## Mon Dec 15 00:11:41 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158390_bin.20.fa -m mmseqs --itype genome -o SRR25158390_bin.20 --output_dir /data/result/bins/wyx/egg/SRR25158390_bin.20 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158390_k127_1000347_10	1197906.CAJQ02000004_gene3056	1.715e-30	125.0	COG2411@1|root,COG2411@2|Bacteria,1N0KG@1224|Proteobacteria,2UCPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1000347_4	326424.FRAAL1804	2.734e-83	281.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,4EV7M@85013|Frankiales	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158390_k127_1000347_6	1120950.KB892747_gene3676	3.713e-63	222.0	COG0454@1|root,COG0456@2|Bacteria,2I2XB@201174|Actinobacteria,4DQWV@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_1000347_0	1120950.KB892747_gene3674	2.352e-171	541.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4DNME@85009|Propionibacteriales	201174|Actinobacteria	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158390_k127_1000347_9	862751.SACTE_3266	6.513e-44	179.0	COG3460@1|root,COG3460@2|Bacteria,2IKMJ@201174|Actinobacteria	201174|Actinobacteria	Q	Phenylacetate-CoA oxygenase	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR25158390_k127_1000347_3	1120950.KB892747_gene3672	1.435e-97	331.0	COG3396@1|root,COG3396@2|Bacteria,2GJIU@201174|Actinobacteria,4DQ8B@85009|Propionibacteriales	201174|Actinobacteria	S	Phenylacetic acid catabolic protein	paaI	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158390_k127_1000347_7	494419.ALPM01000030_gene3090	7.082e-56	205.0	COG2151@1|root,COG2151@2|Bacteria,2II4H@201174|Actinobacteria,1W96G@1268|Micrococcaceae	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158390_k127_1000347_2	1122138.AQUZ01000010_gene5127	8.482e-131	431.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4DNQQ@85009|Propionibacteriales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	paaK	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158390_k127_1000347_8	196162.Noca_2312	4.645e-49	184.0	COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4DRHC@85009|Propionibacteriales	201174|Actinobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1,NUDIX
SRR25158390_k127_1000347_1	1385518.N798_15750	1.347e-136	437.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4FFQE@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRR25158390_k127_1000347_5	298654.FraEuI1c_1122	9.21e-79	281.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4ERIQ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158390_k127_1006210_0	44060.JODL01000005_gene651	0.0	1203.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158390_k127_1006210_1	1298863.AUEP01000003_gene2720	3.624e-178	586.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158390_k127_1006210_3	710696.Intca_0369	6.706e-27	128.0	COG0596@1|root,COG1506@1|root,COG3710@1|root,COG0596@2|Bacteria,COG1506@2|Bacteria,COG3710@2|Bacteria,2HASC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158390_k127_1006210_2	479435.Kfla_2480	4.808e-65	225.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DNZA@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158390_k127_1012562_3	222534.KB893728_gene5458	4.279e-42	158.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria,4EVDB@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1012562_1	479431.Namu_2609	2.249e-114	389.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4EUC0@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_1012562_0	164757.Mjls_3389	7.254e-135	443.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria,235MW@1762|Mycobacteriaceae	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_1012562_2	1240349.ANGC01000040_gene4382	1.659e-79	276.0	COG0477@1|root,COG2814@2|Bacteria,2GMK6@201174|Actinobacteria,4FZZF@85025|Nocardiaceae	201174|Actinobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4
SRR25158390_k127_1017183_2	1068978.AMETH_4939	8.458e-92	310.0	COG1051@1|root,COG1051@2|Bacteria,2I2YK@201174|Actinobacteria,4E3FE@85010|Pseudonocardiales	201174|Actinobacteria	F	ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_1017183_0	1120950.KB892756_gene6665	1.444e-96	319.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4DQ2S@85009|Propionibacteriales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_1017183_6	479435.Kfla_6584	1.814e-41	156.0	2DNXR@1|root,32ZPP@2|Bacteria,2I2KW@201174|Actinobacteria,4DSD9@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158390_k127_1017183_5	1146883.BLASA_0139	1.279e-42	168.0	2DNRF@1|root,32YSD@2|Bacteria,2IAJC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1017183_3	1133849.O3I_036375	1.398e-86	302.0	COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,4FZGG@85025|Nocardiaceae	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158390_k127_1017183_4	1169161.KB897727_gene915	2.463e-71	247.0	COG1670@1|root,COG1670@2|Bacteria,2I4GW@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158390_k127_1017183_1	1179773.BN6_58270	4.169e-93	309.0	COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria,4E90C@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_1019634_3	196162.Noca_1803	2.225e-114	375.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,4DTCJ@85009|Propionibacteriales	201174|Actinobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158390_k127_1019634_0	1089544.KB912942_gene1878	5.609e-280	882.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4DXAD@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158390_k127_1019634_10	1125971.ASJB01000031_gene1252	5.746e-25	110.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4EF6A@85010|Pseudonocardiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158390_k127_1019634_5	882083.SacmaDRAFT_3107	4.535e-56	208.0	2DU40@1|root,33NV5@2|Bacteria,2GTWE@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR25158390_k127_1019634_2	1445613.JALM01000081_gene984	3.557e-130	435.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DXXN@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1019634_8	479432.Sros_4816	1.489e-42	164.0	COG0071@1|root,COG0071@2|Bacteria,2GQGQ@201174|Actinobacteria,4EQWZ@85012|Streptosporangiales	201174|Actinobacteria	O	Hsp20/alpha crystallin family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_1019634_7	1122611.KB903944_gene1118	2.655e-45	181.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4EQE3@85012|Streptosporangiales	201174|Actinobacteria	C	Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158390_k127_1019634_11	1150864.MILUP08_41671	2.327e-10	69.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DA2C@85008|Micromonosporales	201174|Actinobacteria	CK	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_1019634_6	479435.Kfla_3354	1.394e-48	183.0	COG1028@1|root,COG1028@2|Bacteria,2IN8D@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
SRR25158390_k127_1019634_1	1463820.JOGW01000005_gene3327	6.171e-166	527.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_1019634_9	1313172.YM304_17310	1.466e-33	134.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158390_k127_1019634_4	1385519.N801_12795	1.082e-110	383.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_1028087_1	1380393.JHVP01000004_gene635	2.584e-18	90.0	2EA0E@1|root,3345W@2|Bacteria,2GR4C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1028087_3	1304865.JAGF01000001_gene3323	0.0001373	48.0	28PN6@1|root,2ZCB1@2|Bacteria,2INN5@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158390_k127_1028087_0	196162.Noca_4965	1.799e-48	178.0	28PN6@1|root,2ZCB1@2|Bacteria,2INN5@201174|Actinobacteria,4DW3I@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158390_k127_1028087_2	926554.KI912671_gene374	6.811e-09	60.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_1030124_0	65497.JODV01000008_gene87	0.0	1732.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DYUS@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158390_k127_1030124_3	928724.SacglDRAFT_03072	2.801e-133	432.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria,4DX6J@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM pfkB family carbohydrate kinase	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158390_k127_1030124_2	1463825.JNXC01000018_gene6819	2.315e-208	655.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4DXAM@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158390_k127_1030124_1	882083.SacmaDRAFT_3667	8.894e-241	751.0	COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,2IAU4@201174|Actinobacteria,4E21M@85010|Pseudonocardiales	201174|Actinobacteria	MQ	PFAM Methyltransferase domain	-	-	2.1.1.156,2.1.1.157	ko:K18896,ko:K18897	ko00260,map00260	-	R10060,R10061	RC00003,RC03038,RC03040	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1031882_0	1120936.KB907211_gene31	0.0	1906.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4EN5U@85012|Streptosporangiales	201174|Actinobacteria	FL	LAGLIDADG-like domain	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158390_k127_1031882_12	1120950.KB892707_gene4594	8.674e-68	238.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4DQJU@85009|Propionibacteriales	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158390_k127_1031882_15	1033730.CAHG01000013_gene1443	2.669e-12	76.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,4DSQE@85009|Propionibacteriales	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158390_k127_1031882_11	43354.JOIJ01000003_gene3965	6.802e-94	314.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4E040@85010|Pseudonocardiales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158390_k127_1031882_2	1120950.KB892707_gene4587	1.187e-238	756.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4DN8C@85009|Propionibacteriales	201174|Actinobacteria	KL	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158390_k127_1031882_1	1120950.KB892707_gene4586	9.97e-282	880.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4DTZJ@85009|Propionibacteriales	201174|Actinobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158390_k127_1031882_5	208444.JNYY01000006_gene6919	3.181e-173	547.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4DXVJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158390_k127_1031882_14	43354.JOIJ01000007_gene1727	1.897e-17	86.0	COG1977@1|root,COG1977@2|Bacteria,2IQIT@201174|Actinobacteria,4E6FW@85010|Pseudonocardiales	201174|Actinobacteria	H	Molybdopterin converting factor, small subunit	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_1031882_3	1120950.KB892707_gene4581	1.511e-199	631.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4DNPS@85009|Propionibacteriales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158390_k127_1031882_10	1157637.KB892116_gene129	2.17e-98	331.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158390_k127_1031882_8	1122138.AQUZ01000043_gene3314	9.997e-128	415.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4DP56@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158390_k127_1031882_13	953739.SVEN_5462	1.279e-53	204.0	COG3885@1|root,COG3885@2|Bacteria,2GN3T@201174|Actinobacteria	201174|Actinobacteria	S	ferrous iron binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1031882_4	369723.Strop_3819	1.452e-175	572.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DB15@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1031882_6	263358.VAB18032_00605	2.697e-164	523.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4D8TJ@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1031882_9	391037.Sare_4211	5.51e-117	385.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4DAPV@85008|Micromonosporales	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_1031882_7	263358.VAB18032_00615	2.986e-155	496.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DH79@85008|Micromonosporales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158390_k127_1043420_1	1122609.AUGT01000022_gene718	3.544e-97	327.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DNXK@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158390_k127_1043420_2	1120950.KB892747_gene3686	7.646e-37	142.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DS16@85009|Propionibacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158390_k127_1043420_0	1463856.JOHY01000041_gene7222	9.696e-194	612.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158390_k127_1052008_6	1121926.AXWO01000041_gene2631	7.235e-74	262.0	COG2334@1|root,COG2334@2|Bacteria,2GXZI@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1052008_2	1121933.AUHH01000051_gene290	1.382e-129	421.0	COG1948@1|root,COG1948@2|Bacteria,2HAMQ@201174|Actinobacteria,4DTJV@85009|Propionibacteriales	201174|Actinobacteria	L	ERCC4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ERCC4,Lsr2
SRR25158390_k127_1052008_7	68194.JNXR01000015_gene7789	9.683e-21	100.0	2ECD9@1|root,336BH@2|Bacteria,2I6UD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1052008_0	44060.JODL01000002_gene2257	5.876e-264	821.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	bhbA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158390_k127_1052008_4	446469.Sked_25760	8.759e-122	401.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria	201174|Actinobacteria	S	basic membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158390_k127_1052008_1	935839.JAGJ01000010_gene374	3.173e-224	706.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4F44H@85017|Promicromonosporaceae	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158390_k127_1052008_3	494419.ALPM01000097_gene402	2.287e-125	413.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,1W833@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158390_k127_1052008_5	1713.JOFV01000008_gene3062	2.945e-78	269.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4F0KC@85016|Cellulomonadaceae	201174|Actinobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158390_k127_109436_1	1120950.KB892760_gene5788	2.657e-95	322.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DNHH@85009|Propionibacteriales	201174|Actinobacteria	F	Adenosine/AMP deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158390_k127_109436_0	935839.JAGJ01000010_gene339	1.207e-199	634.0	COG1292@1|root,COG1292@2|Bacteria,2GJX0@201174|Actinobacteria,4F34H@85017|Promicromonosporaceae	201174|Actinobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
SRR25158390_k127_1098853_0	298654.FraEuI1c_0703	3.468e-57	209.0	COG3503@1|root,COG3503@2|Bacteria,2I2JM@201174|Actinobacteria,4EV74@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
SRR25158390_k127_1098853_4	1713.JOFV01000003_gene1553	1.176e-09	68.0	COG4709@1|root,COG4709@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
SRR25158390_k127_1098853_2	710696.Intca_3437	2.571e-40	153.0	COG1695@1|root,COG1695@2|Bacteria,2GRHC@201174|Actinobacteria,4FH26@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR25158390_k127_1098853_3	1123065.ATWL01000010_gene3033	4.322e-26	115.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158390_k127_1098853_1	1045009.AFXQ01000002_gene1503	6.793e-54	194.0	COG1528@1|root,COG1528@2|Bacteria,2IIT3@201174|Actinobacteria,1W97S@1268|Micrococcaceae	201174|Actinobacteria	P	Iron-storage protein	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158390_k127_1099484_0	1120950.KB892768_gene5266	7.954e-116	376.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria,4DN4U@85009|Propionibacteriales	201174|Actinobacteria	L	Helix-hairpin-helix domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRR25158390_k127_1099484_3	479435.Kfla_3101	8.208e-79	271.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4DSHX@85009|Propionibacteriales	201174|Actinobacteria	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
SRR25158390_k127_1099484_4	1123319.AUBE01000008_gene3933	2.341e-75	258.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_1099484_5	266940.Krad_1906	1.385e-28	125.0	2ETKA@1|root,33M3Y@2|Bacteria,2H03F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1099484_6	35754.JNYJ01000022_gene8125	5.563e-25	118.0	COG0443@1|root,COG0443@2|Bacteria,2GMNN@201174|Actinobacteria,4D91S@85008|Micromonosporales	201174|Actinobacteria	O	Hsp70 protein	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70
SRR25158390_k127_1099484_2	2002.JOEQ01000004_gene2722	4.403e-86	301.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4EHB9@85012|Streptosporangiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158390_k127_1099484_1	469371.Tbis_1115	1.034e-115	387.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4DX3X@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_1099484_7	1304865.JAGF01000001_gene2867	3.576e-23	102.0	COG3360@1|root,COG3360@2|Bacteria,2HY46@201174|Actinobacteria,4F2YC@85016|Cellulomonadaceae	201174|Actinobacteria	S	Dodecin	-	-	-	-	-	-	-	-	-	-	-	-	Dodecin
