## Thu Feb 19 04:08:48 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158390_bin.19.fa -m mmseqs --output SRR25158390_bin.19 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158390_bin.19 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158390_k127_1001004_9	58123.JOFJ01000002_gene2365	1.15e-16	82.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4EHEX@85012|Streptosporangiales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158390_k127_1001004_1	1146883.BLASA_0347	1.639e-154	509.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4ERU6@85013|Frankiales	201174|Actinobacteria	GM	Polysaccharide biosynthesis protein	capD	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158390_k127_1001004_8	1348663.KCH_16800	4.363e-39	166.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2GJ1Y@201174|Actinobacteria,2M40M@2063|Kitasatospora	201174|Actinobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,Wzz
SRR25158390_k127_1001004_2	1348663.KCH_16860	5.749e-119	403.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,2M4SG@2063|Kitasatospora	201174|Actinobacteria	E	DegT DnrJ EryC1 StrS aminotransferase family	eryCIV	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158390_k127_1001004_4	383372.Rcas_3084	1.252e-92	331.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158390_k127_1001004_0	656024.FsymDg_1692	5.188e-161	519.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4ERD8@85013|Frankiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158390_k127_1001004_5	1146883.BLASA_0339	4.415e-91	317.0	28IEF@1|root,2Z8GG@2|Bacteria,2I8UG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1001004_3	67352.JODS01000028_gene2344	1.232e-106	366.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1001004_6	1123320.KB889607_gene9511	5.375e-79	274.0	COG0726@1|root,COG0726@2|Bacteria,2I8IQ@201174|Actinobacteria	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158390_k127_1001004_11	1283287.KB822577_gene3221	8.007e-05	55.0	COG4424@1|root,COG4424@2|Bacteria,2GMCB@201174|Actinobacteria,4DPB7@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158390_k127_1001004_7	452652.KSE_16420	1.049e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria,2M23E@2063|Kitasatospora	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1036971_5	1229780.BN381_170040	3.642e-60	218.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,3UW69@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158390_k127_1036971_8	1229780.BN381_170039	8.258e-40	156.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,3UWX1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Zn-ribbon protein, possibly nucleic acid-binding	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158390_k127_1036971_9	1313172.YM304_18970	5.128e-34	136.0	2C2HI@1|root,345RC@2|Bacteria,2H8AE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1036971_6	1120948.KB903244_gene2840	7.568e-59	213.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_1036971_3	1382306.JNIM01000001_gene876	4.08e-69	245.0	COG0384@1|root,COG0384@2|Bacteria,2G7RE@200795|Chloroflexi	200795|Chloroflexi	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158390_k127_1036971_4	1089545.KB913037_gene7246	2.075e-64	227.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4E046@85010|Pseudonocardiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158390_k127_1036971_0	1157943.KB892705_gene217	0.0	1129.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,232MQ@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.8	ko:K01537,ko:K12953	-	-	-	-	ko00000,ko01000	3.A.3,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_1036971_1	35754.JNYJ01000011_gene737	1.828e-98	336.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria,4DIGE@85008|Micromonosporales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1036971_7	448385.sce7002	2.103e-47	187.0	COG3173@1|root,COG3173@2|Bacteria,1P7JU@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1036971_10	525368.HMPREF0591_0961	4.514e-22	110.0	COG3688@1|root,COG3688@2|Bacteria,2HS1T@201174|Actinobacteria,23A4M@1762|Mycobacteriaceae	201174|Actinobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158390_k127_1036971_2	926560.KE387023_gene1198	7.059e-83	287.0	COG1609@1|root,COG1609@2|Bacteria,1WKYB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_1036971_11	1229780.BN381_800004	1.702e-12	73.0	2DDQ5@1|root,2ZIVU@2|Bacteria,2HDNV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1089360_7	146922.JOFU01000062_gene89	2.075e-59	215.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_1089360_1	1394178.AWOO02000087_gene942	8.186e-128	416.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4EPS2@85012|Streptosporangiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_1089360_8	501479.ACNW01000097_gene1078	4.587e-59	228.0	COG0463@1|root,COG0463@2|Bacteria,1NA50@1224|Proteobacteria,2UG62@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1089360_10	395495.Lcho_1381	1.809e-25	121.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria,1KP9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
SRR25158390_k127_1089360_9	56110.Oscil6304_1709	3.118e-51	204.0	COG2244@1|root,COG2244@2|Bacteria,1G3GP@1117|Cyanobacteria,1HAX2@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158390_k127_1089360_3	1194165.CAJF01000018_gene3603	5.666e-93	323.0	COG0438@1|root,COG0438@2|Bacteria,2GZMP@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158390_k127_1089360_4	326424.FRAAL6245	1.265e-87	298.0	COG4221@1|root,COG4221@2|Bacteria,2GKK7@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1089360_2	1464048.JNZS01000033_gene2794	1.713e-108	370.0	COG1075@1|root,COG1075@2|Bacteria,2HXFM@201174|Actinobacteria,4DI5G@85008|Micromonosporales	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRR25158390_k127_1089360_0	710696.Intca_0367	2.494e-147	482.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FGKI@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_1089360_11	511.JT27_05265	8.927e-20	97.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,3T45R@506|Alcaligenaceae	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_1089360_6	1463901.JOIY01000057_gene4691	1.584e-68	239.0	COG0693@1|root,COG0693@2|Bacteria,2H6FV@201174|Actinobacteria	201174|Actinobacteria	S	ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158390_k127_1089360_5	1380346.JNIH01000006_gene3399	7.43e-81	279.0	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158390_k127_1108211_11	1313172.YM304_24220	5.835e-71	252.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CN8K@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158390_k127_1108211_6	525909.Afer_1266	1.987e-109	358.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158390_k127_1108211_1	1380356.JNIK01000017_gene2900	1.237e-196	654.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158390_k127_1108211_0	1380354.JIAN01000009_gene3733	2.152e-246	801.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158390_k127_1108211_4	1108045.GORHZ_087_00210	3.396e-122	431.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4GCNF@85026|Gordoniaceae	201174|Actinobacteria	KL	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158390_k127_1108211_5	1313172.YM304_24100	2.327e-114	389.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CN3C@84992|Acidimicrobiia	84992|Acidimicrobiia	J	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158390_k127_1108211_14	1173020.Cha6605_4447	1.131e-27	131.0	COG1357@1|root,COG1357@2|Bacteria,1G8T3@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158390_k127_1108211_12	1229780.BN381_80285	2.552e-70	261.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,3UWZJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_1108211_10	1229780.BN381_80286	2.491e-75	273.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,3UWVZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_1108211_2	1229780.BN381_80287	1.976e-166	536.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,3UW7X@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158390_k127_1108211_18	521096.Tpau_3274	4.998e-08	64.0	COG3745@1|root,COG3745@2|Bacteria,2IT93@201174|Actinobacteria	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
SRR25158390_k127_1108211_15	1121877.JQKF01000022_gene2279	1.782e-17	84.0	2A7D0@1|root,30WA0@2|Bacteria,2HH43@201174|Actinobacteria,4CP42@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_1108211_9	1245475.ANAE01000161_gene845	3.336e-78	269.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4EQ04@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1108211_3	1229780.BN381_330095	1.518e-134	437.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,3UWEM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158390_k127_1108211_13	1313172.YM304_23950	9.317e-40	158.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CN8G@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158390_k127_1108211_8	1121877.JQKF01000022_gene2275	8.77e-94	333.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CP58@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_1108211_20	4529.ORUFI01G30810.1	2.948e-05	57.0	KOG0198@1|root,KOG0198@2759|Eukaryota,384CR@33090|Viridiplantae,3GSC8@35493|Streptophyta,3KPGI@4447|Liliopsida,3ICXC@38820|Poales	35493|Streptophyta	T	Belongs to the protein kinase superfamily	-	-	-	ko:K20716	ko04016,map04016	-	-	-	ko00000,ko00001,ko01001	-	-	-	Pkinase
SRR25158390_k127_1108211_21	1123322.KB904684_gene4797	0.0005554	51.0	COG1652@1|root,COG1652@2|Bacteria,2GMHG@201174|Actinobacteria	201174|Actinobacteria	M	Transglycosylase-like domain	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
SRR25158390_k127_1152563_9	502025.Hoch_4785	3.237e-06	60.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YV6N@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158390_k127_1152563_3	882083.SacmaDRAFT_1194	2.693e-112	385.0	COG1215@1|root,COG1215@2|Bacteria,2I4CF@201174|Actinobacteria,4EFEH@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1152563_5	1229780.BN381_250061	8.404e-73	267.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_1152563_4	656024.FsymDg_2777	9.581e-75	259.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4ESNU@85013|Frankiales	201174|Actinobacteria	S	PFAM Creatininase	mftE	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158390_k127_1152563_6	656024.FsymDg_2650	7.501e-48	186.0	COG2086@1|root,COG2086@2|Bacteria,2GSWB@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158390_k127_1152563_7	298654.FraEuI1c_4678	4.53e-46	181.0	COG2440@1|root,COG2440@2|Bacteria,2IQVY@201174|Actinobacteria	201174|Actinobacteria	C	electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ETF_QO,Fer4_9
SRR25158390_k127_1152563_2	1229780.BN381_250065	3.75e-180	574.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,FAD_oxidored,Pyr_redox_2
SRR25158390_k127_1152563_8	1463821.JOGR01000013_gene3146	1.75e-23	113.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4EXSZ@85014|Glycomycetales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158390_k127_1152563_0	1229780.BN381_250079	2.095e-307	955.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,3UWJK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	FAD_oxidored,Oxidored_FMN,Pyr_redox_2
SRR25158390_k127_1152563_1	1229780.BN381_250080	2.404e-208	665.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,3UWJK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158390_k127_1172528_5	1160137.KB907307_gene2996	2.742e-58	205.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4G2MT@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1172528_3	1894.JOER01000002_gene3502	1.216e-89	302.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_1172528_0	58123.JOFJ01000013_gene4952	5.452e-219	690.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4EIDS@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_1172528_9	675635.Psed_6151	7.997e-35	144.0	COG2912@1|root,COG2912@2|Bacteria,2GMER@201174|Actinobacteria,4EARR@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158390_k127_1172528_1	1313172.YM304_25510	2.709e-164	527.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CNFE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1172528_7	1313172.YM304_20180	3.112e-43	164.0	COG0406@1|root,COG0406@2|Bacteria,2GM22@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_1172528_8	561175.KB894098_gene5178	1.634e-39	151.0	COG0346@1|root,COG0346@2|Bacteria,2IHZH@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1172528_2	1313172.YM304_20190	6.001e-127	421.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CMXD@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158390_k127_1172528_10	1283283.ATXA01000010_gene4499	1.18e-33	141.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_1172528_4	1229780.BN381_50095	7.114e-88	304.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_1172528_6	1313172.YM304_20220	1.068e-44	170.0	2DMMI@1|root,32SFN@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
SRR25158390_k127_1172528_11	103733.JNYO01000003_gene8149	3.772e-24	117.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM,Methyltransf_19
SRR25158390_k127_1172528_12	45351.EDO30436	1.341e-10	69.0	2DY4I@1|root,2S6TY@2759|Eukaryota,3A8V3@33154|Opisthokonta,3C26E@33208|Metazoa	33208|Metazoa	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
SRR25158390_k127_1176533_7	1121877.JQKF01000001_gene1361	7.177e-78	274.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4CN35@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1176533_2	1229780.BN381_10190	4.593e-116	380.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_1176533_0	867845.KI911784_gene1522	9.001e-173	547.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_1176533_5	1313172.YM304_28610	3.557e-95	334.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CN0F@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158390_k127_1176533_6	1229780.BN381_10186	4.94e-85	288.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,3UXCJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158390_k127_1176533_4	1077144.AGFF01000007_gene1799	1.55e-103	345.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158390_k127_1176533_3	1229780.BN381_10183	7.113e-116	381.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,3UXFW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	JM	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158390_k127_1176533_8	1313172.YM304_28640	3.003e-22	107.0	2968S@1|root,2ZTIT@2|Bacteria,2HEBZ@201174|Actinobacteria,4CNCH@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1176533_1	1229780.BN381_10181	8.966e-146	474.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcaI	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
SRR25158390_k127_1185524_1	526225.Gobs_4444	4.424e-116	392.0	COG5305@1|root,COG5305@2|Bacteria,2HTG8@201174|Actinobacteria,4ESH8@85013|Frankiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158390_k127_1185524_0	656024.FsymDg_1995	8.503e-217	684.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158390_k127_1185524_2	1229780.BN381_150001	1.183e-78	285.0	COG1807@1|root,COG1807@2|Bacteria,2IITJ@201174|Actinobacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158390_k127_1185524_3	1229780.BN381_310086	8.404e-45	181.0	COG1807@1|root,COG1807@2|Bacteria,2H9UZ@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1185524_5	219305.MCAG_01401	1.689e-29	136.0	COG0500@1|root,COG2226@2|Bacteria,2HX1M@201174|Actinobacteria,4DIQG@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1185524_4	886293.Sinac_4732	2.613e-35	154.0	COG1215@1|root,COG1215@2|Bacteria,2J0E2@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1201106_29	928724.SacglDRAFT_00071	1.991e-80	282.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4DYRP@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158390_k127_1201106_38	1380347.JNII01000008_gene4221	2.577e-58	217.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4ESKP@85013|Frankiales	201174|Actinobacteria	O	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158390_k127_1201106_44	1298863.AUEP01000003_gene2799	4.591e-54	194.0	COG1853@1|root,COG1853@2|Bacteria,2IICG@201174|Actinobacteria	201174|Actinobacteria	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158390_k127_1201106_49	585531.HMPREF0063_11667	2.002e-46	179.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4DQII@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158390_k127_1201106_54	1242864.D187_008306	3.23e-37	161.0	COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158390_k127_1201106_10	926550.CLDAP_08960	1.214e-141	462.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158390_k127_1201106_17	1380393.JHVP01000005_gene3634	3.046e-107	378.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4EU4Q@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158390_k127_1201106_12	1128427.KB904821_gene500	7.044e-132	428.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1201106_40	1313172.YM304_42510	3.243e-57	209.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1201106_67	287986.DV20_10030	7.834e-19	97.0	COG3832@1|root,COG3832@2|Bacteria,2IKZ7@201174|Actinobacteria,4E4I0@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_1201106_4	1380354.JIAN01000011_gene3235	1.492e-180	583.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4F0DF@85016|Cellulomonadaceae	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158390_k127_1201106_5	28444.JODQ01000008_gene1111	1.445e-178	567.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4EGS8@85012|Streptosporangiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-associated	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_1201106_15	1033730.CAHG01000002_gene2884	9.841e-114	376.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DN36@85009|Propionibacteriales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_1201106_63	590998.Celf_1204	3.196e-22	111.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158390_k127_1201106_58	1120949.KB903294_gene4476	2.52e-31	134.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4DEUJ@85008|Micromonosporales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158390_k127_1201106_66	1121926.AXWO01000019_gene1866	4.015e-19	95.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	-
SRR25158390_k127_1201106_52	547163.BN979_05363	5.759e-38	152.0	COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria,239GS@1762|Mycobacteriaceae	201174|Actinobacteria	J	heat shock protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRR25158390_k127_1201106_51	1229780.BN381_350150	1.866e-40	162.0	COG3536@1|root,COG3536@2|Bacteria,2HDP4@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
SRR25158390_k127_1201106_32	926560.KE387023_gene2757	3.004e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,1WNJF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1201106_71	1206730.BAGA01000125_gene4122	7.552e-12	68.0	COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4G3TS@85025|Nocardiaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR25158390_k127_1201106_45	1282876.BAOK01000001_gene3434	5.657e-52	204.0	COG1917@1|root,COG1917@2|Bacteria,1RB86@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	1.13.11.41	ko:K05913	ko00363,ko01120,map00363,map01120	-	R01305	RC00415,RC01565	ko00000,ko00001,ko01000	-	-	-	Cupin_7
SRR25158390_k127_1201106_34	304371.MCP_2977	4.598e-66	240.0	arCOG11014@1|root,arCOG11014@2157|Archaea	2157|Archaea	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_1201106_8	561175.KB894098_gene5160	3.329e-151	486.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4EHYK@85012|Streptosporangiales	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1201106_1	1313172.YM304_13290	3.009e-222	693.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1201106_7	390989.JOEG01000014_gene3137	1.69e-151	484.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158390_k127_1201106_24	1313172.YM304_27860	1.08e-83	294.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CNDI@84992|Acidimicrobiia	84992|Acidimicrobiia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158390_k127_1201106_59	1313172.YM304_27870	4.235e-31	138.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	perM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
SRR25158390_k127_1201106_62	1206732.BAGD01000097_gene4160	3.784e-24	109.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,4G1X9@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158390_k127_1201106_69	1386089.N865_05940	3.64e-15	82.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4FEE3@85021|Intrasporangiaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_1201106_46	1463820.JOGW01000005_gene3327	3.66e-51	191.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_1201106_39	358823.DF19_06475	7.629e-58	206.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1201106_53	561175.KB894093_gene4027	8.811e-38	143.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4EJZH@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_1201106_73	196162.Noca_0158	8.418e-06	55.0	2F62M@1|root,33YKZ@2|Bacteria,2GX5M@201174|Actinobacteria,4DSQ2@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1201106_36	1463820.JOGW01000026_gene4972	4.43e-62	239.0	COG4585@1|root,COG4585@2|Bacteria,2I9E9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158390_k127_1201106_30	1123321.KB905813_gene1469	2.732e-80	279.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_1201106_0	479434.Sthe_2199	3.403e-239	763.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_1201106_50	83332.Rv0582	7.945e-41	155.0	COG2402@1|root,COG2402@2|Bacteria,2HZHQ@201174|Actinobacteria,23BTY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_1201106_68	1108045.GORHZ_121_00120	2.211e-16	82.0	2BT89@1|root,32NDN@2|Bacteria,2HDWZ@201174|Actinobacteria	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_1201106_72	1048339.KB913029_gene2623	1.162e-08	60.0	2E73E@1|root,331MX@2|Bacteria,2IRHV@201174|Actinobacteria,4EVZR@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_1201106_25	1123258.AQXZ01000014_gene5018	1.138e-83	291.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4FW1K@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_1201106_11	1386089.N865_16820	2.108e-138	460.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4FFS7@85021|Intrasporangiaceae	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_1201106_55	1313172.YM304_09240	1.254e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,2IHVZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1201106_22	1118054.CAGW01000005_gene3791	1.19e-86	303.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_1201106_2	1380393.JHVP01000004_gene612	4.039e-213	678.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_1201106_28	1463858.JOHR01000014_gene5138	8.243e-81	282.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria	201174|Actinobacteria	K	PFAM ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158390_k127_1201106_41	1380390.JIAT01000013_gene123	9.297e-56	206.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158390_k127_1201106_26	1184609.KILIM_005_00510	1.14e-83	287.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158390_k127_1201106_43	1380370.JIBA01000017_gene2939	1.708e-54	213.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4FH4A@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_1201106_27	1246448.ANAZ01000015_gene5975	3.775e-81	284.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHS4@85012|Streptosporangiales	201174|Actinobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_1201106_18	443598.AUFA01000011_gene481	7.15e-102	338.0	COG1073@1|root,COG1073@2|Bacteria,1R0B5@1224|Proteobacteria,2TYPP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_1201106_74	649638.Trad_2258	0.0007259	45.0	28NV2@1|root,2ZBT9@2|Bacteria	2|Bacteria	S	YKOF-related Family	ykoF	-	-	-	-	-	-	-	-	-	-	-	Ykof
SRR25158390_k127_1201106_57	1429046.RR21198_4501	3.923e-32	136.0	COG0500@1|root,COG2226@2|Bacteria,2HFGE@201174|Actinobacteria,4FV65@85025|Nocardiaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_1201106_56	101510.RHA1_ro04016	3.417e-33	135.0	2EE1U@1|root,337WK@2|Bacteria,2IR2G@201174|Actinobacteria,4G4NI@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
SRR25158390_k127_1201106_16	1380356.JNIK01000003_gene1112	1.058e-111	372.0	28HWH@1|root,2Z82E@2|Bacteria,2H3DV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1201106_3	525904.Tter_2675	3.471e-191	612.0	COG0028@1|root,COG0028@2|Bacteria,2NNMW@2323|unclassified Bacteria	2|Bacteria	EH	thiamine pyrophosphate protein TPP binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_1201106_13	1394178.AWOO02000024_gene5577	4.123e-127	419.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4EG5D@85012|Streptosporangiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_1201106_33	1380390.JIAT01000010_gene3432	7.58e-74	262.0	COG2267@1|root,COG2267@2|Bacteria,2IKAA@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_1201106_47	35754.JNYJ01000027_gene6203	2.469e-50	186.0	COG0346@1|root,COG0346@2|Bacteria,2IM43@201174|Actinobacteria,4DG2U@85008|Micromonosporales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1201106_31	67315.JOBD01000002_gene2906	8.895e-77	261.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158390_k127_1201106_14	1343740.M271_06895	2.086e-122	398.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1201106_21	290399.Arth_3711	1.889e-88	310.0	COG0454@1|root,COG0456@2|Bacteria,2GY1D@201174|Actinobacteria,1WAUV@1268|Micrococcaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_1201106_20	33876.JNXY01000021_gene4782	2.616e-99	338.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1201106_42	649831.L083_7332	6.709e-55	207.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	waaD	-	2.4.1.56	ko:K00713,ko:K03280	ko00540,ko01100,map00540,map01100	M00080	R01996	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4,GT9	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1201106_64	33876.JNXY01000021_gene4781	6.185e-21	97.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158390_k127_1201106_19	33876.JNXY01000021_gene4780	1.141e-101	344.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DBD5@85008|Micromonosporales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
SRR25158390_k127_1201106_6	710686.Mycsm_01466	1.978e-171	568.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2I3VK@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2,RibD_C
SRR25158390_k127_1201106_37	1487953.JMKF01000088_gene5471	1.022e-59	215.0	COG3663@1|root,COG3663@2|Bacteria,1G66F@1117|Cyanobacteria	1117|Cyanobacteria	L	COG3663 G T U mismatch-specific DNA glycosylase	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_1201106_35	671143.DAMO_1943	1.258e-63	229.0	COG0428@1|root,COG0428@2|Bacteria,2NQN6@2323|unclassified Bacteria	2|Bacteria	P	Zinc transporter zupT	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
SRR25158390_k127_1201106_48	671143.DAMO_1944	6.519e-48	177.0	COG0053@1|root,COG1237@1|root,COG0053@2|Bacteria,COG1237@2|Bacteria,2NPQA@2323|unclassified Bacteria	2|Bacteria	P	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K04088,ko:K06897	ko00790,map00790	M00742	R10339	RC00121	ko00000,ko00001,ko00002,ko01000	-	-	-	Cation_efflux,Lactamase_B
SRR25158390_k127_1201106_61	219305.MCAG_02552	1.536e-27	120.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158390_k127_1201106_9	219305.MCAG_02552	2.123e-145	484.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158390_k127_1201106_23	1313172.YM304_38300	5.592e-84	303.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_1201106_65	1313172.YM304_38290	2.115e-19	96.0	COG0577@1|root,COG0577@2|Bacteria,2GMC4@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	hrtB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_1203485_28	298655.KI912267_gene7452	2.254e-20	95.0	2DQKP@1|root,337GR@2|Bacteria,2GU0C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1203485_19	1229780.BN381_10037	3.122e-86	292.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_1203485_15	298654.FraEuI1c_1763	1.3e-90	335.0	COG0411@1|root,COG0411@2|Bacteria,2H5WA@201174|Actinobacteria	201174|Actinobacteria	E	PFAM ABC transporter related	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_1203485_0	298654.FraEuI1c_1762	1.482e-289	907.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1203485_8	298654.FraEuI1c_1761	5.389e-143	469.0	COG0683@1|root,COG0683@2|Bacteria,2IPWY@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_1203485_27	479432.Sros_3835	6.617e-26	119.0	COG0703@1|root,COG0703@2|Bacteria,2IQZ8@201174|Actinobacteria,4EK2Z@85012|Streptosporangiales	201174|Actinobacteria	E	Shikimate kinase	-	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158390_k127_1203485_25	635013.TherJR_1369	3.161e-33	137.0	COG0463@1|root,COG0463@2|Bacteria,1UJPS@1239|Firmicutes,25F7Y@186801|Clostridia	186801|Clostridia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1203485_18	1313172.YM304_05030	1.159e-86	292.0	COG1051@1|root,COG1051@2|Bacteria,2HG6C@201174|Actinobacteria,4CN3B@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
SRR25158390_k127_1203485_3	1313172.YM304_04990	1.899e-185	607.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158390_k127_1203485_23	1449976.KALB_7322	1.19e-45	167.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4E4D5@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158390_k127_1203485_5	1313172.YM304_10090	6.522e-158	511.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CNTR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158390_k127_1203485_7	2002.JOEQ01000008_gene1059	2.838e-145	476.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EIFF@85012|Streptosporangiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_1203485_22	525904.Tter_1708	2.306e-69	254.0	COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
SRR25158390_k127_1203485_17	1229780.BN381_130053	2.135e-89	300.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria	201174|Actinobacteria	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR25158390_k127_1203485_9	1313172.YM304_20070	1.016e-129	429.0	COG0683@1|root,COG0683@2|Bacteria,2HFKF@201174|Actinobacteria,4CP0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_1203485_13	526225.Gobs_3206	1.657e-105	362.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4EUWF@85013|Frankiales	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_1203485_12	443218.AS9A_1474	2.286e-107	367.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,23EVZ@1762|Mycobacteriaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_1203485_10	1048339.KB913029_gene4523	8.186e-128	416.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4EUKY@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1203485_11	1380393.JHVP01000003_gene929	6.096e-110	371.0	COG0559@1|root,COG4932@1|root,COG0559@2|Bacteria,COG4932@2|Bacteria,2GMAY@201174|Actinobacteria,4ESA3@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
SRR25158390_k127_1203485_21	1229780.BN381_150097	3.75e-79	270.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
SRR25158390_k127_1203485_1	266117.Rxyl_0146	2.438e-252	804.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4CQ1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SRR25158390_k127_1203485_14	1313172.YM304_04940	1.088e-91	310.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CN5S@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158390_k127_1203485_20	1136417.AZWE01000008_gene2241	2.474e-83	309.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_1203485_16	369723.Strop_2135	2.129e-90	325.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_1203485_6	644283.Micau_2845	5.692e-153	501.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1203485_2	1137269.AZWL01000009_gene3781	1.711e-190	617.0	2DBGS@1|root,2Z95N@2|Bacteria,2ICPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1203485_26	1229780.BN381_70028	2.173e-27	117.0	COG5349@1|root,COG5349@2|Bacteria,2HCSH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158390_k127_1203485_24	357808.RoseRS_0245	1.093e-37	153.0	COG0406@1|root,COG0406@2|Bacteria,2GAE9@200795|Chloroflexi,375RN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_1203485_4	525909.Afer_1846	8.833e-176	556.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158390_k127_1226765_1	1313172.YM304_30640	2.976e-110	374.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_1226765_3	44060.JODL01000023_gene4965	1.464e-38	151.0	COG2072@1|root,COG3832@1|root,COG2072@2|Bacteria,COG3832@2|Bacteria,2GMDH@201174|Actinobacteria	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase
SRR25158390_k127_1226765_2	1146883.BLASA_0490	1.914e-108	373.0	COG2865@1|root,COG2865@2|Bacteria,2I3IG@201174|Actinobacteria,4EXAT@85013|Frankiales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SRR25158390_k127_1226765_0	1146883.BLASA_1977	1.283e-139	455.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4EUKK@85013|Frankiales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_1226765_4	298655.KI912266_gene5532	4.198e-33	130.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
SRR25158390_k127_1226840_9	1120949.KB903339_gene8068	6.736e-120	398.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_1226840_16	710696.Intca_0371	2.767e-80	273.0	COG1765@1|root,COG1765@2|Bacteria,2IG8A@201174|Actinobacteria,4FJTH@85021|Intrasporangiaceae	201174|Actinobacteria	O	redox protein regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_1226840_19	1229203.KI301992_gene922	6.889e-46	171.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,3UXAC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CO	Thioredoxin	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_1226840_0	232721.Ajs_2162	4.239e-290	918.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,2VK07@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glycosyl hydrolase family 65 central catalytic domain protein	-	-	2.4.1.64,2.4.1.8	ko:K00691,ko:K05342	ko00500,ko01100,map00500,map01100	-	R01555,R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158390_k127_1226840_12	1206726.BAFV01000065_gene4534	8.143e-88	297.0	COG0637@1|root,COG1554@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,COG1877@2|Bacteria,2GKEV@201174|Actinobacteria,4FU49@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	otsB1	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	3.1.3.12,3.2.1.28	ko:K01087,ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010,R02778	RC00017,RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
SRR25158390_k127_1226840_10	1476876.JOJO01000013_gene4633	2.094e-107	358.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158390_k127_1226840_4	1283287.KB822580_gene1597	2.83e-149	484.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4DN00@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1226840_22	1078020.KEK_09202	1.834e-28	132.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria,235WU@1762|Mycobacteriaceae	201174|Actinobacteria	S	Nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_1226840_6	710685.MycrhN_0140	3.677e-142	468.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,237UH@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158390_k127_1226840_15	1449353.JQMQ01000004_gene6252	2.785e-82	284.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1226840_24	1229780.BN381_110065	5.18e-24	111.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1226840_25	1002672.SAR11G3_00960	8.83e-17	85.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,4BQXA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	MA20_31615	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_1226840_7	1079986.JH164861_gene7150	1.412e-125	421.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_1226840_11	1429046.RR21198_1297	1.146e-96	324.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1226840_2	710696.Intca_2072	2.891e-185	589.0	COG0477@1|root,COG2814@2|Bacteria,2GNBV@201174|Actinobacteria,4FIKA@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1226840_1	452863.Achl_4514	8.381e-195	620.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,1W87H@1268|Micrococcaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_1226840_20	1449976.KALB_6917	6.238e-42	165.0	COG4308@1|root,COG4308@2|Bacteria,2IN4A@201174|Actinobacteria,4E4Z1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	ephG	GO:0003674,GO:0003824,GO:0004301,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016801,GO:0016803,GO:0018904,GO:0033963,GO:0044237,GO:0044281,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0097176,GO:1901360	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
SRR25158390_k127_1226840_21	656024.FsymDg_2326	1.756e-39	164.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K16554,ko:K21473	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011,ko02000	8.A.3.1	-	-	DUF2325,GNVR,Peptidase_M23
SRR25158390_k127_1226840_3	656024.FsymDg_2325	4.111e-155	500.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4ESWQ@85013|Frankiales	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.87	ko:K07806,ko:K21337	ko00520,ko00523,ko01130,ko01503,ko02020,map00520,map00523,map01130,map01503,map02020	M00721,M00761	R07659,R11467	RC00006,RC01514,RC03445	ko00000,ko00001,ko00002,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158390_k127_1226840_14	656024.FsymDg_2324	4.247e-84	284.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	mpg2	-	-	ko:K21210	ko01059,ko01130,map01059,map01130	-	R11429	RC00002	ko00000,ko00001	-	-	-	CBS,NTP_transferase
SRR25158390_k127_1226840_13	656024.FsymDg_2329	1.792e-87	312.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158390_k127_1226840_17	656024.FsymDg_2322	6.19e-72	257.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158390_k127_1226840_8	656024.FsymDg_2321	1.293e-123	415.0	COG2244@1|root,COG2244@2|Bacteria,2IDI4@201174|Actinobacteria,4EWT8@85013|Frankiales	201174|Actinobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C,Wzy_C
SRR25158390_k127_1226840_18	656024.FsymDg_2320	8.427e-71	252.0	COG1215@1|root,COG1215@2|Bacteria,2GMWF@201174|Actinobacteria,4ET6K@85013|Frankiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1226840_5	656024.FsymDg_2327	2.645e-147	473.0	COG0451@1|root,COG0451@2|Bacteria,2I2ZM@201174|Actinobacteria,4EXHI@85013|Frankiales	201174|Actinobacteria	M	Male sterility protein	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678,ko:K21211	ko00520,ko00521,ko00523,ko00525,ko01055,ko01059,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01059,map01100,map01130	M00361,M00793	R01384,R06513,R11430	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_123748_8	58344.JOEL01000012_gene2544	1.311e-86	306.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_123748_15	298655.KI912266_gene6559	1.371e-13	79.0	2E37T@1|root,32Y7G@2|Bacteria,2HKTZ@201174|Actinobacteria,4EWSP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158390_k127_123748_0	1229780.BN381_130375	1.323e-264	841.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	CarboxypepD_reg,MMPL
SRR25158390_k127_123748_14	247490.KSU1_C0726	1.547e-22	105.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158390_k127_123748_2	926564.KI911765_gene4541	3.953e-157	526.0	COG3103@1|root,COG4991@2|Bacteria,2GJE2@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRR25158390_k127_123748_4	1283283.ATXA01000008_gene2989	1.226e-130	423.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_123748_3	1298863.AUEP01000011_gene627	6.916e-143	485.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2GM4U@201174|Actinobacteria,4DUTC@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158390_k127_123748_12	33876.JNXY01000052_gene6395	9.701e-30	138.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,4DMHP@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158390_k127_123748_1	1206731.BAGB01000159_gene6110	8.766e-180	582.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4FVRW@85025|Nocardiaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
SRR25158390_k127_123748_10	1219045.BV98_003710	2.666e-55	198.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,2K4VD@204457|Sphingomonadales	204457|Sphingomonadales	K	DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158390_k127_123748_7	1229780.BN381_210069	8.69e-87	298.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158390_k127_123748_5	471852.Tcur_1579	1.936e-95	321.0	COG0596@1|root,COG0596@2|Bacteria,2HMX1@201174|Actinobacteria,4EHZ7@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	ephC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_123748_6	1313172.YM304_14260	2.191e-88	312.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CNWS@84992|Acidimicrobiia	84992|Acidimicrobiia	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158390_k127_123748_11	649831.L083_3922	3.473e-41	162.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,4DDUA@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_123748_9	1192034.CAP_8545	9.697e-56	207.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria,43AS2@68525|delta/epsilon subdivisions,2X666@28221|Deltaproteobacteria,2Z27D@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_123748_13	1313172.YM304_14250	9.53e-24	101.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CMYB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_125121_4	211165.AJLN01000101_gene4389	1.017e-56	214.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1JHXE@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_125121_7	134676.ACPL_3785	2.544e-25	118.0	COG1737@1|root,COG1737@2|Bacteria,2GMN2@201174|Actinobacteria,4DBIB@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158390_k127_125121_2	1070319.CAGGBEG34_230024	1.762e-89	302.0	COG0688@1|root,COG0688@2|Bacteria,1NNH6@1224|Proteobacteria	1224|Proteobacteria	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158390_k127_125121_0	1223523.H340_17487	5.443e-136	439.0	COG1834@1|root,COG1834@2|Bacteria,2H33J@201174|Actinobacteria	201174|Actinobacteria	E	N-dimethylarginine dimethylaminohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158390_k127_125121_6	1077285.AGDG01000039_gene4057	9.731e-50	198.0	COG0534@1|root,COG0534@2|Bacteria,4NFIR@976|Bacteroidetes,2FMSA@200643|Bacteroidia,4AN4V@815|Bacteroidaceae	976|Bacteroidetes	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158390_k127_125121_1	1394178.AWOO02000072_gene443	1.123e-100	335.0	COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_125121_3	1386089.N865_18735	2.56e-88	298.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4FIS4@85021|Intrasporangiaceae	201174|Actinobacteria	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158390_k127_125121_5	1463821.JOGR01000009_gene1850	2.861e-50	186.0	COG0243@1|root,COG0243@2|Bacteria,2GJ62@201174|Actinobacteria,4F07N@85014|Glycomycetales	201174|Actinobacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_1286944_7	105425.BBPL01000015_gene2607	2.361e-25	120.0	COG0346@1|root,COG0346@2|Bacteria,2HTC1@201174|Actinobacteria,2NMQF@228398|Streptacidiphilus	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1286944_8	500153.JOEK01000017_gene3216	9.663e-23	109.0	COG2334@1|root,COG2334@2|Bacteria,2GU3Q@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1286944_4	1121877.JQKF01000009_gene556	5.491e-45	170.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CN5G@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158390_k127_1286944_5	525909.Afer_0389	1.293e-44	173.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CN6B@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158390_k127_1286944_0	1313172.YM304_07900	3.49e-102	338.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CMU4@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158390_k127_1286944_2	1229780.BN381_350060	4.76e-62	216.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,3UWIZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158390_k127_1286944_1	1229780.BN381_350058	7.923e-79	274.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,3UWJ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158390_k127_1286944_9	1229780.BN381_350057	3.235e-20	95.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158390_k127_1286944_12	207954.MED92_04552	0.0002299	47.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158390_k127_1286944_3	1229780.BN381_610018	1.242e-59	212.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1286944_10	525909.Afer_0383	5.534e-18	86.0	COG0267@1|root,COG0267@2|Bacteria,2HH2Z@201174|Actinobacteria,4CP34@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158390_k127_1286944_11	1121926.AXWO01000002_gene1546	3.667e-16	78.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4EY5Q@85014|Glycomycetales	201174|Actinobacteria	J	Elongation factor Tu C-terminal domain	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158390_k127_1308492_6	100226.SCO3449	1.286e-20	94.0	291EA@1|root,2ZP15@2|Bacteria,2ITEP@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_1308492_1	479433.Caci_7018	1.022e-81	278.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,2GKCA@201174|Actinobacteria	201174|Actinobacteria	O	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158390_k127_1308492_8	216594.MMAR_1621	1.46e-07	63.0	COG0664@1|root,COG0664@2|Bacteria,2IB1J@201174|Actinobacteria,237EQ@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21884	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_1308492_3	1246995.AFR_23035	3.695e-42	164.0	2DW5E@1|root,33YM7@2|Bacteria,2GSAI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1308492_4	1385520.N802_11150	2.812e-23	108.0	COG3339@1|root,COG3339@2|Bacteria,2IR8D@201174|Actinobacteria,4FJD6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1308492_9	1206101.AZXC01000016_gene3443	2.57e-07	59.0	2AYNY@1|root,31QTF@2|Bacteria,2ISMX@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_1308492_7	1283299.AUKG01000006_gene795	1.502e-12	74.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria	84995|Rubrobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158390_k127_1308492_0	35754.JNYJ01000003_gene6464	6.768e-187	595.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4D9EC@85008|Micromonosporales	201174|Actinobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_1308492_5	675635.Psed_1298	1.699e-22	105.0	COG0695@1|root,COG0695@2|Bacteria,2HNF0@201174|Actinobacteria,4E6IC@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158390_k127_1308492_2	110319.CF8_0377	1.659e-57	204.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4DNZV@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_1317577_4	1906.SFRA_18070	1.251e-105	352.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158390_k127_1317577_6	298655.KI912266_gene606	2.153e-54	195.0	COG2020@1|root,COG2020@2|Bacteria,2IN0C@201174|Actinobacteria,4EVQB@85013|Frankiales	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158390_k127_1317577_8	994479.GL877878_gene1561	6.683e-21	96.0	2EH65@1|root,3351X@2|Bacteria,2GQUG@201174|Actinobacteria,4E74D@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876
SRR25158390_k127_1317577_1	1123023.JIAI01000002_gene5486	1.291e-212	673.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4DZNN@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_1317577_2	1120950.KB892776_gene796	2.307e-188	598.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158390_k127_1317577_5	1370120.AUWR01000026_gene2567	3.262e-66	248.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,2387T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158390_k127_1317577_0	292415.Tbd_1072	4e-323	1002.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VS7B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
SRR25158390_k127_1317577_9	1463920.JOGB01000034_gene1318	4.465e-05	57.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c_2,PAS,PAS_4,SpoIIE,sCache_3_2
SRR25158390_k127_1317577_7	1168289.AJKI01000010_gene1631	1.847e-30	141.0	COG5002@1|root,COG5002@2|Bacteria,4PIA3@976|Bacteroidetes,2G21N@200643|Bacteroidia,3XKPD@558415|Marinilabiliaceae	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
SRR25158390_k127_1317577_3	1298880.AUEV01000006_gene4307	6.842e-115	377.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,2GNNG@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
SRR25158390_k127_1318735_0	1229780.BN381_130373	5.525e-180	567.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_1318735_11	37919.EP51_29545	2.812e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,2IFC4@201174|Actinobacteria,4G1I4@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_1318735_8	1380356.JNIK01000002_gene4858	2.466e-57	204.0	COG2259@1|root,COG2259@2|Bacteria,2IJ0I@201174|Actinobacteria,4ET1G@85013|Frankiales	201174|Actinobacteria	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158390_k127_1318735_1	981369.JQMJ01000004_gene3588	1.175e-179	570.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria	201174|Actinobacteria	P	pyridine nucleotide-disulphide oxidoreductase	fccB	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_1318735_3	1229780.BN381_130049	9.449e-130	435.0	COG0318@1|root,COG0318@2|Bacteria,2H33T@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_1318735_6	1424334.W822_01165	3.531e-72	252.0	29FE7@1|root,302BX@2|Bacteria,1NXED@1224|Proteobacteria,2W8VK@28216|Betaproteobacteria,3T7DI@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1318735_5	1229780.BN381_60058	1.875e-80	272.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,3UWSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158390_k127_1318735_9	426716.JOAJ01000001_gene1425	1.074e-50	184.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4G1IX@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158390_k127_1318735_7	266117.Rxyl_0283	3.689e-68	241.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158390_k127_1318735_4	469371.Tbis_2109	4.721e-81	277.0	29QBK@1|root,30BAT@2|Bacteria,2IH7J@201174|Actinobacteria,4EC9R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1318735_2	749414.SBI_00971	2.757e-147	475.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_1318735_10	1265310.CCBD010000069_gene466	5.043e-21	99.0	2BG9C@1|root,32A6J@2|Bacteria,2GPNJ@201174|Actinobacteria,23AWE@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1347253_0	1229780.BN381_630011	2.429e-125	431.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,3UWTN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_1347253_1	1229780.BN381_630010	2.228e-101	347.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,3UXD2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158390_k127_1347253_3	1313172.YM304_32820	1.311e-13	79.0	2CK2C@1|root,2ZY21@2|Bacteria,2HE72@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1347253_2	477641.MODMU_0850	8.504e-56	222.0	COG0577@1|root,COG0577@2|Bacteria,2IE56@201174|Actinobacteria	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158390_k127_1369209_1	1121396.KB892944_gene3036	5.311e-191	613.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158390_k127_1369209_5	675635.Psed_4548	4.283e-36	157.0	COG0454@1|root,COG0456@2|Bacteria,2I8J8@201174|Actinobacteria,4E71G@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_1369209_0	1229780.BN381_130282	0.0	1037.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1369209_3	1313172.YM304_16870	1.475e-96	324.0	COG2267@1|root,COG2267@2|Bacteria,2GJNF@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158390_k127_1369209_2	1313172.YM304_26380	5.074e-180	583.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CMS1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_1369209_4	1313172.YM304_26370	2.809e-72	272.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4CNDA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
SRR25158390_k127_1369209_6	1313172.YM304_26330	5.876e-27	125.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4CN2B@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
SRR25158390_k127_1392138_3	1229780.BN381_170040	2.922e-86	302.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,3UW69@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158390_k127_1392138_6	1463934.JOCF01000024_gene6078	2.363e-12	78.0	COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	ydgJ	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_1392138_2	487521.OCU_25380	1.237e-148	484.0	COG1363@1|root,COG1363@2|Bacteria,2ICG5@201174|Actinobacteria,235ZX@1762|Mycobacteriaceae	201174|Actinobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158390_k127_1392138_1	246196.MSMEI_2531	1.312e-225	733.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,2GN0U@201174|Actinobacteria,2356T@1762|Mycobacteriaceae	201174|Actinobacteria	HJK	acetyltransferase	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158390_k127_1392138_0	1078020.KEK_18413	3.802e-287	893.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,232RF@1762|Mycobacteriaceae	201174|Actinobacteria	E	Asparagine synthase	asnB_1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158390_k127_1392138_4	1449346.JQMO01000003_gene3404	3.144e-43	173.0	COG2021@1|root,COG2021@2|Bacteria,2I2Z2@201174|Actinobacteria,2M0M9@2063|Kitasatospora	201174|Actinobacteria	E	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_1392138_5	479434.Sthe_0203	9.164e-15	82.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158390_k127_1399305_3	357808.RoseRS_1410	3.44e-58	206.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_1399305_7	471852.Tcur_3022	1.556e-41	167.0	COG1393@1|root,COG1393@2|Bacteria,2IHRP@201174|Actinobacteria,4EK6G@85012|Streptosporangiales	201174|Actinobacteria	P	ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRR25158390_k127_1399305_4	1121937.AUHJ01000001_gene750	6.015e-57	212.0	COG1028@1|root,COG1028@2|Bacteria,1R3VH@1224|Proteobacteria,1RRZ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_1399305_5	1123320.KB889562_gene6740	1.839e-53	205.0	COG1024@1|root,COG1024@2|Bacteria,2IAFJ@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_1399305_6	365528.KB891137_gene399	3.561e-49	195.0	COG0496@1|root,COG0496@2|Bacteria,2IRBR@201174|Actinobacteria,4EVR8@85013|Frankiales	201174|Actinobacteria	S	Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158390_k127_1399305_0	208439.AJAP_11345	2.815e-167	555.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4DZMM@85010|Pseudonocardiales	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRR25158390_k127_1399305_8	1348663.KCH_65830	1.894e-38	154.0	COG1309@1|root,COG1309@2|Bacteria,2IA75@201174|Actinobacteria,2M2NI@2063|Kitasatospora	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_1399305_9	1089546.AQUI01000002_gene2255	3.521e-22	107.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4093N@622450|Actinopolysporales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1399305_2	1380356.JNIK01000013_gene4169	1.371e-93	332.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158390_k127_1399305_1	285535.JOEY01000044_gene1299	1.828e-110	372.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_1413120_1	685727.REQ_18420	1.261e-65	239.0	COG2304@1|root,COG4965@1|root,COG2304@2|Bacteria,COG4965@2|Bacteria,2H577@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF,VWA_2
SRR25158390_k127_1413120_2	526225.Gobs_3420	4.709e-58	213.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria	201174|Actinobacteria	NU	Type ii secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_1413120_3	1386089.N865_09995	6.864e-56	208.0	COG0305@1|root,COG0305@2|Bacteria,2I9NH@201174|Actinobacteria,4FER9@85021|Intrasporangiaceae	201174|Actinobacteria	L	KaiC	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_C
SRR25158390_k127_1413120_5	525909.Afer_1930	5.569e-24	108.0	2EG9A@1|root,33A12@2|Bacteria,2GQ7U@201174|Actinobacteria,4CNB5@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1413120_4	1121382.JQKG01000023_gene1521	2.358e-32	132.0	COG2832@1|root,COG2832@2|Bacteria,1WK7X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
SRR25158390_k127_1413120_0	1229780.BN381_30034	4.401e-83	284.0	COG2267@1|root,COG2267@2|Bacteria,2ICDY@201174|Actinobacteria	201174|Actinobacteria	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
SRR25158390_k127_141939_13	96561.Dole_2360	1.483e-31	132.0	COG3356@1|root,COG3356@2|Bacteria,1QW1Q@1224|Proteobacteria,43BRP@68525|delta/epsilon subdivisions,2X72J@28221|Deltaproteobacteria,2MMRW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158390_k127_141939_4	1123024.AUII01000044_gene601	3.865e-125	411.0	COG1063@1|root,COG1063@2|Bacteria,2GKFG@201174|Actinobacteria,4E0X4@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
SRR25158390_k127_141939_14	590998.Celf_0778	3.479e-26	124.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_141939_0	1150864.MILUP08_45152	0.0	1388.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4D8EW@85008|Micromonosporales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158390_k127_141939_16	1343740.M271_36570	1.37e-11	76.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria	201174|Actinobacteria	S	maleylpyruvate isomerase	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_141939_11	1341646.CBMO010000106_gene4047	2.929e-36	144.0	2DMP1@1|root,32SS8@2|Bacteria,2IJVX@201174|Actinobacteria,239AG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SRR25158390_k127_141939_9	1056816.JAFQ01000004_gene1597	1.343e-45	173.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FZ9I@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
SRR25158390_k127_141939_8	909613.UO65_4894	8.569e-66	235.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria,4EAFW@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_141939_1	1464048.JNZS01000014_gene3102	1.897e-144	486.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4D9AC@85008|Micromonosporales	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158390_k127_141939_10	1120950.KB892773_gene1079	9.214e-42	164.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4DR5F@85009|Propionibacteriales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_141939_6	446471.Xcel_2621	9.831e-121	404.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4F3BD@85017|Promicromonosporaceae	201174|Actinobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_141939_15	1313172.YM304_29470	5.176e-24	107.0	2C1D9@1|root,2ZD16@2|Bacteria,2HBJG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_141939_3	477641.MODMU_3515	3.426e-127	420.0	COG1915@1|root,COG1915@2|Bacteria,2GMEZ@201174|Actinobacteria,4EUTP@85013|Frankiales	201174|Actinobacteria	S	PFAM LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR25158390_k127_141939_7	1068980.ARVW01000001_gene8075	1.52e-67	261.0	COG1834@1|root,COG1834@2|Bacteria,2GNTN@201174|Actinobacteria,4DYJJ@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158390_k127_141939_2	222534.KB893672_gene2985	3.879e-142	459.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EUYX@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	drrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_141939_5	222534.KB893672_gene2986	7.71e-122	396.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4EUS8@85013|Frankiales	201174|Actinobacteria	V	ABC-2 family transporter protein	drrB	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158390_k127_141939_12	479431.Namu_4659	5.64e-32	134.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4EVPW@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158390_k127_1475724_4	1229780.BN381_40079	4.001e-80	275.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,3UWQB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158390_k127_1475724_11	1305732.JAGG01000001_gene2114	8.281e-44	184.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,4FSI4@85023|Microbacteriaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158390_k127_1475724_6	1313172.YM304_25680	2.222e-56	211.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CN98@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_1475724_0	1996.JOFO01000001_gene3977	3.257e-249	795.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4EFSZ@85012|Streptosporangiales	201174|Actinobacteria	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158390_k127_1475724_9	1313172.YM304_25690	1.175e-46	176.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CN5F@84992|Acidimicrobiia	84992|Acidimicrobiia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158390_k127_1475724_7	477641.MODMU_2670	5.787e-53	190.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4ESK3@85013|Frankiales	201174|Actinobacteria	T	FHA domain containing protein	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158390_k127_1475724_10	1313172.YM304_25710	6.443e-46	185.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CN7E@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_1475724_12	1313172.YM304_25720	6.041e-40	157.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158390_k127_1475724_8	1229780.BN381_40086	7.723e-50	190.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,3UWPC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_1475724_2	1313172.YM304_25740	1.321e-131	435.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CMQS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Glycine cleavage T-protein C-terminal barrel domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158390_k127_1475724_1	365528.KB891263_gene641	2.8e-155	503.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4ERPB@85013|Frankiales	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158390_k127_1475724_13	471852.Tcur_2668	2.47e-30	127.0	COG5485@1|root,COG5485@2|Bacteria,2GMYI@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158390_k127_1475724_3	251221.35214861	6.893e-113	369.0	COG0235@1|root,COG0235@2|Bacteria,1G10W@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158390_k127_1475724_5	1179773.BN6_39960	1.78e-58	215.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4E1BP@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
SRR25158390_k127_1496237_7	1210046.B277_00060	1.615e-75	255.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4FENI@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
SRR25158390_k127_1496237_3	1283283.ATXA01000005_gene2158	4.83e-149	480.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4ERPG@85013|Frankiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_1496237_2	1229780.BN381_80323	2.889e-167	536.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,3UW9C@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158390_k127_1496237_8	1122175.ATXU01000004_gene2182	1.728e-36	151.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4FKHM@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158390_k127_1496237_4	1313172.YM304_27020	5.115e-89	304.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CN5X@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158390_k127_1496237_9	269800.Tfu_1962	9.066e-18	93.0	COG0778@1|root,COG0778@2|Bacteria,2I5R3@201174|Actinobacteria,4EKY9@85012|Streptosporangiales	201174|Actinobacteria	C	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876,DUF1918
SRR25158390_k127_1496237_1	1313172.YM304_27040	1.505e-205	649.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CMWG@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158390_k127_1496237_5	1229780.BN381_10244	1.669e-88	314.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1496237_0	1048339.KB913029_gene1969	4.725e-247	807.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_1496237_6	1229780.BN381_80311	2.863e-80	269.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,3UW96@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158390_k127_1498867_1	1313172.YM304_03920	5.328e-98	334.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CMZ7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158390_k127_1498867_3	1211815.CBYP010000068_gene195	5.846e-61	221.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158390_k127_1498867_2	269800.Tfu_2303	1.853e-76	265.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,4EIJX@85012|Streptosporangiales	201174|Actinobacteria	P	TrkA-C domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158390_k127_1498867_0	446470.Snas_1512	9.185e-139	456.0	COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,4EZ6C@85014|Glycomycetales	201174|Actinobacteria	P	Cation transport protein	ktrB	-	-	-	-	-	-	-	-	-	-	-	TrkH
SRR25158390_k127_1498867_5	240016.ABIZ01000001_gene684	1.996e-49	196.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Acetyltransf_1,Acetyltransf_7,Amidase_2,rRNA_methylase
SRR25158390_k127_1498867_4	1089550.ATTH01000001_gene1564	5.898e-50	180.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1FISX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
SRR25158390_k127_1500278_2	1229780.BN381_150043	7.659e-127	411.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWCM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_1500278_0	1123322.KB904713_gene5176	9.846e-301	950.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158390_k127_1500278_12	1229780.BN381_150141	2.464e-52	192.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,3UWKT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR25158390_k127_1500278_10	1313172.YM304_03460	4.864e-64	234.0	COG0470@1|root,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	holB	-	2.7.7.7	ko:K02341,ko:K02343,ko:K09384	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158390_k127_1500278_13	83332.Rv0659c	4.102e-43	160.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_1500278_15	1121929.KB898663_gene899	3.951e-07	59.0	2DT36@1|root,33IHH@2|Bacteria,1W296@1239|Firmicutes,4HZMN@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1500278_4	1206732.BAGD01000278_gene6319	8.697e-104	362.0	COG1306@1|root,COG1306@2|Bacteria,2GNVR@201174|Actinobacteria,4FVN2@85025|Nocardiaceae	201174|Actinobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
SRR25158390_k127_1500278_5	525909.Afer_1918	5.708e-86	287.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1500278_14	525909.Afer_1917	5.654e-14	76.0	29XP9@1|root,30JEV@2|Bacteria,2HGER@201174|Actinobacteria,4CNCS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_1500278_3	1229780.BN381_110020	2.141e-108	362.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,3UXC9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158390_k127_1500278_8	1313172.YM304_37680	3.342e-72	266.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CN76@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158390_k127_1500278_9	525909.Afer_1913	1.863e-64	227.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CNRA@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158390_k127_1500278_1	269800.Tfu_2895	1.118e-223	714.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4EGHW@85012|Streptosporangiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158390_k127_1500278_7	1229780.BN381_110024	1.782e-80	273.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,3UWJV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158390_k127_1500278_6	1229780.BN381_110025	9.128e-82	281.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,3UWGD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,Pterin_bind
SRR25158390_k127_1500278_11	1229780.BN381_110026	1.36e-63	222.0	2F3QB@1|root,33WH4@2|Bacteria,2H50W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1502629_13	471852.Tcur_4489	0.0004488	47.0	COG3127@1|root,COG4591@1|root,COG3127@2|Bacteria,COG4591@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_1502629_11	1122609.AUGT01000020_gene1126	1.476e-10	71.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4DWWD@85009|Propionibacteriales	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_1502629_12	717605.Theco_2791	1.731e-10	75.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,26ZR6@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccB	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SRR25158390_k127_1502629_6	103733.JNYO01000016_gene3385	1.426e-57	229.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria,4E0XU@85010|Pseudonocardiales	201174|Actinobacteria	S	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
