	1459636.NTE_02649	8.005e-280	863.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158380_k127_2596391_21	1123373.ATXI01000009_gene372	7.689e-13	79.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GH4Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158380_k127_2596391_8	436308.Nmar_0492	6.209e-84	285.0	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
SRR25158380_k127_2596391_7	1459636.NTE_01012	4.939e-99	332.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158380_k127_2596391_1	1459636.NTE_01013	1.218e-172	551.0	COG0001@1|root,arCOG00918@2157|Archaea,41SDE@651137|Thaumarchaeota	651137|Thaumarchaeota	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_2596391_6	1131266.ARWQ01000005_gene821	1.718e-120	396.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158380_k127_2596391_4	1459636.NTE_01382	1.897e-133	437.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158380_k127_2596391_9	1459636.NTE_01383	1.194e-81	276.0	COG1648@1|root,arCOG01044@2157|Archaea,41SN9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
SRR25158380_k127_2596391_5	1459636.NTE_01091	8.4e-130	421.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158380_k127_2596391_17	1459636.NTE_01092	4.668e-36	138.0	COG2139@1|root,arCOG04129@2157|Archaea,41SRF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	-	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
SRR25158380_k127_2596391_19	1459636.NTE_01093	5.057e-35	136.0	COG1460@1|root,arCOG01016@2157|Archaea,41SQ1@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb4	-	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
SRR25158380_k127_2596391_10	1459636.NTE_01094	8.932e-78	265.0	COG1491@1|root,arCOG04130@2157|Archaea,41SGD@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein of unknown function (DUF655)	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
SRR25158380_k127_2596391_13	1459636.NTE_01095	4.664e-56	205.0	COG0030@1|root,arCOG04131@2157|Archaea,41SN0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158380_k127_2596391_14	1459636.NTE_01096	1.464e-45	170.0	COG2890@1|root,arCOG00109@2157|Archaea,41SSD@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158380_k127_2596391_3	1459636.NTE_01097	1.967e-169	537.0	COG0473@1|root,arCOG01163@2157|Archaea,41S5U@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158380_k127_2596391_12	1459636.NTE_01098	1.371e-59	211.0	arCOG08673@1|root,arCOG08673@2157|Archaea	1459636.NTE_01098|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2641574_0	1459636.NTE_03523	2.218e-84	293.0	COG3391@1|root,arCOG08716@1|root,arCOG02562@2157|Archaea,arCOG08716@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PKD
SRR25158380_k127_2669187_1	748449.Halha_2588	6.896e-16	78.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WAR0@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158380_k127_2669187_0	1459636.NTE_01844	5.69e-134	438.0	COG0026@1|root,arCOG01597@2157|Archaea,41SD9@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158380_k127_2673126_0	1459636.NTE_02859	1.456e-113	377.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158380_k127_2673126_1	436308.Nmar_0573	1.726e-54	199.0	COG1528@1|root,arCOG01095@2157|Archaea	2157|Archaea	P	PFAM Ferritin, Dps family protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158380_k127_2673126_2	266117.Rxyl_2895	9.136e-35	140.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158380_k127_2673126_3	350058.Mvan_1399	2.571e-12	70.0	COG1073@1|root,COG1073@2|Bacteria,2I5P1@201174|Actinobacteria,23FC9@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam Dienelactone hydrolase family	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH
SRR25158380_k127_2675964_5	267748.MMOB3950	0.0004732	49.0	COG1554@1|root,COG1554@2|Bacteria,3WT2U@544448|Tenericutes	544448|Tenericutes	G	Glycosyl hydrolase family 65 central catalytic domain	treP	-	2.4.1.64,2.4.1.8	ko:K00691,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R01555,R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158380_k127_2675964_2	933262.AXAM01000126_gene962	4.759e-43	179.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria,2MI6A@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158380_k127_2675964_1	1459636.NTE_01492	1.951e-57	223.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_2675964_3	1459636.NTE_01491	8.285e-20	93.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2675964_0	1459636.NTE_00331	1.598e-112	375.0	COG0517@1|root,arCOG00607@2157|Archaea	2157|Archaea	M	Belongs to the peptidase M50B family	-	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR25158380_k127_2675964_4	211165.AJLN01000085_gene1571	8.685e-06	55.0	COG0515@1|root,COG0515@2|Bacteria,1G0M9@1117|Cyanobacteria,1JJCN@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,PsbP
SRR25158380_k127_2699_33	1459636.NTE_03208	9.419e-20	89.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_2699_13	1459636.NTE_03051	1.413e-125	405.0	COG0090@1|root,arCOG04067@2157|Archaea,41SCT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158380_k127_2699_12	1459636.NTE_01293	1.022e-129	420.0	COG0448@1|root,arCOG00912@2157|Archaea,41SEY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158380_k127_2699_14	1459636.NTE_01292	1.888e-123	413.0	COG0552@1|root,arCOG01227@2157|Archaea,41SCC@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158380_k127_2699_29	1459636.NTE_01291	2.03e-39	151.0	COG1730@1|root,arCOG01341@2157|Archaea,41SSP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	-	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
SRR25158380_k127_2699_9	1459636.NTE_01288	2.77e-157	502.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158380_k127_2699_1	1459636.NTE_01284	0.0	1147.0	COG0495@1|root,arCOG00809@2157|Archaea,41SES@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_2699_0	1459636.NTE_01283	0.0	1217.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158380_k127_2699_25	1459636.NTE_01281	1.254e-47	173.0	COG0526@1|root,arCOG01972@2157|Archaea,41SSR@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158380_k127_2699_40	693661.Arcve_0910	1.262e-05	49.0	arCOG02754@1|root,arCOG02754@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158380_k127_2699_18	521011.Mpal_1345	2.758e-65	235.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_2699_5	1459636.NTE_02817	5.432e-185	589.0	COG0064@1|root,arCOG01718@2157|Archaea,41S9S@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158380_k127_2699_8	436308.Nmar_0869	1.407e-157	510.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158380_k127_2699_38	1459636.NTE_02819	1.697e-10	65.0	COG0721@1|root,arCOG02726@2157|Archaea	2157|Archaea	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158380_k127_2699_7	1459636.NTE_02820	5.513e-181	576.0	COG0017@1|root,arCOG00406@2157|Archaea,41SBT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	-	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_2699_4	1459636.NTE_02809	3.285e-194	614.0	COG1915@1|root,arCOG04422@2157|Archaea,41SBQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR25158380_k127_2699_27	1459636.NTE_02808	1.626e-40	152.0	arCOG08655@1|root,arCOG08655@2157|Archaea,41SR9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2699_26	1459636.NTE_02807	5.148e-42	160.0	COG1896@1|root,arCOG04311@2157|Archaea,41SQE@651137|Thaumarchaeota	651137|Thaumarchaeota	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158380_k127_2699_22	1459636.NTE_02804	1.258e-53	194.0	COG2096@1|root,arCOG00489@2157|Archaea,41T2I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158380_k127_2699_31	1459636.NTE_01238	4.693e-38	143.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01238|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2699_20	1459636.NTE_01333	5.481e-59	215.0	arCOG08708@1|root,arCOG08708@2157|Archaea,41SPK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2699_6	1459636.NTE_01317	5.21e-184	583.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_2699_17	1459636.NTE_03272	6.74e-97	327.0	COG1527@1|root,arCOG02459@2157|Archaea,41T18@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (C/AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SRR25158380_k127_2699_35	1459636.NTE_00455	1.814e-19	92.0	COG2811@1|root,arCOG03363@2157|Archaea,41TA7@651137|Thaumarchaeota	651137|Thaumarchaeota	C	H subunit	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
SRR25158380_k127_2699_11	1459636.NTE_01017	1.835e-134	440.0	COG0585@1|root,arCOG04252@2157|Archaea,41S7C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	tRNA pseudouridine synthase	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
SRR25158380_k127_2699_30	1459636.NTE_01031	1.968e-38	147.0	COG0071@1|root,arCOG01832@2157|Archaea,41T74@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158380_k127_2699_15	1459636.NTE_03054	2.146e-123	402.0	COG2897@1|root,arCOG02019@2157|Archaea,41SBN@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_2699_2	1459636.NTE_03053	6.988e-284	882.0	COG0155@1|root,arCOG02055@2157|Archaea,41S5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Sulfite reductase	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158380_k127_2699_19	1459636.NTE_00448	2.203e-61	216.0	COG1303@1|root,arCOG01857@2157|Archaea,41SIR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	-	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
SRR25158380_k127_2699_16	1459636.NTE_00449	1.278e-122	403.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158380_k127_2699_32	1459636.NTE_00450	3.663e-32	130.0	COG1813@1|root,arCOG01863@2157|Archaea	2157|Archaea	K	transcription factor, homolog of eukaryotic MBF1	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
SRR25158380_k127_2699_23	1459636.NTE_00453	5.866e-50	183.0	COG1370@1|root,arCOG00991@2157|Archaea,41SP1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Patch-forming domain C2 of tRNA-guanine transglycosylase	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
SRR25158380_k127_2699_24	1459636.NTE_00454	6.569e-48	173.0	COG1308@1|root,arCOG04061@2157|Archaea,41SNN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
SRR25158380_k127_2699_21	1459636.NTE_01034	8.794e-54	194.0	COG0494@1|root,arCOG01073@2157|Archaea,41T73@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158380_k127_2699_28	1459636.NTE_01033	3.25e-40	153.0	arCOG03681@1|root,arCOG03681@2157|Archaea,41T6V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2699_3	1459636.NTE_01032	3.341e-205	650.0	COG0661@1|root,arCOG01189@2157|Archaea,41SYQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158380_k127_2699_10	1459636.NTE_00059	8.105e-142	462.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158380_k127_2699_39	1459636.NTE_01491	5.892e-09	62.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2726566_1	436308.Nmar_1268	2.26e-159	507.0	COG0646@1|root,arCOG08715@2157|Archaea,41SWZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
SRR25158380_k127_2726566_0	1459636.NTE_02986	0.0	1154.0	COG0294@1|root,COG1410@1|root,arCOG01978@2157|Archaea,arCOG02029@2157|Archaea,41SXT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
SRR25158380_k127_2726566_3	1459636.NTE_01912	5.551e-32	128.0	COG0159@1|root,arCOG01086@2157|Archaea,41SG0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158380_k127_2749396_1	1408424.JHYI01000018_gene3187	5.991e-18	84.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
SRR25158380_k127_2749396_0	1056495.Calag_1008	9.972e-68	238.0	COG1573@1|root,arCOG00905@2157|Archaea,2XRWR@28889|Crenarchaeota	28889|Crenarchaeota	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158380_k127_2749396_2	1459636.NTE_00230	1.922e-11	65.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158380_k127_2750207_0	1459636.NTE_03510	3.507e-96	325.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158380_k127_2750443_2	489825.LYNGBM3L_06070	1.823e-44	175.0	COG3500@1|root,COG3500@2|Bacteria,1GCWA@1117|Cyanobacteria,1HF6Y@1150|Oscillatoriales	1117|Cyanobacteria	S	Late control gene D protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_3	351160.RCIX1671	1.817e-40	159.0	COG3501@1|root,arCOG10240@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_8	1095767.CAHD01000082_gene2697	7.065e-12	74.0	COG3628@1|root,COG3628@2|Bacteria,2H53I@201174|Actinobacteria	201174|Actinobacteria	S	GPW Gp25 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_1	304371.MCP_0321	2.803e-97	338.0	COG3299@1|root,arCOG10307@2157|Archaea,2Y7DI@28890|Euryarchaeota,2NB3W@224756|Methanomicrobia	224756|Methanomicrobia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158380_k127_2750443_5	351160.RCIX1677	4.448e-34	145.0	arCOG10698@1|root,arCOG10698@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_4	304371.MCP_0323	4.928e-40	157.0	arCOG12571@1|root,arCOG12571@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_9	351160.RCIX1680	1.572e-11	74.0	arCOG12570@1|root,arCOG12570@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_7	351160.RCIX1665	1.937e-18	89.0	arCOG03260@1|root,arCOG03260@2157|Archaea	2157|Archaea	-	-	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CARDB,CarboxypepD_reg,PKD
SRR25158380_k127_2750443_0	351160.RCIX1658	1.518e-139	456.0	COG3497@1|root,arCOG11414@2157|Archaea	2157|Archaea	S	Phage tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158380_k127_2750443_6	1297742.A176_01411	1.781e-22	101.0	arCOG12574@1|root,344J8@2|Bacteria,1NZS6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750443_10	304371.MCP_0313	1.032e-06	53.0	arCOG12573@1|root,arCOG12573@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750627_1	1459636.NTE_00832	5.315e-83	285.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750627_2	1459636.NTE_01064	1.013e-16	83.0	COG0640@1|root,arCOG03067@2157|Archaea,41T7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2750627_0	1459636.NTE_02742	2.401e-220	709.0	COG0672@1|root,arCOG04330@2157|Archaea,41T07@651137|Thaumarchaeota	651137|Thaumarchaeota	P	High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158380_k127_2751039_0	1459636.NTE_01491	1.903e-21	99.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2757238_0	1459636.NTE_03025	0.0	1290.0	COG0060@1|root,arCOG00807@2157|Archaea,41SFF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_2757238_1	573064.Mefer_0896	2.422e-94	316.0	COG0863@1|root,arCOG00115@2157|Archaea,2XWB2@28890|Euryarchaeota,23RT5@183939|Methanococci	183939|Methanococci	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158380_k127_2757238_6	1459636.NTE_01553	6.929e-28	116.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2757238_5	1459636.NTE_00089	2.08e-29	122.0	COG0109@1|root,arCOG03103@2157|Archaea	2157|Archaea	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158380_k127_2757238_7	1229909.NSED_02135	1.283e-12	73.0	arCOG08665@1|root,arCOG08665@2157|Archaea	2157|Archaea	S	Haem utilisation ChuX/HutX	-	-	-	-	-	-	-	-	-	-	-	-	ChuX_HutX
SRR25158380_k127_2757238_8	404380.Gbem_0338	1.201e-10	72.0	COG2133@1|root,COG2133@2|Bacteria,1PUU2@1224|Proteobacteria,433G4@68525|delta/epsilon subdivisions,2WXG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158380_k127_2757238_2	1459636.NTE_00971	9.824e-39	152.0	COG0500@1|root,arCOG01787@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31
SRR25158380_k127_2757238_3	1459636.NTE_03044	4.583e-34	135.0	arCOG08654@1|root,arCOG08654@2157|Archaea,41SRM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2757238_9	1131266.ARWQ01000001_gene1120	1.012e-07	56.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158380_k127_2757238_4	1459636.NTE_01667	1.087e-30	124.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2761267_0	1123073.KB899242_gene946	6.861e-176	585.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria,1X3QM@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA ligase	lig3	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158380_k127_2761267_2	986075.CathTA2_1346	6.58e-49	187.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli	91061|Bacilli	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158380_k127_2761267_3	1459636.NTE_01074	9.348e-12	72.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2761267_5	1027292.HMPREF9372_1903	1.969e-07	61.0	COG3861@1|root,COG3861@2|Bacteria,1V24Q@1239|Firmicutes,4HHDZ@91061|Bacilli,26EWF@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,YflT
SRR25158380_k127_2761267_1	1042377.AFPJ01000044_gene632	1.29e-52	196.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,464C8@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1226 Kef-type K transport systems	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
SRR25158380_k127_2764809_12	1459636.NTE_01424	2.653e-20	89.0	COG1146@1|root,arCOG08753@1|root,arCOG04548@2157|Archaea,arCOG08753@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_2764809_9	1459636.NTE_01423	9.271e-39	149.0	COG1986@1|root,arCOG01223@2157|Archaea,41SKV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158380_k127_2764809_10	1459636.NTE_01422	1.342e-31	128.0	arCOG08641@1|root,arCOG08641@2157|Archaea,41SU7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2764809_14	1459636.NTE_01421	2.943e-14	76.0	arCOG10585@1|root,arCOG10585@2157|Archaea,41SW6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2764809_1	1459636.NTE_01420	6.69e-181	573.0	COG0180@1|root,arCOG01887@2157|Archaea,41SDK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158380_k127_2764809_2	1459636.NTE_01419	3.97e-163	527.0	COG0016@1|root,arCOG00410@2157|Archaea,41S9U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Phenylalanyl-tRNA synthetase alpha subunit	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
SRR25158380_k127_2764809_5	386456.JQKN01000005_gene462	2.125e-80	289.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,23NX2@183925|Methanobacteria	183925|Methanobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,tRNA-synt_2d
SRR25158380_k127_2764809_0	1459636.NTE_02802	4.067e-184	584.0	COG1944@1|root,arCOG02882@2157|Archaea	2157|Archaea	H	methanogenesis marker protein 1	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
SRR25158380_k127_2764809_7	1459636.NTE_02803	1.92e-62	221.0	COG3482@1|root,arCOG05002@2157|Archaea	2157|Archaea	S	PFAM TfuA domain protein, core	-	-	-	-	-	-	-	-	-	-	-	-	TfuA
SRR25158380_k127_2764809_11	1459636.NTE_00739	2.976e-27	117.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T7E@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2764809_6	1459636.NTE_00747	1.509e-69	238.0	COG1632@1|root,arCOG04209@2157|Archaea,41SND@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L15E	-	-	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
SRR25158380_k127_2764809_8	1459636.NTE_02403	4.474e-44	166.0	COG0251@1|root,arCOG01630@2157|Archaea,41T4N@651137|Thaumarchaeota	651137|Thaumarchaeota	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158380_k127_2764809_3	1459636.NTE_00750	3.817e-123	402.0	COG0111@1|root,arCOG01754@2157|Archaea,41S8U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158380_k127_2764809_4	1459636.NTE_01354	4.598e-84	287.0	COG1146@1|root,arCOG04548@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_2767659_0	868131.MSWAN_1817	1.152e-59	209.0	COG5485@1|root,arCOG06513@2157|Archaea,2Y3E5@28890|Euryarchaeota	28890|Euryarchaeota	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158380_k127_2770476_1	1459636.NTE_03094	1.321e-76	272.0	COG0438@1|root,arCOG04796@2157|Archaea,41T9D@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158380_k127_2770476_0	1459636.NTE_01608	5.132e-100	328.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
SRR25158380_k127_2770816_0	247490.KSU1_D0999	5.163e-18	96.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_2772005_2	1122217.KB899616_gene1301	1.78e-25	112.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4H4PA@909932|Negativicutes	909932|Negativicutes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158380_k127_2772005_0	1459636.NTE_03190	1.469e-88	300.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_2772005_1	1131266.ARWQ01000004_gene1476	1.84e-76	266.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_2772005_3	1125863.JAFN01000001_gene3431	6.841e-10	62.0	COG0500@1|root,COG2226@2|Bacteria,1QZV0@1224|Proteobacteria,43CPF@68525|delta/epsilon subdivisions,2WS28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_2772146_2	656024.FsymDg_0437	2.355e-40	153.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2772146_0	1131266.ARWQ01000004_gene1476	9.067e-80	275.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_2772146_1	1255043.TVNIR_3515	5.248e-71	244.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,1SEMI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158380_k127_2776110_3	1459636.NTE_03208	2.452e-12	69.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_2776110_1	1459636.NTE_01970	4.844e-150	483.0	COG0667@1|root,arCOG01623@2157|Archaea,41SA6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_2776110_0	1459636.NTE_02293	1.73e-234	739.0	COG1855@1|root,arCOG04116@2157|Archaea,41SX0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,T2SSE
SRR25158380_k127_2776110_2	1459636.NTE_03210	1.508e-60	215.0	COG0077@1|root,arCOG00255@2157|Archaea,41SA8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158380_k127_2777136_0	1459636.NTE_01403	2.955e-94	317.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
SRR25158380_k127_2777136_1	1229909.NSED_04685	1.143e-31	135.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_2777136_2	1094980.Mpsy_2342	0.0002242	50.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	gvpD	-	-	-	-	-	-	-	-	-	-	-	GvpD
SRR25158380_k127_2779591_1	1459636.NTE_03322	2.318e-45	169.0	COG0499@1|root,arCOG04137@2157|Archaea,41S9I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158380_k127_2779591_2	1459636.NTE_03320	8.855e-45	164.0	COG2146@1|root,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	1.7.1.15	ko:K00363,ko:K15762	ko00623,ko00910,ko00920,ko01100,ko01120,ko01220,map00623,map00910,map00920,map01100,map01120,map01220	M00530,M00538	R00787,R02550,R03562,R05666,R09513	RC00176,RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
SRR25158380_k127_2779591_0	1459636.NTE_03319	1.035e-162	524.0	COG0215@1|root,arCOG00486@2157|Archaea,41SEW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PFAM tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158380_k127_2779837_0	1459636.NTE_02508	1.714e-76	263.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
SRR25158380_k127_2779837_3	436308.Nmar_0879	8.118e-22	97.0	arCOG08746@1|root,arCOG08746@2157|Archaea,41SWA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
SRR25158380_k127_2779837_2	1459636.NTE_02510	1.389e-48	181.0	arCOG02103@1|root,arCOG02103@2157|Archaea,41T51@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF4443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4443
SRR25158380_k127_2779837_1	1459636.NTE_01334	2.062e-64	226.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_2786279_7	1459636.NTE_03034	6.718e-41	154.0	COG2125@1|root,arCOG01946@2157|Archaea,41SPC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	-	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
SRR25158380_k127_2786279_2	1459636.NTE_03035	4.322e-202	636.0	COG3276@1|root,arCOG01563@2157|Archaea,41S80@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Initiation factor	-	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,eIF2_C
SRR25158380_k127_2786279_13	1459636.NTE_03033	3.363e-16	80.0	arCOG08820@1|root,arCOG08820@2157|Archaea,41SWF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2786279_3	1459636.NTE_01080	1.697e-199	625.0	COG1697@1|root,arCOG04143@2157|Archaea,41SQF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
SRR25158380_k127_2786279_1	1459636.NTE_01081	7.141e-257	807.0	COG1389@1|root,arCOG01165@2157|Archaea,41SJ2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
SRR25158380_k127_2786279_0	1459636.NTE_03038	2.017e-317	996.0	COG0652@1|root,COG1287@1|root,arCOG02044@2157|Archaea,arCOG04767@2157|Archaea,41SBI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Oligosaccharyl transferase STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