SRR25158390_k127_1099484_8	365528.KB891274_gene2785	5.964e-05	49.0	COG2197@1|root,COG2197@2|Bacteria,2I2R1@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_1104398_5	1120950.KB892749_gene3376	3.836e-100	335.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4DP1P@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158390_k127_1104398_2	1120950.KB892768_gene5364	1.192e-131	426.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4DN4N@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158390_k127_1104398_6	1120950.KB892749_gene3363	7.641e-98	325.0	COG0813@1|root,COG0813@2|Bacteria,2GNT6@201174|Actinobacteria,4DPAS@85009|Propionibacteriales	201174|Actinobacteria	F	Phosphorylase superfamily	deoD	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158390_k127_1104398_4	469371.Tbis_2968	8.195e-102	352.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4DXT4@85010|Pseudonocardiales	201174|Actinobacteria	L	NADH pyrophosphatase	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
SRR25158390_k127_1104398_10	408672.NBCG_05659	3.035e-27	112.0	COG0695@1|root,COG0695@2|Bacteria,2IQF9@201174|Actinobacteria,4DRV4@85009|Propionibacteriales	201174|Actinobacteria	O	Glutaredoxin	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
SRR25158390_k127_1104398_0	1120950.KB892749_gene3360	1.102e-261	824.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DNWV@85009|Propionibacteriales	201174|Actinobacteria	L	HRDC domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158390_k127_1104398_9	1120950.KB892749_gene3359	4.411e-34	136.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria,4DRK7@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	-	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR25158390_k127_1104398_11	1172181.KB911720_gene4137	1.744e-12	72.0	2ER9N@1|root,33IV9@2|Bacteria,2GSJ1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1104398_3	1122622.ATWJ01000012_gene1038	7.63e-115	377.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4FE5G@85021|Intrasporangiaceae	201174|Actinobacteria	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028,ko:K17076	ko02010,map02010	M00236,M00589	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.20	-	-	ABC_tran
SRR25158390_k127_1104398_7	494419.ALPM01000029_gene3147	7.617e-84	289.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,1W7G1@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter permease	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158390_k127_1104398_8	494419.ALPM01000029_gene3146	7.407e-73	255.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,1W95W@1268|Micrococcaceae	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158390_k127_1104398_1	1120950.KB892749_gene3356	1.231e-199	630.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DNKT@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
SRR25158390_k127_1110808_1	469383.Cwoe_0903	5.084e-129	419.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4CPQU@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158390_k127_1110808_3	2074.JNYD01000016_gene4196	2.677e-94	316.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4DY5K@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, deoR family	glpR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
SRR25158390_k127_1110808_0	67373.JOBF01000030_gene1763	1.448e-132	435.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria	201174|Actinobacteria	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRR25158390_k127_1110808_2	882082.SaccyDRAFT_1764	1.01e-123	412.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4E015@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158390_k127_1110808_4	1386089.N865_05060	4.866e-89	298.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4FGV3@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_1119218_0	1463853.JOHW01000036_gene1663	5.329e-117	385.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8,TAT_signal
SRR25158390_k127_1119218_1	644283.Micau_0965	2.33e-80	271.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DCE9@85008|Micromonosporales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158390_k127_1147382_3	479435.Kfla_2421	8.67e-155	497.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DPI2@85009|Propionibacteriales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158390_k127_1147382_5	235985.BBPN01000007_gene3319	7.029e-63	222.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,2NHIA@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterized protein family UPF0054	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158390_k127_1147382_1	1120950.KB892739_gene3991	8.22e-165	531.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4DNND@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_1147382_7	512565.AMIS_11840	2.03e-24	116.0	COG0295@1|root,COG0295@2|Bacteria,2IM42@201174|Actinobacteria,4DEC2@85008|Micromonosporales	201174|Actinobacteria	F	cytidine deaminase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1147382_0	1120950.KB892762_gene5499	1.631e-170	563.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DPA4@85009|Propionibacteriales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158390_k127_1147382_2	1123321.KB905815_gene3731	7.41e-157	501.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria	201174|Actinobacteria	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158390_k127_1147382_4	1123065.ATWL01000008_gene2533	8.035e-130	423.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158390_k127_1147382_6	1151126.AQYI01000004_gene1145	1.677e-47	176.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4FKQS@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158390_k127_1151646_3	743718.Isova_0784	3.734e-135	437.0	COG1070@1|root,COG1070@2|Bacteria,2GVSJ@201174|Actinobacteria,4F3YV@85017|Promicromonosporaceae	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, C-terminal domain	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_1151646_4	1122611.KB903968_gene2278	1.55e-130	424.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4EHAQ@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158390_k127_1151646_1	1120950.KB892747_gene3725	5.391e-181	575.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4DND1@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158390_k127_1151646_2	28444.JODQ01000016_gene7150	6.551e-152	492.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4EFKK@85012|Streptosporangiales	201174|Actinobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	rip1	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158390_k127_1151646_0	1121385.AQXW01000003_gene581	4.262e-210	658.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,1ZVRI@145357|Dermacoccaceae	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158390_k127_1153051_6	1713.JOFV01000011_gene2472	2.169e-119	391.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4F22I@85016|Cellulomonadaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
SRR25158390_k127_1153051_7	1120950.KB892779_gene963	1.261e-89	299.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4DP1W@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR25158390_k127_1153051_9	1240349.ANGC01000026_gene3701	7.45e-72	255.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4FX5D@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158390_k127_1153051_10	1137268.AZXF01000005_gene3098	1.156e-39	149.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4EJPX@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158390_k127_1153051_0	1120950.KB892779_gene960	3.446e-265	829.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DP65@85009|Propionibacteriales	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158390_k127_1153051_2	1122138.AQUZ01000056_gene6951	1.222e-178	572.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4DPXE@85009|Propionibacteriales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_1153051_1	1120950.KB892779_gene958	9.837e-190	608.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4DNIM@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_1153051_4	1048339.KB913029_gene2590	1.031e-128	419.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4ERU8@85013|Frankiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158390_k127_1153051_3	479435.Kfla_6806	1.329e-136	450.0	COG0745@1|root,COG3284@1|root,COG0745@2|Bacteria,COG3284@2|Bacteria,2GJV4@201174|Actinobacteria,4DN1C@85009|Propionibacteriales	201174|Actinobacteria	KQ	Transcriptional activator of acetoin glycerol metabolism	-	-	-	-	-	-	-	-	-	-	-	-	GAF
SRR25158390_k127_1153051_11	4792.ETI46610	1.092e-22	111.0	29H2K@1|root,2RQ99@2759|Eukaryota,3Q976@4776|Peronosporales	4776|Peronosporales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1153051_8	1144312.PMI09_03328	5.677e-76	262.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,4BM3M@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_1153051_5	1500301.JQMF01000038_gene5909	1.059e-126	429.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,4B9HU@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	MA20_29500	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158390_k127_1162221_18	471852.Tcur_2151	6.976e-08	58.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4EGVP@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158390_k127_1162221_8	644283.Micau_4680	3.964e-91	309.0	COG3173@1|root,COG3173@2|Bacteria,2GMHD@201174|Actinobacteria,4DBQF@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1162221_2	1906.SFRA_30705	5.861e-194	617.0	COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158390_k127_1162221_3	1906.SFRA_30710	5.231e-193	638.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158390_k127_1162221_9	1095767.CAHD01000157_gene3038	2.473e-89	302.0	COG0300@1|root,COG0300@2|Bacteria,2IEDC@201174|Actinobacteria,4F1AE@85016|Cellulomonadaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1162221_0	1120950.KB892768_gene5214	0.0	1063.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4DPEJ@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158390_k127_1162221_1	1120950.KB892768_gene5215	1.446e-200	631.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4DPA8@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158390_k127_1162221_6	65497.JODV01000004_gene1508	4.954e-112	369.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria,4E37G@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	argI	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_1162221_4	469371.Tbis_0134	1.577e-188	599.0	COG1115@1|root,COG1115@2|Bacteria,2GIU2@201174|Actinobacteria,4DZWP@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM amino acid carrier protein	alaP	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
SRR25158390_k127_1162221_11	1352941.M877_34035	1.515e-84	288.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158390_k127_1162221_14	500153.JOEK01000010_gene4563	6.539e-56	197.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158390_k127_1162221_17	1169161.KB897725_gene1663	4.014e-19	92.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158390_k127_1162221_10	479435.Kfla_5455	6.653e-87	295.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DNG8@85009|Propionibacteriales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158390_k127_1162221_16	570268.ANBB01000002_gene362	5.738e-26	117.0	COG1404@1|root,COG1404@2|Bacteria,2GMN0@201174|Actinobacteria,4EK90@85012|Streptosporangiales	201174|Actinobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
SRR25158390_k127_1162221_13	42256.RradSPS_0150	1.776e-65	229.0	COG0572@1|root,COG0572@2|Bacteria,2HQC8@201174|Actinobacteria	201174|Actinobacteria	F	belongs to the nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,Cytidylate_kin
SRR25158390_k127_1162221_5	33876.JNXY01000005_gene8613	5.368e-162	529.0	COG1409@1|root,COG1409@2|Bacteria,2GP1M@201174|Actinobacteria,4DBV7@85008|Micromonosporales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158390_k127_1162221_7	1120950.KB892707_gene4712	1.66e-108	358.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4DNZB@85009|Propionibacteriales	201174|Actinobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158390_k127_1162221_15	2002.JOEQ01000002_gene4499	3.234e-32	126.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4EK7H@85012|Streptosporangiales	201174|Actinobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
SRR25158390_k127_1162221_12	1463887.KL590009_gene3204	1.057e-66	231.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158390_k127_1164569_1	298654.FraEuI1c_6190	1.005e-129	424.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4ERH5@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158390_k127_1164569_0	1352941.M877_24300	9.693e-209	662.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1164569_2	2045.KR76_06645	2.153e-34	135.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4DN6W@85009|Propionibacteriales	201174|Actinobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158390_k127_1172172_1	479435.Kfla_6159	1.425e-115	383.0	COG0477@1|root,COG2814@2|Bacteria,2H0CW@201174|Actinobacteria,4DN0M@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1172172_5	1120949.KB903322_gene2739	6.862e-63	222.0	COG3832@1|root,COG3832@2|Bacteria,2HWRC@201174|Actinobacteria,4DK2R@85008|Micromonosporales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_1172172_4	1996.JOFO01000022_gene2629	1.095e-81	275.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4EHYC@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158390_k127_1172172_6	585531.HMPREF0063_12749	1.545e-58	215.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_1172172_3	479433.Caci_8432	7.916e-89	310.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158390_k127_1172172_0	500153.JOEK01000001_gene3549	1.477e-124	409.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria	201174|Actinobacteria	S	protein, coenzyme F420 biosynthesis associated	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158390_k127_1172172_2	1048339.KB913029_gene2248	1.068e-97	330.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4ERWN@85013|Frankiales	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158390_k127_1172172_7	279238.Saro_2220	1.519e-18	98.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,2K39Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
SRR25158390_k127_1172172_8	1123013.AUIC01000002_gene1106	3.419e-18	85.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4FM07@85023|Microbacteriaceae	201174|Actinobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158390_k127_1182516_1	1048339.KB913029_gene4197	8.503e-187	589.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4ERPJ@85013|Frankiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158390_k127_1182516_4	446470.Snas_6189	3.604e-65	239.0	COG0500@1|root,COG2226@2|Bacteria,2I636@201174|Actinobacteria,4EZP0@85014|Glycomycetales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1182516_6	644283.Micau_4996	1.423e-35	151.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4DIUK@85008|Micromonosporales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158390_k127_1182516_0	1306174.JODP01000013_gene7534	3.18e-302	935.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158390_k127_1182516_3	1179773.BN6_24850	7.001e-155	504.0	COG1372@1|root,COG1533@1|root,COG1372@2|Bacteria,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4DXBF@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_1182516_2	1120949.KB903350_gene8297	5.079e-186	595.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DAIU@85008|Micromonosporales	201174|Actinobacteria	J	Histidine--tRNA ligase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158390_k127_1182516_5	1121017.AUFG01000034_gene356	4.671e-55	198.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4FEMC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_1186463_9	1303692.SFUL_3018	5.087e-31	124.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_1186463_0	1121272.KB903283_gene5065	7.675e-225	702.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4DABS@85008|Micromonosporales	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1186463_7	1121272.KB903283_gene5066	9.769e-47	173.0	COG1846@1|root,COG1846@2|Bacteria,2IMUX@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_1186463_4	1121272.KB903283_gene5067	1.173e-98	326.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria,4DCQ8@85008|Micromonosporales	201174|Actinobacteria	S	FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158390_k127_1186463_8	1121385.AQXW01000002_gene79	1.248e-36	141.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,1ZW3M@145357|Dermacoccaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158390_k127_1186463_6	1121946.AUAX01000016_gene4653	2.34e-55	207.0	2C6J1@1|root,33H0F@2|Bacteria,2IMXS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1186463_2	1463825.JNXC01000005_gene2369	2.814e-123	402.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4E06E@85010|Pseudonocardiales	201174|Actinobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158390_k127_1186463_3	479435.Kfla_6400	2.358e-115	382.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4DNEJ@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158390_k127_1186463_5	1120950.KB892755_gene5947	1.022e-82	283.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4DV41@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1186463_1	561175.KB894093_gene4312	1.415e-155	499.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4EGFY@85012|Streptosporangiales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158390_k127_1189926_1	263358.VAB18032_18980	0.0009762	49.0	COG3291@1|root,COG3291@2|Bacteria,2I5PU@201174|Actinobacteria,4DMPN@85008|Micromonosporales	201174|Actinobacteria	M	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36