SRR25158390_k127_1502629_0	219305.MCAG_02552	2.151e-309	983.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158390_k127_1502629_9	494419.ALPM01000010_gene714	6.229e-31	126.0	COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria,1WA1U@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR25158390_k127_1502629_10	1249975.JQLP01000005_gene2115	1.4e-26	115.0	COG4319@1|root,COG4319@2|Bacteria,4NPRA@976|Bacteroidetes,1I2MN@117743|Flavobacteriia	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1502629_1	861299.J421_1936	8.701e-228	725.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158390_k127_1502629_5	1313172.YM304_07710	1.796e-90	320.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria	201174|Actinobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_1502629_3	1313172.YM304_07700	2.321e-111	374.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_1502629_4	1313172.YM304_07690	1.257e-98	337.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158390_k127_1502629_8	1380393.JHVP01000004_gene416	8.915e-32	130.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4ETBE@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1502629_2	298655.KI912267_gene6910	4.103e-149	490.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2GKXJ@201174|Actinobacteria,4ESTX@85013|Frankiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158390_k127_1502629_7	1151061.CAJY01000004_gene2241	1.103e-45	172.0	COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria	201174|Actinobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1531108_1	1048339.KB913029_gene3449	5.951e-159	510.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4ES8T@85013|Frankiales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_1531108_0	1229780.BN381_10094	5.475e-195	618.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,3UW72@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158390_k127_1531108_5	1463820.JOGW01000007_gene1837	7.561e-69	251.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158390_k127_1531108_6	861299.J421_3494	1.645e-63	243.0	COG2148@1|root,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	pglC	GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.36	ko:K15915,ko:K19428	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
SRR25158390_k127_1531108_4	322710.Avin_30060	5.339e-75	263.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,1S3R7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158390_k127_1531108_2	1229780.BN381_50026	3.323e-102	351.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1531108_7	1229780.BN381_50025	7.529e-58	211.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Polysacc_deac_1
SRR25158390_k127_1531108_3	1229780.BN381_490004	1.188e-85	296.0	COG3153@1|root,COG3153@2|Bacteria,2I8ZE@201174|Actinobacteria	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SRR25158390_k127_1531108_8	1123504.JQKD01000033_gene5265	1.09e-06	58.0	COG1073@1|root,COG1073@2|Bacteria,1N6XT@1224|Proteobacteria,2VUPI@28216|Betaproteobacteria,4AJCB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158390_k127_1532918_3	222534.KB893787_gene206	1.637e-50	186.0	COG0183@1|root,COG0183@2|Bacteria,2GKWR@201174|Actinobacteria,4ES3R@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_1532918_2	298653.Franean1_2697	4.481e-111	377.0	COG0683@1|root,COG0683@2|Bacteria,2IB96@201174|Actinobacteria	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_1532918_1	298654.FraEuI1c_5420	1.145e-115	402.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU9I@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_1532918_0	298654.FraEuI1c_4139	3.946e-242	783.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU9I@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_1532918_4	298654.FraEuI1c_4140	9.541e-37	160.0	COG0410@1|root,COG0410@2|Bacteria,2IH68@201174|Actinobacteria	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_1590039_1	1158050.KB895455_gene1715	2.572e-272	849.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria,1WB4P@1268|Micrococcaceae	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_1590039_8	258533.BN977_05885	7.013e-07	62.0	COG1247@1|root,COG1247@2|Bacteria,2I5P3@201174|Actinobacteria,23AE3@1762|Mycobacteriaceae	201174|Actinobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_1590039_0	557599.MKAN_04505	0.0	1023.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,2378B@1762|Mycobacteriaceae	201174|Actinobacteria	P	possibly catalyzes the transport of a undeterminated metal cation with the hydrolyse of ATP catalytic activity ATP H(2)O undeterminated metal cation(in) ADP phosphate undeterminated metal cation(out)	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158390_k127_1590039_6	298655.KI912266_gene2846	4.65e-31	128.0	COG2905@1|root,COG2905@2|Bacteria,2GVP5@201174|Actinobacteria,4EWMQ@85013|Frankiales	201174|Actinobacteria	T	CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF1918
SRR25158390_k127_1590039_4	570268.ANBB01000088_gene171	3.688e-45	176.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJD9@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1590039_3	436229.JOEH01000052_gene6310	1.214e-82	289.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,2NGHW@228398|Streptacidiphilus	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158390_k127_1590039_5	1146883.BLASA_1738	9.593e-35	140.0	2FHIX@1|root,349CW@2|Bacteria,2GN7H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1590039_2	1146883.BLASA_1739	2.834e-169	554.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_1594204_7	1313172.YM304_27700	1.735e-105	348.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CMXE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158390_k127_1594204_17	351607.Acel_1683	1.42e-44	171.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4ESQ0@85013|Frankiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158390_k127_1594204_0	351607.Acel_1394	0.0	1223.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158390_k127_1594204_19	298654.FraEuI1c_6869	1.785e-23	112.0	2FCKD@1|root,344PQ@2|Bacteria,2GVQX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1594204_1	1229780.BN381_450017	3.71e-196	635.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36N,Melibiase
SRR25158390_k127_1594204_5	1123023.JIAI01000002_gene4683	6.822e-122	400.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4E1C7@85010|Pseudonocardiales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158390_k127_1594204_20	518766.Rmar_1903	1.973e-07	57.0	COG0694@1|root,COG0694@2|Bacteria,4PEVI@976|Bacteroidetes,1FJPA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Scaffold protein Nfu/NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N
SRR25158390_k127_1594204_8	1254432.SCE1572_23945	4.637e-104	355.0	COG2159@1|root,COG2159@2|Bacteria,1PZGI@1224|Proteobacteria,435YS@68525|delta/epsilon subdivisions,2X9TW@28221|Deltaproteobacteria,2Z1SH@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158390_k127_1594204_13	298654.FraEuI1c_1951	4.182e-81	275.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4ES45@85013|Frankiales	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158390_k127_1594204_15	882083.SacmaDRAFT_2725	2.388e-71	248.0	2C3A2@1|root,2ZZP3@2|Bacteria,2I9BD@201174|Actinobacteria,4E3TD@85010|Pseudonocardiales	201174|Actinobacteria	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158390_k127_1594204_21	1449347.JQLN01000005_gene3345	0.0001065	51.0	2B751@1|root,3206I@2|Bacteria,2I1F1@201174|Actinobacteria,2M3R1@2063|Kitasatospora	201174|Actinobacteria	S	MT0933-like antitoxin protein	-	-	-	-	-	-	-	-	-	-	-	-	MT0933_antitox
SRR25158390_k127_1594204_11	1229780.BN381_80063	1.094e-97	325.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,3UWJU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158390_k127_1594204_3	1045009.AFXQ01000017_gene264	3.878e-150	486.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,1W8QY@1268|Micrococcaceae	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_1594204_18	35754.JNYJ01000014_gene4717	5.294e-31	134.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4DD1H@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1594204_16	1449976.KALB_4798	3.111e-58	226.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4E0A3@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR25158390_k127_1594204_12	1121926.AXWO01000004_gene956	9.102e-88	313.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4EZKW@85014|Glycomycetales	201174|Actinobacteria	S	KR domain	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR25158390_k127_1594204_10	326424.FRAAL0924	5.423e-100	350.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,4ETSB@85013|Frankiales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158390_k127_1594204_4	477641.MODMU_1857	1.052e-128	419.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4ESJ9@85013|Frankiales	201174|Actinobacteria	GM	epimerase dehydratase	galE4	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_1594204_14	1246995.AFR_16780	7.048e-80	272.0	COG1028@1|root,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4DCYR@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1594204_6	1121377.KB906405_gene135	1.888e-111	381.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158390_k127_1594204_2	1211815.CBYP010000067_gene115	1.538e-180	573.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE1_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1594204_9	414684.RC1_3591	1.565e-103	344.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,2JQUA@204441|Rhodospirillales	204441|Rhodospirillales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158390_k127_1597329_0	1380393.JHVP01000007_gene4388	1.713e-168	556.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EUE1@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	CarboxypepD_reg,MMPL
SRR25158390_k127_1597329_2	1521187.JPIM01000028_gene1594	5.367e-74	260.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_1597329_3	326427.Cagg_2708	6.869e-55	205.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_1597329_1	1313172.YM304_10790	1.892e-103	342.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4CMYM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_1597329_4	1313172.YM304_10780	1.83e-25	110.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CMYQ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158390_k127_1612591_12	1160718.SU9_31893	9.756e-18	84.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria	201174|Actinobacteria	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158390_k127_1612591_8	367299.JOEE01000001_gene1575	4.058e-36	147.0	2DMUS@1|root,32TTH@2|Bacteria,2I84Q@201174|Actinobacteria	201174|Actinobacteria	S	lycopene cyclase	crtYc	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1612591_6	1078020.KEK_04897	1.053e-41	158.0	2E9MI@1|root,333U6@2|Bacteria,2IMX9@201174|Actinobacteria,23A2U@1762|Mycobacteriaceae	201174|Actinobacteria	S	lycopene cyclase	crtYd	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1612591_3	1249627.D779_3029	4.858e-55	211.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,1SAEV@1236|Gammaproteobacteria,1WZQW@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1612591_9	1385518.N798_05420	6.68e-35	141.0	2E9V0@1|root,3340V@2|Bacteria,2GVC5@201174|Actinobacteria	201174|Actinobacteria	S	carotenoid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1612591_11	525909.Afer_0482	3.663e-32	130.0	COG3000@1|root,COG3000@2|Bacteria,2HG86@201174|Actinobacteria,4CN57@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Fatty acid hydroxylase superfamily	-	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
SRR25158390_k127_1612591_1	935261.JAGL01000010_gene1937	1.859e-126	417.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2TQMC@28211|Alphaproteobacteria,43GV4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	PrpF protein	fldA	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
SRR25158390_k127_1612591_2	1038866.KB902799_gene461	7.347e-109	365.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3JSFK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	MA20_26630	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158390_k127_1612591_4	1246995.AFR_00460	4.153e-50	193.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4D99Y@85008|Micromonosporales	201174|Actinobacteria	S	protein, hemolysin III	hlyI	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158390_k127_1612591_0	67373.JOBF01000002_gene1460	2.587e-154	513.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158390_k127_1612591_5	1449347.JQLN01000005_gene5103	3.008e-45	167.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,2M3I2@2063|Kitasatospora	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_1612591_7	1380346.JNIH01000011_gene2745	5.955e-40	150.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1612591_10	1120934.KB894403_gene195	1.139e-34	151.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4E225@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_165130_4	1313172.YM304_26370	1.916e-76	267.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4CNDA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
SRR25158390_k127_165130_0	1313172.YM304_26330	3.357e-114	395.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4CN2B@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
SRR25158390_k127_165130_3	1068980.ARVW01000001_gene1152	5.416e-82	284.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria,4DXKD@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158390_k127_165130_7	710111.FraQA3DRAFT_4212	1.625e-09	70.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	3.1.3.10	ko:K01085	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	Imm49,Peptidase_M15_3
SRR25158390_k127_165130_6	351160.RRC328	1.794e-22	108.0	COG4914@1|root,arCOG04119@2157|Archaea	2157|Archaea	S	PFAM Conserved Archaeal protein (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
SRR25158390_k127_165130_2	1206725.BAFU01000021_gene3423	4.276e-92	317.0	COG3186@1|root,COG3186@2|Bacteria,2GKCB@201174|Actinobacteria,4FVIU@85025|Nocardiaceae	201174|Actinobacteria	E	Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
SRR25158390_k127_165130_5	1179773.BN6_71440	4.504e-41	166.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4E4HQ@85010|Pseudonocardiales	201174|Actinobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158390_k127_165130_1	204669.Acid345_1786	1.183e-108	358.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia	204432|Acidobacteriia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158390_k127_1651787_4	1313172.YM304_04660	1.003e-52	191.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4CN4V@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158390_k127_1651787_3	1229780.BN381_150089	3.334e-74	268.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,3UWDZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158390_k127_1651787_5	35754.JNYJ01000007_gene2765	1.803e-39	161.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4D8RZ@85008|Micromonosporales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158390_k127_1651787_0	1137268.AZXF01000009_gene3911	5.043e-118	402.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4EGDH@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158390_k127_1651787_2	1229780.BN381_150091	1.317e-98	334.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,3UWQJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Glycerate kinase family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158390_k127_1651787_6	1229780.BN381_150094	2.202e-31	124.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,3UXHU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_1651787_1	525909.Afer_1846	5.24e-107	350.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158390_k127_1652382_2	1449353.JQMQ01000005_gene4428	0.0002798	43.0	2EQWD@1|root,33IG7@2|Bacteria,2GQNK@201174|Actinobacteria,2NK6Q@228398|Streptacidiphilus	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_1652382_0	1032480.MLP_49410	5.967e-168	541.0	28IM9@1|root,2Z8MS@2|Bacteria,2GIR6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1652382_1	219305.MCAG_03411	4.167e-126	420.0	COG1674@1|root,COG1674@2|Bacteria,2GJA3@201174|Actinobacteria,4DBJF@85008|Micromonosporales	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR25158390_k127_1653033_3	935866.JAER01000023_gene2275	7.894e-47	177.0	COG3324@1|root,COG3324@2|Bacteria,2I6WX@201174|Actinobacteria,4DUHF@85009|Propionibacteriales	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1653033_2	251229.Chro_4958	7.856e-60	237.0	KOG2524@1|root,2ZJ84@2|Bacteria	2|Bacteria	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
SRR25158390_k127_1653033_0	886293.Sinac_5044	4.071e-147	492.0	COG1505@1|root,COG1505@2|Bacteria,2IXRJ@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158390_k127_1653033_4	1323361.JPOC01000006_gene672	6.639e-35	144.0	2EUVM@1|root,33NB3@2|Bacteria,2GTGH@201174|Actinobacteria,4G0N0@85025|Nocardiaceae	201174|Actinobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158390_k127_1653033_5	936136.ARRT01000002_gene575	2.693e-09	62.0	2BD51@1|root,326SN@2|Bacteria,1R205@1224|Proteobacteria,2TZ86@28211|Alphaproteobacteria,4BDTR@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1668148_24	1171373.PACID_13110	2.416e-28	115.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN4J@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158390_k127_1668148_4	1229780.BN381_410040	2.776e-169	539.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,3UWB7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158390_k127_1668148_1	1313172.YM304_21620	1.89e-281	882.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CMVA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
SRR25158390_k127_1668148_20	1313172.YM304_21650	3.592e-75	273.0	COG0500@1|root,COG2226@2|Bacteria,2HG5Z@201174|Actinobacteria,4CN2W@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_1668148_19	351607.Acel_1111	3.962e-84	295.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4EREI@85013|Frankiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158390_k127_1668148_22	1229780.BN381_80400	1.045e-59	219.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,3UXFA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158390_k127_1668148_5	1229780.BN381_80401	4.276e-160	510.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,3UW79@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158390_k127_1668148_3	1229780.BN381_80402	1.364e-174	572.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,3UWA2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158390_k127_1668148_14	1313172.YM304_21690	1.001e-97	334.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CMZ0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158390_k127_1668148_6	2002.JOEQ01000016_gene7360	2.912e-150	497.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_1668148_10	2002.JOEQ01000016_gene7361	1.066e-118	389.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_1668148_17	330084.JNYZ01000044_gene1991	6.138e-93	326.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4DYJ1@85010|Pseudonocardiales	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_1668148_12	479433.Caci_7776	6.73e-112	382.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1668148_7	479432.Sros_7207	7.516e-131	428.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EM7U@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1668148_26	1229780.BN381_80404	1.369e-17	85.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,3UWW8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158390_k127_1668148_2	526225.Gobs_4665	2.293e-271	855.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4ERST@85013|Frankiales	201174|Actinobacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	cutL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_1668148_21	1089545.KB913037_gene597	4.125e-69	239.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E49V@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158390_k127_1668148_0	525909.Afer_1569	0.0	1145.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CMWW@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_1668148_15	28042.GU90_16810	1.411e-97	350.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4E0PT@85010|Pseudonocardiales	201174|Actinobacteria	C	carbon monoxide dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158390_k127_1668148_18	1120949.KB903326_gene3159	8.038e-90	309.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1668148_13	1869.MB27_11130	3.166e-105	346.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DH4A@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_1668148_8	710687.KI912270_gene4527	1.444e-129	432.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,23FHB@1762|Mycobacteriaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_1668148_25	1123024.AUII01000006_gene4641	3.36e-19	91.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158390_k127_1668148_9	1313172.YM304_33360	1.167e-119	391.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CMRT@84992|Acidimicrobiia	84992|Acidimicrobiia	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158390_k127_1668148_11	1313172.YM304_33370	1.497e-113	377.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CNNX@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158390_k127_1668148_23	1306174.JODP01000006_gene3139	3.711e-37	143.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158390_k127_1668148_16	1313172.YM304_33390	1.058e-93	317.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4CN04@84992|Acidimicrobiia	84992|Acidimicrobiia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158390_k127_1690774_2	1089550.ATTH01000001_gene1477	2.827e-26	124.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
SRR25158390_k127_1690774_1	525368.HMPREF0591_1972	1.193e-32	140.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,234WK@1762|Mycobacteriaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005504,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031406,GO:0033293,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158390_k127_1690774_0	1205680.CAKO01000002_gene2489	1.786e-53	191.0	COG2159@1|root,COG2159@2|Bacteria,1P6G6@1224|Proteobacteria,2TU10@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_1812984_4	1206726.BAFV01000057_gene4197	9.117e-94	317.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria,4FWTM@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_1812984_6	247156.NFA_47870	1.094e-57	218.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4G2AF@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1812984_1	1394178.AWOO02000034_gene8341	1.171e-152	497.0	COG2141@1|root,COG3255@1|root,COG2141@2|Bacteria,COG3255@2|Bacteria,2GKP1@201174|Actinobacteria,4EHH5@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase,SCP2
SRR25158390_k127_1812984_8	1333998.M2A_2494	1.177e-48	193.0	2EXDM@1|root,33QQ7@2|Bacteria,1NTQ6@1224|Proteobacteria,2UQVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1812984_0	1229780.BN381_430065	9.405e-225	720.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,3UWA8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158390_k127_1812984_2	1041522.MCOL_V201895	2.094e-110	367.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,232K1@1762|Mycobacteriaceae	201174|Actinobacteria	S	NADP-dependent oxidoreductase	yfmJ	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRR25158390_k127_1812984_7	1313172.YM304_19640	1.532e-57	208.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4CN7W@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_1812984_3	1229780.BN381_430072	2.813e-108	361.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,3UWBK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA polymerase alpha chain like domain	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158390_k127_1831478_2	196627.cg2188	3.256e-83	292.0	COG1239@1|root,COG1239@2|Bacteria,2GN3S@201174|Actinobacteria,22JIU@1653|Corynebacteriaceae	201174|Actinobacteria	H	Mg-chelatase subunit ChlI	chlI	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
SRR25158390_k127_1831478_0	1229780.BN381_130289	1.475e-107	357.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,3UWI0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158390_k127_1831478_4	1122138.AQUZ01000073_gene4428	1.4e-58	214.0	COG1576@1|root,COG3631@1|root,COG1576@2|Bacteria,COG3631@2|Bacteria,2IGAN@201174|Actinobacteria,4DVE4@85009|Propionibacteriales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_1831478_5	1255043.TVNIR_1089	5.323e-16	79.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,1SJ4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158390_k127_1831478_1	1041522.MCOL_V211355	1.567e-105	366.0	COG1960@1|root,COG1960@2|Bacteria,2IAIE@201174|Actinobacteria,237ZZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE35	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158390_k127_1831478_6	479435.Kfla_0244	5.222e-13	69.0	2EK8X@1|root,33DZ6@2|Bacteria,2GWJW@201174|Actinobacteria,4DSK4@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1831478_3	944435.AXAJ01000007_gene1660	3.507e-67	249.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_4,zinc_ribbon_2
SRR25158390_k127_1834755_4	1206733.BAGC01000062_gene3465	1.802e-07	53.0	COG0411@1|root,COG0411@2|Bacteria,2I5YM@201174|Actinobacteria,4FZP7@85025|Nocardiaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_1834755_0	1449976.KALB_3114	5.631e-236	750.0	COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria,4EE39@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158390_k127_1834755_1	345341.KUTG_08194	1.299e-230	730.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_1834755_3	1229780.BN381_130040	1.299e-39	160.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,3UWZK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_1834755_2	1382356.JQMP01000003_gene1431	3.03e-87	291.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_184208_17	426716.JOAJ01000001_gene1267	2.251e-09	59.0	COG1752@1|root,COG1752@2|Bacteria,2IFBM@201174|Actinobacteria,4FWBX@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_184208_1	477641.MODMU_1882	1.7e-193	625.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4ETWS@85013|Frankiales	201174|Actinobacteria	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158390_k127_184208_0	1095767.CAHD01000194_gene207	2.209e-214	674.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4F0NA@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM glutamine synthetase catalytic region	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_184208_2	1313172.YM304_38340	6.983e-191	605.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CMV7@84992|Acidimicrobiia	84992|Acidimicrobiia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_184208_8	1313172.YM304_38350	7.523e-89	299.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CN27@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158390_k127_184208_10	1169152.AXVD01000014_gene1496	1.483e-71	246.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4G185@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_184208_5	101510.RHA1_ro01743	7.43e-163	522.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,4FW2I@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158390_k127_184208_14	1313172.YM304_38390	9.23e-32	128.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_184208_4	1313172.YM304_38400	6.131e-166	544.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	xdh	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158390_k127_184208_3	35754.JNYJ01000046_gene3102	1.68e-174	563.0	COG1520@1|root,COG1520@2|Bacteria,2I9S4@201174|Actinobacteria,4D97G@85008|Micromonosporales	201174|Actinobacteria	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158390_k127_184208_13	1121877.JQKF01000018_gene2552	2.16e-32	140.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CN53@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Iron-sulphur cluster biosynthesis	erpA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158390_k127_184208_11	1313172.YM304_38450	1.244e-66	234.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_184208_6	1313172.YM304_38460	1.92e-127	423.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2H1YI@201174|Actinobacteria,4CNPI@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158390_k127_184208_12	471852.Tcur_1157	2.212e-33	138.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4EP7I@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_184208_9	83406.HDN1F_14020	2.609e-76	265.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0491 Zn-dependent hydrolases, including glyoxylases	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
SRR25158390_k127_184208_16	1229780.BN381_400015	2.499e-22	102.0	COG3030@1|root,COG3030@2|Bacteria	2|Bacteria	S	protein affecting phage T7 exclusion by the F plasmid	fxsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	2.3.3.13	ko:K01649,ko:K07113	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	FxsA
SRR25158390_k127_184208_15	1229780.BN381_100117	6.624e-30	122.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_184208_7	1229780.BN381_100118	1.432e-89	311.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07340,ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,LprI,NfeD,SDH_sah
SRR25158390_k127_184208_21	1229780.BN381_100119	0.0001674	47.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,3UXHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_184471_6	996637.SGM_2948	1.046e-81	276.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	ehuA	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158390_k127_184471_5	1211815.CBYP010000042_gene2406	1.42e-96	334.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158390_k127_184471_0	1123023.JIAI01000001_gene6484	1.077e-264	827.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DZQU@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158390_k127_184471_7	1150864.MILUP08_40568	4.664e-71	256.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4D8GP@85008|Micromonosporales	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158390_k127_184471_11	37919.EP51_02835	5.241e-37	154.0	COG1957@1|root,COG1957@2|Bacteria,2IGI6@201174|Actinobacteria,4G5N0@85025|Nocardiaceae	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158390_k127_184471_9	1380356.JNIK01000005_gene892	9.246e-70	262.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158390_k127_184471_4	266117.Rxyl_3023	1.014e-100	342.0	COG1171@1|root,COG1171@2|Bacteria,2I8ZW@201174|Actinobacteria,4CQ5T@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
SRR25158390_k127_184471_10	222534.KB893731_gene6057	5.878e-64	228.0	COG0655@1|root,COG0655@2|Bacteria,2II43@201174|Actinobacteria,4ESWD@85013|Frankiales	201174|Actinobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158390_k127_184471_1	402881.Plav_2680	3.098e-217	688.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158390_k127_184471_3	1229780.BN381_130222	4.595e-125	416.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_184471_2	1229780.BN381_130221	1.11e-195	619.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_184471_8	487521.OCU_45760	7.476e-70	266.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,236G4@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158390_k127_1854901_1	1229780.BN381_70018	1.826e-86	297.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,3UWBG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell cycle protein	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158390_k127_1854901_2	1229780.BN381_70017	5.55e-79	287.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,3UWNU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158390_k127_1854901_7	1229780.BN381_70016	3.627e-37	146.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,3UWWG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Forkhead associated domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158390_k127_1854901_3	1229780.BN381_70015	9.68e-64	240.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,3UWPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158390_k127_1854901_0	1380347.JNII01000006_gene1240	1.934e-102	347.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4ERYV@85013|Frankiales	201174|Actinobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158390_k127_1854901_4	679197.HMPREF9336_01143	3.084e-62	222.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
SRR25158390_k127_1854901_6	1394178.AWOO02000013_gene7962	9.81e-38	155.0	COG0789@1|root,COG0789@2|Bacteria,2I8PU@201174|Actinobacteria,4EJGP@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_1854901_5	1298880.AUEV01000013_gene3915	5.557e-58	212.0	29RNN@1|root,30CRY@2|Bacteria,2GKXM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_1922700_2	1313172.YM304_23250	3.053e-43	171.0	COG0730@1|root,COG0730@2|Bacteria,2HGFT@201174|Actinobacteria,4CNDC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_1922700_0	561175.KB894102_gene1115	3.272e-192	613.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4EH9W@85012|Streptosporangiales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158390_k127_1922700_5	710696.Intca_1762	0.0001347	51.0	COG1994@1|root,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4FGTA@85021|Intrasporangiaceae	201174|Actinobacteria	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR25158390_k127_1922700_1	1242864.D187_003477	3.123e-148	493.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein 2	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158390_k127_1922700_4	1304865.JAGF01000001_gene970	2.514e-05	51.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria	201174|Actinobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158390_k127_1927744_3	2074.JNYD01000001_gene5846	3.932e-86	310.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2H57H@201174|Actinobacteria,4EF5W@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158390_k127_1927744_5	296591.Bpro_0276	2.614e-68	240.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2VKQ8@28216|Betaproteobacteria,4AFYK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_1927744_8	479431.Namu_4940	6.248e-48	177.0	COG0607@1|root,COG0607@2|Bacteria,2IKTC@201174|Actinobacteria,4ET2W@85013|Frankiales	201174|Actinobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158390_k127_1927744_13	1348657.M622_00300	2.203e-13	77.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,2WGPE@28216|Betaproteobacteria,2KXA4@206389|Rhodocyclales	206389|Rhodocyclales	G	Cupin domain	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
SRR25158390_k127_1927744_11	1246448.ANAZ01000033_gene5650	1.923e-42	167.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4EJN6@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158390_k127_1927744_7	479434.Sthe_0109	5.43e-53	194.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_1927744_1	1229780.BN381_50178	1.061e-92	313.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,3UWK3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158390_k127_1927744_0	1229780.BN381_50177	2.585e-197	625.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,3UWAH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_1927744_4	1313172.YM304_24300	4.034e-76	261.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CN2A@84992|Acidimicrobiia	84992|Acidimicrobiia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158390_k127_1927744_2	1313172.YM304_24270	1.979e-89	301.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CN2P@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158390_k127_1927744_12	1132441.KI519454_gene2219	3.758e-15	82.0	COG0484@1|root,COG0484@2|Bacteria,2IDAA@201174|Actinobacteria,1W86U@1268|Micrococcaceae	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158390_k127_1927744_10	1229780.BN381_80382	9.743e-43	176.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,3UX0E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158390_k127_1927744_9	1032480.MLP_32670	1.821e-43	171.0	COG3173@1|root,COG3173@2|Bacteria,2GKUE@201174|Actinobacteria,4DRUD@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1927744_6	1313172.YM304_22710	2.488e-60	211.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CMW2@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158390_k127_1978868_8	1313172.YM304_25510	2.9e-13	69.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CNFE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1978868_6	1123319.AUBE01000007_gene3738	1.629e-45	183.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1978868_3	1229780.BN381_80127	4.195e-108	356.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,3UXC4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	KR domain	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158390_k127_1978868_0	471852.Tcur_1862	5.218e-247	778.0	COG0511@1|root,COG4799@1|root,COG0511@2|Bacteria,COG4799@2|Bacteria,2I46V@201174|Actinobacteria	201174|Actinobacteria	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl,Carboxyl_trans
SRR25158390_k127_1978868_4	479432.Sros_0349	3.04e-64	233.0	COG0346@1|root,COG0346@2|Bacteria,2IK75@201174|Actinobacteria,4ENKU@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1978868_5	298654.FraEuI1c_3818	6.028e-55	198.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_1978868_2	1961.JOAK01000014_gene5640	6.751e-138	453.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_1978868_7	479432.Sros_8868	1.228e-23	118.0	COG1309@1|root,COG1309@2|Bacteria,2H131@201174|Actinobacteria,4EQC9@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_1978868_1	1449353.JQMQ01000005_gene5848	9.974e-186	610.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,2NF1H@228398|Streptacidiphilus	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD19	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_1978868_9	1449353.JQMQ01000004_gene5915	9.916e-07	59.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,2NHPN@228398|Streptacidiphilus	201174|Actinobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158390_k127_1987239_3	1048339.KB913029_gene1150	5.952e-50	180.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_1987239_1	1121926.AXWO01000008_gene2922	4.457e-79	284.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria,4EZPS@85014|Glycomycetales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158390_k127_1987239_0	644283.Micau_5428	4.152e-135	464.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4D8HC@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158390_k127_1987239_6	479431.Namu_0399	5.931e-13	76.0	COG2323@1|root,COG2323@2|Bacteria,2IK7N@201174|Actinobacteria,4ETKC@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158390_k127_1987239_2	1120950.KB892708_gene4507	1.155e-53	198.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria,4DUVR@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158390_k127_1987239_5	1265310.CCBD010000069_gene466	8.259e-22	100.0	2BG9C@1|root,32A6J@2|Bacteria,2GPNJ@201174|Actinobacteria,23AWE@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1987239_4	749414.SBI_00971	4.076e-47	174.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_1994278_9	1206737.BAGF01000056_gene3475	3.297e-66	231.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4FVWD@85025|Nocardiaceae	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158390_k127_1994278_19	1304865.JAGF01000001_gene3334	1.472e-16	89.0	2CF3M@1|root,330XH@2|Bacteria,2GUUV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1994278_13	330084.JNYZ01000044_gene1963	1.183e-37	150.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4E3X2@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_1994278_15	1266908.AQPB01000039_gene832	1.772e-33	142.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_1994278_11	110319.CF8_4080	2.58e-49	183.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4DNET@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158390_k127_1994278_17	1032480.MLP_52270	2.905e-28	120.0	COG0640@1|root,COG0640@2|Bacteria,2IMDE@201174|Actinobacteria,4DVCI@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21885	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1994278_1	1120950.KB892759_gene6244	4.218e-115	374.0	COG0262@1|root,COG0262@2|Bacteria,2HG3J@201174|Actinobacteria,4DVCB@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_1994278_18	1380394.JADL01000001_gene2170	7.676e-27	121.0	COG0346@1|root,COG0346@2|Bacteria,1NFR3@1224|Proteobacteria,2UMIM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1994278_5	1382303.JPOM01000001_gene2362	3.108e-81	278.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,2U1W2@28211|Alphaproteobacteria,2KHXP@204458|Caulobacterales	204458|Caulobacterales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158390_k127_1994278_10	648757.Rvan_1770	3.739e-58	231.0	2FG7J@1|root,3483Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1994278_12	1313172.YM304_40930	6.431e-42	179.0	2ED9D@1|root,3375U@2|Bacteria,2H989@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1994278_8	1123253.AUBD01000005_gene242	4.342e-72	254.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria,1X81A@135614|Xanthomonadales	135614|Xanthomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1994278_4	1123023.JIAI01000001_gene6343	8.037e-87	295.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4E3Q3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1994278_2	1123023.JIAI01000001_gene6342	2.418e-100	336.0	COG1396@1|root,COG1396@2|Bacteria,2GKRR@201174|Actinobacteria,4E89B@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158390_k127_1994278_16	525373.HMPREF0766_12944	1.094e-29	127.0	COG3631@1|root,COG3631@2|Bacteria,4NTMZ@976|Bacteroidetes,1IZ30@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158390_k127_1994278_3	1089545.KB913037_gene3459	5.812e-96	350.0	COG3012@1|root,COG3012@2|Bacteria,2GMRR@201174|Actinobacteria	201174|Actinobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158390_k127_1994278_20	208444.JNYY01000002_gene1324	1.819e-05	59.0	COG4451@1|root,COG4451@2|Bacteria,2I5D7@201174|Actinobacteria,4E6R6@85010|Pseudonocardiales	201174|Actinobacteria	C	ribulose bisphosphate carboxylase, small	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
SRR25158390_k127_1994278_7	710111.FraQA3DRAFT_4482	1.491e-73	265.0	COG4924@1|root,COG4924@2|Bacteria,2GNHY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
SRR25158390_k127_1994278_6	710111.FraQA3DRAFT_4481	5.745e-81	289.0	28HUD@1|root,2Z813@2|Bacteria,2ICFF@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397,DUF2398
SRR25158390_k127_1994278_0	710111.FraQA3DRAFT_4480	1.614e-144	482.0	2CC51@1|root,2Z7IU@2|Bacteria,2GM14@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
SRR25158390_k127_1994278_14	710111.FraQA3DRAFT_4479	1.043e-33	131.0	COG1196@1|root,COG1196@2|Bacteria,2GK6F@201174|Actinobacteria	201174|Actinobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR25158390_k127_20219_4	1313172.YM304_26410	3.618e-85	287.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158390_k127_20219_6	469383.Cwoe_1560	1.155e-21	109.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158390_k127_20219_7	861299.J421_2367	3.308e-16	89.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_20219_0	1121877.JQKF01000045_gene1208	7.896e-213	687.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CMU8@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158390_k127_20219_2	1313172.YM304_19970	6.724e-140	456.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CNBR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
SRR25158390_k127_20219_3	1146883.BLASA_4061	1.174e-85	293.0	COG1409@1|root,COG1409@2|Bacteria,2GP0C@201174|Actinobacteria,4EX0J@85013|Frankiales	201174|Actinobacteria	S	Purple acid Phosphatase, N-terminal domain	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
SRR25158390_k127_20219_8	1196029.ALIM01000002_gene4395	6.33e-07	58.0	COG0490@1|root,COG0490@2|Bacteria,1V544@1239|Firmicutes,4HIGC@91061|Bacilli,1ZR77@1386|Bacillus	91061|Bacilli	P	regulatory, ligand-binding protein related to C-terminal domains of K channels	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158390_k127_20219_1	243231.GSU1203	1.024e-152	499.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
SRR25158390_k127_20219_5	448385.sce7481	1.008e-30	138.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SRR25158390_k127_2026824_2	710685.MycrhN_6189	3.076e-125	406.0	COG1960@1|root,COG1960@2|Bacteria,2IBE0@201174|Actinobacteria,23EV2@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2026824_0	298655.KI912266_gene5765	1.002e-155	519.0	COG0318@1|root,COG0318@2|Bacteria,2IBED@201174|Actinobacteria,4EU08@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2026824_3	1380356.JNIK01000003_gene1261	1.772e-97	328.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4EX2F@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2026824_4	1265310.CCBD010000015_gene3714	1.155e-55	203.0	COG4221@1|root,COG4221@2|Bacteria,2IFSP@201174|Actinobacteria,23966@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2026824_7	1219045.BV98_001303	2.838e-05	55.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2KA6D@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158390_k127_2026824_1	298655.KI912266_gene3866	5.06e-138	451.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria,4EX8Y@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_2026824_6	298655.KI912266_gene5044	1.777e-07	56.0	COG1309@1|root,COG1309@2|Bacteria,2IDYQ@201174|Actinobacteria	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_2056432_5	1121926.AXWO01000008_gene2923	4.797e-46	171.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EZPK@85014|Glycomycetales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2056432_2	1045009.AFXQ01000014_gene541	6.399e-62	224.0	COG2267@1|root,COG2267@2|Bacteria,2GMBV@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2056432_4	331869.BAL199_28925	1.014e-47	177.0	COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,4BT3J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent enzyme of the double-stranded beta helix superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2056432_3	1906.SFRA_05145	1.905e-55	201.0	COG3153@1|root,COG3153@2|Bacteria,2IKX0@201174|Actinobacteria	201174|Actinobacteria	Q	acetyltransferase	-	-	-	ko:K03824,ko:K09964	-	-	-	-	ko00000,ko01000	-	-	-	ACT_3,ACT_7,Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
SRR25158390_k127_2056432_7	1132441.KI519454_gene1477	1.241e-13	75.0	2DQPU@1|root,337ZH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2056432_0	479432.Sros_9341	6.252e-142	457.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4EGPW@85012|Streptosporangiales	201174|Actinobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158390_k127_2056432_1	1121385.AQXW01000003_gene471	5.867e-92	312.0	COG0702@1|root,COG0702@2|Bacteria,2GK71@201174|Actinobacteria,1ZWB2@145357|Dermacoccaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158390_k127_2056432_6	551789.ATVJ01000001_gene1325	3.834e-25	114.0	2DMXI@1|root,32U9G@2|Bacteria,1R4N1@1224|Proteobacteria,2U3EE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2077232_16	471852.Tcur_1812	3.068e-72	247.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria,4EJ8A@85012|Streptosporangiales	201174|Actinobacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158390_k127_2077232_19	1144275.COCOR_00183	9.834e-53	201.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,42XM7@68525|delta/epsilon subdivisions,2WSTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_2077232_20	1313172.YM304_19740	1.625e-52	193.0	2F9Q3@1|root,34209@2|Bacteria,2H616@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2077232_21	1313172.YM304_19730	4.544e-52	201.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CN4U@84992|Acidimicrobiia	84992|Acidimicrobiia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158390_k127_2077232_2	1120950.KB892708_gene4256	9.219e-234	741.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4DN38@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158390_k127_2077232_3	1229780.BN381_50169	4.884e-181	573.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,3UX20@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
SRR25158390_k127_2077232_14	1229780.BN381_50168	1.019e-83	285.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158390_k127_2077232_13	1445613.JALM01000006_gene562	1.72e-84	291.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DY0S@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type molybdenum transport system, ATPase component photorepair protein PhrA	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158390_k127_2077232_23	1229780.BN381_290139	1.242e-36	154.0	2FJAX@1|root,34B0V@2|Bacteria,2H7B1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2077232_25	926550.CLDAP_15510	2.547e-26	117.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158390_k127_2077232_26	929712.KI912613_gene711	3.657e-25	119.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158390_k127_2077232_4	1229780.BN381_210110	2.267e-175	564.0	COG1960@1|root,COG1960@2|Bacteria,2HY6H@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE21	-	-	ko:K00257	-	-	R04547,R04592	RC01942	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2077232_18	1121877.JQKF01000035_gene1966	5.088e-54	211.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CN2D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158390_k127_2077232_8	247633.GP2143_09295	2.2e-122	412.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1J6AR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_2077232_5	1229780.BN381_430028	5.55e-141	473.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,3UWER@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158390_k127_2077232_6	526226.Gbro_0408	4.357e-136	447.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4GA43@85026|Gordoniaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_2077232_10	258052.JNYV01000002_gene1542	3.305e-112	405.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,2M0JG@2063|Kitasatospora	201174|Actinobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158390_k127_2077232_29	101510.RHA1_ro03401	2.338e-11	72.0	2E62U@1|root,330RX@2|Bacteria,2GTSM@201174|Actinobacteria,4G72W@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2077232_22	1313172.YM304_22270	3.176e-49	182.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_2077232_0	1313172.YM304_22260	3.967e-321	1013.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
SRR25158390_k127_2077232_12	656024.FsymDg_2369	1.885e-85	320.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,4EWHX@85013|Frankiales	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_2077232_1	1121877.JQKF01000015_gene84	2.093e-234	735.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4CMV3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158390_k127_2077232_15	1313172.YM304_22230	2.202e-78	286.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4CN1J@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158390_k127_2077232_28	566461.SSFG_00273	3.197e-15	86.0	2BTY3@1|root,32P6C@2|Bacteria,2I8RQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_2077232_24	68570.DC74_7590	5.829e-34	149.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_2077232_27	926564.KI911740_gene3526	1.102e-18	100.0	2FEXV@1|root,346WK@2|Bacteria,2GVWC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2077232_17	926564.KI911740_gene3527	3.238e-61	221.0	2C30W@1|root,33T8Q@2|Bacteria,2H1UH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158390_k127_2077232_7	1313172.YM304_25250	1.392e-123	414.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria	201174|Actinobacteria	E	Oxidoreductase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
SRR25158390_k127_2077232_11	1173028.ANKO01000193_gene5879	1.594e-93	319.0	COG0451@1|root,COG0451@2|Bacteria,1G3T6@1117|Cyanobacteria,1HA43@1150|Oscillatoriales	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_2077232_9	1313172.YM304_25230	1.525e-114	403.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria	201174|Actinobacteria	M	3-beta hydroxysteroid dehydrogenase isomerase	-	-	-	ko:K21793	ko00333,ko01130,map00333,map01130	M00838	R11663,R11666	-	ko00000,ko00001,ko00002	-	-	-	Epimerase
SRR25158390_k127_2082441_8	223184.AS25_05020	2.201e-40	156.0	COG4244@1|root,COG4244@2|Bacteria,2I2FH@201174|Actinobacteria,1WCD7@1268|Micrococcaceae	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158390_k127_2082441_6	58123.JOFJ01000006_gene321	1.85e-55	203.0	COG0566@1|root,COG0566@2|Bacteria,2IEGA@201174|Actinobacteria,4EGKK@85012|Streptosporangiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	-	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158390_k127_2082441_3	469371.Tbis_1798	4.029e-75	261.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4E5AG@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
SRR25158390_k127_2082441_5	1229780.BN381_50154	2.538e-63	222.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,3UWS7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158390_k127_2082441_2	1313172.YM304_20570	4.299e-81	280.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CN6M@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formyl transferase, C-terminal domain	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158390_k127_2082441_1	1313172.YM304_20580	2.379e-108	364.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158390_k127_2082441_7	1121877.JQKF01000023_gene2242	1.108e-52	191.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CN1Q@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158390_k127_2082441_0	1229780.BN381_50158	3.421e-120	406.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,3UWIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158390_k127_2082441_4	1229780.BN381_50159	3.347e-71	244.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,3UWNT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158390_k127_2082441_9	1122218.KB893653_gene1170	5.434e-21	94.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,1JR9A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158390_k127_2126592_7	525909.Afer_1748	9.668e-16	79.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CNBI@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2126592_0	1380354.JIAN01000001_gene3647	5.691e-101	342.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158390_k127_2126592_2	525909.Afer_0742	2.56e-70	251.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4CN35@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2126592_5	1340493.JNIF01000003_gene1962	7.587e-37	157.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158390_k127_2126592_1	326427.Cagg_2454	1.147e-90	309.0	COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158390_k127_2126592_3	1280681.AUJZ01000024_gene3602	9.287e-64	239.0	COG0438@1|root,COG0438@2|Bacteria,1TQRV@1239|Firmicutes,24E7I@186801|Clostridia,4BYRD@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158390_k127_2126592_4	1235835.C814_02338	7.901e-47	193.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_2
SRR25158390_k127_2126592_6	1121428.DESHY_110327___1	1.98e-22	100.0	COG4122@1|root,COG4122@2|Bacteria,1VDR8@1239|Firmicutes	1239|Firmicutes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158390_k127_2134722_0	1229780.BN381_450030	3.646e-257	818.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,3UW8G@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158390_k127_2134722_2	1229780.BN381_80129	7.57e-212	674.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,3UWCG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158390_k127_2134722_3	479434.Sthe_1357	3.135e-198	649.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,27YSI@189775|Thermomicrobia	189775|Thermomicrobia	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158390_k127_2134722_4	1463845.JOIG01000009_gene3115	2.617e-187	595.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_2134722_5	1229780.BN381_80054	8.826e-154	494.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,3UWA9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158390_k127_2134722_6	543632.JOJL01000004_gene4116	8.55e-108	361.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2134722_1	1229780.BN381_80051	1.23e-212	676.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,3UWG3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2134722_7	1229780.BN381_40095	3.116e-98	333.0	COG1680@1|root,COG1680@2|Bacteria,2HQYW@201174|Actinobacteria,3UXP0@52018|unclassified Actinobacteria (class)	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_2136469_7	675635.Psed_5853	3.203e-07	51.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4E1N9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase, IS111A IS1328 IS1533, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_2136469_3	1229780.BN381_410015	4.535e-62	220.0	COG0045@1|root,COG0045@2|Bacteria,2I3K9@201174|Actinobacteria	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
SRR25158390_k127_2136469_4	1313172.YM304_26220	1.015e-59	213.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_2136469_2	1121877.JQKF01000007_gene981	3.573e-70	245.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158390_k127_2136469_1	330214.NIDE0322	6.702e-85	295.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158390_k127_2136469_0	1229780.BN381_410021	9.963e-240	757.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,3UW9I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158390_k127_2136469_5	1120949.KB903294_gene3987	3.009e-38	164.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4D9UT@85008|Micromonosporales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158390_k127_2138584_9	525909.Afer_0767	6.779e-29	122.0	COG1792@1|root,COG1792@2|Bacteria,2HGG4@201174|Actinobacteria,4CNDF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158390_k127_2138584_10	1229780.BN381_80097	2.414e-08	62.0	COG2891@1|root,COG2891@2|Bacteria	2|Bacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158390_k127_2138584_1	1229780.BN381_80098	1.848e-127	438.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,3UXBI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
SRR25158390_k127_2138584_3	1229780.BN381_80099	1.077e-88	309.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,3UX8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell cycle protein	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158390_k127_2138584_7	1095767.CAHD01000163_gene2999	4.59e-43	170.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158390_k127_2138584_2	1229780.BN381_330027	1.874e-100	338.0	COG0463@1|root,COG0463@2|Bacteria,2I3C0@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158390_k127_2138584_5	1229780.BN381_330025	8.223e-52	203.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158390_k127_2138584_6	1229780.BN381_330028	9.943e-46	188.0	28TMQ@1|root,2ZFV9@2|Bacteria,2GWN1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2138584_0	1229780.BN381_80100	2.144e-308	957.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,3UX71@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_2138584_4	1229780.BN381_80101	7.847e-53	201.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,3UXQA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158390_k127_2138584_8	1313172.YM304_18440	1.202e-42	169.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CMPW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribonuclease E/G family	-	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR25158390_k127_2150100_4	1229780.BN381_80311	9.676e-119	388.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,3UW96@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158390_k127_2150100_10	235985.BBPN01000038_gene540	1.626e-17	89.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria,2NI5K@228398|Streptacidiphilus	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158390_k127_2150100_3	1469245.JFBG01000054_gene2100	1.946e-149	484.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1T236@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158390_k127_2150100_8	1229780.BN381_80304	2.823e-42	162.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,3UWWX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_2150100_2	1229780.BN381_80303	5.294e-165	536.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,3UX86@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158390_k127_2150100_11	749927.AMED_1362	1.521e-16	87.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4E5MF@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158390_k127_2150100_1	1229780.BN381_80302	1.861e-210	684.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,3UW6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158390_k127_2150100_7	1229780.BN381_90081	6.508e-76	263.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,3UWHS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158390_k127_2150100_0	1313172.YM304_16400	1.54e-219	694.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CMS5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Zn-dependent metallo-hydrolase RNA specificity domain	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158390_k127_2150100_6	243365.CV_2048	6.171e-92	321.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KPQN@206351|Neisseriales	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158390_k127_2150100_9	1223523.H340_06466	1.478e-40	167.0	2B34Q@1|root,31VSF@2|Bacteria,2I9DC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2150100_5	1229780.BN381_80295	6.89e-108	352.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158390_k127_2156192_4	1120936.KB907208_gene1207	2.596e-45	171.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2156192_6	1123024.AUII01000050_gene633	4.144e-05	52.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158390_k127_2156192_0	298654.FraEuI1c_3933	2.33e-156	526.0	COG4591@1|root,COG4591@2|Bacteria,2I445@201174|Actinobacteria	201174|Actinobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_2156192_3	298655.KI912266_gene3162	1.141e-45	172.0	COG4591@1|root,COG4591@2|Bacteria,2I445@201174|Actinobacteria	201174|Actinobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_2156192_1	543632.JOJL01000007_gene5544	1.286e-111	365.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4DAEI@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2156192_2	35754.JNYJ01000024_gene9064	1.677e-84	284.0	COG1695@1|root,COG1695@2|Bacteria,2IH28@201174|Actinobacteria,4DI31@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_2156192_7	1869.MB27_31830	9.659e-05	51.0	COG3547@1|root,COG3547@2|Bacteria,2IDDB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3512a	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_2156192_5	469383.Cwoe_1126	1.261e-18	92.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJIA@201174|Actinobacteria,4CRFK@84995|Rubrobacteria	84995|Rubrobacteria	K	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_2173632_11	1229780.BN381_100131	9.866e-15	75.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158390_k127_2173632_9	1380347.JNII01000007_gene152	1.85e-26	117.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4ET6T@85013|Frankiales	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158390_k127_2173632_7	471852.Tcur_3017	4.779e-32	131.0	COG1426@1|root,COG1426@2|Bacteria,2I2W5@201174|Actinobacteria,4EFNN@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158390_k127_2173632_0	1229780.BN381_100129	1.095e-166	541.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,3UWDX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ACT domain	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158390_k127_2173632_1	644283.Micau_5015	2.303e-151	484.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4DB2H@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
SRR25158390_k127_2173632_8	1193181.BN10_540012	1.136e-26	122.0	COG1694@1|root,COG1694@2|Bacteria,2ISAF@201174|Actinobacteria,4FJCG@85021|Intrasporangiaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158390_k127_2173632_13	479435.Kfla_6080	7.198e-10	70.0	COG3568@1|root,COG3568@2|Bacteria,2HF70@201174|Actinobacteria,4DTXH@85009|Propionibacteriales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_2173632_5	390989.JOEG01000019_gene5970	3.617e-35	140.0	2ECMH@1|root,336JI@2|Bacteria,2IQU7@201174|Actinobacteria,4DF0Q@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2173632_2	390989.JOEG01000019_gene5969	1.023e-95	325.0	28PI0@1|root,2ZC87@2|Bacteria,2IDWK@201174|Actinobacteria,4DACP@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
SRR25158390_k127_2173632_6	1095767.CAHD01000077_gene2757	3.937e-35	156.0	COG2208@1|root,COG4251@1|root,COG2208@2|Bacteria,COG4251@2|Bacteria,2GK8P@201174|Actinobacteria,4F0WE@85016|Cellulomonadaceae	201174|Actinobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,PAS_2,PHY,SpoIIE
SRR25158390_k127_2173632_3	298655.KI912266_gene3054	1.358e-51	192.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158390_k127_2173632_4	1464048.JNZS01000004_gene1436	2.348e-42	170.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria,4DEVM@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158390_k127_2173632_12	1429046.RR21198_0135	8.099e-13	79.0	COG1840@1|root,COG1840@2|Bacteria,2HJ1S@201174|Actinobacteria,4G55M@85025|Nocardiaceae	201174|Actinobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2173632_10	266117.Rxyl_0774	6.789e-18	87.0	2C3PP@1|root,2Z954@2|Bacteria,2IB93@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2184562_2	1229780.BN381_20064	1.075e-74	260.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,3UX0T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118	ko02010,map02010	M00196,M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.3	-	-	BPD_transp_1
SRR25158390_k127_2184562_1	1229780.BN381_20065	1.166e-88	301.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,3UWR1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG0395 ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
SRR25158390_k127_2184562_0	1229780.BN381_20066	3.202e-92	321.0	COG1653@1|root,COG1653@2|Bacteria,2HP0P@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
SRR25158390_k127_2184562_3	479433.Caci_8928	3.667e-37	151.0	2BWWP@1|root,33MND@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2200975_7	1449069.JMLO01000006_gene1186	2.577e-91	316.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4FU1D@85025|Nocardiaceae	201174|Actinobacteria	M	ABC transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158390_k127_2200975_4	1449069.JMLO01000006_gene1187	1.535e-140	459.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FUJH@85025|Nocardiaceae	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2200975_5	298655.KI912266_gene1029	3.05e-112	378.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2200975_16	981369.JQMJ01000004_gene1653	2.254e-15	84.0	COG1246@1|root,COG1246@2|Bacteria,2GJQ8@201174|Actinobacteria,2NHVD@228398|Streptacidiphilus	201174|Actinobacteria	E	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_2200975_13	1449976.KALB_7140	2.062e-33	136.0	COG1309@1|root,COG1309@2|Bacteria,2HR0A@201174|Actinobacteria,4E3IU@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158390_k127_2200975_6	65497.JODV01000014_gene3315	8.052e-104	348.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4DXBF@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_2200975_12	263358.VAB18032_11715	4.317e-40	158.0	2AWFS@1|root,31NC1@2|Bacteria,2IMS0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2200975_0	1123322.KB904659_gene1029	0.0	1393.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria	201174|Actinobacteria	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
SRR25158390_k127_2200975_14	1229780.BN381_130242	2.678e-30	122.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,3UWY5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRR25158390_k127_2200975_1	1229780.BN381_300001	3.203e-194	615.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158390_k127_2200975_10	1370125.AUWT01000033_gene1254	3.062e-66	232.0	COG0607@1|root,COG0607@2|Bacteria,2IB6H@201174|Actinobacteria,2335A@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