SRR25158380_k127_2786279_5	1459636.NTE_03041	3.292e-128	417.0	COG1899@1|root,arCOG04142@2157|Archaea,41SDB@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158380_k127_2786279_4	1459636.NTE_03043	2e-160	514.0	COG1899@1|root,arCOG04142@2157|Archaea,41SWS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158380_k127_2786279_8	1131266.ARWQ01000005_gene845	7.126e-40	154.0	COG1547@1|root,arCOG03705@2157|Archaea,41SQ0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158380_k127_2786279_15	1459636.NTE_00621	1.081e-12	72.0	arCOG08691@1|root,arCOG08691@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2786279_11	436308.Nmar_1432	1.126e-18	87.0	COG2036@1|root,arCOG02144@2157|Archaea,41T91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	transcription factor (CBF NF-Y)	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
SRR25158380_k127_2786279_9	1459636.NTE_01307	1.093e-34	135.0	arCOG10523@1|root,arCOG10523@2157|Archaea,41SSZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2786279_6	1459636.NTE_01614	3.109e-90	302.0	COG1241@1|root,arCOG00439@2157|Archaea	2157|Archaea	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_OB
SRR25158380_k127_2786279_12	1459636.NTE_03059	2.885e-17	81.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2786615_1	1459636.NTE_00738	5.036e-05	45.0	arCOG10856@1|root,arCOG10856@2157|Archaea	1459636.NTE_00738|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2786615_0	1459636.NTE_03552	6.072e-115	378.0	COG0123@1|root,arCOG00324@2157|Archaea	2157|Archaea	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158380_k127_2788067_1	1459636.NTE_00795	1.761e-81	278.0	COG1055@1|root,arCOG00238@2157|Archaea,41SXH@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158380_k127_2788067_0	1459636.NTE_00389	7.976e-136	443.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158380_k127_2788067_4	1459636.NTE_00200	5.532e-11	68.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2788067_2	1459636.NTE_02435	1.785e-17	85.0	arCOG03008@1|root,arCOG03008@2157|Archaea,41STF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158380_k127_2796062_0	1459636.NTE_03030	3.067e-47	175.0	COG2453@1|root,arCOG03413@2157|Archaea,41SK5@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Dual specificity phosphatase, catalytic domain	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
SRR25158380_k127_2797190_11	1459636.NTE_00641	2.701e-27	113.0	arCOG08704@1|root,arCOG08704@2157|Archaea,41STG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2797190_7	1459636.NTE_00640	8.542e-48	174.0	arCOG08703@1|root,arCOG08703@2157|Archaea,41SS0@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2797190_13	1459636.NTE_00639	1.554e-20	95.0	arCOG08702@1|root,arCOG08702@2157|Archaea,41ST2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2797190_9	1459636.NTE_00652	1.974e-33	134.0	COG0494@1|root,arCOG01078@2157|Archaea,41SPS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158380_k127_2797190_4	1459636.NTE_00400	2.303e-111	365.0	COG0020@1|root,arCOG01532@2157|Archaea,41S8J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	-	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
SRR25158380_k127_2797190_2	1459636.NTE_00649	5.185e-148	477.0	COG2237@1|root,arCOG04151@2157|Archaea,41SA3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
SRR25158380_k127_2797190_0	1459636.NTE_02046	4.332e-223	700.0	COG0381@1|root,arCOG01392@2157|Archaea	2157|Archaea	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158380_k127_2797190_12	1459636.NTE_02047	1.521e-20	96.0	arCOG08683@1|root,arCOG08683@2157|Archaea,41SUM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2797190_3	1459636.NTE_02048	6.089e-141	455.0	COG1085@1|root,arCOG00422@2157|Archaea,41S6T@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158380_k127_2797190_8	1459636.NTE_03311	5.217e-35	134.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2797190_1	1459636.NTE_01905	1.611e-152	488.0	COG0057@1|root,arCOG00493@2157|Archaea,41SDF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158380_k127_2797190_6	1459636.NTE_01906	8.089e-84	281.0	COG0512@1|root,arCOG00086@2157|Archaea,41SGV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158380_k127_2797190_5	1459636.NTE_01907	2.536e-89	306.0	COG0547@1|root,arCOG02012@2157|Archaea,41SGG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158380_k127_2797190_10	1459636.NTE_00784	1.303e-27	115.0	COG2004@1|root,arCOG04182@2157|Archaea,41SWI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS24 family	-	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
SRR25158380_k127_2797190_14	1459636.NTE_00783	7.511e-20	89.0	COG1998@1|root,arCOG04183@2157|Archaea,41SWB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
SRR25158380_k127_2805190_4	1459636.NTE_01467	2.136e-140	467.0	COG3356@1|root,arCOG04351@2157|Archaea,41S7S@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
SRR25158380_k127_2805190_15	1459636.NTE_01468	6.889e-21	93.0	COG4023@1|root,arCOG02957@2157|Archaea,41SUS@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Sec61beta family	-	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
SRR25158380_k127_2805190_13	1459636.NTE_01470	1.231e-51	184.0	COG0023@1|root,arCOG04223@2157|Archaea,41SNU@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR25158380_k127_2805190_3	1459636.NTE_01473	2.919e-185	580.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158380_k127_2805190_0	1459636.NTE_00773	1.066e-267	846.0	COG3889@1|root,arCOG10597@1|root,arCOG01672@2157|Archaea,arCOG10597@2157|Archaea,41SA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158380_k127_2805190_14	1459636.NTE_00016	2.613e-49	185.0	COG1058@1|root,arCOG00215@2157|Archaea	2157|Archaea	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	cinA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158380_k127_2805190_11	1459636.NTE_02599	7.736e-90	306.0	COG1829@1|root,arCOG04263@2157|Archaea,41T1V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	kinase, sugar kinase superfamily	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
SRR25158380_k127_2805190_12	1459636.NTE_02600	2.952e-82	280.0	COG1701@1|root,arCOG04262@2157|Archaea,41SXP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pfam:DUF137	-	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
SRR25158380_k127_2805190_8	1459636.NTE_02601	7.23e-105	348.0	COG0413@1|root,arCOG00584@2157|Archaea,41SZX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158380_k127_2805190_6	1459636.NTE_02602	1.314e-124	412.0	COG0452@1|root,arCOG01704@2157|Archaea,41SYG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158380_k127_2805190_7	1459636.NTE_02604	7.448e-111	369.0	COG0006@1|root,arCOG01000@2157|Archaea,41T14@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158380_k127_2805190_2	1459636.NTE_02607	1.683e-197	620.0	COG0075@1|root,arCOG00082@2157|Archaea,41SZZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158380_k127_2805190_10	1459636.NTE_02621	4.041e-93	313.0	COG1047@1|root,arCOG00980@2157|Archaea,41T0T@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158380_k127_2805190_5	1459636.NTE_01413	5.775e-129	421.0	COG0371@1|root,arCOG00982@2157|Archaea,41T0B@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
SRR25158380_k127_2805190_16	1459636.NTE_01414	7.872e-19	89.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158380_k127_2805190_1	1459636.NTE_01415	8.667e-199	638.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	651137|Thaumarchaeota	S	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
SRR25158380_k127_2805190_9	1459636.NTE_01308	1.945e-93	314.0	COG0727@1|root,arCOG02579@2157|Archaea,41SH8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158380_k127_2805190_17	1459636.NTE_01469	2.874e-09	64.0	COG1645@1|root,arCOG00578@2157|Archaea,41SVN@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	-	-	-	ko:K07143	-	-	-	-	ko00000	-	-	-	Auto_anti-p27
SRR25158380_k127_2807211_1	1223523.H340_21271	5.207e-10	63.0	COG1359@1|root,COG1359@2|Bacteria,2IR79@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158380_k127_2807211_0	1459636.NTE_02412	2.978e-16	81.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_2807211_2	1459636.NTE_00004	2.219e-05	50.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158380_k127_2807345_0	1459636.NTE_00950	3.962e-182	575.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_282715_0	1459636.NTE_00373	5.538e-102	346.0	COG2124@1|root,arCOG02814@2157|Archaea	2157|Archaea	C	cytochrome P450	cyp119	-	1.11.1.7,1.14.14.1	ko:K00493,ko:K21201	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158380_k127_282715_1	1382359.JIAL01000001_gene2832	6.097e-43	159.0	COG1064@1|root,COG1064@2|Bacteria,3Y33B@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_2827884_0	1459636.NTE_03308	5.776e-57	206.0	COG1515@1|root,arCOG00929@2157|Archaea	2157|Archaea	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158380_k127_2827884_1	868131.MSWAN_1817	2.274e-16	79.0	COG5485@1|root,arCOG06513@2157|Archaea,2Y3E5@28890|Euryarchaeota	28890|Euryarchaeota	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158380_k127_2833177_1	1123296.JQKE01000130_gene1250	2.504e-21	102.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KQRJ@206351|Neisseriales	206351|Neisseriales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158380_k127_2833177_0	686340.Metal_1092	3.598e-76	270.0	COG2132@1|root,COG2132@2|Bacteria,1QR33@1224|Proteobacteria,1SMFR@1236|Gammaproteobacteria,1XG58@135618|Methylococcales	135618|Methylococcales	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_2833391_0	1459636.NTE_00560	1.919e-12	70.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_284163_0	1459636.NTE_02717	1.105e-49	188.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158380_k127_284163_2	1227454.C446_12374	2.821e-16	80.0	COG2141@1|root,arCOG02410@2157|Archaea,2XSUT@28890|Euryarchaeota,23UB6@183963|Halobacteria	183963|Halobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_284163_1	1459636.NTE_02636	1.271e-20	97.0	COG1525@1|root,arCOG03192@2157|Archaea,41T4A@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158380_k127_2842784_0	1131266.ARWQ01000006_gene279	2.349e-53	192.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T43@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_2846910_17	1459636.NTE_00526	2.613e-10	61.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	2157|Archaea	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
SRR25158380_k127_2846910_0	1459636.NTE_02319	0.0	1088.0	COG1964@1|root,arCOG00933@2157|Archaea,41SAY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_2846910_2	1459636.NTE_02211	8.122e-134	431.0	COG1250@1|root,arCOG00249@2157|Archaea	2157|Archaea	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.116,4.2.1.17	ko:K01715,ko:K15019	ko00650,ko00720,ko01120,ko01200,map00650,map00720,map01120,map01200	M00375	R03026,R03045	RC00831,RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158380_k127_2846910_7	1459636.NTE_02212	1.355e-93	316.0	COG0083@1|root,arCOG01027@2157|Archaea,41S89@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_2846910_6	1459636.NTE_02213	1.169e-93	313.0	COG1100@1|root,arCOG01225@2157|Archaea,41T0A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR25158380_k127_2846910_5	1459636.NTE_02215	7.884e-103	344.0	COG0392@1|root,arCOG00899@2157|Archaea,41SFV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158380_k127_2846910_13	1459636.NTE_02216	4.411e-38	147.0	arCOG10514@1|root,arCOG10514@2157|Archaea,41STR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2846910_11	985053.VMUT_0848	1.527e-41	160.0	COG0328@1|root,arCOG02942@2157|Archaea,2XR72@28889|Crenarchaeota	28889|Crenarchaeota	L	Reverse transcriptase-like	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158380_k127_2846910_9	1459636.NTE_01560	2.937e-56	201.0	COG1573@1|root,arCOG00905@2157|Archaea,41SJ1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158380_k127_2846910_14	582899.Hden_0696	2.115e-19	96.0	COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,2UAPN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glycine cleavage H-protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158380_k127_2846910_3	1459636.NTE_01352	1.793e-115	378.0	COG2897@1|root,arCOG02019@2157|Archaea,41SZQ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158380_k127_2846910_12	1459636.NTE_01720	6.124e-41	157.0	COG4063@1|root,arCOG03220@2157|Archaea,41T46@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrahydromethanopterin S-methyltransferase, subunit A	-	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
SRR25158380_k127_2846910_8	1459636.NTE_01736	9.869e-71	243.0	COG2109@1|root,arCOG04678@2157|Archaea,41SFP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ATP corrinoid adenosyltransferase	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158380_k127_2846910_4	1459636.NTE_01737	8.435e-105	346.0	COG1093@1|root,arCOG04107@2157|Archaea,41SHY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor 2, alpha subunit	-	-	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
SRR25158380_k127_2846910_16	1459636.NTE_01738	2.55e-13	71.0	COG2260@1|root,arCOG00906@2157|Archaea,41SUI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
SRR25158380_k127_2846910_18	1144275.COCOR_04558	5.169e-08	63.0	2C7PU@1|root,33JNE@2|Bacteria	2|Bacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
SRR25158380_k127_2846910_1	1459636.NTE_01739	3.641e-157	501.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	2157|Archaea	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8,Pyr_redox_2
SRR25158380_k127_2846910_15	1121889.AUDM01000006_gene1605	1.117e-14	81.0	COG1215@1|root,COG1215@2|Bacteria,4NFXI@976|Bacteroidetes,1HXPW@117743|Flavobacteriia,2NSI4@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_2862453_0	1459636.NTE_02584	4.379e-64	227.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_2921094_2	1265505.ATUG01000001_gene3097	4.269e-05	48.0	COG0745@1|root,COG2204@1|root,COG3852@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,1NWAF@1224|Proteobacteria,430TW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-like ATPases	ompR_2	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07677,ko:K07679,ko:K13924,ko:K20974	ko02020,ko02025,ko02026,ko02030,ko05133,map02020,map02025,map02026,map02030,map05133	M00474,M00477,M00506,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg,Trans_reg_C
SRR25158380_k127_2921094_1	1243664.CAVL020000057_gene3162	3.103e-13	76.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,1ZCRU@1386|Bacillus	91061|Bacilli	T	Transcriptional regulator	vanR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_2945902_14	1131266.ARWQ01000002_gene632	4.456e-154	491.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	2157|Archaea	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384,ko:K03387	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158380_k127_2945902_37	521011.Mpal_1474	1.743e-61	227.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_2945902_45	1459636.NTE_00421	7.655e-40	149.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
SRR25158380_k127_2945902_43	1459636.NTE_01719	3.591e-44	164.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T4V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2945902_46	1459636.NTE_01042	2.999e-37	147.0	arCOG08812@1|root,arCOG08812@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2945902_28	436308.Nmar_0044	2.827e-83	283.0	COG0300@1|root,arCOG01263@2157|Archaea,41SXQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158380_k127_2945902_1	1459636.NTE_02924	1.471e-294	927.0	COG1205@1|root,arCOG00555@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158380_k127_2945902_48	1131266.ARWQ01000014_gene96	9.029e-31	126.0	COG0346@1|root,arCOG02708@2157|Archaea,41T5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158380_k127_2945902_17	1459636.NTE_01652	1.931e-130	435.0	COG4257@1|root,arCOG03564@2157|Archaea,41SM7@651137|Thaumarchaeota	651137|Thaumarchaeota	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SRR25158380_k127_2945902_39	1459636.NTE_02430	1.009e-52	200.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_2945902_55	1459636.NTE_02806	1.664e-10	63.0	arCOG10404@1|root,arCOG10404@2157|Archaea	1459636.NTE_02806|-	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2945902_4	1459636.NTE_03220	3.957e-242	756.0	COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158380_k127_2945902_44	1459636.NTE_03219	2.706e-42	163.0	arCOG05463@1|root,arCOG05463@2157|Archaea,41SR3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2945902_26	1459636.NTE_03217	1.835e-88	298.0	COG1634@1|root,arCOG04303@2157|Archaea,41SKX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
SRR25158380_k127_2945902_16	1459636.NTE_02684	3.756e-132	431.0	COG1679@1|root,arCOG04278@2157|Archaea,41SBC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
SRR25158380_k127_2945902_47	1459636.NTE_02685	4.358e-33	132.0	COG1786@1|root,arCOG04279@2157|Archaea,41SPA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
SRR25158380_k127_2945902_52	1459636.NTE_02161	3.361e-17	83.0	COG1958@1|root,arCOG00998@2157|Archaea,41SU9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
SRR25158380_k127_2945902_5	1459636.NTE_03212	6.172e-240	748.0	COG0516@1|root,arCOG00612@2157|Archaea,41S7R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158380_k127_2945902_27	1459636.NTE_03213	1.151e-85	291.0	COG0294@1|root,arCOG02817@2157|Archaea,41SGK@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158380_k127_2945902_15	1459636.NTE_02703	5.29e-148	474.0	COG1736@1|root,arCOG04112@2157|Archaea,41SE0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Diphthamide biosynthesis	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
SRR25158380_k127_2945902_19	1459636.NTE_02687	6.982e-123	400.0	COG0037@1|root,arCOG00042@2157|Archaea,41S84@651137|Thaumarchaeota	651137|Thaumarchaeota	D	PP-loop family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
SRR25158380_k127_2945902_51	1501391.LG35_00020	7.164e-18	89.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,2FMP2@200643|Bacteroidia,22VD5@171550|Rikenellaceae	976|Bacteroidetes	K	Transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158380_k127_2945902_49	1459636.NTE_02686	1.181e-25	107.0	arCOG08817@1|root,arCOG08817@2157|Archaea,41SV5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2945902_31	1459636.NTE_01636	1.405e-75	259.0	COG0615@1|root,arCOG03924@1|root,arCOG01222@2157|Archaea,arCOG03924@2157|Archaea,41SPR@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Cytidylyltransferase-like	-	-	2.7.7.2,2.7.7.39	ko:K00980,ko:K14656	ko00564,ko00740,ko01100,ko01110,map00564,map00740,map01100,map01110	-	R00161,R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158380_k127_2945902_30	1459636.NTE_01635	6.469e-81	275.0	COG1339@1|root,arCOG01904@2157|Archaea,41SG9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Domain of unknown function DUF120	-	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase
SRR25158380_k127_2945902_12	1459636.NTE_01634	1.305e-176	563.0	COG0358@1|root,arCOG04281@2157|Archaea,41S75@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
SRR25158380_k127_2945902_54	1459636.NTE_00825	1.461e-10	66.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158380_k127_2945902_8	1459636.NTE_02631	1.704e-213	668.0	COG0334@1|root,arCOG01352@2157|Archaea,41S7T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_2945902_38	1459636.NTE_02622	1.867e-57	202.0	COG0316@1|root,arCOG04560@2157|Archaea,41SKH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158380_k127_2945902_0	1459636.NTE_01631	0.0	1077.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S7I@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18594	ko00720,ko01120,map00720,map01120	-	R03157	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158380_k127_2945902_40	1459636.NTE_02633	2.637e-52	191.0	COG2178@1|root,arCOG04318@2157|Archaea,41SKR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
SRR25158380_k127_2945902_42	1459636.NTE_02634	1.05e-46	173.0	COG1591@1|root,arCOG00919@2157|Archaea,41SQP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
SRR25158380_k127_2945902_33	1459636.NTE_01555	4.626e-68	239.0	COG0063@1|root,arCOG00018@2157|Archaea,41SHM@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
SRR25158380_k127_2945902_29	1459636.NTE_01556	2.996e-83	280.0	arCOG00517@1|root,arCOG00517@2157|Archaea,41SHJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_2945902_20	1459636.NTE_01557	2.532e-111	371.0	COG2038@1|root,arCOG04272@2157|Archaea,41SD3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the UPF0284 family	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
SRR25158380_k127_2945902_6	1459636.NTE_02223	3.789e-228	720.0	COG0449@1|root,arCOG00057@2157|Archaea,41SFG@651137|Thaumarchaeota	651137|Thaumarchaeota	M	TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158380_k127_2945902_21	1459636.NTE_02224	8.001e-111	367.0	COG0640@1|root,arCOG03420@1|root,arCOG01687@2157|Archaea,arCOG03420@2157|Archaea	2157|Archaea	K	PFAM S-layer	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,S_layer_C
SRR25158380_k127_2945902_36	1459636.NTE_02225	1.353e-61	216.0	COG0522@1|root,arCOG04239@2157|Archaea,41SN3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
SRR25158380_k127_2945902_34	1459636.NTE_02226	3.531e-65	226.0	COG0099@1|root,arCOG01722@2157|Archaea,41SIW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158380_k127_2945902_10	1459636.NTE_02229	1.824e-206	655.0	COG1239@1|root,arCOG00438@2157|Archaea	2157|Archaea	H	magnesium chelatase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5
SRR25158380_k127_2945902_11	1459636.NTE_02230	1.831e-190	605.0	COG2304@1|root,arCOG02900@2157|Archaea	2157|Archaea	O	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158380_k127_2945902_18	1459636.NTE_00598	1.626e-124	403.0	COG0714@1|root,arCOG00441@2157|Archaea,41SDZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
SRR25158380_k127_2945902_7	1459636.NTE_00599	7.934e-223	702.0	COG2304@1|root,arCOG02900@2157|Archaea,41SDY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2945902_23	1459636.NTE_00600	1.574e-102	337.0	COG0176@1|root,arCOG05061@2157|Archaea,41S99@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158380_k127_2945902_24	999411.HMPREF1092_00159	9.452e-98	329.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,36E9P@31979|Clostridiaceae	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158380_k127_2945902_2	1459636.NTE_00602	8.347e-263	818.0	COG0036@1|root,COG3959@1|root,arCOG01053@2157|Archaea,arCOG05046@2157|Archaea,41SBE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim,Transketolase_N
SRR25158380_k127_2945902_13	1459636.NTE_00604	3.438e-155	503.0	COG0260@1|root,arCOG04322@2157|Archaea,41SYD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158380_k127_2945902_3	1131266.ARWQ01000015_gene746	4.884e-247	778.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
SRR25158380_k127_2945902_25	1459636.NTE_00608	2.754e-94	316.0	COG2520@1|root,arCOG00033@2157|Archaea,41S7P@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Met-10+ like-protein	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
SRR25158380_k127_2945902_32	1459636.NTE_00612	4.407e-75	254.0	COG0456@1|root,arCOG00833@2157|Archaea,41SIY@651137|Thaumarchaeota	651137|Thaumarchaeota	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158380_k127_2945902_41	1459636.NTE_00614	1.161e-51	197.0	COG3875@1|root,arCOG02046@2157|Archaea,41SK4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2945902_22	1459636.NTE_00618	1.133e-105	344.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