SRR25158390_k127_1189926_0	1068978.AMETH_3972	2.851e-244	761.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4E5FD@85010|Pseudonocardiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
SRR25158390_k127_1193767_0	713586.KB900536_gene1962	1.374e-283	884.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase S15	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158390_k127_1193767_3	1146883.BLASA_1042	2.726e-80	288.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4ET4Q@85013|Frankiales	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1193767_2	1121946.AUAX01000002_gene104	4.149e-83	284.0	COG3593@1|root,COG3593@2|Bacteria,2GMN5@201174|Actinobacteria,4DEFR@85008|Micromonosporales	201174|Actinobacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1193767_4	1120950.KB892801_gene1765	6.897e-46	173.0	COG0454@1|root,COG0456@2|Bacteria,2GQGN@201174|Actinobacteria,4DS9Y@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_1193767_1	1121272.KB903249_gene1218	1.127e-267	841.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D9JQ@85008|Micromonosporales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_1193767_5	1203190.CAJP01000020_gene573	4.948e-22	98.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,22NI2@1653|Corynebacteriaceae	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_1198850_5	469371.Tbis_1221	1.799e-154	497.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4DYVV@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
SRR25158390_k127_1198850_0	405948.SACE_2467	0.0	1366.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E0QS@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.8	ko:K01537,ko:K12953	-	-	-	-	ko00000,ko01000	3.A.3,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_1198850_10	479432.Sros_3592	2.138e-107	353.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4EHMN@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158390_k127_1198850_16	2074.JNYD01000002_gene5591	1.646e-44	166.0	COG0071@1|root,COG0071@2|Bacteria,2GQGQ@201174|Actinobacteria,4E6NB@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp20/alpha crystallin family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_1198850_13	1449346.JQMO01000002_gene582	2.909e-65	234.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,2M302@2063|Kitasatospora	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_1198850_24	234267.Acid_1882	4.534e-07	62.0	2DF1J@1|root,2ZQ4G@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158390_k127_1198850_21	1449353.JQMQ01000004_gene6164	2.631e-14	84.0	COG0236@1|root,COG0236@2|Bacteria,2GRZ8@201174|Actinobacteria	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR25158390_k127_1198850_8	55952.BU52_03405	6.784e-137	452.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158390_k127_1198850_4	1449976.KALB_4171	1.424e-163	537.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DZDF@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158390_k127_1198850_6	1125971.ASJB01000031_gene1287	7.745e-146	477.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4E12D@85010|Pseudonocardiales	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158390_k127_1198850_1	1449976.KALB_4169	6.867e-290	899.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria,4E1U5@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_1198850_25	1304865.JAGF01000001_gene108	6.445e-05	51.0	2EDP7@1|root,337IW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1198850_12	1101188.KI912156_gene3798	1.68e-73	258.0	29KBT@1|root,30793@2|Bacteria,2IE0E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_AC39
SRR25158390_k127_1198850_9	1449976.KALB_4141	3.618e-131	435.0	COG1269@1|root,COG1269@2|Bacteria,2I9VH@201174|Actinobacteria,4E24W@85010|Pseudonocardiales	201174|Actinobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158390_k127_1198850_20	446470.Snas_3459	1.249e-23	115.0	COG0636@1|root,COG0636@2|Bacteria,2IS0Q@201174|Actinobacteria	201174|Actinobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158390_k127_1198850_26	55952.BU52_25990	7.549e-05	48.0	COG1436@1|root,COG1436@2|Bacteria,2I80G@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1198850_19	284031.JNXD01000003_gene3713	2.641e-24	110.0	COG1390@1|root,COG1390@2|Bacteria,2GT2F@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
SRR25158390_k127_1198850_2	1101188.KI912156_gene3793	4.241e-227	722.0	COG1155@1|root,COG1155@2|Bacteria,2HESQ@201174|Actinobacteria	201174|Actinobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SRR25158390_k127_1198850_7	529709.PYCH_15750	5.194e-140	459.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2433N@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158390_k127_1198850_17	1101188.KI912156_gene3791	1.461e-38	155.0	COG1394@1|root,COG1394@2|Bacteria,2INZB@201174|Actinobacteria	201174|Actinobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SRR25158390_k127_1198850_22	1304865.JAGF01000001_gene99	2.912e-13	76.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	uspE	GO:0000302,GO:0001539,GO:0006928,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0033554,GO:0034599,GO:0034614,GO:0034644,GO:0035690,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042710,GO:0044010,GO:0044764,GO:0046677,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071478,GO:0071482,GO:0071973,GO:0097237,GO:0097588,GO:0104004,GO:1901700,GO:1901701	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
SRR25158390_k127_1198850_3	926564.KI911765_gene4541	9.912e-197	623.0	COG3103@1|root,COG4991@2|Bacteria,2GJE2@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRR25158390_k127_1198850_15	429009.Adeg_0833	1.997e-45	181.0	COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,25ERN@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.348	ko:K06338,ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_1198850_14	357808.RoseRS_0904	6.681e-50	195.0	COG1262@1|root,COG1262@2|Bacteria,2GACQ@200795|Chloroflexi,375EB@32061|Chloroflexia	32061|Chloroflexia	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
SRR25158390_k127_1198850_27	1003195.SCAT_0116	0.0002096	53.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_1198850_18	102129.Lepto7375DRAFT_7486	1.659e-25	110.0	2E91Y@1|root,333B3@2|Bacteria,1GF50@1117|Cyanobacteria,1HG6K@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1198850_11	1121272.KB903290_gene4729	2.735e-97	321.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4DEM5@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158390_k127_1203097_1	67332.FM21_25860	8.787e-164	540.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158390_k127_1203097_2	1120950.KB892784_gene185	2.25e-133	451.0	COG1072@1|root,COG1072@2|Bacteria,2GIRR@201174|Actinobacteria,4DPFH@85009|Propionibacteriales	201174|Actinobacteria	H	pantothenate kinase activity	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158390_k127_1203097_0	1120950.KB892784_gene183	2.731e-190	603.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DNFP@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158390_k127_1203097_4	1122609.AUGT01000009_gene3481	7.775e-59	211.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4DQN0@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158390_k127_1203097_3	1449355.JQNR01000005_gene3742	1.773e-76	258.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158390_k127_1203097_5	471852.Tcur_2294	0.000718	48.0	2F46V@1|root,33WXW@2|Bacteria,2II56@201174|Actinobacteria,4EJU4@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1239061_3	1033736.CAHK01000037_gene2452	3.975e-45	170.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4FAQQ@85019|Brevibacteriaceae	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	braD	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1239061_0	710696.Intca_0363	7.13e-276	863.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4FIPA@85021|Intrasporangiaceae	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_1239061_1	1122622.ATWJ01000013_gene55	2.608e-117	383.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4FFTD@85021|Intrasporangiaceae	201174|Actinobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_1239061_2	710696.Intca_0365	3.293e-52	193.0	COG1414@1|root,COG1414@2|Bacteria,2IJ1N@201174|Actinobacteria,4FIN8@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158390_k127_1239061_4	1169152.AXVD01000022_gene2130	1.035e-29	122.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4FVWN@85025|Nocardiaceae	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158390_k127_1244114_11	44060.JODL01000006_gene1338	1.963e-05	47.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158390_k127_1244114_3	1267535.KB906767_gene2792	1.129e-122	400.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_1244114_0	1463825.JNXC01000001_gene5658	3.808e-183	579.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4DXR1@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_1244114_8	1502724.FF80_00192	4.008e-51	185.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,2U845@28211|Alphaproteobacteria,3N8H9@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_1244114_10	585531.HMPREF0063_12069	3.96e-48	175.0	COG0640@1|root,COG0640@2|Bacteria,2IKUI@201174|Actinobacteria,4DRM5@85009|Propionibacteriales	201174|Actinobacteria	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158390_k127_1244114_4	397278.JOJN01000001_gene2904	1.443e-96	325.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4DNET@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158390_k127_1244114_1	526225.Gobs_2857	1.371e-137	448.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_1244114_5	37919.EP51_38665	6.495e-92	307.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4FZ82@85025|Nocardiaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_1244114_6	298655.KI912266_gene556	3.102e-82	274.0	COG3832@1|root,COG3832@2|Bacteria,2IHN6@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_1244114_9	298655.KI912266_gene557	1.922e-48	181.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_1244114_7	1386089.N865_13005	2.484e-77	261.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria,4FH38@85021|Intrasporangiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_1244114_2	471853.Bcav_2086	8.17e-130	418.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158390_k127_1248583_5	1246448.ANAZ01000002_gene3801	5.925e-14	72.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4EJ8M@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_1248583_0	1120950.KB892708_gene4382	0.0	1135.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DNVE@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158390_k127_1248583_2	1463895.JODA01000044_gene2189	2.003e-68	237.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_1248583_3	66373.JOFQ01000014_gene2703	1.411e-66	233.0	COG2207@1|root,COG2207@2|Bacteria,2GWDZ@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_1248583_4	345341.KUTG_06495	2.234e-54	193.0	COG0346@1|root,COG0346@2|Bacteria,2IKKR@201174|Actinobacteria,4E5JI@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1248583_1	1449346.JQMO01000002_gene1730	2.463e-95	316.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,2M0N5@2063|Kitasatospora	201174|Actinobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158390_k127_1253535_0	1120936.KB907208_gene1063	1.635e-105	350.0	COG4262@1|root,COG4262@2|Bacteria,2GK41@201174|Actinobacteria,4EHG0@85012|Streptosporangiales	201174|Actinobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158390_k127_1253535_3	1127134.NOCYR_4107	2.276e-29	123.0	COG3766@1|root,COG3766@2|Bacteria,2IFF9@201174|Actinobacteria,4G0NN@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158390_k127_1253535_4	457429.ABJI02000723_gene4019	0.0001508	50.0	2DPAM@1|root,3319D@2|Bacteria,2IQTE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4247)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4247
SRR25158390_k127_1253535_2	1237500.ANBA01000028_gene4920	4.809e-35	141.0	2E4HX@1|root,32ZD0@2|Bacteria,2GN9G@201174|Actinobacteria,4EKFC@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF2617	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	DUF2617
SRR25158390_k127_1253535_1	561175.KB894095_gene2285	3.682e-74	254.0	2A0M8@1|root,30NRI@2|Bacteria,2I7PN@201174|Actinobacteria,4EJ4Y@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158390_k127_1270155_5	446470.Snas_1606	5.18e-123	400.0	COG2945@1|root,COG2945@2|Bacteria,2GP8G@201174|Actinobacteria,4EXMY@85014|Glycomycetales	201174|Actinobacteria	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_6
SRR25158390_k127_1270155_3	1137268.AZXF01000011_gene3655	3.628e-133	433.0	COG3221@1|root,COG3221@2|Bacteria,2I7EX@201174|Actinobacteria	201174|Actinobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158390_k127_1270155_6	1137268.AZXF01000011_gene3654	6.392e-121	393.0	COG3638@1|root,COG3638@2|Bacteria,2I2J9@201174|Actinobacteria	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_1270155_13	1313172.YM304_34900	3.958e-77	279.0	COG3639@1|root,COG3639@2|Bacteria,2IAPI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type phosphate phosphonate transport system permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158390_k127_1270155_10	1137268.AZXF01000011_gene3652	1.438e-98	345.0	COG3639@1|root,COG3639@2|Bacteria,2IAPI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type phosphate phosphonate transport system permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158390_k127_1270155_11	1179773.BN6_27320	4.002e-94	319.0	COG2755@1|root,COG2755@2|Bacteria,2GKSW@201174|Actinobacteria,4DZ4Q@85010|Pseudonocardiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
SRR25158390_k127_1270155_17	1120950.KB892745_gene2908	9.103e-28	117.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158390_k127_1270155_1	66897.DJ64_29650	0.0	1034.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158390_k127_1270155_12	1394178.AWOO02000103_gene5701	1.165e-90	322.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4EGK7@85012|Streptosporangiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158390_k127_1270155_4	1123322.KB904669_gene3707	4.95e-126	414.0	COG0303@1|root,COG0303@2|Bacteria,2GP1B@201174|Actinobacteria	201174|Actinobacteria	H	molybdopterin	moaA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158390_k127_1270155_18	1169161.KB897718_gene3228	5.744e-22	96.0	COG0746@1|root,COG0746@2|Bacteria,2GJVE@201174|Actinobacteria	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158390_k127_1270155_15	1214101.BN159_4405	4.71e-46	172.0	COG0746@1|root,COG0746@2|Bacteria,2GJVE@201174|Actinobacteria	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158390_k127_1270155_9	269800.Tfu_2399	1.037e-105	354.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4EFJ5@85012|Streptosporangiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158390_k127_1270155_8	1380346.JNIH01000045_gene4824	7.005e-117	379.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158390_k127_1270155_7	67281.JNZZ01000039_gene1355	2.89e-117	393.0	COG0477@1|root,COG0477@2|Bacteria,2GJ9D@201174|Actinobacteria,417G0@629295|Streptomyces griseus group	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158390_k127_1270155_14	1120950.KB892805_gene1494	2.101e-52	197.0	COG0640@1|root,COG0640@2|Bacteria,2IQKG@201174|Actinobacteria,4DRR7@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_1270155_2	293826.Amet_0580	6.647e-150	489.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,36DFC@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SRR25158390_k127_1270155_0	58123.JOFJ01000014_gene5098	0.0	1424.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158390_k127_1270155_16	390989.JOEG01000003_gene4552	4.71e-46	172.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_1274672_1	526225.Gobs_3389	3.521e-72	247.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4EVPF@85013|Frankiales	201174|Actinobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158390_k127_1274672_0	675635.Psed_1764	7.844e-112	386.0	COG2508@1|root,COG2508@2|Bacteria,2GKTX@201174|Actinobacteria,4DZ79@85010|Pseudonocardiales	201174|Actinobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