SRR25158390_k127_2200975_2	263358.VAB18032_13485	3.107e-160	530.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4D9U7@85008|Micromonosporales	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158390_k127_2200975_3	1209984.BN978_06070	4.77e-144	470.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158390_k127_2200975_11	298655.KI912266_gene3382	4.067e-62	228.0	COG1296@1|root,COG1296@2|Bacteria,2IKHA@201174|Actinobacteria	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158390_k127_2200975_9	2074.JNYD01000023_gene1340	4.996e-73	255.0	COG2120@1|root,COG2120@2|Bacteria,2IDT2@201174|Actinobacteria,4EBAF@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158390_k127_2200975_8	1120949.KB903339_gene8068	2.642e-90	318.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_2202237_8	1240349.ANGC01000061_gene4300	8.724e-23	104.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FUMT@85025|Nocardiaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_2202237_6	1229780.BN381_50135	1.849e-50	189.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158390_k127_2202237_2	1313172.YM304_20360	3.179e-113	387.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CMXJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	3-dehydroquinate synthase	aroB	-	-	ko:K16020	ko01051,ko01130,map01051,map01130	-	R06592	RC00847	ko00000,ko00001	-	-	-	DHQ_synthase
SRR25158390_k127_2202237_1	1313172.YM304_20340	4.074e-179	571.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CMPX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158390_k127_2202237_9	1120949.KB903313_gene419	2.871e-21	104.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4DC76@85008|Micromonosporales	201174|Actinobacteria	NOU	Bacterial Peptidase A24 N-terminal domain	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158390_k127_2202237_10	351607.Acel_1324	7.281e-07	62.0	COG0457@1|root,COG0457@2|Bacteria	351607.Acel_1324|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2202237_5	1313172.YM304_20320	8.437e-62	234.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CN43@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158390_k127_2202237_4	1146883.BLASA_2344	1.221e-65	251.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4ESC2@85013|Frankiales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158390_k127_2202237_7	675635.Psed_3542	7.175e-26	123.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4E3CY@85010|Pseudonocardiales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158390_k127_2202237_0	1229780.BN381_50129	5e-324	1015.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,3UW8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158390_k127_2202237_11	1463855.JOHV01000049_gene3537	4.545e-05	51.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR25158390_k127_2202237_3	1313172.YM304_26410	9.819e-91	307.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158390_k127_2213483_3	298654.FraEuI1c_3065	1.642e-138	449.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158390_k127_2213483_5	279238.Saro_1002	5.356e-84	290.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,2U82N@28211|Alphaproteobacteria,2K5NA@204457|Sphingomonadales	204457|Sphingomonadales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158390_k127_2213483_8	395961.Cyan7425_1329	1.279e-42	168.0	COG1309@1|root,COG1309@2|Bacteria,1G5IR@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2213483_12	675635.Psed_6406	2.524e-15	83.0	COG4843@1|root,COG4843@2|Bacteria,2HBDB@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2213483_2	1089544.KB912942_gene1882	1.224e-159	524.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4DZTG@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158390_k127_2213483_13	1380347.JNII01000009_gene2287	2.727e-06	60.0	COG0477@1|root,COG2814@2|Bacteria,2HBIW@201174|Actinobacteria	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2213483_9	1313172.YM304_25720	1.676e-39	153.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158390_k127_2213483_6	561175.KB894093_gene2781	1.3e-70	260.0	COG0596@1|root,COG0596@2|Bacteria,2GKX3@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2213483_1	471852.Tcur_2027	1.64e-199	634.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4EN7P@85012|Streptosporangiales	201174|Actinobacteria	S	tRNA-splicing ligase RtcB	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158390_k127_2213483_10	469371.Tbis_0834	1.72e-20	99.0	COG1371@1|root,COG1371@2|Bacteria,2IS0V@201174|Actinobacteria,4E6HK@85010|Pseudonocardiales	201174|Actinobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158390_k127_2213483_14	1380356.JNIK01000014_gene3231	0.0003229	52.0	COG0662@1|root,COG0662@2|Bacteria,2II1B@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_2213483_4	1123322.KB904699_gene4621	2.637e-130	427.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_2213483_11	1463825.JNXC01000011_gene258	1.961e-16	89.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria,4E6WI@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
SRR25158390_k127_2213483_7	1229780.BN381_310079	8.953e-60	226.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,3UXS8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158390_k127_2213483_0	1229780.BN381_310078	9.718e-207	647.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158390_k127_225328_17	298654.FraEuI1c_2882	1.288e-36	139.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU00@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_225328_12	1123320.KB889685_gene2189	4.532e-60	221.0	28K5H@1|root,2Z9U4@2|Bacteria,2GKEQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_225328_8	326424.FRAAL1196	5.522e-69	245.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,4ESH2@85013|Frankiales	201174|Actinobacteria	L	TIGRFAM DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158390_k127_225328_18	1370121.AUWS01000071_gene94	4.07e-19	102.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,235MS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	esterase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SRR25158390_k127_225328_4	33898.JRHJ01000087_gene2331	2.395e-106	361.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_225328_3	66869.JNXG01000004_gene2635	1.421e-126	427.0	COG3540@1|root,COG3540@2|Bacteria,2GJCI@201174|Actinobacteria,419TW@629295|Streptomyces griseus group	201174|Actinobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01077,ko:K01113	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	PhoD,PhoD_N
SRR25158390_k127_225328_11	298655.KI912266_gene5601	2.412e-62	242.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_225328_7	1121937.AUHJ01000005_gene2226	1.313e-74	260.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,1SWMP@1236|Gammaproteobacteria,46975@72275|Alteromonadaceae	1224|Proteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_225328_10	246196.MSMEI_2189	2.408e-65	229.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria,2355H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158390_k127_225328_9	1068978.AMETH_5029	9.045e-69	248.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria,4E3U9@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_225328_6	479432.Sros_1987	9.208e-91	307.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EH15@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_225328_15	1313172.YM304_20690	2.531e-50	196.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158390_k127_225328_13	1038862.KB893851_gene6527	7.722e-59	214.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria,2U0F4@28211|Alphaproteobacteria,3JVIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_225328_1	298654.FraEuI1c_3990	7.622e-189	601.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_225328_0	298653.Franean1_6569	2.075e-189	641.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUDE@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158390_k127_225328_16	479431.Namu_5089	2.1e-46	178.0	COG0454@1|root,COG0456@2|Bacteria,2HP83@201174|Actinobacteria,4EW4F@85013|Frankiales	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_225328_2	1123024.AUII01000031_gene527	3.558e-137	449.0	COG0500@1|root,COG2226@2|Bacteria,2I3SA@201174|Actinobacteria,4EF8K@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_225328_5	68194.JNXR01000016_gene7423	3.331e-99	341.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2IAWC@201174|Actinobacteria	201174|Actinobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18
SRR25158390_k127_225328_14	1449353.JQMQ01000005_gene5517	2.462e-50	179.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,2NE96@228398|Streptacidiphilus	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_2266807_0	58123.JOFJ01000019_gene3895	2.708e-220	691.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4EHQW@85012|Streptosporangiales	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158390_k127_2266807_1	118168.MC7420_7920	2.444e-128	436.0	COG0642@1|root,COG2205@2|Bacteria,1G17B@1117|Cyanobacteria,1H8KR@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_2266807_4	1122939.ATUD01000011_gene2274	3.097e-84	308.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2266807_7	1122138.AQUZ01000057_gene6710	1.586e-68	250.0	COG3173@1|root,COG3173@2|Bacteria,2I4D0@201174|Actinobacteria,4DX20@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_2266807_9	1229780.BN381_100221	1.009e-39	154.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158390_k127_2266807_8	1313172.YM304_31180	1.669e-58	216.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K11603	ko02010,ko02020,map02010,map02020	M00316	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.1	-	-	ABC_tran
SRR25158390_k127_2266807_6	570268.ANBB01000100_gene5750	3.755e-75	263.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	mntC	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158390_k127_2266807_5	1313172.YM304_21850	8.328e-81	281.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Mn2 Zn2 transport systems permease components	mntB	-	-	ko:K02075,ko:K09819	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158390_k127_2266807_3	479432.Sros_9057	4.236e-94	335.0	COG1408@1|root,COG1408@2|Bacteria,2GM8M@201174|Actinobacteria,4ER1A@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158390_k127_2266807_2	448385.sce7626	8.003e-120	406.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42RBW@68525|delta/epsilon subdivisions,2X5G8@28221|Deltaproteobacteria,2Z35G@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2266807_10	574966.KB898653_gene1385	3.16e-26	117.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,1S4FU@1236|Gammaproteobacteria,1XRP3@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_2270113_3	1122622.ATWJ01000010_gene1193	3.969e-42	161.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4FF6T@85021|Intrasporangiaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158390_k127_2270113_6	1313172.YM304_41480	1.722e-09	68.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158390_k127_2270113_2	479434.Sthe_1081	1.099e-73	270.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2270113_4	2002.JOEQ01000010_gene6364	5.716e-26	121.0	COG1277@1|root,COG1277@2|Bacteria,2GKKP@201174|Actinobacteria,4EFWG@85012|Streptosporangiales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158390_k127_2270113_1	711393.AYRX01000013_gene3393	4.535e-78	274.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria	201174|Actinobacteria	V	abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2270113_0	1229780.BN381_350131	8.258e-112	376.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
SRR25158390_k127_2270148_9	1121104.AQXH01000001_gene2068	5.488e-58	221.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
SRR25158390_k127_2270148_2	1313172.YM304_02490	2.488e-94	336.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158390_k127_2270148_1	1246474.ANBE01000003_gene2217	1.388e-112	377.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4EGA7@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2270148_7	365528.KB891103_gene4048	5.643e-62	229.0	COG1266@1|root,COG1266@2|Bacteria,2GK11@201174|Actinobacteria,4ESXA@85013|Frankiales	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158390_k127_2270148_5	298654.FraEuI1c_3027	2.887e-78	279.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4ESGN@85013|Frankiales	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158390_k127_2270148_8	287986.DV20_09410	8.87e-59	222.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria,4E2XT@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158390_k127_2270148_3	1172180.KB911786_gene172	4.16e-91	325.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158390_k127_2270148_0	298655.KI912266_gene1000	5.314e-157	511.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4EUA5@85013|Frankiales	201174|Actinobacteria	EGP	drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2270148_6	1206735.BAGG01000260_gene6436	1.832e-73	256.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria,4FUG4@85025|Nocardiaceae	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_2270148_4	931627.MycrhDRAFT_2174	2.844e-78	277.0	COG2761@1|root,COG2761@2|Bacteria,2H7YD@201174|Actinobacteria,2359N@1762|Mycobacteriaceae	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158390_k127_2270148_11	211114.JOEF01000005_gene2357	3.677e-12	75.0	COG1011@1|root,COG1011@2|Bacteria,2GNSS@201174|Actinobacteria,4E1I2@85010|Pseudonocardiales	201174|Actinobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158390_k127_2277502_7	298655.KI912266_gene4687	9.392e-103	343.0	COG0410@1|root,COG0477@1|root,COG0410@2|Bacteria,COG2814@2|Bacteria,2IFX5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,MFS_1
SRR25158390_k127_2277502_0	298653.Franean1_3190	9.615e-249	797.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_2277502_9	247634.GPB2148_2610	7.33e-85	290.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,1S013@1236|Gammaproteobacteria,1J5C8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2277502_2	58344.JOEL01000001_gene350	9.976e-198	636.0	COG2368@1|root,COG2368@2|Bacteria,2GKIQ@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
SRR25158390_k127_2277502_3	472759.Nhal_1703	4.351e-131	426.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158390_k127_2277502_10	101510.RHA1_ro04095	8.441e-77	260.0	COG3832@1|root,COG3832@2|Bacteria,2IHQ1@201174|Actinobacteria,4G1C6@85025|Nocardiaceae	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_2277502_20	547163.BN979_04140	2.615e-34	139.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,23EWU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_2277502_19	1122247.C731_0984	1.113e-38	151.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_2277502_13	1120949.KB903339_gene7839	1.298e-71	251.0	COG0454@1|root,COG0456@2|Bacteria,2GNNG@201174|Actinobacteria,4DD86@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	yjgM	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
SRR25158390_k127_2277502_11	246196.MSMEI_2345	1.84e-72	250.0	COG1309@1|root,COG1309@2|Bacteria,2I9F9@201174|Actinobacteria,238ZH@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2277502_23	222534.KB893717_gene2176	7.982e-19	96.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
SRR25158390_k127_2277502_1	1380390.JIAT01000014_gene6208	1.041e-217	700.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,NB-ARC,Response_reg,TIR_2,TPR_10,TPR_12
SRR25158390_k127_2277502_17	1123024.AUII01000011_gene4438	5.407e-49	185.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158390_k127_2277502_15	1434929.X946_2352	1.075e-57	214.0	COG5486@1|root,COG5486@2|Bacteria,1R6FN@1224|Proteobacteria,2VMCU@28216|Betaproteobacteria,1K22S@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158390_k127_2277502_8	469383.Cwoe_0229	1.427e-90	308.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4CRR7@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158390_k127_2277502_21	2074.JNYD01000011_gene70	4.109e-26	112.0	COG2329@1|root,COG2329@2|Bacteria,2IQBH@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158390_k127_2277502_6	1280949.HAD_00915	7.566e-106	359.0	COG2159@1|root,COG2159@2|Bacteria,1MVTS@1224|Proteobacteria,2VGQX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_2277502_18	1214101.BN159_0570	1.115e-48	178.0	2BVXR@1|root,32IG2@2|Bacteria,2IMT1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158390_k127_2277502_22	477641.MODMU_5094	1.453e-19	102.0	2EMIT@1|root,33F7D@2|Bacteria,2GRD4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2277502_24	1122609.AUGT01000009_gene2946	1.745e-09	70.0	2DMRR@1|root,32T8I@2|Bacteria,2IKQU@201174|Actinobacteria,4DUQ1@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2277502_16	91464.S7335_568	1.913e-55	205.0	COG1266@1|root,COG1266@2|Bacteria,1G9T4@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158390_k127_2277502_5	1211815.CBYP010000069_gene1395	1.898e-109	359.0	COG1028@1|root,COG1028@2|Bacteria,2I95F@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K14633	ko01057,ko01130,map01057,map01130	-	R09309,R09310	RC02484	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158390_k127_2277502_14	298654.FraEuI1c_1589	9.484e-58	206.0	COG0500@1|root,COG0500@2|Bacteria,2I3S9@201174|Actinobacteria	201174|Actinobacteria	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_2277502_12	1123320.KB889574_gene5517	3.247e-72	257.0	COG1028@1|root,COG1028@2|Bacteria,2GM6W@201174|Actinobacteria	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities related to short-chain alcohol dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158390_k127_2277502_4	1394178.AWOO02000004_gene2428	9.278e-111	391.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
SRR25158390_k127_2298127_6	479435.Kfla_0703	3.432e-52	192.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4DV29@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2298127_4	1123322.KB904635_gene2634	7.47e-102	338.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_2298127_1	1123322.KB904635_gene2633	2.824e-124	405.0	COG2378@1|root,COG2378@2|Bacteria,2GKTS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_2298127_11	710111.FraQA3DRAFT_2104	0.0006332	52.0	2DGCV@1|root,2ZVG4@2|Bacteria,2IARW@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3068)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3068
SRR25158390_k127_2298127_0	1242864.D187_001549	5.986e-188	624.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_2298127_9	1068978.AMETH_4967	8.327e-21	102.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_2298127_7	1206731.BAGB01000035_gene9155	1.762e-45	171.0	COG2259@1|root,COG2259@2|Bacteria,2IMX8@201174|Actinobacteria,4G1GN@85025|Nocardiaceae	201174|Actinobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158390_k127_2298127_10	1045009.AFXQ01000011_gene450	2.121e-11	72.0	COG1309@1|root,COG1309@2|Bacteria,2IBVF@201174|Actinobacteria,1WC5P@1268|Micrococcaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2298127_5	1120936.KB907208_gene1207	9.77e-87	307.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2298127_2	1048339.KB913029_gene3698	9.453e-119	387.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4EURW@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2298127_3	47839.CCAU010000011_gene5318	1.715e-116	391.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria,23ACA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158390_k127_2298127_8	446468.Ndas_1353	6.718e-41	154.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,2GJB4@201174|Actinobacteria,4EG8R@85012|Streptosporangiales	201174|Actinobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158390_k127_2317714_1	1229780.BN381_50059	7.523e-77	286.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,3UWX5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158390_k127_2317714_0	1120936.KB907209_gene1722	9.889e-113	383.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4EG5Z@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,DBI_PRT,Nitroreductase
SRR25158390_k127_2317714_2	1380394.JADL01000002_gene1561	3.114e-19	98.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2U97D@28211|Alphaproteobacteria,2JSSP@204441|Rhodospirillales	204441|Rhodospirillales	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158390_k127_2317714_3	935866.JAER01000077_gene1471	1.271e-10	64.0	COG3547@1|root,COG3547@2|Bacteria,2IDDB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3512a	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_2327687_9	561175.KB894093_gene3888	4.984e-76	291.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158390_k127_2327687_5	1313172.YM304_33030	3.019e-81	282.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CN2X@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158390_k127_2327687_7	1313172.YM304_33050	2.233e-79	274.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CN5A@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158390_k127_2327687_8	1229780.BN381_20098	2.835e-78	271.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,3UWNZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158390_k127_2327687_1	1128421.JAGA01000001_gene2297	1.062e-99	331.0	COG0262@1|root,COG0262@2|Bacteria,2NRYY@2323|unclassified Bacteria	2|Bacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_2327687_0	1068980.ARVW01000001_gene6641	3.024e-188	595.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4DXSS@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR25158390_k127_2327687_4	1121877.JQKF01000040_gene1861	6.337e-84	287.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158390_k127_2327687_6	1037409.BJ6T_09520	3.473e-81	288.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,3JWFY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	MA20_23235	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
SRR25158390_k127_2327687_10	1229780.BN381_130206	1.669e-58	222.0	COG0500@1|root,COG0500@2|Bacteria,2I78T@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158390_k127_2327687_3	1068978.AMETH_6735	1.49e-89	313.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4E29J@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_2327687_11	351607.Acel_1424	1.088e-12	70.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,4EWY4@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2327687_12	1242864.D187_007437	7.975e-05	52.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,42WRW@68525|delta/epsilon subdivisions,2WRCW@28221|Deltaproteobacteria,2YV18@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2327687_2	472759.Nhal_2701	5.943e-90	302.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158390_k127_2332624_2	1150599.MPHLEI_12391	1.202e-10	65.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,233ZQ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_2332624_0	710687.KI912270_gene1294	6.806e-151	514.0	COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRR25158390_k127_2332624_1	1299327.I546_0209	1.618e-15	82.0	COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,23D5I@1762|Mycobacteriaceae	201174|Actinobacteria	K	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRR25158390_k127_2347747_5	1313172.YM304_26740	2.747e-31	128.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CN96@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158390_k127_2347747_3	1313172.YM304_26760	2.805e-68	241.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CN49@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158390_k127_2347747_1	869210.Marky_0319	1.358e-124	421.0	COG1488@1|root,COG1488@2|Bacteria,1WIWH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158390_k127_2347747_2	1313172.YM304_26770	5.603e-110	364.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CMST@84992|Acidimicrobiia	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Helicase_C,ResIII,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_2347747_0	1313172.YM304_26780	1.207e-215	676.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158390_k127_2347747_4	1229780.BN381_50029	1.271e-44	175.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,3UXN4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR25158390_k127_2373346_3	1128421.JAGA01000002_gene1417	3.615e-47	179.0	COG2178@1|root,COG2178@2|Bacteria,2NR1U@2323|unclassified Bacteria	2|Bacteria	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_2373346_0	443218.AS9A_3072	2.853e-87	306.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,23BIX@1762|Mycobacteriaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_2373346_4	2074.JNYD01000015_gene4381	9.269e-37	150.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2373346_2	2002.JOEQ01000008_gene1052	5.516e-68	243.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4EIE1@85012|Streptosporangiales	201174|Actinobacteria	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_2373346_1	134676.ACPL_4096	4.393e-79	278.0	COG3612@1|root,COG3612@2|Bacteria,2GN7K@201174|Actinobacteria,4DEZF@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2373346_5	710686.Mycsm_03429	3.239e-16	85.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158390_k127_2391763_1	1089551.KE386572_gene909	1.19e-106	368.0	COG1404@1|root,COG1404@2|Bacteria,1PG3I@1224|Proteobacteria,2V8W1@28211|Alphaproteobacteria,4BSXU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158390_k127_2391763_2	1123024.AUII01000010_gene679	6e-93	314.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4E0T5@85010|Pseudonocardiales	201174|Actinobacteria	KP	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
SRR25158390_k127_2391763_0	1157943.KB892706_gene4166	3.016e-156	499.0	COG0477@1|root,COG2814@2|Bacteria,2GNBV@201174|Actinobacteria,2387P@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2453024_8	1206744.BAGL01000054_gene1682	4.317e-46	182.0	COG2378@1|root,COG2378@2|Bacteria,2H5IT@201174|Actinobacteria,4G13P@85025|Nocardiaceae	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_2453024_11	1049564.TevJSym_aa00380	5.674e-26	113.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria,1J66R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_2453024_2	882086.SacxiDRAFT_3491	2.522e-120	394.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DXEI@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_2453024_0	1123320.KB889696_gene9123	8.751e-166	539.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_2453024_4	471852.Tcur_2585	8.085e-90	313.0	COG3173@1|root,COG3173@2|Bacteria,2I8YI@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
SRR25158390_k127_2453024_6	469383.Cwoe_1255	6.325e-81	299.0	COG0457@1|root,COG0457@2|Bacteria	469383.Cwoe_1255|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2453024_10	530564.Psta_1246	2.632e-29	136.0	COG3391@1|root,COG3391@2|Bacteria,2J1IA@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2453024_9	243230.DR_1148	2.012e-41	157.0	COG0490@1|root,COG0490@2|Bacteria,1WJS3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	regulatory, ligand-binding protein related to C-terminal domains of K channels	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158390_k127_2453024_1	1123320.KB889704_gene9382	1.607e-129	427.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158390_k127_2453024_7	1229780.BN381_30015	1.578e-50	207.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,3UXHV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS_4,SpoIIE
SRR25158390_k127_2453024_12	1463841.JOIR01000056_gene29	4.207e-12	72.0	COG1366@1|root,COG1366@2|Bacteria,2GUNY@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
SRR25158390_k127_2453024_3	1229780.BN381_300002	4.473e-94	316.0	COG2188@1|root,COG2188@2|Bacteria,2HFQN@201174|Actinobacteria,3UXMM@52018|unclassified Actinobacteria (class)	2|Bacteria	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158390_k127_2453024_5	1996.JOFO01000023_gene4000	1.197e-87	305.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,4EIB6@85012|Streptosporangiales	201174|Actinobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158390_k127_2455014_5	1229780.BN381_110030	6.863e-55	197.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,3UWKZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158390_k127_2455014_6	469383.Cwoe_2890	4.114e-45	167.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4CSPV@84995|Rubrobacteria	84995|Rubrobacteria	H	Aspartate decarboxylase	-	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158390_k127_2455014_0	1229780.BN381_110031	1.401e-182	593.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,3UW8F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Fumarate reductase flavoprotein C-term	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
SRR25158390_k127_2455014_2	1313172.YM304_37700	4.267e-99	332.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
SRR25158390_k127_2455014_3	1229780.BN381_110032	3.872e-95	320.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,3UWIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158390_k127_2455014_4	1229780.BN381_110048	2.458e-87	320.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,3UWI1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158390_k127_2455014_1	1229780.BN381_110049	4.397e-125	417.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158390_k127_2458445_3	1027371.GOALK_070_00010	1.259e-66	242.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,4GFSJ@85026|Gordoniaceae	201174|Actinobacteria	L	PFAM integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_2458445_1	710696.Intca_0313	6.461e-129	421.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,4FIN9@85021|Intrasporangiaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_2458445_7	196162.Noca_1618	3.887e-25	110.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
SRR25158390_k127_2458445_4	710421.Mycch_2074	2.645e-61	216.0	arCOG11509@1|root,31KIR@2|Bacteria,2IGM0@201174|Actinobacteria,23A9A@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2458445_8	1463934.JOCF01000018_gene3969	3.851e-11	73.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158390_k127_2458445_2	1435356.Y013_17945	3.405e-109	362.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4FYA9@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_2458445_5	518766.Rmar_1536	1.673e-53	197.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1FJEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
SRR25158390_k127_2458445_6	479434.Sthe_3439	7.217e-37	149.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	200795|Chloroflexi	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_2458445_0	1429046.RR21198_3070	1.831e-141	466.0	COG1012@1|root,COG1012@2|Bacteria,2GMNB@201174|Actinobacteria,4FW58@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_2470066_3	1229780.BN381_330092	2.967e-11	66.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,3UWJR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158390_k127_2470066_0	66875.JODY01000036_gene3003	2.18e-178	575.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_2470066_1	1449346.JQMO01000003_gene3726	2.206e-113	379.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,2M0N9@2063|Kitasatospora	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158390_k127_2470066_2	1229780.BN381_330079	1.686e-82	281.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,3UW68@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158390_k127_2479834_5	1313172.YM304_21410	4.417e-53	190.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CMW4@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158390_k127_2479834_2	1229780.BN381_100036	7.161e-82	283.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25,Methyltransf_31
SRR25158390_k127_2479834_0	1229780.BN381_80407	0.0	1103.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,3UWEE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158390_k127_2479834_3	1313172.YM304_21370	1.5e-73	252.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CN3I@84992|Acidimicrobiia	84992|Acidimicrobiia	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158390_k127_2479834_6	1313172.YM304_21360	7.687e-16	87.0	29B43@1|root,2ZY2Q@2|Bacteria,2HD3P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2479834_4	105422.BBPM01000034_gene1241	1.116e-53	204.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,2NGYF@228398|Streptacidiphilus	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_2479834_1	1122611.KB903940_gene1759	2.063e-189	609.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4EGEU@85012|Streptosporangiales	201174|Actinobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158390_k127_2491877_4	1313172.YM304_06940	2.22e-70	242.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CNFE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2491877_2	1230476.C207_00815	1.868e-101	355.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158390_k127_2491877_7	460265.Mnod_4690	1.319e-24	120.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,1JU2Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158390_k127_2491877_5	1298863.AUEP01000011_gene623	7.603e-54	193.0	COG2030@1|root,COG2030@2|Bacteria,2IK2Z@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_2491877_8	1463820.JOGW01000005_gene3511	1.047e-19	98.0	COG1309@1|root,COG1309@2|Bacteria,2IEU9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2491877_1	1229780.BN381_10242	3.782e-141	484.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_2491877_0	1229780.BN381_10243	1.827e-312	992.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_2491877_3	1229780.BN381_10244	1.084e-84	303.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2491877_6	1229780.BN381_10244	2.494e-43	174.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_25097_2	1298863.AUEP01000008_gene1241	8.768e-84	294.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_25097_0	1298863.AUEP01000008_gene1242	3.675e-174	564.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DTCF@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_25097_1	1123023.JIAI01000002_gene5557	7.813e-97	323.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_25097_4	1313172.YM304_41520	2.887e-80	276.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158390_k127_25097_3	1435356.Y013_10300	5.139e-81	277.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4FWF5@85025|Nocardiaceae	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158390_k127_2528297_5	1240349.ANGC01000037_gene3150	3.367e-07	62.0	COG1960@1|root,COG1960@2|Bacteria,2HHFP@201174|Actinobacteria,4FYH6@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
SRR25158390_k127_2528297_1	1240349.ANGC01000037_gene3151	5.389e-103	347.0	COG2120@1|root,COG2120@2|Bacteria,2IDT2@201174|Actinobacteria,4G0KD@85025|Nocardiaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158390_k127_2528297_3	1415754.JQMK01000012_gene909	9.647e-57	203.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,464MC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158390_k127_2528297_0	1122933.JNIY01000003_gene699	8.608e-272	853.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,2GJ5U@201174|Actinobacteria,4F0GJ@85016|Cellulomonadaceae	201174|Actinobacteria	C	belongs to the CobB CobQ family	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
SRR25158390_k127_2528297_4	1449976.KALB_1266	1.426e-34	153.0	COG3427@1|root,COG3427@2|Bacteria,2I5DX@201174|Actinobacteria,4EDWB@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_2528297_2	1123024.AUII01000024_gene249	2.975e-66	229.0	COG0678@1|root,COG0678@2|Bacteria,2IP2N@201174|Actinobacteria	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR25158390_k127_2528297_6	211114.JOEF01000015_gene3539	0.0009663	51.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E4X4@85010|Pseudonocardiales	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158390_k127_2532649_2	1229780.BN381_80028	1.295e-116	389.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,3UWAR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158390_k127_2532649_4	35754.JNYJ01000022_gene8077	1.637e-27	122.0	COG1595@1|root,COG1595@2|Bacteria,2GWFT@201174|Actinobacteria,4DJEK@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2532649_1	405948.SACE_7066	7.264e-214	686.0	COG3525@1|root,COG3525@2|Bacteria,2GM4H@201174|Actinobacteria,4DZWB@85010|Pseudonocardiales	201174|Actinobacteria	G	beta-N-acetylglucosaminidase	-	-	3.2.1.35	ko:K01197	ko00531,ko01100,map00531,map01100	M00076,M00077	R07824,R07825,R10905	-	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	-	-	F5_F8_type_C,Glyco_hydro_20b,NAGidase
SRR25158390_k127_2532649_3	1313172.YM304_29090	7.93e-37	149.0	2BJWW@1|root,32E9A@2|Bacteria,2HGG7@201174|Actinobacteria,4CNDN@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2532649_0	525368.HMPREF0591_5879	9.898e-297	927.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,236N9@1762|Mycobacteriaceae	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158390_k127_2532649_5	1211815.CBYP010000069_gene1348	1.272e-16	81.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158390_k127_2539257_1	365528.KB891241_gene6196	1.541e-120	398.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4ERMI@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158390_k127_2539257_0	1120950.KB892761_gene5807	0.0	1219.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4DNF9@85009|Propionibacteriales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158390_k127_2539257_3	391037.Sare_3380	8.762e-52	208.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria,4D9HZ@85008|Micromonosporales	201174|Actinobacteria	S	membrane transporter protein	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_2539257_2	28444.JODQ01000002_gene3962	5.098e-62	230.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EMDD@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158390_k127_2542024_2	66373.JOFQ01000001_gene1557	8.478e-51	185.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_2542024_4	882083.SacmaDRAFT_3624	2.368e-11	72.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria,4E7TB@85010|Pseudonocardiales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158390_k127_2542024_3	1869.MB27_35150	2.078e-13	83.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4DD13@85008|Micromonosporales	201174|Actinobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_2542024_0	656024.FsymDg_2709	3.418e-64	231.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4ESAK@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158390_k127_2542024_1	656024.FsymDg_2708	2.814e-54	201.0	COG0457@1|root,COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4585@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4585@2|Bacteria,2HFBH@201174|Actinobacteria,4EUB9@85013|Frankiales	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,HATPase_c,Pkinase
SRR25158390_k127_2542904_1	365528.KB891115_gene1604	9.013e-93	332.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EUMV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158390_k127_2542904_6	1133850.SHJG_0405	3.022e-53	202.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2542904_7	1121946.AUAX01000004_gene909	4.535e-18	99.0	COG5401@1|root,COG5401@2|Bacteria,2IRGJ@201174|Actinobacteria,4DF2T@85008|Micromonosporales	201174|Actinobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SRR25158390_k127_2542904_2	263358.VAB18032_22435	1.649e-90	315.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,2GK1J@201174|Actinobacteria,4D9Q6@85008|Micromonosporales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_2542904_0	298655.KI912266_gene5582	1.193e-133	438.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_2542904_4	222534.KB893716_gene1819	1.765e-81	282.0	COG0778@1|root,COG0778@2|Bacteria,2I94X@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_2542904_5	1155718.KB891879_gene4965	7.06e-79	270.0	COG0693@1|root,COG0693@2|Bacteria,2H6FV@201174|Actinobacteria	201174|Actinobacteria	S	ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158390_k127_2542904_3	1229780.BN381_150092	7.836e-84	288.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,3UXD7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158390_k127_255088_17	1077972.ARGLB_037_01510	1.912e-05	52.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,1WB5M@1268|Micrococcaceae	201174|Actinobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158390_k127_255088_7	1121877.JQKF01000001_gene1317	1.102e-93	317.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CMZ6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158390_k127_255088_6	1313172.YM304_14820	4.07e-160	520.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CMVJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158390_k127_255088_11	1229780.BN381_210086	4.847e-65	227.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,3UWVS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NifU-like N terminal domain	sufU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158390_k127_255088_15	1128427.KB904821_gene4252	5.22e-24	108.0	COG2154@1|root,COG2154@2|Bacteria,1G992@1117|Cyanobacteria,1HHJQ@1150|Oscillatoriales	1117|Cyanobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158390_k127_255088_3	1229780.BN381_250059	1.571e-182	585.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,3UXBP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_255088_1	1121385.AQXW01000004_gene3170	8.039e-217	685.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158390_k127_255088_2	656024.FsymDg_3075	4.412e-193	642.0	COG2114@1|root,COG2909@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
SRR25158390_k127_255088_0	215803.DB30_8791	4.922e-285	917.0	COG2267@1|root,COG2303@1|root,COG2908@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,COG2908@2|Bacteria,1QQ8F@1224|Proteobacteria,42PWF@68525|delta/epsilon subdivisions,2WKVA@28221|Deltaproteobacteria,2YYIQ@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158390_k127_255088_4	1136417.AZWE01000023_gene1211	8.631e-182	615.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4D93G@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158390_k127_255088_8	235985.BBPN01000003_gene4673	5.111e-75	260.0	COG3832@1|root,COG3832@2|Bacteria,2IG6F@201174|Actinobacteria,2NMDQ@228398|Streptacidiphilus	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_255088_12	644283.Micau_0720	7.665e-39	148.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,4DFMJ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_255088_9	745310.G432_08800	7.654e-73	254.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,2K0E3@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158390_k127_255088_16	1463858.JOHR01000016_gene5418	5.396e-24	106.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158390_k127_255088_10	525904.Tter_1697	8.667e-69	250.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
SRR25158390_k127_255088_14	1313172.YM304_30880	3.148e-35	156.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158390_k127_255088_13	1229780.BN381_210073	7.517e-38	146.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_255088_5	525909.Afer_0543	1.651e-181	571.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CMQU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158390_k127_2562432_1	1229780.BN381_100028	3.171e-74	256.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158390_k127_2562432_6	298654.FraEuI1c_6808	2.078e-20	99.0	COG1309@1|root,COG1309@2|Bacteria,2GUIR@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2562432_10	1463934.JOCF01000011_gene4418	0.0003058	49.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158390_k127_2562432_0	1394178.AWOO02000049_gene6151	8.168e-116	387.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EFUR@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_2562432_2	309801.trd_0548	2.428e-65	245.0	COG0842@1|root,COG0842@2|Bacteria,2G6H9@200795|Chloroflexi,27Y1P@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2562432_4	306281.AJLK01000039_gene3427	5.969e-36	156.0	COG0500@1|root,COG2226@2|Bacteria,1G4JN@1117|Cyanobacteria,1JJFD@1189|Stigonemataceae	1117|Cyanobacteria	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158390_k127_2562432_7	4572.TRIUR3_12898-P1	2.096e-10	70.0	COG0589@1|root,2RXWD@2759|Eukaryota,37UWB@33090|Viridiplantae,3GI2N@35493|Streptophyta,3KZ66@4447|Liliopsida,3IH6Z@38820|Poales	35493|Streptophyta	T	Universal stress protein A-like protein	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_2562432_5	1463901.JOIY01000005_gene1756	7.698e-30	131.0	2CDI4@1|root,32YR4@2|Bacteria,2IINI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2562432_8	309801.trd_A0238	1.29e-08	65.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,27YAE@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_2562432_3	317936.Nos7107_3771	1.427e-61	228.0	COG2343@1|root,COG2343@2|Bacteria,1G50P@1117|Cyanobacteria,1HMC7@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158390_k127_2568823_16	1229780.BN381_310071	1.256e-73	254.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,3UWNK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158390_k127_2568823_9	1313172.YM304_09900	1.153e-88	306.0	COG1597@1|root,COG1597@2|Bacteria,2HH1A@201174|Actinobacteria,4CP1H@84992|Acidimicrobiia	2|Bacteria	G	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158390_k127_2568823_28	1313172.YM304_09890	3.473e-41	162.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_2568823_31	1229780.BN381_310068	2.804e-34	147.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,3UWR8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_2568823_6	1313172.YM304_09850	1.535e-126	440.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
SRR25158390_k127_2568823_3	1229780.BN381_310066	6.885e-144	482.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_2568823_8	1229780.BN381_310065	1.482e-111	372.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_2568823_44	525909.Afer_0348	8.204e-17	83.0	2E3M2@1|root,31DE4@2|Bacteria,2HH0X@201174|Actinobacteria,4CP16@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158390_k127_2568823_39	1157640.AQWO01000003_gene5759	5.397e-20	100.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_2568823_52	1206741.BAFX01000095_gene4663	0.0007743	49.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158390_k127_2568823_15	525909.Afer_0762	6.618e-74	256.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158390_k127_2568823_2	1229780.BN381_310061	1.285e-182	577.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,3UWC1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158390_k127_2568823_30	1121877.JQKF01000016_gene162	8.248e-41	162.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_2568823_5	1229780.BN381_310060	4.553e-128	419.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,3UWEF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158390_k127_2568823_43	1313172.YM304_09680	7.517e-19	101.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158390_k127_2568823_36	1313172.YM304_09660	7.491e-26	116.0	COG3088@1|root,COG3088@2|Bacteria,2GTYU@201174|Actinobacteria	201174|Actinobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158390_k127_2568823_29	1229780.BN381_310055	3.493e-41	175.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158390_k127_2568823_1	1229780.BN381_310054	5.51e-251	794.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158390_k127_2568823_33	1229780.BN381_310053	1.847e-31	135.0	COG2332@1|root,COG2332@2|Bacteria,2GZPB@201174|Actinobacteria	201174|Actinobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158390_k127_2568823_23	1229780.BN381_310051	2.433e-57	218.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria	201174|Actinobacteria	O	cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158390_k127_2568823_22	1229780.BN381_310050	2.281e-57	209.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria	201174|Actinobacteria	O	heme exporter protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158390_k127_2568823_17	1229780.BN381_310049	4.285e-70	245.0	COG1131@1|root,COG1131@2|Bacteria,2IRXJ@201174|Actinobacteria	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158390_k127_2568823_25	1229780.BN381_310048	8.962e-55	211.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,3UXMS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 5 No homology to any previously reported sequences	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158390_k127_2568823_34	1449069.JMLO01000017_gene3294	3.122e-31	129.0	COG1714@1|root,COG1714@2|Bacteria,2GS9U@201174|Actinobacteria,4G38W@85025|Nocardiaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_2568823_24	1313172.YM304_09570	7.109e-56	209.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA6	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2568823_50	935866.JAER01000037_gene578	1.204e-09	69.0	COG2013@1|root,COG2013@2|Bacteria,2GSX6@201174|Actinobacteria,4DPJ8@85009|Propionibacteriales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF2510
SRR25158390_k127_2568823_21	1229780.BN381_310040	7.813e-58	207.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,3UWW4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2568823_0	710696.Intca_0881	1.548e-311	988.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria,4FIMN@85021|Intrasporangiaceae	201174|Actinobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
SRR25158390_k127_2568823_45	1122182.KB903818_gene1923	1.63e-16	90.0	2BWWR@1|root,2ZG0F@2|Bacteria,2IJ2X@201174|Actinobacteria,4DDGM@85008|Micromonosporales	201174|Actinobacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2568823_7	1120950.KB892742_gene3055	1.822e-119	394.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4DR7K@85009|Propionibacteriales	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR25158390_k127_2568823_10	1173020.Cha6605_6172	2.927e-86	296.0	COG0500@1|root,COG2226@2|Bacteria,1GAXU@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_2568823_26	477641.MODMU_3260	1.542e-50	191.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4EVH9@85013|Frankiales	201174|Actinobacteria	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_2568823_12	1380393.JHVP01000003_gene810	5.696e-78	269.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4ESXN@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_2568823_27	1996.JOFO01000001_gene3942	2.346e-42	157.0	COG2002@1|root,COG2002@2|Bacteria,2I3FX@201174|Actinobacteria	201174|Actinobacteria	K	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158390_k127_2568823_41	1112204.GPOL_c00110	3.047e-19	92.0	2DSC0@1|root,33FF9@2|Bacteria,2HB1X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2568823_40	105425.BBPL01000013_gene1690	1.167e-19	98.0	COG0640@1|root,COG0640@2|Bacteria,2H1MC@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_2568823_19	1128421.JAGA01000002_gene1080	3.436e-64	238.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
SRR25158390_k127_2568823_13	196490.AUEZ01000037_gene2928	1.684e-75	283.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2TQQR@28211|Alphaproteobacteria,3JTWJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158390_k127_2568823_46	1146883.BLASA_2770	1.907e-16	83.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158390_k127_2568823_37	1206731.BAGB01000157_gene5868	3.994e-22	102.0	COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria,4G9PR@85025|Nocardiaceae	201174|Actinobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TPMT
SRR25158390_k127_2568823_42	1146883.BLASA_1416	3.503e-19	91.0	COG2337@1|root,COG2337@2|Bacteria,2IMGQ@201174|Actinobacteria	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_2568823_14	1123320.KB889664_gene1044	2.93e-74	261.0	COG0500@1|root,COG0500@2|Bacteria,2I2WB@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
SRR25158390_k127_2568823_18	1206729.BAFZ01000164_gene5629	5.651e-69	244.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4G1YB@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2568823_4	1449346.JQMO01000002_gene1161	4.942e-130	426.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,2M0X5@2063|Kitasatospora	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_2568823_11	298655.KI912266_gene2734	3.656e-85	288.0	COG1028@1|root,COG1028@2|Bacteria,2HEWC@201174|Actinobacteria,4EV16@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158390_k127_2568823_49	928724.SacglDRAFT_02487	6.177e-12	78.0	COG1309@1|root,COG1309@2|Bacteria,2IM5N@201174|Actinobacteria,4E50A@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_2568823_32	344747.PM8797T_14354	1.12e-31	140.0	COG0793@1|root,COG2234@1|root,COG0793@2|Bacteria,COG2234@2|Bacteria,2IXR2@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M28
SRR25158390_k127_2568823_35	543632.JOJL01000020_gene528	8.46e-28	117.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4DEWK@85008|Micromonosporales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_2568823_20	1048339.KB913029_gene4145	1.004e-63	229.0	28HG7@1|root,32T0H@2|Bacteria,2IFQ1@201174|Actinobacteria,4EVYV@85013|Frankiales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_2568823_47	1304865.JAGF01000001_gene1006	3.67e-16	78.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158390_k127_2582434_9	1120948.KB903243_gene2730	9.733e-05	46.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,4E4H3@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_2582434_4	2074.JNYD01000002_gene5431	1.079e-27	124.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4DYM3@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_2582434_7	1146883.BLASA_1740	1.18e-08	66.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_2582434_2	106370.Francci3_2500	8.277e-32	130.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria,4ETIV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158390_k127_2582434_1	1449069.JMLO01000035_gene2669	1.724e-191	619.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4FZU3@85025|Nocardiaceae	201174|Actinobacteria	P	Voltage gated chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158390_k127_2582434_3	1229780.BN381_220038	2.724e-30	126.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
SRR25158390_k127_2582434_5	595537.Varpa_0677	5.392e-15	77.0	COG1661@1|root,COG1661@2|Bacteria,1RJC1@1224|Proteobacteria,2VXP3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR25158390_k127_2582434_8	67332.FM21_35610	2.069e-05	51.0	COG1661@1|root,COG1661@2|Bacteria,2ISKT@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR25158390_k127_2582434_0	1089545.KB913037_gene3460	0.0	1290.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4E1FM@85010|Pseudonocardiales	201174|Actinobacteria	L	SNF2 family N-terminal domain	helZ	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
SRR25158390_k127_2582434_6	1128421.JAGA01000001_gene2102	1.896e-11	66.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
SRR25158390_k127_2606919_0	335543.Sfum_1219	3.852e-150	485.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MQW6@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_2606919_6	570268.ANBB01000035_gene2355	1.242e-62	223.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4EHYC@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158390_k127_2606919_5	1313172.YM304_19170	8.785e-74	268.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CNH1@84992|Acidimicrobiia	201174|Actinobacteria	G	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158390_k127_2606919_10	926569.ANT_25860	9.745e-25	117.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi	200795|Chloroflexi	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2,eRF1_3
SRR25158390_k127_2606919_3	397278.JOJN01000004_gene1185	1.318e-114	383.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4DPCJ@85009|Propionibacteriales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158390_k127_2606919_7	1313172.YM304_19160	1.64e-38	151.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4CN9D@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158390_k127_2606919_11	1229780.BN381_140041	1.873e-08	62.0	28Z2K@1|root,2ZKV3@2|Bacteria,2HA4X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2606919_2	1313172.YM304_19140	1.563e-129	423.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4CN28@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2606919_4	1229780.BN381_140043	1.51e-100	344.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SRR25158390_k127_2606919_13	526225.Gobs_3334	6.767e-05	49.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria,4ETGC@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2606919_8	1313172.YM304_19100	1.426e-32	144.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria	201174|Actinobacteria	M	RNA-binding protein containing a PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158390_k127_2606919_9	1229780.BN381_140045	4.09e-25	108.0	2ES7R@1|root,33JSG@2|Bacteria,2I1DU@201174|Actinobacteria,3UXPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2606919_1	1229780.BN381_140046	1.188e-149	498.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,3UWMB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	GIY-YIG type nucleases (URI domain)	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158390_k127_2606919_12	1306174.JODP01000005_gene1654	4.272e-05	55.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_2619421_8	1229780.BN381_90069	1.902e-43	175.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
SRR25158390_k127_2619421_6	1229780.BN381_90069	7.907e-51	198.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
SRR25158390_k127_2619421_4	103733.JNYO01000004_gene7908	1.565e-79	273.0	COG1024@1|root,COG1024@2|Bacteria,2H2G7@201174|Actinobacteria,4DZ8V@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA14	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2619421_5	1313172.YM304_33450	1.915e-76	260.0	COG1670@1|root,COG1670@2|Bacteria,2HFKU@201174|Actinobacteria,4CP4F@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158390_k127_2619421_1	1146883.BLASA_2336	1.614e-159	510.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R10908	RC00006,RC00008,RC00018,RC03305	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158390_k127_2619421_3	1137269.AZWL01000034_gene2492	1.692e-81	289.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158390_k127_2619421_7	1229780.BN381_630015	5.643e-44	166.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,3UWSU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158390_k127_2619421_9	262316.MAP_2672	8.725e-30	135.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158390_k127_2619421_10	65497.JODV01000008_gene47	1.72e-26	124.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4E31D@85010|Pseudonocardiales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_2619421_2	1313172.YM304_36700	2.507e-106	357.0	COG0208@1|root,COG0208@2|Bacteria,2GKGZ@201174|Actinobacteria	201174|Actinobacteria	F	PFAM Fatty acid desaturase, type 2	desA	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
SRR25158390_k127_2619421_0	1313172.YM304_33170	5.389e-199	630.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CMRI@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158390_k127_2625383_0	644283.Micau_3621	7.485e-295	917.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4D9SG@85008|Micromonosporales	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158390_k127_2625383_17	585531.HMPREF0063_12827	1.041e-20	95.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4DSKE@85009|Propionibacteriales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158390_k127_2625383_3	1089546.AQUI01000002_gene3138	3.08e-215	678.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,40A50@622450|Actinopolysporales	201174|Actinobacteria	P	Rhodanese Homology Domain	blh	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158390_k127_2625383_11	2074.JNYD01000001_gene6180	4.452e-129	429.0	COG2267@1|root,COG2267@2|Bacteria,2I2KD@201174|Actinobacteria,4EF63@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	ephA	GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2625383_1	710685.MycrhN_1047	3.703e-234	737.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,232ME@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD13	GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2625383_20	604354.TSIB_1710	1.584e-09	62.0	arCOG03911@1|root,arCOG03911@2157|Archaea,2Y7IE@28890|Euryarchaeota,244G7@183968|Thermococci	183968|Thermococci	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158390_k127_2625383_8	1449069.JMLO01000003_gene4138	1.332e-172	559.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4FUGX@85025|Nocardiaceae	201174|Actinobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158390_k127_2625383_18	323097.Nham_2692	1.25e-18	93.0	COG1141@1|root,COG1141@2|Bacteria,1MZJU@1224|Proteobacteria,2UCKK@28211|Alphaproteobacteria,3K07G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	MA20_16570	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
SRR25158390_k127_2625383_6	1394178.AWOO02000014_gene7681	3.951e-193	616.0	COG2124@1|root,COG2124@2|Bacteria,2HMMY@201174|Actinobacteria,4ENAU@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_2625383_5	497321.C664_07223	5.854e-197	645.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_2625383_12	1304865.JAGF01000001_gene1313	2.001e-127	422.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_2625383_7	1229780.BN381_290013	1.968e-181	580.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	2|Bacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_2625383_15	350054.Mflv_0928	6.557e-54	198.0	COG1848@1|root,COG1848@2|Bacteria,2IJ89@201174|Actinobacteria,239HU@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_2625383_16	419947.MRA_2118	1.001e-24	109.0	2DSMH@1|root,33GPM@2|Bacteria,2GR8G@201174|Actinobacteria,23BKG@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2625383_4	219305.MCAG_04142	1.935e-211	695.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DA3Q@85008|Micromonosporales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_2625383_14	469383.Cwoe_1816	2.84e-89	316.0	COG0438@1|root,COG0438@2|Bacteria,2GR58@201174|Actinobacteria,4CPE6@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2625383_2	525904.Tter_2842	2.595e-221	698.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	1.14.18.2	ko:K08080,ko:K14952	ko00520,ko05152,map00520,map05152	-	R01115,R01803	RC00157	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_3,Rieske
SRR25158390_k127_2625383_13	318424.EU78_13220	2.96e-100	351.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,2360Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_2625383_10	287986.DV20_43270	6.186e-140	456.0	COG0016@1|root,COG0016@2|Bacteria,2GN8Y@201174|Actinobacteria,4DZ8I@85010|Pseudonocardiales	201174|Actinobacteria	J	tRNA synthetases class II core domain (F)	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	FDX-ACB,tRNA-synt_2d
SRR25158390_k127_2625383_9	450851.PHZ_c0252	1.494e-168	548.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2KEZN@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_2626195_5	1313172.YM304_12570	1.873e-34	142.0	2CDEB@1|root,2ZRID@2|Bacteria,2HDK8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2626195_3	1313172.YM304_12580	3.849e-55	215.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158390_k127_2626195_0	1229780.BN381_10084	9.577e-245	773.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,3UW7F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158390_k127_2626195_1	1169161.KB897723_gene4790	1.431e-80	292.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_2626195_6	1229780.BN381_10089	9.727e-33	132.0	COG3255@1|root,COG3255@2|Bacteria,2H0GP@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2626195_8	1476876.JOJO01000003_gene5489	1.232e-12	78.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2626195_2	1313172.YM304_33890	1.201e-57	228.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158390_k127_2626195_7	591158.SSMG_01326	3.259e-26	111.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158390_k127_2626195_4	1313172.YM304_33810	8.374e-38	145.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CMQJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_2634075_0	525909.Afer_0529	3.803e-160	541.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CMP6@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158390_k127_2634075_1	164757.Mjls_4712	6.128e-72	276.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,23435@1762|Mycobacteriaceae	201174|Actinobacteria	EI	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158390_k127_2634075_2	1144342.PMI40_01131	0.0003881	44.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VK3H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Allophanate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR25158390_k127_2636688_12	1313172.YM304_26900	8.903e-105	345.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158390_k127_2636688_6	644283.Micau_4756	2.09e-134	438.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4D9KK@85008|Micromonosporales	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_2636688_35	479432.Sros_8570	1.083e-53	191.0	COG5015@1|root,COG5015@2|Bacteria,2I3I5@201174|Actinobacteria,4EJIN@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2636688_16	1048339.KB913029_gene2112	1.466e-96	334.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158390_k127_2636688_37	1172180.KB911775_gene6246	9.287e-45	175.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158390_k127_2636688_58	1499968.TCA2_3855	4.286e-07	59.0	COG3937@1|root,COG3937@2|Bacteria,1VK6K@1239|Firmicutes,4IR6W@91061|Bacilli,276P6@186822|Paenibacillaceae	91061|Bacilli	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR25158390_k127_2636688_23	1313172.YM304_24870	3.129e-75	261.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CN67@84992|Acidimicrobiia	84992|Acidimicrobiia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158390_k127_2636688_24	1313172.YM304_24880	2.188e-73	258.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CN3D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158390_k127_2636688_4	1313172.YM304_24890	1.059e-154	511.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CMY1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158390_k127_2636688_7	1229780.BN381_290087	9.26e-129	428.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,3UXCS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158390_k127_2636688_54	477641.MODMU_3178	1.786e-15	91.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4ET7I@85013|Frankiales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158390_k127_2636688_33	710111.FraQA3DRAFT_4891	3.318e-57	222.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4ERF4@85013|Frankiales	201174|Actinobacteria	KLT	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158390_k127_2636688_40	1394178.AWOO02000020_gene7390	4.549e-37	155.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4EI2D@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2636688_25	526225.Gobs_3002	3.731e-72	273.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4EURD@85013|Frankiales	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2636688_43	269800.Tfu_2028	2.1e-31	137.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4EG6C@85012|Streptosporangiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2636688_0	1313172.YM304_24900	2.394e-262	822.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CMQD@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158390_k127_2636688_38	1229780.BN381_290082	2.688e-42	168.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,3UWWT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_2636688_47	644283.Micau_5634	7.252e-21	97.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4DK03@85008|Micromonosporales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158390_k127_2636688_11	1313172.YM304_24920	3.108e-106	359.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CMZU@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_2636688_29	356851.JOAN01000021_gene2363	1.069e-62	218.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,4DFP1@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_2636688_53	1151119.KB895491_gene1840	1.167e-15	82.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158390_k127_2636688_9	66373.JOFQ01000008_gene55	2.522e-112	374.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158390_k127_2636688_19	1313172.YM304_24960	1.897e-92	311.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158390_k127_2636688_27	1313172.YM304_24970	1.568e-66	239.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CN9J@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158390_k127_2636688_17	1229780.BN381_290070	4.123e-94	317.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,3UWKC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158390_k127_2636688_36	1229780.BN381_290069	5.876e-47	171.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,3UXJE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158390_k127_2636688_15	1313172.YM304_24990	8.758e-99	352.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CNBS@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158390_k127_2636688_8	649831.L083_2002	1.164e-127	437.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DB3A@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158390_k127_2636688_28	1229780.BN381_290068	3.118e-65	229.0	COG0204@1|root,COG0283@1|root,COG0204@2|Bacteria,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,3UWT7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158390_k127_2636688_34	1313172.YM304_20160	1.19e-56	206.0	COG0204@1|root,COG0204@2|Bacteria,2HG51@201174|Actinobacteria,4CN6X@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158390_k127_2636688_50	390989.JOEG01000001_gene4978	4.958e-18	94.0	COG2132@1|root,COG2132@2|Bacteria,2HU57@201174|Actinobacteria,4DBEA@85008|Micromonosporales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