SRR25158380_k127_2945902_9	1459636.NTE_00759	1.799e-209	661.0	COG1027@1|root,COG1670@1|root,arCOG00842@2157|Archaea,arCOG01750@2157|Archaea,41S9C@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158380_k127_2945902_57	1459636.NTE_03103	3.431e-07	52.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158380_k127_2954614_2	953739.SVEN_6790	3.769e-06	57.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158380_k127_2954614_0	67281.JNZZ01000019_gene176	2.008e-22	99.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria,41AVX@629295|Streptomyces griseus group	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2954614_1	266117.Rxyl_1184	5.82e-11	64.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158380_k127_2955681_1	644281.MFS40622_1531	4.243e-22	101.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2955681_0	1229909.NSED_09465	3.408e-31	136.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2963306_21	1459636.NTE_03074	2.803e-12	71.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2963306_20	1459636.NTE_00083	3.653e-29	122.0	arCOG04038@1|root,arCOG04038@2157|Archaea,41SQU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2963306_22	237368.SCABRO_01742	1.995e-11	68.0	COG4095@1|root,COG4095@2|Bacteria,2J3PM@203682|Planctomycetes	203682|Planctomycetes	S	PQ loop repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2963306_2	1459636.NTE_03147	3.065e-160	512.0	COG0484@1|root,arCOG06880@1|root,arCOG02846@2157|Archaea,arCOG06880@2157|Archaea,41SCZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ central domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158380_k127_2963306_0	1459636.NTE_03148	1.644e-313	969.0	COG0443@1|root,arCOG03060@2157|Archaea,41SCM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158380_k127_2963306_17	1459636.NTE_03149	2.362e-47	177.0	COG0576@1|root,arCOG04772@2157|Archaea,41SSU@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158380_k127_2963306_18	1459636.NTE_03150	2.829e-45	168.0	COG0526@1|root,arCOG01972@2157|Archaea	2157|Archaea	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158380_k127_2963306_14	1459636.NTE_03154	3.256e-73	248.0	COG1601@1|root,arCOG01640@2157|Archaea,41STZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor	-	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	eIF-5_eIF-2B
SRR25158380_k127_2963306_9	1459636.NTE_03164	1.518e-98	323.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_2963306_1	1459636.NTE_03162	1.723e-182	579.0	COG0004@1|root,arCOG04397@2157|Archaea,41SZ0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158380_k127_2963306_4	1459636.NTE_03161	1.167e-146	473.0	COG0399@1|root,arCOG00118@2157|Archaea,41S96@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158380_k127_2963306_6	1459636.NTE_03188	3.734e-141	457.0	COG2133@1|root,arCOG02796@2157|Archaea,41S7F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158380_k127_2963306_5	1459636.NTE_03194	3.02e-145	472.0	COG1257@1|root,arCOG04260@2157|Archaea,41SAU@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
SRR25158380_k127_2963306_3	1459636.NTE_03195	2.415e-156	498.0	COG0040@1|root,arCOG02208@2157|Archaea,41SCJ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ATP phosphoribosyltransferase	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158380_k127_2963306_8	1229909.NSED_00715	6.127e-118	393.0	COG0141@1|root,arCOG04352@2157|Archaea,41S6J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158380_k127_2963306_10	1459636.NTE_03197	2.785e-92	314.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158380_k127_2963306_13	1459636.NTE_03198	7.774e-74	260.0	COG0546@1|root,arCOG04692@2157|Archaea,41SJ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR25158380_k127_2963306_12	1459636.NTE_03201	3.904e-75	257.0	COG0131@1|root,arCOG04398@2157|Archaea,41SGY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158380_k127_2963306_11	1459636.NTE_03202	7.191e-81	274.0	COG0118@1|root,arCOG00089@2157|Archaea,41SY2@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158380_k127_2963306_15	1459636.NTE_03203	1.072e-72	252.0	COG0106@1|root,arCOG00618@2157|Archaea,41SIG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158380_k127_2963306_7	1459636.NTE_03204	5.124e-127	411.0	COG0107@1|root,arCOG00617@2157|Archaea,41S9A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158380_k127_2963306_19	1459636.NTE_00723	2.047e-44	163.0	COG0361@1|root,arCOG01179@2157|Archaea,41SRK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	-	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
SRR25158380_k127_2963306_24	1131266.ARWQ01000005_gene804	0.0004035	45.0	COG0580@1|root,arCOG04431@2157|Archaea,41SJI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158380_k127_2963306_25	1459636.NTE_00200	0.0004156	47.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2963306_23	1459636.NTE_00200	5.194e-08	60.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2966405_3	1267533.KB906736_gene1024	1.573e-07	57.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2966405_0	269797.Mbar_A0813	1.201e-150	487.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVFS@28890|Euryarchaeota,2NAF6@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158380_k127_2966405_2	1459636.NTE_00427	1.121e-17	91.0	arCOG06357@1|root,arCOG06357@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2966405_1	1459636.NTE_01334	1.07e-80	280.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_2977512_34	171693.BN988_01686	9.094e-45	171.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,4HB3X@91061|Bacilli,23MUV@182709|Oceanobacillus	91061|Bacilli	P	Sodium/calcium exchanger protein	cax	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158380_k127_2977512_15	1459636.NTE_02504	5.086e-97	331.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_2977512_18	1304885.AUEY01000014_gene3322	1.651e-87	306.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
SRR25158380_k127_2977512_27	1459636.NTE_00594	2.163e-58	207.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2977512_33	1459636.NTE_00594	6.5e-45	169.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2977512_30	1459636.NTE_03298	1.526e-50	186.0	arCOG08024@1|root,arCOG08024@2157|Archaea,41SRU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158380_k127_2977512_40	1459636.NTE_03299	6.856e-30	123.0	arCOG08025@1|root,arCOG08025@2157|Archaea,41STV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158380_k127_2977512_38	1459636.NTE_02738	6.397e-34	132.0	COG1384@1|root,arCOG00485@2157|Archaea	1459636.NTE_02738|-	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2977512_20	1459636.NTE_02764	4.077e-82	276.0	COG0302@1|root,arCOG04542@2157|Archaea,41SGC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158380_k127_2977512_14	1459636.NTE_02763	1.989e-97	323.0	COG0602@1|root,arCOG02173@2157|Archaea,41SGM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_2977512_19	1229909.NSED_09825	2.379e-86	293.0	COG0603@1|root,arCOG00039@2157|Archaea,41SGR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Queuosine biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR25158380_k127_2977512_9	1459636.NTE_02737	1.454e-119	394.0	COG0470@1|root,arCOG00469@2157|Archaea,41SFJ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Replication factor C	-	-	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	DNA_pol3_delta2,Rep_fac_C,RuvB_N
SRR25158380_k127_2977512_29	1459636.NTE_02736	2.498e-51	188.0	arCOG00552@1|root,arCOG00552@2157|Archaea,41SRW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	GINS complex protein	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	Sld5
SRR25158380_k127_2977512_0	1459636.NTE_02735	0.0	1060.0	COG1241@1|root,arCOG00439@2157|Archaea,41SA7@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
SRR25158380_k127_2977512_4	1459636.NTE_01247	1.092e-153	491.0	COG0667@1|root,arCOG01617@2157|Archaea,41S90@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_2977512_31	1459636.NTE_01246	3.961e-46	175.0	COG1715@1|root,arCOG09740@2157|Archaea,41T5F@651137|Thaumarchaeota	651137|Thaumarchaeota	V	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158380_k127_2977512_13	1459636.NTE_01245	9.31e-106	349.0	COG3253@1|root,arCOG03031@2157|Archaea,41SGX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158380_k127_2977512_6	1459636.NTE_01244	2.781e-131	422.0	COG0396@1|root,arCOG04236@2157|Archaea,41SE1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158380_k127_2977512_43	1459636.NTE_01241	2.154e-22	102.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_01241|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2977512_46	1459636.NTE_01240	2.94e-08	56.0	arCOG08678@1|root,arCOG08678@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2977512_17	1459636.NTE_01338	4.181e-93	310.0	COG0202@1|root,arCOG04241@2157|Archaea,41SK0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
SRR25158380_k127_2977512_36	1459636.NTE_01337	9.185e-39	148.0	COG1727@1|root,arCOG00780@2157|Archaea,41SRE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18
SRR25158380_k127_2977512_26	1459636.NTE_01336	3.037e-61	214.0	COG0102@1|root,arCOG04242@2157|Archaea,41SP4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158380_k127_2977512_25	1459636.NTE_01335	4.119e-68	235.0	COG0088@1|root,arCOG04243@2157|Archaea,41SKT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS9 family	-	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158380_k127_2977512_16	1459636.NTE_01339	2.978e-96	319.0	COG1500@1|root,arCOG04187@2157|Archaea,41SC7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	-	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
SRR25158380_k127_2977512_12	1459636.NTE_01342	7.534e-108	355.0	COG1097@1|root,arCOG00678@2157|Archaea,41SHV@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	-	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	KH_1
SRR25158380_k127_2977512_8	1459636.NTE_01343	5.012e-125	404.0	COG0689@1|root,arCOG01575@2157|Archaea,41S81@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	-	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
SRR25158380_k127_2977512_11	1459636.NTE_01344	7.805e-112	366.0	COG2123@1|root,arCOG01574@2157|Archaea,41SFZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	-	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
SRR25158380_k127_2977512_39	1459636.NTE_01345	6.713e-30	120.0	COG1997@1|root,arCOG04208@2157|Archaea,41SUE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal L37ae protein family	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
SRR25158380_k127_2977512_35	1459636.NTE_01347	2.971e-39	149.0	COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
SRR25158380_k127_2977512_24	1459636.NTE_01348	7.947e-69	241.0	COG1948@1|root,arCOG04206@2157|Archaea,41SIH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ERCC4 domain	-	-	-	ko:K10848	ko03420,ko03460,map03420,map03460	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	ERCC4,HHH_5
SRR25158380_k127_2977512_22	1459636.NTE_02410	3.33e-70	244.0	COG3467@1|root,arCOG00520@2157|Archaea,41SJ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158380_k127_2977512_3	1459636.NTE_01248	1.583e-154	493.0	COG1522@1|root,arCOG01628@2157|Archaea,41SA2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2977512_23	1459636.NTE_01384	4.625e-70	243.0	COG0250@1|root,arCOG01920@2157|Archaea,41SM6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
SRR25158380_k127_2977512_21	1459636.NTE_01197	4.6e-73	249.0	COG0080@1|root,arCOG04372@2157|Archaea,41SJW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158380_k127_2977512_1	1459636.NTE_01192	6.346e-285	882.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
SRR25158380_k127_2977512_47	591019.Shell_1181	3.529e-05	49.0	COG0550@1|root,arCOG01527@2157|Archaea,2XQ00@28889|Crenarchaeota	28889|Crenarchaeota	L	DNA topoisomerase, type IA, central domain protein	topA	-	5.99.1.2	ko:K03168,ko:K03169	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
SRR25158380_k127_2977512_28	1459636.NTE_02718	5.504e-52	189.0	COG1056@1|root,arCOG00972@2157|Archaea,41T7B@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158380_k127_2977512_5	1459636.NTE_02721	3.806e-142	464.0	COG0252@1|root,arCOG01924@2157|Archaea,41SD7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158380_k127_2977512_2	1459636.NTE_02722	5.086e-246	775.0	COG2511@1|root,arCOG01719@2157|Archaea,41S8Q@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	-	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
SRR25158380_k127_2977512_45	1123058.KB894281_gene1833	1.202e-09	66.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158380_k127_2977512_10	1459636.NTE_02716	1.347e-113	376.0	COG0430@1|root,arCOG04125@2157|Archaea,41T1K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC
SRR25158380_k127_2977512_37	1459636.NTE_01187	1.459e-38	145.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158380_k127_2977512_7	1459636.NTE_01188	3.191e-129	423.0	COG0520@1|root,arCOG00065@2157|Archaea,41SYH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158380_k127_2977512_42	1459636.NTE_01189	3.423e-24	109.0	arCOG08028@1|root,arCOG08028@2157|Archaea,41SWE@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2985769_0	373994.Riv7116_6000	2.759e-15	83.0	COG2931@1|root,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
SRR25158380_k127_2986732_3	1459636.NTE_02431	1.197e-40	166.0	COG1196@1|root,arCOG00371@2157|Archaea	2157|Archaea	D	Required for chromosome condensation and partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2986732_5	1459636.NTE_01460	2.043e-28	121.0	COG1374@1|root,arCOG00993@2157|Archaea	2157|Archaea	J	Protein involved in ribosomal biogenesis, contains PUA domain	-	-	-	ko:K07565	-	-	-	-	ko00000,ko03009	-	-	-	UPF0113
SRR25158380_k127_2986732_0	1459636.NTE_01459	6.754e-89	304.0	COG0144@1|root,arCOG00973@2157|Archaea	2157|Archaea	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
SRR25158380_k127_2986732_7	1408422.JHYF01000001_gene2875	6.674e-07	61.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,36FRJ@31979|Clostridiaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158380_k127_2986732_1	1459636.NTE_00846	5.73e-59	213.0	COG1994@1|root,COG3582@1|root,arCOG00614@2157|Archaea,arCOG01769@2157|Archaea,41SUB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-AN1
SRR25158380_k127_2986732_2	436308.Nmar_0506	4.399e-41	159.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41T0Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2986732_4	1459636.NTE_00900	1.011e-35	140.0	COG0517@1|root,arCOG00606@2157|Archaea,41T8N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_2992875_0	1120965.AUBV01000005_gene1570	3.734e-15	81.0	COG2133@1|root,COG2133@2|Bacteria,4PN3W@976|Bacteroidetes,47Y98@768503|Cytophagia	976|Bacteroidetes	G	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158380_k127_2992875_2	1459636.NTE_00006	0.0003197	48.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_2997533_0	330214.NIDE1052	3.961e-24	107.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158380_k127_2997533_1	1489678.RDMS_12480	0.0007807	45.0	COG2323@1|root,COG2323@2|Bacteria	2|Bacteria	K	membrane	ycaP	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158380_k127_2998202_1	589924.Ferp_1638	6.409e-56	203.0	COG2152@1|root,arCOG04084@2157|Archaea,2XZSX@28890|Euryarchaeota	28890|Euryarchaeota	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158380_k127_2998202_0	247490.KSU1_C0752	2.236e-87	297.0	COG1488@1|root,COG1488@2|Bacteria,2IXDA@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158380_k127_3004793_1	436308.Nmar_1769	7.884e-05	45.0	COG0531@1|root,arCOG00009@2157|Archaea,41SXX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158380_k127_3004793_0	1459636.NTE_00905	2.016e-87	294.0	COG1814@1|root,arCOG01096@2157|Archaea,41T0M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158380_k127_3006243_0	525904.Tter_1369	3.046e-36	143.0	COG0387@1|root,COG0387@2|Bacteria,2NQA1@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	cax	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iJN678.slr1336	Na_Ca_ex
SRR25158380_k127_3010415_0	644281.MFS40622_1531	3.667e-13	75.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_3022553_16	1459636.NTE_01277	5.442e-72	245.0	COG1522@1|root,arCOG01580@2157|Archaea,41SJD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
SRR25158380_k127_3022553_19	1459636.NTE_01274	4.519e-50	183.0	arCOG08745@1|root,arCOG08745@2157|Archaea,41SU1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3022553_26	1459636.NTE_00715	7.319e-28	115.0	COG2058@1|root,arCOG04287@2157|Archaea,41SP0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	-	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
SRR25158380_k127_3022553_9	1459636.NTE_02020	3.505e-119	392.0	COG0530@1|root,arCOG02881@2157|Archaea	2157|Archaea	P	COG0530 Ca2 Na antiporter	nce1	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158380_k127_3022553_13	1459636.NTE_00711	3.564e-84	284.0	COG0081@1|root,arCOG04289@2157|Archaea,41SHF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158380_k127_3022553_10	1459636.NTE_00712	6e-110	362.0	COG0244@1|root,arCOG04288@2157|Archaea,41S9R@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158380_k127_3022553_3	1459636.NTE_01900	1.103e-191	612.0	COG0323@1|root,arCOG01166@2157|Archaea	2157|Archaea	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
SRR25158380_k127_3022553_12	1459636.NTE_01899	3.172e-85	286.0	COG0638@1|root,arCOG00970@2157|Archaea,41SGS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158380_k127_3022553_4	1459636.NTE_02917	3.227e-180	571.0	COG0372@1|root,arCOG04237@2157|Archaea,41SAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM 2-methylcitrate synthase citrate synthase II	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158380_k127_3022553_23	1131266.ARWQ01000002_gene426	9.559e-38	147.0	COG2016@1|root,arCOG00985@2157|Archaea,41SSC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PUA domain	-	-	-	ko:K07575	-	-	-	-	ko00000	-	-	-	PUA
SRR25158380_k127_3022553_21	1459636.NTE_01724	2.459e-42	164.0	COG0468@1|root,arCOG00417@2157|Archaea,41SQC@651137|Thaumarchaeota	651137|Thaumarchaeota	T	RecA RadA	-	-	-	ko:K04482,ko:K04483	ko03440,ko03460,ko05200,ko05212,map03440,map03460,map05200,map05212	-	-	-	ko00000,ko00001,ko03400,ko04121,ko04131	-	-	-	Rad51
SRR25158380_k127_3022553_25	1459636.NTE_01725	2.585e-31	126.0	COG1958@1|root,arCOG00998@2157|Archaea,41SS5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
SRR25158380_k127_3022553_2	1459636.NTE_01726	1.942e-193	608.0	COG0192@1|root,arCOG07444@2157|Archaea,41S5P@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosylmethionine synthetase	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158380_k127_3022553_20	5827.XP_004221273.1	2.771e-46	178.0	COG0478@1|root,KOG2268@2759|Eukaryota,3Y9TI@5794|Apicomplexa,3KAA8@422676|Aconoidasida,3YX5G@5819|Haemosporida	422676|Aconoidasida	T	Rio2, N-terminal	-	-	2.7.11.1	ko:K07179	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1,Rio2_N
SRR25158380_k127_3022553_6	1459636.NTE_01728	2.426e-147	476.0	COG1903@1|root,arCOG04383@2157|Archaea,41S70@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
SRR25158380_k127_3022553_8	1459636.NTE_01732	2.756e-131	427.0	COG2073@1|root,arCOG00651@2157|Archaea,41S83@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin synthesis G C-terminus	-	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid
SRR25158380_k127_3022553_14	1459636.NTE_01733	4.47e-83	282.0	COG2082@1|root,COG2138@1|root,arCOG02246@2157|Archaea,arCOG02247@2157|Archaea,41SH6@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Cobalt chelatase (CbiK)	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiX
SRR25158380_k127_3022553_18	1459636.NTE_01733	2.095e-67	236.0	COG2082@1|root,COG2138@1|root,arCOG02246@2157|Archaea,arCOG02247@2157|Archaea,41SH6@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Cobalt chelatase (CbiK)	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiX
SRR25158380_k127_3022553_24	98439.AJLL01000070_gene1491	2.18e-32	132.0	COG4891@1|root,COG4891@2|Bacteria	2|Bacteria	K	PFAM Polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158380_k127_3022553_22	211165.AJLN01000145_gene1213	4.298e-39	147.0	COG2343@1|root,COG2343@2|Bacteria,1G7U6@1117|Cyanobacteria,1JIWP@1189|Stigonemataceae	1117|Cyanobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158380_k127_3022553_11	436308.Nmar_1079	4.331e-90	307.0	COG1063@1|root,arCOG01459@2157|Archaea,41S98@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_3022553_7	1459636.NTE_01734	2.417e-142	466.0	COG1797@1|root,arCOG00106@2157|Archaea,41SBP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
SRR25158380_k127_3022553_5	1459636.NTE_02485	4.843e-171	554.0	COG0322@1|root,arCOG04753@2157|Archaea,41SX9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TIGRFAM excinuclease ABC, C subunit	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
SRR25158380_k127_3022553_0	1459636.NTE_02484	0.0	1361.0	COG0178@1|root,arCOG04694@2157|Archaea,41T01@651137|Thaumarchaeota	651137|Thaumarchaeota	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158380_k127_3022553_1	1459636.NTE_02483	1.555e-298	927.0	COG0556@1|root,arCOG04748@2157|Archaea,41T0H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158380_k127_3022553_17	1459636.NTE_02473	6.045e-72	246.0	COG0526@1|root,arCOG00314@2157|Archaea,41SKE@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158380_k127_3022553_15	1459636.NTE_03037	6.653e-77	263.0	COG2220@1|root,arCOG00497@2157|Archaea	2157|Archaea	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158380_k127_3022796_1	526222.Desal_3740	1.848e-46	179.0	COG0596@1|root,COG0596@2|Bacteria,1QW7Y@1224|Proteobacteria,43D1K@68525|delta/epsilon subdivisions,2X89J@28221|Deltaproteobacteria,2MHE2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158380_k127_3022796_0	1459636.NTE_01648	2.943e-189	596.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_3061943_6	1459636.NTE_03520	1.052e-41	162.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3061943_3	1459636.NTE_01186	2.032e-58	210.0	COG1878@1|root,arCOG02462@2157|Archaea,41SK8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158380_k127_3061943_2	1459636.NTE_00866	8.851e-66	230.0	COG1392@1|root,arCOG02640@2157|Archaea,41SKJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158380_k127_3061943_0	1459636.NTE_00865	1.009e-155	498.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158380_k127_3061943_4	1459636.NTE_02862	1.545e-49	185.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_3061943_5	1459636.NTE_03191	7.253e-42	163.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_3061943_7	1229909.NSED_00455	1.122e-40	160.0	COG0500@1|root,arCOG04347@2157|Archaea,41SQN@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Nodulation protein S (NodS)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158380_k127_3061943_1	1459636.NTE_02280	4.437e-68	239.0	COG1575@1|root,arCOG00480@2157|Archaea,41SNA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3061943_10	1459636.NTE_02279	4.429e-15	81.0	COG3161@1|root,arCOG01031@2157|Archaea	2157|Archaea	H	4-hydroxybenzoate synthetase (chorismate lyase)	-	-	2.4.2.54,4.1.3.40	ko:K03181,ko:K06984	ko00130,ko00790,ko01100,ko01110,map00130,map00790,map01100,map01110	M00117	R01302,R10337,R11102	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF98,GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_3061943_12	1459636.NTE_01872	2.69e-12	69.0	COG1801@1|root,arCOG04291@2157|Archaea	2157|Archaea	L	DUF72 domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_3061943_8	1229909.NSED_01010	3.249e-28	116.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_3117426_5	224324.aq_926	0.0004362	43.0	COG1801@1|root,COG1801@2|Bacteria,2G44R@200783|Aquificae	200783|Aquificae	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_3117426_4	1267533.KB906736_gene1024	2.975e-13	75.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3117426_3	1459636.NTE_00669	1.618e-13	81.0	COG3685@1|root,arCOG11147@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158380_k127_3117426_0	1459636.NTE_02294	5.645e-58	205.0	COG1321@1|root,arCOG02100@2157|Archaea,41SQ9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
SRR25158380_k127_3117426_1	436308.Nmar_1130	4.852e-54	194.0	COG0428@1|root,arCOG00576@2157|Archaea,41S6R@651137|Thaumarchaeota	651137|Thaumarchaeota	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3129147_1	1459636.NTE_03221	1.623e-62	226.0	COG0500@1|root,arCOG01783@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158380_k127_3129147_4	335543.Sfum_2534	9.57e-05	46.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,42PSS@68525|delta/epsilon subdivisions,2WKGZ@28221|Deltaproteobacteria,2MRJA@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	HARE-HTH,Mrr_N,Mrr_cat
SRR25158380_k127_3129147_3	146922.JOFU01000012_gene1787	8.08e-09	68.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