SRR25158390_k127_1274672_4	1500890.JQNL01000001_gene3419	6.034e-22	100.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria,1XBZV@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
SRR25158390_k127_1274672_3	675635.Psed_1766	1.596e-29	117.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,4DXWX@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR25158390_k127_1285492_0	926554.KI912671_gene275	5.109e-99	338.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta
SRR25158390_k127_1285492_1	1283299.AUKG01000004_gene1085	5.844e-28	115.0	arCOG11477@1|root,32TJG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158390_k127_1285492_2	1461694.ATO9_22535	6.027e-14	73.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_1302924_1	479434.Sthe_0114	2.05e-20	102.0	COG0785@1|root,COG0785@2|Bacteria,2GA3F@200795|Chloroflexi,27YC0@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
SRR25158390_k127_1302924_2	1157490.EL26_18615	3.046e-20	97.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,27A30@186823|Alicyclobacillaceae	91061|Bacilli	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158390_k127_1302924_0	196162.Noca_2079	2.165e-55	198.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_1303039_1	1238186.AOCN01000007_gene590	1.158e-63	225.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria,4FQ9W@85023|Microbacteriaceae	201174|Actinobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1303039_0	1386089.N865_10190	2.445e-155	502.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4FEEH@85021|Intrasporangiaceae	201174|Actinobacteria	E	Aminotransferase	dapC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv0858c	Aminotran_1_2
SRR25158390_k127_1317501_1	926560.KE387023_gene2478	3.457e-41	153.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1317501_0	1380347.JNII01000006_gene1214	2.907e-130	424.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4ES5P@85013|Frankiales	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158390_k127_1317501_2	1304865.JAGF01000001_gene2867	2.571e-26	110.0	COG3360@1|root,COG3360@2|Bacteria,2HY46@201174|Actinobacteria,4F2YC@85016|Cellulomonadaceae	201174|Actinobacteria	S	Dodecin	-	-	-	-	-	-	-	-	-	-	-	-	Dodecin
SRR25158390_k127_1317501_3	1380356.JNIK01000021_gene4519	0.0008308	50.0	2DD1M@1|root,2ZG5Q@2|Bacteria,2GY83@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1321957_15	477641.MODMU_2871	2.668e-35	142.0	28JPA@1|root,2Z9FC@2|Bacteria	2|Bacteria	-	-	cmcJ	-	-	ko:K18063	-	M00673	-	-	ko00000,ko00002	-	-	-	-
SRR25158390_k127_1321957_14	1463825.JNXC01000015_gene7540	7.399e-43	168.0	COG4911@1|root,COG4911@2|Bacteria,2IMEK@201174|Actinobacteria,4E4F1@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158390_k127_1321957_11	1380354.JIAN01000005_gene2567	6.324e-62	220.0	COG2606@1|root,COG2606@2|Bacteria,2IIIW@201174|Actinobacteria,4F1D0@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158390_k127_1321957_13	1906.SFRA_28375	7.148e-46	173.0	COG1704@1|root,COG1704@2|Bacteria,2GK54@201174|Actinobacteria	201174|Actinobacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LemA
SRR25158390_k127_1321957_4	1120950.KB892708_gene4267	6.786e-155	499.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4DNV1@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158390_k127_1321957_6	67352.JODS01000020_gene4012	3.137e-92	315.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria	201174|Actinobacteria	M	Lipid A biosynthesis	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158390_k127_1321957_7	367299.JOEE01000008_gene523	9.365e-72	247.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4FF7D@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_1321957_0	1120950.KB892708_gene4264	0.0	1015.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4DNXI@85009|Propionibacteriales	201174|Actinobacteria	J	Elongation factor G, domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158390_k127_1321957_9	1380356.JNIK01000011_gene1585	8.198e-66	236.0	COG5340@1|root,COG5340@2|Bacteria,2II40@201174|Actinobacteria,4ET1K@85013|Frankiales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_1321957_8	1127134.NOCYR_3609	1.649e-69	241.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4FVD6@85025|Nocardiaceae	201174|Actinobacteria	FG	HIT domain	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158390_k127_1321957_1	471852.Tcur_2095	9.053e-313	972.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4EG5V@85012|Streptosporangiales	201174|Actinobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158390_k127_1321957_2	1246995.AFR_14280	6.925e-165	526.0	COG1063@1|root,COG1063@2|Bacteria,2GKFG@201174|Actinobacteria,4D8DN@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
SRR25158390_k127_1321957_3	1150864.MILUP08_42122	3.989e-160	512.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4D9MN@85008|Micromonosporales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158390_k127_1321957_5	479432.Sros_1300	2.003e-92	309.0	COG1028@1|root,COG1028@2|Bacteria,2GJ0E@201174|Actinobacteria,4EJ2C@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_1321957_10	405948.SACE_3686	1.35e-62	220.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4E62J@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158390_k127_1321957_12	110319.CF8_3665	9.002e-56	202.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4DN62@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1321957_16	471853.Bcav_1061	2.056e-16	84.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_1322730_1	136273.GY22_02990	1.824e-155	496.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,1W80Z@1268|Micrococcaceae	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158390_k127_1322730_5	994479.GL877879_gene5814	8.227e-62	236.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4DXF7@85010|Pseudonocardiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158390_k127_1322730_0	1048339.KB913029_gene4521	0.0	1227.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4ES9K@85013|Frankiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158390_k127_1322730_6	1003195.SCAT_1137	8.556e-50	181.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_1322730_2	1123024.AUII01000006_gene4530	1.333e-108	368.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4DYKY@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
SRR25158390_k127_1322730_4	358823.DF19_13310	2.538e-102	344.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1322730_3	1172185.KB911518_gene2809	1.276e-102	340.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4G8R8@85025|Nocardiaceae	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_1334388_3	1177594.MIC448_730006	1.832e-68	237.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,4FSGE@85023|Microbacteriaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1334388_0	477641.MODMU_2927	9.416e-146	471.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4EWAG@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158390_k127_1334388_2	1380393.JHVP01000004_gene556	6.892e-90	316.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4ESBV@85013|Frankiales	201174|Actinobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, B subunit	scoB	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2503c	CoA_trans
SRR25158390_k127_1334388_1	477641.MODMU_2925	3.675e-115	377.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4ETU3@85013|Frankiales	201174|Actinobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158390_k127_1344923_1	1380356.JNIK01000014_gene3095	3.981e-46	174.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4ESQZ@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158390_k127_1344923_4	452652.KSE_39360	2.22e-10	62.0	2EHSF@1|root,33BI6@2|Bacteria,2GRN8@201174|Actinobacteria,2M3TC@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1344923_3	1122132.AQYH01000020_gene130	5.25e-12	70.0	2DNGD@1|root,32XCZ@2|Bacteria,1RJW1@1224|Proteobacteria,2U9RF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1344923_2	471852.Tcur_0802	2.082e-32	136.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4EKIY@85012|Streptosporangiales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_1344923_0	1033730.CAHG01000010_gene2528	9.913e-200	629.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4DN8F@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_1347317_1	1340434.AXVA01000004_gene2614	0.0003371	47.0	COG3794@1|root,COG3794@2|Bacteria,1VQGS@1239|Firmicutes,4HXFN@91061|Bacilli,1ZH4H@1386|Bacillus	91061|Bacilli	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158390_k127_1374872_12	1137269.AZWL01000010_gene5122	1.313e-30	124.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158390_k127_1374872_5	479435.Kfla_5504	8.537e-89	304.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4DNXW@85009|Propionibacteriales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	chcB	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158390_k127_1374872_4	479432.Sros_8420	1.432e-90	306.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4EHQ8@85012|Streptosporangiales	201174|Actinobacteria	K	PaaX-like protein	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158390_k127_1374872_15	222534.KB893670_gene3725	2.189e-25	105.0	2E39N@1|root,32Y97@2|Bacteria,2GQFF@201174|Actinobacteria,4ET8T@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3117
SRR25158390_k127_1374872_2	58123.JOFJ01000015_gene4524	3.336e-139	458.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4EFVT@85012|Streptosporangiales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158390_k127_1374872_6	110319.CF8_0874	1.177e-86	291.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4DNEI@85009|Propionibacteriales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
SRR25158390_k127_1374872_7	1120936.KB907225_gene2744	7.675e-86	294.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4EHBC@85012|Streptosporangiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1374872_16	1120936.KB907225_gene2743	4.248e-20	98.0	COG5662@1|root,COG5662@2|Bacteria,2GKPI@201174|Actinobacteria,4EJRI@85012|Streptosporangiales	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_1374872_10	1120950.KB892823_gene489	5.316e-48	188.0	COG3026@1|root,COG3026@2|Bacteria,2IRR9@201174|Actinobacteria,4DSGE@85009|Propionibacteriales	201174|Actinobacteria	T	antisigma factor binding	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB
SRR25158390_k127_1374872_3	926564.KI911760_gene4820	3.911e-92	318.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4F40H@85017|Promicromonosporaceae	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_1374872_19	1122138.AQUZ01000003_gene572	1.113e-11	70.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,4DRKC@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158390_k127_1374872_1	1048339.KB913029_gene2894	1.269e-162	519.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4ERFN@85013|Frankiales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158390_k127_1374872_11	298655.KI912266_gene1966	1.968e-41	158.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4ET44@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158390_k127_1374872_8	1464048.JNZS01000047_gene681	8.169e-64	235.0	COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4D9JP@85008|Micromonosporales	201174|Actinobacteria	P	cobalt transport	ykoC	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158390_k127_1374872_0	369723.Strop_3443	2.238e-182	588.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4D9CY@85008|Micromonosporales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
SRR25158390_k127_1374872_9	1236902.ANAS01000041_gene4362	7.275e-59	213.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria	201174|Actinobacteria	S	membrane	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
SRR25158390_k127_1374872_17	1150864.MILUP08_44861	9.382e-13	79.0	2EDJR@1|root,337FI@2|Bacteria,2GIRI@201174|Actinobacteria,4DIZB@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1374872_13	471852.Tcur_1191	2.842e-30	126.0	2E6WZ@1|root,331GF@2|Bacteria,2IFC6@201174|Actinobacteria,4EK7D@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1374872_14	981369.JQMJ01000004_gene447	3.384e-26	116.0	COG0204@1|root,COG0204@2|Bacteria,2IBCT@201174|Actinobacteria,2NIF5@228398|Streptacidiphilus	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158390_k127_138231_6	634956.Geoth_0902	6.282e-80	271.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1WEAW@129337|Geobacillus	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_138231_1	211114.JOEF01000048_gene5362	1.014e-165	526.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DYMT@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158390_k127_138231_0	1122611.KB903961_gene4372	1.549e-229	714.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4EFHD@85012|Streptosporangiales	201174|Actinobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158390_k127_138231_5	1137271.AZUM01000008_gene2061	9.617e-94	331.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4E015@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158390_k127_138231_4	749414.SBI_04361	4.496e-127	414.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158390_k127_138231_3	1122138.AQUZ01000084_gene8782	3.549e-142	465.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4DPDV@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_138231_2	1123024.AUII01000003_gene3619	1.07e-143	463.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4E1GX@85010|Pseudonocardiales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158390_k127_138231_7	1120950.KB892760_gene5749	7.662e-32	130.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria,4DRBR@85009|Propionibacteriales	201174|Actinobacteria	J	LigT like Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158390_k127_1391573_0	405948.SACE_2334	6.053e-131	422.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4E9CU@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	tnp3508a	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR25158390_k127_1391573_1	35754.JNYJ01000009_gene1873	3.342e-118	389.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DB3M@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_1391573_3	1120950.KB892717_gene2440	8.529e-88	311.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4DPV3@85009|Propionibacteriales	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158390_k127_1391573_4	1122609.AUGT01000020_gene1100	3.125e-05	52.0	29VZC@1|root,30HHK@2|Bacteria,2GY8K@201174|Actinobacteria,4DSUP@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1391573_2	1095767.CAHD01000132_gene1259	7.836e-114	373.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria,4F0T6@85016|Cellulomonadaceae	201174|Actinobacteria	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	ApbA,ApbA_C,Rhodanese
SRR25158390_k127_1391573_5	1048339.KB913029_gene3828	0.0002488	47.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4ETG1@85013|Frankiales	201174|Actinobacteria	GK	PFAM ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158390_k127_1397222_1	1120950.KB892801_gene1782	5.645e-185	587.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4DNRS@85009|Propionibacteriales	201174|Actinobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_1397222_4	1463881.KL591016_gene5426	2.383e-90	302.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_1397222_8	479435.Kfla_6328	3.734e-46	173.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4DRF7@85009|Propionibacteriales	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158390_k127_1397222_3	1352941.M877_20790	5.753e-101	334.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158390_k127_1397222_2	1120950.KB892801_gene1786	8.082e-160	531.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4DN12@85009|Propionibacteriales	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158390_k127_1397222_5	1048339.KB913029_gene2342	8.828e-76	265.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4ESE9@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158390_k127_1397222_6	593907.Celgi_0795	5.374e-69	239.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4F0Q3@85016|Cellulomonadaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158390_k127_1397222_7	1123251.ATWM01000006_gene2199	3.859e-55	196.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4FGN6@85021|Intrasporangiaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158390_k127_1397222_0	1048339.KB913029_gene2735	3.331e-279	866.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4ES8S@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158390_k127_1403689_16	457429.ABJI02000741_gene338	1.675e-09	63.0	COG0654@1|root,COG2072@1|root,COG0654@2|Bacteria,COG2072@2|Bacteria,2GK95@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	arsO	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158390_k127_1403689_3	1122138.AQUZ01000005_gene2484	2.087e-113	372.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4DPZJ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_1403689_2	1122138.AQUZ01000019_gene8125	9.801e-130	432.0	COG2128@1|root,COG2128@2|Bacteria,2IEYG@201174|Actinobacteria,4DTIZ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158390_k127_1403689_12	675635.Psed_1305	1.262e-49	179.0	2CIGV@1|root,32S80@2|Bacteria,2IT9G@201174|Actinobacteria,4EBCN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1403689_4	1123319.AUBE01000007_gene3451	1.81e-89	324.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1403689_0	1136417.AZWE01000005_gene4550	6.37e-290	897.0	COG1964@1|root,COG1964@2|Bacteria,2I9RQ@201174|Actinobacteria,4DJ9M@85008|Micromonosporales	201174|Actinobacteria	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_11,Radical_SAM