SRR25158390_k127_2636688_49	644966.Tmar_0494	4.326e-19	95.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
SRR25158390_k127_2636688_56	675635.Psed_2969	4.49e-10	68.0	COG2909@1|root,COG2909@2|Bacteria,2HEY4@201174|Actinobacteria,4E9U2@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158390_k127_2636688_5	1313172.YM304_25520	2.07e-154	499.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CMP7@84992|Acidimicrobiia	84992|Acidimicrobiia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158390_k127_2636688_3	1229780.BN381_40071	1.514e-178	575.0	COG1625@1|root,COG1625@2|Bacteria,2H3RR@201174|Actinobacteria	201174|Actinobacteria	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
SRR25158390_k127_2636688_2	1229780.BN381_40072	5.725e-185	590.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,3UWEY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158390_k127_2636688_26	1229780.BN381_40073	5.282e-70	255.0	COG2208@1|root,COG2208@2|Bacteria,2IHH3@201174|Actinobacteria	201174|Actinobacteria	KT	stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158390_k127_2636688_1	1229780.BN381_40074	9.346e-242	762.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,3UX1Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158390_k127_2636688_18	1122939.ATUD01000001_gene536	1.83e-93	320.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4CSSI@84995|Rubrobacteria	84995|Rubrobacteria	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158390_k127_2636688_59	436229.JOEH01000009_gene4564	7.923e-06	49.0	COG1609@1|root,COG1609@2|Bacteria,2GSWK@201174|Actinobacteria,2NJKA@228398|Streptacidiphilus	201174|Actinobacteria	K	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_2636688_60	455632.SGR_3599	0.0005067	45.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,41BN9@629295|Streptomyces griseus group	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158390_k127_2636688_10	298655.KI912266_gene6305	6.738e-110	359.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4ERJR@85013|Frankiales	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_2636688_45	1463861.JNXE01000002_gene6588	8.245e-27	115.0	2E5N2@1|root,330CX@2|Bacteria,2GUMX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2636688_30	1894.JOER01000065_gene4326	1.178e-60	219.0	COG2306@1|root,COG2306@2|Bacteria,2GQIN@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF402
SRR25158390_k127_2636688_42	591158.SSMG_00040	3.031e-32	135.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158390_k127_2636688_46	1223544.GSI01S_42_00030	2.377e-25	116.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	merB	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB,Pyr_redox_dim
SRR25158390_k127_2636688_44	1229780.BN381_500014	9.61e-30	123.0	COG3339@1|root,COG3339@2|Bacteria,2IR8D@201174|Actinobacteria,3UWQ9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2636688_41	1463820.JOGW01000025_gene2799	2.318e-33	133.0	COG0789@1|root,COG0789@2|Bacteria,2IMEG@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158390_k127_2636688_20	1108045.GORHZ_080_00140	2.214e-90	310.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,4GEAU@85026|Gordoniaceae	201174|Actinobacteria	S	alpha/beta hydrolase fold	dhmA2	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2636688_21	1108045.GORHZ_080_00150	1.716e-85	296.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4GH3C@85026|Gordoniaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_2636688_39	1229780.BN381_130136	1.385e-38	145.0	2EF5E@1|root,338YK@2|Bacteria,2GVSB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2636688_13	1123251.ATWM01000001_gene894	2.435e-103	351.0	COG0079@1|root,COG0079@2|Bacteria,2I2ND@201174|Actinobacteria,4FG89@85021|Intrasporangiaceae	201174|Actinobacteria	E	Aminotransferase class I and II	cobC	GO:0008150,GO:0040007	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,CbiG_C
SRR25158390_k127_2636688_22	1122622.ATWJ01000002_gene838	3.003e-79	280.0	COG1270@1|root,COG1270@2|Bacteria,2GMB8@201174|Actinobacteria,4FEC6@85021|Intrasporangiaceae	201174|Actinobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
SRR25158390_k127_2636688_31	263358.VAB18032_02945	1.671e-60	215.0	COG1865@1|root,COG1865@2|Bacteria,2I8C5@201174|Actinobacteria,4DBX2@85008|Micromonosporales	201174|Actinobacteria	S	Adenosylcobinamide amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CbiZ
SRR25158390_k127_2636688_55	251221.35211609	4.57e-12	75.0	COG5378@1|root,COG5378@2|Bacteria,1G9RD@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_2
SRR25158390_k127_2636688_51	479434.Sthe_2199	1.247e-16	91.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_2636688_57	931627.MycrhDRAFT_2430	5.361e-08	62.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,236KX@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2636688_14	350058.Mvan_1419	2.99e-100	333.0	COG0428@1|root,COG0428@2|Bacteria,2I0ZS@201174|Actinobacteria,237V8@1762|Mycobacteriaceae	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
SRR25158390_k127_2636688_32	994479.GL877879_gene5814	3.656e-60	223.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4DXF7@85010|Pseudonocardiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158390_k127_2640434_1	1229780.BN381_350133	1.6e-125	413.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_2640434_5	219305.MCAG_01383	1.359e-58	205.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,4DDGY@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158390_k127_2640434_3	1229780.BN381_80207	6.951e-67	252.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	ctaG	-	-	ko:K02351,ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
SRR25158390_k127_2640434_6	1229780.BN381_80208	5.437e-44	176.0	COG1999@1|root,COG2847@1|root,COG1999@2|Bacteria,COG2847@2|Bacteria,2GKF0@201174|Actinobacteria	201174|Actinobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158390_k127_2640434_7	1229780.BN381_350095	1.368e-35	151.0	COG0526@1|root,COG0526@2|Bacteria,2H8ZP@201174|Actinobacteria	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2640434_8	1229780.BN381_350094	1.284e-33	136.0	COG1495@1|root,COG1495@2|Bacteria,2HB8T@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the DsbB family	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158390_k127_2640434_0	1121877.JQKF01000001_gene1341	0.0	1300.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CN9K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158390_k127_2640434_4	1122939.ATUD01000008_gene2505	1.077e-62	224.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4CPJ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR25158390_k127_2640434_2	471852.Tcur_3385	2.91e-97	324.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EMUX@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_2640434_9	1120797.KB908270_gene2918	1.913e-27	125.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria,239VE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Death-on-curing protein	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158390_k127_2640434_10	1123024.AUII01000004_gene1691	1.344e-12	69.0	2EM5W@1|root,33EV5@2|Bacteria,2GT38@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_2640434_11	1547437.LL06_20460	2.499e-05	52.0	COG0454@1|root,COG0456@2|Bacteria,1RB0Q@1224|Proteobacteria,2U6TH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158390_k127_264090_6	469378.Ccur_03300	9.852e-25	112.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CUKV@84998|Coriobacteriia	84998|Coriobacteriia	KLT	Kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_264090_2	1169154.KB897779_gene2932	9.589e-98	325.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158390_k127_264090_3	1137269.AZWL01000016_gene331	1.095e-42	158.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the P(II) protein family	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158390_k127_264090_1	1313172.YM304_10110	3.613e-140	459.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CNTR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158390_k127_264090_5	645465.ACUR01000507_gene410	1.343e-32	134.0	COG0745@1|root,COG0745@2|Bacteria,2IQB8@201174|Actinobacteria	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Trans_reg_C
SRR25158390_k127_264090_4	1229780.BN381_60087	4.246e-37	145.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HTH_Crp_2,cNMP_binding
SRR25158390_k127_264090_0	1313172.YM304_39270	2.449e-141	473.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158390_k127_2673324_5	1906.SFRA_06160	2.147e-49	190.0	COG3245@1|root,COG3245@2|Bacteria,2IGG3@201174|Actinobacteria	201174|Actinobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2673324_4	1440053.JOEI01000002_gene3638	1.948e-51	204.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2673324_13	471853.Bcav_1552	8.403e-06	59.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2673324_0	875328.JDM601_2174	4.712e-105	348.0	COG1024@1|root,COG1024@2|Bacteria,2H2U8@201174|Actinobacteria,23AUU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2673324_9	1122609.AUGT01000009_gene3397	3.566e-24	102.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4DRCK@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2673324_10	298655.KI912267_gene7635	1.962e-15	84.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4EVBN@85013|Frankiales	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_2673324_2	1448389.BAVQ01000003_gene3509	8.236e-68	242.0	arCOG10456@1|root,2ZA6T@2|Bacteria,2IIHU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2673324_16	1122138.AQUZ01000036_gene5413	0.0001861	53.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4DPJZ@85009|Propionibacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_2673324_11	1380347.JNII01000007_gene62	3.757e-08	65.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4ETU7@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_2673324_1	1380347.JNII01000007_gene61	1.988e-80	280.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EUFW@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2673324_7	930171.Asphe3_07380	6.321e-40	153.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,1WAK3@1268|Micrococcaceae	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_2673324_3	1122176.KB903531_gene3019	7.227e-53	202.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_2673324_6	298653.Franean1_4861	1.034e-47	192.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_2673324_12	1463855.JOHV01000006_gene4918	2.558e-06	56.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158390_k127_2673324_14	1240349.ANGC01000017_gene4743	2.129e-05	53.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria,4FW42@85025|Nocardiaceae	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158390_k127_2673324_15	710685.MycrhN_5791	4.02e-05	49.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria,236K6@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158390_k127_2673324_8	644283.Micau_1132	2.656e-26	112.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4D941@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_2695165_4	1173022.Cri9333_1305	1.098e-54	195.0	COG0605@1|root,COG0605@2|Bacteria,1G0N2@1117|Cyanobacteria,1H8FH@1150|Oscillatoriales	1117|Cyanobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158390_k127_2695165_6	1313172.YM304_37920	7.163e-21	98.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158390_k127_2695165_5	1229780.BN381_60053	2.056e-52	191.0	COG0406@1|root,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,3UWZM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	-	ko:K15640	-	-	-	-	ko00000	-	-	-	His_Phos_1
SRR25158390_k127_2695165_7	491915.Aflv_0378	2.983e-19	93.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,21WSK@150247|Anoxybacillus	91061|Bacilli	T	Prokaryotic dksA/traR C4-type zinc finger	yteA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158390_k127_2695165_0	1122247.C731_0728	6.118e-217	686.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,232FY@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD19_2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2695165_1	298654.FraEuI1c_4744	6.299e-92	313.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4ESAR@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD, ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_2695165_2	1229780.BN381_130288	7.222e-89	312.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,3UWVR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	ABC 3 transport family	mntB	-	-	ko:K09819,ko:K11602,ko:K19975,ko:K19976	ko02010,ko02020,map02010,map02020	M00243,M00316,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.1,3.A.1.15.15	-	-	ABC-3
SRR25158390_k127_2695165_3	1229780.BN381_130287	2.703e-74	254.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,3UXDF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.35	ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
SRR25158390_k127_2720426_1	469371.Tbis_2251	1.782e-74	256.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DY8C@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158390_k127_2720426_2	749927.AMED_8473	2.755e-64	238.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DXY0@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158390_k127_2720426_3	1114959.SZMC14600_04772	5.64e-38	165.0	COG0730@1|root,COG0730@2|Bacteria,2IIY7@201174|Actinobacteria,4E3NW@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_2720426_0	1122611.KB903965_gene4970	6.208e-105	354.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2720426_4	397278.JOJN01000003_gene1918	8.471e-32	134.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DPXT@85009|Propionibacteriales	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
SRR25158390_k127_2720426_5	1122611.KB904018_gene7050	3.686e-11	75.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4EN04@85012|Streptosporangiales	201174|Actinobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
SRR25158390_k127_2728497_3	1463825.JNXC01000022_gene553	2.282e-09	66.0	COG0824@1|root,COG0824@2|Bacteria,2IINH@201174|Actinobacteria,4E74I@85010|Pseudonocardiales	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158390_k127_2728497_1	1150864.MILUP08_43219	7.281e-75	277.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_2728497_4	1410668.JNKC01000016_gene993	6.446e-05	47.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2728497_2	649743.HMPREF0972_00987	7.905e-51	202.0	COG2931@1|root,COG4842@1|root,COG2931@2|Bacteria,COG4842@2|Bacteria,2GKS7@201174|Actinobacteria,4D74A@85005|Actinomycetales	201174|Actinobacteria	Q	Effector protein	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
SRR25158390_k127_2728497_0	1313172.YM304_18300	1.53e-93	325.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CN55@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
SRR25158390_k127_2730889_3	1229780.BN381_50151	5.853e-40	149.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,3UWE6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158390_k127_2730889_0	1229780.BN381_50152	4.723e-149	496.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,3UWAF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158390_k127_2730889_1	211114.JOEF01000001_gene7618	9.267e-121	396.0	COG0182@1|root,COG0182@2|Bacteria,2GJJA@201174|Actinobacteria,4DZKT@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,IF-2B
SRR25158390_k127_2730889_2	1127134.NOCYR_1632	2.255e-47	179.0	2C9IE@1|root,31AT3@2|Bacteria,2IM6M@201174|Actinobacteria,4G1K7@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158390_k127_2739788_2	1313172.YM304_07800	2.694e-80	281.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158390_k127_2739788_3	1313172.YM304_09000	6.324e-58	215.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158390_k127_2739788_5	266117.Rxyl_0667	3.428e-18	100.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_2739788_4	1313172.YM304_09020	1.755e-50	184.0	COG0314@1|root,COG0314@2|Bacteria,2HG21@201174|Actinobacteria,4CN80@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158390_k127_2739788_0	1313172.YM304_09040	3.294e-144	468.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158390_k127_2739788_1	28444.JODQ01000015_gene1613	4.429e-122	404.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4EHMR@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
SRR25158390_k127_2759648_3	1048339.KB913029_gene4706	1.528e-41	169.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4EUGA@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_2759648_6	996637.SGM_1454	8.828e-09	63.0	COG3311@1|root,COG3311@2|Bacteria,2IRQ7@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_2759648_0	1385520.N802_09685	1.787e-144	471.0	COG0484@1|root,COG0484@2|Bacteria,2GIXJ@201174|Actinobacteria,4FFJX@85021|Intrasporangiaceae	201174|Actinobacteria	O	Replication initiator protein	repSA	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2759648_1	446462.Amir_3639	6.207e-85	304.0	COG0494@1|root,COG0494@2|Bacteria,2HNEM@201174|Actinobacteria,4E09R@85010|Pseudonocardiales	201174|Actinobacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2759648_2	414996.IL38_16425	6.157e-47	173.0	COG1917@1|root,COG1917@2|Bacteria,2IHMX@201174|Actinobacteria	201174|Actinobacteria	U	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2759648_4	1032480.MLP_24830	5.786e-24	105.0	COG1595@1|root,COG1595@2|Bacteria,2HG34@201174|Actinobacteria,4DWA5@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2771551_1	1229780.BN381_50160	9.481e-184	580.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,3UWF0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158390_k127_2771551_20	45157.CMI238CT	1.172e-35	141.0	COG0054@1|root,KOG3243@2759|Eukaryota	2759|Eukaryota	H	6,7-dimethyl-8-ribityllumazine synthase activity	RIB4	GO:0000906,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019842,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902444	2.5.1.78,2.5.1.9,2.6.1.16	ko:K00793,ko:K00794,ko:K00820	ko00250,ko00520,ko00740,ko01100,ko01110,ko01130,ko04931,map00250,map00520,map00740,map01100,map01110,map01130,map04931	M00125	R00066,R00768,R04457	RC00010,RC00163,RC00958,RC00960,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DMRL_synthase
SRR25158390_k127_2771551_7	1313172.YM304_20600	1.503e-116	386.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CMTS@84992|Acidimicrobiia	84992|Acidimicrobiia	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158390_k127_2771551_21	1313172.YM304_20630	1.523e-17	89.0	2FH85@1|root,3492H@2|Bacteria,2H8HQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2771551_13	1313172.YM304_20650	1.189e-69	242.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CMZR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158390_k127_2771551_22	656024.FsymDg_3290	4.604e-14	77.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4ETHR@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158390_k127_2771551_16	525909.Afer_1676	5.159e-45	166.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CN4X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158390_k127_2771551_17	219305.MCAG_04915	1.143e-43	171.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4DAJB@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158390_k127_2771551_10	1121877.JQKF01000023_gene2231	5.829e-93	327.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CMPG@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158390_k127_2771551_0	1229780.BN381_290127	5.112e-216	702.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,3UW7Y@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158390_k127_2771551_6	1229780.BN381_290123	1.516e-118	390.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,3UWGI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158390_k127_2771551_8	1161401.ASJA01000022_gene125	7.791e-101	366.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,43W6I@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158390_k127_2771551_9	1313172.YM304_20800	2.943e-99	350.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158390_k127_2771551_5	1313172.YM304_20810	4.679e-137	455.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CMTH@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_2771551_11	1229780.BN381_290120	6.505e-86	308.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,3UWID@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.6	ko:K00611,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158390_k127_2771551_14	1229780.BN381_290119	1.192e-53	201.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,3UWW0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Arginine repressor, DNA binding domain	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158390_k127_2771551_3	1161401.ASJA01000022_gene121	2.174e-168	539.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,43WGQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158390_k127_2771551_2	1313172.YM304_20840	2.108e-178	589.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CMW7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158390_k127_2771551_12	1163409.UUA_00865	1.407e-79	271.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria,1X6BU@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158390_k127_2771551_18	1229780.BN381_30027	2.034e-40	164.0	COG1051@1|root,COG1051@2|Bacteria,2I2SX@201174|Actinobacteria,3UXQN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_2771551_4	1128421.JAGA01000003_gene3003	1.001e-153	491.0	COG1089@1|root,COG1089@2|Bacteria,2NNM2@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_2771551_19	1128421.JAGA01000003_gene3004	2.898e-39	152.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	FHIPEP,HTH_3,HTH_31
SRR25158390_k127_2771551_15	1313172.YM304_20900	1.698e-46	183.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CMT0@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
SRR25158390_k127_278020_1	1313172.YM304_07620	6.734e-189	598.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_278020_15	367299.JOEE01000005_gene3530	1.587e-32	147.0	2EJZM@1|root,33DQ6@2|Bacteria,2IBYK@201174|Actinobacteria,4FEH6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_278020_12	1313172.YM304_07630	8.363e-35	136.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4CP4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_278020_8	525909.Afer_0329	3.504e-76	263.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CNR1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD_N
SRR25158390_k127_278020_17	278957.ABEA03000195_gene543	5.031e-09	60.0	COG1826@1|root,COG1826@2|Bacteria,46WPX@74201|Verrucomicrobia,3K8HZ@414999|Opitutae	414999|Opitutae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158390_k127_278020_14	1313172.YM304_07660	1.044e-32	129.0	2CC1Y@1|root,32TCV@2|Bacteria,2HGD4@201174|Actinobacteria,4CNAQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_278020_7	1229780.BN381_130087	5.774e-80	289.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,3UWP8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_278020_13	1313172.YM304_07670	2.944e-33	133.0	2FBA6@1|root,343GA@2|Bacteria,2H78Y@201174|Actinobacteria,4CN8Z@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_278020_0	1229780.BN381_130089	3.388e-253	798.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,3UWBN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158390_k127_278020_9	580340.Tlie_0063	5.643e-76	270.0	COG1322@1|root,COG1322@2|Bacteria,3T9XJ@508458|Synergistetes	508458|Synergistetes	S	PFAM RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158390_k127_278020_3	1313172.YM304_07690	1.249e-96	326.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158390_k127_278020_4	1313172.YM304_07700	6.882e-96	325.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_278020_5	1313172.YM304_07710	7.161e-82	283.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria	201174|Actinobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_278020_2	446470.Snas_2214	3.341e-100	359.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EXWB@85014|Glycomycetales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158390_k127_278020_16	196162.Noca_4044	2.429e-19	96.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4DQEB@85009|Propionibacteriales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158390_k127_278020_10	644283.Micau_2023	2.671e-53	201.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4DGXT@85008|Micromonosporales	201174|Actinobacteria	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158390_k127_278020_6	1313172.YM304_07740	6.69e-81	285.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CMZJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158390_k127_278020_11	1229780.BN381_30042	2.018e-46	183.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,3UWH9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2798293_7	479433.Caci_5352	1.571e-107	379.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_2798293_1	1123320.KB889747_gene7183	6.03e-177	573.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRR25158390_k127_2798293_12	1380356.JNIK01000016_gene3661	1.204e-39	168.0	2E9QE@1|root,333WR@2|Bacteria,2I2DC@201174|Actinobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2798293_11	469383.Cwoe_1406	8.811e-44	162.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,4CT0B@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_2798293_2	469383.Cwoe_3324	1.86e-176	561.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4CRBD@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2798293_13	1192034.CAP_1262	1.314e-36	153.0	COG3568@1|root,COG3568@2|Bacteria,1NJUY@1224|Proteobacteria,432E7@68525|delta/epsilon subdivisions,2WXI5@28221|Deltaproteobacteria,2YVNS@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_2798293_8	1194972.MVAC_12718	2.172e-75	260.0	COG0662@1|root,COG0662@2|Bacteria,2I41N@201174|Actinobacteria,2380V@1762|Mycobacteriaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_2798293_0	1123320.KB889585_gene1895	3.055e-199	628.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2798293_4	1123320.KB889585_gene1894	8.173e-141	476.0	COG1804@1|root,COG1804@2|Bacteria,2IEU2@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_2798293_9	479433.Caci_5358	9.41e-72	259.0	COG2030@1|root,COG2030@2|Bacteria,2ICZR@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158390_k127_2798293_10	479433.Caci_5359	2.426e-56	214.0	COG2030@1|root,COG2030@2|Bacteria,2IPFP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_2798293_5	1123320.KB889585_gene1891	2.311e-127	421.0	COG1960@1|root,COG1960@2|Bacteria,2I8MN@201174|Actinobacteria	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158390_k127_2798293_6	680198.SCAB_51661	2.041e-109	360.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158390_k127_2798293_3	1229780.BN381_50061	5.694e-152	496.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,3UWHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158390_k127_2832261_8	1229780.BN381_60042	2.771e-80	276.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,3UWP6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158390_k127_2832261_3	469383.Cwoe_5880	3.006e-132	447.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CPJJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158390_k127_2832261_14	326423.RBAM_009500	5.17e-38	164.0	COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,1ZEV6@1386|Bacillus	91061|Bacilli	S	hydrolase	yhcW	GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158390_k127_2832261_13	408672.NBCG_01835	7.747e-44	180.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4DRHN@85009|Propionibacteriales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_2832261_6	298654.FraEuI1c_3249	1.507e-99	331.0	COG0411@1|root,COG0411@2|Bacteria,2IJ5Y@201174|Actinobacteria,4EV5P@85013|Frankiales	201174|Actinobacteria	E	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_2832261_7	1313172.YM304_30760	3.28e-85	290.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_2832261_9	66874.JOFS01000005_gene3824	1.146e-65	244.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_2832261_10	1229780.BN381_130108	4.08e-63	243.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,3UXF4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_2832261_12	1206732.BAGD01000113_gene5078	5.537e-56	222.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4FZUX@85025|Nocardiaceae	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_2832261_2	1229780.BN381_60037	2.408e-140	456.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,3UW8S@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158390_k127_2832261_11	1229780.BN381_500002	3.423e-62	231.0	COG3568@1|root,COG3568@2|Bacteria,2HQV4@201174|Actinobacteria	201174|Actinobacteria	M	Jacalin-like lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Jacalin
SRR25158390_k127_2832261_1	1313172.YM304_37790	2.13e-148	487.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CMTZ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_2832261_16	926562.Oweho_0994	2.045e-05	57.0	2ENVG@1|root,33GGJ@2|Bacteria,4P2K9@976|Bacteroidetes,1I8MZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2832261_4	314278.NB231_09548	6.815e-122	412.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRR25158390_k127_2832261_5	471852.Tcur_0003	2.838e-114	376.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4EHS7@85012|Streptosporangiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158390_k127_2832261_0	1150864.MILUP08_43634	9.813e-155	510.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4D94H@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158390_k127_2832261_15	1313172.YM304_33880	2.022e-30	135.0	COG0682@1|root,COG0682@2|Bacteria,2HGGR@201174|Actinobacteria,4CNDX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158390_k127_2856650_1	1157943.KB892705_gene2248	1.924e-176	563.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158390_k127_2856650_15	1463934.JOCF01000088_gene407	4.819e-26	115.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Pyridox_ox_2
SRR25158390_k127_2856650_14	2074.JNYD01000002_gene5605	1.99e-30	126.0	COG3467@1|root,COG3467@2|Bacteria,2GQIA@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158390_k127_2856650_2	1123023.JIAI01000028_gene4512	6.45e-146	479.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4E8B0@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
SRR25158390_k127_2856650_5	1120936.KB907209_gene1288	6.016e-107	367.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4EHHI@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_2856650_12	1313172.YM304_03960	1.507e-39	151.0	COG1959@1|root,COG1959@2|Bacteria,2GS0E@201174|Actinobacteria,4CNRF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158390_k127_2856650_8	1229780.BN381_70127	6.77e-78	270.0	294HY@1|root,2ZRXK@2|Bacteria	2|Bacteria	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158390_k127_2856650_7	656024.FsymDg_0692	1.013e-85	300.0	COG0392@1|root,COG0392@2|Bacteria,2GZ8W@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205,ko:K20468	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158390_k127_2856650_3	882082.SaccyDRAFT_2312	4.663e-130	439.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4DXYD@85010|Pseudonocardiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158390_k127_2856650_10	266117.Rxyl_0659	7.836e-61	216.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4CQQD@84995|Rubrobacteria	84995|Rubrobacteria	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158390_k127_2856650_17	344747.PM8797T_22863	4.438e-22	101.0	COG0530@1|root,COG0530@2|Bacteria,2J283@203682|Planctomycetes	203682|Planctomycetes	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158390_k127_2856650_13	756272.Plabr_4467	1.768e-35	142.0	COG0530@1|root,COG0530@2|Bacteria,2J283@203682|Planctomycetes	203682|Planctomycetes	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158390_k127_2856650_0	1229780.BN381_290124	1.939e-190	616.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,3UWDK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_2856650_11	1089545.KB913037_gene7697	1.437e-53	197.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_2856650_9	2002.JOEQ01000008_gene976	9.066e-68	236.0	COG5516@1|root,COG5516@2|Bacteria,2GP70@201174|Actinobacteria,4EQ62@85012|Streptosporangiales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158390_k127_2856650_16	500635.MITSMUL_03605	1.897e-24	115.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4H2XP@909932|Negativicutes	909932|Negativicutes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158390_k127_2856650_6	1191523.MROS_2662	4.82e-92	323.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158390_k127_2856650_4	1184607.AUCHE_05_04270	1.126e-114	376.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158390_k127_2911186_8	743719.PaelaDRAFT_4374	5.351e-10	68.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC0R@91061|Bacilli,26R3U@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369,1.1.1.371	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951,R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_2911186_3	1449976.KALB_3200	5.332e-100	334.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4E5P5@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2911186_2	1313172.YM304_22360	1.448e-173	560.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CNMV@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158390_k127_2911186_1	1211815.CBYP010000063_gene1912	8.284e-278	880.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158390_k127_2911186_0	1211815.CBYP010000063_gene1911	1.129e-308	962.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4EU7X@85013|Frankiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158390_k127_2911186_6	298654.FraEuI1c_2878	4.906e-71	270.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR7	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158390_k127_2911186_5	1211815.CBYP010000063_gene1909	4.25e-96	330.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Wyosine base formation	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
SRR25158390_k127_2911186_4	298654.FraEuI1c_2880	3.88e-96	325.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4ESJA@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2911186_7	1150599.MPHLEI_03733	5.862e-55	199.0	COG1545@1|root,COG1545@2|Bacteria,2IH6P@201174|Actinobacteria,23998@1762|Mycobacteriaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_2911186_9	1206730.BAGA01000072_gene1988	5.261e-06	52.0	COG0183@1|root,COG0183@2|Bacteria,2IDW8@201174|Actinobacteria,4G026@85025|Nocardiaceae	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_2951524_4	208439.AJAP_01390	2.668e-13	72.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4E5G5@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158390_k127_2951524_0	469383.Cwoe_1045	1.103e-167	562.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_2951524_1	66869.JNXG01000010_gene676	2.267e-138	455.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,41A5A@629295|Streptomyces griseus group	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158390_k127_2951524_2	1146883.BLASA_3115	1.147e-72	255.0	COG1597@1|root,COG1597@2|Bacteria,2GNTZ@201174|Actinobacteria	201174|Actinobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158390_k127_2951524_3	477641.MODMU_1223	2.333e-24	116.0	2D3F0@1|root,32TEU@2|Bacteria,2IDGD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2951524_5	243090.RB8816	3.338e-11	76.0	COG1595@1|root,COG1595@2|Bacteria,2IZMT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_2956221_6	1313172.YM304_09910	1.086e-06	50.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CMXI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158390_k127_2956221_1	1229780.BN381_310072	4.251e-111	369.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,3UWMR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158390_k127_2956221_0	35754.JNYJ01000044_gene4355	2.811e-132	458.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DHDF@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158390_k127_2956221_4	1035308.AQYY01000001_gene3501	9.019e-64	231.0	COG5032@1|root,COG5032@2|Bacteria	2|Bacteria	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
SRR25158390_k127_2956221_5	1121877.JQKF01000069_gene1260	1.426e-26	126.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4CN9I@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158390_k127_2956221_3	136273.GY22_04980	1.625e-72	251.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,1W9CE@1268|Micrococcaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_2956221_2	1380347.JNII01000006_gene1464	3.146e-86	297.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4ERCZ@85013|Frankiales	201174|Actinobacteria	L	uracil-DNA glycosylase	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_2978712_1	1313172.YM304_10860	1.144e-117	387.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CMV6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158390_k127_2978712_5	1313172.YM304_12290	1.211e-60	221.0	COG0500@1|root,COG0500@2|Bacteria,2I3YC@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_2978712_7	269800.Tfu_2497	1.939e-20	105.0	COG4223@1|root,COG4223@2|Bacteria,2I390@201174|Actinobacteria,4EJ5Z@85012|Streptosporangiales	201174|Actinobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158390_k127_2978712_8	326424.FRAAL1299	1.031e-19	103.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria,4EVKQ@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4350)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158390_k127_2978712_0	1229780.BN381_10074	3.8e-137	452.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,3UX6H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158390_k127_2978712_2	1229780.BN381_10075	5.806e-117	404.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria,3UXC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR25158390_k127_2978712_3	1313172.YM304_12530	6.204e-90	308.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158390_k127_2978712_6	1313172.YM304_12540	2.644e-41	165.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria	201174|Actinobacteria	A	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_2978712_4	1229780.BN381_290011	9.697e-76	260.0	COG2375@1|root,COG2375@2|Bacteria,2HEWI@201174|Actinobacteria,3UWVN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Siderophore-interacting FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
SRR25158390_k127_2985020_19	1158050.KB895474_gene2838	4.3e-112	373.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158390_k127_2985020_39	105422.BBPM01000015_gene2053	4.662e-82	299.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,2I36T@201174|Actinobacteria,2NNH8@228398|Streptacidiphilus	201174|Actinobacteria	M	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_2985020_46	1137269.AZWL01000006_gene6750	8.168e-63	233.0	28KB1@1|root,2Z9Y5@2|Bacteria,2GM37@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2985020_17	1121926.AXWO01000008_gene2920	3.629e-121	400.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4EZBG@85014|Glycomycetales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158390_k127_2985020_48	953739.SVEN_6511	1.412e-49	198.0	COG3222@1|root,COG3222@2|Bacteria,2GN3B@201174|Actinobacteria	201174|Actinobacteria	Q	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SRR25158390_k127_2985020_51	909613.UO65_4994	1.785e-41	170.0	COG0500@1|root,COG0500@2|Bacteria,2I2R3@201174|Actinobacteria,4E3W2@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158390_k127_2985020_38	1313172.YM304_09090	2.395e-85	290.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria,4CN8Q@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158390_k127_2985020_7	1229780.BN381_150116	2.245e-145	471.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria,3UX92@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
SRR25158390_k127_2985020_34	471852.Tcur_3659	4.165e-88	306.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4EH41@85012|Streptosporangiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_2985020_4	1229780.BN381_150118	2.851e-176	561.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,3UX6F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2985020_62	1150864.MILUP08_42946	4.192e-25	121.0	COG0443@1|root,COG0443@2|Bacteria,2GNTE@201174|Actinobacteria,4DIRK@85008|Micromonosporales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
SRR25158390_k127_2985020_50	1313172.YM304_09310	2.579e-44	171.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158390_k127_2985020_18	1229780.BN381_100020	1.461e-117	413.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,3UWR9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158390_k127_2985020_53	1313172.YM304_09330	3.403e-37	152.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158390_k127_2985020_26	47763.JNZA01000022_gene2725	5.725e-99	339.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158390_k127_2985020_36	1229780.BN381_100024	1.055e-86	311.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,3UWVK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158390_k127_2985020_13	479433.Caci_6783	5.478e-130	443.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158390_k127_2985020_8	1122611.KB903939_gene373	3.894e-137	462.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4EH5T@85012|Streptosporangiales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158390_k127_2985020_30	1121272.KB903254_gene6728	4.597e-90	318.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DCIX@85008|Micromonosporales	201174|Actinobacteria	P	TOBE domain	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158390_k127_2985020_31	1313172.YM304_15190	2.506e-89	307.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158390_k127_2985020_20	1313172.YM304_15180	8.719e-105	360.0	COG1178@1|root,COG1178@2|Bacteria,2HFVM@201174|Actinobacteria,4CP3M@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158390_k127_2985020_32	1313172.YM304_09420	4.915e-89	304.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158390_k127_2985020_27	1464048.JNZS01000008_gene6085	2.276e-96	330.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria,4D9BI@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K13633	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
SRR25158390_k127_2985020_47	1380347.JNII01000005_gene3882	2.424e-51	186.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4EVK6@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2985020_57	590998.Celf_3649	7.76e-31	128.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158390_k127_2985020_9	518766.Rmar_2662	2.734e-136	447.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1FJ2X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_2985020_60	1211815.CBYP010000066_gene1591	2.081e-28	131.0	2C6J1@1|root,33H0F@2|Bacteria,2IMXS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2985020_29	1206725.BAFU01000068_gene5714	5.32e-92	311.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,4FY6B@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2985020_49	479435.Kfla_0352	1.835e-48	177.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4DSET@85009|Propionibacteriales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_2985020_68	1122939.ATUD01000013_gene844	7.035e-05	49.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_2985020_59	1229780.BN381_350092	6.374e-29	120.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	ksi	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
SRR25158390_k127_2985020_52	1229780.BN381_130142	1.029e-40	152.0	COG2337@1|root,COG2337@2|Bacteria,2IR5D@201174|Actinobacteria	201174|Actinobacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_2985020_6	1048339.KB913029_gene2528	2.312e-169	567.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_2985020_22	1380346.JNIH01000036_gene311	6.247e-104	344.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2985020_58	1123024.AUII01000006_gene4577	3.8e-29	122.0	COG1396@1|root,COG1396@2|Bacteria,2GPQW@201174|Actinobacteria,4EC3K@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158390_k127_2985020_24	1896.JOAU01000037_gene1768	1.649e-103	348.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_2985020_3	1313172.YM304_12820	7.539e-177	568.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CMU6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_2985020_43	1313172.YM304_35100	1.815e-64	229.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158390_k127_2985020_54	369723.Strop_2301	3.456e-34	151.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4DENZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_2985020_33	1394178.AWOO02000032_gene4932	3.058e-88	299.0	COG0842@1|root,COG0842@2|Bacteria,2IHJH@201174|Actinobacteria,4ENXS@85012|Streptosporangiales	201174|Actinobacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2985020_10	1394178.AWOO02000032_gene4931	1.289e-134	443.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ENIC@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2985020_23	1380356.JNIK01000021_gene4516	7.575e-104	355.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4EVWX@85013|Frankiales	201174|Actinobacteria	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_2985020_25	518766.Rmar_0424	4.985e-99	347.0	COG0025@1|root,COG0569@1|root,COG1762@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,4PKJ5@976|Bacteroidetes,1FIVS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158390_k127_2985020_1	390989.JOEG01000012_gene3403	8.821e-222	710.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_2985020_21	28444.JODQ01000017_gene6541	5.301e-104	353.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4EG3S@85012|Streptosporangiales	201174|Actinobacteria	L	Calcineurin-like phosphoesterase superfamily domain	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
SRR25158390_k127_2985020_15	390989.JOEG01000012_gene3414	6.751e-123	436.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DA3T@85008|Micromonosporales	201174|Actinobacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
SRR25158390_k127_2985020_40	1089545.KB913037_gene6192	1.148e-75	270.0	COG2380@1|root,COG2380@2|Bacteria,2I8F9@201174|Actinobacteria,4E8J3@85010|Pseudonocardiales	201174|Actinobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2985020_5	1229780.BN381_90087	2.769e-170	561.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,3UWE3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158390_k127_2985020_55	1229780.BN381_130173	1.597e-33	134.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Nfu_N,NifU
SRR25158390_k127_2985020_64	1229780.BN381_130173	1.134e-16	80.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Nfu_N,NifU
SRR25158390_k127_2985020_0	1229780.BN381_90078	1.391e-248	786.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,3UW82@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158390_k127_2985020_42	1217720.ALOX01000087_gene3033	6.449e-71	259.0	COG4427@1|root,COG4427@2|Bacteria,1R4EV@1224|Proteobacteria,2TRVP@28211|Alphaproteobacteria,2JWMB@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158390_k127_2985020_44	1313172.YM304_10870	3.025e-63	241.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158390_k127_2985020_45	1229780.BN381_90077	3.651e-63	231.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158390_k127_2985020_67	1283299.AUKG01000003_gene576	4.433e-05	55.0	2DPU0@1|root,333DA@2|Bacteria,2HPPH@201174|Actinobacteria,4CR26@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2985020_56	1313172.YM304_10880	1.083e-31	144.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_2985020_2	1229780.BN381_90073	6.95e-209	667.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158390_k127_2985020_11	1313172.YM304_10900	2.088e-133	461.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158390_k127_2985020_16	1313172.YM304_10900	8.459e-122	406.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158390_k127_2985020_37	1313172.YM304_10970	1.386e-86	294.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158390_k127_2985020_35	1304880.JAGB01000001_gene849	1.829e-87	298.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158390_k127_2985020_63	1134445.AJJM01000022_gene4229	8.689e-21	106.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158390_k127_2985020_61	1313172.YM304_35160	3.222e-27	118.0	COG0344@1|root,COG0344@2|Bacteria,2IF8Y@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158390_k127_2985020_14	1229780.BN381_90066	6.259e-124	407.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria,3UWE1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158390_k127_2985020_28	1229780.BN381_90065	3.396e-96	334.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,3UXDG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158390_k127_2985020_12	1229780.BN381_90064	2.292e-132	431.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,3UX2T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Molybdenum Cofactor Synthesis C	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158390_k127_2985020_41	1121877.JQKF01000003_gene1581	1.131e-71	255.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158390_k127_2986698_0	40571.JOEA01000002_gene4887	1.493e-96	327.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DZBC@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator with HTH domain and aminotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_2986698_2	931626.Awo_c20220	8.233e-50	190.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158390_k127_2986698_1	1114856.C496_19525	1.448e-72	255.0	COG2897@1|root,arCOG02019@2157|Archaea,2XW8Q@28890|Euryarchaeota,23UHH@183963|Halobacteria	183963|Halobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158390_k127_2986698_3	710686.Mycsm_03199	1.592e-15	79.0	COG1309@1|root,COG1309@2|Bacteria,2I0IN@201174|Actinobacteria,23CQ9@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2991536_2	1229780.BN381_170035	1.639e-130	430.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_2991536_0	1229780.BN381_170034	4.573e-180	581.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,3UWFB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158390_k127_2991536_6	1229780.BN381_170009	3.671e-46	172.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,3UWZ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Ferric uptake regulator family	catR	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158390_k127_2991536_4	1121877.JQKF01000010_gene733	7.552e-72	246.0	COG1592@1|root,COG1592@2|Bacteria,2HH04@201174|Actinobacteria,4CP0H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2991536_1	1121877.JQKF01000010_gene732	5.195e-131	434.0	COG0247@1|root,COG0247@2|Bacteria,2HGN8@201174|Actinobacteria,4CNP8@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
SRR25158390_k127_2991536_5	1229780.BN381_170007	1.837e-63	231.0	COG0247@1|root,COG0247@2|Bacteria,2GVNV@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
SRR25158390_k127_2991536_9	1229780.BN381_170006	6.699e-20	96.0	2CC1Y@1|root,32YV9@2|Bacteria,2HGFB@201174|Actinobacteria,3UXMX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Transcription factor WhiB	-	-	-	-	-	-	-	-	-	-	-	-	Whib
SRR25158390_k127_2991536_3	1122132.AQYH01000010_gene4242	5.189e-86	305.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,4B71E@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158390_k127_2991536_8	1122611.KB903940_gene1815	2.575e-22	113.0	COG1309@1|root,COG1309@2|Bacteria,2GUIR@201174|Actinobacteria,4EM84@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2991536_7	1283299.AUKG01000003_gene598	4.243e-25	106.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4CQQR@84995|Rubrobacteria	84995|Rubrobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_3014329_4	1216976.AX27061_0537	1.326e-66	240.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2VIDZ@28216|Betaproteobacteria,3T2AT@506|Alcaligenaceae	28216|Betaproteobacteria	P	COG4597 ABC-type amino acid transport system, permease component	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158390_k127_3014329_3	1128421.JAGA01000002_gene1954	3.183e-69	262.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	-	-	-	ko:K02029,ko:K09971	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158390_k127_3014329_2	1313172.YM304_29160	2.433e-107	375.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CP57@84992|Acidimicrobiia	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10041	ko02010,map02010	M00228,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
SRR25158390_k127_3014329_7	483219.LILAB_00630	6.601e-08	63.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2YY3U@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
SRR25158390_k127_3014329_0	1449353.JQMQ01000005_gene5516	2.151e-190	601.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,2NGFF@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_3014329_8	1026970.XP_008851354.1	0.0008692	46.0	KOG2842@1|root,KOG2842@2759|Eukaryota,38EW2@33154|Opisthokonta,3B9K5@33208|Metazoa,3CYQ8@33213|Bilateria,4889S@7711|Chordata,496BT@7742|Vertebrata,3JBM7@40674|Mammalia,35I8E@314146|Euarchontoglires,4PZIK@9989|Rodentia	33208|Metazoa	Z	Interferon-related developmental regulator (IFRD)	IFRD2	-	-	-	-	-	-	-	-	-	-	-	IFRD,IFRD_C
SRR25158390_k127_3014329_6	1032480.MLP_45100	1.304e-29	129.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DMZZ@85009|Propionibacteriales	201174|Actinobacteria	M	G5	rlpA	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158390_k127_3014329_1	1229780.BN381_310013	8.006e-136	441.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3014329_5	68199.JNZO01000046_gene6512	1.854e-53	199.0	2BVHN@1|root,332R2@2|Bacteria,2IFVR@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3019013_9	1313172.YM304_00110	1.173e-17	88.0	COG1748@1|root,COG1748@2|Bacteria,2H8X8@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3019013_2	1134445.AJJM01000056_gene2186	4.455e-97	329.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158390_k127_3019013_5	1229780.BN381_100201	8.69e-83	289.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,3UWIT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158390_k127_3019013_8	525909.Afer_1728	2.083e-44	165.0	COG0764@1|root,COG0764@2|Bacteria,2GQWT@201174|Actinobacteria,4CN5K@84992|Acidimicrobiia	84992|Acidimicrobiia	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158390_k127_3019013_3	35754.JNYJ01000035_gene3877	6.684e-94	331.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4D93E@85008|Micromonosporales	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208,ko:K11611	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_3019013_1	1313172.YM304_21250	6.35e-109	385.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMQK@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158390_k127_3019013_0	1463854.JOHT01000007_gene3381	4.012e-126	417.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158390_k127_3019013_10	1121877.JQKF01000021_gene2200	3.51e-14	79.0	COG0236@1|root,COG0236@2|Bacteria,2HGA0@201174|Actinobacteria,4CN8U@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158390_k127_3019013_6	33876.JNXY01000009_gene9005	3.716e-61	227.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4DAAN@85008|Micromonosporales	201174|Actinobacteria	IQ	reductase	fabG1	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059,ko:K11610	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_3019013_4	1128421.JAGA01000002_gene1728	1.707e-87	305.0	COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158390_k127_3019013_11	1121877.JQKF01000021_gene2197	2.435e-09	68.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158390_k127_3019013_7	1313172.YM304_21340	2.044e-46	175.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158390_k127_3033132_0	1184607.AUCHE_05_04270	0.0	1242.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158390_k127_3033132_8	1206733.BAGC01000004_gene5881	2.531e-25	115.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_3033132_7	1123229.AUBC01000006_gene989	2.101e-63	228.0	COG0177@1|root,COG0177@2|Bacteria,1N2HB@1224|Proteobacteria,2U8WA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3033132_3	469383.Cwoe_3031	1.42e-113	379.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CRRF@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158390_k127_3033132_5	1120950.KB892782_gene280	3.196e-94	331.0	COG3416@1|root,COG3416@2|Bacteria,2HVVA@201174|Actinobacteria,4DQRT@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_3033132_9	1463921.JODF01000095_gene5138	2.013e-24	107.0	2DPD4@1|root,331JQ@2|Bacteria,2ISF8@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
SRR25158390_k127_3033132_4	1214242.B446_02480	1.799e-100	337.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_3033132_10	1043205.AFYF01000001_gene55	9.759e-11	68.0	2E9QX@1|root,333X7@2|Bacteria,2GUIN@201174|Actinobacteria,4FI7J@85021|Intrasporangiaceae	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_3033132_11	196162.Noca_3456	2.15e-07	60.0	2B5NS@1|root,31YI5@2|Bacteria,2H0U0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3033132_12	1075090.GOAMR_40_00190	0.0006373	44.0	2B5NS@1|root,31YI5@2|Bacteria,2H0U0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3033132_2	469383.Cwoe_3030	1.374e-125	417.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CQYG@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158390_k127_3033132_6	882082.SaccyDRAFT_0612	9.627e-78	273.0	COG1975@1|root,COG1975@2|Bacteria,2IA9U@201174|Actinobacteria,4DXW1@85010|Pseudonocardiales	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158390_k127_3033132_1	882083.SacmaDRAFT_0810	0.0	1102.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1RG@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, large subunit	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_3034518_3	525904.Tter_0326	5.841e-08	56.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158390_k127_3034518_0	1122138.AQUZ01000090_gene3428	6.17e-155	530.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2ICMZ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158390_k127_3034518_2	247156.NFA_28310	1.804e-87	298.0	COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria,4FV5C@85025|Nocardiaceae	201174|Actinobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3034518_1	1089552.KI911559_gene1911	1.952e-100	331.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JZPA@204441|Rhodospirillales	204441|Rhodospirillales	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
SRR25158390_k127_307142_0	1229780.BN381_80375	4.27e-155	504.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,3UW9N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Anthranilate synthase component 1	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158390_k127_307142_8	1313172.YM304_22700	6.352e-36	140.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CN95@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158390_k127_307142_6	1003195.SCAT_1931	6.967e-41	155.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158390_k127_307142_2	477974.Daud_1622	1.374e-109	360.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,260VM@186807|Peptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
SRR25158390_k127_307142_4	292564.Cyagr_0757	2.04e-67	241.0	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,22SDE@167375|Cyanobium	1117|Cyanobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158390_k127_307142_5	1229780.BN381_80369	5.859e-65	231.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,3UWJ0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158390_k127_307142_7	1229172.JQFA01000004_gene1627	8.091e-37	157.0	COG4447@1|root,COG4447@2|Bacteria,1GAGV@1117|Cyanobacteria,1HF4J@1150|Oscillatoriales	1117|Cyanobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158390_k127_307142_3	1229780.BN381_80368	1.259e-83	292.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,3UWJP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158390_k127_307142_1	1313172.YM304_22610	1.785e-134	441.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CMYU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_307142_9	1229780.BN381_80362	3.826e-31	124.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,3UWFF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158390_k127_3123125_6	1449044.JMLE01000007_gene1265	2.827e-39	156.0	COG0500@1|root,COG0500@2|Bacteria,2GMRI@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_3123125_2	1137271.AZUM01000002_gene2359	2.692e-87	324.0	COG0500@1|root,COG2226@2|Bacteria,2GKH6@201174|Actinobacteria,4E2NP@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_3123125_3	1464048.JNZS01000010_gene5159	6.018e-87	313.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_3123125_7	981369.JQMJ01000004_gene2820	5.361e-27	126.0	2B3D9@1|root,31W22@2|Bacteria,2HXEE@201174|Actinobacteria,2NM1D@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3123125_5	35754.JNYJ01000101_gene9934	6.116e-45	179.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria,4DDTQ@85008|Micromonosporales	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
SRR25158390_k127_3123125_0	298654.FraEuI1c_3933	4.331e-158	531.0	COG4591@1|root,COG4591@2|Bacteria,2I445@201174|Actinobacteria	201174|Actinobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_3123125_1	1120949.KB903295_gene2300	5.884e-97	334.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4DAEI@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3123125_4	35754.JNYJ01000024_gene9064	7.712e-76	261.0	COG1695@1|root,COG1695@2|Bacteria,2IH28@201174|Actinobacteria,4DI31@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_3123125_8	100226.SCO3586	1.006e-17	93.0	2F3CR@1|root,33W6Q@2|Bacteria,2IBZI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3123125_11	1150399.AQYK01000002_gene2463	0.0002986	49.0	COG2764@1|root,COG2764@2|Bacteria,2I2KY@201174|Actinobacteria,4FTN3@85023|Microbacteriaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3132713_0	103733.JNYO01000008_gene5417	3.088e-193	621.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2HEQP@201174|Actinobacteria,4DYQU@85010|Pseudonocardiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158390_k127_3132713_1	37919.EP51_00195	3.26e-141	466.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria,4FYKD@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	sppF	-	1.14.13.200	ko:K14672,ko:K15972	ko01057,ko01130,map01057,map01130	M00783	R06704,R10954	RC02681	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	FAD_binding_3
SRR25158390_k127_3132713_3	1209984.BN978_07282	2.949e-64	232.0	COG1309@1|root,COG1309@2|Bacteria,2IFH9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3132713_2	1137269.AZWL01000033_gene3330	9.17e-113	372.0	COG3612@1|root,COG3612@2|Bacteria,2GN7K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3132713_5	797299.HALLA_01610	4.068e-18	95.0	COG0262@1|root,arCOG01490@2157|Archaea,2XXBJ@28890|Euryarchaeota,23VPE@183963|Halobacteria	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_3132713_4	1382304.JNIL01000001_gene1710	1.134e-23	108.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli,279EA@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158390_k127_3132713_6	1229780.BN381_410036	1.957e-17	84.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,3UWJB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158390_k127_3139412_7	1156919.QWC_31814	0.0001757	51.0	COG2197@1|root,COG2197@2|Bacteria,1PWGW@1224|Proteobacteria,2WC1D@28216|Betaproteobacteria,3T885@506|Alcaligenaceae	2|Bacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,Replicase
SRR25158390_k127_3139412_1	1229780.BN381_330111	5.325e-124	414.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_3139412_0	1229780.BN381_330110	1.679e-155	523.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158390_k127_3139412_6	500153.JOEK01000001_gene3961	1.481e-12	78.0	COG1846@1|root,COG1846@2|Bacteria,2IHYF@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_3139412_2	1380346.JNIH01000027_gene5813	2.082e-115	382.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_3139412_4	105420.BBPO01000004_gene1401	3.364e-85	291.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,2NHE9@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158390_k127_3139412_3	1313172.YM304_22760	1.964e-112	373.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria	201174|Actinobacteria	P	membrane protein terC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158390_k127_3139412_5	1246995.AFR_33180	4.611e-19	87.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4D961@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158390_k127_31540_3	1123024.AUII01000006_gene4591	5.021e-85	294.0	COG0583@1|root,COG0583@2|Bacteria,2I8WJ@201174|Actinobacteria,4E184@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_31540_1	219305.MCAG_01435	1.395e-122	410.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158390_k127_31540_0	1229780.BN381_110036	7.602e-129	432.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
SRR25158390_k127_31540_4	1227499.C493_01085	9.103e-17	85.0	COG2050@1|root,arCOG00777@2157|Archaea,2Y26I@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_31540_2	644283.Micau_5826	1.713e-103	353.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria,4D8QR@85008|Micromonosporales	201174|Actinobacteria	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158390_k127_31540_5	886293.Sinac_5036	1.93e-06	60.0	2AAEK@1|root,3169S@2|Bacteria,2J1M3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_320661_1	2074.JNYD01000036_gene5374	9.381e-130	422.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,4E123@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_320661_2	402881.Plav_3077	7.362e-98	332.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria,2U25T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_320661_3	258052.JNYV01000011_gene2690	2.03e-22	106.0	COG1309@1|root,COG1309@2|Bacteria,2GMNZ@201174|Actinobacteria,2M0AQ@2063|Kitasatospora	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_320661_0	426716.JOAJ01000002_gene2034	9.191e-197	617.0	COG1960@1|root,COG1960@2|Bacteria,2GJX5@201174|Actinobacteria,4FXG8@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE12_3	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3209748_0	675635.Psed_6486	3.774e-99	347.0	COG1196@1|root,COG1196@2|Bacteria,2GK6F@201174|Actinobacteria,4DYJA@85010|Pseudonocardiales	201174|Actinobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR25158390_k127_3209748_2	858619.CVAR_2857	1.739e-10	69.0	28Y1Z@1|root,31NDE@2|Bacteria,2HQZK@201174|Actinobacteria,22QAT@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3209748_1	644283.Micau_1083	1.633e-63	226.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4DF1S@85008|Micromonosporales	201174|Actinobacteria	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