SRR25158380_k127_3129147_2	247490.KSU1_C1274	1.363e-27	129.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_3129147_0	1459636.NTE_03048	4.007e-67	236.0	COG1938@1|root,arCOG00347@2157|Archaea,41T2Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158380_k127_313767_0	1459636.NTE_00487	6.053e-70	246.0	COG1475@1|root,arCOG11113@2157|Archaea	2157|Archaea	K	TIGRFAM ParB RepB Spo0J family partition protein	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158380_k127_313767_1	1459636.NTE_00845	6.712e-08	65.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3173208_1	1459636.NTE_02850	8.043e-28	121.0	arCOG08794@1|root,arCOG08794@2157|Archaea,41SR7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3173208_0	1459636.NTE_02845	2.782e-39	152.0	COG3398@1|root,arCOG02611@2157|Archaea,41T7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158380_k127_3173208_2	1459636.NTE_02846	2.644e-14	76.0	arCOG07573@1|root,arCOG07573@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3174351_2	1459636.NTE_02192	1.802e-21	95.0	COG1249@1|root,arCOG01068@2157|Archaea	2157|Archaea	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_3174351_0	671065.MetMK1DRAFT_00008850	1.687e-46	173.0	COG1335@1|root,arCOG01943@2157|Archaea,2XQK1@28889|Crenarchaeota	28889|Crenarchaeota	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158380_k127_3174351_1	1158345.JNLL01000001_gene808	2.507e-39	153.0	COG1488@1|root,COG1488@2|Bacteria,2G3U2@200783|Aquificae	200783|Aquificae	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158380_k127_3189406_0	1459636.NTE_01024	3.205e-23	108.0	arCOG03788@1|root,arCOG03788@2157|Archaea,41T96@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3201074_0	1463853.JOHW01000041_gene5534	4.367e-100	339.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158380_k127_3201074_2	1459636.NTE_02677	1.431e-48	180.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3201074_3	443144.GM21_2393	1.59e-27	122.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3201074_5	1459636.NTE_02412	1.318e-15	79.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_3201074_1	1459636.NTE_02673	1.825e-90	302.0	arCOG01449@1|root,arCOG01449@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3201074_4	861299.J421_1879	7.525e-26	115.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_3205313_2	1121434.AULY01000008_gene140	1.026e-07	58.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43BN0@68525|delta/epsilon subdivisions,2X702@28221|Deltaproteobacteria,2MH9Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158380_k127_3205313_1	436308.Nmar_1599	8.782e-15	74.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3205313_0	1459636.NTE_01411	2.362e-39	152.0	arCOG10404@1|root,arCOG10404@2157|Archaea	1459636.NTE_01411|-	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3205350_1	1459636.NTE_00427	1.378e-21	102.0	arCOG06357@1|root,arCOG06357@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3205350_0	1459636.NTE_01334	9.786e-76	261.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_3205350_3	1229909.NSED_05640	5.274e-10	63.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158380_k127_3205350_5	1294265.JCM21738_4929	7.086e-07	58.0	COG5012@1|root,COG5012@2|Bacteria,1UIJC@1239|Firmicutes,4ISK1@91061|Bacilli,1ZSBS@1386|Bacillus	91061|Bacilli	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158380_k127_3205350_4	436308.Nmar_0188	6.707e-07	57.0	COG4276@1|root,arCOG04604@2157|Archaea,41SI9@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158380_k127_3205350_2	1459636.NTE_00830	3.121e-12	71.0	COG3324@1|root,arCOG04946@2157|Archaea	2157|Archaea	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_3205350_6	273063.STK_16880	0.0001088	45.0	arCOG07723@1|root,arCOG07723@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3276215_28	1459636.NTE_01087	3.174e-12	66.0	COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_3276215_18	1459636.NTE_01851	2.527e-59	214.0	COG0730@1|root,arCOG02050@2157|Archaea,41SKY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158380_k127_3276215_6	1459636.NTE_01853	5.11e-155	496.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
SRR25158380_k127_3276215_17	1459636.NTE_01764	2.825e-73	251.0	COG1676@1|root,arCOG01701@2157|Archaea,41SHW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
SRR25158380_k127_3276215_29	178306.PAE0804	1.151e-11	67.0	COG1383@1|root,arCOG01885@2157|Archaea,2XRGM@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
SRR25158380_k127_3276215_26	1459636.NTE_02377	7.397e-15	77.0	COG1617@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG02197@2157|Archaea,41SSW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Kinase binding protein CGI-121	-	-	-	-	-	-	-	-	-	-	-	-	CGI-121,ThiS
SRR25158380_k127_3276215_27	1229909.NSED_07835	9.49e-13	75.0	COG1617@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG02197@2157|Archaea,41SSW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Kinase binding protein CGI-121	-	-	-	-	-	-	-	-	-	-	-	-	CGI-121,ThiS
SRR25158380_k127_3276215_21	1459636.NTE_01949	1.024e-51	194.0	COG0722@1|root,arCOG00245@2157|Archaea,41SM0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158380_k127_3276215_9	1459636.NTE_01950	8.892e-146	475.0	COG0436@1|root,COG1605@1|root,arCOG01130@2157|Archaea,arCOG02098@2157|Archaea,41SBV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Chorismate mutase type II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,CM_2
SRR25158380_k127_3276215_5	1459636.NTE_01951	5.76e-174	552.0	COG0082@1|root,arCOG04133@2157|Archaea,41SC3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158380_k127_3276215_10	1459636.NTE_01952	7.288e-142	462.0	COG0128@1|root,arCOG04134@2157|Archaea,41S5I@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158380_k127_3276215_16	1459636.NTE_01953	2.833e-85	290.0	COG1685@1|root,arCOG01025@2157|Archaea,41SGZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_3276215_15	1459636.NTE_01954	1.203e-96	323.0	COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158380_k127_3276215_20	1229909.NSED_02795	2.601e-56	205.0	COG0169@1|root,arCOG02097@2157|Archaea,41SKU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
SRR25158380_k127_3276215_8	1459636.NTE_01958	1.962e-148	473.0	COG0863@1|root,arCOG00115@2157|Archaea,41SZP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158380_k127_3276215_11	1459636.NTE_01959	2.756e-131	427.0	COG1465@1|root,arCOG04353@2157|Archaea,41S88@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
SRR25158380_k127_3276215_12	1459636.NTE_01960	7.737e-128	413.0	COG1830@1|root,arCOG04044@2157|Archaea,41SCP@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158380_k127_3276215_19	387631.Asulf_01997	1.78e-58	213.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158380_k127_3276215_13	1459636.NTE_02880	8.957e-121	397.0	COG0150@1|root,arCOG00639@2157|Archaea,41SEE@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_3276215_1	1459636.NTE_02878	5.499e-238	746.0	COG1384@1|root,arCOG00485@2157|Archaea,41SB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158380_k127_3276215_3	1459636.NTE_02879	2.454e-207	659.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
SRR25158380_k127_3276215_14	1459636.NTE_02874	3.679e-100	335.0	COG2404@1|root,arCOG00423@2157|Archaea	2157|Archaea	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_3276215_22	1229909.NSED_07825	1.324e-43	166.0	COG0009@1|root,arCOG01952@2157|Archaea,41SPF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Sua5 YciO YrdC YwlC family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158380_k127_3276215_25	1459636.NTE_02378	4.286e-37	147.0	COG1818@1|root,arCOG00084@2157|Archaea,41SNW@651137|Thaumarchaeota	651137|Thaumarchaeota	S	THUMP domain	-	-	-	ko:K06963	-	-	-	-	ko00000,ko03016	-	-	-	THUMP
SRR25158380_k127_3276215_7	1459636.NTE_00009	3.797e-151	482.0	COG0540@1|root,arCOG00911@2157|Archaea,41S6H@651137|Thaumarchaeota	651137|Thaumarchaeota	F	aspartate carbamoyltransferase	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158380_k127_3276215_0	1459636.NTE_00110	0.0	1392.0	COG0209@1|root,arCOG01917@1|root,arCOG03713@1|root,arCOG01917@2157|Archaea,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,41SAH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158380_k127_3276215_4	436308.Nmar_1628	1.02e-190	618.0	COG0640@1|root,COG1328@1|root,arCOG00734@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota	651137|Thaumarchaeota	FK	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,HTH_20,NRDD
SRR25158380_k127_3276215_24	1459636.NTE_00108	3.739e-37	149.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
SRR25158380_k127_3276215_23	1459636.NTE_00105	3.73e-40	152.0	COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota	651137|Thaumarchaeota	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158380_k127_3276215_2	1459636.NTE_00104	1.877e-216	675.0	COG0183@1|root,arCOG01278@2157|Archaea,41SCI@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158380_k127_3311675_1	1459636.NTE_02865	1.398e-12	71.0	arCOG10406@1|root,arCOG10406@2157|Archaea,41SVU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger, C2H2 type	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2
SRR25158380_k127_3311675_0	1459636.NTE_00770	3.911e-57	202.0	COG0231@1|root,arCOG04277@2157|Archaea,41SNP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	-	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	eIF-5a
SRR25158380_k127_3311675_2	1107311.Q767_11610	2.435e-09	68.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,1HYRX@117743|Flavobacteriia,2NST0@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_331177_1	632335.Calkr_1166	5.646e-67	236.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,42G6K@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158380_k127_331177_0	1459636.NTE_03132	2.167e-76	261.0	COG0715@1|root,arCOG01803@2157|Archaea,41SG5@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158380_k127_3318560_0	269797.Mbar_A3220	2.405e-63	226.0	COG1842@1|root,arCOG04782@2157|Archaea,2XU11@28890|Euryarchaeota,2N9P1@224756|Methanomicrobia	224756|Methanomicrobia	K	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158380_k127_3318560_1	1353276.JADR01000001_gene281	1.048e-10	70.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
SRR25158380_k127_3335964_5	1227484.C471_09705	1.916e-09	66.0	arCOG03919@1|root,arCOG03919@2157|Archaea,2XUDK@28890|Euryarchaeota,23TJR@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRR25158380_k127_3335964_2	436308.Nmar_1498	1.229e-15	81.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3335964_1	1459636.NTE_00004	4.479e-18	92.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158380_k127_3335964_6	1459636.NTE_00005	2.063e-06	53.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3335964_3	1459636.NTE_00006	5.451e-14	74.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3335964_0	1459636.NTE_00007	3.285e-224	718.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
SRR25158380_k127_3340529_0	247490.KSU1_D0999	1.401e-24	116.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_3347314_3	1459636.NTE_01186	8.382e-23	102.0	COG1878@1|root,arCOG02462@2157|Archaea,41SK8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158380_k127_3347314_2	1459636.NTE_03520	4.162e-52	195.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3347314_1	342949.PNA2_0513	7.201e-113	392.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,243CX@183968|Thermococci	183968|Thermococci	L	ERCC4 domain	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,Helicase_C
SRR25158380_k127_3347314_0	1459636.NTE_03346	5.755e-161	518.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	rad25	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158380_k127_3347314_4	1459636.NTE_02174	1.268e-06	55.0	COG1715@1|root,arCOG02777@2157|Archaea	2157|Archaea	V	restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
SRR25158380_k127_3389645_1	1348657.M622_14460	2.376e-15	79.0	COG3467@1|root,COG3467@2|Bacteria,1N17U@1224|Proteobacteria	1224|Proteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_3389645_0	926561.KB900617_gene1965	2.998e-101	336.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WBJA@53433|Halanaerobiales	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158380_k127_3389645_2	374847.Kcr_0237	5.554e-07	51.0	COG4670@1|root,arCOG01986@2157|Archaea	2157|Archaea	I	Acyl CoA acetate 3-ketoacid CoA transferase	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158380_k127_3392015_1	1459636.NTE_02844	2.885e-15	81.0	arCOG08825@1|root,arCOG08825@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3392015_0	1459636.NTE_01850	1.552e-231	730.0	COG1028@1|root,arCOG01259@2157|Archaea,41S7V@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_3482620_0	756499.Desde_1915	1.365e-12	70.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,263HH@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_3482620_1	1459636.NTE_02333	1.888e-12	73.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3484902_2	1459636.NTE_02210	1.579e-83	286.0	COG0010@1|root,arCOG01700@2157|Archaea,41T23@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158380_k127_3484902_1	1459636.NTE_01522	2.093e-164	527.0	COG1960@1|root,arCOG01707@2157|Archaea	2157|Archaea	I	COG1960 Acyl-CoA dehydrogenases	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158380_k127_3484902_0	1459636.NTE_02036	7.247e-243	755.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
SRR25158380_k127_3484902_3	1459636.NTE_03538	7.374e-74	259.0	COG0506@1|root,arCOG06322@2157|Archaea,41SY1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158380_k127_3484902_11	558152.IQ37_03790	0.0001472	51.0	COG0794@1|root,COG2905@1|root,COG0794@2|Bacteria,COG2905@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia,3ZPIK@59732|Chryseobacterium	976|Bacteroidetes	MT	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR25158380_k127_3484902_6	1459636.NTE_01989	4.015e-52	188.0	COG1832@1|root,arCOG04227@2157|Archaea,41SMT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158380_k127_3484902_7	479434.Sthe_0450	2.598e-21	108.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158380_k127_3484902_5	219305.MCAG_00296	6.391e-53	210.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158380_k127_3484902_10	436308.Nmar_1194	0.0001278	45.0	arCOG08693@1|root,arCOG08693@2157|Archaea,41T7N@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3484902_4	1158338.JNLJ01000005_gene1373	2.79e-69	245.0	COG0338@1|root,COG0338@2|Bacteria,2G4QA@200783|Aquificae	200783|Aquificae	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158380_k127_3486225_0	1459636.NTE_00264	2.383e-139	451.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158380_k127_3486225_2	1459636.NTE_02123	1.968e-91	324.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158380_k127_3486225_1	1459636.NTE_02717	4.23e-132	429.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158380_k127_3499868_1	1459636.NTE_00441	2.635e-43	170.0	COG0454@1|root,arCOG00845@2157|Archaea,41T5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158380_k127_3499868_0	1459636.NTE_01638	3.153e-123	407.0	COG1602@1|root,arCOG04269@2157|Archaea,41S7H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archaeal Nre, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
SRR25158380_k127_3502306_2	1459636.NTE_03075	4.171e-52	186.0	2DZ95@1|root,2N5MX@2157|Archaea,41T90@651137|Thaumarchaeota	1459636.NTE_03075|-	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	-
SRR25158380_k127_3502306_3	1190606.AJYG01000194_gene2691	3.957e-16	89.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XWTA@135623|Vibrionales	135623|Vibrionales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,HemolysinCabind
SRR25158380_k127_3502306_4	440512.C211_14001	3.016e-13	71.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158380_k127_3502306_0	1459636.NTE_03481	1.755e-171	559.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158380_k127_3502306_1	436308.Nmar_1457	2.577e-126	413.0	arCOG01778@1|root,arCOG01778@2157|Archaea,41SXW@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158380_k127_3502306_6	589924.Ferp_1587	0.0003134	46.0	arCOG10363@1|root,arCOG10363@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3507194_0	886293.Sinac_1873	5.106e-89	297.0	COG1028@1|root,COG1028@2|Bacteria,2IZED@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158380_k127_3507194_2	1459636.NTE_01187	4.347e-10	63.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158380_k127_3513653_1	391587.KAOT1_19772	5.255e-77	269.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_3513653_2	1459636.NTE_02436	3.44e-74	266.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
SRR25158380_k127_3513653_0	1459636.NTE_03092	1.469e-95	327.0	COG3408@1|root,arCOG03287@2157|Archaea	2157|Archaea	G	Glycogen debranching enzyme	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	GDE_C,GDE_N_bis,Trehalase
SRR25158380_k127_3513653_5	1041146.ATZB01000034_gene587	8.506e-07	60.0	COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,2TSRA@28211|Alphaproteobacteria,4B7PT@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	GXGXG motif	glxC	-	2.1.1.21	ko:K22082	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG
SRR25158380_k127_3513653_4	868131.MSWAN_1789	2.342e-41	163.0	COG0067@1|root,arCOG00095@2157|Archaea,2XUF6@28890|Euryarchaeota,23PBU@183925|Methanobacteria	183925|Methanobacteria	E	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GATase_7
SRR25158380_k127_3513653_6	565033.GACE_0276	0.0002134	53.0	COG0069@1|root,COG1145@1|root,arCOG00619@2157|Archaea,arCOG02187@2157|Archaea,2Y7H6@28890|Euryarchaeota,245Q2@183980|Archaeoglobi	183980|Archaeoglobi	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_syn_central,Glu_synthase
SRR25158380_k127_3513653_3	565033.GACE_0276	9.015e-73	264.0	COG0069@1|root,COG1145@1|root,arCOG00619@2157|Archaea,arCOG02187@2157|Archaea,2Y7H6@28890|Euryarchaeota,245Q2@183980|Archaeoglobi	183980|Archaeoglobi	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_syn_central,Glu_synthase
SRR25158380_k127_3516682_0	1229909.NSED_01010	1.984e-15	76.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_3518714_4	1459636.NTE_01001	6.856e-54	196.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3518714_1	1459636.NTE_01021	6.826e-88	304.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_3518714_3	1459636.NTE_01632	9.836e-63	224.0	COG0518@1|root,arCOG00090@2157|Archaea,41T3Z@651137|Thaumarchaeota	651137|Thaumarchaeota	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158380_k127_3518714_5	194439.CT0933	2.971e-06	55.0	COG4276@1|root,COG4276@2|Bacteria,1FE5K@1090|Chlorobi	1090|Chlorobi	S	PFAM cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3518714_0	1459636.NTE_02605	2.438e-315	982.0	COG0464@1|root,arCOG01308@2157|Archaea,41SX8@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_3518714_2	1459636.NTE_00092	2.234e-85	293.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	1459636.NTE_00092|-	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158380_k127_3549442_3	1459636.NTE_00648	2.596e-68	237.0	COG0293@1|root,arCOG00079@2157|Archaea,41SIK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
SRR25158380_k127_3549442_1	1459636.NTE_00645	7.462e-279	862.0	COG2368@1|root,arCOG02143@2157|Archaea,41SA0@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Vinylacetyl-CoA Delta-isomerase	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
SRR25158380_k127_3549442_2	591019.Shell_0853	4.599e-83	287.0	COG4608@1|root,arCOG00184@2157|Archaea,2XQ0S@28889|Crenarchaeota	28889|Crenarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter	dppF	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158380_k127_3549442_0	1459636.NTE_01644	2.264e-288	924.0	COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota	651137|Thaumarchaeota	D	SMC proteins Flexible Hinge Domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158380_k127_3549442_4	1459636.NTE_01650	4.001e-37	141.0	COG1581@1|root,arCOG01753@2157|Archaea	2157|Archaea	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
SRR25158380_k127_3551538_0	1459636.NTE_02436	9.105e-69	251.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
SRR25158380_k127_3551538_3	1120966.AUBU01000002_gene2349	2.47e-16	85.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158380_k127_3551538_2	262724.TT_C1879	1.2e-26	116.0	COG0433@1|root,COG0433@2|Bacteria,1WME2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3551538_1	1499967.BAYZ01000120_gene3422	2.322e-39	160.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	HAS-barrel
SRR25158380_k127_3551538_4	1379698.RBG1_1C00001G1210	1.422e-11	70.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158380_k127_3551708_5	1459636.NTE_00881	3.032e-12	71.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_3551708_1	570952.ATVH01000014_gene2038	1.575e-134	444.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2JPBR@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158380_k127_3551708_4	1469557.JSWF01000017_gene2333	1.507e-12	74.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1I30B@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxyl carrier protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
SRR25158380_k127_3551708_3	1459636.NTE_02018	1.376e-15	81.0	COG0589@1|root,arCOG02053@2157|Archaea,41T7V@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_3551708_0	1459636.NTE_01678	1.466e-147	480.0	COG0126@1|root,arCOG00496@2157|Archaea,41SMB@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158380_k127_3551708_2	1229909.NSED_02125	4.43e-65	233.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3569906_4	273075.Ta1186	8.518e-32	132.0	COG2345@1|root,arCOG01692@2157|Archaea	2157|Archaea	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158380_k127_3569906_5	1405.DJ92_5035	7.505e-31	125.0	2DNMG@1|root,32Y46@2|Bacteria,1VK1T@1239|Firmicutes,4HNYW@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3569906_7	1463825.JNXC01000031_gene1602	6.211e-24	108.0	COG1853@1|root,COG1853@2|Bacteria,2IE1Z@201174|Actinobacteria	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158380_k127_3569906_0	1341151.ASZU01000004_gene77	7.846e-97	327.0	COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,4HCEG@91061|Bacilli,27CIM@186824|Thermoactinomycetaceae	91061|Bacilli	S	BNR/Asp-box repeat	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158380_k127_3569906_3	1200792.AKYF01000007_gene840	9.051e-38	154.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158380_k127_3569906_1	1174528.JH992893_gene5996	2.045e-89	304.0	COG0596@1|root,COG0596@2|Bacteria,1G6JI@1117|Cyanobacteria,1JMVF@1189|Stigonemataceae	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158380_k127_3569906_6	1459636.NTE_00447	6.177e-26	118.0	COG3832@1|root,arCOG05261@2157|Archaea	2157|Archaea	H	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158380_k127_3569906_8	1459636.NTE_00446	7.041e-24	104.0	COG0640@1|root,arCOG01681@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158380_k127_3569906_2	1028800.RG540_CH39100	5.944e-47	172.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,4BDVS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158380_k127_3591441_1	1459636.NTE_00648	2.426e-71	246.0	COG0293@1|root,arCOG00079@2157|Archaea,41SIK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
SRR25158380_k127_3591441_0	1459636.NTE_00833	1.424e-95	318.0	COG0778@1|root,arCOG00288@2157|Archaea,41S7D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cob(II)yrinic acid a,c-diamide reductase	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
SRR25158380_k127_3595505_0	1254432.SCE1572_33005	2.311e-05	52.0	COG3064@1|root,COG3064@2|Bacteria,1QX6Z@1224|Proteobacteria,43BZQ@68525|delta/epsilon subdivisions,2X7AH@28221|Deltaproteobacteria,2YZHQ@29|Myxococcales	28221|Deltaproteobacteria	M	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158380_k127_36312_0	795359.TOPB45_1316	0.0001207	47.0	COG1522@1|root,COG1522@2|Bacteria,2GI4U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158380_k127_3668223_17	1131266.ARWQ01000008_gene334	1.578e-67	239.0	COG0483@1|root,arCOG01349@2157|Archaea,41SIF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158380_k127_3668223_30	1459636.NTE_01553	3.697e-34	134.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3668223_39	8010.XP_010879480.1	1.817e-06	57.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata,496SD@7742|Vertebrata,49XMF@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
SRR25158380_k127_3668223_34	1459636.NTE_03491	2.406e-14	76.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_3668223_40	368408.Tpen_0769	1.077e-05	50.0	COG0640@1|root,arCOG03859@2157|Archaea	2157|Archaea	K	ligase activity	-	-	-	ko:K00666,ko:K03892	-	-	-	-	ko00000,ko01000,ko01004,ko03000	-	-	-	HTH_20,HTH_5
SRR25158380_k127_3668223_4	1459636.NTE_01908	4.225e-160	511.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158380_k127_3668223_15	1459636.NTE_01717	9.258e-70	241.0	arCOG08639@1|root,arCOG08639@2157|Archaea,41SP8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3668223_12	1459636.NTE_01562	1.305e-74	260.0	COG0457@1|root,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