SRR25158390_k127_1403689_1	1451261.AS96_07715	3.82e-138	448.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4FM9J@85023|Microbacteriaceae	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_1403689_11	1451261.AS96_14850	1.109e-49	179.0	COG0640@1|root,COG0640@2|Bacteria,2IM0G@201174|Actinobacteria,4FPIY@85023|Microbacteriaceae	201174|Actinobacteria	K	arsR family transcriptional regulator	kmtR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1403689_8	1120936.KB907217_gene3579	3.598e-60	218.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4EG9U@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158390_k127_1403689_19	402881.Plav_0589	6.165e-06	53.0	2BW2J@1|root,331CU@2|Bacteria,1N7GK@1224|Proteobacteria,2U7KS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1403689_18	1317122.ATO12_15025	4.914e-07	61.0	COG2867@1|root,COG2867@2|Bacteria,4PAKD@976|Bacteroidetes,1IHSE@117743|Flavobacteriia,2YJ70@290174|Aquimarina	976|Bacteroidetes	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_1403689_15	1229780.BN381_10080	7.169e-36	143.0	2EEE7@1|root,33888@2|Bacteria,2IMP5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1403689_17	477974.Daud_0431	3.532e-09	65.0	COG1714@1|root,COG1714@2|Bacteria,1VATS@1239|Firmicutes,24TP2@186801|Clostridia,26383@186807|Peptococcaceae	186801|Clostridia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_1403689_7	1121272.KB903283_gene5278	2.5e-83	281.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4DD8E@85008|Micromonosporales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_1403689_10	1120950.KB892720_gene1829	3.993e-58	208.0	COG1309@1|root,COG1309@2|Bacteria,2IPAX@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_1403689_5	67332.FM21_13570	1.439e-87	297.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_1403689_9	67332.FM21_13530	1.634e-59	218.0	2DKVQ@1|root,30HQN@2|Bacteria,2GPA0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
SRR25158390_k127_1403689_6	1050202.KB913024_gene3603	1.502e-85	289.0	COG0664@1|root,COG0664@2|Bacteria,2IB1J@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21884	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_1403689_14	675635.Psed_1309	8.896e-39	150.0	2EJIE@1|root,33D9B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1403689_13	196162.Noca_2079	5.965e-48	175.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_1408325_5	290400.Jann_3792	3.34e-104	351.0	28MZG@1|root,2ZB66@2|Bacteria,1R6ZF@1224|Proteobacteria,2U3DX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_1408325_6	1449355.JQNR01000005_gene5020	8.747e-68	258.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1408325_1	1120950.KB892763_gene5541	3.259e-198	630.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4DPYX@85009|Propionibacteriales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1408325_7	479433.Caci_0663	3.063e-15	89.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_1408325_2	1120950.KB892763_gene5544	9.167e-166	531.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DN8T@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158390_k127_1408325_0	457429.ABJI02000758_gene4964	3.838e-315	985.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349,ko:K17641	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158390_k127_1408325_3	33876.JNXY01000026_gene3457	6.834e-153	498.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DA7N@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional	bxlR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_1408325_4	1380354.JIAN01000009_gene3867	3.27e-108	359.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4F25R@85016|Cellulomonadaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_14100_6	263358.VAB18032_22340	3.531e-31	131.0	COG2508@1|root,COG2508@2|Bacteria,2GKV3@201174|Actinobacteria,4DBJB@85008|Micromonosporales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158390_k127_14100_4	479432.Sros_5995	7.989e-68	243.0	COG1802@1|root,COG1802@2|Bacteria,2GMJX@201174|Actinobacteria,4EH5I@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_14100_0	1120950.KB892802_gene1422	9.38e-166	545.0	COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria,4DNIG@85009|Propionibacteriales	201174|Actinobacteria	E	Proline racemase	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158390_k127_14100_2	1463821.JOGR01000004_gene2493	1.571e-133	432.0	COG0329@1|root,COG0329@2|Bacteria,2I30F@201174|Actinobacteria	201174|Actinobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158390_k127_14100_3	58344.JOEL01000001_gene451	1.589e-128	428.0	COG0446@1|root,COG0446@2|Bacteria,2GJM6@201174|Actinobacteria	201174|Actinobacteria	E	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
SRR25158390_k127_14100_5	1120950.KB892802_gene1425	2.641e-34	133.0	COG3383@1|root,COG3383@2|Bacteria,2GSHP@201174|Actinobacteria,4DSUY@85009|Propionibacteriales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
SRR25158390_k127_14100_1	358823.DF19_06220	6.354e-150	483.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158390_k127_1450211_1	298653.Franean1_7160	1.318e-89	304.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4EUN5@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158390_k127_1450211_0	365528.KB891230_gene1881	1.828e-287	897.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU1V@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_1462641_3	526225.Gobs_0311	3.849e-107	352.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4ETSF@85013|Frankiales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_1462641_2	526225.Gobs_0312	3.01e-120	398.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4ESQD@85013|Frankiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_1462641_1	526225.Gobs_0313	6.011e-121	397.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4EUEK@85013|Frankiales	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1462641_0	266940.Krad_3859	3.686e-145	475.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1462641_4	1869.MB27_22940	7.161e-44	172.0	COG5340@1|root,COG5340@2|Bacteria,2ICWZ@201174|Actinobacteria,4DD3H@85008|Micromonosporales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158390_k127_1463493_7	1445613.JALM01000020_gene4655	2.822e-14	74.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DZMS@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103,1.1.1.380	ko:K00060,ko:K08322	ko00040,ko00260,ko01100,map00040,map00260,map01100	-	R01465,R10848	RC00085,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_1463493_10	1229780.BN381_540002	6.857e-07	53.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	GO:0005575,GO:0005576,GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_1463493_4	1150864.MILUP08_41317	3.732e-63	218.0	COG1487@1|root,COG1487@2|Bacteria,2IRPF@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_1463493_5	1150864.MILUP08_41318	3.887e-28	116.0	2BEJR@1|root,328B3@2|Bacteria,2HE3C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158390_k127_1463493_0	479435.Kfla_3615	1.648e-289	902.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DP9H@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_1463493_3	1121019.AUMN01000008_gene3240	3.538e-87	305.0	COG0477@1|root,COG2814@2|Bacteria,2I2JA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1463493_6	211114.JOEF01000019_gene466	2.878e-26	113.0	COG0346@1|root,COG0346@2|Bacteria,2IP65@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1463493_2	103733.JNYO01000024_gene9155	1.1e-95	335.0	COG2304@1|root,COG2304@2|Bacteria,2GUB3@201174|Actinobacteria,4E1CP@85010|Pseudonocardiales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,VWA
SRR25158390_k127_1463493_8	656024.FsymDg_0379	4.386e-12	66.0	COG2402@1|root,COG2402@2|Bacteria,2IFKB@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_1463493_1	1120950.KB892708_gene4418	3.056e-165	527.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DNHC@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_1488919_2	1961.JOAK01000048_gene5787	6.467e-116	387.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158390_k127_1488919_6	1382306.JNIM01000001_gene3599	5.144e-20	93.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1488919_1	1304275.C41B8_18181	3.027e-194	622.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRR25158390_k127_1488919_0	525909.Afer_1020	0.0	1503.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158390_k127_1488919_5	1304275.C41B8_18191	2.781e-35	147.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	dmsD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
SRR25158390_k127_1488919_4	156889.Mmc1_3745	8.129e-50	183.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2U6FZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158390_k127_1488919_7	1273538.G159_14385	9.158e-19	96.0	COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,26F3H@186818|Planococcaceae	91061|Bacilli	OP	Belongs to the sulfur carrier protein TusA family	yrkF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,TusA
SRR25158390_k127_1488919_3	1463821.JOGR01000001_gene1352	1.677e-57	201.0	COG3631@1|root,COG3631@2|Bacteria,2IM0Y@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158390_k127_1488919_8	222534.KB893672_gene3052	4.449e-10	60.0	COG1733@1|root,COG1733@2|Bacteria,2IJCU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_1491821_1	33876.JNXY01000005_gene8798	5.618e-206	647.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4DBBT@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158390_k127_1491821_5	1304865.JAGF01000001_gene2887	7.95e-100	333.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4F0NV@85016|Cellulomonadaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158390_k127_1491821_2	1048339.KB913029_gene4786	7.597e-131	426.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4ERUY@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158390_k127_1491821_3	479435.Kfla_2457	3.175e-122	406.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4DPI0@85009|Propionibacteriales	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158390_k127_1491821_8	1352941.M877_29235	1.198e-83	284.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	mntB	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158390_k127_1491821_6	1033730.CAHG01000013_gene1320	3.592e-85	293.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4DNM9@85009|Propionibacteriales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	scbA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158390_k127_1491821_7	2074.JNYD01000007_gene2100	3.702e-85	297.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DY5S@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YibE F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158390_k127_1491821_0	1463821.JOGR01000007_gene37	1.613e-236	737.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4EXQQ@85014|Glycomycetales	201174|Actinobacteria	J	tRNA synthetase class II core domain (G, H, P, S and T)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158390_k127_1491821_4	1122622.ATWJ01000001_gene2463	1.685e-107	361.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria,4FGJ4@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1491821_10	58123.JOFJ01000033_gene60	5.267e-41	161.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4EKKN@85012|Streptosporangiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158390_k127_1491821_9	58123.JOFJ01000033_gene59	1.528e-78	272.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4ER5R@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_1498191_4	555079.Toce_2076	1.586e-34	139.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_1498191_0	1449353.JQMQ01000005_gene4992	4.201e-185	595.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,2NGHZ@228398|Streptacidiphilus	201174|Actinobacteria	F	Amidohydrolase family	atzB	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_1498191_2	37919.EP51_18900	1.428e-39	155.0	COG3195@1|root,COG3195@2|Bacteria,2GKIP@201174|Actinobacteria,4G2NT@85025|Nocardiaceae	201174|Actinobacteria	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox,Transthyretin
SRR25158390_k127_1498191_3	208439.AJAP_09700	1.291e-35	139.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4E5V4@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158390_k127_1498191_1	675635.Psed_1766	1.75e-58	207.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,4DXWX@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR25158390_k127_1499658_0	644283.Micau_4485	2.081e-216	679.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4DAJQ@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158390_k127_1500006_6	557599.MKAN_25980	1.74e-55	199.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,23A6Z@1762|Mycobacteriaceae	201174|Actinobacteria	C	ferredoxin	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_1500006_8	1123024.AUII01000003_gene3441	2.123e-37	146.0	2E3NN@1|root,32YKS@2|Bacteria,2GUAX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1500006_3	1123024.AUII01000046_gene3925	1.253e-114	382.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4E0F4@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitrate reductase gamma subunit	narI	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	1.7.5.1	ko:K00370,ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iNJ661.Rv1164	Nitrate_red_gam
SRR25158390_k127_1500006_7	1146883.BLASA_4871	1.012e-50	192.0	COG2180@1|root,COG2180@2|Bacteria,2IAQV@201174|Actinobacteria,4ESU6@85013|Frankiales	201174|Actinobacteria	C	Nitrate reductase, delta subunit	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
SRR25158390_k127_1500006_1	1278078.G419_13226	2.474e-289	905.0	COG1140@1|root,COG1140@2|Bacteria,2GJ8P@201174|Actinobacteria,4FUZU@85025|Nocardiaceae	201174|Actinobacteria	C	Nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
SRR25158390_k127_1500006_0	2074.JNYD01000002_gene5542	0.0	2072.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4DZ13@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008940,GO:0009056,GO:0009628,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016491,GO:0016661,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036293,GO:0036294,GO:0042126,GO:0042128,GO:0042221,GO:0042493,GO:0043436,GO:0043602,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070482,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071453,GO:0071704,GO:0071731,GO:0071732,GO:0071941,GO:0071944,GO:0097366,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:2001057	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
SRR25158390_k127_1500006_2	479432.Sros_5440	1.945e-142	467.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4EGQH@85012|Streptosporangiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,Sugar_tr
SRR25158390_k127_1500006_5	1146883.BLASA_4868	1.197e-87	305.0	COG1275@1|root,COG1275@2|Bacteria,2GK0D@201174|Actinobacteria,4ETN8@85013|Frankiales	201174|Actinobacteria	P	C4-dicarboxylate transporter malic acid	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