SRR25158390_k127_3225647_4	351607.Acel_0379	7.33e-35	140.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_3225647_0	1246995.AFR_28360	1.503e-202	641.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4D966@85008|Micromonosporales	201174|Actinobacteria	C	Dehydrogenase	gabD1	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_3225647_5	298655.KI912267_gene6926	1.418e-31	143.0	COG2159@1|root,COG2159@2|Bacteria,2I9QG@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3225647_3	298654.FraEuI1c_4779	1.336e-37	147.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria	201174|Actinobacteria	I	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3225647_2	931627.MycrhDRAFT_4793	1.821e-85	301.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,2349B@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_3225647_1	1229780.BN381_40064	3.08e-114	383.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158390_k127_3253577_0	1380356.JNIK01000021_gene4515	0.0	1379.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4ERFA@85013|Frankiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158390_k127_3253577_1	1229780.BN381_10241	5.946e-144	471.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	pks16	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	6.2.1.20	ko:K00666,ko:K01909	ko00071,map00071	-	R01406	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AMP-binding_C_2
SRR25158390_k127_3264777_5	1313172.YM304_21110	1.918e-22	98.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CN2R@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158390_k127_3264777_1	1313172.YM304_21120	1.26e-128	422.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CMQ3@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158390_k127_3264777_4	1229780.BN381_80273	3.139e-36	147.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,3UWZU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158390_k127_3264777_3	1229780.BN381_80274	1.888e-46	175.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158390_k127_3264777_0	1313172.YM304_21150	1.747e-132	431.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_3264777_2	1283283.ATXA01000003_gene1715	4.971e-114	381.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,2GNP7@201174|Actinobacteria,4EUZW@85013|Frankiales	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD3	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Carboxyl_trans,MdcE
SRR25158390_k127_328828_6	644282.Deba_0224	3.458e-73	252.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158390_k127_328828_2	1120949.KB903294_gene3987	9.208e-128	428.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4D9UT@85008|Micromonosporales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158390_k127_328828_7	251221.35213751	1.53e-34	143.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158390_k127_328828_8	1410634.JHVD01000026_gene1686	7.245e-29	126.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria,4DTIP@85009|Propionibacteriales	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158390_k127_328828_1	1068978.AMETH_1987	7.378e-172	564.0	28IUR@1|root,2Z8TE@2|Bacteria,2I9P5@201174|Actinobacteria,4E2HC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_328828_4	1054860.KB913030_gene3436	4.168e-98	331.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_328828_0	1123024.AUII01000021_gene79	0.0	1184.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158390_k127_328828_3	1416752.AYME01000003_gene2554	7.793e-116	382.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4FMB4@85023|Microbacteriaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158390_k127_328828_5	1313172.YM304_20280	4.654e-85	294.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_328828_11	1158146.KB907121_gene921	7.411e-06	49.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales	135613|Chromatiales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158390_k127_3297606_10	298653.Franean1_5978	1.457e-05	51.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158390_k127_3297606_7	1229780.BN381_130059	9.783e-58	208.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,3UWRP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158390_k127_3297606_2	1313172.YM304_07240	5.227e-166	544.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CMQ0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158390_k127_3297606_4	338963.Pcar_2461	2.314e-120	394.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158390_k127_3297606_5	1229780.BN381_130064	1.084e-96	327.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,3UWKR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158390_k127_3297606_3	1229780.BN381_640016	4.053e-139	458.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	bglIM	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158390_k127_3297606_9	326298.Suden_0122	2.197e-12	78.0	2BUAB@1|root,32PJW@2|Bacteria,1Q49J@1224|Proteobacteria,42YP0@68525|delta/epsilon subdivisions,2YR52@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3297606_8	1127134.NOCYR_4774	1.63e-24	118.0	2CK3K@1|root,32SBH@2|Bacteria,2IQJH@201174|Actinobacteria,4G23H@85025|Nocardiaceae	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158390_k127_3297606_1	1150864.MILUP08_46168	1.818e-225	704.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4D97E@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158390_k127_3297606_6	656024.FsymDg_1221	3.039e-78	270.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4ESMS@85013|Frankiales	201174|Actinobacteria	J	PFAM tRNA rRNA methyltransferase, SpoU	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158390_k127_3297606_0	298654.FraEuI1c_1933	7.418e-237	746.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
SRR25158390_k127_3299107_7	1206720.BAFQ01000134_gene3327	1.091e-163	542.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4FU8Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3299107_11	1121272.KB903289_gene4225	2.556e-119	396.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria,4DJK3@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_3299107_26	1041159.AZUW01000020_gene1344	3.124e-69	240.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,4BD94@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
SRR25158390_k127_3299107_30	649831.L083_7352	1.181e-45	176.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DBSK@85008|Micromonosporales	2|Bacteria	K	Belongs to the sigma-70 factor family	sigB	GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_3299107_43	397278.JOJN01000001_gene2998	7.603e-12	71.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,4DSGA@85009|Propionibacteriales	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158390_k127_3299107_47	909613.UO65_3692	2.936e-10	66.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158390_k127_3299107_34	266117.Rxyl_2934	9.748e-34	139.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158390_k127_3299107_36	298655.KI912266_gene3005	2.608e-26	119.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158390_k127_3299107_27	1118060.CAGZ01000024_gene673	1.015e-59	216.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_3299107_38	1313172.YM304_34610	3.018e-24	102.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158390_k127_3299107_1	1121472.AQWN01000011_gene1225	1.227e-265	853.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
SRR25158390_k127_3299107_31	1449355.JQNR01000003_gene952	8.97e-44	165.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria	201174|Actinobacteria	K	asnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_3299107_9	316274.Haur_2764	2.991e-126	415.0	COG3185@1|root,COG3185@2|Bacteria,2G7XQ@200795|Chloroflexi,3765R@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158390_k127_3299107_48	913325.N799_00680	1.958e-09	68.0	COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3299107_28	298654.FraEuI1c_5306	1.431e-57	217.0	COG4759@1|root,COG4759@2|Bacteria	2|Bacteria	O	protein conserved in bacteria containing thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158390_k127_3299107_19	1386089.N865_02865	4.016e-87	321.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4FIXV@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
SRR25158390_k127_3299107_35	1206730.BAGA01000130_gene4388	1.338e-33	144.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,4FX60@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3299107_39	875328.JDM601_3485	3.309e-23	115.0	COG1960@1|root,COG1960@2|Bacteria,2GMTN@201174|Actinobacteria,2340Z@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158390_k127_3299107_10	471852.Tcur_0579	4.738e-123	426.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4EHHW@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_3299107_16	223184.AS25_07210	5.989e-101	336.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,1W7R4@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_3299107_22	479435.Kfla_6887	7.744e-78	276.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DNEM@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_3299107_3	1313172.YM304_38110	4.015e-209	677.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4CMPU@84992|Acidimicrobiia	201174|Actinobacteria	CP	protein synonym multiple resistance and pH homeostasis protein A	-	-	1.6.5.3	ko:K00341,ko:K05565,ko:K14086	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	DUF4040,MnhB,NADHdh,Proton_antipo_M,Proton_antipo_N
SRR25158390_k127_3299107_32	1313172.YM304_38100	3.698e-40	167.0	COG2111@1|root,COG2111@2|Bacteria,2IPGH@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Domain related to MnhB subunit of Na H antiporter	-	-	-	ko:K05565,ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
SRR25158390_k127_3299107_33	1313172.YM304_38090	5.273e-36	151.0	COG1006@1|root,COG1006@2|Bacteria,2ISBC@201174|Actinobacteria	201174|Actinobacteria	P	Multisubunit Na H antiporter MnhC subunit	mrpC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
SRR25158390_k127_3299107_6	1229780.BN381_150134	2.935e-184	598.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,3UX2B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CP	Proton-conducting membrane transporter	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158390_k127_3299107_40	1304876.AZVC01000007_gene103	8.799e-23	107.0	COG1863@1|root,COG1863@2|Bacteria,2IQD6@201174|Actinobacteria,1W96R@1268|Micrococcaceae	201174|Actinobacteria	P	Na+/H+ ion antiporter subunit	mrpE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
SRR25158390_k127_3299107_44	1229780.BN381_150136	9.018e-12	71.0	COG2212@1|root,COG2212@2|Bacteria	2|Bacteria	P	antiporter activity	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
SRR25158390_k127_3299107_42	1178537.BA1_07187	1.874e-16	89.0	COG1320@1|root,COG1320@2|Bacteria,1VABT@1239|Firmicutes,4HKX5@91061|Bacilli,1ZHVK@1386|Bacillus	91061|Bacilli	P	COG1320 Multisubunit Na H antiporter, MnhG subunit	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	iYO844.BSU31660	PhaG_MnhG_YufB
SRR25158390_k127_3299107_25	68260.JOAY01000017_gene3521	7.994e-73	253.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158390_k127_3299107_20	1068980.ARVW01000001_gene6015	9.381e-87	292.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria,4E141@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158390_k127_3299107_45	1313172.YM304_41550	7.786e-11	71.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4CN0Y@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_3299107_18	1380356.JNIK01000004_gene50	8.825e-90	310.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4ERPU@85013|Frankiales	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158390_k127_3299107_41	1266925.JHVX01000003_gene548	1.734e-16	90.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSS8@28216|Betaproteobacteria,373EX@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM Blue (type 1) copper domain	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158390_k127_3299107_23	1394178.AWOO02000026_gene5105	5.044e-74	272.0	COG0477@1|root,COG0477@2|Bacteria,2I607@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3
SRR25158390_k127_3299107_37	471857.Svir_12580	4.35e-26	124.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4DXS5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised protein, DegV family COG1307	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158390_k127_3299107_46	479434.Sthe_3108	9.08e-11	73.0	COG0344@1|root,COG0344@2|Bacteria,2GBUF@200795|Chloroflexi,27ZAT@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158390_k127_3299107_0	1120950.KB892759_gene6276	5.66e-288	913.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4DPTB@85009|Propionibacteriales	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158390_k127_3299107_21	298654.FraEuI1c_3332	8.059e-80	289.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4EV2V@85013|Frankiales	201174|Actinobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_3299107_4	298655.KI912266_gene4193	1.431e-196	633.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158390_k127_3299107_24	710687.KI912270_gene2052	5.57e-74	271.0	COG2321@1|root,COG2321@2|Bacteria,2HBKZ@201174|Actinobacteria,235R2@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zn_peptidase
SRR25158390_k127_3299107_5	1229780.BN381_330074	8.533e-193	640.0	COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,3UX4U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_3299107_14	1068978.AMETH_0145	2.031e-107	355.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DY02@85010|Pseudonocardiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3299107_12	1068978.AMETH_0144	1.246e-115	391.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E1TV@85010|Pseudonocardiales	201174|Actinobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_3299107_2	408672.NBCG_01838	3.931e-248	794.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DPKK@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_3299107_15	408672.NBCG_01837	9.378e-103	344.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DPF0@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3299107_13	882083.SacmaDRAFT_5690	5.489e-111	380.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DYYG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3299107_8	1068978.AMETH_0140	2.311e-130	429.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4E14S@85010|Pseudonocardiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_3299107_17	1229780.BN381_80379	1.239e-100	333.0	COG1960@1|root,COG1960@2|Bacteria,2GJ7S@201174|Actinobacteria,3UX8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3301799_16	58123.JOFJ01000018_gene4320	1.022e-54	204.0	COG3327@1|root,COG3327@2|Bacteria,2I1UI@201174|Actinobacteria,4EPT7@85012|Streptosporangiales	201174|Actinobacteria	K	PaaX-like protein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3301799_3	1117379.BABA_14322	7.236e-176	565.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3301799_0	649831.L083_2761	7.389e-240	754.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158390_k127_3301799_5	369723.Strop_1560	1.941e-158	522.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DAN2@85008|Micromonosporales	201174|Actinobacteria	G	Beta-glucosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158390_k127_3301799_10	408672.NBCG_01460	1.07e-104	354.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4DPNK@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158390_k127_3301799_13	118168.MC7420_8037	7.432e-93	319.0	COG1175@1|root,COG1175@2|Bacteria,1G3BG@1117|Cyanobacteria,1H8SB@1150|Oscillatoriales	1117|Cyanobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158390_k127_3301799_11	889378.Spiaf_2496	4.502e-99	338.0	COG1653@1|root,COG1653@2|Bacteria,2J6W1@203691|Spirochaetes	203691|Spirochaetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158390_k127_3301799_4	469383.Cwoe_2935	3.83e-160	514.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158390_k127_3301799_14	1463909.KL585977_gene155	4.594e-91	313.0	COG1609@1|root,COG1609@2|Bacteria,2ICJM@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_3301799_1	1229780.BN381_10220	1.529e-225	713.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,3UX9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158390_k127_3301799_9	1385518.N798_09925	9.903e-106	351.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4FE30@85021|Intrasporangiaceae	201174|Actinobacteria	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158390_k127_3301799_7	446462.Amir_2635	5.356e-115	384.0	COG0604@1|root,COG0604@2|Bacteria,2ID9Y@201174|Actinobacteria,4EBBE@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_3301799_8	83332.Rv2284	7.306e-115	385.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,232VN@1762|Mycobacteriaceae	201174|Actinobacteria	I	esterase	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158390_k127_3301799_15	1048339.KB913029_gene541	1.232e-56	205.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria,4ESUT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158390_k127_3301799_18	1110502.TMO_2442	1.614e-10	70.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,2JTAK@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_3301799_20	1121877.JQKF01000022_gene2279	3.102e-07	57.0	2A7D0@1|root,30WA0@2|Bacteria,2HH43@201174|Actinobacteria,4CP42@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_3301799_2	1229780.BN381_10212	2.418e-180	596.0	COG2304@1|root,COG2304@2|Bacteria,2HQ9B@201174|Actinobacteria,3UXG6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
SRR25158390_k127_3301799_6	882082.SaccyDRAFT_2068	1.896e-122	414.0	COG1012@1|root,COG1012@2|Bacteria,2H5M9@201174|Actinobacteria,4DY5D@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79	ko:K00135,ko:K00146	ko00250,ko00310,ko00350,ko00360,ko00643,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00360,map00643,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401,R02536	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_3301799_17	591158.SSMG_07583	2.809e-18	87.0	COG2227@1|root,COG2227@2|Bacteria,2GTJX@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158390_k127_3301799_12	1268303.RHODMAR_1295	3.05e-98	335.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4FW65@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158390_k127_3301799_22	446465.Bfae_29440	9.516e-05	52.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4FDQ9@85020|Dermabacteraceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_3310620_7	1229780.BN381_160005	2.38e-46	187.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,3UWSV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158390_k127_3310620_0	1313172.YM304_04090	1.78e-215	682.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CMP9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158390_k127_3310620_6	1313172.YM304_04080	5.079e-54	197.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CN4G@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158390_k127_3310620_4	1229780.BN381_450005	2.542e-84	291.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,3UWJQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158390_k127_3310620_8	1313172.YM304_04060	4.016e-39	153.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CN51@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158390_k127_3310620_9	1313172.YM304_04050	2.593e-31	134.0	2FE68@1|root,34663@2|Bacteria,2H83B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3310620_5	1229780.BN381_450008	1.5e-76	274.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158390_k127_3310620_3	1229780.BN381_450009	1.505e-96	325.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158390_k127_3310620_2	1229780.BN381_450010	1.169e-97	326.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158390_k127_3310620_1	1229780.BN381_450011	1.421e-100	328.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158390_k127_3343735_1	196162.Noca_0941	2.452e-202	644.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4DPZ9@85009|Propionibacteriales	201174|Actinobacteria	I	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
SRR25158390_k127_3343735_5	234621.RER_56320	3.185e-57	205.0	COG1545@1|root,COG1545@2|Bacteria,2IFQP@201174|Actinobacteria,4G0JI@85025|Nocardiaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_3343735_7	479434.Sthe_1384	1.499e-44	173.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia	189775|Thermomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158390_k127_3343735_0	1229780.BN381_130116	9.623e-285	897.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,3UX5K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158390_k127_3343735_3	105559.Nwat_1530	1.162e-97	329.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria,1X06N@135613|Chromatiales	135613|Chromatiales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158390_k127_3343735_4	358823.DF19_02895	5.383e-64	231.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria	201174|Actinobacteria	J	Flavin-nucleotide-binding protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158390_k127_3343735_6	1229780.BN381_80365	5.572e-47	184.0	28I5U@1|root,2Z890@2|Bacteria,2GKEB@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1996
SRR25158390_k127_3343735_2	1229780.BN381_80366	6.836e-141	465.0	COG4677@1|root,COG4677@2|Bacteria,2I7VB@201174|Actinobacteria	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158390_k127_3343735_8	1313172.YM304_16250	1.097e-20	97.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
SRR25158390_k127_3345677_1	1313172.YM304_16060	1.539e-98	334.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CN39@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158390_k127_3345677_2	1229780.BN381_330076	6.07e-98	337.0	COG1073@1|root,COG1073@2|Bacteria,2IB59@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_3345677_3	1313172.YM304_16070	5.485e-27	115.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CNBM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158390_k127_3345677_0	1313172.YM304_16080	5.027e-237	745.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CMSF@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,S1
SRR25158390_k127_335685_4	100226.SCO3461	1.041e-18	96.0	2FA7T@1|root,342GG@2|Bacteria,2IMMX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MauE
SRR25158390_k127_335685_3	1121378.KB899755_gene3578	3.662e-24	107.0	COG3118@1|root,COG3118@2|Bacteria,1WK9V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_335685_0	1299327.I546_5694	2.848e-138	445.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,234XD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_335685_1	557599.MKAN_13550	1.334e-50	193.0	COG0664@1|root,COG0664@2|Bacteria,2IB1J@201174|Actinobacteria,237EQ@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21884	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_335685_2	1246995.AFR_23035	3.384e-29	120.0	2DW5E@1|root,33YM7@2|Bacteria,2GSAI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_342796_26	1313172.YM304_28640	0.0002199	52.0	2968S@1|root,2ZTIT@2|Bacteria,2HEBZ@201174|Actinobacteria,4CNCH@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_342796_8	1229780.BN381_10181	1.58e-139	470.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcaI	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
SRR25158390_k127_342796_12	365528.KB891219_gene1134	3.875e-123	405.0	COG0438@1|root,COG0438@2|Bacteria,2IJX1@201174|Actinobacteria,4EV7B@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_342796_15	351607.Acel_0448	3.083e-91	316.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4EU38@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_342796_10	1229780.BN381_10178	1.934e-127	418.0	COG0451@1|root,COG0451@2|Bacteria,2GP0W@201174|Actinobacteria,3UX7T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	RmlD substrate binding domain	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158390_k127_342796_13	1206732.BAGD01000075_gene3047	4.941e-93	318.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4G84K@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158390_k127_342796_7	926550.CLDAP_15490	2.148e-141	462.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_342796_3	1229780.BN381_10176	2.149e-160	516.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,3UW6R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158390_k127_342796_20	1054860.KB913030_gene4080	3.984e-72	252.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
SRR25158390_k127_342796_19	1122939.ATUD01000001_gene433	8.241e-76	279.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4CTED@84995|Rubrobacteria	84995|Rubrobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158390_k127_342796_6	443255.SCLAV_3761	2.198e-144	486.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.98.3	ko:K16653	-	-	-	-	ko00000,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158390_k127_342796_16	1229780.BN381_10136	4.263e-89	302.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,3UWQ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158390_k127_342796_9	1229780.BN381_10113	7.88e-137	441.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,3UWG6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	strE	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_342796_17	1229780.BN381_10112	1.429e-82	280.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	1.1.1.133,4.2.1.46,5.1.3.13	ko:K00067,ko:K01710,ko:K01790	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R02777,R06513,R06514	RC00182,RC00402,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158390_k127_342796_4	1229780.BN381_10111	1.25e-153	497.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,3UWQW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158390_k127_342796_21	1229780.BN381_310079	6.285e-64	241.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,3UXS8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158390_k127_342796_5	1120950.KB892785_gene223	6.416e-147	482.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DNK5@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_342796_11	1116232.AHBF01000014_gene3021	2.949e-125	422.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria	201174|Actinobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158390_k127_342796_14	1449355.JQNR01000005_gene5216	1.208e-91	309.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158390_k127_342796_23	867903.ThesuDRAFT_01585	2.201e-41	168.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WCNE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158390_k127_342796_0	1229780.BN381_10171	3.075e-262	819.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,3UWDD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158390_k127_342796_24	469383.Cwoe_1506	6.098e-14	83.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158390_k127_342796_2	1313172.YM304_28810	1.875e-197	624.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CMT7@84992|Acidimicrobiia	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_342796_18	216594.MMAR_4973	1.268e-78	271.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,235M0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Permease component	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158390_k127_342796_22	525368.HMPREF0591_2394	3.765e-62	222.0	COG1117@1|root,COG1117@2|Bacteria,2ID49@201174|Actinobacteria,2384V@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	pstB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158390_k127_342796_1	1244869.H261_08693	2.101e-218	686.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158390_k127_3432906_7	330779.Saci_0070	9.727e-07	54.0	COG4353@1|root,arCOG01699@2157|Archaea,2XR1F@28889|Crenarchaeota	28889|Crenarchaeota	S	uncharacterised conserved protein UCP017998	-	-	-	-	-	-	-	-	-	-	-	-	DUF1122
SRR25158390_k127_3432906_1	1146883.BLASA_1744	9.511e-90	306.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4ETZ3@85013|Frankiales	201174|Actinobacteria	L	Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158390_k127_3432906_3	1120950.KB892720_gene1810	2.286e-66	239.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4DR4F@85009|Propionibacteriales	201174|Actinobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158390_k127_3432906_6	446468.Ndas_0019	1.162e-43	178.0	2DW65@1|root,32V0W@2|Bacteria,2I85F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3432906_2	931277.C448_11261	1.93e-71	255.0	COG1812@1|root,arCOG01678@2157|Archaea,2XT7J@28890|Euryarchaeota,23SYQ@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the formation of S-adenosylmethionine from methionine and ATP	mat	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
SRR25158390_k127_3432906_4	1229780.BN381_60027	1.665e-62	220.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,3UWWF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158390_k127_3432906_0	1120956.JHZK01000014_gene1730	1.422e-115	398.0	COG1488@1|root,COG1488@2|Bacteria,1Q5Q0@1224|Proteobacteria,2VC10@28211|Alphaproteobacteria,1JNCQ@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	-	-	-	-	-	-	-	-	-	-	NAPRTase
SRR25158390_k127_3432906_5	426117.M446_2773	4.31e-51	190.0	COG2242@1|root,COG2242@2|Bacteria,1R06P@1224|Proteobacteria,2TYKJ@28211|Alphaproteobacteria,1JWK2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158390_k127_3438647_19	1123237.Salmuc_00511	2.838e-24	104.0	COG1793@1|root,COG1793@2|Bacteria,1NTIR@1224|Proteobacteria,2UPWW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_3438647_9	1313172.YM304_15550	6.972e-117	392.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4CMRY@84992|Acidimicrobiia	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3438647_18	1121877.JQKF01000010_gene689	1.706e-36	148.0	COG0704@1|root,COG0704@2|Bacteria,2HGEH@201174|Actinobacteria,4CNCK@84992|Acidimicrobiia	84992|Acidimicrobiia	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158390_k127_3438647_0	1229780.BN381_80236	1.079e-221	705.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,3UXSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3438647_3	1229780.BN381_80237	4.115e-172	547.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3438647_12	929712.KI912613_gene27	1.313e-101	353.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4CSB4@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158390_k127_3438647_20	298655.KI912266_gene1059	8.698e-24	107.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4ET3M@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_3438647_4	570268.ANBB01000002_gene218	2.518e-149	480.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4EGFJ@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3438647_6	1229780.BN381_10277	1.458e-138	448.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,3UXGG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158390_k127_3438647_7	1229780.BN381_10278	1.511e-127	420.0	COG0644@1|root,COG0644@2|Bacteria,2HG44@201174|Actinobacteria,3UXPV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_3438647_15	1229780.BN381_10280	8.831e-83	301.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,3UXFH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158390_k127_3438647_8	1229780.BN381_250119	1.294e-122	410.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158390_k127_3438647_10	1280946.HY29_07300	2.363e-111	366.0	COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,2U8BE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158390_k127_3438647_13	1463855.JOHV01000024_gene4546	2.362e-95	316.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158390_k127_3438647_2	1313172.YM304_27360	1.412e-199	643.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158390_k127_3438647_21	1169161.KB897726_gene1540	3.024e-15	84.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria	201174|Actinobacteria	L	methylated DNA-protein cysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR25158390_k127_3438647_17	502025.Hoch_5381	1.731e-61	222.0	COG4221@1|root,COG4221@2|Bacteria,1QVTE@1224|Proteobacteria	1224|Proteobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	yueD	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3438647_11	402881.Plav_2677	8.811e-103	349.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2U0EC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158390_k127_3438647_14	350058.Mvan_4421	4.984e-85	289.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,233VA@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM inositol monophosphatase	cysQ_1	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158390_k127_3438647_5	685727.REQ_17320	2.604e-149	484.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4FUKW@85025|Nocardiaceae	201174|Actinobacteria	EH	sulfate adenylyltransferase	cysD	GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158390_k127_3438647_1	479432.Sros_8600	7.341e-212	666.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4EFW9@85012|Streptosporangiales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158390_k127_3438647_16	247156.NFA_24540	4.084e-67	240.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4FUHJ@85025|Nocardiaceae	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158390_k127_3439092_2	65093.PCC7418_1893	5.617e-53	186.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria	1117|Cyanobacteria	JM	Glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR25158390_k127_3439092_0	1380347.JNII01000006_gene1097	1.071e-127	433.0	COG1132@1|root,COG1132@2|Bacteria,2HXAQ@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_3439092_1	1123320.KB889607_gene9519	2.411e-73	265.0	COG0438@1|root,COG0438@2|Bacteria,2I6NY@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_3439092_3	1229780.BN381_300015	0.0005502	47.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,2GKCA@201174|Actinobacteria,3UX7D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158390_k127_3447046_4	493475.GARC_4235	6.671e-121	423.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158390_k127_3447046_0	1229780.BN381_90023	0.0	1449.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,3UX1U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
SRR25158390_k127_3447046_2	1120949.KB903350_gene8127	3.481e-174	559.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DGWD@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158390_k127_3447046_7	1246448.ANAZ01000003_gene5429	8.626e-54	197.0	COG1802@1|root,COG1802@2|Bacteria,2GMZ9@201174|Actinobacteria,4EIWE@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_3447046_1	561175.KB894101_gene4649	2.172e-179	573.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4EN0I@85012|Streptosporangiales	201174|Actinobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_3447046_3	1394178.AWOO02000064_gene67	5.651e-154	497.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4EMS2@85012|Streptosporangiales	201174|Actinobacteria	E	Aminotransferase class-III	gabT2	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_3447046_6	1236902.ANAS01000005_gene4917	1.652e-58	210.0	COG2164@1|root,COG2164@2|Bacteria,2I8JP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
SRR25158390_k127_3447046_8	1043205.AFYF01000004_gene1351	4.265e-53	206.0	COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria	201174|Actinobacteria	Q	Catalyzes the conversion of maleate to fumarate	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158390_k127_3447046_10	762963.HMPREF9056_00744	3.682e-11	73.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D52E@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158390_k127_3447046_5	561175.KB894101_gene4653	1.009e-78	270.0	COG3473@1|root,COG3473@2|Bacteria,2GKP7@201174|Actinobacteria,4EMAU@85012|Streptosporangiales	201174|Actinobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158390_k127_3456973_7	1229780.BN381_80295	7.582e-95	314.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158390_k127_3456973_15	1333998.M2A_0370	2.639e-67	236.0	COG1011@1|root,COG1011@2|Bacteria,1Q69X@1224|Proteobacteria,2TTTP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolase	MA20_23095	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158390_k127_3456973_3	1123024.AUII01000021_gene69	9.687e-167	561.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158390_k127_3456973_10	1313172.YM304_23320	4.234e-85	302.0	COG0539@1|root,COG0539@2|Bacteria,2I7V9@201174|Actinobacteria	201174|Actinobacteria	J	Zc3h12a-like Ribonuclease NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	HC2,RNase_Zc3h12a
SRR25158390_k127_3456973_8	1313172.YM304_23330	3.311e-91	306.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CN0I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158390_k127_3456973_18	1229780.BN381_10319	3.483e-45	178.0	COG2050@1|root,COG2050@2|Bacteria,2I11Y@201174|Actinobacteria,3UXR4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_3456973_4	222534.KB893728_gene5546	6.56e-158	504.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EU12@85013|Frankiales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_3456973_28	1125863.JAFN01000001_gene804	0.0001681	52.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,42P4U@68525|delta/epsilon subdivisions,2WKXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_3456973_5	1229780.BN381_10320	1.659e-142	490.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,3UW87@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158390_k127_3456973_21	266940.Krad_4165	4.93e-38	153.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158390_k127_3456973_17	1229780.BN381_10321	1.016e-48	188.0	COG3428@1|root,COG3428@2|Bacteria,2I7V5@201174|Actinobacteria,3UX0M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158390_k127_3456973_16	1313172.YM304_23360	1.006e-55	207.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
SRR25158390_k127_3456973_13	1229780.BN381_10324	6.656e-81	284.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,3UWRM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158390_k127_3456973_9	1313172.YM304_17870	5.683e-91	310.0	COG1085@1|root,COG1085@2|Bacteria,2IJIM@201174|Actinobacteria	201174|Actinobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158390_k127_3456973_11	1211815.CBYP010000073_gene3644	5.288e-85	297.0	COG0025@1|root,COG0025@2|Bacteria,2GKCK@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_3456973_14	2045.KR76_27150	4.617e-77	284.0	COG2021@1|root,COG2021@2|Bacteria,2I3NA@201174|Actinobacteria,4DWXD@85009|Propionibacteriales	201174|Actinobacteria	E	Serine aminopeptidase, S33	lipG2	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_3456973_2	1229780.BN381_10333	1.636e-185	599.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,3UWNW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158390_k127_3456973_12	1125971.ASJB01000065_gene6207	9.64e-83	285.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DZX7@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158390_k127_3456973_20	585531.HMPREF0063_11964	4.195e-40	153.0	COG2329@1|root,COG2329@2|Bacteria,2IM1Q@201174|Actinobacteria,4DRA4@85009|Propionibacteriales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
SRR25158390_k127_3456973_22	1229780.BN381_10335	7.258e-30	125.0	291CY@1|root,2ZNZT@2|Bacteria,2HDEE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3456973_23	351607.Acel_1585	2.465e-29	123.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4ET4W@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_3456973_19	67373.JOBF01000005_gene2126	1.226e-43	164.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_3456973_0	1229780.BN381_10340	5.712e-311	960.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,3UWAV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158390_k127_3456973_26	1313172.YM304_18490	3.011e-22	106.0	COG1278@1|root,COG1278@2|Bacteria,2HC2C@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	-
SRR25158390_k127_3456973_25	479433.Caci_8027	1.66e-25	108.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158390_k127_3456973_6	1121877.JQKF01000004_gene1079	2.56e-107	369.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CMTA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158390_k127_3456973_1	1313172.YM304_18530	7.837e-267	844.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CMPC@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158390_k127_3456973_29	1160137.KB907310_gene4747	0.0007214	50.0	COG0748@1|root,COG0748@2|Bacteria,2I2RZ@201174|Actinobacteria,4G9GC@85025|Nocardiaceae	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_3458806_5	1229780.BN381_100028	1.364e-09	62.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158390_k127_3458806_1	402881.Plav_0570	2.394e-173	564.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2U3CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3458806_6	767817.Desgi_3254	0.0001245	54.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
SRR25158390_k127_3458806_0	402881.Plav_2680	1.059e-194	623.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158390_k127_3458806_2	882083.SacmaDRAFT_5546	1.049e-136	450.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4E0C4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_3458806_3	1122622.ATWJ01000013_gene79	2.466e-31	125.0	2DJKR@1|root,32YT5@2|Bacteria,2I86F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3458806_4	37919.EP51_33505	9.893e-16	78.0	COG0300@1|root,COG0300@2|Bacteria,2I9IM@201174|Actinobacteria,4FY3P@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,adh_short
SRR25158390_k127_3473712_19	1380393.JHVP01000008_gene4508	3.823e-37	145.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria	201174|Actinobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide,Pentapeptide_4
SRR25158390_k127_3473712_12	1121380.JNIW01000022_gene225	5.909e-100	340.0	COG3177@1|root,COG3177@2|Bacteria,1WK41@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
SRR25158390_k127_3473712_6	471852.Tcur_3987	1.42e-123	431.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria,4EGS6@85012|Streptosporangiales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158390_k127_3473712_2	1449976.KALB_3405	2.07e-198	632.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,4E0V7@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3473712_16	33898.JRHJ01000016_gene4026	2.1e-54	196.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_3473712_18	298655.KI912266_gene5567	2.077e-44	169.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_3473712_9	68223.JNZY01000010_gene1604	2.215e-118	402.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158390_k127_3473712_3	298655.KI912266_gene5569	1.113e-180	576.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158390_k127_3473712_11	298654.FraEuI1c_1368	9.328e-106	358.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_3473712_7	298654.FraEuI1c_5098	8.108e-121	413.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_3473712_15	35754.JNYJ01000002_gene6756	5.31e-62	236.0	COG2271@1|root,COG2271@2|Bacteria,2I3JQ@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
SRR25158390_k127_3473712_10	1122614.JHZF01000011_gene869	7.328e-110	372.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2PF1U@252301|Oceanicola	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3473712_14	1229780.BN381_130223	1.583e-74	259.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_3473712_1	105422.BBPM01000039_gene766	7.328e-225	707.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,2NGIS@228398|Streptacidiphilus	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3473712_17	1121272.KB903292_gene3948	4.246e-54	207.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_3473712_4	1121272.KB903292_gene3947	7.296e-152	502.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4DJIF@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3473712_13	1121272.KB903292_gene3945	9.218e-75	261.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D8XW@85008|Micromonosporales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_3473712_20	1229780.BN381_130218	3.263e-16	85.0	2FIRN@1|root,34AHB@2|Bacteria,2IHJ0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3473712_21	1206744.BAGL01000125_gene6389	3.562e-06	60.0	2FB55@1|root,343BG@2|Bacteria,2IKSK@201174|Actinobacteria,4G1P9@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3473712_8	1313172.YM304_30920	1.061e-119	414.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3473712_5	1229780.BN381_130222	1.604e-129	440.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_3473712_0	1229780.BN381_130221	2.299e-226	706.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3478297_7	298653.Franean1_2999	1.281e-39	161.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_3478297_1	269800.Tfu_2505	3.765e-246	768.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4EIAX@85012|Streptosporangiales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158390_k127_3478297_0	469383.Cwoe_2565	1.043e-278	899.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CR1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158390_k127_3478297_5	1229780.BN381_10202	4.657e-98	331.0	COG2222@1|root,COG2222@2|Bacteria,2HGM1@201174|Actinobacteria,3UXD9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS,bact-PGI_C
SRR25158390_k127_3478297_9	1229780.BN381_10201	3.4e-28	116.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158390_k127_3478297_4	1121877.JQKF01000008_gene665	5.29e-169	543.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158390_k127_3478297_6	1229780.BN381_130002	2.142e-77	295.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_3478297_3	1229780.BN381_10199	2.642e-208	685.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3478297_8	1313172.YM304_28510	3.154e-29	126.0	COG1266@1|root,COG1266@2|Bacteria,2H0BD@201174|Actinobacteria,4CNBE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158390_k127_3478297_10	596328.HMPREF0578_2008	1.144e-13	78.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,4D62M@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
SRR25158390_k127_3478297_2	1313172.YM304_28530	5.069e-235	746.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158390_k127_3478297_11	1313172.YM304_28540	8.455e-07	51.0	COG0526@1|root,COG0526@2|Bacteria,2H7FG@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3483632_0	1382356.JQMP01000003_gene1321	0.0	1294.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,27Z18@189775|Thermomicrobia	189775|Thermomicrobia	E	GXGXG motif	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158390_k127_3483632_10	47839.CCAU010000017_gene4104	1.338e-33	151.0	COG0515@1|root,COG3055@1|root,COG0515@2|Bacteria,COG3055@2|Bacteria,2I4I0@201174|Actinobacteria,23F8F@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	PFAM Protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Pkinase
SRR25158390_k127_3483632_1	1380394.JADL01000005_gene5669	9.378e-227	712.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,2JWSX@204441|Rhodospirillales	204441|Rhodospirillales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_3483632_6	1313172.YM304_24400	2.781e-83	282.0	COG2188@1|root,COG2188@2|Bacteria,2HF8W@201174|Actinobacteria,4CN6C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158390_k127_3483632_12	1041159.AZUW01000029_gene709	7.735e-31	139.0	COG0346@1|root,COG0346@2|Bacteria,1N15G@1224|Proteobacteria,2UCYE@28211|Alphaproteobacteria,4BEKA@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3483632_11	1283299.AUKG01000002_gene3725	5.802e-32	143.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRI8@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_3,GGDEF
SRR25158390_k127_3483632_7	1313172.YM304_21260	1.833e-72	255.0	COG0583@1|root,COG0583@2|Bacteria,2HF8Y@201174|Actinobacteria,4CN2C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_3483632_2	1229780.BN381_430036	5.132e-206	676.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,3UW6Y@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_3483632_4	469383.Cwoe_0785	2.181e-107	356.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158390_k127_3483632_5	211165.AJLN01000137_gene1503	1.951e-90	316.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1JI27@1189|Stigonemataceae	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3483632_8	101510.RHA1_ro01953	4.827e-52	196.0	COG3884@1|root,COG3884@2|Bacteria,2H0CD@201174|Actinobacteria,4FVXD@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
SRR25158390_k127_3483632_9	1463881.KL591015_gene591	1.799e-37	147.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_3483632_3	1313172.YM304_21200	1.171e-140	456.0	COG1960@1|root,COG1960@2|Bacteria,2GJ7S@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3483632_13	1123023.JIAI01000028_gene4524	1.057e-16	85.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DZ1D@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_3485702_3	1123237.Salmuc_00511	3.459e-73	253.0	COG1793@1|root,COG1793@2|Bacteria,1NTIR@1224|Proteobacteria,2UPWW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_3485702_2	1123237.Salmuc_00513	1.643e-78	282.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2U655@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158390_k127_3485702_9	1032480.MLP_24830	8.615e-32	130.0	COG1595@1|root,COG1595@2|Bacteria,2HG34@201174|Actinobacteria,4DWA5@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3485702_7	644283.Micau_3569	1.281e-48	181.0	COG1309@1|root,COG1309@2|Bacteria,2IEU9@201174|Actinobacteria,4DCCF@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3485702_12	1463841.JOIR01000038_gene3440	2.866e-25	109.0	COG4319@1|root,COG4319@2|Bacteria,2GNV0@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158390_k127_3485702_6	298655.KI912266_gene5659	8.605e-54	200.0	COG0596@1|root,COG0596@2|Bacteria,2I51U@201174|Actinobacteria,4EXEG@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_3485702_11	1449049.JONW01000010_gene3671	1.221e-25	120.0	COG0454@1|root,COG0454@2|Bacteria,1QVFM@1224|Proteobacteria,2TWDR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158390_k127_3485702_0	1229780.BN381_80226	1.033e-89	307.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158390_k127_3485702_8	1313172.YM304_15490	1.908e-33	136.0	COG0671@1|root,COG0671@2|Bacteria,2HGAE@201174|Actinobacteria,4CN9F@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158390_k127_3485702_4	710111.FraQA3DRAFT_2748	3.957e-70	242.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158390_k127_3485702_5	43759.JNWK01000013_gene6439	5.652e-58	213.0	COG4803@1|root,COG4803@2|Bacteria,2IQV0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158390_k127_3485702_10	583355.Caka_2718	2.281e-29	128.0	COG3132@1|root,COG3132@2|Bacteria,46VIH@74201|Verrucomicrobia,3K85I@414999|Opitutae	414999|Opitutae	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SRR25158390_k127_3485702_1	1229780.BN381_80222	5.478e-79	289.0	COG0076@1|root,COG2141@1|root,COG0076@2|Bacteria,COG2141@2|Bacteria,2GK3J@201174|Actinobacteria,3UWS0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158390_k127_3510417_6	861299.J421_1532	2.991e-16	86.0	COG0021@1|root,COG0021@2|Bacteria,1ZTA2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158390_k127_3510417_1	378806.STAUR_7628	5.424e-64	228.0	COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,42W6J@68525|delta/epsilon subdivisions,2WSAJ@28221|Deltaproteobacteria,2YZEF@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_3510417_4	525909.Afer_0497	2.017e-39	166.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CNH1@84992|Acidimicrobiia	84992|Acidimicrobiia	G	ROK family	-	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158390_k127_3510417_3	446468.Ndas_0019	1.231e-45	184.0	2DW65@1|root,32V0W@2|Bacteria,2I85F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3510417_0	485913.Krac_12393	3.109e-214	696.0	COG3387@1|root,COG3387@2|Bacteria,2G7S0@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG3387 Glucoamylase and related glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158390_k127_3510417_5	1050202.KB913024_gene3613	9.369e-39	166.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,40AFT@622450|Actinopolysporales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_3510417_7	1206101.AZXC01000017_gene3652	9.791e-05	50.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,HTH_3
SRR25158390_k127_3510417_2	1906.SFRA_03245	2.408e-63	222.0	COG1595@1|root,COG1595@2|Bacteria,2GJG2@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3555915_6	1229780.BN381_80216	3.974e-48	175.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_3555915_10	882082.SaccyDRAFT_3134	8.587e-12	68.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4E75F@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158390_k127_3555915_0	1313172.YM304_15410	1.946e-193	609.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_3555915_7	1229780.BN381_80214	6.408e-36	145.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,3UXQE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158390_k127_3555915_5	1229780.BN381_80213	6.068e-101	336.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRR25158390_k127_3555915_9	1089546.AQUI01000002_gene2747	6.053e-15	81.0	COG3255@1|root,COG3255@2|Bacteria,2GS4C@201174|Actinobacteria	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158390_k127_3555915_3	1229780.BN381_80211	2.282e-106	355.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,3UWN4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158390_k127_3555915_8	1229780.BN381_410019	1.801e-22	107.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158390_k127_3555915_2	1229780.BN381_410018	1.224e-121	407.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,3UWHD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158390_k127_3555915_1	1229780.BN381_80206	1.138e-174	557.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
SRR25158390_k127_3555915_4	1229780.BN381_510003	4.062e-103	352.0	COG1824@1|root,COG1824@2|Bacteria,2H441@201174|Actinobacteria	201174|Actinobacteria	P	Integral membrane	-	-	-	-	-	-	-	-	-	-	-	-	MgtE
SRR25158390_k127_3567489_2	66875.JODY01000017_gene619	3.895e-125	402.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158390_k127_3567489_1	47763.JNZA01000043_gene6324	8.046e-139	447.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	mcl2	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI,PEP-utilizers_C
SRR25158390_k127_3567489_4	1218076.BAYB01000007_gene1323	4.243e-68	243.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2WGHU@28216|Betaproteobacteria,1K427@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3567489_3	882086.SacxiDRAFT_0956	1.741e-103	341.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4DZM2@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158390_k127_3567489_0	1229780.BN381_210057	9.669e-233	731.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3567489_7	467200.ACFA01000335_gene771	1.744e-06	60.0	2DPU0@1|root,333DA@2|Bacteria,2IARZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3567489_6	1134445.AJJM01000027_gene4435	3.083e-08	65.0	2DPU0@1|root,333DA@2|Bacteria,2GNE1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3567489_5	1313172.YM304_14250	3.712e-65	226.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CMYB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_357424_7	570268.ANBB01000046_gene1407	2.738e-06	50.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4EH5Q@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158390_k127_357424_4	1122611.KB903996_gene7563	1.714e-12	74.0	COG1366@1|root,COG1366@2|Bacteria,2IKUF@201174|Actinobacteria,4EKP8@85012|Streptosporangiales	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158390_k127_357424_2	298654.FraEuI1c_0808	6.924e-55	207.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4ES7X@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_357424_5	266117.Rxyl_2974	1.446e-09	66.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbT	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2,SpoIIE
SRR25158390_k127_357424_1	1229780.BN381_80132	1.55e-81	278.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,3UWGQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158390_k127_357424_0	1229780.BN381_80133	4.073e-229	721.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,3UW8I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158390_k127_357424_3	1313172.YM304_12870	6.287e-54	198.0	COG1414@1|root,COG1414@2|Bacteria,2HGKQ@201174|Actinobacteria,4CP2Q@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_357424_6	298655.KI912266_gene21	1.448e-06	60.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_3601590_12	1229780.BN381_250088	5.65e-57	207.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158390_k127_3601590_7	1280948.HY36_03850	2.2e-104	356.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,43Z46@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3601590_14	1229780.BN381_130223	1.059e-34	143.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_3601590_5	479433.Caci_5895	1.783e-131	439.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_3601590_11	1463920.JOGB01000009_gene764	2.404e-68	236.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_3601590_13	1229780.BN381_20007	2.422e-51	194.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_3601590_3	33898.JRHJ01000016_gene4025	9.205e-151	497.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158390_k127_3601590_1	981369.JQMJ01000004_gene1451	1.233e-198	626.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,2NGJB@228398|Streptacidiphilus	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	ltp3	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158390_k127_3601590_9	208439.AJAP_26860	2.208e-78	286.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DYN3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158390_k127_3601590_4	1229780.BN381_310036	8.091e-135	439.0	COG4638@1|root,COG4638@2|Bacteria,2IA3C@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158390_k127_3601590_8	390989.JOEG01000001_gene5357	2.545e-102	347.0	COG3599@1|root,COG3599@2|Bacteria,2I2UK@201174|Actinobacteria,4D9JS@85008|Micromonosporales	201174|Actinobacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158390_k127_3601590_2	1136417.AZWE01000005_gene4552	4.656e-155	496.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DBBX@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3601590_10	1487953.JMKF01000095_gene5153	2.336e-77	277.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3601590_6	2074.JNYD01000022_gene1437	4.242e-131	464.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXJW@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158390_k127_3601590_0	269800.Tfu_1398	0.0	1228.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4EI8D@85012|Streptosporangiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158390_k127_3619994_1	189753.AXAS01000001_gene3634	2.32e-98	329.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2U0D7@28211|Alphaproteobacteria,3JXW9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3619994_3	1123020.AUIE01000019_gene2872	1.178e-77	284.0	COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,1TBH0@1236|Gammaproteobacteria,1YHIP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3619994_0	1445613.JALM01000010_gene2370	7.118e-167	550.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DYDI@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_3619994_2	543632.JOJL01000061_gene2343	1.481e-82	286.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	chqB	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
SRR25158390_k127_3619994_4	1313172.YM304_11920	5.906e-66	243.0	COG0500@1|root,COG2226@2|Bacteria,2HFKS@201174|Actinobacteria,4CNX7@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3619994_6	83406.HDN1F_12000	1.998e-20	107.0	COG3255@1|root,COG3255@2|Bacteria,1N01E@1224|Proteobacteria,1SBCB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158390_k127_3619994_5	390989.JOEG01000003_gene4685	3.652e-60	216.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4DDPF@85008|Micromonosporales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3620306_1	1229780.BN381_20132	2.901e-179	579.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,3UXHK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_3620306_3	136273.GY22_11305	7.368e-28	132.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,1W98Q@1268|Micrococcaceae	201174|Actinobacteria	L	UreE urease accessory protein, C-terminal domain	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_3620306_0	1380387.JADM01000002_gene2155	4.504e-235	765.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,1XNCE@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3620306_2	929712.KI912613_gene1696	9.445e-85	291.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4CQ02@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3620306_4	1229780.BN381_80222	2.282e-24	105.0	COG0076@1|root,COG2141@1|root,COG0076@2|Bacteria,COG2141@2|Bacteria,2GK3J@201174|Actinobacteria,3UWS0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158390_k127_3648882_45	551115.Aazo_2523	1.289e-06	52.0	COG0765@1|root,COG0765@2|Bacteria,1GQ0J@1117|Cyanobacteria,1HK34@1161|Nostocales	1117|Cyanobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158390_k127_3648882_15	1313172.YM304_29130	9.864e-106	357.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SRR25158390_k127_3648882_25	471852.Tcur_3399	7.627e-59	209.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4EJJC@85012|Streptosporangiales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158390_k127_3648882_30	1247963.JPHU01000004_gene480	8.681e-42	164.0	COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,2U4CU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
SRR25158390_k127_3648882_26	33876.JNXY01000006_gene1250	3.97e-54	197.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4DBT1@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158390_k127_3648882_19	1313172.YM304_14930	2.188e-81	283.0	COG2120@1|root,COG2120@2|Bacteria,2IR6Y@201174|Actinobacteria,4CN50@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158390_k127_3648882_28	1229780.BN381_80155	3.129e-45	174.0	COG1920@1|root,COG1920@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158390_k127_3648882_12	1123024.AUII01000019_gene3982	3.124e-116	400.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4DZUJ@85010|Pseudonocardiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3648882_10	1313172.YM304_14950	2.331e-123	406.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158390_k127_3648882_9	1260251.SPISAL_08000	1.169e-127	439.0	COG3387@1|root,COG3387@2|Bacteria,1RDWY@1224|Proteobacteria,1T141@1236|Gammaproteobacteria,1X17G@135613|Chromatiales	135613|Chromatiales	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3648882_27	43354.JOIJ01000037_gene3226	3.693e-53	208.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158390_k127_3648882_4	479431.Namu_4908	1.858e-189	604.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4EUJP@85013|Frankiales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158390_k127_3648882_41	754035.Mesau_00029	2.736e-17	94.0	COG2764@1|root,COG2764@2|Bacteria,1RF2S@1224|Proteobacteria,2U9MB@28211|Alphaproteobacteria,43P6D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3648882_29	452652.KSE_42250	3.422e-44	175.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria,2M4H6@2063|Kitasatospora	201174|Actinobacteria	K	Sigma-70, region 4	sig49	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3648882_21	1246995.AFR_30425	3.531e-65	226.0	COG2318@1|root,COG2318@2|Bacteria,2IM8X@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_3648882_20	1169161.KB897725_gene1814	2.062e-71	249.0	COG2197@1|root,COG2197@2|Bacteria,2GN29@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_3648882_17	1246995.AFR_16250	3.65e-94	338.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I8X1@201174|Actinobacteria,4DH0K@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HisKA_3
SRR25158390_k127_3648882_36	469383.Cwoe_3719	3.91e-28	132.0	COG2197@1|root,COG2197@2|Bacteria,2I5RT@201174|Actinobacteria	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158390_k127_3648882_8	479432.Sros_0829	9.926e-134	462.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158390_k127_3648882_22	1254432.SCE1572_16470	1.583e-63	238.0	COG1520@1|root,COG1520@2|Bacteria,1QAB1@1224|Proteobacteria,434Y4@68525|delta/epsilon subdivisions,2X92T@28221|Deltaproteobacteria,2Z1KW@29|Myxococcales	28221|Deltaproteobacteria	G	PQQ enzyme repeat	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	PQQ,PQQ_2
SRR25158390_k127_3648882_44	1907.SGLAU_07055	6.498e-09	63.0	2DXB5@1|root,3447Q@2|Bacteria,2GW9K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3648882_43	1089544.KB912942_gene490	9.656e-11	67.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_3648882_31	1298863.AUEP01000007_gene386	2.52e-41	154.0	2C6EM@1|root,2ZFYQ@2|Bacteria,2GXX8@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRR25158390_k127_3648882_38	164757.Mjls_1687	1.821e-22	110.0	2DZHZ@1|root,31ZDG@2|Bacteria,2IN6I@201174|Actinobacteria,23A9W@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3648882_2	591157.SSLG_00197	9.258e-207	654.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158390_k127_3648882_13	1229780.BN381_10328	3.381e-114	388.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158390_k127_3648882_24	1137269.AZWL01000009_gene3754	4.277e-61	222.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
SRR25158390_k127_3648882_23	196162.Noca_4918	2.791e-63	234.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4DT1D@85009|Propionibacteriales	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
SRR25158390_k127_3648882_42	164757.Mjls_0915	4.601e-15	81.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,235GC@1762|Mycobacteriaceae	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158390_k127_3648882_40	1108045.GORHZ_085_00220	8.722e-21	100.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4GAJV@85026|Gordoniaceae	201174|Actinobacteria	K	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
SRR25158390_k127_3648882_39	1171373.PACID_26860	2.217e-21	98.0	2DPEX@1|root,331T0@2|Bacteria,2IR24@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158390_k127_3648882_34	930169.B5T_02493	1.009e-30	126.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria	1224|Proteobacteria	Q	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_3648882_6	1229780.BN381_410026	1.71e-165	533.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,3UWN8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	-	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158390_k127_3648882_0	1197130.BAFM01000017_gene2644	5.126e-245	779.0	COG3119@1|root,arCOG02791@2157|Archaea,2Y8G8@28890|Euryarchaeota,23VJY@183963|Halobacteria	183963|Halobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_3648882_14	84531.JMTZ01000031_gene111	3.524e-114	379.0	COG0500@1|root,COG2226@2|Bacteria,1PE3E@1224|Proteobacteria,1S3T0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_3648882_18	67275.JOAP01000021_gene1957	4.152e-85	294.0	2BXSN@1|root,32R1X@2|Bacteria,2GN1N@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
SRR25158390_k127_3648882_3	1155718.KB891879_gene5100	7.362e-205	664.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_3648882_7	469383.Cwoe_5782	5.012e-158	533.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I3CX@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158390_k127_3648882_37	512565.AMIS_28380	5.464e-28	121.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,4DCX9@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3648882_32	1172185.KB911511_gene3023	7.223e-36	143.0	COG3832@1|root,COG3832@2|Bacteria,2IDAT@201174|Actinobacteria,4FZHN@85025|Nocardiaceae	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Polyketide_cyc2
SRR25158390_k127_3648882_1	656024.FsymDg_2687	2.316e-221	717.0	COG2909@1|root,COG2909@2|Bacteria,2GM03@201174|Actinobacteria,4ETTY@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_3648882_33	1122238.AULR01000002_gene598	8.135e-34	139.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