SRR25158380_k127_3668223_11	1459636.NTE_00439	5.396e-76	258.0	COG2131@1|root,arCOG01487@2157|Archaea,41SHS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158380_k127_3668223_14	1459636.NTE_00433	2.301e-70	243.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3668223_2	1459636.NTE_01048	1.125e-190	605.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158380_k127_3668223_0	1459636.NTE_01051	1.198e-316	983.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S6N@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18593	ko00720,ko01120,map00720,map01120	-	R10758	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158380_k127_3668223_19	1459636.NTE_01054	1.896e-60	220.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158380_k127_3668223_5	1459636.NTE_03297	1.31e-133	437.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158380_k127_3668223_10	1459636.NTE_00095	1.414e-80	271.0	COG1675@1|root,arCOG04270@2157|Archaea,41SJ8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
SRR25158380_k127_3668223_18	1459636.NTE_03545	1.246e-65	230.0	COG1985@1|root,arCOG01484@2157|Archaea,41SK2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
SRR25158380_k127_3668223_7	1459636.NTE_03546	1.009e-113	381.0	COG0402@1|root,arCOG00692@2157|Archaea,41S61@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158380_k127_3668223_16	1459636.NTE_03547	3.482e-68	240.0	COG2429@1|root,arCOG04202@2157|Archaea,41SHK@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity	gch3	-	3.5.4.29	ko:K08096	ko00740,ko01100,map00740,map01100	-	R07306	RC01790	ko00000,ko00001,ko01000	-	-	-	GCH_III
SRR25158380_k127_3668223_24	1459636.NTE_03548	2.274e-45	168.0	COG0054@1|root,arCOG01323@2157|Archaea,41SQ6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158380_k127_3668223_9	1459636.NTE_03549	4.462e-86	292.0	COG0108@1|root,arCOG01320@2157|Archaea,41SFW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
SRR25158380_k127_3668223_21	1459636.NTE_03551	9.583e-59	210.0	COG0307@1|root,arCOG04713@2157|Archaea,41SKQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	riboflavin synthase, alpha	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158380_k127_3668223_1	1459636.NTE_02933	2.198e-245	764.0	COG1690@1|root,arCOG04246@2157|Archaea,41SE4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158380_k127_3668223_31	1459636.NTE_02934	9.863e-33	131.0	arCOG05529@1|root,arCOG05529@2157|Archaea,41SSJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	dsDNA_bind
SRR25158380_k127_3668223_13	1459636.NTE_02936	7.865e-74	249.0	COG0100@1|root,arCOG04240@2157|Archaea,41SII@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158380_k127_3668223_29	374847.Kcr_0043	1.899e-35	148.0	COG0611@1|root,arCOG00638@2157|Archaea	2157|Archaea	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158380_k127_3668223_6	1459636.NTE_02946	9.606e-126	416.0	COG1109@1|root,arCOG00767@2157|Archaea,41SC1@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_3668223_8	1459636.NTE_03347	4.976e-105	363.0	COG3372@1|root,arCOG04356@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
SRR25158380_k127_3668223_22	1459636.NTE_00456	8.088e-49	182.0	arCOG03142@1|root,arCOG03142@2157|Archaea,41T78@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3668223_33	1459636.NTE_02705	5.698e-17	85.0	arCOG08790@1|root,arCOG08790@2157|Archaea,41SWN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3668223_3	1459636.NTE_02706	9.401e-182	579.0	COG0043@1|root,arCOG01671@2157|Archaea,41SEQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158380_k127_3668223_41	643867.Ftrac_0495	0.0001093	52.0	COG2374@1|root,COG4447@1|root,COG4733@1|root,COG4886@1|root,COG2374@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
SRR25158380_k127_3668223_28	1459636.NTE_02478	8.32e-36	138.0	COG0836@1|root,arCOG02427@2157|Archaea	2157|Archaea	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0229	MannoseP_isomer,NTP_transferase
SRR25158380_k127_3668223_38	1476876.JOJO01000010_gene2972	3.06e-08	63.0	COG2931@1|root,COG2931@2|Bacteria,2IP5P@201174|Actinobacteria	201174|Actinobacteria	Q	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158380_k127_3668223_25	1459636.NTE_02995	4.991e-44	179.0	COG0582@1|root,arCOG01245@2157|Archaea,41T6H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158380_k127_3668223_35	1459636.NTE_00603	9.022e-11	66.0	arCOG08747@1|root,arCOG08747@2157|Archaea,41T48@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3671301_3	436308.Nmar_0978	2.529e-18	89.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158380_k127_3671301_0	436308.Nmar_0977	5.122e-127	421.0	COG0702@1|root,arCOG03015@2157|Archaea	2157|Archaea	GM	NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_10
SRR25158380_k127_3671301_2	1459636.NTE_02427	1.041e-19	96.0	arCOG06357@1|root,arCOG06357@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3671301_1	1232437.KL661977_gene3753	1.125e-105	359.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2MI2V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SRR25158380_k127_367418_13	1459636.NTE_01650	2.754e-20	91.0	COG1581@1|root,arCOG01753@2157|Archaea	2157|Archaea	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
SRR25158380_k127_367418_16	1229909.NSED_03315	3.174e-13	72.0	arCOG08668@1|root,arCOG08668@2157|Archaea,41SW4@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_367418_2	1459636.NTE_01675	3.576e-212	673.0	COG1199@1|root,arCOG00770@2157|Archaea,41T2V@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2
SRR25158380_k127_367418_6	1459636.NTE_02290	8.374e-109	359.0	COG0024@1|root,arCOG01001@2157|Archaea,41SEA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158380_k127_367418_3	1459636.NTE_02050	5.068e-169	541.0	COG3635@1|root,arCOG01696@2157|Archaea,41S6M@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158380_k127_367418_11	1459636.NTE_02186	4.596e-57	201.0	COG2522@1|root,arCOG00017@2157|Archaea,41SJZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transcriptional regulator	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_367418_1	1459636.NTE_02919	8.733e-213	663.0	COG2141@1|root,arCOG02410@2157|Archaea,41SBM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158380_k127_367418_7	1459636.NTE_02920	4.454e-106	354.0	COG1236@1|root,arCOG00545@2157|Archaea,41SYB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
SRR25158380_k127_367418_9	1459636.NTE_02921	8.78e-76	259.0	COG0299@1|root,arCOG02825@2157|Archaea,41SH3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosylglycinamide formyltransferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158380_k127_367418_15	1229909.NSED_06305	3.63e-19	90.0	COG5431@1|root,arCOG01120@2157|Archaea,41SW3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_367418_5	1459636.NTE_02169	2.671e-144	468.0	COG0151@1|root,arCOG04415@2157|Archaea,41SB3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158380_k127_367418_12	999411.HMPREF1092_02322	5.129e-32	132.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,36JPF@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158380_k127_367418_8	1459636.NTE_02167	2.966e-101	336.0	COG2759@1|root,arCOG04538@2157|Archaea,41S6B@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158380_k127_367418_10	1459636.NTE_02171	8.914e-62	221.0	COG1407@1|root,arCOG01150@2157|Archaea,41SJB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158380_k127_367418_0	1459636.NTE_02172	0.0	1466.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158380_k127_367418_18	436308.Nmar_1085	0.0008002	42.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158380_k127_367418_4	1459636.NTE_02173	6.454e-168	535.0	COG0505@1|root,arCOG00064@2157|Archaea,41SF0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158380_k127_367418_17	1120953.AUBH01000006_gene2616	2.85e-07	60.0	COG5184@1|root,COG5184@2|Bacteria,1QVUK@1224|Proteobacteria,1T2JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	REJ
SRR25158380_k127_3675365_0	1121935.AQXX01000064_gene3308	1.271e-127	413.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,1XPTW@135619|Oceanospirillales	135619|Oceanospirillales	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SRR25158380_k127_3675365_2	1459636.NTE_00144	1.245e-53	198.0	arCOG03593@1|root,arCOG03593@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795,PRC
SRR25158380_k127_3675365_1	1459636.NTE_01099	1.318e-98	328.0	COG1409@1|root,arCOG01153@2157|Archaea,41SF2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158380_k127_3686339_0	1232410.KI421418_gene2313	4.818e-70	252.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NK7@68525|delta/epsilon subdivisions,2WKTV@28221|Deltaproteobacteria,43RYC@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158380_k127_3687121_28	1459636.NTE_02263	1.761e-20	95.0	COG1608@1|root,arCOG00860@2157|Archaea,41SI4@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Amino acid kinase family	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158380_k127_3687121_5	1459636.NTE_02264	6.572e-147	473.0	COG1304@1|root,arCOG00613@2157|Archaea	2157|Archaea	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158380_k127_3687121_12	1459636.NTE_02265	1.986e-105	351.0	COG0142@1|root,arCOG01726@2157|Archaea,41SEV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158380_k127_3687121_1	1459636.NTE_02266	1.106e-219	695.0	COG0008@1|root,arCOG04302@2157|Archaea,41S5V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
SRR25158380_k127_3687121_9	1459636.NTE_02267	1.31e-131	425.0	COG0179@1|root,arCOG00235@2157|Archaea,41S5K@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158380_k127_3687121_4	1459636.NTE_02274	1.363e-147	471.0	COG1018@1|root,arCOG02200@2157|Archaea,41S72@651137|Thaumarchaeota	651137|Thaumarchaeota	C	oxidoreductase FAD NAD(P)-binding	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158380_k127_3687121_25	1459636.NTE_02275	1.872e-37	143.0	arCOG06055@1|root,arCOG06055@2157|Archaea,41SQ3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3687121_0	1459636.NTE_02276	8.3e-321	984.0	COG1032@1|root,arCOG01357@2157|Archaea,41S86@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158380_k127_3687121_23	1459636.NTE_02277	1.6e-45	168.0	COG0494@1|root,arCOG01078@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	apa	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
SRR25158380_k127_3687121_22	1459636.NTE_02283	6.58e-50	187.0	COG0533@1|root,arCOG01185@2157|Archaea	1459636.NTE_02283|-	F	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3687121_19	1459636.NTE_02284	6.468e-63	218.0	arCOG08652@1|root,arCOG08652@2157|Archaea,41SMZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3687121_17	1459636.NTE_02285	4.613e-83	286.0	COG1340@1|root,arCOG01159@2157|Archaea	2157|Archaea	D	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158380_k127_3687121_7	1459636.NTE_01749	4.88e-140	454.0	COG1819@1|root,arCOG01393@2157|Archaea,41SZK@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3687121_31	1459636.NTE_01750	1.968e-11	76.0	COG0301@1|root,arCOG00038@2157|Archaea,41ST5@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3687121_16	1459636.NTE_01968	3.552e-88	301.0	COG0457@1|root,arCOG03032@2157|Archaea,41T0V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
SRR25158380_k127_3687121_24	1459636.NTE_01967	3.757e-38	149.0	COG0518@1|root,arCOG00087@2157|Archaea,41SQR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR25158380_k127_3687121_13	1459636.NTE_01965	8.754e-101	340.0	COG1467@1|root,arCOG04110@2157|Archaea,41SCB@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
SRR25158380_k127_3687121_11	1459636.NTE_01964	1.035e-107	358.0	COG2219@1|root,arCOG03013@2157|Archaea,41SCD@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
SRR25158380_k127_3687121_15	1459636.NTE_01963	1.766e-90	306.0	COG0648@1|root,arCOG01894@2157|Archaea,41SDW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158380_k127_3687121_2	1459636.NTE_00981	1.296e-213	673.0	COG0423@1|root,arCOG00405@2157|Archaea,41S8S@651137|Thaumarchaeota	651137|Thaumarchaeota	J	synthetase (class II)	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158380_k127_3687121_14	1459636.NTE_00970	3.139e-92	306.0	COG2151@1|root,arCOG03838@1|root,arCOG01845@2157|Archaea,arCOG03838@2157|Archaea,41SHR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P,PqqD
SRR25158380_k127_3687121_8	1459636.NTE_00969	2.376e-138	448.0	COG0182@1|root,arCOG01123@2157|Archaea,41SF9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158380_k127_3687121_3	1459636.NTE_00968	2.174e-174	558.0	COG0677@1|root,arCOG00252@2157|Archaea	2157|Archaea	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158380_k127_3687121_6	1459636.NTE_02840	4.846e-145	467.0	COG1759@1|root,arCOG04346@2157|Archaea,41SBR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
SRR25158380_k127_3687121_20	1459636.NTE_00828	2.852e-57	203.0	arCOG04006@1|root,arCOG04006@2157|Archaea,41SKF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PBS lyase HEAT-like repeat	-	-	1.14.99.29	ko:K06072	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2
SRR25158380_k127_3687121_18	1459636.NTE_00827	1.861e-63	220.0	arCOG08712@1|root,arCOG08712@2157|Archaea,41SU6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3687121_29	1087481.AGFX01000022_gene2214	3.949e-15	80.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,4HDJQ@91061|Bacilli,26WHC@186822|Paenibacillaceae	91061|Bacilli	T	Cache 3/Cache 2 fusion domain	cckA	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158380_k127_3687121_26	1459636.NTE_01579	1.807e-33	134.0	COG1357@1|root,arCOG03124@2157|Archaea	2157|Archaea	M	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide,Pentapeptide_4
SRR25158380_k127_3687121_21	1459636.NTE_00643	1.332e-55	201.0	COG0503@1|root,arCOG00030@2157|Archaea,41SMR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158380_k127_3687121_10	1459636.NTE_00642	4.609e-108	355.0	COG0005@1|root,arCOG01327@2157|Archaea,41SDR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158380_k127_369464_1	1459636.NTE_01491	8.854e-09	62.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_369464_0	1459636.NTE_00005	4.444e-10	65.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_369464_2	1459636.NTE_00006	1.658e-08	59.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_369464_3	498848.TaqDRAFT_3369	3.769e-06	57.0	COG1525@1|root,COG1525@2|Bacteria,1WK0A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
SRR25158380_k127_370684_1	1459636.NTE_01844	1.046e-16	83.0	COG0026@1|root,arCOG01597@2157|Archaea,41SD9@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158380_k127_370684_0	1459636.NTE_03024	9.513e-26	113.0	COG1430@1|root,arCOG03116@2157|Archaea	2157|Archaea	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158380_k127_370923_0	1459636.NTE_03481	3.622e-102	348.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158380_k127_379179_0	521011.Mpal_1345	2.727e-63	228.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_379179_1	35128.Thaps261694	5.2e-16	91.0	COG1409@1|root,KOG1378@2759|Eukaryota,2XFBU@2836|Bacillariophyta	2836|Bacillariophyta	G	Iron/zinc purple acid phosphatase-like protein C	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C
SRR25158380_k127_380771_5	1459636.NTE_01001	3.932e-18	92.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_380771_2	523791.Kkor_0590	2.994e-78	273.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_380771_4	1459636.NTE_01046	7.732e-25	105.0	arCOG02240@1|root,arCOG02240@2157|Archaea	2157|Archaea	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase,Tautomerase_2
SRR25158380_k127_380771_8	1243664.CAVL020000019_gene3673	2.617e-05	55.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HCSH@91061|Bacilli,1ZCZY@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158380_k127_380771_3	1385935.N836_07015	6.178e-39	156.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158380_k127_380771_0	1459636.NTE_01052	1.726e-94	328.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_380771_6	1211844.CBLM010000035_gene3338	5.904e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,3VP3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_380771_1	1459636.NTE_00462	1.887e-88	300.0	COG0455@1|root,arCOG00589@2157|Archaea	2157|Archaea	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03496,ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
SRR25158380_k127_3823030_1	436308.Nmar_1786	1.568e-08	56.0	COG4221@1|root,arCOG01265@2157|Archaea,41S66@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_384019_3	378806.STAUR_7823	9.096e-43	169.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_384019_4	1459636.NTE_00881	2.637e-32	131.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_384019_7	1459636.NTE_00881	1.704e-21	101.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158380_k127_384019_8	1460635.JCM19038_1088	9.441e-08	61.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158380_k127_384019_0	635013.TherJR_1270	1.348e-105	360.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2606T@186807|Peptococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	noxE	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_384019_2	335283.Neut_1712	1.843e-48	186.0	COG3391@1|root,COG3391@2|Bacteria,1R78P@1224|Proteobacteria,2VJ7I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_384019_6	1162668.LFE_1240	1.537e-25	112.0	COG1765@1|root,COG1765@2|Bacteria	1162668.LFE_1240|-	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_384019_1	1048834.TC41_0139	1.174e-73	267.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158380_k127_384019_5	1459636.NTE_03027	2.12e-27	119.0	arCOG08805@1|root,arCOG08805@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_384529_0	523841.HFX_0791	4.943e-23	110.0	arCOG07550@1|root,arCOG07550@2157|Archaea,2XTFE@28890|Euryarchaeota,23U84@183963|Halobacteria	183963|Halobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF726,DUF900
SRR25158380_k127_385347_3	1121898.Q766_14970	2.133e-13	76.0	COG2323@1|root,COG2323@2|Bacteria,4NMYD@976|Bacteroidetes,1I1MG@117743|Flavobacteriia,2NZZ2@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158380_k127_385347_2	1459636.NTE_00054	3.63e-32	132.0	COG0328@1|root,arCOG02942@2157|Archaea	2157|Archaea	L	Ribonuclease	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158380_k127_385347_0	1459636.NTE_01927	1.6e-115	391.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158380_k127_385347_1	1459636.NTE_01493	3.744e-60	223.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_387105_2	1459636.NTE_03553	2.94e-224	699.0	COG0112@1|root,arCOG00070@2157|Archaea,41S7U@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158380_k127_387105_0	1459636.NTE_00079	0.0	1441.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
SRR25158380_k127_387105_5	1459636.NTE_00080	9.542e-108	353.0	COG1646@1|root,arCOG01085@2157|Archaea,41SH4@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
SRR25158380_k127_387105_15	1459636.NTE_00081	1.612e-05	52.0	arCOG08806@1|root,arCOG08806@2157|Archaea,41SUU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_387105_13	1459636.NTE_00082	5.896e-13	77.0	arCOG08041@1|root,arCOG08041@2157|Archaea,41SRT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
SRR25158380_k127_387105_3	1459636.NTE_00084	1.922e-174	555.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
SRR25158380_k127_387105_4	1459636.NTE_00085	8.456e-172	554.0	COG1311@1|root,arCOG04455@2157|Archaea,41T0D@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B
SRR25158380_k127_387105_10	1459636.NTE_00060	8.631e-46	170.0	arCOG01995@1|root,arCOG01995@2157|Archaea,41T3M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158380_k127_387105_7	1459636.NTE_00066	8.272e-80	273.0	COG2047@1|root,arCOG00348@2157|Archaea	2157|Archaea	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158380_k127_387105_6	1459636.NTE_00067	1.345e-105	347.0	COG2241@1|root,arCOG00650@2157|Archaea,41SGN@651137|Thaumarchaeota	651137|Thaumarchaeota	H	TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit	-	-	2.1.1.289	ko:K03399	ko00860,ko01100,map00860,map01100	-	R05813,R07775	RC00003,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158380_k127_387105_8	1459636.NTE_01446	6.405e-66	236.0	arCOG04054@1|root,arCOG04054@2157|Archaea,41SIQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_387105_12	1459636.NTE_02412	5.094e-17	83.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_387105_1	1459636.NTE_02371	2.235e-302	938.0	COG0365@1|root,arCOG01529@2157|Archaea,41S8Z@651137|Thaumarchaeota	651137|Thaumarchaeota	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158380_k127_387105_11	1459636.NTE_02337	5.315e-45	168.0	COG1430@1|root,arCOG03116@2157|Archaea,41SP3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158380_k127_387105_9	1459636.NTE_00070	5.924e-62	213.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_387105_14	436308.Nmar_0698	1.792e-06	50.0	COG1351@1|root,arCOG01884@2157|Archaea,41SF6@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158380_k127_3890840_6	203122.Sde_0034	3.145e-34	150.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1RBY7@1224|Proteobacteria,1SYWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Chondroitinase B	-	-	-	-	-	-	-	-	-	-	-	-	Chondroitinas_B,F5_F8_type_C
SRR25158380_k127_3890840_4	1459636.NTE_00031	2.621e-44	164.0	COG0864@1|root,arCOG01008@2157|Archaea,41SQM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
SRR25158380_k127_3890840_9	1158318.ATXC01000001_gene187	9.208e-17	88.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G3K2@200783|Aquificae	200783|Aquificae	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158380_k127_3890840_5	748449.Halha_2244	4.333e-44	172.0	COG0458@1|root,COG0458@2|Bacteria,1UIGF@1239|Firmicutes,25EMV@186801|Clostridia	186801|Clostridia	EF	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
SRR25158380_k127_3890840_0	1459636.NTE_02402	8.918e-90	312.0	COG1215@1|root,arCOG01389@2157|Archaea,41TAH@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glycos_transf_2
SRR25158380_k127_3890840_2	1459636.NTE_00033	5.518e-84	284.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158380_k127_3890840_1	1459636.NTE_00034	1.58e-84	290.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158380_k127_3890840_3	1459636.NTE_02430	1.891e-53	196.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_3890840_7	1459636.NTE_02864	3.824e-23	100.0	COG1996@1|root,arCOG04341@2157|Archaea,41SWH@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	-
SRR25158380_k127_3890840_8	1459636.NTE_00660	2.218e-20	91.0	arCOG08687@1|root,arCOG08687@2157|Archaea,41SVF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3895420_0	443255.SCLAV_1862	3.934e-13	79.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
SRR25158380_k127_3898666_4	1459636.NTE_03208	5.709e-12	66.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_3898666_3	1459636.NTE_01076	3.762e-42	163.0	COG1451@1|root,arCOG02625@2157|Archaea,41TA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158380_k127_3898666_0	1459636.NTE_00412	1.686e-117	382.0	COG2875@1|root,arCOG00645@2157|Archaea,41SE7@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158380_k127_3898666_1	1131266.ARWQ01000001_gene1298	8.015e-73	252.0	COG2243@1|root,arCOG00648@2157|Archaea,41SGJ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158380_k127_3898666_2	1459636.NTE_03264	2.555e-63	222.0	COG2242@1|root,arCOG00977@2157|Archaea,41SID@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7	cbiT	-	2.1.1.196	ko:K02191	ko00860,map00860	-	R05813,R07774	RC00003,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	Methyltransf_31
SRR25158380_k127_3899560_0	1198452.Jab_2c11280	6.745e-18	89.0	COG3631@1|root,COG3631@2|Bacteria,1RGEA@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158380_k127_3899560_1	1459636.NTE_02002	8.936e-18	87.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_3899560_2	511051.CSE_01460	0.0009135	49.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_2