SRR25158390_k127_1500006_4	1386089.N865_14270	5.474e-91	311.0	arCOG10456@1|root,2ZA6T@2|Bacteria,2IT80@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1514497_1	1120950.KB892746_gene3604	0.0	1107.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4DP2S@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158390_k127_1514497_19	743718.Isova_0377	6.74e-35	145.0	COG5340@1|root,COG5340@2|Bacteria,2ICWZ@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158390_k127_1514497_12	471852.Tcur_4326	1.394e-65	226.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4EJ9N@85012|Streptosporangiales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158390_k127_1514497_8	479433.Caci_0922	2.416e-86	288.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158390_k127_1514497_0	1048339.KB913029_gene2747	0.0	1175.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4ERUQ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158390_k127_1514497_2	188626.HMPREF0321_1179	6.912e-231	717.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,1ZVEV@145357|Dermacoccaceae	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158390_k127_1514497_14	68570.DC74_3825	1.398e-60	212.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158390_k127_1514497_5	500153.JOEK01000005_gene2106	9.499e-101	332.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158390_k127_1514497_7	1120950.KB892746_gene3611	3.589e-91	308.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4DN59@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158390_k127_1514497_16	1120954.ATXE01000003_gene354	2.176e-45	168.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4DR9N@85009|Propionibacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158390_k127_1514497_3	1048339.KB913029_gene2753	2.753e-152	488.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4ES62@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158390_k127_1514497_15	1048339.KB913029_gene2754	2.1e-51	184.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4ESWC@85013|Frankiales	201174|Actinobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158390_k127_1514497_17	33876.JNXY01000022_gene4529	4.084e-43	160.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4DD68@85008|Micromonosporales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158390_k127_1514497_4	1184607.AUCHE_08_03500	1.139e-113	383.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4F6F5@85018|Dermatophilaceae	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158390_k127_1514497_10	1120950.KB892746_gene3617	1.393e-72	255.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4DQ7S@85009|Propionibacteriales	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158390_k127_1514497_22	935839.JAGJ01000006_gene3314	9.379e-25	105.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4F4T2@85017|Promicromonosporaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158390_k127_1514497_20	269800.Tfu_2637	1.324e-33	134.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4EK0X@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158390_k127_1514497_11	1048339.KB913029_gene2760	4.783e-69	235.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4ESIV@85013|Frankiales	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158390_k127_1514497_18	68570.DC74_3813	7.752e-42	160.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158390_k127_1514497_6	1123320.KB889574_gene5562	1.084e-98	324.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158390_k127_1514497_21	1089455.MOPEL_098_00380	1.108e-31	124.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4F757@85018|Dermatophilaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158390_k127_1514497_13	662755.CRES_1859	3.813e-61	214.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,22MWH@1653|Corynebacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158390_k127_1514497_9	1288083.AUKR01000012_gene674	9.602e-82	276.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158390_k127_1514497_23	1048339.KB913029_gene2766	6.792e-06	48.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4ESW2@85013|Frankiales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158390_k127_1518934_0	405948.SACE_0537	8.925e-265	823.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DZTZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_1518934_2	1380356.JNIK01000019_gene377	8.416e-72	248.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4ESSY@85013|Frankiales	201174|Actinobacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158390_k127_1518934_3	471852.Tcur_2977	4.321e-58	207.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4EJ8B@85012|Streptosporangiales	201174|Actinobacteria	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158390_k127_1518934_1	28444.JODQ01000001_gene2176	1.957e-142	458.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4EIDG@85012|Streptosporangiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158390_k127_1522223_0	1122138.AQUZ01000047_gene80	0.0	1372.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DNWF@85009|Propionibacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158390_k127_1522223_6	471852.Tcur_1021	1.49e-92	321.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2GMUK@201174|Actinobacteria,4EHNK@85012|Streptosporangiales	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158390_k127_1522223_1	35754.JNYJ01000007_gene2695	8.704e-216	678.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4DAUT@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158390_k127_1522223_3	1048339.KB913029_gene4510	8.557e-154	498.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4ERIE@85013|Frankiales	201174|Actinobacteria	EH	Sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158390_k127_1522223_9	1043493.BBLU01000007_gene36	4.462e-86	292.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria	201174|Actinobacteria	P	inositol monophosphatase	cysQ	GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0008934,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019637,GO:0019693,GO:0030145,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050308,GO:0050427,GO:0050897,GO:0052745,GO:0052834,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158390_k127_1522223_5	1313172.YM304_29130	4.264e-110	367.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SRR25158390_k127_1522223_8	1313172.YM304_29140	1.447e-88	305.0	COG4597@1|root,COG4597@2|Bacteria	2|Bacteria	P	amino acid transport	bgtB	-	-	ko:K09970,ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158390_k127_1522223_10	383372.Rcas_1456	1.088e-84	296.0	COG0765@1|root,COG0765@2|Bacteria,2G845@200795|Chloroflexi,376Y4@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158390_k127_1522223_4	1313172.YM304_29160	4.625e-121	394.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CP57@84992|Acidimicrobiia	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10041	ko02010,map02010	M00228,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
SRR25158390_k127_1522223_12	543632.JOJL01000007_gene5509	6.944e-10	63.0	COG3550@1|root,COG3550@2|Bacteria,2IA5Z@201174|Actinobacteria	201174|Actinobacteria	S	domain protein	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
SRR25158390_k127_1522223_13	479435.Kfla_0120	4.02e-05	53.0	COG1708@1|root,COG1708@2|Bacteria,2GUWM@201174|Actinobacteria,4DVAU@85009|Propionibacteriales	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158390_k127_1522223_7	469383.Cwoe_1255	1.315e-89	316.0	COG0457@1|root,COG0457@2|Bacteria	469383.Cwoe_1255|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1522223_11	530564.Psta_1246	9.535e-43	173.0	COG3391@1|root,COG3391@2|Bacteria,2J1IA@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1525288_5	1121926.AXWO01000017_gene3050	2.194e-43	160.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EXPJ@85014|Glycomycetales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_1525288_0	1122611.KB903985_gene3701	7.423e-239	754.0	COG1472@1|root,COG5520@1|root,COG1472@2|Bacteria,COG5520@2|Bacteria,2GJ5H@201174|Actinobacteria,4EH72@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 C-terminal domain	celD	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_2,Glyco_hydro_3,Glyco_hydro_3_C,fn3
SRR25158390_k127_1525288_4	1380356.JNIK01000011_gene1585	1.972e-68	245.0	COG5340@1|root,COG5340@2|Bacteria,2II40@201174|Actinobacteria,4ET1K@85013|Frankiales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_1525288_2	479432.Sros_0993	1.295e-97	329.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria,4EH5Z@85012|Streptosporangiales	201174|Actinobacteria	P	Cobalt uptake substrate-specific transmembrane region	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158390_k127_1525288_3	1169161.KB897724_gene4928	3.756e-82	294.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt ABC transporter	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158390_k127_1525288_1	1120936.KB907209_gene1754	9.555e-120	395.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4EFVM@85012|Streptosporangiales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158390_k127_1525288_6	479435.Kfla_1858	2.417e-06	53.0	2DYK7@1|root,34A68@2|Bacteria,2HZGV@201174|Actinobacteria,4DSRQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158390_k127_1556863_2	414996.IL38_09640	6.899e-125	409.0	COG1226@1|root,COG1226@2|Bacteria,2I28H@201174|Actinobacteria,40839@622450|Actinopolysporales	201174|Actinobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
SRR25158390_k127_1556863_0	1464048.JNZS01000027_gene1893	1.377e-213	672.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4D9RA@85008|Micromonosporales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0055114	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
SRR25158390_k127_1556863_4	1464048.JNZS01000027_gene1894	4.588e-95	321.0	COG4221@1|root,COG4221@2|Bacteria,2GKJ8@201174|Actinobacteria,4DAZ6@85008|Micromonosporales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_1556863_5	1121272.KB903291_gene3372	2.574e-77	268.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4DBFD@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_1556863_6	367299.JOEE01000001_gene1793	5.13e-45	166.0	COG5450@1|root,32SQA@2|Bacteria,2IKJX@201174|Actinobacteria,4FH03@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcription regulator of the Arc MetJ class	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1556863_7	1146883.BLASA_3298	6.845e-17	88.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
SRR25158390_k127_1556863_1	110319.CF8_0123	6.383e-164	530.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4DN3N@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
SRR25158390_k127_1556863_3	1120949.KB903294_gene4404	4.848e-123	415.0	COG2304@1|root,COG2304@2|Bacteria,2H3JW@201174|Actinobacteria,4DHZC@85008|Micromonosporales	201174|Actinobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1556863_8	435830.HMPREF0045_00267	0.0002847	51.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4D4DF@85005|Actinomycetales	201174|Actinobacteria	D	DivIVA domain protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158390_k127_156887_0	1353531.AZNX01000009_gene984	1.259e-63	234.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158390_k127_156887_1	219305.MCAG_01014	9.59e-14	74.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DB80@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_1622252_5	1523503.JPMY01000017_gene2899	3.323e-94	318.0	COG2207@1|root,COG2207@2|Bacteria,1R5D8@1224|Proteobacteria,1RYEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
SRR25158390_k127_1622252_0	1390370.O203_11910	3.629e-204	643.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RY92@1236|Gammaproteobacteria,1YEAS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	FMO-like,Pyr_redox_3
SRR25158390_k127_1622252_4	1288826.MSNKSG1_15022	7.583e-120	402.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,46A32@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
SRR25158390_k127_1622252_3	1288826.MSNKSG1_15017	2.253e-125	424.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158390_k127_1622252_9	1283287.KB822575_gene169	2.246e-18	98.0	2ETMT@1|root,33M5J@2|Bacteria,2IQ41@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2530
SRR25158390_k127_1622252_6	1237500.ANBA01000008_gene259	1.165e-54	202.0	COG1091@1|root,COG1091@2|Bacteria,2I0YH@201174|Actinobacteria,4EI5M@85012|Streptosporangiales	201174|Actinobacteria	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158390_k127_1622252_2	1298880.AUEV01000018_gene289	4.445e-159	506.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_1622252_1	443218.AS9A_3041	3.264e-165	536.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,233W7@1762|Mycobacteriaceae	201174|Actinobacteria	M	ABC transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158390_k127_1622252_7	1089546.AQUI01000002_gene2308	9.097e-42	159.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269,HIT
SRR25158390_k127_1622252_8	1120936.KB907208_gene582	1.405e-23	104.0	COG3225@1|root,COG3225@2|Bacteria,2GMTX@201174|Actinobacteria,4EG0S@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1623479_6	591157.SSLG_00165	4.434e-115	378.0	COG3435@1|root,COG3435@2|Bacteria,2GZST@201174|Actinobacteria	201174|Actinobacteria	Q	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_1623479_16	1380386.JIAW01000030_gene3586	5.234e-82	283.0	COG0464@1|root,COG0464@2|Bacteria,2IN7Z@201174|Actinobacteria	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158390_k127_1623479_3	1449353.JQMQ01000005_gene5573	2.366e-154	493.0	COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158390_k127_1623479_29	1116232.AHBF01000046_gene2174	3.718e-22	111.0	COG0477@1|root,COG2814@2|Bacteria,2I66X@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4
SRR25158390_k127_1623479_28	469383.Cwoe_4070	3.587e-24	118.0	COG0715@1|root,COG0715@2|Bacteria,2IJ9K@201174|Actinobacteria	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,NMT1_2
SRR25158390_k127_1623479_9	1123060.JONP01000028_gene3681	1.282e-101	346.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_1623479_15	1380386.JIAW01000030_gene3591	3.635e-86	298.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,23CXF@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158390_k127_1623479_5	1042326.AZNV01000012_gene1943	5.372e-123	418.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,4BAT1@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158390_k127_1623479_26	690585.JNNU01000010_gene823	5.763e-25	119.0	COG1840@1|root,COG1840@2|Bacteria,1R9BH@1224|Proteobacteria,2TQP7@28211|Alphaproteobacteria,4BCAC@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
SRR25158390_k127_1623479_14	1452535.JARD01000029_gene892	1.518e-90	314.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FKZV@85023|Microbacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_1623479_31	1156935.QWE_09535	1.915e-09	70.0	2A2TQ@1|root,30ZC5@2|Bacteria,1PMAC@1224|Proteobacteria,2UZXM@28211|Alphaproteobacteria,4BFTE@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1623479_21	1298880.AUEV01000011_gene2656	4.12e-65	232.0	COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158390_k127_1623479_25	312284.A20C1_03378	1.954e-29	134.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_1623479_17	257310.BB4331	4.158e-72	259.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VNG0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1623479_11	1120983.KB894572_gene3272	1.766e-95	325.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,1JQ4A@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_1623479_27	589865.DaAHT2_2664	1.012e-24	116.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MIF9@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_1623479_13	1120959.ATXF01000005_gene1260	1.545e-91	310.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4FRRP@85023|Microbacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158390_k127_1623479_20	263358.VAB18032_20650	2.896e-66	242.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158390_k127_1623479_18	1382356.JQMP01000003_gene1735	3.471e-71	247.0	COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi	200795|Chloroflexi	G	Class II Aldolase and Adducin N-terminal domain	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158390_k127_1623479_2	1449353.JQMQ01000005_gene5587	1.21e-155	497.0	2F1RH@1|root,33URM@2|Bacteria,2I842@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_1623479_19	1380386.JIAW01000030_gene3601	3.322e-69	243.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,237K0@1762|Mycobacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158390_k127_1623479_22	710685.MycrhN_3129	3.682e-53	196.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,237K0@1762|Mycobacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158390_k127_1623479_0	1463857.JOFZ01000005_gene3350	4.095e-236	734.0	COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158390_k127_1623479_30	492774.JQMB01000002_gene773	2.149e-17	89.0	2AAE0@1|root,30ZQ8@2|Bacteria,1PMNU@1224|Proteobacteria,2V08Z@28211|Alphaproteobacteria,4BJFF@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1623479_7	1122604.JONR01000001_gene1774	1.044e-114	375.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1X3R8@135614|Xanthomonadales	1236|Gammaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	-	-	-	-	-	-	-	-	-	-	-	-	Pantoate_transf
SRR25158390_k127_1623479_1	1547437.LL06_00290	2.697e-232	734.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_1623479_12	309801.trd_A0069	5.294e-93	334.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_1623479_23	309801.trd_A0776	1.225e-36	149.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	2|Bacteria	C	2Fe-2S -binding domain protein	coxS	-	1.2.5.3,1.3.99.16,1.5.99.4	ko:K03518,ko:K07302,ko:K19819	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158390_k127_1623479_24	1123229.AUBC01000008_gene524	4.994e-33	139.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JR5X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	coxM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158390_k127_1623479_8	1500257.JQNM01000014_gene2928	6.287e-114	373.0	COG0596@1|root,COG0596@2|Bacteria,1NDHC@1224|Proteobacteria,2UPRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_1623479_4	1380386.JIAW01000030_gene3591	5.613e-130	425.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,23CXF@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158390_k127_1623479_10	1380386.JIAW01000030_gene3590	1.921e-99	330.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2392Z@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1,SBP_bac_6