SRR25158390_k127_3648882_5	479432.Sros_5878	5.488e-166	554.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4EHWC@85012|Streptosporangiales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158390_k127_3648882_11	298655.KI912266_gene5570	9.588e-119	389.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4EVXM@85013|Frankiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_3648882_35	1120950.KB892765_gene5674	3.289e-30	129.0	COG4636@1|root,COG4636@2|Bacteria,2IGTR@201174|Actinobacteria,4DRGB@85009|Propionibacteriales	201174|Actinobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158390_k127_3648882_16	1429046.RR21198_1177	2.383e-96	326.0	COG1752@1|root,COG1752@2|Bacteria,2HJ6N@201174|Actinobacteria,4G5HY@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_3672_5	1394178.AWOO02000050_gene6216	8.031e-55	202.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4EFM3@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158390_k127_3672_4	1313172.YM304_22030	1.956e-90	312.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158390_k127_3672_0	298654.FraEuI1c_2263	0.0	1068.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4ERSS@85013|Frankiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158390_k127_3672_3	1121877.JQKF01000016_gene125	4.932e-125	417.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CMTW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158390_k127_3672_2	67267.JNXT01000039_gene3460	4.525e-177	571.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_3672_7	1463820.JOGW01000011_gene3025	2.96e-29	130.0	COG0346@1|root,COG0346@2|Bacteria,2II0X@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3672_1	1229780.BN381_250102	8.464e-217	680.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX7N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3689758_5	1157638.KB892174_gene329	5.517e-17	88.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GMB6@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox,Pyr_redox_2
SRR25158390_k127_3689758_1	1313172.YM304_35130	7.308e-170	542.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria,4CNN3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158390_k127_3689758_4	1313172.YM304_35120	1.941e-22	102.0	COG0535@1|root,COG0535@2|Bacteria,2GQQT@201174|Actinobacteria	201174|Actinobacteria	S	Mycofactocin system	mftB	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3689758_0	1394178.AWOO02000017_gene6792	1.947e-203	638.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4EN8T@85012|Streptosporangiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_3689758_2	450851.PHZ_c1001	6.149e-129	426.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,2KFVB@204458|Caulobacterales	204458|Caulobacterales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_3689758_6	1429046.RR21198_1157	1.522e-06	55.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria,4FW42@85025|Nocardiaceae	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158390_k127_3689758_3	479431.Namu_3157	4.303e-32	135.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_3707554_0	450851.PHZ_c1807	7.081e-131	424.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2KIUB@204458|Caulobacterales	204458|Caulobacterales	C	Flavin-binding monooxygenase-like	-	-	1.14.13.84	ko:K14520	ko00363,ko01100,ko01120,map00363,map01100,map01120	-	R06892	RC01644	ko00000,ko00001,ko01000	-	-	-	-
SRR25158390_k127_3707554_3	1336249.JADW01000014_gene737	4.202e-26	123.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,4B72Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
SRR25158390_k127_3707554_2	58123.JOFJ01000006_gene151	8.809e-37	147.0	COG5592@1|root,COG5592@2|Bacteria,2GNJ6@201174|Actinobacteria,4EJ9R@85012|Streptosporangiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_3707554_1	1122611.KB904007_gene7764	1.743e-91	304.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3707554_4	1211815.CBYP010000063_gene1862	1.041e-23	108.0	COG0477@1|root,COG2814@2|Bacteria,2H1TJ@201174|Actinobacteria,4EUWV@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_3708977_1	28042.GU90_12025	2.351e-63	228.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4DZCB@85010|Pseudonocardiales	201174|Actinobacteria	EH	Reduction of activated sulfate into sulfite	cysH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2392	PAPS_reduct
SRR25158390_k127_3708977_0	671143.DAMO_1031	7.551e-141	468.0	COG0155@1|root,COG0155@2|Bacteria,2NPHB@2323|unclassified Bacteria	2|Bacteria	P	Nitrite and sulphite reductase 4Fe-4S domain	cysI	-	1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1	ko:K00362,ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00530,M00531	R00787,R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr
SRR25158390_k127_3708977_2	1323361.JPOC01000014_gene3706	3.156e-21	108.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4FVJA@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR25158390_k127_3748294_3	477641.MODMU_0246	3.864e-120	394.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6R@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3748294_0	1048339.KB913029_gene1969	0.0	1157.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_3748294_2	1048339.KB913029_gene1968	2.792e-121	408.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3748294_4	1123023.JIAI01000001_gene6499	9.906e-65	234.0	COG0329@1|root,COG0329@2|Bacteria,2IM0E@201174|Actinobacteria	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158390_k127_3748294_1	479433.Caci_8740	5.555e-171	551.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3763251_2	1089545.KB913037_gene1269	3.827e-100	334.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4DYEE@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158390_k127_3763251_0	100226.SCO1031	7.809e-253	805.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_3763251_1	285514.JNWO01000014_gene5553	5.653e-106	353.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3763251_3	1394178.AWOO02000088_gene963	8.553e-99	327.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHS4@85012|Streptosporangiales	201174|Actinobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_3763251_4	1123320.KB889562_gene6816	9.36e-83	294.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_3763251_5	929712.KI912613_gene949	5.224e-70	241.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4CSPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158390_k127_3763251_6	471852.Tcur_0070	6.667e-31	132.0	2EF32@1|root,338W5@2|Bacteria,2GMH3@201174|Actinobacteria,4EM1G@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Neocarzinostat
SRR25158390_k127_3775342_0	1382356.JQMP01000003_gene1431	6.447e-180	572.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_3775342_3	477641.MODMU_5496	7.246e-47	188.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_3775342_1	928724.SacglDRAFT_03632	1.563e-172	559.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4E1JU@85010|Pseudonocardiales	201174|Actinobacteria	E	decarboxylase	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158390_k127_3775342_2	525909.Afer_0459	1.239e-139	484.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_3775342_4	1229780.BN381_130043	1.112e-44	166.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,3UWCD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158390_k127_3790865_21	436229.JOEH01000001_gene1522	4.617e-41	167.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,2NETC@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158390_k127_3790865_7	103733.JNYO01000085_gene6	2.294e-104	354.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DYG2@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158390_k127_3790865_13	1313172.YM304_36430	3.188e-82	282.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158390_k127_3790865_18	1313172.YM304_19370	7.371e-51	190.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158390_k127_3790865_17	935866.JAER01000024_gene3108	3.246e-53	199.0	COG0095@1|root,COG0095@2|Bacteria,2GTPJ@201174|Actinobacteria	201174|Actinobacteria	H	Lipoate-protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3790865_27	411467.BACCAP_04418	6.615e-13	76.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,268ZM@186813|unclassified Clostridiales	186801|Clostridia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158390_k127_3790865_12	1313172.YM304_19390	2.913e-83	295.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CN25@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158390_k127_3790865_6	1229780.BN381_140013	1.939e-114	409.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,3UWG5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158390_k127_3790865_5	1313172.YM304_19420	2.807e-116	406.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CNID@84992|Acidimicrobiia	84992|Acidimicrobiia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	-	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_3790865_3	1229780.BN381_140011	2.773e-135	440.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,3UWA7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158390_k127_3790865_9	1313172.YM304_19440	3.282e-96	347.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CN07@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_3790865_11	1009370.ALO_17371	1.111e-83	293.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4H3RE@909932|Negativicutes	909932|Negativicutes	D	TIGRFAM stage V sporulation protein E, cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158390_k127_3790865_15	429009.Adeg_1564	2.665e-60	234.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,42F8I@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158390_k127_3790865_8	1313172.YM304_19470	1.184e-102	353.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CMTG@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_3790865_25	269800.Tfu_1112	1.113e-17	93.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4EJPJ@85012|Streptosporangiales	201174|Actinobacteria	M	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158390_k127_3790865_2	1229780.BN381_140005	5.599e-171	543.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,3UW88@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158390_k127_3790865_24	1218076.BAYB01000006_gene1094	2.561e-24	113.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1K3K8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158390_k127_3790865_16	1313172.YM304_19520	2.093e-58	211.0	COG0325@1|root,COG0325@2|Bacteria,2HGAF@201174|Actinobacteria,4CN9H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158390_k127_3790865_20	1229780.BN381_140002	3.168e-41	160.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,3UWTH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158390_k127_3790865_28	525909.Afer_1237	2.801e-11	67.0	COG0762@1|root,COG0762@2|Bacteria,2HGZP@201174|Actinobacteria,4CNZS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158390_k127_3790865_30	633147.Olsu_1088	1.637e-06	60.0	COG3599@1|root,COG3599@2|Bacteria,2HUP3@201174|Actinobacteria,4CV9A@84998|Coriobacteriia	84998|Coriobacteriia	D	DivIVA domain protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158390_k127_3790865_1	926569.ANT_22850	0.0	1060.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158390_k127_3790865_29	219305.MCAG_01205	7.473e-11	69.0	COG1872@1|root,COG1872@2|Bacteria,2GQSC@201174|Actinobacteria,4DEYI@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158390_k127_3790865_22	1229780.BN381_430080	1.003e-36	146.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158390_k127_3790865_23	1313172.YM304_19570	9.823e-28	121.0	COG0597@1|root,COG0597@2|Bacteria,2HGGT@201174|Actinobacteria,4CNE4@84992|Acidimicrobiia	84992|Acidimicrobiia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158390_k127_3790865_10	1313172.YM304_19580	1.171e-91	312.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CN1X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SRR25158390_k127_3790865_14	1313172.YM304_19590	2.155e-63	227.0	COG1959@1|root,COG1959@2|Bacteria,2HG5V@201174|Actinobacteria,4CN2Q@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158390_k127_3790865_4	1229780.BN381_430074	2.626e-127	423.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,3UWWP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158390_k127_3790865_19	981369.JQMJ01000003_gene7348	6.519e-48	177.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,2NGN5@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR25158390_k127_3790865_0	1229780.BN381_430072	0.0	1305.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,3UWBK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA polymerase alpha chain like domain	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158390_k127_3803778_0	1313172.YM304_10660	4.726e-167	529.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CMWB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158390_k127_3803778_5	1146883.BLASA_3916	8.03e-25	108.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria,4ET1J@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158390_k127_3803778_4	1038859.AXAU01000002_gene650	7.096e-56	211.0	COG1506@1|root,COG1506@2|Bacteria,1QU77@1224|Proteobacteria,2TWQ1@28211|Alphaproteobacteria,3JTXV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRR25158390_k127_3803778_6	67257.JODR01000016_gene4851	7.674e-16	89.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria	201174|Actinobacteria	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158390_k127_3803778_1	1229780.BN381_10054	2.43e-143	462.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,3UW6A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158390_k127_3803778_7	1313172.YM304_10730	7.72e-10	69.0	294NP@1|root,2ZS20@2|Bacteria,2H9SR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3803778_3	1229780.BN381_10056	1.579e-57	222.0	COG2214@1|root,COG2214@2|Bacteria,2H5PV@201174|Actinobacteria	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3803778_2	935839.JAGJ01000001_gene1033	9.385e-61	226.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4F4CP@85017|Promicromonosporaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158390_k127_3803778_8	675635.Psed_5853	3.203e-07	51.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4E1N9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase, IS111A IS1328 IS1533, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_3804876_5	1121877.JQKF01000048_gene761	1.832e-67	235.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4CNWF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158390_k127_3804876_7	469383.Cwoe_3147	6.686e-50	187.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158390_k127_3804876_16	1996.JOFO01000013_gene3362	9.597e-09	63.0	COG1366@1|root,COG1366@2|Bacteria,2II16@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
SRR25158390_k127_3804876_8	1123023.JIAI01000008_gene1418	2.73e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,2IKRF@201174|Actinobacteria,4E4DZ@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3804876_13	196162.Noca_4010	1.061e-30	126.0	COG5517@1|root,COG5517@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158390_k127_3804876_15	1121346.KB899831_gene740	1.085e-18	102.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,4HD33@91061|Bacilli,26VH7@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158390_k127_3804876_1	485913.Krac_6018	2.923e-115	388.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158390_k127_3804876_6	469383.Cwoe_3355	9.61e-66	233.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_3804876_3	326424.FRAAL4125	1.387e-82	283.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria	201174|Actinobacteria	P	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_3804876_4	1907.SGLAU_01360	1.36e-68	250.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158390_k127_3804876_10	37919.EP51_20925	4.646e-34	134.0	COG3070@1|root,COG3070@2|Bacteria,2IRAD@201174|Actinobacteria,4G6W8@85025|Nocardiaceae	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158390_k127_3804876_9	479432.Sros_8896	7.235e-35	142.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_3804876_12	479432.Sros_8897	2.331e-32	130.0	COG0640@1|root,COG0640@2|Bacteria,2ISNZ@201174|Actinobacteria,4EQ6F@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_3804876_11	298654.FraEuI1c_0868	7.26e-33	134.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4ET6E@85013|Frankiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_3804876_2	1205680.CAKO01000016_gene143	1.666e-88	303.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,2JRZM@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158390_k127_3804876_0	595536.ADVE02000001_gene1232	0.0	1292.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,36X8N@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158390_k127_3804876_14	1382358.JHVN01000005_gene3032	2.339e-28	123.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4I3DV@91061|Bacilli,21VVU@150247|Anoxybacillus	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_3804876_18	1120950.KB892815_gene6960	0.0002281	47.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4DRVY@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_380764_8	1273125.Rrhod_1653	1.025e-05	51.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4FU6G@85025|Nocardiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_380764_4	67315.JOBD01000018_gene7266	1.839e-63	228.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria	201174|Actinobacteria	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_380764_1	2002.JOEQ01000023_gene1256	2.166e-145	467.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4EIU6@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	yvbT	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_380764_6	234267.Acid_2001	6.638e-27	114.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_380764_5	1229780.BN381_90069	7.138e-51	196.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
SRR25158390_k127_380764_0	518766.Rmar_1486	1.494e-231	739.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158390_k127_380764_2	338966.Ppro_0566	1.202e-114	389.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,43TEH@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_380764_3	326427.Cagg_1702	1.013e-95	322.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,375DB@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_380764_7	266265.Bxe_B1418	2.588e-17	81.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VJNN@28216|Betaproteobacteria,1K12U@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_380768_11	196162.Noca_3219	2.454e-05	50.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4DRTJ@85009|Propionibacteriales	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158390_k127_380768_9	1313172.YM304_25990	4.206e-09	67.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158390_k127_380768_3	1313172.YM304_25980	3.629e-65	237.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CN3F@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158390_k127_380768_0	1229780.BN381_400030	2.885e-251	815.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,3UWB3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158390_k127_380768_4	1313172.YM304_25960	1.04e-33	137.0	COG1597@1|root,COG1597@2|Bacteria,2HCNI@201174|Actinobacteria	201174|Actinobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_380768_2	1229780.BN381_400028	6.112e-134	439.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	amiB1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_380768_1	1313172.YM304_25950	1.889e-239	751.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158390_k127_380768_7	1121877.JQKF01000002_gene1631	1.073e-11	78.0	2DDS5@1|root,2ZJ1Y@2|Bacteria,2HDMP@201174|Actinobacteria,4CP3T@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_380768_6	1229780.BN381_400023	9.077e-27	122.0	COG0454@1|root,COG0456@2|Bacteria,2HBQK@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_380768_5	1229780.BN381_400022	2.647e-27	117.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	MA20_42070	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_380768_10	1313172.YM304_25910	5.732e-07	51.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4CNVN@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_3837895_13	1120949.KB903303_gene6687	3.271e-19	89.0	COG1309@1|root,COG1309@2|Bacteria,2IHGM@201174|Actinobacteria,4DD7T@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3837895_6	656024.FsymDg_0294	2.08e-115	385.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4ESGU@85013|Frankiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158390_k127_3837895_12	477641.MODMU_1153	1.08e-20	98.0	2EPJR@1|root,33H6B@2|Bacteria,2GXK1@201174|Actinobacteria,4EWWU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3837895_5	1068978.AMETH_2735	3.667e-151	491.0	COG0389@1|root,COG0389@2|Bacteria,2GKHC@201174|Actinobacteria,4DZPZ@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158390_k127_3837895_2	471852.Tcur_3608	1.84e-190	611.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4EHD6@85012|Streptosporangiales	201174|Actinobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158390_k127_3837895_7	479432.Sros_1886	3.426e-101	342.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,4EKH5@85012|Streptosporangiales	201174|Actinobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158390_k127_3837895_10	1278073.MYSTI_02419	9.47e-45	173.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3837895_11	1463825.JNXC01000008_gene1357	1.635e-33	133.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_3837895_9	404589.Anae109_4239	2.454e-74	270.0	COG0654@1|root,COG0654@2|Bacteria,1R03K@1224|Proteobacteria,43CQQ@68525|delta/epsilon subdivisions,2X7Y6@28221|Deltaproteobacteria,2Z1K0@29|Myxococcales	28221|Deltaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_3837895_14	644283.Micau_1695	1.541e-18	99.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4DDIK@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3837895_8	671143.DAMO_2372	2.64e-93	336.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_3837895_0	1041930.Mtc_0042	2.163e-210	689.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,2NAFK@224756|Methanomicrobia	224756|Methanomicrobia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_3837895_4	882083.SacmaDRAFT_3251	1.887e-151	486.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4DYE3@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapX	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158390_k127_3837895_1	1283300.ATXB01000001_gene1702	5.397e-197	635.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XDT1@135618|Methylococcales	135618|Methylococcales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158390_k127_3837895_3	1123322.KB904691_gene4410	9.354e-163	516.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158390_k127_3840328_6	298654.FraEuI1c_3304	1.597e-181	574.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3840328_31	298654.FraEuI1c_4590	1.301e-56	215.0	COG1309@1|root,COG1309@2|Bacteria,2IFV0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3840328_28	1160137.KB907307_gene2806	5.621e-74	270.0	COG1960@1|root,COG1960@2|Bacteria,2GMTN@201174|Actinobacteria,4FUQK@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158390_k127_3840328_17	525368.HMPREF0591_4575	2.426e-111	382.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,233DU@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3840328_5	2002.JOEQ01000075_gene4072	7.758e-186	597.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria,4EMIB@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3840328_18	1380386.JIAW01000003_gene826	3.188e-109	360.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,234NC@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_3840328_3	298654.FraEuI1c_2475	4.542e-193	609.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4ETPN@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3840328_21	1219035.NT2_11_00180	4.608e-94	315.0	COG0235@1|root,COG0235@2|Bacteria,1PIZK@1224|Proteobacteria,2V86F@28211|Alphaproteobacteria,2K9KP@204457|Sphingomonadales	204457|Sphingomonadales	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158390_k127_3840328_37	298654.FraEuI1c_3297	5.488e-39	153.0	COG0346@1|root,COG0346@2|Bacteria,2IFSX@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158390_k127_3840328_24	13690.CP98_00468	1.905e-86	300.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3840328_27	298655.KI912266_gene2716	4.572e-80	280.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3840328_26	1122611.KB903957_gene56	1.837e-80	300.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ENP5@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3840328_2	58123.JOFJ01000021_gene3967	3.166e-216	693.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EFXA@85012|Streptosporangiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3840328_20	931627.MycrhDRAFT_6471	1.424e-94	343.0	COG1024@1|root,COG1024@2|Bacteria,2IBN1@201174|Actinobacteria,237N9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_3840328_16	1440774.Y900_012770	1.333e-116	388.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria,2371C@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3840328_33	1278073.MYSTI_04829	4.325e-45	182.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria	1224|Proteobacteria	K	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158390_k127_3840328_45	453591.Igni_0608	4.586e-08	64.0	COG0059@1|root,arCOG04465@2157|Archaea,2XQ0A@28889|Crenarchaeota	28889|Crenarchaeota	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158390_k127_3840328_22	1089545.KB913037_gene1318	2.084e-93	312.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4EBPH@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_3840328_29	1041522.MCOL_V218178	3.383e-73	254.0	COG1028@1|root,COG1028@2|Bacteria,2IB54@201174|Actinobacteria,235S1@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3840328_13	1265310.CCBD010000050_gene1934	5.454e-133	455.0	COG2124@1|root,COG2124@2|Bacteria,2I2QQ@201174|Actinobacteria,236CF@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_3840328_23	710686.Mycsm_06052	1.614e-86	311.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23D5F@1762|Mycobacteriaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_3840328_10	710686.Mycsm_06053	2.934e-140	471.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23CU1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_3840328_35	469383.Cwoe_2839	1.456e-43	169.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQG8@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_3840328_11	298654.FraEuI1c_3325	9.575e-139	458.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3840328_9	44454.NF84_07235	8.095e-168	535.0	COG1960@1|root,COG1960@2|Bacteria,2GP53@201174|Actinobacteria,234QY@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE17_2	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3840328_30	1265310.CCBD010000044_gene774	6.878e-60	233.0	COG1960@1|root,COG1960@2|Bacteria,2GIXH@201174|Actinobacteria,232QX@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
SRR25158390_k127_3840328_4	298654.FraEuI1c_3329	2.142e-191	627.0	COG0318@1|root,COG0318@2|Bacteria,2IEKP@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3840328_7	298654.FraEuI1c_3330	5.099e-180	602.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158390_k127_3840328_39	83332.Rv0728c	1.097e-26	121.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_3840328_40	362242.MUL_0823	2.963e-26	117.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_3840328_42	710686.Mycsm_01042	1.082e-13	80.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldolase	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.1.104,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K22130	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158390_k127_3840328_47	47839.CCAU010000004_gene1020	0.0009013	48.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldolase	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.1.104,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K22130	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158390_k127_3840328_32	926554.KI912672_gene16	2.259e-46	181.0	COG1063@1|root,COG1063@2|Bacteria,1WMH7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_3840328_36	525368.HMPREF0591_3836	2.567e-42	175.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_3840328_25	298653.Franean1_4041	6.237e-81	285.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3840328_19	298653.Franean1_4040	6.968e-103	344.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_3840328_0	298653.Franean1_4038	2.243e-277	869.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158390_k127_3840328_12	298653.Franean1_3676	4.022e-134	442.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_3840328_15	365528.KB891226_gene1281	1.567e-117	386.0	COG1028@1|root,COG1028@2|Bacteria,2GKJD@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_3840328_1	1206731.BAGB01000047_gene5493	2.587e-244	759.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4FUA0@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3840328_8	285535.JOEY01000006_gene8125	1.206e-171	553.0	COG3173@1|root,COG3173@2|Bacteria,2GJ58@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_3840328_46	309801.trd_A0089	0.0001391	53.0	COG0619@1|root,COG1122@1|root,COG0619@2|Bacteria,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27YU5@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158390_k127_3840328_43	1380390.JIAT01000009_gene1638	5.402e-12	77.0	COG0491@1|root,COG0491@2|Bacteria,2I9IC@201174|Actinobacteria,4CRBU@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3840328_44	526225.Gobs_1816	1.078e-10	74.0	2E10F@1|root,32WGJ@2|Bacteria,2IRR8@201174|Actinobacteria,4ET73@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3840328_34	1079986.JH164839_gene4486	1.157e-43	171.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_3840328_38	675635.Psed_5877	8.526e-29	120.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_3840328_41	1304865.JAGF01000001_gene1439	2.377e-14	80.0	COG1708@1|root,COG1708@2|Bacteria,2GUWM@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158390_k127_3840328_14	1229780.BN381_250102	5.646e-128	413.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX7N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3842602_6	882083.SacmaDRAFT_3051	4.064e-82	278.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4E2EF@85010|Pseudonocardiales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158390_k127_3842602_5	266117.Rxyl_0307	3.809e-86	297.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4CRQK@84995|Rubrobacteria	84995|Rubrobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_3842602_1	208444.JNYY01000015_gene3864	2.458e-156	512.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2IAWC@201174|Actinobacteria,4E22K@85010|Pseudonocardiales	201174|Actinobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18
SRR25158390_k127_3842602_10	479435.Kfla_5998	2.173e-52	190.0	COG0030@1|root,COG0030@2|Bacteria,2IMS8@201174|Actinobacteria,4DWR1@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
SRR25158390_k127_3842602_18	1283299.AUKG01000001_gene2158	4.825e-14	76.0	2B8TX@1|root,32240@2|Bacteria,2HRST@201174|Actinobacteria,4CTW1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3842602_8	644283.Micau_0845	3.78e-71	247.0	COG1994@1|root,COG1994@2|Bacteria,2I642@201174|Actinobacteria,4DMSP@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
SRR25158390_k127_3842602_16	1449353.JQMQ01000005_gene3372	1.805e-20	107.0	COG2146@1|root,COG2146@2|Bacteria,2IIR1@201174|Actinobacteria	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158390_k127_3842602_15	1268072.PSAB_06895	1.754e-22	107.0	COG0633@1|root,COG0633@2|Bacteria,1TTSR@1239|Firmicutes,4IJSR@91061|Bacilli,26Z4S@186822|Paenibacillaceae	91061|Bacilli	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
SRR25158390_k127_3842602_4	1122609.AUGT01000011_gene3561	7.039e-119	398.0	COG5424@1|root,COG5424@2|Bacteria,2I97U@201174|Actinobacteria	201174|Actinobacteria	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158390_k127_3842602_3	1068978.AMETH_6042	6.787e-119	400.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158390_k127_3842602_20	402626.Rpic_0077	6.324e-08	66.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VQ94@28216|Betaproteobacteria,1KGJJ@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_3842602_19	309801.trd_0794	4.359e-10	74.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi,27XIZ@189775|Thermomicrobia	189775|Thermomicrobia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158390_k127_3842602_12	1380394.JADL01000010_gene4275	3.417e-41	166.0	COG3193@1|root,COG3193@2|Bacteria,1RB2H@1224|Proteobacteria,2U7XA@28211|Alphaproteobacteria,2JU6J@204441|Rhodospirillales	204441|Rhodospirillales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158390_k127_3842602_2	882083.SacmaDRAFT_2689	5.904e-143	472.0	COG1012@1|root,COG1012@2|Bacteria,2GMNB@201174|Actinobacteria,4E9W9@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_3842602_13	1123519.PSJM300_07700	1.069e-35	154.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1RY5G@1236|Gammaproteobacteria,1Z3AP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_3842602_7	543632.JOJL01000035_gene5071	4.24e-82	281.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3842602_14	497965.Cyan7822_0545	1.753e-29	127.0	COG4106@1|root,COG4106@2|Bacteria,1GQ61@1117|Cyanobacteria,3KKTU@43988|Cyanothece	1117|Cyanobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_3842602_0	67267.JNXT01000014_gene310	2.246e-172	560.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158390_k127_3842602_17	263358.VAB18032_19810	1.55e-19	98.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4DENZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_3842602_11	1464048.JNZS01000027_gene1926	4.864e-44	172.0	COG1802@1|root,COG1802@2|Bacteria,2H1S8@201174|Actinobacteria,4DM6D@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_3842602_9	366394.Smed_5067	2.161e-57	207.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,4BE6T@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_384402_15	1172188.KB911820_gene2522	1.696e-07	61.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4FIWM@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_384402_8	1192034.CAP_1582	4.35e-66	244.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,43BQ1@68525|delta/epsilon subdivisions,2X718@28221|Deltaproteobacteria,2Z3MK@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR25158390_k127_384402_2	1343740.M271_03650	2.766e-129	437.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158390_k127_384402_5	1313172.YM304_24020	1.616e-100	352.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CNAM@84992|Acidimicrobiia	84992|Acidimicrobiia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158390_k127_384402_7	1313172.YM304_24030	4.222e-69	260.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CN6D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158390_k127_384402_14	756272.Plabr_0405	1.446e-24	121.0	COG1994@1|root,COG1994@2|Bacteria,2J0CK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158390_k127_384402_12	1229780.BN381_430043	1.014e-58	217.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,3UXCM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_384402_13	649831.L083_1906	1.35e-51	193.0	COG1208@1|root,COG1208@2|Bacteria,2IEN7@201174|Actinobacteria,4D963@85008|Micromonosporales	201174|Actinobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
SRR25158390_k127_384402_0	1313172.YM304_22570	1.035e-138	458.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CMPY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158390_k127_384402_10	1229780.BN381_450029	1.182e-62	226.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,3UWS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158390_k127_384402_11	1313172.YM304_22590	1.131e-61	221.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4CN0X@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_384402_4	882082.SaccyDRAFT_1801	3.623e-107	363.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4E0A0@85010|Pseudonocardiales	201174|Actinobacteria	M	Capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_384402_9	351607.Acel_1993	6.535e-66	239.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4ERX8@85013|Frankiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158390_k127_384402_3	1229780.BN381_80362	1.275e-118	394.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,3UWFF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158390_k127_384402_1	1313172.YM304_22610	1.415e-132	446.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CMYU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_384402_6	1229780.BN381_80368	1.152e-78	275.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,3UWJP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158390_k127_3851708_1	1229780.BN381_130069	6.396e-126	424.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,3UX2M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_3851708_0	1229780.BN381_130068	3.835e-138	470.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,3UX1Y@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_3851708_2	1313172.YM304_30260	9.843e-77	267.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
SRR25158390_k127_3851708_3	1229780.BN381_20127	2.9e-60	218.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,3UXF3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158390_k127_3851708_4	1121877.JQKF01000001_gene1333	4.233e-35	136.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4CMQ1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158390_k127_3853081_4	146922.JOFU01000062_gene89	5.521e-85	292.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_3853081_2	526225.Gobs_2584	3.569e-126	411.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_3853081_5	35754.JNYJ01000008_gene3224	5.52e-80	271.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4DM4I@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_3853081_7	1137268.AZXF01000015_gene701	2.909e-53	196.0	COG1309@1|root,COG1309@2|Bacteria,2IN8A@201174|Actinobacteria,4EJTA@85012|Streptosporangiales	201174|Actinobacteria	K	AefR-like transcriptional repressor, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
SRR25158390_k127_3853081_6	1194165.CAJF01000056_gene1501	3.915e-57	205.0	COG0454@1|root,COG0456@2|Bacteria,2I3PH@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_3853081_3	1123024.AUII01000022_gene148	7.512e-114	391.0	COG1541@1|root,COG1541@2|Bacteria,2HQ5P@201174|Actinobacteria,4E8WV@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158390_k127_3853081_8	675635.Psed_6275	6.833e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2GQPK@201174|Actinobacteria,4E4C2@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_3853081_0	1429046.RR21198_1227	0.0	1206.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FW35@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158390_k127_3853081_1	1429046.RR21198_1228	6.777e-217	680.0	COG1960@1|root,COG1960@2|Bacteria,2HHFP@201174|Actinobacteria,4FYH6@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
SRR25158390_k127_386695_7	675635.Psed_2003	4.274e-68	236.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4E0FZ@85010|Pseudonocardiales	201174|Actinobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158390_k127_386695_13	1121877.JQKF01000027_gene2453	2.531e-20	93.0	2ANAN@1|root,31D8Y@2|Bacteria,2HGVW@201174|Actinobacteria,4CNX0@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_386695_9	1380390.JIAT01000010_gene3557	2.915e-59	217.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria,4CPW5@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158390_k127_386695_3	1229780.BN381_80350	1.131e-123	414.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,3UX88@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	2.5.1.48,2.5.1.49,4.4.1.11	ko:K01739,ko:K01740,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01287,R01288,R02508,R03217,R03260,R04770,R04859,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02821,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158390_k127_386695_1	1313172.YM304_23840	7.381e-165	528.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4CNHB@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_386695_8	935866.JAER01000052_gene2866	1.444e-63	243.0	COG0827@1|root,COG0827@2|Bacteria,2HZT5@201174|Actinobacteria,4DSQJ@85009|Propionibacteriales	201174|Actinobacteria	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158390_k127_386695_10	408672.NBCG_02339	2.98e-42	161.0	COG0454@1|root,COG0456@2|Bacteria,2IMKI@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158390_k127_386695_6	1120950.KB892708_gene4333	4.641e-76	260.0	COG0494@1|root,COG0494@2|Bacteria,2GKUV@201174|Actinobacteria,4DRZ4@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_386695_2	1229780.BN381_80340	3.647e-140	459.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158390_k127_386695_11	1380390.JIAT01000009_gene927	4.941e-41	159.0	COG2114@1|root,COG2114@2|Bacteria,2ICJJ@201174|Actinobacteria,4CQDR@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158390_k127_386695_4	1449355.JQNR01000003_gene586	4.678e-96	321.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_386695_0	1120959.ATXF01000009_gene798	6.844e-217	694.0	COG1960@1|root,COG1960@2|Bacteria,2GJIB@201174|Actinobacteria,4FRFT@85023|Microbacteriaceae	201174|Actinobacteria	I	Acetyl-CoA dehydrogenase C-terminal like	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRR25158390_k127_386695_12	479433.Caci_8160	1.551e-39	160.0	COG1414@1|root,COG1414@2|Bacteria,2GP02@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158390_k127_386695_14	1078020.KEK_18148	1.751e-13	81.0	COG0179@1|root,COG0491@1|root,COG0179@2|Bacteria,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,2345Y@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	FAA_hydrolase,Lactamase_B
SRR25158390_k127_386695_15	367299.JOEE01000006_gene709	1.777e-11	76.0	2DTEY@1|root,33K2D@2|Bacteria,2HY25@201174|Actinobacteria,4FJFD@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_386695_5	365528.KB891208_gene2949	1.359e-94	330.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4ESDQ@85013|Frankiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158390_k127_3868632_0	1229780.BN381_100092	1.662e-204	645.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372,ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530,M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158390_k127_3868632_2	1229780.BN381_100091	1.553e-87	301.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11
SRR25158390_k127_3868632_4	1229780.BN381_100090	5.141e-46	183.0	COG0723@1|root,COG0723@2|Bacteria,2I02M@201174|Actinobacteria	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158390_k127_3868632_3	1229780.BN381_100088	1.111e-52	196.0	COG3448@1|root,COG3448@2|Bacteria,2IJXV@201174|Actinobacteria	201174|Actinobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
SRR25158390_k127_3868632_5	1229780.BN381_210091	7.642e-38	145.0	COG1848@1|root,COG1848@2|Bacteria,2H8GW@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_3868632_6	1229780.BN381_210092	2.181e-14	77.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158390_k127_3868632_1	1229780.BN381_210093	4.167e-175	557.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,3UXCB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3868632_7	1313172.YM304_30510	6.197e-14	85.0	296C4@1|root,2ZTMX@2|Bacteria,2HB9V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3888802_14	936455.KI421499_gene1353	4.906e-22	97.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,3JQR6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
SRR25158390_k127_3888802_6	713586.KB900536_gene529	5.172e-56	209.0	COG0309@1|root,COG0309@2|Bacteria,1N04A@1224|Proteobacteria,1SK12@1236|Gammaproteobacteria,1X0HN@135613|Chromatiales	135613|Chromatiales	O	PFAM AIR synthase related protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
SRR25158390_k127_3888802_3	1394178.AWOO02000020_gene7439	1.163e-99	334.0	COG1794@1|root,COG1794@2|Bacteria,2H7J9@201174|Actinobacteria,4EKYH@85012|Streptosporangiales	201174|Actinobacteria	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158390_k127_3888802_12	909613.UO65_5993	2.707e-34	150.0	COG1309@1|root,COG1309@2|Bacteria,2GPDP@201174|Actinobacteria,4E72Z@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3888802_2	469383.Cwoe_5739	6.669e-156	503.0	COG3239@1|root,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,4CRJF@84995|Rubrobacteria	84995|Rubrobacteria	CI	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
SRR25158390_k127_3888802_4	2074.JNYD01000034_gene6437	1.891e-93	313.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_3888802_0	1449069.JMLO01000035_gene2669	1.501e-195	631.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4FZU3@85025|Nocardiaceae	201174|Actinobacteria	P	Voltage gated chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158390_k127_3888802_13	35754.JNYJ01000077_gene7814	5.273e-30	127.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria,4DF2P@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158390_k127_3888802_9	222534.KB893717_gene2176	2.056e-47	188.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
SRR25158390_k127_3888802_5	1033730.CAHG01000014_gene1857	1.075e-60	213.0	arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria,4DSNX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3888802_11	471852.Tcur_1342	3.263e-41	155.0	COG0662@1|root,COG0662@2|Bacteria,2IMHT@201174|Actinobacteria,4EKA7@85012|Streptosporangiales	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,EutQ
SRR25158390_k127_3888802_10	1229780.BN381_130112	2.542e-42	169.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,3UWKY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Domain present in PSD-95, Dlg, and ZO-1/2.	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158390_k127_3888802_15	1128421.JAGA01000001_gene2460	1.322e-19	100.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158390_k127_3888802_7	1341646.CBMO010000116_gene2237	8.084e-54	196.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,2352Q@1762|Mycobacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158390_k127_3888802_8	1380356.JNIK01000016_gene3661	7.983e-49	194.0	2E9QE@1|root,333WR@2|Bacteria,2I2DC@201174|Actinobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3888802_1	675635.Psed_6255	1.222e-173	557.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E20H@85010|Pseudonocardiales	201174|Actinobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158390_k127_3888802_16	1214101.BN159_1178	4.367e-06	48.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_3925867_12	1229780.BN381_190004	1.026e-56	205.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,3UXM9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158390_k127_3925867_20	1298864.AUEQ01000001_gene4813	2.717e-19	98.0	COG0508@1|root,COG0508@2|Bacteria,2GQQK@201174|Actinobacteria,23A94@1762|Mycobacteriaceae	201174|Actinobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3925867_15	35754.JNYJ01000047_gene3541	2.635e-37	155.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4DDU9@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3925867_17	471852.Tcur_2560	1.231e-36	160.0	COG3226@1|root,COG3226@2|Bacteria,2HUE7@201174|Actinobacteria,4EQTR@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_3925867_3	471852.Tcur_2561	2.335e-198	657.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4EPGJ@85012|Streptosporangiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17,2.7.1.215,2.7.1.53	ko:K00854,ko:K00862,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00014	R01639,R01901,R07127,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_3925867_0	1370120.AUWR01000008_gene527	6.889e-236	742.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,23CIC@1762|Mycobacteriaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158390_k127_3925867_1	882083.SacmaDRAFT_1782	7.959e-225	704.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,4DXD6@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnA4	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158390_k127_3925867_10	405948.SACE_5354	2.518e-63	244.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4E32I@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158390_k127_3925867_4	266940.Krad_1634	1.512e-127	413.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_3925867_19	1229780.BN381_360028	4.564e-21	108.0	COG1555@1|root,COG1555@2|Bacteria,2IN8J@201174|Actinobacteria	201174|Actinobacteria	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
SRR25158390_k127_3925867_6	1123251.ATWM01000006_gene2136	1.655e-81	290.0	COG0515@1|root,COG0515@2|Bacteria,2HMAN@201174|Actinobacteria,4FJAC@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_3925867_21	483219.LILAB_05825	9.507e-16	88.0	2C5BM@1|root,32RFE@2|Bacteria,1Q9I2@1224|Proteobacteria,43E05@68525|delta/epsilon subdivisions,2WZBP@28221|Deltaproteobacteria,2Z1SM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3925867_13	234621.RER_06540	6.488e-44	168.0	2DR9N@1|root,33ATC@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
SRR25158390_k127_3925867_16	1123251.ATWM01000006_gene2137	4.296e-37	159.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3925867_7	1123023.JIAI01000002_gene4957	1.644e-80	298.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_3925867_2	1313172.YM304_41670	1.192e-218	710.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158390_k127_3925867_5	1313172.YM304_41680	3.561e-121	407.0	COG2175@1|root,COG2175@2|Bacteria,2I9TE@201174|Actinobacteria	201174|Actinobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158390_k127_3925867_9	711393.AYRX01000083_gene4764	6.018e-71	247.0	2B37N@1|root,31VVP@2|Bacteria,2GWAN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158390_k127_3925867_11	298654.FraEuI1c_5016	1.086e-62	230.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_3925867_8	298655.KI912267_gene7251	1.063e-72	263.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3925867_18	290400.Jann_3724	5.879e-35	144.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_11,Methyltransf_25
SRR25158390_k127_3925867_14	1440053.JOEI01000014_gene5139	1.391e-43	162.0	COG2334@1|root,COG2334@2|Bacteria,2GQ6F@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_3927017_0	1229780.BN381_150069	1.302e-310	962.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,3UX6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	B12 binding domain	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158390_k127_3927017_2	1048339.KB913029_gene4637	1.649e-89	300.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4EVRP@85013|Frankiales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158390_k127_3927017_4	35754.JNYJ01000005_gene5588	9.681e-38	151.0	2DA90@1|root,32TUY@2|Bacteria,2GKD0@201174|Actinobacteria,4DAT9@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3927017_1	1229780.BN381_100132	9.24e-117	381.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,3UX97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158390_k127_3927017_3	1229780.BN381_100131	6.857e-49	183.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158390_k127_3928313_0	1313172.YM304_26210	9.081e-206	653.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CMW5@84992|Acidimicrobiia	201174|Actinobacteria	CJ	CoA binding domain	acdA1	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_3928313_1	1229780.BN381_410013	5.682e-77	285.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,3UWTD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158390_k127_3928313_2	1240349.ANGC01000003_gene2028	5.432e-43	172.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4FXR3@85025|Nocardiaceae	201174|Actinobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158390_k127_3930931_3	1386969.AWTB01000048_gene3428	4.904e-36	151.0	COG0699@1|root,COG0699@2|Bacteria,2GNGP@201174|Actinobacteria,4GB92@85026|Gordoniaceae	201174|Actinobacteria	S	Dynamin family	iniA	GO:0003674,GO:0005215,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015562,GO:0016020,GO:0022857,GO:0030312,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_3930931_1	1123024.AUII01000008_gene1778	5.367e-105	373.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria,4DYHH@85010|Pseudonocardiales	201174|Actinobacteria	T	GTPases (dynamin-related)	iniC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_3930931_4	330214.NIDE3278	1.086e-27	130.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
SRR25158390_k127_3930931_5	1379698.RBG1_1C00001G0008	1.298e-22	108.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
SRR25158390_k127_3930931_0	926550.CLDAP_18130	1.567e-176	569.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
SRR25158390_k127_3930931_2	247490.KSU1_B0257	2.654e-70	242.0	COG0243@1|root,COG0243@2|Bacteria,2J2QN@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin
SRR25158390_k127_3939050_26	330084.JNYZ01000018_gene4218	1.611e-54	198.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZ47@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3939050_11	487521.OCU_13290	4.446e-126	415.0	COG2124@1|root,COG2124@2|Bacteria,2GNJI@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_3939050_37	298653.Franean1_4932	1.972e-21	109.0	2ECT0@1|root,336QK@2|Bacteria,2IKM4@201174|Actinobacteria,4ETIR@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3939050_14	1283283.ATXA01000001_gene378	6.195e-107	354.0	COG0300@1|root,COG0300@2|Bacteria,2I5VJ@201174|Actinobacteria,4EXE8@85013|Frankiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3939050_22	436229.JOEH01000021_gene7740	3.325e-69	259.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,2NEQ8@228398|Streptacidiphilus	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158390_k127_3939050_3	710421.Mycch_2953	5.984e-185	586.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2341M@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3939050_30	710421.Mycch_2954	1.218e-47	175.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria,23A1J@1762|Mycobacteriaceae	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_3939050_1	298654.FraEuI1c_3304	3.077e-200	631.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3939050_24	298654.FraEuI1c_4590	2.944e-60	226.0	COG1309@1|root,COG1309@2|Bacteria,2IFV0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3939050_33	298654.FraEuI1c_3297	9.02e-42	158.0	COG0346@1|root,COG0346@2|Bacteria,2IFSX@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158390_k127_3939050_19	1121422.AUMW01000009_gene3324	6.167e-86	304.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,262AS@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3939050_0	471852.Tcur_2177	4.062e-215	700.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EFXA@85012|Streptosporangiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3939050_13	298655.KI912266_gene4605	4.673e-116	386.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria,4EUW9@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_3939050_31	1278073.MYSTI_04829	5.803e-45	175.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria	1224|Proteobacteria	K	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158390_k127_3939050_27	795797.C497_04217	4.005e-54	209.0	COG0059@1|root,arCOG04465@2157|Archaea,2XTGU@28890|Euryarchaeota,23SZC@183963|Halobacteria	2157|Archaea	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158390_k127_3939050_18	749927.AMED_3831	1.038e-92	312.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4EBPH@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_3939050_21	487521.OCU_17190	2.455e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,2IB54@201174|Actinobacteria,235S1@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3939050_40	477641.MODMU_1118	6.531e-13	80.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria,4EVBK@85013|Frankiales	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,NAD_binding_8,Trp_halogenase
SRR25158390_k127_3939050_16	1172181.KB911736_gene2523	2.051e-95	317.0	COG0542@1|root,COG0542@2|Bacteria,2GKKF@201174|Actinobacteria	201174|Actinobacteria	O	Pfam Clp	clpC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR25158390_k127_3939050_34	1160718.SU9_26969	2.413e-34	137.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3939050_36	525368.HMPREF0591_2243	2.342e-24	106.0	2FG55@1|root,3481N@2|Bacteria,2I83I@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158390_k127_3939050_28	525368.HMPREF0591_2244	8.342e-53	192.0	COG1487@1|root,COG1487@2|Bacteria,2ISE2@201174|Actinobacteria,23B4F@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_3939050_41	118166.JH976538_gene5365	0.0006907	48.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G3GI@1117|Cyanobacteria,1H8II@1150|Oscillatoriales	1117|Cyanobacteria	CT	Ntpase (Nacht family)	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
SRR25158390_k127_3939050_35	1267534.KB906756_gene707	2.699e-30	122.0	2CIGD@1|root,2ZM6I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3939050_39	746697.Aeqsu_2661	2.185e-15	86.0	2CIGD@1|root,2ZM6I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3939050_38	1185876.BN8_01333	7.894e-17	90.0	2EGJ6@1|root,33ABD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3939050_29	471853.Bcav_1789	1.785e-51	190.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158390_k127_3939050_6	557599.MKAN_03655	2.405e-145	472.0	COG2124@1|root,COG2124@2|Bacteria,2I2QQ@201174|Actinobacteria,236CF@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_3939050_17	710686.Mycsm_06052	4.805e-93	330.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23D5F@1762|Mycobacteriaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_3939050_7	710686.Mycsm_06053	1.519e-143	466.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23CU1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_3939050_32	469383.Cwoe_2839	7.59e-43	170.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQG8@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_3939050_8	298654.FraEuI1c_3325	3.923e-143	469.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3939050_5	44454.NF84_07235	1.679e-168	537.0	COG1960@1|root,COG1960@2|Bacteria,2GP53@201174|Actinobacteria,234QY@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE17_2	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3939050_25	1265310.CCBD010000044_gene774	1.329e-55	218.0	COG1960@1|root,COG1960@2|Bacteria,2GIXH@201174|Actinobacteria,232QX@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
SRR25158390_k127_3939050_2	298654.FraEuI1c_3329	3.19e-187	615.0	COG0318@1|root,COG0318@2|Bacteria,2IEKP@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3939050_4	298654.FraEuI1c_3330	5.985e-178	598.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158390_k127_3939050_12	1265310.CCBD010000008_gene2799	1.407e-123	404.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_3939050_23	1265310.CCBD010000008_gene2798	2.106e-65	231.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldolase	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.1.104,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K22130	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158390_k127_3939050_9	525368.HMPREF0591_3836	2.072e-136	460.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_3939050_20	298653.Franean1_4041	3.826e-79	287.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3939050_15	298653.Franean1_4040	9.158e-101	350.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_3939050_10	298653.Franean1_4038	1.035e-129	422.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158390_k127_3939714_4	1489678.RDMS_02435	8.827e-116	387.0	COG0210@1|root,COG0210@2|Bacteria,1WI0I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF3553,UvrD-helicase,UvrD_C
SRR25158390_k127_3939714_8	882083.SacmaDRAFT_1509	3.794e-43	166.0	COG1902@1|root,COG1902@2|Bacteria,2IHUT@201174|Actinobacteria,4EC4H@85010|Pseudonocardiales	201174|Actinobacteria	C	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_3939714_0	1229780.BN381_60071	3.346e-246	794.0	COG2366@1|root,COG2366@2|Bacteria,2GMDM@201174|Actinobacteria	201174|Actinobacteria	S	Penicillin amidase	aac	GO:0005575,GO:0005576	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
SRR25158390_k127_3939714_6	1229780.BN381_30039	1.848e-63	220.0	COG4405@1|root,COG4405@2|Bacteria,2IFEU@201174|Actinobacteria,3UXF0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_3939714_1	1048339.KB913029_gene2528	8.802e-179	595.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_3939714_5	1394178.AWOO02000044_gene4450	1.458e-97	345.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EH5C@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3939714_2	28444.JODQ01000001_gene2611	2.113e-156	538.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158390_k127_3939714_3	1123355.JHYO01000031_gene1598	2.727e-130	428.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols	ligB	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158390_k127_3939714_9	1190603.AJYD01000011_gene2610	1.113e-42	161.0	COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,1S8CE@1236|Gammaproteobacteria,1XZ81@135623|Vibrionales	135623|Vibrionales	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
SRR25158390_k127_3939714_7	1116375.VEJY3_18091	3.559e-57	203.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1XVYI@135623|Vibrionales	135623|Vibrionales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158390_k127_3948733_5	986075.CathTA2_1252	8.126e-22	105.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli	91061|Bacilli	CO	Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158390_k127_3948733_2	1123024.AUII01000052_gene3914	6.211e-69	246.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_3948733_3	1048339.KB913029_gene2128	1.002e-64	252.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ETGG@85013|Frankiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158390_k127_3948733_4	1288083.AUKR01000014_gene2873	1.441e-24	121.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158390_k127_3948733_1	1246448.ANAZ01000046_gene4345	8.227e-123	403.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria	201174|Actinobacteria	EGP	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_3948733_0	926554.KI912625_gene639	7.573e-142	455.0	COG4864@1|root,COG4864@2|Bacteria,1WI32@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
SRR25158390_k127_3956123_0	1313172.YM304_22750	1.018e-166	530.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4CMX0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158390_k127_3956123_1	134676.ACPL_1455	4.33e-125	413.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158390_k127_3956123_3	479433.Caci_1803	2.348e-66	248.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158390_k127_3956123_2	479435.Kfla_5629	1.568e-83	294.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4DNU1@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158390_k127_3956123_6	426716.JOAJ01000007_gene4177	4.525e-14	77.0	COG1186@1|root,COG1186@2|Bacteria,2IFEJ@201174|Actinobacteria,4G0HV@85025|Nocardiaceae	201174|Actinobacteria	J	RF-1 domain	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158390_k127_3956123_5	68260.JOAY01000005_gene4906	7.245e-47	182.0	COG1670@1|root,COG1670@2|Bacteria,2IS6V@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158390_k127_3956123_4	1229780.BN381_330109	1.831e-58	206.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,3UW9K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158390_k127_3957577_1	285535.JOEY01000018_gene7513	1.126e-94	319.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158390_k127_3957577_4	1229780.BN381_300040	2.351e-64	241.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,3UXGB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158390_k127_3957577_7	1463900.JOIX01000019_gene36	5.527e-50	190.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158390_k127_3957577_2	1229780.BN381_300038	2.119e-86	296.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,3UXDP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	of an ABC-type transport system	-	-	-	-	-	-	-	-	-	-	-	-	OpuAC
SRR25158390_k127_3957577_5	1048339.KB913029_gene2808	2.406e-52	197.0	COG0785@1|root,COG0785@2|Bacteria,2I8T6@201174|Actinobacteria,4EVDM@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
SRR25158390_k127_3957577_10	1033730.CAHG01000008_gene3007	4.243e-24	110.0	COG0526@1|root,COG0526@2|Bacteria,2IMNX@201174|Actinobacteria,4DRHV@85009|Propionibacteriales	201174|Actinobacteria	CO	Redoxin	resA_1	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158390_k127_3957577_8	1229780.BN381_450041	2.766e-30	132.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR25158390_k127_3957577_3	1313172.YM304_38580	2.454e-72	248.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CN0M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158390_k127_3957577_6	1313172.YM304_38230	4.955e-50	188.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CN99@84992|Acidimicrobiia	84992|Acidimicrobiia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158390_k127_3957577_0	1229780.BN381_130286	5.817e-114	377.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,3UWXB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158390_k127_3957577_9	1048339.KB913029_gene4025	2.188e-26	113.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4ET4X@85013|Frankiales	201174|Actinobacteria	P	pfam abc	-	-	3.6.3.35	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00243,M00244,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
SRR25158390_k127_3982097_1	479432.Sros_3321	2.71e-89	299.0	COG0412@1|root,COG0412@2|Bacteria,2I37P@201174|Actinobacteria,4ER4Z@85012|Streptosporangiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158390_k127_3982097_0	518766.Rmar_2662	1.313e-138	456.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1FJ2X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_3982097_2	1068978.AMETH_1462	3.331e-74	264.0	COG0668@1|root,COG0668@2|Bacteria,2GJ51@201174|Actinobacteria,4DZ5F@85010|Pseudonocardiales	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158390_k127_3982097_3	469371.Tbis_0122	1.024e-58	211.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4E2XM@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158390_k127_3982097_4	585531.HMPREF0063_10826	1.163e-13	79.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4DP29@85009|Propionibacteriales	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158390_k127_3983200_4	1313172.YM304_37200	1.398e-22	112.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMPB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158390_k127_3983200_1	1125971.ASJB01000042_gene3657	2.291e-161	521.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158390_k127_3983200_2	1242864.D187_001075	9.486e-135	438.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,430G4@68525|delta/epsilon subdivisions,2WVMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3983200_0	1313172.YM304_00280	3.027e-180	575.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3983200_3	1313172.YM304_02680	4.289e-97	330.0	COG0258@1|root,COG0258@2|Bacteria,2H2A3@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease, C-terminal SAM fold	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158390_k127_3983200_5	644283.Micau_0717	5.704e-15	75.0	COG0638@1|root,COG0638@2|Bacteria,2HIHG@201174|Actinobacteria,4DGTX@85008|Micromonosporales	201174|Actinobacteria	O	20S proteasome	-	-	-	-	-	-	-	-	-	-	-	-	Proteasome
SRR25158390_k127_3984379_14	1240349.ANGC01000033_gene3023	1.014e-28	132.0	COG0515@1|root,COG3055@1|root,COG0515@2|Bacteria,COG3055@2|Bacteria,2HEN9@201174|Actinobacteria,4FVW7@85025|Nocardiaceae	201174|Actinobacteria	KLT	Galactose oxidase, central domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Kelch_1,Pkinase
SRR25158390_k127_3984379_7	1120949.KB903294_gene3836	1.473e-91	314.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4DEP9@85008|Micromonosporales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158390_k127_3984379_3	1463841.JOIR01000031_gene6416	2.259e-206	652.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_3984379_0	326424.FRAAL4738	5.905e-242	786.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EUMV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