SRR25158380_k127_3912108_1	1459636.NTE_00118	7.381e-29	120.0	COG2146@1|root,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158380_k127_396154_6	1459636.NTE_01147	2.32e-12	67.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_396154_1	1459636.NTE_02637	5.36e-66	237.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158380_k127_396154_3	436308.Nmar_0787	9.045e-36	141.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SS2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_396154_4	1120973.AQXL01000117_gene343	9.157e-14	77.0	2F6QX@1|root,33Z76@2|Bacteria,1VY7H@1239|Firmicutes,4HWZV@91061|Bacilli,27A4C@186823|Alicyclobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_396154_5	1192034.CAP_7835	1.919e-12	70.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,42V19@68525|delta/epsilon subdivisions,2WSZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_396154_7	1537917.JU82_10275	2.142e-09	59.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43DIT@68525|delta/epsilon subdivisions,2YTIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_396154_0	1459636.NTE_01150	3.123e-136	441.0	COG0346@1|root,arCOG03101@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158380_k127_396154_2	1459636.NTE_01151	6.363e-66	231.0	arCOG06256@1|root,arCOG06256@2157|Archaea	2157|Archaea	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158380_k127_4032344_0	580327.Tthe_2021	1.239e-123	405.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158380_k127_4039562_0	374847.Kcr_0237	7.898e-194	618.0	COG4670@1|root,arCOG01986@2157|Archaea	2157|Archaea	I	Acyl CoA acetate 3-ketoacid CoA transferase	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158380_k127_4039562_1	1120973.AQXL01000117_gene391	5.528e-65	243.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158380_k127_4039562_2	1459636.NTE_00890	2.022e-10	72.0	COG0517@1|root,arCOG00600@2157|Archaea	2157|Archaea	K	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_4047242_1	396595.TK90_2074	4.134e-30	126.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1T05M@1236|Gammaproteobacteria,1WXY2@135613|Chromatiales	135613|Chromatiales	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158380_k127_4050257_0	1459636.NTE_01493	2.34e-55	207.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_4050260_0	1459636.NTE_02077	6.554e-33	129.0	COG0426@1|root,arCOG00509@2157|Archaea	2157|Archaea	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_4050260_1	1459636.NTE_02077	3.997e-25	105.0	COG0426@1|root,arCOG00509@2157|Archaea	2157|Archaea	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_4050260_2	1459636.NTE_02077	8.734e-20	89.0	COG0426@1|root,arCOG00509@2157|Archaea	2157|Archaea	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_4050260_3	1385518.N798_03750	2.592e-09	67.0	29Y40@1|root,30JX3@2|Bacteria,2HY3H@201174|Actinobacteria,4FJMV@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_405976_0	1459636.NTE_00596	8.822e-20	94.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	2157|Archaea	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158380_k127_4079462_13	1459636.NTE_01934	4.03e-36	139.0	COG1436@1|root,arCOG04102@2157|Archaea,41T76@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
SRR25158380_k127_4079462_12	1459636.NTE_01942	6.706e-41	154.0	COG0484@1|root,arCOG02846@2157|Archaea,41T68@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
SRR25158380_k127_4079462_5	1459636.NTE_02261	1.377e-142	462.0	COG0457@1|root,arCOG03032@2157|Archaea,41SBD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
SRR25158380_k127_4079462_4	1459636.NTE_02257	1.256e-152	484.0	COG1635@1|root,arCOG00574@2157|Archaea,41SDJ@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
SRR25158380_k127_4079462_10	1229909.NSED_03445	5.969e-47	181.0	arCOG04668@1|root,arCOG04668@2157|Archaea,41SMD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4079462_3	1459636.NTE_02240	1.629e-153	491.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_4079462_2	1459636.NTE_02238	1.013e-165	526.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYM@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine synthase	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_4079462_14	1459636.NTE_02237	5.737e-30	121.0	COG0425@1|root,arCOG02062@2157|Archaea,41SU5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR25158380_k127_4079462_9	1459636.NTE_02235	7.025e-75	259.0	COG1478@1|root,arCOG02714@2157|Archaea,41T27@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158380_k127_4079462_7	1459636.NTE_02233	4.884e-96	319.0	COG0560@1|root,arCOG01158@2157|Archaea,41SHX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
SRR25158380_k127_4079462_8	1229909.NSED_03110	2.502e-93	320.0	arCOG01390@1|root,arCOG01390@2157|Archaea,41S7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158380_k127_4079462_11	436308.Nmar_1057	5.92e-46	175.0	COG2094@1|root,arCOG04295@2157|Archaea,41SME@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158380_k127_4079462_6	1459636.NTE_02003	1.921e-128	422.0	COG0750@1|root,arCOG04064@2157|Archaea,41SW5@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
SRR25158380_k127_4079462_0	1459636.NTE_02012	0.0	1020.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	2157|Archaea	S	RNA-metabolising metallo-beta-lactamase	epf2	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
SRR25158380_k127_4079462_1	1459636.NTE_02196	2.731e-190	611.0	COG1793@1|root,arCOG01347@2157|Archaea,41SCK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158380_k127_4079462_16	1459636.NTE_02195	3.968e-15	79.0	COG4901@1|root,arCOG04327@2157|Archaea,41SUF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	S25 ribosomal protein	-	-	-	ko:K02975	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S25
SRR25158380_k127_4184876_1	192952.MM_2642	1.445e-13	79.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUHN@28890|Euryarchaeota,2N9I0@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158380_k127_4184876_2	591019.Shell_0344	7.84e-07	53.0	COG0071@1|root,arCOG01833@2157|Archaea,2XQD6@28889|Crenarchaeota	28889|Crenarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158380_k127_4184876_0	1379698.RBG1_1C00001G0651	2.876e-33	134.0	COG2406@1|root,COG2406@2|Bacteria,2NS0E@2323|unclassified Bacteria	2|Bacteria	S	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158380_k127_4222004_4	1459636.NTE_02627	3.135e-15	78.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_4222004_5	253839.SSNG_00303	0.0001124	47.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_4222004_3	1459636.NTE_02626	9.349e-27	110.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_4222004_2	1459636.NTE_02626	7.647e-27	115.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_4222004_0	526218.Sterm_0782	1.569e-52	193.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,3787U@32066|Fusobacteria	32066|Fusobacteria	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
SRR25158380_k127_4222004_1	1278073.MYSTI_00289	4.113e-34	132.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
SRR25158380_k127_4238469_2	485913.Krac_7045	4.122e-44	166.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158380_k127_4238469_0	1459636.NTE_01395	2.523e-152	491.0	COG2132@1|root,arCOG03914@2157|Archaea,41S77@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_4238469_1	1459636.NTE_01396	1.321e-98	331.0	COG0428@1|root,arCOG00576@2157|Archaea,41S6R@651137|Thaumarchaeota	651137|Thaumarchaeota	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4245967_3	63737.Npun_F2216	3.539e-76	261.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria,1HQ1K@1161|Nostocales	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SRR25158380_k127_4245967_2	644966.Tmar_1413	1.721e-84	291.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WCYS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158380_k127_4245967_13	1121904.ARBP01000005_gene4462	2.535e-07	56.0	COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes	976|Bacteroidetes	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158380_k127_4245967_11	485913.Krac_11126	3.488e-26	112.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158380_k127_4245967_1	1379698.RBG1_1C00001G0911	2.34e-95	321.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	2.8.1.12,4.6.1.17	ko:K03635,ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	-	MOSC,MoCF_biosynth,MoaC
SRR25158380_k127_4245967_10	859653.HIMB5_00003360	2.059e-41	162.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158380_k127_4245967_7	403833.Pmob_0375	2.654e-55	210.0	COG0303@1|root,COG0303@2|Bacteria,2GCCX@200918|Thermotogae	200918|Thermotogae	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158380_k127_4245967_4	479434.Sthe_2181	1.091e-75	274.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158380_k127_4245967_9	1459636.NTE_01496	6.391e-51	200.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_4245967_8	1229909.NSED_02900	1.499e-53	192.0	COG0432@1|root,arCOG04214@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158380_k127_4245967_12	1459636.NTE_00669	1.813e-23	106.0	COG3685@1|root,arCOG11147@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158380_k127_4245967_0	1459636.NTE_00668	2.121e-167	535.0	COG1063@1|root,arCOG01459@2157|Archaea	2157|Archaea	C	Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a	fdh	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158380_k127_4245967_5	1459636.NTE_01148	1.305e-72	248.0	COG1225@1|root,arCOG00310@2157|Archaea	2157|Archaea	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158380_k127_4245967_6	1459636.NTE_01147	8.868e-63	221.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158380_k127_4248111_0	1459636.NTE_00434	3.849e-226	716.0	COG1796@1|root,arCOG00305@2157|Archaea	2157|Archaea	L	DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158380_k127_4248111_1	1459636.NTE_02848	1.088e-63	225.0	arCOG08811@1|root,arCOG08811@2157|Archaea,41T85@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4248111_2	1459636.NTE_02847	1.503e-38	161.0	arCOG06267@1|root,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	2157|Archaea	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158380_k127_4248111_3	1459636.NTE_02847	1.564e-25	115.0	arCOG06267@1|root,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	2157|Archaea	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158380_k127_4248111_4	1459636.NTE_02845	7.407e-15	76.0	COG3398@1|root,arCOG02611@2157|Archaea,41T7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158380_k127_4259877_5	211165.AJLN01000116_gene3317	1.237e-56	206.0	COG0412@1|root,COG0412@2|Bacteria,1G1CY@1117|Cyanobacteria,1JJI9@1189|Stigonemataceae	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158380_k127_4259877_2	1131266.ARWQ01000002_gene603	2.75e-75	263.0	arCOG01792@1|root,arCOG01792@2157|Archaea,41SFY@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158380_k127_4259877_0	1459636.NTE_03132	2.275e-138	448.0	COG0715@1|root,arCOG01803@2157|Archaea,41SG5@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158380_k127_4259877_4	1459636.NTE_01035	3.733e-61	223.0	COG0640@1|root,COG1809@1|root,arCOG00394@2157|Archaea,arCOG04896@2157|Archaea	2157|Archaea	K	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158380_k127_4259877_3	632335.Calkr_1166	4.752e-71	248.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,42G6K@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158380_k127_4259877_1	1459636.NTE_03130	1.931e-103	343.0	COG0600@1|root,arCOG00169@2157|Archaea,41SIT@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158380_k127_4264641_9	1459636.NTE_02193	1.098e-27	119.0	COG1758@1|root,arCOG01268@2157|Archaea,41ST9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	-	ko:K03014	ko00230,ko00240,ko01100,ko03020,ko04623,ko05016,ko05169,map00230,map00240,map01100,map03020,map04623,map05016,map05169	M00180,M00181,M00182	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158380_k127_4264641_4	1459636.NTE_02062	4.299e-60	214.0	COG1354@1|root,arCOG02610@2157|Archaea,41SMU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	-
SRR25158380_k127_4264641_3	1459636.NTE_02061	3.881e-65	227.0	COG1386@1|root,arCOG02613@2157|Archaea,41SIC@651137|Thaumarchaeota	651137|Thaumarchaeota	K	segregation and condensation protein	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158380_k127_4264641_5	1459636.NTE_02057	1.455e-43	162.0	COG2007@1|root,arCOG04154@2157|Archaea,41SP2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S8e	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
SRR25158380_k127_4264641_8	1459636.NTE_02055	1.722e-30	123.0	COG1400@1|root,arCOG01217@2157|Archaea,41SR5@651137|Thaumarchaeota	651137|Thaumarchaeota	U	SRP19 protein	-	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
SRR25158380_k127_4264641_10	1459636.NTE_02054	5.914e-15	78.0	COG3277@1|root,arCOG02466@2157|Archaea,41SVG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA-binding protein involved in rRNA processing	-	-	-	ko:K07569	-	-	-	-	ko00000,ko03009	-	-	-	Gar1
SRR25158380_k127_4264641_1	1459636.NTE_02053	9.393e-130	423.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158380_k127_4264641_6	1459636.NTE_01088	6.909e-32	126.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4264641_0	1459636.NTE_02657	3.65e-237	740.0	COG0644@1|root,arCOG00570@2157|Archaea,41SBB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4264641_2	436308.Nmar_1315	1.816e-77	266.0	COG2226@1|root,arCOG04348@2157|Archaea,41SGQ@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158380_k127_4264641_7	1459636.NTE_01424	2.67e-31	126.0	COG1146@1|root,arCOG08753@1|root,arCOG04548@2157|Archaea,arCOG08753@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_4266803_5	933262.AXAM01000164_gene2940	1.571e-22	111.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria,2MKYI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158380_k127_4266803_0	1459636.NTE_02247	1.465e-166	528.0	COG0535@1|root,arCOG00938@2157|Archaea,41SXS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158380_k127_4266803_2	1459636.NTE_00035	3.047e-49	182.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4266803_1	1459636.NTE_00935	2.05e-102	344.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158380_k127_4266803_3	1459636.NTE_02436	5.936e-42	166.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
SRR25158380_k127_4280598_1	5786.XP_003291163.1	1.891e-25	114.0	KOG0909@1|root,KOG0909@2759|Eukaryota,3XC3A@554915|Amoebozoa	554915|Amoebozoa	O	Transglutaminase/protease-like homologues	-	-	3.5.1.52	ko:K01456	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000	-	-	-	Lectin_legB,Transglut_core
SRR25158380_k127_4280598_0	1459636.NTE_02704	2.45e-27	112.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_428795_0	671143.DAMO_2372	1.289e-112	382.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_428795_1	485913.Krac_2322	1.276e-72	256.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_4327384_4	1229909.NSED_09545	2.993e-34	140.0	COG1746@1|root,arCOG04249@2157|Archaea,41S76@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
SRR25158380_k127_4327384_2	1229909.NSED_09550	7.577e-43	166.0	COG2112@1|root,arCOG01182@2157|Archaea,41SJV@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Ser thr protein kinase	-	-	-	ko:K07176	-	-	-	-	ko00000	-	-	-	RIO1
SRR25158380_k127_4327384_3	1459636.NTE_02408	4.646e-37	142.0	arCOG08080@1|root,arCOG08080@2157|Archaea,41SUA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4327384_1	436308.Nmar_0409	9.387e-130	429.0	COG0579@1|root,arCOG00754@2157|Archaea,41SXA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
SRR25158380_k127_4327384_0	1131266.ARWQ01000024_gene138	1.938e-194	621.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158380_k127_4327563_3	469382.Hbor_12790	1.064e-22	104.0	COG0529@1|root,arCOG01040@2157|Archaea,2XWW4@28890|Euryarchaeota,23V8B@183963|Halobacteria	183963|Halobacteria	P	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
SRR25158380_k127_4327563_1	1459636.NTE_03261	4.584e-94	316.0	COG1230@1|root,arCOG01477@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
SRR25158380_k127_4327563_7	1229909.NSED_06995	7.426e-05	52.0	COG4250@1|root,arCOG02910@2157|Archaea	2157|Archaea	T	Sensory domain in DIguanylate Cyclases and Two-component system	-	-	-	-	-	-	-	-	-	-	-	-	DICT
SRR25158380_k127_4327563_2	1459636.NTE_01727	3.353e-83	283.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158380_k127_4327563_5	1459636.NTE_02843	3.571e-17	89.0	arCOG08825@1|root,arCOG08825@2157|Archaea	1459636.NTE_02843|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4327563_0	1459636.NTE_02849	2.888e-190	626.0	COG4257@1|root,arCOG06267@1|root,arCOG03564@2157|Archaea,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	651137|Thaumarchaeota	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158380_k127_434148_0	1459636.NTE_01052	2.71e-51	191.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_434148_2	1121373.KB903654_gene1547	0.0002643	43.0	COG1145@1|root,32SB1@2|Bacteria,4NWKM@976|Bacteroidetes,47X5E@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158380_k127_434148_1	1459636.NTE_02515	3.855e-23	104.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158380_k127_4419378_9	1459636.NTE_01074	3.479e-11	70.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4419378_7	1459636.NTE_02664	6.83e-16	81.0	COG1409@1|root,arCOG06534@1|root,arCOG07781@1|root,arCOG09729@1|root,arCOG06534@2157|Archaea,arCOG07781@2157|Archaea,arCOG09729@2157|Archaea,arCOG11020@2157|Archaea	2157|Archaea	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,CHB_HEX_C_1,He_PIG,PKD,Polysacc_deac_1
SRR25158380_k127_4419378_3	1336243.JAEA01000005_gene1557	1.541e-29	127.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,1JTYX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2,PA14
SRR25158380_k127_4419378_8	1459636.NTE_02333	5.943e-12	71.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4419378_4	1079986.JH164837_gene5938	3.278e-24	104.0	COG4274@1|root,COG4274@2|Bacteria,2IN0N@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158380_k127_4419378_10	436308.Nmar_0709	8.977e-07	53.0	COG0778@1|root,arCOG00288@2157|Archaea,41T1J@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_4419378_6	304371.MCP_1711	2.119e-16	82.0	COG0778@1|root,arCOG00288@2157|Archaea,2XY3A@28890|Euryarchaeota,2NAXX@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_4419378_11	1123239.KB898623_gene1340	4.086e-05	55.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli	91061|Bacilli	S	acetoin utilization protein	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158380_k127_4419378_5	1459636.NTE_00325	5.742e-23	103.0	COG2149@1|root,arCOG05380@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158380_k127_4419378_1	436308.Nmar_1661	3.238e-43	162.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_4419378_2	1131266.ARWQ01000014_gene97	3.518e-40	150.0	arCOG06790@1|root,arCOG06790@2157|Archaea,41T7J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158380_k127_4426248_7	1459636.NTE_03136	2.419e-25	113.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4426248_9	1227500.C494_15163	5.121e-06	49.0	COG3039@1|root,arCOG02751@2157|Archaea,2XUAF@28890|Euryarchaeota,23UD8@183963|Halobacteria	183963|Halobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158380_k127_4426248_4	436308.Nmar_0250	1.681e-45	179.0	COG3221@1|root,arCOG01805@2157|Archaea	436308.Nmar_0250|-	P	ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	-
SRR25158380_k127_4426248_3	1459636.NTE_01496	4.715e-56	214.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_4426248_1	926549.KI421517_gene781	3.194e-87	293.0	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,47K2N@768503|Cytophagia	976|Bacteroidetes	C	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158380_k127_4426248_0	1459636.NTE_02626	3.893e-89	303.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_4426248_11	411483.FAEPRAA2165_03286	0.0006192	51.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158380_k127_4426248_6	765420.OSCT_0924	1.242e-31	139.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF
SRR25158380_k127_4426248_10	273057.SSO3023	0.0003059	46.0	arCOG02754@1|root,arCOG02754@2157|Archaea	2157|Archaea	S	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_5
SRR25158380_k127_4426248_8	1122217.KB899574_gene2039	8e-10	70.0	COG0726@1|root,COG0726@2|Bacteria,1UYYJ@1239|Firmicutes,4H3MV@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158380_k127_4426248_2	436308.Nmar_1680	7.271e-69	245.0	COG0697@1|root,arCOG00273@2157|Archaea,41T37@651137|Thaumarchaeota	651137|Thaumarchaeota	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158380_k127_4426884_5	436308.Nmar_0249	1.645e-11	68.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_4426884_1	436308.Nmar_0250	2.223e-45	179.0	COG3221@1|root,arCOG01805@2157|Archaea	436308.Nmar_0250|-	P	ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	-
SRR25158380_k127_4426884_4	1459636.NTE_02073	1.281e-12	69.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K11924	-	-	-	-	ko00000,ko03000	-	-	-	HTH_45
SRR25158380_k127_4426884_0	1459636.NTE_00038	9.813e-50	180.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158380_k127_4426884_2	1459636.NTE_00560	2.275e-29	121.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4426884_3	1459636.NTE_01072	8.557e-21	92.0	COG0667@1|root,arCOG01617@2157|Archaea,41SXK@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158380_k127_4442866_2	237368.SCABRO_03208	5.97e-75	264.0	COG4301@1|root,COG4301@2|Bacteria,2IXEH@203682|Planctomycetes	203682|Planctomycetes	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158380_k127_4442866_1	1131266.ARWQ01000011_gene107	7.034e-135	443.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR25158380_k127_4442866_3	1459636.NTE_01914	3.853e-68	241.0	COG0134@1|root,arCOG01088@2157|Archaea,41SN7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158380_k127_4442866_0	1459636.NTE_01913	7.558e-189	596.0	COG0133@1|root,arCOG01433@2157|Archaea,41S87@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_4442866_4	1459636.NTE_01912	1.446e-61	217.0	COG0159@1|root,arCOG01086@2157|Archaea,41SG0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158380_k127_4449753_1	521011.Mpal_1474	8.02e-78	271.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_4449753_2	391613.RTM1035_05490	2.574e-09	58.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,46NN6@74030|Roseovarius	28211|Alphaproteobacteria	Q	And related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158380_k127_4449753_0	1459636.NTE_02202	4.431e-97	327.0	COG1018@1|root,COG2146@1|root,arCOG02200@2157|Archaea,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	DAO,FAD_binding_6,NAD_binding_1,Rieske,Rieske_2
SRR25158380_k127_4465_0	1459636.NTE_00049	8.646e-30	123.0	COG2062@1|root,arCOG01992@2157|Archaea	2157|Archaea	T	TIGRFAM phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158380_k127_4465_3	1487953.JMKF01000041_gene3153	5.39e-11	71.0	28N7T@1|root,2ZBCE@2|Bacteria,1G50K@1117|Cyanobacteria,1H966@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4465_2	247490.KSU1_D0999	1.893e-19	101.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_4476720_0	525904.Tter_0425	6.126e-90	303.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158380_k127_4511628_6	1131266.ARWQ01000001_gene1117	4.397e-39	150.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158380_k127_4511628_3	373903.Hore_22980	8.16e-88	299.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,24G0B@186801|Clostridia	186801|Clostridia	P	-transport system	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158380_k127_4511628_4	403833.Pmob_1491	1.036e-83	286.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10109,ko:K10189,ko:K15771,ko:K17245,ko:K17316	ko02010,map02010	M00194,M00198,M00199,M00207,M00491,M00601,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.24,3.A.1.1.3,3.A.1.1.30,3.A.1.1.4,3.A.1.1.40	-	-	BPD_transp_1
SRR25158380_k127_4511628_1	1459636.NTE_01495	4.038e-157	507.0	COG1653@1|root,arCOG00151@2157|Archaea	2157|Archaea	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158380_k127_4511628_2	1365176.N186_07020	5.209e-108	361.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158380_k127_4511628_5	589924.Ferp_1638	2.326e-68	244.0	COG2152@1|root,arCOG04084@2157|Archaea,2XZSX@28890|Euryarchaeota	28890|Euryarchaeota	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158380_k127_4511628_0	1459636.NTE_01500	1.301e-167	535.0	COG0281@1|root,arCOG00853@2157|Archaea	2157|Archaea	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