SRR25158390_k127_1632007_2	1283287.KB822575_gene134	2.672e-62	218.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4DP2T@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158390_k127_1632007_1	1120950.KB892746_gene3632	4.884e-96	321.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4DNQ9@85009|Propionibacteriales	201174|Actinobacteria	J	Methionine aminopeptidase	mapA	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158390_k127_1632007_0	1121335.Clst_0295	6.865e-146	482.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WHAB@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 3 family	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158390_k127_1633412_5	471853.Bcav_2954	2.098e-19	89.0	COG0510@1|root,COG0510@2|Bacteria,2I6BT@201174|Actinobacteria	201174|Actinobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_1633412_0	1122138.AQUZ01000073_gene4419	3.274e-268	833.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNCJ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158390_k127_1633412_4	1122609.AUGT01000024_gene420	5.864e-45	164.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4DR0X@85009|Propionibacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158390_k127_1633412_2	263358.VAB18032_25955	5.501e-94	327.0	COG0189@1|root,COG0189@2|Bacteria,2HI2Z@201174|Actinobacteria,4DBDA@85008|Micromonosporales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRR25158390_k127_1633412_1	1122138.AQUZ01000073_gene4416	3.028e-116	387.0	COG0742@1|root,COG0742@2|Bacteria,2I6DB@201174|Actinobacteria,4DWFG@85009|Propionibacteriales	201174|Actinobacteria	L	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_1633412_3	797299.HALLA_03760	2.917e-80	277.0	COG0697@1|root,arCOG00271@2157|Archaea,2XY2J@28890|Euryarchaeota,23Z1Z@183963|Halobacteria	183963|Halobacteria	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_164813_3	321955.AAGP01000009_gene326	1.235e-11	76.0	2C0QS@1|root,32R7D@2|Bacteria,2HYM2@201174|Actinobacteria,4F9FP@85019|Brevibacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_164813_0	1246448.ANAZ01000037_gene84	3.973e-226	721.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria,4EHW4@85012|Streptosporangiales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158390_k127_164813_1	1122611.KB903964_gene4919	1.06e-77	265.0	COG0664@1|root,COG0664@2|Bacteria,2I8QQ@201174|Actinobacteria,4EGBT@85012|Streptosporangiales	201174|Actinobacteria	T	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_164813_2	369723.Strop_1657	6.53e-28	124.0	2D0CU@1|root,32T8C@2|Bacteria,2GNI4@201174|Actinobacteria,4DF6V@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1660903_4	543632.JOJL01000006_gene9680	2.293e-09	63.0	COG3291@1|root,COG3408@1|root,COG3291@2|Bacteria,COG3408@2|Bacteria,2H8PD@201174|Actinobacteria,4D9SN@85008|Micromonosporales	201174|Actinobacteria	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158390_k127_1660903_3	743718.Isova_2548	1.156e-10	75.0	COG1082@1|root,COG1082@2|Bacteria,2IAKJ@201174|Actinobacteria,4F59I@85017|Promicromonosporaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158390_k127_1660903_1	1463825.JNXC01000006_gene2146	8.258e-160	526.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4EAHW@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_43
SRR25158390_k127_1660903_0	1172181.KB911700_gene7950	4.122e-255	807.0	COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria	201174|Actinobacteria	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
SRR25158390_k127_1660903_2	1121926.AXWO01000013_gene2180	1.558e-71	243.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_1679085_10	1120950.KB892748_gene3253	1.558e-06	55.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4DP69@85009|Propionibacteriales	201174|Actinobacteria	S	Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158390_k127_1679085_6	1120950.KB892748_gene3252	1.655e-135	445.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4DNZH@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158390_k127_1679085_8	397278.JOJN01000004_gene1215	1.387e-46	181.0	COG3206@1|root,COG3206@2|Bacteria,2GPMH@201174|Actinobacteria,4DR3I@85009|Propionibacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158390_k127_1679085_5	1033730.CAHG01000016_gene511	2.923e-139	450.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4DP2Q@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158390_k127_1679085_4	710696.Intca_3005	2.679e-139	453.0	COG1290@1|root,COG1290@2|Bacteria,2ICE4@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_N_2
SRR25158390_k127_1679085_9	710696.Intca_3006	2.544e-18	92.0	28ZFG@1|root,2ZM70@2|Bacteria,2HB49@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1679085_7	1120950.KB892748_gene3249	4.671e-62	219.0	2AIF4@1|root,318WM@2|Bacteria,2GK8R@201174|Actinobacteria,4DQE6@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
SRR25158390_k127_1679085_2	1169154.KB897781_gene5265	6.215e-165	528.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria	201174|Actinobacteria	J	3-5 exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158390_k127_1679085_3	479432.Sros_8137	1.386e-164	529.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158390_k127_1679085_1	477641.MODMU_3913	1.864e-213	668.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4ERTH@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_1679085_0	1120950.KB892748_gene3243	8.282e-311	973.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4DPMD@85009|Propionibacteriales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158390_k127_1682119_0	1120956.JHZK01000003_gene433	1.729e-286	888.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,1JQ85@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
SRR25158390_k127_1682119_1	314265.R2601_00775	9.58e-135	447.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2TVAB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158390_k127_1684628_10	357808.RoseRS_3083	6.813e-47	177.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_1684628_13	1265310.CCBD010000077_gene5300	1.137e-16	92.0	COG0346@1|root,COG0346@2|Bacteria,2IG1X@201174|Actinobacteria,2392H@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158390_k127_1684628_0	76114.ebA314	3.383e-201	646.0	COG5016@1|root,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VK1R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Conserved carboxylase domain	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
SRR25158390_k127_1684628_12	1232410.KI421413_gene900	3.599e-33	140.0	COG0511@1|root,COG0511@2|Bacteria,1N90D@1224|Proteobacteria,42XHJ@68525|delta/epsilon subdivisions,2WSU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158390_k127_1684628_11	1206725.BAFU01000048_gene1229	8.55e-40	158.0	COG0647@1|root,COG0647@2|Bacteria,2GPED@201174|Actinobacteria	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158390_k127_1684628_7	479434.Sthe_2818	7.903e-86	297.0	COG0574@1|root,COG0574@2|Bacteria,2G6K4@200795|Chloroflexi,27Z2C@189775|Thermomicrobia	189775|Thermomicrobia	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
SRR25158390_k127_1684628_2	479434.Sthe_2817	2.479e-196	632.0	COG3848@1|root,COG3848@2|Bacteria,2G8N4@200795|Chloroflexi,27YW7@189775|Thermomicrobia	189775|Thermomicrobia	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
SRR25158390_k127_1684628_1	1380393.JHVP01000004_gene514	2.76e-200	642.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EUXF@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_1684628_9	1463845.JOIG01000004_gene4634	5.797e-62	223.0	COG2084@1|root,COG2084@2|Bacteria,2ICA7@201174|Actinobacteria	201174|Actinobacteria	I	6-phosphogluconate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
SRR25158390_k127_1684628_8	1194165.CAJF01000011_gene1109	1.54e-71	249.0	COG1802@1|root,COG1802@2|Bacteria,2IBT4@201174|Actinobacteria,4FP81@85023|Microbacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_1684628_3	1077972.ARGLB_069_00150	2.114e-172	546.0	COG0346@1|root,COG0346@2|Bacteria,2GKY9@201174|Actinobacteria,1W8HU@1268|Micrococcaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	pheB	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158390_k127_1684628_4	1121019.AUMN01000011_gene3325	5.842e-144	470.0	COG2828@1|root,COG2828@2|Bacteria,2GJF3@201174|Actinobacteria,1WAMS@1268|Micrococcaceae	201174|Actinobacteria	S	PrpF protein	-	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
SRR25158390_k127_1684628_6	1068978.AMETH_2825	1.495e-91	314.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	ligK	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR25158390_k127_1684628_5	1121019.AUMN01000011_gene3327	1.495e-119	388.0	COG2120@1|root,COG2120@2|Bacteria,2GJP3@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	4.2.1.83	ko:K16515	ko00362,map00362	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	PIG-L
SRR25158390_k127_1703787_1	204669.Acid345_1679	2.942e-30	126.0	COG0531@1|root,COG0531@2|Bacteria,3Y6AZ@57723|Acidobacteria,2JME9@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158390_k127_1703787_0	204669.Acid345_1678	3.643e-136	443.0	COG4932@1|root,COG4932@2|Bacteria,3Y98G@57723|Acidobacteria,2JP50@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158390_k127_1717995_0	1386089.N865_12270	6.324e-123	406.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria,4FFE4@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_1717995_1	1449976.KALB_7269	8.689e-73	248.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria,4DYXA@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158390_k127_1728665_6	653045.Strvi_2028	1.005e-28	123.0	2EA6A@1|root,334B4@2|Bacteria,2II4E@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4439
SRR25158390_k127_1728665_0	1120950.KB892747_gene3709	1.908e-281	876.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4DN8W@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158390_k127_1728665_5	935839.JAGJ01000026_gene3631	6.278e-51	187.0	COG0640@1|root,COG0640@2|Bacteria,2HGTP@201174|Actinobacteria,4F5N1@85017|Promicromonosporaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_1728665_1	471853.Bcav_1213	5.643e-104	353.0	COG0477@1|root,COG0477@2|Bacteria,2I2JQ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1728665_3	1137271.AZUM01000008_gene2102	5.649e-95	325.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4E0A0@85010|Pseudonocardiales	201174|Actinobacteria	M	Capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_1728665_2	479435.Kfla_5999	2.39e-101	348.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQRB@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_1728665_4	44060.JODL01000009_gene1913	5.006e-55	195.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158390_k127_1731517_1	103733.JNYO01000009_gene4635	2.482e-60	216.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158390_k127_1731517_0	1033730.CAHG01000007_gene2620	1.182e-157	503.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DNYV@85009|Propionibacteriales	201174|Actinobacteria	F	Adenosine/AMP deaminase	add1	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158390_k127_1731517_2	247156.NFA_54390	1.104e-30	126.0	2E3QV@1|root,32YNP@2|Bacteria,2GQQZ@201174|Actinobacteria,4G392@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158390_k127_1731517_3	1068978.AMETH_1273	1.37e-26	112.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
SRR25158390_k127_1735960_8	1122138.AQUZ01000004_gene935	7.797e-83	281.0	299E4@1|root,2ZWGX@2|Bacteria,2GM90@201174|Actinobacteria,4DQ7U@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3145
SRR25158390_k127_1735960_0	1068980.ARVW01000001_gene7375	1.276e-278	871.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria,4E24H@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158390_k127_1735960_9	1137271.AZUM01000004_gene4083	3.825e-62	217.0	COG0346@1|root,COG0346@2|Bacteria,2IHR7@201174|Actinobacteria,4E4UI@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_1735960_11	710696.Intca_1802	1.448e-56	201.0	COG1846@1|root,COG1846@2|Bacteria,2I683@201174|Actinobacteria,4FJCT@85021|Intrasporangiaceae	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158390_k127_1735960_5	414996.IL38_02515	1.126e-94	319.0	COG2035@1|root,COG2035@2|Bacteria,2I8HU@201174|Actinobacteria,407XR@622450|Actinopolysporales	201174|Actinobacteria	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
SRR25158390_k127_1735960_10	1125971.ASJB01000043_gene3396	4.757e-60	211.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4E45T@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_1735960_4	1121272.KB903290_gene4575	1.413e-101	338.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DCNR@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_1735960_7	1121272.KB903290_gene4574	2.437e-84	295.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4D9VC@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158390_k127_1735960_2	471853.Bcav_4078	4.895e-124	406.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_1735960_6	471853.Bcav_4079	4.977e-94	327.0	COG1277@1|root,COG1277@2|Bacteria,2IG8D@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158390_k127_1735960_3	219305.MCAG_01618	2.133e-107	364.0	COG0477@1|root,COG2814@2|Bacteria,2HCHA@201174|Actinobacteria,4D8ZA@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1735960_1	2074.JNYD01000022_gene1437	7.343e-212	692.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXJW@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158390_k127_1763300_6	1089545.KB913037_gene9540	1.535e-28	133.0	COG0419@1|root,COG3055@1|root,COG0419@2|Bacteria,COG3055@2|Bacteria,2I9QM@201174|Actinobacteria	201174|Actinobacteria	L	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
SRR25158390_k127_1763300_2	298654.FraEuI1c_4644	1.232e-117	407.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Peptidase_S8,SLH,fn3
SRR25158390_k127_1763300_8	1304275.C41B8_08470	7.986e-13	81.0	2C6T2@1|root,32ZMJ@2|Bacteria,1R3H1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3892
SRR25158390_k127_1763300_4	391625.PPSIR1_27108	9.345e-59	225.0	28H5N@1|root,2Z7I8@2|Bacteria,1RC6E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1763300_0	1120950.KB892749_gene3340	0.0	1026.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4DQ0K@85009|Propionibacteriales	201174|Actinobacteria	T	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158390_k127_1763300_5	471852.Tcur_3729	1.356e-38	151.0	2DA1Q@1|root,32TUF@2|Bacteria,2GKR3@201174|Actinobacteria,4EK7A@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1763300_3	1120950.KB892749_gene3341	1.886e-96	327.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4DQEN@85009|Propionibacteriales	201174|Actinobacteria	T	Domain present in PSD-95, Dlg, and ZO-1/2.	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158390_k127_1763300_1	1120950.KB892749_gene3343	3.769e-126	415.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158390_k127_1763300_7	68260.JOAY01000002_gene5088	8.488e-23	103.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria	201174|Actinobacteria	H	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158390_k127_1771201_0	1120950.KB892823_gene520	1.525e-112	388.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DN8K@85009|Propionibacteriales	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158390_k127_1771201_1	1122611.KB903974_gene2938	0.0002039	47.0	2E9EF@1|root,333MW@2|Bacteria,2I141@201174|Actinobacteria,4EKRV@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_177444_7	1386089.N865_15090	2.382e-61	220.0	COG1765@1|root,COG1765@2|Bacteria,2IG8A@201174|Actinobacteria,4FJTH@85021|Intrasporangiaceae	201174|Actinobacteria	O	redox protein regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_177444_9	298655.KI912266_gene3382	1.8e-59	220.0	COG1296@1|root,COG1296@2|Bacteria,2IKHA@201174|Actinobacteria	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158390_k127_177444_3	1209984.BN978_06070	5.534e-148	479.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158390_k127_177444_0	743718.Isova_0730	0.0	1280.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4F41G@85017|Promicromonosporaceae	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158390_k127_177444_8	2002.JOEQ01000013_gene5470	6.478e-61	220.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJD9@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_177444_5	1246995.AFR_33750	6.94e-98	322.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria,4DES5@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_177444_6	1121272.KB903283_gene5039	4.218e-80	271.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria,4DDTB@85008|Micromonosporales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158390_k127_177444_1	28444.JODQ01000007_gene5159	6.505e-271	855.0	COG2866@1|root,COG2866@2|Bacteria,2IAU2@201174|Actinobacteria,4EFJH@85012|Streptosporangiales	201174|Actinobacteria	E	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Peptidase_M14