SRR25158390_k127_3984379_2	1229780.BN381_80377	6.435e-227	713.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158390_k127_3984379_12	1229780.BN381_70129	2.95e-70	249.0	COG2345@1|root,COG2345@2|Bacteria,2GQ3A@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_3984379_17	1172179.AUKV01000009_gene4532	5.031e-16	92.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_3984379_22	1056816.JAFQ01000004_gene7132	0.0005948	42.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4G0IU@85025|Nocardiaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_3984379_16	405948.SACE_1886	1.698e-18	87.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4E5BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_3984379_1	1255043.TVNIR_1322	1.973e-228	723.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXRV@135613|Chromatiales	135613|Chromatiales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_3984379_11	446468.Ndas_4530	1.151e-70	246.0	COG1576@1|root,COG1576@2|Bacteria,2I47S@201174|Actinobacteria,4EPWB@85012|Streptosporangiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_3984379_21	1206737.BAGF01000035_gene1923	0.000233	51.0	COG1514@1|root,COG1514@2|Bacteria,2IFPP@201174|Actinobacteria,4G2MC@85025|Nocardiaceae	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158390_k127_3984379_20	525904.Tter_2546	1.302e-08	66.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3984379_18	1333523.L593_07795	1.308e-10	75.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23TI5@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3984379_15	479434.Sthe_2289	1.432e-21	109.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3984379_6	1283299.AUKG01000002_gene4966	4.918e-92	332.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158390_k127_3984379_10	1206731.BAGB01000027_gene2773	1.344e-79	285.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,4FXE2@85025|Nocardiaceae	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158390_k127_3984379_9	1229780.BN381_130179	1.218e-88	304.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_3984379_13	234621.RER_34100	6.442e-67	238.0	COG0332@1|root,COG0332@2|Bacteria,2IK61@201174|Actinobacteria,4FXDQ@85025|Nocardiaceae	201174|Actinobacteria	I	synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158390_k127_3984379_4	164757.Mjls_3425	2.561e-150	492.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,23EW9@1762|Mycobacteriaceae	201174|Actinobacteria	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158390_k127_3984379_5	479434.Sthe_1776	4.755e-150	511.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_3984379_19	266117.Rxyl_2945	7.021e-10	64.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158390_k127_3984379_8	479434.Sthe_1775	3.598e-89	301.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3998290_5	1313172.YM304_08760	2.238e-42	157.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CN4I@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158390_k127_3998290_2	1313172.YM304_08770	2.08e-71	252.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CNBD@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158390_k127_3998290_3	1313172.YM304_08800	7.697e-59	209.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CN26@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158390_k127_3998290_4	1229780.BN381_130024	1.385e-45	179.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,3UWN9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158390_k127_3998290_1	1313172.YM304_08820	2.107e-135	445.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CMWY@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158390_k127_3998290_0	1229780.BN381_130026	0.0	1210.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,3UWEV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158390_k127_3998290_6	1313172.YM304_08850	1.53e-29	134.0	COG0736@1|root,COG0736@2|Bacteria,2HGFC@201174|Actinobacteria,4CND0@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158390_k127_3999467_22	1229780.BN381_100168	1.616e-36	142.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,3UWB4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158390_k127_3999467_4	1229780.BN381_100166	3.665e-142	476.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,3UW7I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158390_k127_3999467_33	263358.VAB18032_04465	2.855e-07	60.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4DG12@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158390_k127_3999467_32	525909.Afer_2037	5.216e-08	61.0	2ASE6@1|root,31HTR@2|Bacteria,2HH1G@201174|Actinobacteria,4CP1Q@84992|Acidimicrobiia	84992|Acidimicrobiia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158390_k127_3999467_28	1123276.KB893267_gene5080	3.365e-20	97.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,47RUP@768503|Cytophagia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158390_k127_3999467_16	1229780.BN381_100163	1.185e-48	187.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,3UWKK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158390_k127_3999467_17	1313172.YM304_42870	6.001e-44	176.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CN3J@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
SRR25158390_k127_3999467_19	525909.Afer_2033	1.214e-38	153.0	COG0357@1|root,COG0357@2|Bacteria,2HGHA@201174|Actinobacteria,4CNEN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal RNA small subunit methyltransferase G	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158390_k127_3999467_6	1313172.YM304_42850	2.994e-118	391.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CMSR@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158390_k127_3999467_11	471852.Tcur_4977	2.023e-83	286.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4EG88@85012|Streptosporangiales	201174|Actinobacteria	K	ParB-like nuclease domain	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158390_k127_3999467_18	1172185.KB911513_gene4470	5.751e-40	153.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4G24Y@85025|Nocardiaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_3999467_3	525909.Afer_0030	3.188e-142	458.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CMUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_3999467_15	1313172.YM304_42760	3.954e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3999467_7	1229780.BN381_100154	3.061e-107	370.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,3UW9J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158390_k127_3999467_12	1313172.YM304_42740	5.124e-71	250.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CN2K@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158390_k127_3999467_30	1313172.YM304_42730	3.725e-13	83.0	2B0G0@1|root,31STG@2|Bacteria,2HGDS@201174|Actinobacteria,4CNCA@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3999467_25	525909.Afer_0025	1.333e-29	134.0	COG0454@1|root,COG0456@2|Bacteria,2HGG5@201174|Actinobacteria,4CNDG@84992|Acidimicrobiia	84992|Acidimicrobiia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_3999467_9	1313172.YM304_28170	2.309e-93	322.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CMXH@84992|Acidimicrobiia	84992|Acidimicrobiia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158390_k127_3999467_2	1157637.KB892093_gene6664	1.035e-161	521.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158390_k127_3999467_21	1229780.BN381_100148	2.5e-38	153.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158390_k127_3999467_10	1048339.KB913029_gene3593	5.554e-91	336.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4EVA5@85013|Frankiales	201174|Actinobacteria	T	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,PAS_3,PAS_4,PAS_9,SpoIIE
SRR25158390_k127_3999467_1	525909.Afer_0037	7.284e-170	554.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CNE8@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158390_k127_3999467_27	679197.HMPREF9336_01678	1.53e-21	103.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_3999467_26	1313172.YM304_42670	1.397e-28	122.0	2CQNK@1|root,332VM@2|Bacteria,2HGHQ@201174|Actinobacteria,4CNEW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR25158390_k127_3999467_5	1229780.BN381_100146	2.131e-125	436.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria	201174|Actinobacteria	M	penicillin-binding protein	ponA	GO:0001666,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0008144,GO:0008150,GO:0008658,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0033554,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0050896,GO:0051716,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0097159,GO:1901363,GO:1901681	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158390_k127_3999467_8	1229780.BN381_100144	5.107e-102	340.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,3UW6F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158390_k127_3999467_29	1313172.YM304_42660	3.863e-17	91.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158390_k127_3999467_23	1229780.BN381_100143	3.698e-32	128.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,3UWQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158390_k127_3999467_14	1229780.BN381_100142	3.201e-52	188.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158390_k127_3999467_24	1229780.BN381_100141	5.15e-32	130.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,3UWV6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158390_k127_3999467_20	1229780.BN381_100140	1.698e-38	156.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,3UWRZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158390_k127_3999467_0	436229.JOEH01000010_gene5333	1.509e-210	696.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,2NEZI@228398|Streptacidiphilus	201174|Actinobacteria	L	DnaB-like helicase N terminal domain	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158390_k127_3999467_13	1043493.BBLU01000004_gene2544	6.996e-66	229.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria	201174|Actinobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158390_k127_3999669_9	103733.JNYO01000004_gene7676	4.866e-12	66.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4DZDJ@85010|Pseudonocardiales	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158390_k127_3999669_7	1229780.BN381_130015	1.375e-25	108.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158390_k127_3999669_4	1229780.BN381_130016	5.783e-93	312.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,3UWG1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158390_k127_3999669_6	1313172.YM304_38910	3.027e-34	136.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3999669_0	1229780.BN381_130019	8.751e-292	913.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_3999669_8	1121877.JQKF01000003_gene1563	8.668e-14	81.0	COG2246@1|root,COG2246@2|Bacteria,2HGRJ@201174|Actinobacteria,4CNUB@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158390_k127_3999669_1	1210045.ALNP01000002_gene3863	9.874e-137	458.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158390_k127_3999669_2	1229780.BN381_130022	1.428e-119	396.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,3UWBB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	AIR synthase related protein, C-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_3999669_5	1313172.YM304_38880	7.751e-59	217.0	COG0461@1|root,COG0461@2|Bacteria,2HG8J@201174|Actinobacteria,4CN64@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_3999669_3	1329516.JPST01000036_gene3052	2.43e-107	363.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27BNG@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_4003566_3	471853.Bcav_0964	6.3e-05	54.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_4003566_0	314230.DSM3645_29316	2.668e-124	410.0	COG3588@1|root,COG3588@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR25158390_k127_4003566_2	1313172.YM304_13810	2.231e-90	327.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_3544 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4003566_1	1229780.BN381_10133	9.208e-123	411.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
SRR25158390_k127_4007860_5	345341.KUTG_04630	4.83e-25	116.0	COG3629@1|root,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria,4EDPY@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158390_k127_4007860_6	1445613.JALM01000036_gene2694	3.279e-20	100.0	COG1247@1|root,COG1247@2|Bacteria,2GR9D@201174|Actinobacteria,4EF6Z@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_4007860_3	1429046.RR21198_2274	1.1e-55	200.0	COG1576@1|root,COG1576@2|Bacteria,2I35D@201174|Actinobacteria,4GA0E@85025|Nocardiaceae	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_4007860_4	1056816.JAFQ01000004_gene814	4.306e-54	205.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4FU2W@85025|Nocardiaceae	201174|Actinobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SRR25158390_k127_4007860_0	1206720.BAFQ01000293_gene6387	4.739e-157	510.0	COG0318@1|root,COG0318@2|Bacteria,2GJYP@201174|Actinobacteria,4FVK2@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_4007860_2	298653.Franean1_1583	2.586e-85	302.0	COG4221@1|root,COG4221@2|Bacteria,2GK52@201174|Actinobacteria	201174|Actinobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_4007860_1	365528.KB891226_gene1281	3.412e-122	398.0	COG1028@1|root,COG1028@2|Bacteria,2GKJD@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_4069074_5	1229780.BN381_50138	2.813e-66	232.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,3UWP5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158390_k127_4069074_4	28444.JODQ01000001_gene2211	1.179e-105	362.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4EH29@85012|Streptosporangiales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158390_k127_4069074_1	1229780.BN381_50140	1.315e-161	519.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,3UWBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158390_k127_4069074_2	1313172.YM304_20450	1.366e-144	469.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CMXV@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158390_k127_4069074_0	1313172.YM304_20460	0.0	1526.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CMUA@84992|Acidimicrobiia	84992|Acidimicrobiia	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158390_k127_4069074_3	1313172.YM304_20470	2.57e-107	360.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CN0R@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158390_k127_4069074_6	1206732.BAGD01000279_gene6394	2.779e-55	214.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria,4G5VS@85025|Nocardiaceae	201174|Actinobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158390_k127_412868_6	1313172.YM304_15980	3.068e-06	51.0	COG0858@1|root,COG0858@2|Bacteria,2HGGX@201174|Actinobacteria,4CNEB@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158390_k127_412868_4	679197.HMPREF9336_02804	4.677e-14	75.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158390_k127_412868_1	1121428.DESHY_80091___1	1.171e-192	640.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158390_k127_412868_5	1179773.BN6_69830	2.827e-12	75.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,4E6Q8@85010|Pseudonocardiales	201174|Actinobacteria	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158390_k127_412868_2	1229780.BN381_330069	1.66e-153	512.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,3UW9A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158390_k127_412868_3	1229780.BN381_330068	1.91e-32	140.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,3UWYK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158390_k127_412868_0	298654.FraEuI1c_0363	2.472e-213	672.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4EUFB@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158390_k127_4144070_5	298655.KI912266_gene5856	2.36e-28	115.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GKFE@201174|Actinobacteria,4ESHW@85013|Frankiales	201174|Actinobacteria	C	PFAM Transketolase central region	bkdA	-	1.2.4.4	ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158390_k127_4144070_1	644283.Micau_0123	6.506e-96	323.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4DM4I@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_4144070_2	1380356.JNIK01000013_gene3972	1.228e-66	233.0	COG1960@1|root,COG1960@2|Bacteria,2IBHA@201174|Actinobacteria,4EX3H@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4144070_3	330084.JNYZ01000004_gene396	1.337e-61	229.0	COG1960@1|root,COG1960@2|Bacteria,2IBHA@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4144070_0	1173028.ANKO01000112_gene4816	2.039e-107	359.0	COG0235@1|root,COG0235@2|Bacteria,1G10W@1117|Cyanobacteria,1H8SZ@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158390_k127_4144070_7	1306174.JODP01000001_gene5053	4.019e-09	66.0	COG2207@1|root,COG2207@2|Bacteria,2GNMI@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
SRR25158390_k127_4144070_6	1121272.KB903253_gene6817	1.496e-19	95.0	COG1595@1|root,COG1595@2|Bacteria,2GWFT@201174|Actinobacteria,4DJEK@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_4144070_4	1380356.JNIK01000013_gene3976	2.083e-43	162.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4EV6C@85013|Frankiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_4145070_2	557599.MKAN_29030	1.445e-86	297.0	COG2124@1|root,COG2124@2|Bacteria,2HSPE@201174|Actinobacteria,2353U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_4145070_0	1122247.C731_4447	1.907e-144	463.0	COG1024@1|root,COG1024@2|Bacteria,2GKNU@201174|Actinobacteria,233FU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_4145070_1	298653.Franean1_2410	5.823e-134	454.0	COG1574@1|root,COG1574@2|Bacteria,2GKXR@201174|Actinobacteria,4ERSG@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158390_k127_4145070_3	285535.JOEY01000006_gene8164	3.322e-80	292.0	COG1804@1|root,COG1804@2|Bacteria,2I8FK@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_4145070_4	1343740.M271_49480	5.449e-35	149.0	COG1024@1|root,COG1024@2|Bacteria,2HSJH@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_4153575_0	1313172.YM304_16360	1.889e-192	610.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CMRP@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT,Malic_M,malic
SRR25158390_k127_4153575_1	479432.Sros_8119	5.521e-134	445.0	COG1231@1|root,COG1231@2|Bacteria,2GMV0@201174|Actinobacteria,4EFGX@85012|Streptosporangiales	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158390_k127_4153575_2	1127134.NOCYR_2237	2.49e-76	265.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4FVN0@85025|Nocardiaceae	201174|Actinobacteria	S	Methyltransferase small domain	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158390_k127_4153575_7	1048339.KB913029_gene2630	9.098e-18	91.0	COG0346@1|root,COG0346@2|Bacteria,2IQJB@201174|Actinobacteria,4EX4Q@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4153575_9	485913.Krac_9827	7.813e-05	49.0	arCOG13241@1|root,2ZEFN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4153575_6	266265.Bxe_C0680	1.743e-21	96.0	COG2161@1|root,COG2161@2|Bacteria,1N8EM@1224|Proteobacteria,2VUQY@28216|Betaproteobacteria,1K9QE@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158390_k127_4153575_4	1229780.BN381_20045	3.005e-51	188.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158390_k127_4153575_8	1120936.KB907208_gene922	2.775e-12	76.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158390_k127_4153575_5	351607.Acel_1691	5.849e-35	142.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4ESZD@85013|Frankiales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158390_k127_4153575_3	222534.KB893783_gene5258	2.409e-61	225.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4ESN0@85013|Frankiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158390_k127_4264364_0	1313172.YM304_35460	4.552e-319	988.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158390_k127_4264364_3	1157634.KB912943_gene4129	2.075e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_4264364_2	1313172.YM304_35500	3.897e-77	274.0	COG1565@1|root,COG1565@2|Bacteria	2|Bacteria	P	acr, cog1565	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158390_k127_4264364_1	1229780.BN381_160034	6.665e-164	527.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,3UWFY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_4272610_10	179408.Osc7112_0435	3.66e-20	106.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
SRR25158390_k127_4272610_0	344747.PM8797T_18941	3.756e-255	805.0	COG2192@1|root,COG2192@2|Bacteria,2IYCS@203682|Planctomycetes	203682|Planctomycetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158390_k127_4272610_12	886293.Sinac_7434	6.26e-15	81.0	2BR4A@1|root,32K29@2|Bacteria,2J1BQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4272610_13	243090.RB10884	1.147e-11	67.0	2EGPU@1|root,32K36@2|Bacteria,2J1G1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4272610_1	653045.Strvi_1813	4.813e-255	809.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158390_k127_4272610_3	1089545.KB913037_gene9525	4.041e-161	529.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158390_k127_4272610_7	1229780.BN381_250088	8.014e-113	396.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158390_k127_4272610_9	1136417.AZWE01000005_gene4658	7.526e-71	258.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,4DGHU@85008|Micromonosporales	201174|Actinobacteria	M	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_4272610_6	1068978.AMETH_4853	3.531e-113	379.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4DZK5@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158390_k127_4272610_4	1127134.NOCYR_2075	7.72e-155	507.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4FU1D@85025|Nocardiaceae	201174|Actinobacteria	M	ABC transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158390_k127_4272610_5	1229780.BN381_310034	3.977e-137	454.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,3UWGU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158390_k127_4272610_2	1313172.YM304_18610	1.709e-171	551.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria	201174|Actinobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA,TspO_MBR
SRR25158390_k127_4272610_8	1380386.JIAW01000032_gene3485	3.636e-95	322.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,234S5@1762|Mycobacteriaceae	201174|Actinobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158390_k127_4272610_11	1127134.NOCYR_2782	1.925e-18	92.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4G0AJ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4286174_36	1116369.KB890024_gene231	4.265e-24	102.0	COG0601@1|root,COG0601@2|Bacteria,1MW3U@1224|Proteobacteria,2TUR2@28211|Alphaproteobacteria,43P07@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_4286174_15	1122132.AQYH01000007_gene1997	1.215e-97	332.0	COG1173@1|root,COG1173@2|Bacteria,1MXGS@1224|Proteobacteria,2TTQ7@28211|Alphaproteobacteria,4BMGF@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_4286174_12	1121289.JHVL01000031_gene343	2.882e-106	368.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_4286174_3	1116369.KB890024_gene228	2.413e-144	467.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2U1HV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_4286174_24	1313172.YM304_23250	3.703e-60	230.0	COG0730@1|root,COG0730@2|Bacteria,2HGFT@201174|Actinobacteria,4CNDC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_4286174_20	1121033.AUCF01000032_gene2622	7.993e-82	287.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2JPDU@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158390_k127_4286174_29	326424.FRAAL6172	3.581e-45	175.0	COG1802@1|root,COG1802@2|Bacteria,2IDZ6@201174|Actinobacteria,4ET86@85013|Frankiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_4286174_37	981369.JQMJ01000004_gene4589	6.846e-11	66.0	2981C@1|root,2ZV7E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4286174_2	457429.ABJI02000385_gene4491	8.78e-180	578.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_4286174_17	1449976.KALB_1770	5.897e-92	336.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria,4E9J0@85010|Pseudonocardiales	201174|Actinobacteria	T	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158390_k127_4286174_23	28042.GU90_02820	4.29e-76	261.0	COG4221@1|root,COG4221@2|Bacteria,2HZEI@201174|Actinobacteria,4DXAX@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_4286174_27	1504822.CCNO01000014_gene1110	2.751e-58	216.0	COG1191@1|root,COG1191@2|Bacteria	2|Bacteria	K	sigma factor activity	sigB	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006629,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032774,GO:0033554,GO:0034059,GO:0034641,GO:0034645,GO:0034654,GO:0036293,GO:0042221,GO:0042594,GO:0043170,GO:0043175,GO:0043254,GO:0043562,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090,ko:K03091,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_4286174_21	446468.Ndas_1578	7.617e-79	276.0	COG1216@1|root,COG1216@2|Bacteria,2GKS6@201174|Actinobacteria,4EIPY@85012|Streptosporangiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_4286174_8	1476583.DEIPH_ctg011orf0137	1.329e-123	409.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158390_k127_4286174_22	1540221.JQNI01000004_gene331	1.318e-76	271.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158390_k127_4286174_16	649831.L083_2431	1.556e-95	326.0	COG0535@1|root,COG0535@2|Bacteria,2H1J8@201174|Actinobacteria	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158390_k127_4286174_18	711393.AYRX01000077_gene636	2.121e-91	317.0	COG1216@1|root,COG1216@2|Bacteria,2I30N@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_4286174_32	665577.JH993789_gene6400	2.027e-41	176.0	COG2208@1|root,COG2208@2|Bacteria,2GKG3@201174|Actinobacteria	201174|Actinobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2,PAS_3,PAS_4,SpoIIE
SRR25158390_k127_4286174_0	1380370.JIBA01000011_gene3250	5.19e-228	718.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4FIVH@85021|Intrasporangiaceae	201174|Actinobacteria	O	Carbamoyltransferase C-terminus	nolO	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158390_k127_4286174_11	1380390.JIAT01000010_gene4057	1.636e-109	372.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2GKU1@201174|Actinobacteria,4CRDH@84995|Rubrobacteria	84995|Rubrobacteria	H	Cytidylyltransferase-like	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158390_k127_4286174_28	1123322.KB904691_gene4434	2.935e-53	209.0	COG0279@1|root,COG0279@2|Bacteria,2IIGW@201174|Actinobacteria	201174|Actinobacteria	G	phosphoheptose isomerase	gmhA	-	2.7.7.71,5.3.1.28	ko:K03271,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769,R09772	RC00002,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158390_k127_4286174_4	1211815.CBYP010000030_gene1291	3.764e-139	471.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4EUJN@85013|Frankiales	201174|Actinobacteria	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_4286174_19	909613.UO65_1427	1.27e-86	306.0	COG0859@1|root,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria,4DYGA@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
SRR25158390_k127_4286174_26	266117.Rxyl_0716	2.402e-58	208.0	COG0241@1|root,COG1216@1|root,COG0241@2|Bacteria,COG1216@2|Bacteria,2GK77@201174|Actinobacteria,4CQSE@84995|Rubrobacteria	84995|Rubrobacteria	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_2,Hydrolase_like
SRR25158390_k127_4286174_5	1223521.BBJX01000002_gene2736	2.792e-132	451.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VKC7@28216|Betaproteobacteria,4ABMY@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
SRR25158390_k127_4286174_13	469371.Tbis_2001	3.864e-103	350.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4E02U@85010|Pseudonocardiales	201174|Actinobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113,5.5.1.1	ko:K01856,ko:K02549	ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220	M00116,M00568	R04031,R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01053,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158390_k127_4286174_6	215803.DB30_6509	9.199e-129	418.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2YZQB@29|Myxococcales	28221|Deltaproteobacteria	J	SEC-C motif	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
SRR25158390_k127_4286174_14	1229780.BN381_360005	4.111e-102	346.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158390_k127_4286174_31	479431.Namu_0023	6.07e-42	160.0	2BG65@1|root,32A2Y@2|Bacteria,2IRVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4286174_7	469383.Cwoe_1487	9.722e-125	414.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4CPIN@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158390_k127_4286174_35	1123024.AUII01000015_gene3758	9.85e-25	104.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SRR25158390_k127_4286174_9	1122611.KB903956_gene211	7.428e-123	407.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4EHBH@85012|Streptosporangiales	201174|Actinobacteria	S	Reductase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
SRR25158390_k127_4286174_34	561175.KB894101_gene4560	1.327e-25	117.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,4EI2H@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_4286174_30	479432.Sros_1912	3.283e-44	171.0	COG2917@1|root,COG2917@2|Bacteria,2IGTQ@201174|Actinobacteria,4EIRE@85012|Streptosporangiales	201174|Actinobacteria	D	probably involved in intracellular septation	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159,IspA
SRR25158390_k127_4286174_1	1229780.BN381_250091	4.167e-220	711.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,3UWD9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158390_k127_4286174_25	306281.AJLK01000102_gene3405	4.008e-60	213.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4286174_10	1205680.CAKO01000040_gene852	4.778e-114	381.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2JPGW@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158390_k127_4286174_33	525909.Afer_0695	6.721e-38	151.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4CNCN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_430945_1	1089453.GOSPT_051_00830	2.595e-160	514.0	COG0160@1|root,COG0160@2|Bacteria,2GKUY@201174|Actinobacteria,4GARU@85026|Gordoniaceae	201174|Actinobacteria	E	Aminotransferase class-III	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_430945_3	1120936.KB907210_gene5608	2.096e-32	142.0	COG0454@1|root,COG0456@2|Bacteria,2IMKZ@201174|Actinobacteria,4EPAB@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ectA	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_430945_4	1380356.JNIK01000003_gene1217	2.873e-12	74.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158390_k127_430945_2	471852.Tcur_1028	1.586e-46	173.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4EIQN@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_430945_0	471852.Tcur_1029	2.102e-271	851.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4EHBK@85012|Streptosporangiales	201174|Actinobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158390_k127_43148_5	1172186.KB911468_gene921	1.495e-26	112.0	COG2020@1|root,COG2020@2|Bacteria,2GN9N@201174|Actinobacteria,2336J@1762|Mycobacteriaceae	201174|Actinobacteria	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
SRR25158390_k127_43148_1	439235.Dalk_1526	2.838e-110	397.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158390_k127_43148_4	326427.Cagg_0545	1.139e-28	122.0	COG2010@1|root,COG2010@2|Bacteria,2G6R3@200795|Chloroflexi,377DZ@32061|Chloroflexia	32061|Chloroflexia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SRR25158390_k127_43148_3	1312959.KI914641_gene1315	1.544e-56	205.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria,1WBYY@1268|Micrococcaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158390_k127_43148_2	1385519.N801_18820	7.033e-58	216.0	2A4DI@1|root,30SZC@2|Bacteria,2GJJM@201174|Actinobacteria,4FESI@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_43148_7	1530186.JQEY01000001_gene736	7.56e-10	68.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158390_k127_43148_8	1032480.MLP_33830	0.0001167	48.0	2DREV@1|root,33BF4@2|Bacteria,2ISW7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_43148_6	656024.FsymDg_3168	5.405e-26	112.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_43148_0	937777.Deipe_2634	3.899e-127	424.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR25158390_k127_4316897_5	1121877.JQKF01000011_gene378	2.577e-57	206.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTP@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_4316897_2	164757.Mjls_4712	2.987e-79	301.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,23435@1762|Mycobacteriaceae	201174|Actinobacteria	EI	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158390_k127_4316897_0	1229780.BN381_150046	6.109e-243	764.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,3UX3B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	ccrA	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_4316897_3	1172179.AUKV01000005_gene5726	1.012e-65	237.0	COG2267@1|root,COG2267@2|Bacteria,2I4WD@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_4316897_8	1464048.JNZS01000004_gene1571	2.961e-09	66.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_4316897_7	1172188.KB911820_gene2522	2.512e-26	122.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4FIWM@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_4316897_4	1229780.BN381_150047	1.981e-58	207.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,3UWVQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158390_k127_4316897_6	710421.Mycch_3962	1.94e-55	206.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,234NT@1762|Mycobacteriaceae	201174|Actinobacteria	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_4316897_1	326424.FRAAL4544	2.905e-141	466.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4ES5N@85013|Frankiales	201174|Actinobacteria	S	PFAM ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158390_k127_4327894_0	37919.EP51_13270	3.233e-70	243.0	COG3832@1|root,COG3832@2|Bacteria,2IE7C@201174|Actinobacteria,4FX1H@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_4327894_1	1179773.BN6_26250	5.598e-41	166.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4E4WI@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_4327894_3	471852.Tcur_2353	1.072e-13	78.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4327894_2	1214101.BN159_7501	1.18e-39	163.0	COG1670@1|root,COG1670@2|Bacteria,2HNQP@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158390_k127_4327894_4	768710.DesyoDRAFT_4987	1.142e-12	75.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,261M7@186807|Peptococcaceae	186801|Clostridia	S	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158390_k127_4331681_10	2002.JOEQ01000015_gene5127	1.031e-14	82.0	COG2267@1|root,COG2267@2|Bacteria,2I94I@201174|Actinobacteria,4EPHD@85012|Streptosporangiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_4331681_5	1146883.BLASA_1402	4.795e-93	336.0	COG3284@1|root,COG3284@2|Bacteria	2|Bacteria	KQ	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,Sigma54_activ_2
SRR25158390_k127_4331681_2	314256.OG2516_16029	1.138e-194	637.0	COG1129@1|root,COG1129@2|Bacteria,1PF40@1224|Proteobacteria,2V7FI@28211|Alphaproteobacteria,2PF7J@252301|Oceanicola	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158390_k127_4331681_4	314256.OG2516_16034	8.216e-119	394.0	COG1879@1|root,COG1879@2|Bacteria,1PI95@1224|Proteobacteria,2VD0X@28211|Alphaproteobacteria,2PFP9@252301|Oceanicola	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
SRR25158390_k127_4331681_8	1122214.AQWH01000008_gene1568	5.286e-73	259.0	COG1172@1|root,COG1172@2|Bacteria,1MX1K@1224|Proteobacteria,2TUYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158390_k127_4331681_0	1123023.JIAI01000003_gene2806	2.942e-237	749.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4EA6K@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
SRR25158390_k127_4331681_7	1283283.ATXA01000001_gene1281	2.47e-74	275.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,4EVMJ@85013|Frankiales	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158390_k127_4331681_6	471857.Svir_13060	2.796e-82	281.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4DZJ6@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4331681_9	1549858.MC45_16640	1.531e-48	180.0	28PSM@1|root,2ZCE4@2|Bacteria,1RBR6@1224|Proteobacteria,2V0GH@28211|Alphaproteobacteria,2K9CV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4331681_3	555793.WSK_3094	1.051e-141	457.0	28IZD@1|root,2Z8WU@2|Bacteria,1NEGQ@1224|Proteobacteria,2UZGH@28211|Alphaproteobacteria,2K8TY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4331681_1	381666.H16_B1939	9.366e-201	637.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39,1.2.1.8	ko:K00130,ko:K00146	ko00260,ko00360,ko00643,ko01100,ko01120,map00260,map00360,map00643,map01100,map01120	M00555	R02536,R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_4332669_2	1034769.KB910518_gene460	7.481e-08	67.0	COG1216@1|root,COG1216@2|Bacteria,1V5TD@1239|Firmicutes,4IPP5@91061|Bacilli,2761C@186822|Paenibacillaceae	91061|Bacilli	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_4332669_0	1158292.JPOE01000002_gene3210	1.402e-50	208.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria	1224|Proteobacteria	E	Glycosyl transferase, family 2	-	-	2.4.1.175,2.4.1.226	ko:K13500	ko00532,ko01100,map00532,map01100	-	R04603,R05931,R05932,R05933,R05934,R07336	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_transf_7C,Glycos_transf_2
SRR25158390_k127_4332669_1	1249627.D779_3067	2.434e-44	187.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1WXWS@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
SRR25158390_k127_4334980_2	1313172.YM304_25140	2.294e-152	504.0	28TMQ@1|root,33S62@2|Bacteria,2H3TK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4334980_4	1229780.BN381_310090	1.518e-123	415.0	COG1807@1|root,COG1835@1|root,COG1807@2|Bacteria,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	aftB	GO:0008150,GO:0040007	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	Acyl_transf_3,PMT_2
SRR25158390_k127_4334980_7	1306174.JODP01000013_gene7397	2.362e-74	259.0	COG0463@1|root,COG0463@2|Bacteria,2IPT1@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158390_k127_4334980_1	479435.Kfla_1557	1.509e-166	550.0	COG0421@1|root,COG0421@2|Bacteria,2HZ8A@201174|Actinobacteria,4DR1S@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158390_k127_4334980_6	1229780.BN381_10225	4.213e-78	274.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158390_k127_4334980_3	1229780.BN381_50074	1.429e-137	453.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria,3UXFI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_4334980_0	656024.FsymDg_2137	0.0	1110.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRR25158390_k127_4334980_5	1313172.YM304_34920	7.931e-82	277.0	COG4502@1|root,COG4502@2|Bacteria,2IAHF@201174|Actinobacteria	201174|Actinobacteria	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
SRR25158390_k127_4334980_8	365528.KB891181_gene4741	4.415e-23	100.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_1,Glycos_transf_2
SRR25158390_k127_4375363_3	164757.Mjls_3416	3.603e-153	491.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,237XV@1762|Mycobacteriaceae	201174|Actinobacteria	S	alcohol dehydrogenase	sadh	-	1.1.1.1	ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_4375363_1	1229780.BN381_310021	7.877e-187	598.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,3UXSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_4375363_5	298655.KI912266_gene5537	8.728e-128	419.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4375363_4	1229780.BN381_310008	2.508e-135	439.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_4375363_0	298654.FraEuI1c_1929	7.3e-190	608.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA_1	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_4375363_8	882086.SacxiDRAFT_1372	1.42e-28	123.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4E5BM@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR
SRR25158390_k127_4375363_7	419947.MRA_0285	4.431e-42	160.0	COG1848@1|root,COG1848@2|Bacteria,2ITEJ@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_4375363_9	419947.MRA_0756	4.867e-17	83.0	2DDJC@1|root,2ZIAU@2|Bacteria,2HABV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_4375363_6	1122611.KB903940_gene2047	9.055e-57	217.0	COG0477@1|root,COG2814@2|Bacteria,2I8TX@201174|Actinobacteria,4EMS8@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_4375363_2	1123320.KB889662_gene1623	1.699e-184	580.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_4383101_0	1223544.GSI01S_15_01330	3.897e-112	374.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4GASI@85026|Gordoniaceae	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158390_k127_4383101_3	397945.Aave_3987	2.231e-40	161.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,4AAA8@80864|Comamonadaceae	28216|Betaproteobacteria	Q	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158390_k127_4383101_1	1380370.JIBA01000012_gene3724	1.457e-50	193.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4FG38@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4383101_5	570952.ATVH01000003_gene705	4.779e-17	86.0	COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,2UMJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158390_k127_4383101_4	1122622.ATWJ01000002_gene795	1.399e-30	127.0	COG1733@1|root,COG1733@2|Bacteria,2IRHS@201174|Actinobacteria,4FI6I@85021|Intrasporangiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_4383101_2	1122622.ATWJ01000002_gene794	1.03e-40	169.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_4390563_3	1116375.VEJY3_18091	1.393e-128	414.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1XVYI@135623|Vibrionales	135623|Vibrionales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158390_k127_4390563_5	649831.L083_3805	5.257e-78	275.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4DCVQ@85008|Micromonosporales	201174|Actinobacteria	H	Aldolase/RraA	ligK	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR25158390_k127_4390563_6	566466.NOR53_932	1.466e-70	248.0	COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,1RW94@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
SRR25158390_k127_4390563_7	926564.KI911697_gene291	2.622e-45	184.0	COG1802@1|root,COG1802@2|Bacteria,2IBT4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_4390563_2	1190603.AJYD01000011_gene2608	4.392e-130	423.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XW82@135623|Vibrionales	135623|Vibrionales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
SRR25158390_k127_4390563_1	1469613.JT55_07845	5.874e-159	511.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	4-hydroxybenzoate	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR25158390_k127_4390563_4	1121933.AUHH01000003_gene1334	1.721e-113	374.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DQPN@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4390563_0	1120949.KB903294_gene3609	1.074e-187	592.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4DHUA@85008|Micromonosporales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158390_k127_4390563_9	1123368.AUIS01000001_gene1864	8.929e-10	70.0	COG1315@1|root,COG1315@2|Bacteria	2|Bacteria	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
SRR25158390_k127_4390563_8	1229780.BN381_310058	6.16e-33	143.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_4406713_12	105422.BBPM01000015_gene2053	3.256e-87	294.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,2I36T@201174|Actinobacteria,2NNH8@228398|Streptacidiphilus	201174|Actinobacteria	M	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_4406713_8	1158050.KB895474_gene2838	5.633e-121	407.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158390_k127_4406713_10	100226.SCO7628	3.107e-89	312.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
SRR25158390_k127_4406713_11	591157.SSLG_05992	1.098e-87	303.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158390_k127_4406713_1	1313172.YM304_13260	1.166e-186	589.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNIG@84992|Acidimicrobiia	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4406713_9	882086.SacxiDRAFT_2974	8.748e-91	311.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria,4DZR3@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_4406713_5	298654.FraEuI1c_0422	9.978e-138	450.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria	201174|Actinobacteria	Q	beta-lactamase domain protein	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
SRR25158390_k127_4406713_17	478741.JAFS01000001_gene2211	5.129e-74	260.0	COG1225@1|root,COG1225@2|Bacteria,46SWU@74201|Verrucomicrobia,37GJJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158390_k127_4406713_22	1123023.JIAI01000004_gene8250	3.149e-37	159.0	COG0511@1|root,COG0511@2|Bacteria,2GMCA@201174|Actinobacteria,4E2PV@85010|Pseudonocardiales	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_4406713_7	1123320.KB889664_gene987	1.597e-122	400.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158390_k127_4406713_20	1133849.O3I_038160	3.112e-57	211.0	COG2021@1|root,COG2021@2|Bacteria,2IMKC@201174|Actinobacteria,4G03M@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_4406713_23	1313172.YM304_05050	5.675e-37	144.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4CNB7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_4406713_3	1160718.SU9_05371	4.952e-149	487.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_4406713_16	1283299.AUKG01000001_gene1973	1.192e-74	259.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158390_k127_4406713_21	2074.JNYD01000016_gene4210	1.091e-51	201.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4E0NV@85010|Pseudonocardiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158390_k127_4406713_19	1123320.KB889585_gene1873	7.872e-66	237.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158390_k127_4406713_2	1123320.KB889585_gene1872	3.243e-168	537.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4406713_25	926554.KI912673_gene2821	7.415e-24	109.0	2DPBC@1|root,331CT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4406713_13	1123023.JIAI01000003_gene3051	1.673e-78	279.0	COG1090@1|root,COG1090@2|Bacteria,2I3Q5@201174|Actinobacteria,4EEAQ@85010|Pseudonocardiales	201174|Actinobacteria	S	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158390_k127_4406713_18	298653.Franean1_6235	9.966e-74	253.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4EVNB@85013|Frankiales	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158390_k127_4406713_6	1179773.BN6_48180	1.004e-126	414.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4E10Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4406713_0	479435.Kfla_0728	6.037e-227	717.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DU3U@85009|Propionibacteriales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158390_k127_4406713_24	479431.Namu_3712	1.591e-29	126.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4ETDE@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158390_k127_4406713_4	1206729.BAFZ01000049_gene5057	2.421e-145	476.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4FVD0@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_4406713_15	219305.MCAG_05351	2.657e-78	265.0	COG0406@1|root,COG0406@2|Bacteria,2IJ7S@201174|Actinobacteria,4DDQU@85008|Micromonosporales	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158390_k127_4414176_8	1313172.YM304_26000	7.134e-70	255.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_4414176_13	1229780.BN381_400037	7.599e-41	162.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,3UWRN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158390_k127_4414176_10	1229780.BN381_400038	4.252e-58	222.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,3UWZY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158390_k127_4414176_9	1229780.BN381_400039	2.121e-61	243.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,3UWZ5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158390_k127_4414176_5	1229780.BN381_400040	3.363e-103	345.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158390_k127_4414176_1	1313172.YM304_26020	2.779e-252	782.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158390_k127_4414176_12	565045.NOR51B_1489	1.979e-44	170.0	2F1PW@1|root,33UQ6@2|Bacteria,1RHX8@1224|Proteobacteria,1SPAN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4414176_6	1313172.YM304_26040	3.659e-92	309.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4CMY5@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158390_k127_4414176_4	1313172.YM304_26050	1.075e-103	344.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4CMX8@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158390_k127_4414176_17	1313172.YM304_26060	4.928e-18	85.0	2E9C2@1|root,333JS@2|Bacteria,2HGHP@201174|Actinobacteria,4CNEV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158390_k127_4414176_2	1313172.YM304_26070	1.427e-203	644.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CMSZ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pup-ligase protein	dop	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158390_k127_4414176_0	1313172.YM304_26090	3.881e-263	822.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CMRU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Proteasomal ATPase OB/ID domain	arc	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158390_k127_4414176_15	1229780.BN381_410005	2.217e-34	134.0	COG1141@1|root,COG1141@2|Bacteria,2IKKX@201174|Actinobacteria	201174|Actinobacteria	C	ferredoxin	fdxG	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
SRR25158390_k127_4414176_11	1268303.RHODMAR_1324	1.476e-57	215.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4FU76@85025|Nocardiaceae	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158390_k127_4414176_7	1313172.YM304_26120	3.677e-87	310.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CN0Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158390_k127_4414176_3	1313172.YM304_26130	3.133e-134	434.0	COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria	201174|Actinobacteria	D	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158390_k127_4414176_19	1122247.C731_3323	1.378e-14	84.0	COG2104@1|root,COG2104@2|Bacteria,2H07J@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_4414176_18	525909.Afer_0902	1.405e-15	83.0	28R1E@1|root,2ZDG1@2|Bacteria,2HDQB@201174|Actinobacteria,4CNE2@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158390_k127_4414176_14	1869.MB27_31830	2.957e-36	140.0	COG3547@1|root,COG3547@2|Bacteria,2IDDB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3512a	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_4415838_5	700508.D174_16225	1.083e-140	454.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23F6M@1762|Mycobacteriaceae	201174|Actinobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_4415838_30	1120999.JONM01000004_gene3722	7.234e-06	53.0	COG2050@1|root,COG2050@2|Bacteria,1RHP8@1224|Proteobacteria,2VWKH@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_4415838_16	765420.OSCT_1526	9.125e-45	169.0	COG2085@1|root,COG2085@2|Bacteria,2G900@200795|Chloroflexi,37616@32061|Chloroflexia	32061|Chloroflexia	C	NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158390_k127_4415838_12	264732.Moth_0027	3.02e-72	257.0	COG2812@1|root,COG3416@1|root,COG2812@2|Bacteria,COG3416@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,42FGC@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158390_k127_4415838_26	1229780.BN381_150040	7.176e-13	79.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,3UWAK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158390_k127_4415838_25	1052684.PPM_0139	2.858e-14	81.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158390_k127_4415838_7	1449353.JQMQ01000005_gene3194	2.303e-92	306.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,2NE8F@228398|Streptacidiphilus	201174|Actinobacteria	L	RecR protein	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158390_k127_4415838_2	1122939.ATUD01000001_gene199	1.837e-178	566.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4415838_29	1297742.A176_00517	7.405e-07	59.0	COG2172@1|root,COG2172@2|Bacteria,1RKVT@1224|Proteobacteria	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158390_k127_4415838_21	996637.SGM_4246	1.921e-29	127.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158390_k127_4415838_0	1229780.BN381_150129	1.807e-232	742.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,3UX61@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158390_k127_4415838_27	1229780.BN381_150123	1.424e-08	68.0	COG2064@1|root,COG2064@2|Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein F	gspF	-	-	ko:K12510,ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_4415838_32	1122138.AQUZ01000077_gene6422	0.0002472	52.0	COG4965@1|root,COG4965@2|Bacteria,2I8NR@201174|Actinobacteria,4DRXI@85009|Propionibacteriales	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_4415838_6	1380390.JIAT01000010_gene4132	1.397e-98	338.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CR9H@84995|Rubrobacteria	84995|Rubrobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158390_k127_4415838_23	1229780.BN381_150120	3.065e-27	122.0	2FKUI@1|root,34CEY@2|Bacteria,2HCF2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4415838_11	525909.Afer_1925	1.425e-74	259.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CN1K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158390_k127_4415838_9	1229780.BN381_30008	5.897e-91	322.0	COG0038@1|root,COG0038@2|Bacteria	2|Bacteria	P	chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158390_k127_4415838_3	1229780.BN381_100019	6.474e-171	548.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_4415838_18	1380356.JNIK01000011_gene1782	7.819e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_4415838_17	1370121.AUWS01000030_gene2898	7.41e-39	162.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_4415838_20	1229780.BN381_10085	8.234e-32	133.0	COG1011@1|root,COG1011@2|Bacteria,2HP8I@201174|Actinobacteria,3UWYW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158390_k127_4415838_1	1313172.YM304_38270	4.714e-229	722.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CMPV@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158390_k127_4415838_4	1123322.KB904650_gene1803	5.425e-169	568.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158390_k127_4415838_8	1347086.CCBA010000003_gene3907	6.398e-92	319.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus	91061|Bacilli	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158390_k127_4415838_10	479432.Sros_3974	1.653e-76	261.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4EG14@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4415838_19	285535.JOEY01000086_gene7198	4.606e-35	154.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4415838_13	1313172.YM304_41590	1.722e-56	207.0	COG0218@1|root,COG0218@2|Bacteria	2|Bacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158390_k127_4415838_14	103733.JNYO01000042_gene6082	1.337e-55	202.0	arCOG04511@1|root,329Z6@2|Bacteria,2GYB3@201174|Actinobacteria	201174|Actinobacteria	S	Fe2+ transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Iron_transport
SRR25158390_k127_4415838_15	675635.Psed_0672	7.895e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,4EBN0@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4415838_28	743718.Isova_2968	7.152e-08	59.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4F5A8@85017|Promicromonosporaceae	201174|Actinobacteria	L	SMART HNH nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_4433548_2	512565.AMIS_49100	6.409e-89	307.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GJBR@201174|Actinobacteria	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
SRR25158390_k127_4433548_11	1096756.ATKN01000020_gene1606	1.384e-10	66.0	2ETGF@1|root,33CJI@2|Bacteria,2GYV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4433548_0	351607.Acel_0803	4.615e-130	429.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4ES0A@85013|Frankiales	201174|Actinobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	fprD	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158390_k127_4433548_3	1048339.KB913029_gene2692	8.726e-88	308.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4ESFD@85013|Frankiales	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158390_k127_4433548_1	1229780.BN381_420013	1.47e-96	326.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_4433548_7	1173020.Cha6605_5897	2.16e-47	176.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158390_k127_4433548_6	1121019.AUMN01000021_gene1282	7.755e-51	186.0	COG3832@1|root,COG3832@2|Bacteria,2GSCI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_4433548_9	1032480.MLP_45300	1.205e-29	127.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,4DV8G@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_4433548_10	1122182.KB903820_gene60	1.54e-22	106.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4DFNX@85008|Micromonosporales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_4433548_5	446470.Snas_5222	9.968e-55	198.0	2DMC7@1|root,32J0V@2|Bacteria,2I81N@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158390_k127_4433548_8	749927.AMED_0757	1.577e-30	125.0	COG0640@1|root,COG0640@2|Bacteria,2IMCE@201174|Actinobacteria,4EC5P@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_4433548_4	1121272.KB903291_gene3603	1.021e-74	269.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DEE4@85008|Micromonosporales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158390_k127_4436482_0	471852.Tcur_2404	8.394e-180	565.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4EI6I@85012|Streptosporangiales	201174|Actinobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_4436482_3	1078020.KEK_20558	6.455e-94	314.0	COG0778@1|root,COG0778@2|Bacteria,2GM9M@201174|Actinobacteria,235BZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_4436482_2	926550.CLDAP_06320	1.491e-146	473.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_4436482_7	1313172.YM304_36130	3.545e-17	86.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	fldA	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
SRR25158390_k127_4436482_5	68570.DC74_5355	4.86e-39	162.0	COG0715@1|root,COG0715@2|Bacteria,2GNBY@201174|Actinobacteria	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158390_k127_4436482_1	356851.JOAN01000015_gene2551	1.191e-163	528.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4DA7H@85008|Micromonosporales	201174|Actinobacteria	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158390_k127_4436482_6	1869.MB27_30225	6.411e-29	127.0	COG0124@1|root,COG0124@2|Bacteria,2GJXW@201174|Actinobacteria,4D8MZ@85008|Micromonosporales	201174|Actinobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4436482_4	1120934.KB894416_gene4102	1.289e-48	196.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4EB8G@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_4469123_6	1123320.KB889747_gene7184	2.102e-30	134.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_4469123_0	1123320.KB889747_gene7183	8.933e-168	539.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRR25158390_k127_4469123_1	1449353.JQMQ01000005_gene5520	1.567e-145	497.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,2NEQU@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158390_k127_4469123_3	1229780.BN381_780003	7.998e-42	158.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_4469123_2	653045.Strvi_4443	4.3e-104	343.0	COG0262@1|root,COG0262@2|Bacteria,2IR7J@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_4469123_4	1056512.D515_02366	5.596e-39	153.0	COG0662@1|root,COG0662@2|Bacteria,1NCNA@1224|Proteobacteria,1THD1@1236|Gammaproteobacteria,1Y0X5@135623|Vibrionales	135623|Vibrionales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_4469123_5	1120797.KB908270_gene2918	4.859e-31	126.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria,239VE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Death-on-curing protein	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158390_k127_4477635_1	1169152.AXVD01000030_gene4506	1.445e-44	167.0	COG0346@1|root,COG0346@2|Bacteria,2IKRF@201174|Actinobacteria,4G1MW@85025|Nocardiaceae	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4477635_3	405948.SACE_6598	3.522e-37	144.0	COG2764@1|root,COG2764@2|Bacteria,2HS0W@201174|Actinobacteria,4EBSG@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4477635_2	1229203.KI301992_gene1723	2.634e-38	159.0	COG2208@1|root,COG4251@1|root,COG2208@2|Bacteria,COG4251@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,PAS_2,PHY,SpoIIE
SRR25158390_k127_4477635_5	1173026.Glo7428_2420	3.474e-20	104.0	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158390_k127_4477635_4	1906.SFRA_16790	5.507e-35	139.0	COG0789@1|root,COG0789@2|Bacteria,2IQGQ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_4477635_0	1120950.KB892707_gene4643	5.888e-60	214.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNT3@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158390_k127_4513254_19	1463825.JNXC01000016_gene5265	6.046e-33	139.0	COG1309@1|root,COG1309@2|Bacteria,2IEP0@201174|Actinobacteria,4E7C2@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_4513254_0	1313172.YM304_19960	7.726e-318	989.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CMVH@84992|Acidimicrobiia	84992|Acidimicrobiia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158390_k127_4513254_15	1396141.BATP01000057_gene2980	5.101e-59	209.0	COG0503@1|root,COG0503@2|Bacteria,46SV8@74201|Verrucomicrobia,2IUHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158390_k127_4513254_10	1146883.BLASA_2328	4.638e-77	281.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4ERCU@85013|Frankiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158390_k127_4513254_8	1313172.YM304_19930	1.033e-99	347.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CMXX@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
SRR25158390_k127_4513254_20	34007.IT40_21610	1.904e-15	81.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2PXDN@265|Paracoccus	28211|Alphaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158390_k127_4513254_7	1121861.KB899923_gene3419	3.203e-101	359.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2JPNV@204441|Rhodospirillales	204441|Rhodospirillales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158390_k127_4513254_9	1313172.YM304_19900	4.05e-92	329.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4CMRE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158390_k127_4513254_2	1229780.BN381_50110	4.132e-156	498.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,3UWC6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158390_k127_4513254_16	1229780.BN381_50109	3.04e-52	197.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,3UWUJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158390_k127_4513254_17	1229780.BN381_50108	4.552e-47	178.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,3UWKV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158390_k127_4513254_18	1313172.YM304_19850	6.604e-45	176.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,4CN6R@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158390_k127_4513254_6	525909.Afer_1219	3.848e-102	340.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CMY7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158390_k127_4513254_13	1123023.JIAI01000029_gene4439	1.344e-62	221.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4DXHN@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158390_k127_4513254_21	471852.Tcur_3665	6.813e-15	90.0	COG3147@1|root,COG3147@2|Bacteria,2ID4R@201174|Actinobacteria,4EHHH@85012|Streptosporangiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4513254_3	1313172.YM304_19820	1.094e-142	457.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CMSX@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158390_k127_4513254_5	1313172.YM304_19800	4.814e-113	372.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CNA7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158390_k127_4513254_12	1229780.BN381_50097	7.4e-66	231.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,3UWSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158390_k127_4513254_4	1313172.YM304_19780	9.329e-125	411.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CN3N@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158390_k127_4513254_11	1313172.YM304_19760	2.667e-74	260.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4CN56@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158390_k127_4513254_14	1313172.YM304_19750	2.691e-61	218.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CN1P@84992|Acidimicrobiia	84992|Acidimicrobiia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_4513254_1	580327.Tthe_0394	2.422e-189	617.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Translation elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158390_k127_4529665_2	1449353.JQMQ01000005_gene499	1.025e-85	287.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,2NHGV@228398|Streptacidiphilus	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4529665_0	565045.NOR51B_1530	3.873e-163	522.0	COG0620@1|root,COG0620@2|Bacteria,1QJ82@1224|Proteobacteria,1TH64@1236|Gammaproteobacteria,1J9IH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	E COG0620 Methionine synthase II (cobalamin-independent)	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
SRR25158390_k127_4529665_3	935866.JAER01000012_gene3554	3.161e-80	282.0	COG0317@1|root,COG0317@2|Bacteria,2IC8P@201174|Actinobacteria	201174|Actinobacteria	KT	Guanosine polyphosphate pyrophosphohydrolases synthetases	spoT	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158390_k127_4529665_4	58123.JOFJ01000007_gene586	1.421e-34	154.0	COG3087@1|root,COG3087@2|Bacteria,2GNX9@201174|Actinobacteria,4EIUA@85012|Streptosporangiales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4529665_1	1166018.FAES_1040	3.652e-124	409.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,47MCY@768503|Cytophagia	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas
SRR25158390_k127_4529665_5	526225.Gobs_1859	5.385e-24	104.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4ERIG@85013|Frankiales	201174|Actinobacteria	L	PFAM Transposase, Mutator	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR25158390_k127_456471_3	1169161.KB897718_gene3314	9.422e-109	367.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria	201174|Actinobacteria	V	MATE efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158390_k127_456471_0	1313172.YM304_33670	3.016e-259	814.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CMQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158390_k127_456471_4	1125971.ASJB01000043_gene3188	6.264e-61	239.0	COG1215@1|root,COG1215@2|Bacteria,2I3DR@201174|Actinobacteria,4EDPZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_456471_2	1123258.AQXZ01000019_gene2852	3.17e-141	482.0	COG3379@1|root,COG3379@2|Bacteria,2GVVM@201174|Actinobacteria	201174|Actinobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158390_k127_456471_1	1229780.BN381_80039	6.505e-179	568.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,3UWFJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Thiamine pyrophosphate enzyme, central domain	ilvB	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3003c	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_499650_0	103733.JNYO01000026_gene8832	5.148e-144	479.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4E0HP@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158390_k127_499650_2	749414.SBI_01698	8.468e-27	127.0	COG1881@1|root,COG1881@2|Bacteria,2IIR9@201174|Actinobacteria	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158390_k127_499650_3	1120948.KB903218_gene2170	4.192e-23	102.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158390_k127_499650_1	439235.Dalk_5268	3.428e-75	282.0	COG3356@1|root,COG3356@2|Bacteria,1QW1Q@1224|Proteobacteria,43BRP@68525|delta/epsilon subdivisions,2X72J@28221|Deltaproteobacteria,2MMRW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158390_k127_502181_2	1089551.KE386572_gene4278	1.307e-55	214.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_502181_3	1160137.KB907307_gene1742	3.436e-52	201.0	COG0563@1|root,COG0563@2|Bacteria,2IGX9@201174|Actinobacteria,4G25V@85025|Nocardiaceae	201174|Actinobacteria	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_33,SKI