SRR25158380_k127_4514411_0	1459636.NTE_03060	1.133e-117	389.0	COG1131@1|root,arCOG00196@2157|Archaea,41S73@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158380_k127_4514411_1	1459636.NTE_03061	1.979e-94	316.0	COG0842@1|root,arCOG01467@2157|Archaea,41SQQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158380_k127_454418_5	679926.Mpet_2032	1.158e-42	160.0	COG1742@1|root,arCOG07820@2157|Archaea,2XYGR@28890|Euryarchaeota,2NBC8@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Uncharacterised BCR, YnfA UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
SRR25158380_k127_454418_3	436308.Nmar_1681	1.027e-49	180.0	COG1742@1|root,arCOG07820@2157|Archaea,41TAS@651137|Thaumarchaeota	436308.Nmar_1681|-	S	Uncharacterised BCR, YnfA/UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	-
SRR25158380_k127_454418_1	1459636.NTE_00058	1.329e-74	257.0	COG0580@1|root,arCOG04431@2157|Archaea,41SJI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158380_k127_454418_4	1459636.NTE_00057	8.552e-49	178.0	COG0394@1|root,arCOG04425@2157|Archaea,41T49@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158380_k127_454418_0	1459636.NTE_00056	4.186e-80	274.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158380_k127_454418_2	1459636.NTE_00055	5.252e-52	186.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_4598608_0	1094980.Mpsy_0997	5.02e-54	213.0	COG0683@1|root,arCOG01021@2157|Archaea,2Y6Q1@28890|Euryarchaeota,2NAW8@224756|Methanomicrobia	224756|Methanomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158380_k127_460378_0	1459636.NTE_02925	9.076e-229	720.0	COG3569@1|root,arCOG08649@2157|Archaea,41SDH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA Topoisomerase I (eukaryota)	-	-	5.99.1.2	ko:K03163	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topo_C_assoc,Topoisom_I,Topoisom_I_N
SRR25158380_k127_460378_2	1459636.NTE_02502	1.26e-177	564.0	COG1060@1|root,arCOG00656@2157|Archaea,41SDT@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.77	ko:K11781	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_460378_5	1459636.NTE_02503	8.674e-130	426.0	COG1060@1|root,arCOG00657@2157|Archaea,41S95@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.77	ko:K11780	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158380_k127_460378_10	1459636.NTE_01639	1.792e-34	134.0	arCOG07440@1|root,arCOG07440@2157|Archaea,41STP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_460378_1	1459636.NTE_01640	1.564e-204	646.0	COG0008@1|root,arCOG00402@2157|Archaea,41SFI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158380_k127_460378_7	1459636.NTE_01641	1.138e-71	248.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41SMJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158380_k127_460378_6	1459636.NTE_00765	2.453e-83	287.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	2157|Archaea	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158380_k127_460378_3	1459636.NTE_00762	2.491e-155	496.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_460378_13	1459636.NTE_01573	1.766e-07	56.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_460378_8	436308.Nmar_0530	5.956e-68	238.0	COG2102@1|root,arCOG00035@2157|Archaea,41SHD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
SRR25158380_k127_460378_4	186497.PF1731	1.721e-130	430.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,24377@183968|Thermococci	183968|Thermococci	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158380_k127_460378_9	1459636.NTE_00777	3.004e-37	154.0	COG1258@1|root,arCOG01015@2157|Archaea,41SHC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	-	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	-
SRR25158380_k127_460378_11	1459636.NTE_00781	2.937e-26	111.0	arCOG08681@1|root,arCOG08681@2157|Archaea,41SH9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_460378_12	1131266.ARWQ01000005_gene842	3.79e-21	96.0	arCOG08681@1|root,arCOG08681@2157|Archaea,41SH9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4620470_1	1459636.NTE_02791	1.808e-39	150.0	COG1102@1|root,arCOG01037@2157|Archaea,41SKS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
SRR25158380_k127_4620470_0	1459636.NTE_02790	9.481e-134	433.0	COG0130@1|root,arCOG00987@2157|Archaea,41S8E@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	-	-	ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
SRR25158380_k127_4622082_0	247490.KSU1_C1274	1.208e-14	80.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_4622082_1	8090.ENSORLP00000018937	4.79e-06	55.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata,496SD@7742|Vertebrata,49XMF@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
SRR25158380_k127_464805_3	913865.DOT_2970	3.411e-12	72.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158380_k127_464805_4	1150474.JQJI01000006_gene839	3.793e-06	57.0	COG1388@1|root,COG4733@1|root,COG1388@2|Bacteria,COG4733@2|Bacteria,2GE91@200918|Thermotogae	2|Bacteria	M	Fibronectin type III domain	-	-	-	ko:K03933	-	-	-	-	ko00000	-	AA10,CBM73	-	Bac_DNA_binding,CHAP,fn3
SRR25158380_k127_464805_2	1459636.NTE_01088	1.75e-20	94.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_464805_0	436308.Nmar_1695	4.649e-118	388.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158380_k127_464805_1	1459636.NTE_00136	1.125e-55	205.0	COG1938@1|root,arCOG00347@2157|Archaea,41SSA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158380_k127_4654_14	1459636.NTE_01193	1.26e-66	230.0	COG0071@1|root,COG0705@1|root,arCOG01768@2157|Archaea,arCOG01833@2157|Archaea,41SKD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158380_k127_4654_20	1459636.NTE_01195	1.823e-31	124.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4654_10	1459636.NTE_01196	1.185e-107	354.0	COG4742@1|root,arCOG04362@2157|Archaea,41SGE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158380_k127_4654_3	1459636.NTE_02976	5.936e-194	613.0	COG0017@1|root,arCOG00407@2157|Archaea	2157|Archaea	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158380_k127_4654_24	1459636.NTE_03029	1.765e-13	71.0	arCOG08748@1|root,arCOG08748@2157|Archaea,41SV7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4654_18	1459636.NTE_00947	2.622e-46	172.0	arCOG08749@1|root,arCOG08749@2157|Archaea,41SRV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4654_21	1459636.NTE_00946	1.533e-19	91.0	COG1761@1|root,arCOG04111@2157|Archaea,41SV9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb3/Rpb11 dimerisation domain	-	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
SRR25158380_k127_4654_19	1459636.NTE_00945	2.469e-34	134.0	COG1594@1|root,arCOG00579@2157|Archaea,41SS3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	-	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	TFIIS_C
SRR25158380_k127_4654_9	1459636.NTE_00934	1.816e-115	376.0	COG0592@1|root,arCOG00488@2157|Archaea,41S6E@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
SRR25158380_k127_4654_4	1459636.NTE_00933	1.851e-183	584.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
SRR25158380_k127_4654_8	1459636.NTE_00916	1.688e-142	455.0	COG1010@1|root,arCOG00647@2157|Archaea,41S6W@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158380_k127_4654_6	1459636.NTE_01075	2.925e-153	490.0	COG0162@1|root,arCOG01886@2157|Archaea,41S8C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Tyrosine--tRNA ligase	-	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
SRR25158380_k127_4654_5	1459636.NTE_02034	2.584e-153	492.0	COG0045@1|root,arCOG01337@2157|Archaea,41S5M@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158380_k127_4654_7	1459636.NTE_02033	8.7e-148	472.0	COG0074@1|root,arCOG01339@2157|Archaea,41SEU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158380_k127_4654_15	436308.Nmar_0839	4.002e-64	229.0	COG2263@1|root,arCOG00910@2157|Archaea,41S85@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4654_13	1459636.NTE_03296	9.229e-76	273.0	COG0467@1|root,arCOG01171@2157|Archaea	2157|Archaea	T	Circadian clock protein KaiC	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATPase,Arf,Robl_LC7,zf-FCS
SRR25158380_k127_4654_16	1459636.NTE_03289	4.26e-55	196.0	COG1781@1|root,arCOG04229@2157|Archaea,41SJT@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
SRR25158380_k127_4654_23	436308.Nmar_1688	2.631e-17	85.0	COG0636@1|root,arCOG02455@2157|Archaea,41T6A@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158380_k127_4654_11	1459636.NTE_03277	6.997e-89	297.0	COG1394@1|root,arCOG04101@2157|Archaea,41T0N@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SRR25158380_k127_4654_1	1459636.NTE_03278	2.214e-256	795.0	COG1156@1|root,arCOG00865@2157|Archaea,41SPY@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158380_k127_4654_0	1229909.NSED_09005	4.114e-305	943.0	COG1155@1|root,arCOG00868@2157|Archaea,41SZU@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SRR25158380_k127_4654_17	1459636.NTE_03280	2.561e-54	197.0	COG1390@1|root,arCOG00869@2157|Archaea,41T4W@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
SRR25158380_k127_4654_12	1459636.NTE_03282	1.714e-80	272.0	COG0517@1|root,arCOG00606@2157|Archaea	2157|Archaea	I	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_4654_2	1459636.NTE_03283	2.756e-215	687.0	COG1293@1|root,arCOG01695@2157|Archaea,41SB0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SRR25158380_k127_4654_25	1459636.NTE_03265	6.677e-13	72.0	arCOG10415@1|root,arCOG10415@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4659615_0	927677.ALVU02000001_gene2461	3.876e-90	308.0	COG0596@1|root,COG0596@2|Bacteria,1G6JI@1117|Cyanobacteria,1H5B0@1142|Synechocystis	1117|Cyanobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158380_k127_4659615_3	35754.JNYJ01000020_gene250	1.164e-31	132.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4D9IZ@85008|Micromonosporales	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158380_k127_4659615_1	436308.Nmar_0008	2.458e-89	323.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158380_k127_4659615_4	1459636.NTE_02704	2.829e-22	97.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4659615_6	706587.Desti_4763	5.548e-13	78.0	COG3025@1|root,COG3025@2|Bacteria	2|Bacteria	S	triphosphatase activity	ygiF	-	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
SRR25158380_k127_4659615_7	1229909.NSED_00520	2.031e-07	60.0	arCOG11548@1|root,arCOG11548@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4659615_2	330214.NIDE3819	7.472e-73	259.0	COG2843@1|root,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158380_k127_4665195_0	1459636.NTE_01493	2.234e-50	192.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_4665195_1	1459636.NTE_01927	8.67e-50	187.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158380_k127_4740387_1	1459636.NTE_01962	3.281e-11	69.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4740387_0	436308.Nmar_1271	3.324e-34	142.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158380_k127_4772889_3	1459636.NTE_02554	2.599e-06	50.0	COG1143@1|root,arCOG01543@2157|Archaea,41SGW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4
SRR25158380_k127_4772889_1	1459636.NTE_01491	1.709e-24	107.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4772889_4	1540257.JQMW01000013_gene1255	3.433e-05	48.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,36F08@31979|Clostridiaceae	186801|Clostridia	T	response regulator	phoP	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158380_k127_4772889_2	436308.Nmar_1354	1.362e-16	84.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_4772889_0	1459636.NTE_01534	1.032e-109	367.0	COG0389@1|root,COG1801@1|root,arCOG04291@2157|Archaea,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota	2157|Archaea	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158380_k127_4779769_2	1229909.NSED_08245	3.997e-12	70.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4779769_3	1313421.JHBV01000155_gene784	9.127e-09	66.0	28MC2@1|root,2ZAQD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4779769_0	1267533.KB906733_gene3018	1.101e-29	129.0	COG0266@1|root,COG0266@2|Bacteria,3Y2WM@57723|Acidobacteria,2JIQF@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158380_k127_4779769_1	420324.KI912026_gene4978	3.019e-18	93.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HemolysinCabind,LTD
SRR25158380_k127_4780450_1	1459636.NTE_02626	3.985e-81	278.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158380_k127_4780450_0	1459636.NTE_01496	3.788e-140	466.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_4780450_2	1459636.NTE_00871	2.315e-68	242.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158380_k127_4780450_6	344747.PM8797T_30142	0.0004135	46.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158380_k127_4780450_5	1229909.NSED_01035	1.872e-05	47.0	COG5466@1|root,arCOG05278@2157|Archaea	2157|Archaea	S	small metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158380_k127_4786357_0	1459636.NTE_03129	3.215e-75	263.0	COG0412@1|root,arCOG01659@2157|Archaea,41T1E@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Chlorophyllase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158380_k127_4786357_1	1459636.NTE_03231	1.763e-26	109.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4786357_4	1444309.JAQG01000147_gene992	1.373e-07	60.0	2F6QX@1|root,33Z76@2|Bacteria,1VY7H@1239|Firmicutes,4HWZV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4789296_9	1459636.NTE_00236	1.329e-17	87.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4789296_2	391587.KAOT1_19772	1.085e-80	281.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158380_k127_4789296_4	1459636.NTE_00032	9.661e-74	259.0	COG0803@1|root,arCOG01005@2157|Archaea,41T29@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158380_k127_4789296_5	1463885.KL578392_gene2362	1.761e-46	181.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158380_k127_4789296_10	82996.sch_15700	8.836e-16	79.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,4043F@613|Serratia	1236|Gammaproteobacteria	S	ChaB	chaB	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
SRR25158380_k127_4789296_8	44251.PDUR_01110	1.753e-22	99.0	COG0596@1|root,COG0596@2|Bacteria,1USYC@1239|Firmicutes,4HBXD@91061|Bacilli,26VX0@186822|Paenibacillaceae	91061|Bacilli	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158380_k127_4789296_3	1459636.NTE_03260	2.082e-80	283.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4789296_6	1459636.NTE_00603	1.193e-25	111.0	arCOG08747@1|root,arCOG08747@2157|Archaea,41T48@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4789296_1	1459636.NTE_00766	6.258e-116	381.0	COG0598@1|root,arCOG02265@2157|Archaea,41SZC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158380_k127_4789296_11	436308.Nmar_1147	2.534e-12	68.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158380_k127_4789296_0	697281.Mahau_1243	8.69e-189	614.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,42EQF@68295|Thermoanaerobacterales	186801|Clostridia	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158380_k127_4789296_7	1279009.ADICEAN_00035	1.184e-22	104.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Malectin
SRR25158380_k127_4789556_0	1459636.NTE_00443	7.371e-158	535.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158380_k127_4789556_1	1346791.M529_15545	1.927e-11	77.0	COG0446@1|root,COG1752@1|root,COG0446@2|Bacteria,COG1752@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,2K12H@204457|Sphingomonadales	204457|Sphingomonadales	S	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3734,Patatin,Pyr_redox_2,Reductase_C
SRR25158380_k127_4793795_0	1459636.NTE_01128	1.95e-51	186.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158380_k127_4799584_3	1459636.NTE_01106	1.131e-82	285.0	COG0367@1|root,arCOG04741@1|root,arCOG00071@2157|Archaea,arCOG04741@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRR25158380_k127_4799584_4	1459636.NTE_01788	3.282e-78	267.0	COG5491@1|root,arCOG00452@2157|Archaea,41T30@651137|Thaumarchaeota	651137|Thaumarchaeota	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4799584_7	1459636.NTE_01789	1.315e-29	121.0	arCOG08722@1|root,arCOG08722@2157|Archaea,41SSI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4799584_5	1292035.H476_0728	3.904e-78	275.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,25SGT@186804|Peptostreptococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	bioF	-	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,BioW
SRR25158380_k127_4799584_1	1459636.NTE_01791	1.448e-145	468.0	COG0502@1|root,arCOG00658@2157|Archaea,41S9Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
SRR25158380_k127_4799584_2	1459636.NTE_01808	5.656e-91	303.0	COG1961@1|root,arCOG03162@2157|Archaea	2157|Archaea	L	resolvase	-	-	-	ko:K14060	-	-	-	-	ko00000	-	-	-	HTH_7,Recombinase,Resolvase
SRR25158380_k127_4799584_0	1459636.NTE_01809	1.477e-165	533.0	COG0161@1|root,arCOG00917@2157|Archaea,41S7K@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158380_k127_4799584_6	1459636.NTE_01810	9.57e-48	179.0	COG0132@1|root,arCOG00100@2157|Archaea,41SQX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR25158380_k127_4810_0	368408.Tpen_0197	9.115e-207	671.0	COG0474@1|root,arCOG01578@2157|Archaea,2XQ51@28889|Crenarchaeota	28889|Crenarchaeota	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158380_k127_4810_2	1459636.NTE_00055	3.324e-14	72.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_4810_1	313606.M23134_00658	3.486e-70	258.0	COG3243@1|root,COG3243@2|Bacteria,4P0GQ@976|Bacteroidetes,47TSY@768503|Cytophagia	976|Bacteroidetes	I	PHB de-polymerase C-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158380_k127_4811891_0	1041930.Mtc_1620	3.496e-256	811.0	COG2217@1|root,COG3350@1|root,arCOG01576@2157|Archaea,arCOG04507@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158380_k127_4811891_3	1459636.NTE_02515	2.371e-21	99.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158380_k127_4811891_2	1459636.NTE_01729	1.462e-39	153.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158380_k127_4811891_5	632245.CLP_2407	2.601e-16	81.0	COG0861@1|root,COG0861@2|Bacteria,1V1M1@1239|Firmicutes,248UB@186801|Clostridia,36E99@31979|Clostridiaceae	186801|Clostridia	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158380_k127_4811891_1	1459636.NTE_03510	5.704e-53	193.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158380_k127_4811891_4	248742.XP_005649230.1	8.606e-17	91.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158380_k127_4811960_0	913865.DOT_2970	1.247e-13	76.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158380_k127_4819135_4	1459636.NTE_00049	1.11e-06	51.0	COG2062@1|root,arCOG01992@2157|Archaea	2157|Archaea	T	TIGRFAM phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158380_k127_4819135_0	1459636.NTE_00050	1.745e-104	358.0	COG0248@1|root,arCOG05138@2157|Archaea	2157|Archaea	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158380_k127_4819135_1	1459636.NTE_00051	4.555e-99	328.0	COG0125@1|root,arCOG01891@2157|Archaea	2157|Archaea	F	thymidylate kinase	-	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158380_k127_4819135_2	1459636.NTE_00052	5.9e-98	325.0	COG0125@1|root,arCOG01891@2157|Archaea	1459636.NTE_00052|-	F	thymidylate kinase	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158380_k127_4819135_3	1459636.NTE_02269	1.483e-37	143.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158380_k127_4952699_0	644966.Tmar_1585	1.128e-22	101.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,24M30@186801|Clostridia,3WDMV@538999|Clostridiales incertae sedis	186801|Clostridia	C	Domain of Unknown Function (DUF326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158380_k127_4974318_3	102129.Lepto7375DRAFT_7767	1.144e-16	86.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158380_k127_4974318_0	1229909.NSED_03795	1.225e-91	319.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_4974318_1	1121430.JMLG01000002_gene1312	3.621e-47	178.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,2623X@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158380_k127_5111_36	1459636.NTE_01713	1.436e-20	92.0	COG0346@1|root,arCOG02708@2157|Archaea,41SU3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158380_k127_5111_38	1459636.NTE_02163	6.999e-09	68.0	arCOG08635@1|root,arCOG08635@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5111_33	1459636.NTE_02162	3.922e-25	104.0	COG2126@1|root,arCOG04126@2157|Archaea,41T9V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl37e	-	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
SRR25158380_k127_5111_27	1459636.NTE_02161	2.386e-33	129.0	COG1958@1|root,arCOG00998@2157|Archaea,41SU9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
SRR25158380_k127_5111_15	1459636.NTE_02160	1.185e-68	240.0	COG1402@1|root,arCOG04536@2157|Archaea,41SNC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158380_k127_5111_8	1459636.NTE_02159	1.277e-127	415.0	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
SRR25158380_k127_5111_4	1459636.NTE_01223	6.072e-184	586.0	COG1109@1|root,arCOG00767@2157|Archaea,41S74@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the phosphohexose mutase family	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158380_k127_5111_19	1459636.NTE_01204	3.615e-54	192.0	COG1358@1|root,arCOG01751@2157|Archaea,41SMS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	-	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
SRR25158380_k127_5111_28	1459636.NTE_01203	8.332e-30	119.0	COG2053@1|root,arCOG04314@2157|Archaea,41ST6@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	-	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
SRR25158380_k127_5111_29	1459636.NTE_01202	1.57e-29	118.0	COG2075@1|root,arCOG01950@2157|Archaea,41T7M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl24e	-	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
SRR25158380_k127_5111_18	1459636.NTE_01201	7.181e-56	197.0	COG0105@1|root,arCOG04313@2157|Archaea,41SN1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158380_k127_5111_1	1459636.NTE_01200	2.021e-282	878.0	COG0532@1|root,arCOG01560@2157|Archaea,41SBY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D4,IF-2
SRR25158380_k127_5111_21	1459636.NTE_01199	2.277e-47	172.0	COG0526@1|root,arCOG01972@2157|Archaea,41T6S@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158380_k127_5111_34	1459636.NTE_01604	5.335e-23	106.0	COG1371@1|root,arCOG04055@2157|Archaea,41SU0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158380_k127_5111_5	1459636.NTE_01603	5.553e-146	473.0	COG0124@1|root,arCOG00404@2157|Archaea,41S9T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	histidyl-tRNA synthetase	-	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158380_k127_5111_0	1459636.NTE_01594	4.797e-316	974.0	COG1053@1|root,arCOG00571@2157|Archaea,41SAM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	fumarate reductase flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158380_k127_5111_16	1459636.NTE_01593	1.211e-66	231.0	COG2009@1|root,arCOG02244@2157|Archaea,41SKZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158380_k127_5111_24	1459636.NTE_01592	2.461e-40	153.0	COG2142@1|root,arCOG04162@2157|Archaea,41SRA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158380_k127_5111_11	1459636.NTE_01591	3.071e-111	366.0	COG0479@1|root,arCOG00962@2157|Archaea,41SAW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158380_k127_5111_22	1459636.NTE_01588	3.87e-46	168.0	COG2151@1|root,arCOG01845@2157|Archaea,41SQV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158380_k127_5111_6	1459636.NTE_01585	7.158e-142	466.0	COG0165@1|root,arCOG01748@2157|Archaea,41S6A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158380_k127_5111_12	1459636.NTE_02312	2.479e-92	316.0	COG1817@1|root,arCOG01395@2157|Archaea,41S8D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158380_k127_5111_10	1459636.NTE_02313	1.815e-124	409.0	COG1250@1|root,arCOG00250@2157|Archaea	2157|Archaea	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158380_k127_5111_13	1459636.NTE_02309	1.366e-72	249.0	COG0110@1|root,arCOG01848@2157|Archaea,41SJ0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158380_k127_5111_31	1229909.NSED_01145	4.947e-27	114.0	COG2835@1|root,arCOG04124@2157|Archaea,41STB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