SRR25158390_k127_502181_0	1229780.BN381_100087	6.96e-231	723.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,3UWIX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158390_k127_502181_1	1192034.CAP_5764	2.855e-131	437.0	COG4690@1|root,COG4690@2|Bacteria,1RBRZ@1224|Proteobacteria	1224|Proteobacteria	E	dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
SRR25158390_k127_502181_4	1370121.AUWS01000010_gene5948	2.75e-35	141.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_509185_0	1313172.YM304_18440	3.385e-201	634.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CMPW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribonuclease E/G family	-	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR25158390_k127_509185_9	1229780.BN381_80103	5.515e-33	136.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,3UWVG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158390_k127_509185_10	1203632.HMPREF1300_00991	1.269e-28	127.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,22NIK@1653|Corynebacteriaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158390_k127_509185_1	1229780.BN381_10207	2.111e-151	491.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,3UWET@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158390_k127_509185_4	1313172.YM304_23440	2.064e-106	358.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CMY3@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158390_k127_509185_3	1068980.ARVW01000001_gene5613	1.601e-111	366.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158390_k127_509185_5	33876.JNXY01000026_gene3402	2.409e-99	329.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DB7B@85008|Micromonosporales	201174|Actinobacteria	J	tRNA rRNA methyltransferase	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158390_k127_509185_6	1229780.BN381_10209	5.82e-82	280.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158390_k127_509185_2	861299.J421_3230	4.178e-118	415.0	COG0728@1|root,COG0728@2|Bacteria,1ZTCM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158390_k127_509185_7	1229780.BN381_10211	6.373e-46	175.0	2CIFA@1|root,348QY@2|Bacteria,2H88E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_509185_8	1229780.BN381_20066	4.522e-45	170.0	COG1653@1|root,COG1653@2|Bacteria,2HP0P@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
SRR25158390_k127_510671_6	1123258.AQXZ01000008_gene1318	2.153e-76	264.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4FXY5@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_510671_22	875328.JDM601_3382	1.261e-13	74.0	COG2337@1|root,COG2337@2|Bacteria,2IMGQ@201174|Actinobacteria,23B5D@1762|Mycobacteriaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_510671_9	1150599.MPHLEI_19679	2.982e-56	200.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,238KG@1762|Mycobacteriaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR25158390_k127_510671_12	1313172.YM304_18580	2.739e-48	183.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CN8I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158390_k127_510671_7	1229780.BN381_330013	1.044e-64	224.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,3UWQ3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158390_k127_510671_16	1313172.YM304_18600	3.34e-35	149.0	COG0711@1|root,COG0711@2|Bacteria,2HG9T@201174|Actinobacteria,4CN89@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_510671_19	1229780.BN381_330015	1.525e-28	124.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,3UWUU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158390_k127_510671_20	1313172.YM304_18640	1.306e-20	93.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158390_k127_510671_24	373994.Riv7116_0105	2.801e-12	74.0	COG0416@1|root,COG0416@2|Bacteria,1G1CT@1117|Cyanobacteria,1HJJ9@1161|Nostocales	1117|Cyanobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158390_k127_510671_4	1313172.YM304_18650	4.864e-87	294.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CMRM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158390_k127_510671_14	1313172.YM304_18660	6.88e-37	141.0	COG0236@1|root,COG0236@2|Bacteria,2HG9V@201174|Actinobacteria,4CN8D@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158390_k127_510671_8	1313172.YM304_18670	5.79e-63	224.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CN7Y@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158390_k127_510671_10	1229780.BN381_330022	6.808e-54	199.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158390_k127_510671_0	1229780.BN381_330023	0.0	1061.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,3UWCX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158390_k127_510671_2	1313172.YM304_18700	1.559e-107	378.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CMY6@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54
SRR25158390_k127_510671_1	1313172.YM304_18720	1.599e-187	597.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CMPN@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158390_k127_510671_18	1229780.BN381_330035	2.045e-31	129.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,3UWU1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158390_k127_510671_21	1229780.BN381_330036	2.181e-14	77.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	CP_0960	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158390_k127_510671_13	1229780.BN381_330037	2.725e-41	165.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,3UWUH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158390_k127_510671_3	1229780.BN381_330038	9.918e-101	333.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,3UWGW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158390_k127_510671_11	28042.GU90_17700	1.666e-49	181.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158390_k127_510671_15	43354.JOIJ01000004_gene3517	3.223e-36	139.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4E3KG@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158390_k127_510671_17	1229780.BN381_330042	2.951e-32	129.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,3UWWQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Uncharacterised protein family UPF0102	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158390_k127_510671_5	1313172.YM304_18790	6.92e-80	274.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4CNAF@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158390_k127_510673_4	706587.Desti_3549	8.43e-66	241.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MQH9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_510673_3	479432.Sros_2090	1.099e-102	358.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_510673_2	43759.JNWK01000016_gene312	1.813e-146	510.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_510673_1	1229780.BN381_150119	1.545e-162	546.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158390_k127_510673_0	1313172.YM304_02620	1.646e-187	603.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CMW8@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_521860_8	1121877.JQKF01000002_gene1753	0.0001945	46.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CNKC@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158390_k127_521860_2	378806.STAUR_7628	2.532e-59	222.0	COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,42W6J@68525|delta/epsilon subdivisions,2WSAJ@28221|Deltaproteobacteria,2YZEF@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_521860_4	525909.Afer_0497	3.541e-41	168.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CNH1@84992|Acidimicrobiia	84992|Acidimicrobiia	G	ROK family	-	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158390_k127_521860_0	485913.Krac_12393	1.389e-214	691.0	COG3387@1|root,COG3387@2|Bacteria,2G7S0@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG3387 Glucoamylase and related glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158390_k127_521860_1	1906.SFRA_03245	1.519e-62	223.0	COG1595@1|root,COG1595@2|Bacteria,2GJG2@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_521860_6	67267.JNXT01000017_gene7215	7.335e-18	91.0	291EA@1|root,2ZP15@2|Bacteria,2ITEP@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_521860_3	557599.MKAN_01345	4.525e-50	197.0	COG0062@1|root,COG0062@2|Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158390_k127_521860_5	1146883.BLASA_1739	1.272e-19	94.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_521860_7	1146883.BLASA_1739	1.025e-11	78.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_526202_3	1313172.YM304_19310	1.729e-73	273.0	COG1305@1|root,COG1305@2|Bacteria,2HH1I@201174|Actinobacteria,4CP1R@84992|Acidimicrobiia	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158390_k127_526202_6	1121877.JQKF01000004_gene1087	1.3e-21	101.0	2ERJT@1|root,33J59@2|Bacteria,2HGGQ@201174|Actinobacteria,4CNDW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR25158390_k127_526202_0	1313172.YM304_19290	8.185e-113	379.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CNR5@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158390_k127_526202_5	1229780.BN381_140026	4.458e-40	156.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	MA20_41050	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158390_k127_526202_4	1121877.JQKF01000004_gene1089	1.393e-49	197.0	COG2120@1|root,COG2120@2|Bacteria,2HF8J@201174|Actinobacteria,4CNQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158390_k127_526202_1	1121877.JQKF01000004_gene1090	1.401e-79	282.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4CNM1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158390_k127_526202_2	351607.Acel_1405	2.125e-75	267.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4ESCZ@85013|Frankiales	201174|Actinobacteria	G	Inositol monophosphatase	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158390_k127_526202_7	1313172.YM304_19260	7.9e-20	89.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_530551_4	1313172.YM304_00110	1.602e-36	147.0	COG1748@1|root,COG1748@2|Bacteria,2H8X8@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_530551_7	1229780.BN381_100174	3.35e-06	59.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR25158390_k127_530551_8	1219049.SP5_034_01430	0.0009444	49.0	COG1511@1|root,COG1511@2|Bacteria	2|Bacteria	Q	domain protein	ebh	-	-	ko:K12056	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	DUF1542,FIVAR,GA,YSIRK_signal
SRR25158390_k127_530551_0	1313172.YM304_00070	0.0	1067.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CMSQ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA Topoisomerase IV	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158390_k127_530551_1	1121877.JQKF01000017_gene188	1.021e-280	875.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CMQZ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TopoisomeraseII	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158390_k127_530551_6	1050202.KB913024_gene3440	3.963e-07	57.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4097V@622450|Actinopolysporales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158390_k127_530551_3	469371.Tbis_0004	2.446e-77	276.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4DYPY@85010|Pseudonocardiales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158390_k127_530551_2	1229780.BN381_100168	3.281e-133	434.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,3UWB4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158390_k127_53459_4	1313172.YM304_36470	7.28e-92	320.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_53459_7	208444.JNYY01000006_gene6874	1.415e-44	182.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4E52D@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_53459_5	1313172.YM304_13340	4.561e-50	185.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158390_k127_53459_2	1229780.BN381_80149	4.222e-144	470.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,3UW9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158390_k127_53459_6	1313172.YM304_13050	4.948e-45	168.0	2F7CY@1|root,33ZTZ@2|Bacteria,2H76P@201174|Actinobacteria,4CNCM@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_53459_0	1229780.BN381_80143	2.004e-234	738.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,3UWEK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	LeuA allosteric (dimerisation) domain	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158390_k127_53459_1	1313172.YM304_13000	1.375e-152	497.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CMVG@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158390_k127_53459_3	1121877.JQKF01000003_gene1452	5.068e-128	417.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CMRK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158390_k127_56066_12	886293.Sinac_3574	7.664e-67	232.0	COG1902@1|root,COG1902@2|Bacteria,2IXBM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158390_k127_56066_6	981369.JQMJ01000004_gene5429	1.406e-87	308.0	COG0111@1|root,COG0111@2|Bacteria,2GKN6@201174|Actinobacteria,2NFMT@228398|Streptacidiphilus	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_56066_7	926550.CLDAP_16050	2.878e-87	308.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_56066_13	1128421.JAGA01000001_gene2102	2.321e-64	232.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
SRR25158390_k127_56066_21	457429.ABJI02000543_gene1607	5.702e-22	99.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_56066_19	1403313.AXBR01000024_gene4766	3.239e-33	144.0	COG1680@1|root,COG1680@2|Bacteria,1VSBT@1239|Firmicutes,4HV12@91061|Bacilli,1ZIC9@1386|Bacillus	91061|Bacilli	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158390_k127_56066_2	350058.Mvan_5928	1.202e-173	587.0	COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRR25158390_k127_56066_15	1122138.AQUZ01000019_gene8182	1.19e-46	185.0	COG1595@1|root,COG1595@2|Bacteria,2H45C@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_56066_23	1122138.AQUZ01000019_gene8183	9.164e-15	82.0	2DGEZ@1|root,2ZVQ5@2|Bacteria,2GYKS@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_56066_10	1214101.BN159_4299	4.828e-79	280.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158390_k127_56066_5	1214101.BN159_4302	1.19e-102	340.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158390_k127_56066_20	1380390.JIAT01000009_gene842	2.273e-27	115.0	COG2044@1|root,COG2044@2|Bacteria,2HRHX@201174|Actinobacteria,4CTI1@84995|Rubrobacteria	84995|Rubrobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158390_k127_56066_8	485913.Krac_2036	3.849e-86	296.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_56066_4	1122138.AQUZ01000019_gene8137	2.132e-129	429.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4DPGY@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_56066_9	883080.HMPREF9697_00919	5.529e-86	299.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,2TTIW@28211|Alphaproteobacteria,3JWT4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Formate/nitrite transporter	-	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
SRR25158390_k127_56066_0	557599.MKAN_13600	2.953e-232	730.0	COG0500@1|root,COG1964@1|root,COG1964@2|Bacteria,COG2226@2|Bacteria,2I9RQ@201174|Actinobacteria,2336U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_11,Radical_SAM
SRR25158390_k127_56066_11	675635.Psed_1269	1.258e-67	257.0	COG0500@1|root,COG2226@2|Bacteria,2I5YW@201174|Actinobacteria,4E881@85010|Pseudonocardiales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_56066_3	1146883.BLASA_1348	5.188e-131	433.0	COG2128@1|root,COG2128@2|Bacteria,2IEYG@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158390_k127_56066_18	1122138.AQUZ01000019_gene8124	1.208e-36	154.0	COG0500@1|root,COG2226@2|Bacteria,2IBQJ@201174|Actinobacteria,4DR85@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_56066_17	557599.MKAN_09120	4.678e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,2HSCT@201174|Actinobacteria,23BG8@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_56066_16	1146883.BLASA_0805	2.666e-46	178.0	2F7BB@1|root,342EN@2|Bacteria	2|Bacteria	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRR25158390_k127_56066_14	1206101.AZXC01000016_gene3444	1.594e-62	220.0	COG1595@1|root,COG1595@2|Bacteria,2GJG2@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_56066_22	100226.SCO3449	1.632e-19	99.0	291EA@1|root,2ZP15@2|Bacteria,2ITEP@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_56066_25	1082931.KKY_1808	8.305e-07	54.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,3N6UN@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	cytochrome c biogenesis protein	MA20_17170	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158390_k127_56066_24	1906.SFRA_03250	1.849e-08	65.0	2AYNY@1|root,31QTF@2|Bacteria,2ISMX@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_56066_1	67373.JOBF01000002_gene1336	5.323e-178	572.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_576942_4	1386089.N865_07150	3.124e-67	232.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4FH86@85021|Intrasporangiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158390_k127_576942_3	1380390.JIAT01000009_gene1027	1.022e-76	267.0	COG2207@1|root,COG2207@2|Bacteria,2H1NG@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_576942_1	68219.JNXI01000021_gene3666	3.79e-113	376.0	COG3268@1|root,COG3268@2|Bacteria,2GMKU@201174|Actinobacteria	201174|Actinobacteria	S	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158390_k127_576942_2	1193181.BN10_690004	3.283e-111	365.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FFNS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_576942_5	1120950.KB892709_gene4139	1.883e-49	182.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4DRYH@85009|Propionibacteriales	201174|Actinobacteria	S	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_576942_0	219305.MCAG_03092	8.588e-141	451.0	COG2334@1|root,COG2334@2|Bacteria,2HZ9Z@201174|Actinobacteria,4D9TY@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_576942_7	1463857.JOFZ01000008_gene374	2.483e-16	91.0	COG4122@1|root,COG4122@2|Bacteria,2GJCJ@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158390_k127_576942_6	457429.ABJI02000069_gene5147	4.442e-32	128.0	COG4122@1|root,COG4122@2|Bacteria,2GJCJ@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158390_k127_579976_2	1206730.BAGA01000179_gene2867	1.3e-154	503.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,4G9JQ@85025|Nocardiaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158390_k127_579976_9	1123320.KB889687_gene894	1.026e-20	100.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158390_k127_579976_1	1229780.BN381_10027	2.006e-177	583.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,3UWBD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158390_k127_579976_3	1229780.BN381_10028	3.174e-111	376.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,3UWGE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158390_k127_579976_5	1229780.BN381_10042	8.603e-63	230.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,3UWN7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158390_k127_579976_10	1449068.JMLQ01000015_gene4166	2.09e-15	87.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4G336@85025|Nocardiaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158390_k127_579976_11	649743.HMPREF0972_02528	5.57e-10	70.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4D5KI@85005|Actinomycetales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158390_k127_579976_6	1313172.YM304_10630	1.465e-47	189.0	COG0712@1|root,COG0712@2|Bacteria,2HGFG@201174|Actinobacteria,4CND3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158390_k127_579976_0	1313172.YM304_10640	1.527e-240	754.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CMTI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158390_k127_579976_4	1229780.BN381_10048	7.923e-95	321.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,3UWAU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158390_k127_579976_7	525909.Afer_1795	5.619e-42	157.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CMWB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158390_k127_59777_5	1193181.BN10_680074	2.118e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4FGF5@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_59777_2	543632.JOJL01000023_gene1731	9.557e-100	332.0	COG1073@1|root,COG1073@2|Bacteria,2I2SC@201174|Actinobacteria,4D9P3@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_59777_0	1380390.JIAT01000010_gene3898	0.0	1067.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4CR4U@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_59777_3	356851.JOAN01000029_gene4970	4.097e-98	329.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4DD0R@85008|Micromonosporales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158390_k127_59777_1	1353531.AZNX01000008_gene715	2.705e-124	400.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2TTHB@28211|Alphaproteobacteria,4B9T6@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	MA20_01595	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158390_k127_59777_4	1313172.YM304_04330	5.83e-46	168.0	COG4270@1|root,COG4270@2|Bacteria,2IKKP@201174|Actinobacteria	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158390_k127_610913_3	298655.KI912266_gene6120	8.899e-75	257.0	2F48B@1|root,33WZ6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRR25158390_k127_610913_4	83332.Rv2829c	1.278e-55	201.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_610913_5	83332.Rv2830c	8.282e-29	121.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158390_k127_610913_1	298655.KI912266_gene5423	3.541e-200	630.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU00@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_610913_0	298654.FraEuI1c_4314	5.898e-265	825.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_610913_2	298655.KI912266_gene6070	4.253e-143	458.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EU6F@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_656292_10	103733.JNYO01000013_gene4346	4.2e-35	136.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4E3MA@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM redox-sensitive transcriptional activator SoxR	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158390_k127_656292_8	1206725.BAFU01000070_gene6214	1.486e-40	157.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4G30K@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_656292_12	1227349.C170_11675	3.759e-08	64.0	COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,26SV3@186822|Paenibacillaceae	91061|Bacilli	I	Acyltransferase	oatA	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158390_k127_656292_9	1313172.YM304_31100	1.007e-36	154.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158390_k127_656292_7	935839.JAGJ01000018_gene2314	9.929e-52	197.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4F392@85017|Promicromonosporaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158390_k127_656292_6	644283.Micau_2764	2.116e-57	214.0	COG0500@1|root,COG2226@2|Bacteria,2I36Q@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_656292_11	1123320.KB889627_gene7913	3.141e-08	64.0	2BEUS@1|root,328KD@2|Bacteria,2HEDT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_656292_4	436229.JOEH01000010_gene5144	1.37e-82	294.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,2NF0X@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_656292_2	351607.Acel_0516	4.21e-99	350.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
SRR25158390_k127_656292_5	471852.Tcur_1124	2.963e-63	224.0	COG0784@1|root,COG0784@2|Bacteria,2IFH8@201174|Actinobacteria,4ER7Q@85012|Streptosporangiales	201174|Actinobacteria	T	cheY-homologous receiver domain	rcp1	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
SRR25158390_k127_656292_1	298655.KI912266_gene1716	2.615e-113	386.0	COG4251@1|root,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,4EURC@85013|Frankiales	201174|Actinobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
SRR25158390_k127_656292_3	1283299.AUKG01000001_gene1843	3.384e-84	314.0	COG2208@1|root,COG2208@2|Bacteria,2GNAF@201174|Actinobacteria,4CR74@84995|Rubrobacteria	84995|Rubrobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
SRR25158390_k127_656292_0	391037.Sare_4398	5.66e-123	417.0	COG1409@1|root,COG1409@2|Bacteria,2GP1M@201174|Actinobacteria,4DBV7@85008|Micromonosporales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158390_k127_656672_5	1121926.AXWO01000002_gene1546	3.667e-16	78.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4EY5Q@85014|Glycomycetales	201174|Actinobacteria	J	Elongation factor Tu C-terminal domain	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158390_k127_656672_1	1348657.M622_14015	8.388e-100	332.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2VIN9@28216|Betaproteobacteria,2KUVW@206389|Rhodocyclales	206389|Rhodocyclales	M	UDP-glucose 4-epimerase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158390_k127_656672_4	1305735.JAFT01000005_gene1589	1.256e-25	123.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2PCB1@252301|Oceanicola	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158390_k127_656672_3	290399.Arth_0934	3.603e-35	141.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158390_k127_656672_2	1313172.YM304_08170	7.763e-49	175.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4CN6W@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158390_k127_656672_0	47763.JNZA01000009_gene5544	7.597e-139	450.0	COG0667@1|root,COG0667@2|Bacteria,2H2ID@201174|Actinobacteria	201174|Actinobacteria	C	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_656672_6	1121877.JQKF01000009_gene548	5.475e-06	57.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CMZP@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158390_k127_666221_12	426117.M446_1050	1.877e-20	94.0	COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VB4S@28211|Alphaproteobacteria,1JT96@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	2-keto-4-pentenoate hydratase	-	-	4.1.1.77	ko:K01617	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R02602,R05374	RC00751,RC02672	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_666221_8	313589.JNB_05959	1.031e-61	216.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria,4FJ1F@85021|Intrasporangiaceae	201174|Actinobacteria	P	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_666221_1	1128421.JAGA01000001_gene2297	8.125e-95	317.0	COG0262@1|root,COG0262@2|Bacteria,2NRYY@2323|unclassified Bacteria	2|Bacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_666221_6	1121272.KB903249_gene1983	1.091e-71	255.0	COG0640@1|root,COG0640@2|Bacteria,2GPH2@201174|Actinobacteria,4D8GW@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_666221_13	1380390.JIAT01000001_gene5032	7.563e-13	80.0	COG0640@1|root,COG0640@2|Bacteria,2GPH2@201174|Actinobacteria,4CQUR@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_666221_4	1206743.BAGM01000095_gene2163	7.336e-76	257.0	2C3KP@1|root,2Z802@2|Bacteria,2IFTZ@201174|Actinobacteria,4G0H7@85025|Nocardiaceae	201174|Actinobacteria	S	phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_666221_11	1306174.JODP01000027_gene130	5.561e-32	127.0	2CFVG@1|root,3346Y@2|Bacteria,2GRCI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158390_k127_666221_3	1150599.MPHLEI_03608	1.552e-76	262.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,23F1N@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158390_k127_666221_14	1206726.BAFV01000038_gene2522	8.023e-10	65.0	COG1813@1|root,COG1813@2|Bacteria,2GSRE@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158390_k127_666221_9	263358.VAB18032_24355	1.164e-53	213.0	COG4907@1|root,COG4907@2|Bacteria,2IBZ3@201174|Actinobacteria,4DBRQ@85008|Micromonosporales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158390_k127_666221_7	1229780.BN381_70015	5.068e-68	241.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,3UWPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158390_k127_666221_10	1229780.BN381_70016	1.986e-33	144.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,3UWWG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Forkhead associated domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158390_k127_666221_2	1229780.BN381_70017	1.219e-77	278.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,3UWNU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158390_k127_666221_0	1313172.YM304_02140	1.71e-138	473.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CMWK@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158390_k127_666221_5	1229780.BN381_70019	1.211e-74	262.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,3UW84@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158390_k127_670154_2	326424.FRAAL3377	5.658e-117	385.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_670154_0	1120949.KB903295_gene2218	5.741e-171	548.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158390_k127_670154_3	1229780.BN381_410016	2.482e-97	326.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,3UWQF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158390_k127_670154_4	67356.KL575589_gene654	6.626e-47	178.0	COG0454@1|root,COG0456@2|Bacteria,2IJC7@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_670154_5	446471.Xcel_2297	1.29e-31	132.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4F5Q5@85017|Promicromonosporaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	xynD	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Polysacc_deac_1
SRR25158390_k127_670154_1	103733.JNYO01000012_gene2781	5.744e-170	551.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DXPV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158390_k127_684054_4	1313172.YM304_07520	1.827e-47	180.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4CMSG@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mg-chelatase subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRR25158390_k127_684054_1	65497.JODV01000031_gene1303	1.959e-233	757.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E15N@85010|Pseudonocardiales	201174|Actinobacteria	P	E1-E2 ATPase	ctpE	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158390_k127_684054_2	1313172.YM304_07510	1.288e-222	712.0	COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria	201174|Actinobacteria	G	beta-mannosidase	csxA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575	3.2.1.165,3.2.1.25	ko:K01192,ko:K15855	ko00511,ko00520,ko01100,ko04142,map00511,map00520,map01100,map04142	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158390_k127_684054_3	1313172.YM304_07470	2.053e-77	270.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158390_k127_684054_0	1128421.JAGA01000003_gene2923	3.104e-309	972.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158390_k127_684054_5	106370.Francci3_3467	3.659e-12	68.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4EUI7@85013|Frankiales	201174|Actinobacteria	C	4Fe-4S binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
SRR25158390_k127_685481_5	1313172.YM304_33140	1.207e-115	387.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CN31@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
SRR25158390_k127_685481_9	706587.Desti_3549	9.097e-83	304.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MQH9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_685481_0	66429.JOFL01000004_gene3581	4e-323	1024.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158390_k127_685481_4	1033730.CAHG01000004_gene70	3.87e-132	435.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4DNF7@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158390_k127_685481_17	675635.Psed_5845	2.989e-33	146.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria,4E3G1@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sig10	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_685481_18	1146883.BLASA_1070	6.102e-23	108.0	COG5660@1|root,COG5660@2|Bacteria,2IHDZ@201174|Actinobacteria,4ET94@85013|Frankiales	201174|Actinobacteria	S	Putative zinc-finger	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_685481_7	479433.Caci_3973	2.726e-84	302.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158390_k127_685481_12	1169161.KB897718_gene3402	9.14e-56	203.0	COG4549@1|root,COG4549@2|Bacteria,2GN9H@201174|Actinobacteria	201174|Actinobacteria	S	nuclear export factor GLE1	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF1775
SRR25158390_k127_685481_11	298655.KI912267_gene7430	2.234e-59	219.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4ESMU@85013|Frankiales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158390_k127_685481_1	1435356.Y013_04375	3.622e-228	730.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4FV1E@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158390_k127_685481_2	1229780.BN381_170003	8.901e-180	575.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,3UWCW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Cytochrome b/b6/petB	qcrB	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158390_k127_685481_8	1229780.BN381_170002	1.561e-83	292.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,3UWCF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158390_k127_685481_13	298653.Franean1_1810	1.183e-55	204.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4ESET@85013|Frankiales	201174|Actinobacteria	C	cytochrome C	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158390_k127_685481_16	525909.Afer_1828	3.783e-46	177.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CNAV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158390_k127_685481_14	28444.JODQ01000001_gene2410	3.229e-55	206.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4EGUX@85012|Streptosporangiales	201174|Actinobacteria	P	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	copD	GO:0008150,GO:0040007	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158390_k127_685481_10	1229780.BN381_20103	1.032e-60	222.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,3UWQE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158390_k127_685481_15	1313172.YM304_33100	1.05e-46	176.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CNB1@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	rplY	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158390_k127_685481_3	1229780.BN381_20100	8.94e-137	442.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,3UW77@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158390_k127_685481_6	351607.Acel_1947	2.075e-85	294.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4ERCR@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158390_k127_688173_5	749927.AMED_5168	4.096e-60	221.0	COG0443@1|root,COG0443@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
SRR25158390_k127_688173_8	1449976.KALB_1912	2.321e-18	94.0	COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GM57@201174|Actinobacteria	201174|Actinobacteria	T	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Sigma70_r2
SRR25158390_k127_688173_1	1123024.AUII01000029_gene4057	1.588e-154	510.0	COG0699@1|root,COG0699@2|Bacteria,2GNGP@201174|Actinobacteria,4DYV2@85010|Pseudonocardiales	201174|Actinobacteria	S	Dynamin family	iniA	GO:0003674,GO:0005215,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015562,GO:0016020,GO:0022857,GO:0030312,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_688173_0	1123023.JIAI01000005_gene655	4.117e-155	515.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria,4DYHH@85010|Pseudonocardiales	201174|Actinobacteria	T	GTPases (dynamin-related)	iniC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_688173_7	266117.Rxyl_0591	6.704e-40	171.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158390_k127_688173_2	1123023.JIAI01000005_gene654	6.014e-104	377.0	COG2197@1|root,COG2197@2|Bacteria,2GNUY@201174|Actinobacteria,4DYXQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_688173_3	1123024.AUII01000021_gene12	1.174e-102	342.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_688173_6	469383.Cwoe_3822	1.058e-55	202.0	COG2128@1|root,COG2128@2|Bacteria,2IFER@201174|Actinobacteria,4CU3Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_688173_9	227882.SAV_4571	0.0001938	48.0	COG2227@1|root,COG2227@2|Bacteria,2GJAQ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158390_k127_688173_4	405948.SACE_6563	3.89e-72	249.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4E3VZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_691026_3	1313172.YM304_04180	1.034e-18	89.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CMUB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein synonym NADH dehydrogenase I subunit M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_691026_0	1229780.BN381_160014	1.942e-154	503.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,3UWFY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_691026_5	1429046.RR21198_2798	1.67e-08	68.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4FX8K@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_691026_2	1229780.BN381_160023	1.999e-47	173.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,3UXDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158390_k127_691026_1	1313172.YM304_35640	3.146e-87	290.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CMXA@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158390_k127_691026_4	1229780.BN381_160025	8.607e-18	94.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,3UWY9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158390_k127_733123_2	1122138.AQUZ01000002_gene2100	2.71e-156	500.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DQ5C@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158390_k127_733123_8	1229780.BN381_640025	1.408e-71	262.0	COG2856@1|root,COG2856@2|Bacteria,2GPBB@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_733123_3	1229780.BN381_290057	1.527e-97	328.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,3UXH6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_733123_15	31234.CRE25445	5.242e-10	70.0	COG5083@1|root,KOG3668@2759|Eukaryota,39RNR@33154|Opisthokonta,3BB03@33208|Metazoa,3CWZR@33213|Bilateria,40B6N@6231|Nematoda,1KV9G@119089|Chromadorea,40XZU@6236|Rhabditida	33208|Metazoa	IT	LNS2	PITPNM2	GO:0003008,GO:0003674,GO:0003824,GO:0005102,GO:0005215,GO:0005319,GO:0005388,GO:0005488,GO:0005509,GO:0005515,GO:0005543,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005790,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0005929,GO:0006629,GO:0006644,GO:0006650,GO:0006661,GO:0006793,GO:0006796,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006820,GO:0006869,GO:0007154,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007600,GO:0007602,GO:0007603,GO:0007606,GO:0007608,GO:0008150,GO:0008152,GO:0008277,GO:0008289,GO:0008324,GO:0008525,GO:0008526,GO:0008610,GO:0008654,GO:0009058,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0010876,GO:0012505,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015630,GO:0015662,GO:0015711,GO:0015748,GO:0015914,GO:0016020,GO:0016021,GO:0016028,GO:0016029,GO:0016056,GO:0016059,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019637,GO:0019829,GO:0019899,GO:0019900,GO:0019901,GO:0022400,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0023051,GO:0023052,GO:0030001,GO:0030971,GO:0031210,GO:0031224,GO:0031226,GO:0031984,GO:0032101,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0034220,GO:0035091,GO:0035556,GO:0035770,GO:0035869,GO:0036464,GO:0042623,GO:0042625,GO:0042626,GO:0042995,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044432,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045017,GO:0045202,GO:0046474,GO:0046486,GO:0046488,GO:0046872,GO:0046873,GO:0048015,GO:0048017,GO:0048513,GO:0048583,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050877,GO:0050896,GO:0050997,GO:0051179,GO:0051234,GO:0051606,GO:0051716,GO:0055085,GO:0060322,GO:0065007,GO:0070300,GO:0070405,GO:0070588,GO:0070838,GO:0071214,GO:0071478,GO:0071482,GO:0071702,GO:0071704,GO:0071781,GO:0071944,GO:0072511,GO:0090407,GO:0090662,GO:0097425,GO:0098655,GO:0098660,GO:0098662,GO:0098827,GO:0099131,GO:0099132,GO:0104004,GO:0120025,GO:0120038,GO:0120082,GO:1901576,GO:1990050,GO:1990782,GO:1990904	-	-	-	-	-	-	-	-	-	-	DDHD,IP_trans
SRR25158390_k127_733123_0	1449355.JQNR01000005_gene4008	1.925e-269	837.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,2GK6D@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fum	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
SRR25158390_k127_733123_1	526225.Gobs_1000	1.115e-196	622.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4ERVS@85013|Frankiales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158390_k127_733123_9	1229780.BN381_310080	1.85e-50	186.0	2FJ53@1|root,34AVA@2|Bacteria,2H8CM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_733123_14	1313172.YM304_13980	1.871e-19	98.0	COG1184@1|root,COG1184@2|Bacteria,2H70W@201174|Actinobacteria	201174|Actinobacteria	J	Initiation factor 2 subunit family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_733123_10	1123320.KB889700_gene9200	1.264e-42	170.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_733123_5	479434.Sthe_2697	7.731e-78	268.0	COG1656@1|root,COG1977@1|root,COG1656@2|Bacteria,COG1977@2|Bacteria,2G6GZ@200795|Chloroflexi,27Y8I@189775|Thermomicrobia	189775|Thermomicrobia	H	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
SRR25158390_k127_733123_11	469383.Cwoe_3092	1.618e-37	151.0	COG3801@1|root,COG3801@2|Bacteria,2HRJB@201174|Actinobacteria,4CTK6@84995|Rubrobacteria	84995|Rubrobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_733123_13	1206739.BAGJ01000027_gene1820	8.426e-21	103.0	COG3170@1|root,COG3170@2|Bacteria,2ICMF@201174|Actinobacteria,4G99M@85025|Nocardiaceae	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_733123_6	1121877.JQKF01000003_gene1502	9.827e-77	263.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4CN01@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_733123_4	1211815.CBYP010000024_gene1507	1.337e-95	330.0	COG4805@1|root,COG4805@2|Bacteria,2GJQT@201174|Actinobacteria,4ETWD@85013|Frankiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_733123_16	1172188.KB911820_gene2680	1.693e-05	57.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4FIWM@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_733123_12	547163.BN979_00229	1.042e-35	149.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_733123_7	1313172.YM304_14270	1.507e-74	254.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CNND@84992|Acidimicrobiia	84992|Acidimicrobiia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158390_k127_734158_6	1150599.MPHLEI_03733	1.377e-24	103.0	COG1545@1|root,COG1545@2|Bacteria,2IH6P@201174|Actinobacteria,23998@1762|Mycobacteriaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_734158_0	1150599.MPHLEI_03738	3.532e-215	676.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,234II@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	ltp1_1	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_734158_2	298655.KI912266_gene2702	1.257e-70	244.0	COG1309@1|root,COG1309@2|Bacteria,2GMJ2@201174|Actinobacteria	201174|Actinobacteria	K	Regulatory protein tetr	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158390_k127_734158_5	469383.Cwoe_3837	1.431e-57	209.0	COG1024@1|root,COG1024@2|Bacteria,2I8WN@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA3	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_734158_3	106370.Francci3_2396	9.556e-65	232.0	COG3651@1|root,COG3651@2|Bacteria,2IHNI@201174|Actinobacteria,4EVHX@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
SRR25158390_k127_734158_4	330084.JNYZ01000029_gene137	8.879e-62	219.0	COG2128@1|root,COG2128@2|Bacteria,2IAT6@201174|Actinobacteria,4EEYQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_734158_1	1041522.MCOL_V220266	1.144e-85	292.0	COG1028@1|root,COG1028@2|Bacteria,2IGF6@201174|Actinobacteria,23EVI@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_766697_1	1313172.YM304_37870	2.102e-93	321.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158390_k127_766697_2	452652.KSE_33640	1.355e-86	295.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,2M0T9@2063|Kitasatospora	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158390_k127_766697_3	1122947.FR7_3131	3.109e-33	143.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4H4P0@909932|Negativicutes	909932|Negativicutes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158390_k127_766697_0	1313172.YM304_37850	4.297e-106	364.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CN61@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158390_k127_766697_4	1229780.BN381_60042	4.474e-31	128.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,3UWP6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158390_k127_803410_9	1229780.BN381_170028	3.668e-31	137.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_803410_6	1463917.JODC01000042_gene2575	2.16e-48	189.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_803410_11	1313172.YM304_41020	8.137e-09	60.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_803410_7	1246448.ANAZ01000025_gene3573	9.757e-40	154.0	COG0645@1|root,COG0645@2|Bacteria,2IKMM@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158390_k127_803410_5	196162.Noca_4640	2.362e-54	199.0	COG1388@1|root,COG1388@2|Bacteria,2IKMC@201174|Actinobacteria	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_803410_2	1048339.KB913029_gene2693	1.553e-66	235.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4ESVJ@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_803410_4	298654.FraEuI1c_4287	8.748e-56	210.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158390_k127_803410_1	298654.FraEuI1c_4286	3.578e-80	279.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_803410_0	105420.BBPO01000011_gene1963	2.761e-86	298.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NHNG@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_803410_8	1075090.GOAMR_64_00060	2.078e-39	167.0	COG0842@1|root,COG0842@2|Bacteria,2H2PR@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_803410_3	1463934.JOCF01000005_gene1425	6.252e-66	231.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158390_k127_803410_10	590998.Celf_1304	1.348e-12	67.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158390_k127_816575_9	1313172.YM304_29050	1.968e-89	300.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CNTU@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158390_k127_816575_11	1313172.YM304_28580	1.627e-76	273.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Polysacc_synt,Polysacc_synt_3
SRR25158390_k127_816575_1	525909.Afer_0728	8.948e-184	582.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
SRR25158390_k127_816575_15	1283283.ATXA01000003_gene1604	1.907e-67	238.0	COG2227@1|root,COG2227@2|Bacteria,2I54M@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158390_k127_816575_24	1254432.SCE1572_15625	2.053e-25	121.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	ydgD	-	-	ko:K04775	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
SRR25158390_k127_816575_22	1227349.C170_17687	8.071e-28	128.0	COG0584@1|root,COG0584@2|Bacteria,1V6FX@1239|Firmicutes,4HWQD@91061|Bacilli,26TWI@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_816575_14	369723.Strop_2135	1.082e-71	267.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_816575_18	1120936.KB907208_gene647	2.044e-62	229.0	COG0438@1|root,COG0438@2|Bacteria,2GX8V@201174|Actinobacteria,4EG9S@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_816575_19	266117.Rxyl_2683	3.708e-55	216.0	COG4424@1|root,COG4424@2|Bacteria,2HETZ@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR25158390_k127_816575_25	517722.AEUE01000004_gene913	1.397e-15	88.0	2ECWR@1|root,336TY@2|Bacteria,1NAQG@1224|Proteobacteria,2UYQJ@28211|Alphaproteobacteria,2KBJZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_816575_13	263358.VAB18032_23365	9.804e-76	287.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_816575_7	298655.KI912266_gene711	7.068e-98	351.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158390_k127_816575_4	1380347.JNII01000007_gene385	1.57e-117	392.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4ESAJ@85013|Frankiales	201174|Actinobacteria	GM	PFAM ABC transporter related	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158390_k127_816575_16	1121372.AULK01000002_gene857	1.114e-64	233.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4FMEB@85023|Microbacteriaceae	201174|Actinobacteria	GM	ABC-2 type transporter	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_816575_10	298653.Franean1_5892	5.583e-81	289.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ET5X@85013|Frankiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158390_k127_816575_8	326424.FRAAL1236	2.392e-94	336.0	COG0438@1|root,COG0438@2|Bacteria,2IJ4J@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_816575_3	469383.Cwoe_3710	5.663e-135	439.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_816575_21	42256.RradSPS_1176	8.206e-36	158.0	COG0463@1|root,COG0463@2|Bacteria,2IB0Y@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
SRR25158390_k127_816575_12	595460.RRSWK_03963	4.771e-76	286.0	COG1917@1|root,COG5285@1|root,COG1917@2|Bacteria,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,DUF4437,Haem_oxygenas_2,PhyH
SRR25158390_k127_816575_6	298653.Franean1_1977	1.849e-109	378.0	COG0500@1|root,COG2226@2|Bacteria,2H0T3@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_816575_5	402881.Plav_1705	1.592e-114	382.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,1JN63@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158390_k127_816575_20	1127134.NOCYR_3227	6.266e-38	149.0	2FHIX@1|root,349CW@2|Bacteria,2GN7H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_816575_2	1127134.NOCYR_3228	2.558e-181	610.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_816575_23	749927.AMED_8079	1.335e-27	124.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4E2J5@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR25158390_k127_816575_17	935261.JAGL01000014_gene3634	1.24e-64	247.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfatase
SRR25158390_k127_816575_0	1123501.KB902310_gene60	1.133e-266	829.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158390_k127_818651_1	365528.KB891181_gene4741	8.042e-100	336.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_1,Glycos_transf_2
SRR25158390_k127_818651_0	1120950.KB892707_gene5004	7.465e-144	477.0	COG1362@1|root,COG1362@2|Bacteria,2GKW4@201174|Actinobacteria,4DPTA@85009|Propionibacteriales	201174|Actinobacteria	E	Aminopeptidase I zinc metalloprotease (M18)	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
SRR25158390_k127_818651_6	509190.Cseg_2812	0.0007951	50.0	COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,2TT35@28211|Alphaproteobacteria,2KH8W@204458|Caulobacterales	204458|Caulobacterales	O	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_818651_3	232348.ADXL01000034_gene1375	1.77e-57	206.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1H0VR@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158390_k127_818651_2	469383.Cwoe_1308	1.671e-70	258.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158390_k127_818651_4	397945.Aave_2532	6.853e-43	164.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,4AE2I@80864|Comamonadaceae	28216|Betaproteobacteria	T	low molecular weight phosphotyrosine protein phosphatase	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158390_k127_818651_5	1121106.JQKB01000040_gene1500	1.366e-31	133.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,2U98X@28211|Alphaproteobacteria,2JSPU@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
SRR25158390_k127_840392_10	1313172.YM304_27530	1.916e-41	160.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria	201174|Actinobacteria	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158390_k127_840392_4	1313172.YM304_27520	2.831e-92	317.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CN5T@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_840392_7	1463854.JOHT01000050_gene210	2.166e-72	256.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_840392_11	1229780.BN381_330050	8.342e-25	115.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158390_k127_840392_2	1313172.YM304_27490	2.44e-114	379.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CMWX@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158390_k127_840392_5	1313172.YM304_27480	1.241e-77	268.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CMXN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158390_k127_840392_3	1229780.BN381_330053	3.094e-109	359.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,3UW78@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158390_k127_840392_8	1229780.BN381_330054	5.551e-62	219.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,3UWM3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158390_k127_840392_9	1229780.BN381_330055	5.15e-51	201.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,3UWMF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158390_k127_840392_1	1313172.YM304_27440	5.539e-139	451.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CMRC@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158390_k127_840392_6	1121877.JQKF01000004_gene1129	1.236e-72	263.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CMZX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158390_k127_840392_0	1229780.BN381_330058	1.283e-202	637.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,3UW9H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158390_k127_864664_8	743718.Isova_0275	7.302e-05	46.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_864664_1	208439.AJAP_12500	3.541e-83	285.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria,4EFE8@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_864664_0	296591.Bpro_1404	1.04e-116	395.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2VQB7@28216|Betaproteobacteria,4AFVE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,Sacchrp_dh_NADP
SRR25158390_k127_864664_3	1380390.JIAT01000009_gene1027	3.608e-72	269.0	COG2207@1|root,COG2207@2|Bacteria,2H1NG@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_864664_5	1229780.BN381_100086	3.008e-44	166.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	mazF3	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_864664_4	455632.SGR_5924	8.556e-55	205.0	COG0483@1|root,COG0483@2|Bacteria,2HDIP@201174|Actinobacteria	201174|Actinobacteria	G	Inositol monophosphatase family	strO	-	3.1.3.15	ko:K05602	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158390_k127_864664_2	1229780.BN381_160038	2.918e-72	256.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158390_k127_864664_6	525368.HMPREF0591_4005	2.056e-35	142.0	COG2524@1|root,COG2524@2|Bacteria,2I5GC@201174|Actinobacteria,23A8P@1762|Mycobacteriaceae	201174|Actinobacteria	K	but domain identity suggests it may be a signal-transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_864664_7	1449069.JMLO01000011_gene2487	6.57e-11	63.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4G06V@85025|Nocardiaceae	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_869248_0	929712.KI912613_gene767	6.018e-94	316.0	COG1233@1|root,COG1233@2|Bacteria,2GKRC@201174|Actinobacteria,4CSHY@84995|Rubrobacteria	84995|Rubrobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_869248_5	572477.Alvin_1444	9.228e-06	58.0	COG1403@1|root,COG1403@2|Bacteria,1QE4E@1224|Proteobacteria,1RS5S@1236|Gammaproteobacteria,1WZVU@135613|Chromatiales	135613|Chromatiales	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5,RRXRR
SRR25158390_k127_869248_1	469371.Tbis_0837	8.725e-54	210.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,4E3BW@85010|Pseudonocardiales	201174|Actinobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158390_k127_869248_3	469383.Cwoe_0460	1.066e-14	76.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158390_k127_869248_2	1289387.AUKW01000009_gene4263	2.634e-31	127.0	COG1487@1|root,COG1487@2|Bacteria,2ISD3@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_869248_4	1123023.JIAI01000032_gene4150	1.192e-08	64.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EB4X@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR25158390_k127_878383_6	926550.CLDAP_02880	4.646e-20	91.0	COG2128@1|root,COG2128@2|Bacteria,2G7D8@200795|Chloroflexi	200795|Chloroflexi	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_878383_4	656024.FsymDg_2709	2.649e-61	227.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4ESAK@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158390_k127_878383_3	1380393.JHVP01000004_gene615	7.856e-71	255.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4ESAF@85013|Frankiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158390_k127_878383_7	479434.Sthe_0183	2.412e-13	77.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158390_k127_878383_0	1240349.ANGC01000014_gene628	4.69e-121	407.0	28JCJ@1|root,2Z977@2|Bacteria,2HHS9@201174|Actinobacteria,4FZVC@85025|Nocardiaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158390_k127_878383_2	1121272.KB903279_gene6980	1.872e-89	300.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria,4DCSH@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_878383_5	656024.FsymDg_2709	2.161e-59	214.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4ESAK@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158390_k127_878383_8	1415166.NONO_c57930	0.0002329	50.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria,4FX62@85025|Nocardiaceae	201174|Actinobacteria	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158390_k127_878383_1	1410634.JHVD01000027_gene1655	2.198e-119	397.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158390_k127_890963_0	1240349.ANGC01000033_gene2991	4.713e-118	382.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4FURR@85025|Nocardiaceae	201174|Actinobacteria	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158390_k127_890963_1	1123024.AUII01000010_gene679	2.548e-71	248.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4E0T5@85010|Pseudonocardiales	201174|Actinobacteria	KP	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
SRR25158390_k127_890963_5	1120949.KB903294_gene4051	4.128e-28	120.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_890963_2	675635.Psed_4350	2.689e-56	211.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_890963_4	1449353.JQMQ01000005_gene1822	2.44e-28	124.0	COG0789@1|root,COG0789@2|Bacteria,2I8PU@201174|Actinobacteria,2NH31@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_890963_3	882083.SacmaDRAFT_2363	2.472e-37	144.0	COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria,4E5QJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR25158390_k127_890963_8	1500304.JQKY01000003_gene568	1.045e-08	59.0	COG1309@1|root,COG1309@2|Bacteria,1RE7W@1224|Proteobacteria,2U8AN@28211|Alphaproteobacteria,4B8Y4@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_906693_16	37919.EP51_23160	2.134e-12	75.0	COG1714@1|root,COG1714@2|Bacteria,2IN6K@201174|Actinobacteria,4G1GS@85025|Nocardiaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_906693_17	446468.Ndas_3525	2.945e-12	68.0	COG0500@1|root,COG0500@2|Bacteria,2GM5T@201174|Actinobacteria,4EG1W@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_906693_10	1445613.JALM01000023_gene4329	9.185e-37	152.0	COG0500@1|root,COG2226@2|Bacteria,2HVPX@201174|Actinobacteria,4E2SJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_906693_4	365528.KB891231_gene176	1.974e-72	251.0	2A3AC@1|root,30RSD@2|Bacteria,2IKHP@201174|Actinobacteria,4EVHF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_906693_8	1048339.KB913029_gene3842	8.499e-48	175.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,4ET8M@85013|Frankiales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRR25158390_k127_906693_7	58123.JOFJ01000007_gene751	2.85e-52	198.0	2F9MB@1|root,341XJ@2|Bacteria,2IS9E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_906693_11	469383.Cwoe_0856	1.212e-29	124.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158390_k127_906693_5	1229780.BN381_130352	6.778e-64	227.0	COG2267@1|root,COG2267@2|Bacteria,2IS9U@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_906693_18	590998.Celf_0802	3.083e-08	65.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158390_k127_906693_6	298654.FraEuI1c_1777	1.693e-62	219.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_906693_3	208444.JNYY01000025_gene5964	2.912e-84	312.0	COG1672@1|root,COG2197@1|root,COG1672@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,4EF66@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_906693_9	1123261.AXDW01000007_gene2391	1.041e-41	170.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,1S6NH@1236|Gammaproteobacteria,1X7AS@135614|Xanthomonadales	135614|Xanthomonadales	J	Putative tRNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_bind
SRR25158390_k127_906693_13	1343740.M271_15970	1.462e-17	95.0	COG0776@1|root,COG0776@2|Bacteria,2GV0M@201174|Actinobacteria	201174|Actinobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158390_k127_906693_14	1869.MB27_06920	2.347e-16	88.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria,4DCE2@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_906693_0	1229780.BN381_70027	7.232e-205	667.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,3UX6T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158390_k127_906693_1	1229780.BN381_70026	1.996e-192	608.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWHR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_906693_2	1229780.BN381_290045	1.308e-156	520.0	COG2936@1|root,COG2936@2|Bacteria,2IAA6@201174|Actinobacteria,3UXM3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158390_k127_931642_2	298655.KI912266_gene6070	3.139e-99	329.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EU6F@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_931642_0	298655.KI912266_gene3852	4.394e-214	672.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_931642_1	1078020.KEK_22174	1.978e-200	655.0	COG2030@1|root,COG2030@2|Bacteria,2H7MB@201174|Actinobacteria,232CJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158390_k127_931642_3	298655.KI912266_gene5761	1.442e-84	307.0	COG1024@1|root,COG1024@2|Bacteria,2IDF4@201174|Actinobacteria,4EX6Y@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158390_k127_931642_4	487521.OCU_19440	2.625e-76	260.0	COG1960@1|root,COG1960@2|Bacteria,2IBE0@201174|Actinobacteria,23EV2@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_97812_5	1123258.AQXZ01000017_gene3835	5.666e-70	248.0	2DKYM@1|root,30WWW@2|Bacteria,2IGAV@201174|Actinobacteria,4G9AS@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1353)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1353
SRR25158390_k127_97812_1	1122611.KB903943_gene1586	5.948e-111	367.0	COG0462@1|root,COG0462@2|Bacteria,2H34F@201174|Actinobacteria,4EMNC@85012|Streptosporangiales	201174|Actinobacteria	EF	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
SRR25158390_k127_97812_6	298655.KI912266_gene4457	2.088e-62	222.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_97812_4	1382356.JQMP01000003_gene1746	2.119e-75	265.0	COG1131@1|root,COG1131@2|Bacteria,2G68Y@200795|Chloroflexi,27YUR@189775|Thermomicrobia	189775|Thermomicrobia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_97812_9	1244869.H261_02936	6.703e-15	87.0	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,2TSUF@28211|Alphaproteobacteria,2JQH1@204441|Rhodospirillales	204441|Rhodospirillales	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_97812_2	1123322.KB904702_gene255	3.922e-110	364.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_97812_8	1123322.KB904702_gene253	2.894e-50	193.0	COG1309@1|root,COG1309@2|Bacteria,2IJWX@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_97812_7	1123024.AUII01000020_gene3230	1.929e-53	193.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4E4PZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158390_k127_97812_0	477641.MODMU_2528	7.444e-170	550.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4EUC0@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_97812_10	1172188.KB911820_gene2522	2.44e-12	76.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4FIWM@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_982975_4	1229780.BN381_80216	1.978e-128	422.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_982975_2	1229780.BN381_80218	1.143e-142	466.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_982975_7	1120936.KB907209_gene1768	1.239e-33	139.0	COG0586@1|root,COG0586@2|Bacteria,2HKKQ@201174|Actinobacteria,4EIYT@85012|Streptosporangiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158390_k127_982975_0	570268.ANBB01000058_gene4272	5.527e-151	493.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria,4EJ4K@85012|Streptosporangiales	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRR25158390_k127_982975_8	1151119.KB895498_gene3507	1.447e-32	132.0	COG0071@1|root,COG0071@2|Bacteria,2GQGQ@201174|Actinobacteria,1WBR0@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_982975_9	29306.JOBE01000008_gene4567	6.909e-14	81.0	COG1309@1|root,COG1309@2|Bacteria,2GM6H@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_982975_1	1146883.BLASA_2833	1.582e-145	482.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EUCP@85013|Frankiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_982975_3	1120936.KB907209_gene1792	2.037e-142	477.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
SRR25158390_k127_982975_5	1229780.BN381_50087	8.996e-77	272.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,3UWXI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_982975_6	2002.JOEQ01000005_gene3503	3.663e-39	148.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4EM9K@85012|Streptosporangiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_988146_7	1229780.BN381_70073	9.308e-65	234.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,3UWFU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158390_k127_988146_4	525909.Afer_1991	1.192e-101	341.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CNHS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_988146_1	487521.OCU_11020	5.323e-177	562.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,23617@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA3	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_988146_0	1394178.AWOO02000071_gene380	4.96e-215	670.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4EH3D@85012|Streptosporangiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158390_k127_988146_11	324602.Caur_2582	3.71e-32	141.0	COG1977@1|root,COG1977@2|Bacteria,2G6VH@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_988146_10	1408422.JHYF01000016_gene32	2.85e-41	160.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,24KFX@186801|Clostridia,36MGM@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_988146_13	326424.FRAAL5813	0.0001991	54.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_988146_6	298654.FraEuI1c_1865	5.109e-80	277.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_988146_9	298654.FraEuI1c_1864	4.314e-48	175.0	COG0640@1|root,COG0640@2|Bacteria,2GS8K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_988146_5	298654.FraEuI1c_1863	1.56e-88	293.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_988146_2	1304865.JAGF01000001_gene3609	9.997e-154	495.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4F28I@85016|Cellulomonadaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_988146_8	37919.EP51_12585	5.387e-49	179.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria,4G17F@85025|Nocardiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_988146_3	1206732.BAGD01000026_gene667	2.326e-131	425.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FV5H@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_988146_12	345341.KUTG_01571	6.877e-28	126.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DYQ9@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
## 3269 queries scanned
## Total time (seconds): 13.242732763290405
## Rate: 246.85 q/s