SRR25158380_k127_5111_9	1459636.NTE_02307	7.016e-126	411.0	COG0673@1|root,arCOG01622@2157|Archaea,41SZ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158380_k127_5111_7	1459636.NTE_02306	9.831e-131	423.0	COG0115@1|root,arCOG02297@2157|Archaea,41S5T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158380_k127_5111_17	1459636.NTE_02305	1.36e-64	227.0	COG1056@1|root,arCOG00972@2157|Archaea,41SHQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Nicotinamide-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_5111_25	1459636.NTE_02304	5.337e-40	151.0	COG1581@1|root,arCOG01753@2157|Archaea,41SQ4@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
SRR25158380_k127_5111_20	593117.TGAM_0530	1.144e-50	199.0	COG0467@1|root,arCOG01174@2157|Archaea,2XV95@28890|Euryarchaeota,243WZ@183968|Thermococci	183968|Thermococci	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158380_k127_5111_30	263820.PTO0494	4.073e-27	113.0	COG0636@1|root,arCOG02455@2157|Archaea,2Y1B9@28890|Euryarchaeota,242DV@183967|Thermoplasmata	183967|Thermoplasmata	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158380_k127_5111_39	186497.PF0179	7.398e-05	52.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,243A6@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
SRR25158380_k127_5111_14	273116.14324263	2.551e-71	254.0	COG1527@1|root,arCOG02459@2157|Archaea,2Y67I@28890|Euryarchaeota,24275@183967|Thermoplasmata	183967|Thermoplasmata	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SRR25158380_k127_5111_37	273116.14324264	5.213e-14	76.0	COG1436@1|root,arCOG04102@2157|Archaea,2Y5Y7@28890|Euryarchaeota,242ET@183967|Thermoplasmata	183967|Thermoplasmata	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
SRR25158380_k127_5111_2	273075.Ta0004	1.895e-230	726.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,241M5@183967|Thermoplasmata	183967|Thermoplasmata	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn,Intein_splicing
SRR25158380_k127_5111_3	273075.Ta0005	8.25e-219	686.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,241K0@183967|Thermoplasmata	183967|Thermoplasmata	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158380_k127_5111_23	273075.Ta0006	1.502e-42	164.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,241TN@183967|Thermoplasmata	183967|Thermoplasmata	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SRR25158380_k127_5111_26	1131266.ARWQ01000024_gene138	8.112e-40	153.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158380_k127_555094_1	247490.KSU1_D0999	4.229e-26	120.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_555094_2	247490.KSU1_D0999	8.045e-14	84.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158380_k127_555094_0	521011.Mpal_1345	1.389e-52	201.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158380_k127_56660_0	1459636.NTE_02040	6.542e-120	399.0	COG0351@1|root,COG1992@1|root,arCOG00020@2157|Archaea,arCOG00021@2157|Archaea,41SA1@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Phosphomethylpyrimidine kinase	-	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K21219	ko00730,ko01100,map00730,map01100	-	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
SRR25158380_k127_56660_1	1459636.NTE_02041	1.034e-106	349.0	COG1208@1|root,arCOG00663@2157|Archaea,41SGT@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158380_k127_56660_7	1459636.NTE_00631	2.023e-19	93.0	COG2412@1|root,arCOG04051@2157|Archaea,41SS6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
SRR25158380_k127_56660_5	1459636.NTE_00633	1.764e-55	199.0	COG1094@1|root,arCOG04150@2157|Archaea,41SNG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	K homology RNA-binding domain	-	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
SRR25158380_k127_56660_3	1459636.NTE_00635	3.744e-75	256.0	COG0163@1|root,arCOG01703@2157|Archaea,41SHU@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158380_k127_56660_2	1459636.NTE_00636	1.137e-89	304.0	COG0524@1|root,arCOG00014@2157|Archaea,41SX4@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158380_k127_56660_6	1229909.NSED_07785	7.654e-46	175.0	COG0284@1|root,arCOG00081@2157|Archaea,41SMN@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158380_k127_56660_4	1459636.NTE_00654	5.165e-61	218.0	arCOG08773@1|root,arCOG08773@2157|Archaea,41SNY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_580663_0	1459636.NTE_01573	2.391e-15	78.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_583594_0	1459636.NTE_00373	7.291e-97	332.0	COG2124@1|root,arCOG02814@2157|Archaea	2157|Archaea	C	cytochrome P450	cyp119	-	1.11.1.7,1.14.14.1	ko:K00493,ko:K21201	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158380_k127_583594_1	521011.Mpal_0423	2.241e-44	169.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
SRR25158380_k127_607410_8	1459636.NTE_01273	1.261e-15	79.0	arCOG03899@1|root,arCOG03899@2157|Archaea	2157|Archaea	L	endonuclease	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	HNH,HNH_3
SRR25158380_k127_607410_5	1459636.NTE_01696	7.778e-26	111.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158380_k127_607410_4	1459636.NTE_01698	2.126e-81	279.0	COG1712@1|root,arCOG00254@2157|Archaea,41SGA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
SRR25158380_k127_607410_0	1459636.NTE_01702	3.506e-158	503.0	COG0379@1|root,arCOG04459@2157|Archaea,41S6Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158380_k127_607410_7	1459636.NTE_01699	7.296e-19	87.0	COG4919@1|root,arCOG04293@2157|Archaea,41SVI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S30	-	-	-	ko:K02983	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121	-	-	-	Ribosomal_S30
SRR25158380_k127_607410_3	1459636.NTE_01703	7.412e-85	289.0	COG0157@1|root,arCOG01482@2157|Archaea,41SHI@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the catabolism of quinolinic acid (QA)	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158380_k127_607410_6	1459636.NTE_01704	8.763e-20	90.0	COG2093@1|root,arCOG04077@2157|Archaea,41SVE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
SRR25158380_k127_607410_2	1459636.NTE_01705	4.626e-96	317.0	COG1095@1|root,arCOG00675@2157|Archaea,41SGF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase	-	-	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
SRR25158380_k127_607410_1	1459636.NTE_01706	1.055e-98	325.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158380_k127_62066_10	935948.KE386494_gene559	3.78e-27	123.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158380_k127_62066_8	1459636.NTE_01281	2.257e-34	135.0	COG0526@1|root,arCOG01972@2157|Archaea,41SSR@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158380_k127_62066_13	1459636.NTE_03331	1.04e-13	76.0	COG0023@1|root,arCOG04223@2157|Archaea	2157|Archaea	J	Belongs to the SUI1 family	tif1a	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR25158380_k127_62066_14	1459636.NTE_03449	1.788e-10	62.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_62066_16	1459636.NTE_03449	0.0006651	43.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158380_k127_62066_11	1459636.NTE_03333	1.54e-16	89.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
SRR25158380_k127_62066_0	1459636.NTE_03330	5.653e-115	379.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	2157|Archaea	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158380_k127_62066_2	1459636.NTE_01998	8.301e-73	248.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158380_k127_62066_9	44689.DDB0232283	2.066e-30	136.0	COG1112@1|root,KOG1803@2759|Eukaryota,3XC2W@554915|Amoebozoa	554915|Amoebozoa	A	R3H domain	-	-	3.6.4.12,3.6.4.13	ko:K19036	-	-	-	-	ko00000,ko01000,ko03009,ko03012	-	-	-	AAA_12,R3H,zf-AN1
SRR25158380_k127_62066_7	1459636.NTE_01667	1.002e-37	145.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_62066_4	1459636.NTE_02269	1.201e-67	235.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158380_k127_62066_6	1459636.NTE_02711	3.164e-54	196.0	COG3224@1|root,arCOG08661@2157|Archaea	2157|Archaea	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
SRR25158380_k127_62066_15	679190.HMPREF0650_1560	0.0003273	52.0	COG2852@1|root,COG2852@2|Bacteria,4NUSE@976|Bacteroidetes,2FUH5@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158380_k127_62066_5	1459636.NTE_00549	8.225e-63	218.0	COG0229@1|root,arCOG02815@2157|Archaea	2157|Archaea	O	COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158380_k127_62066_1	1459636.NTE_00548	4.162e-88	293.0	COG0225@1|root,arCOG02816@2157|Archaea,41SMP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158380_k127_62066_3	1459636.NTE_00848	6.136e-70	242.0	arCOG03910@1|root,arCOG03910@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_639175_1	1123288.SOV_5c03890	1.646e-75	261.0	COG1099@1|root,COG1099@2|Bacteria,1UZM4@1239|Firmicutes	1239|Firmicutes	S	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
SRR25158380_k127_639175_0	1123288.SOV_5c03880	3.413e-86	293.0	COG1082@1|root,COG1082@2|Bacteria,1TSIG@1239|Firmicutes	1239|Firmicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158380_k127_639175_4	1229909.NSED_08245	8.118e-46	168.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_639175_3	1459636.NTE_02860	4.654e-65	228.0	COG2860@1|root,arCOG04641@2157|Archaea,41SIS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158380_k127_639175_6	1459636.NTE_02416	1.54e-39	155.0	COG0671@1|root,arCOG03056@2157|Archaea	2157|Archaea	I	PFAM phosphoesterase, PA-phosphatase related	sepP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158380_k127_639175_5	269797.Mbar_A0810	4.921e-44	179.0	COG3291@1|root,COG3391@1|root,arCOG03991@1|root,arCOG02508@2157|Archaea,arCOG02562@2157|Archaea,arCOG03991@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158380_k127_639175_2	1459636.NTE_01398	3.193e-74	261.0	arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_65311_1	1459636.NTE_01496	2.456e-47	189.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158380_k127_65311_2	1459636.NTE_03491	7.417e-14	74.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158380_k127_65311_0	1459636.NTE_01932	6.285e-94	323.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_668819_2	1129374.AJE_00290	7.818e-05	50.0	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,1S76Y@1236|Gammaproteobacteria,468B8@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158380_k127_668819_0	1459636.NTE_02332	2.69e-26	123.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_668819_1	913865.DOT_2970	9.449e-14	76.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158380_k127_672758_0	1459636.NTE_02143	1.261e-114	379.0	COG0381@1|root,arCOG01392@2157|Archaea,41SSN@651137|Thaumarchaeota	651137|Thaumarchaeota	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158380_k127_672758_8	208439.AJAP_12215	0.0001078	52.0	COG0500@1|root,COG0500@2|Bacteria,2IGIK@201174|Actinobacteria,4E33F@85010|Pseudonocardiales	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158380_k127_714473_2	1121289.JHVL01000020_gene826	0.0008146	43.0	COG0726@1|root,COG0726@2|Bacteria,1UZGG@1239|Firmicutes,249C9@186801|Clostridia,36FFF@31979|Clostridiaceae	186801|Clostridia	G	Polysaccharide deacetylase	pdaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158380_k127_714473_0	1459636.NTE_01493	1.646e-50	194.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158380_k127_73179_1	1459636.NTE_02973	2.799e-14	73.0	2DZ95@1|root,2N5MX@2157|Archaea,41T90@651137|Thaumarchaeota	1459636.NTE_02973|-	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	-
SRR25158380_k127_73179_0	1459636.NTE_01164	2.362e-30	123.0	arCOG00144@1|root,arCOG11894@1|root,arCOG00144@2157|Archaea,arCOG11894@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158380_k127_746480_9	483219.LILAB_32590	3.247e-10	64.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1MX4X@1224|Proteobacteria,43C05@68525|delta/epsilon subdivisions,2X7AX@28221|Deltaproteobacteria,2YWKH@29|Myxococcales	28221|Deltaproteobacteria	N	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRR25158380_k127_746480_7	459495.SPLC1_S041060	1.973e-15	86.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
SRR25158380_k127_746480_5	1459636.NTE_00902	1.594e-16	84.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR25158380_k127_746480_4	935836.JAEL01000032_gene3262	3.827e-28	120.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli,1ZJQU@1386|Bacillus	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158380_k127_746480_11	436308.Nmar_0408	1.749e-05	48.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158380_k127_746480_6	35128.Thaps261694	1.451e-15	89.0	COG1409@1|root,KOG1378@2759|Eukaryota,2XFBU@2836|Bacillariophyta	2836|Bacillariophyta	G	Iron/zinc purple acid phosphatase-like protein C	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C
SRR25158380_k127_746480_3	436308.Nmar_0408	3.577e-34	139.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158380_k127_746480_0	1459636.NTE_02192	1.264e-89	299.0	COG1249@1|root,arCOG01068@2157|Archaea	2157|Archaea	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_746480_2	1459636.NTE_02192	1.143e-56	203.0	COG1249@1|root,arCOG01068@2157|Archaea	2157|Archaea	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_746480_8	1459636.NTE_02192	4.509e-15	76.0	COG1249@1|root,arCOG01068@2157|Archaea	2157|Archaea	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158380_k127_746480_10	1459636.NTE_01491	6.268e-09	62.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_746480_1	224325.AF_1000	2.307e-66	234.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158380_k127_760237_8	1459636.NTE_02558	9.574e-35	134.0	COG0377@1|root,arCOG01554@2157|Archaea,41S6D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158380_k127_760237_5	1459636.NTE_02559	1.83e-59	207.0	COG0838@1|root,arCOG01557@2157|Archaea,41SMI@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158380_k127_760237_1	1459636.NTE_02579	2.538e-166	531.0	COG0644@1|root,arCOG00570@2157|Archaea,41S82@651137|Thaumarchaeota	651137|Thaumarchaeota	C	geranylgeranyl reductase	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_oxidored,Trp_halogenase
SRR25158380_k127_760237_6	1459636.NTE_02586	1.081e-46	173.0	COG1225@1|root,arCOG00310@2157|Archaea,41SN5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA antioxidant enzyme	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158380_k127_760237_9	1459636.NTE_02590	2.04e-34	133.0	COG1644@1|root,arCOG04244@2157|Archaea,41SPN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoN	-	2.7.7.6	ko:K03058	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_N
SRR25158380_k127_760237_0	1459636.NTE_02591	3.689e-173	552.0	COG0148@1|root,arCOG01169@2157|Archaea,41SE9@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158380_k127_760237_2	1459636.NTE_02594	2.349e-108	356.0	COG0052@1|root,arCOG04245@2157|Archaea,41SG7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158380_k127_760237_4	1229909.NSED_00885	1.827e-64	230.0	COG1355@1|root,arCOG01728@2157|Archaea,41S9D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR25158380_k127_760237_3	1459636.NTE_02597	8.124e-68	242.0	COG1577@1|root,arCOG01028@2157|Archaea,41SKC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158380_k127_760237_11	1229909.NSED_01515	6.093e-06	48.0	COG1608@1|root,arCOG00860@2157|Archaea,41SI4@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Amino acid kinase family	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158380_k127_76285_0	1459636.NTE_02605	1.01e-272	844.0	COG0464@1|root,arCOG01308@2157|Archaea,41SX8@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_76285_5	880073.Calab_3022	4.029e-143	468.0	COG1012@1|root,COG1012@2|Bacteria,2NQRG@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	gabD1	GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.gabD,iECUMN_1333.ECUMN_1793,iJN678.gabD	Aldedh
SRR25158380_k127_76285_3	1459636.NTE_02629	2.324e-194	618.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	2157|Archaea	E	TIGRFAM glutamine synthetase, type I	glnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_76285_8	1382356.JQMP01000003_gene1521	2.126e-18	88.0	arCOG11507@1|root,333W5@2|Bacteria,2G93V@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_76285_9	926562.Oweho_1108	1.358e-12	70.0	COG4095@1|root,COG4095@2|Bacteria,4NUQW@976|Bacteroidetes,1I54S@117743|Flavobacteriia	976|Bacteroidetes	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
SRR25158380_k127_76285_6	1459636.NTE_02476	2.296e-118	387.0	COG2086@1|root,arCOG00446@2157|Archaea,41SX2@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158380_k127_76285_4	1459636.NTE_02475	3.036e-158	509.0	COG2025@1|root,arCOG00448@2157|Archaea,41SZJ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158380_k127_76285_2	1131266.ARWQ01000002_gene512	1.206e-249	784.0	COG0644@1|root,COG2440@1|root,arCOG00570@2157|Archaea,arCOG01984@2157|Archaea,41SXJ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158380_k127_76285_7	1459636.NTE_03411	5.981e-83	277.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158380_k127_76285_1	1459636.NTE_01425	1.801e-263	824.0	COG0028@1|root,arCOG01999@2157|Archaea	2157|Archaea	C	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	Rubredoxin,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158380_k127_77655_1	1047013.AQSP01000097_gene1959	4.495e-33	142.0	COG1597@1|root,COG1597@2|Bacteria,2NPQE@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158380_k127_77655_0	1459636.NTE_02785	3.758e-158	509.0	COG0477@1|root,arCOG00132@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158380_k127_792324_3	1459636.NTE_03025	1.049e-35	139.0	COG0060@1|root,arCOG00807@2157|Archaea,41SFF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158380_k127_792324_2	1459636.NTE_02127	9.799e-72	253.0	COG2047@1|root,arCOG00348@2157|Archaea	2157|Archaea	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158380_k127_792324_0	436308.Nmar_0691	2.644e-90	307.0	COG0063@1|root,arCOG00018@2157|Archaea,41S8I@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
SRR25158380_k127_792324_1	1459636.NTE_03023	8.903e-85	301.0	COG1378@1|root,arCOG02038@2157|Archaea	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
SRR25158380_k127_792324_4	1459636.NTE_03022	2.107e-33	139.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
SRR25158380_k127_792324_5	1459636.NTE_01850	1.677e-26	110.0	COG1028@1|root,arCOG01259@2157|Archaea,41S7V@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_831117_2	489825.LYNGBM3L_16910	3.111e-08	57.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158380_k127_831117_0	1459636.NTE_01104	7.817e-94	313.0	COG1136@1|root,arCOG00922@2157|Archaea,41T2R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
SRR25158380_k127_831117_1	1459636.NTE_01103	6.979e-25	115.0	COG1361@1|root,arCOG02080@2157|Archaea,41T6N@651137|Thaumarchaeota	651137|Thaumarchaeota	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_9006_1	1459636.NTE_02630	3.381e-67	231.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158380_k127_9006_0	1229909.NSED_09490	3.37e-153	499.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158380_k127_916991_4	1459636.NTE_00401	7.293e-84	286.0	COG1794@1|root,arCOG02005@2157|Archaea,41SM4@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158380_k127_916991_0	1459636.NTE_02380	4.934e-285	891.0	COG0145@1|root,arCOG01511@2157|Archaea,41SZ7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158380_k127_916991_5	1459636.NTE_01392	2.541e-81	280.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
SRR25158380_k127_916991_3	1459636.NTE_01391	1.266e-107	357.0	COG1234@1|root,arCOG00501@2157|Archaea,41SF7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158380_k127_916991_7	1487953.JMKF01000017_gene2547	4.077e-40	152.0	COG0599@1|root,COG0599@2|Bacteria,1G6DQ@1117|Cyanobacteria	1117|Cyanobacteria	S	gamma-carboxymuconolactone decarboxylase subunit	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158380_k127_916991_6	1459636.NTE_01298	8.691e-74	256.0	COG0500@1|root,arCOG01631@2157|Archaea,41SJC@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DOT1
SRR25158380_k127_916991_1	1131266.ARWQ01000028_gene1022	2.55e-226	712.0	COG1866@1|root,arCOG06073@2157|Archaea,41SE5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158380_k127_916991_2	1459636.NTE_00430	2.159e-114	373.0	COG4221@1|root,arCOG01265@2157|Archaea,41S66@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158380_k127_917996_0	1229909.NSED_05590	1.054e-16	87.0	arCOG03622@1|root,arCOG03622@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_917996_1	1229909.NSED_05590	7.226e-09	61.0	arCOG03622@1|root,arCOG03622@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_926147_10	1459636.NTE_01106	0.0002263	45.0	COG0367@1|root,arCOG04741@1|root,arCOG00071@2157|Archaea,arCOG04741@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRR25158380_k127_926147_6	1459636.NTE_01786	8.519e-32	126.0	arCOG08697@1|root,arCOG08697@2157|Archaea,41SUN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_926147_0	1459636.NTE_01785	2.105e-226	707.0	COG0498@1|root,arCOG01434@2157|Archaea,41S5N@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158380_k127_926147_1	1459636.NTE_01784	3.053e-169	545.0	COG0147@1|root,arCOG02014@2157|Archaea,41S8W@651137|Thaumarchaeota	651137|Thaumarchaeota	E	component I	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158380_k127_926147_7	1459636.NTE_00966	1.968e-27	112.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_926147_8	1459636.NTE_01697	8.118e-22	97.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158380_k127_926147_5	748449.Halha_0139	1.765e-38	155.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WAXE@53433|Halanaerobiales	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158380_k127_926147_2	1459636.NTE_01981	7.737e-88	307.0	COG2379@1|root,arCOG04170@2157|Archaea,41SJF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158380_k127_926147_4	1459636.NTE_01975	5.169e-45	166.0	COG4911@1|root,arCOG05495@2157|Archaea,41SNJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158380_k127_926147_3	1459636.NTE_01973	4.522e-64	225.0	COG1575@1|root,arCOG00480@2157|Archaea,41S8H@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158380_k127_940745_1	1459636.NTE_00585	4.881e-25	108.0	arCOG07802@1|root,arCOG07802@2157|Archaea	2157|Archaea	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255,F420H2_quin_red
SRR25158380_k127_940745_0	927677.ALVU02000001_gene1822	8.52e-147	473.0	COG1064@1|root,COG1064@2|Bacteria,1G0B9@1117|Cyanobacteria,1H5JJ@1142|Synechocystis	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158380_k127_968640_2	1459636.NTE_03208	4.441e-17	83.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158380_k127_968640_0	1459636.NTE_03097	4.259e-151	491.0	arCOG03664@1|root,arCOG03664@2157|Archaea	2157|Archaea	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3
SRR25158380_k127_968640_1	1459636.NTE_00433	1.236e-38	150.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_972763_0	1459636.NTE_01295	1.965e-129	424.0	COG1415@1|root,arCOG04253@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
SRR25158380_k127_972763_2	1459636.NTE_02310	6.202e-98	329.0	COG1052@1|root,arCOG01755@2157|Archaea,41T1D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158380_k127_972763_5	1131266.ARWQ01000012_gene1609	8.01e-17	83.0	arCOG08666@1|root,arCOG08666@2157|Archaea,41SVR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_972763_7	1459636.NTE_01643	1.341e-12	68.0	arCOG10403@1|root,arCOG10403@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_972763_4	1459636.NTE_02286	2.064e-28	117.0	arCOG08688@1|root,arCOG08688@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_972763_3	1459636.NTE_01707	1.259e-39	153.0	COG1909@1|root,arCOG04076@2157|Archaea,41SNQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
SRR25158380_k127_972763_1	1459636.NTE_01706	4.126e-98	324.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158380_k127_986263_2	1459636.NTE_00423	7.063e-45	174.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41SS8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158380_k127_986263_1	436308.Nmar_0626	4.737e-99	332.0	COG0391@1|root,arCOG04395@2157|Archaea,41SCH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158380_k127_986263_3	1459636.NTE_01464	3.842e-35	142.0	COG1920@1|root,arCOG04472@2157|Archaea,41SPV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Guanylyl transferase CofC like	-	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158380_k127_986263_0	1459636.NTE_03106	3.845e-194	610.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
## 2083 queries scanned
## Total time (seconds): 2.6287930011749268
## Rate: 792.38 q/s