SRR25158390_k127_177444_2	1464048.JNZS01000007_gene4483	6.817e-170	541.0	COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4DA82@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR25158390_k127_177444_4	1146883.BLASA_2982	3.876e-104	350.0	COG2807@1|root,COG2807@2|Bacteria,2GP5W@201174|Actinobacteria,4EVM7@85013|Frankiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRR25158390_k127_1782837_0	1123320.KB889749_gene4536	6.155e-157	511.0	COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_1782837_1	1463926.JOCA01000036_gene1374	5.382e-30	138.0	COG0823@1|root,COG0823@2|Bacteria,2I308@201174|Actinobacteria	201174|Actinobacteria	U	Lipoprotein LpqB beta-propeller domain	lpqB	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
SRR25158390_k127_1798051_6	397278.JOJN01000001_gene2848	1.924e-58	217.0	COG1403@1|root,COG1403@2|Bacteria,2I9AH@201174|Actinobacteria,4DMZA@85009|Propionibacteriales	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_1798051_14	525260.HMPREF0276_1119	1.436e-06	53.0	28W2S@1|root,2ZI3Q@2|Bacteria,2HC77@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1798051_12	1370125.AUWT01000029_gene735	9.663e-16	79.0	COG1487@1|root,COG1487@2|Bacteria,2ID5E@201174|Actinobacteria,23AGT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
SRR25158390_k127_1798051_17	1121019.AUMN01000007_gene2540	3.243e-05	50.0	COG1487@1|root,COG1487@2|Bacteria,2ID5E@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
SRR25158390_k127_1798051_4	258052.JNYV01000002_gene2063	3.81e-102	338.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,2M0RX@2063|Kitasatospora	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_1798051_7	105420.BBPO01000031_gene6590	3.355e-47	175.0	COG0789@1|root,COG0789@2|Bacteria,2IC98@201174|Actinobacteria,2NGH2@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_1798051_9	465515.Mlut_22980	1.876e-44	166.0	COG1846@1|root,COG3177@1|root,COG1846@2|Bacteria,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,1W8NF@1268|Micrococcaceae	201174|Actinobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158390_k127_1798051_13	586413.CCDL010000001_gene768	4.624e-12	78.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,23JBT@182709|Oceanobacillus	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1798051_3	1114959.SZMC14600_01594	2.222e-106	355.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4E2HG@85010|Pseudonocardiales	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_2906 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1798051_0	500153.JOEK01000006_gene5423	0.0	1102.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158390_k127_1798051_10	1464048.JNZS01000001_gene156	1.641e-34	136.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,4DF4A@85008|Micromonosporales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158390_k127_1798051_8	1120950.KB892768_gene5294	5.605e-45	167.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria,4DV1W@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SRR25158390_k127_1798051_11	1160137.KB907307_gene983	4.198e-29	124.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,4G3AM@85025|Nocardiaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158390_k127_1798051_2	1121946.AUAX01000022_gene3785	7.832e-221	719.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DBE3@85008|Micromonosporales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR25158390_k127_1798051_15	479431.Namu_0251	1.454e-06	55.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4ET7Y@85013|Frankiales	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	yedX	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158390_k127_1798051_1	1120950.KB892707_gene4731	5.883e-251	778.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4DNNP@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_1798051_5	1449347.JQLN01000002_gene2392	4.418e-66	230.0	COG0454@1|root,COG0456@2|Bacteria,2IFPI@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158390_k127_1803906_7	675635.Psed_1297	2.165e-69	242.0	COG1011@1|root,COG1011@2|Bacteria,2IIMR@201174|Actinobacteria,4EEY6@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158390_k127_1803906_9	1121272.KB903291_gene3589	3.272e-47	172.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4DF3Z@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158390_k127_1803906_0	1121946.AUAX01000025_gene6388	3.67e-180	582.0	COG2072@1|root,COG2072@2|Bacteria,2GKBD@201174|Actinobacteria,4D95M@85008|Micromonosporales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158390_k127_1803906_6	882083.SacmaDRAFT_3403	2.671e-89	297.0	COG1396@1|root,COG1396@2|Bacteria,2GXAS@201174|Actinobacteria,4E2KY@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158390_k127_1803906_5	1137271.AZUM01000001_gene585	2.123e-93	311.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4E35S@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158390_k127_1803906_12	1137271.AZUM01000001_gene586	2.202e-28	126.0	2DMQN@1|root,32T1U@2|Bacteria,2GS5T@201174|Actinobacteria,4E6JM@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158390_k127_1803906_10	1120950.KB892820_gene721	1.068e-46	171.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4DS57@85009|Propionibacteriales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
SRR25158390_k127_1803906_11	110319.CF8_3965	2.461e-30	122.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158390_k127_1803906_3	324602.Caur_1080	2.751e-121	408.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi,376PJ@32061|Chloroflexia	32061|Chloroflexia	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SRR25158390_k127_1803906_1	1122622.ATWJ01000013_gene50	4.178e-124	406.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4FH83@85021|Intrasporangiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_1803906_4	110319.CF8_1584	2.675e-118	393.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	MA20_42580	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_1803906_2	110319.CF8_0940	7.696e-122	400.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DNIE@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1803906_8	710696.Intca_0362	3.984e-51	184.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4FIV4@85021|Intrasporangiaceae	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	braD	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1806959_1	935866.JAER01000032_gene2393	1.016e-176	555.0	COG3185@1|root,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,4DNX1@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	hpd	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158390_k127_1806959_6	561175.KB894101_gene4653	3.425e-71	253.0	COG3473@1|root,COG3473@2|Bacteria,2GKP7@201174|Actinobacteria,4EMAU@85012|Streptosporangiales	201174|Actinobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158390_k127_1806959_0	1479235.KK366039_gene677	7.04e-240	752.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XHUS@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
SRR25158390_k127_1806959_9	58344.JOEL01000046_gene798	9.738e-57	207.0	COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria	201174|Actinobacteria	Q	Catalyzes the conversion of maleate to fumarate	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158390_k127_1806959_3	1156844.KB891831_gene4729	1.608e-167	537.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT2	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_1806959_4	928724.SacglDRAFT_02514	2.322e-117	394.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4DXER@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	dghA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_1806959_7	1463857.JOFZ01000015_gene955	4.959e-69	237.0	COG2164@1|root,COG2164@2|Bacteria,2I8JP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
SRR25158390_k127_1806959_2	405948.SACE_3773	9.339e-169	546.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4E1PC@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_1806959_5	330084.JNYZ01000027_gene8351	2.396e-96	327.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DZ4C@85010|Pseudonocardiales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_1806959_8	928724.SacglDRAFT_03388	4.672e-60	214.0	COG1802@1|root,COG1802@2|Bacteria,2GMZ9@201174|Actinobacteria,4DZZZ@85010|Pseudonocardiales	201174|Actinobacteria	K	GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_1816552_0	882083.SacmaDRAFT_4800	1.89e-295	912.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DXAH@85010|Pseudonocardiales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL1	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158390_k127_1816552_19	1521187.JPIM01000033_gene2020	1.151e-26	123.0	COG0823@1|root,COG0823@2|Bacteria,2G8T8@200795|Chloroflexi,377EP@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158390_k127_1816552_15	1120950.KB892775_gene1170	1.688e-42	160.0	2F62G@1|root,33YKU@2|Bacteria,2IHNY@201174|Actinobacteria,4DRHE@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1816552_8	1120950.KB892775_gene1171	2.083e-82	281.0	COG3142@1|root,COG3142@2|Bacteria,2GKI8@201174|Actinobacteria,4DQWU@85009|Propionibacteriales	201174|Actinobacteria	P	CutC family	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
SRR25158390_k127_1816552_17	981369.JQMJ01000004_gene6360	4.145e-33	130.0	COG4339@1|root,COG4339@2|Bacteria,2IQ60@201174|Actinobacteria,2NJHU@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031
SRR25158390_k127_1816552_11	469371.Tbis_1382	2.035e-62	222.0	COG4339@1|root,COG4339@2|Bacteria,2GMYQ@201174|Actinobacteria,4E451@85010|Pseudonocardiales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031,HD
SRR25158390_k127_1816552_3	367299.JOEE01000001_gene1669	1.076e-129	427.0	COG0477@1|root,COG2814@2|Bacteria,2GMHP@201174|Actinobacteria,4FF4P@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1816552_1	1120950.KB892775_gene1176	1.301e-240	764.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DPFY@85009|Propionibacteriales	201174|Actinobacteria	L	AAA domain	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158390_k127_1816552_14	1278078.G419_16108	5.197e-50	182.0	COG2044@1|root,COG2044@2|Bacteria,2HI3Q@201174|Actinobacteria,4G2MA@85025|Nocardiaceae	201174|Actinobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158390_k127_1816552_6	33876.JNXY01000010_gene2543	1.096e-89	301.0	COG3217@1|root,COG3217@2|Bacteria,2GND9@201174|Actinobacteria,4DD6C@85008|Micromonosporales	201174|Actinobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158390_k127_1816552_10	189753.AXAS01000013_gene5751	2.539e-78	270.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,3JVXR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1816552_7	713586.KB900536_gene2259	2.993e-89	301.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_1816552_12	1122138.AQUZ01000019_gene8182	2.233e-55	203.0	COG1595@1|root,COG1595@2|Bacteria,2H45C@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1816552_21	1214101.BN159_4300	6.537e-12	75.0	2DGEZ@1|root,2ZVQ5@2|Bacteria,2GYKS@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_1816552_9	1214101.BN159_4299	1.003e-81	279.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158390_k127_1816552_13	500153.JOEK01000005_gene2196	1.19e-52	191.0	COG1522@1|root,COG1522@2|Bacteria,2GN6I@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158390_k127_1816552_5	1122182.KB903813_gene2590	3.861e-107	357.0	COG1834@1|root,COG1834@2|Bacteria,2GNTN@201174|Actinobacteria,4D98D@85008|Micromonosporales	201174|Actinobacteria	E	amidinotransferase	-	GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158390_k127_1816552_20	1120950.KB892787_gene126	8.472e-24	108.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria,4DSEC@85009|Propionibacteriales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_1816552_18	1179773.BN6_13240	3.68e-30	123.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria,4ED1W@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_1816552_2	105425.BBPL01000003_gene6919	1.015e-156	501.0	COG0462@1|root,COG0462@2|Bacteria,2GKR2@201174|Actinobacteria,2NKRC@228398|Streptacidiphilus	201174|Actinobacteria	EF	Phosphoribosyl synthetase-associated domain	prs_1	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158390_k127_1816552_4	263358.VAB18032_06920	8.667e-117	391.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DC2Y@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1816552_16	526225.Gobs_3725	3.178e-37	153.0	COG1522@1|root,COG1522@2|Bacteria,2IMT5@201174|Actinobacteria	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158390_k127_1829942_2	471857.Svir_11760	6.102e-187	587.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4DXYM@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158390_k127_1829942_9	1122609.AUGT01000005_gene1689	1.979e-41	166.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria,4DRTF@85009|Propionibacteriales	201174|Actinobacteria	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158390_k127_1829942_10	479433.Caci_7357	3.83e-36	151.0	2DQ1M@1|root,32UNB@2|Bacteria,2GJD1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1829942_5	222534.KB893746_gene2699	1.893e-72	251.0	COG2378@1|root,COG2378@2|Bacteria,2H5IT@201174|Actinobacteria,4EVY7@85013|Frankiales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_1829942_6	1121382.JQKG01000003_gene4213	4.053e-67	245.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_1829942_1	414996.IL38_12535	3.452e-233	732.0	COG0366@1|root,COG0366@2|Bacteria,2H1PP@201174|Actinobacteria,40809@622450|Actinopolysporales	2|Bacteria	G	Alpha amylase, catalytic domain	aglA	-	3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
SRR25158390_k127_1829942_8	1713.JOFV01000005_gene2400	2.247e-58	205.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4F1D1@85016|Cellulomonadaceae	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158390_k127_1829942_7	196162.Noca_1377	3.988e-60	216.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4DRBU@85009|Propionibacteriales	201174|Actinobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158390_k127_1829942_4	1068980.ARVW01000001_gene4013	1.725e-84	286.0	COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria,4E08E@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_1829942_3	110319.CF8_1067	7.846e-97	327.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DNMY@85009|Propionibacteriales	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158390_k127_1829942_0	471852.Tcur_1339	1.407e-305	950.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4EG49@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158390_k127_1829942_12	1120959.ATXF01000005_gene896	1.385e-23	103.0	2E3I3@1|root,32YGJ@2|Bacteria,2GV2N@201174|Actinobacteria,4FQCU@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
SRR25158390_k127_1829942_11	1122138.AQUZ01000075_gene7356	7.82e-36	146.0	COG2852@1|root,COG2852@2|Bacteria,2IGEW@201174|Actinobacteria,4DUUG@85009|Propionibacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158390_k127_1831328_0	1463845.JOIG01000011_gene393	1.779e-130	422.0	COG1879@1|root,COG1879@2|Bacteria,2I43Z@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	rhaS	-	-	ko:K02058,ko:K10559	ko02010,map02010	M00220,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.9	-	-	Peripla_BP_4
SRR25158390_k127_1831328_1	68170.KL590524_gene3456	5.632e-104	341.0	COG4952@1|root,COG4952@2|Bacteria,2GK1Z@201174|Actinobacteria,4DZ7P@85010|Pseudonocardiales	201174|Actinobacteria	M	Isomerase	rhaI	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,RhaA
SRR25158390_k127_1864359_1	1134445.AJJM01000016_gene312	1.703e-33	131.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt ABC transporter	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158390_k127_1864359_0	1394178.AWOO02000040_gene8587	4.984e-121	398.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4EFVM@85012|Streptosporangiales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158390_k127_1864359_2	33876.JNXY01000019_gene7656	2.13e-12	69.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4DE0Q@85008|Micromonosporales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158390_k127_1865822_0	570268.ANBB01000002_gene372	3.286e-69	254.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4EGNK@85012|Streptosporangiales	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158390_k127_1867438_4	1237500.ANBA01000009_gene1392	1.085e-26	114.0	COG2329@1|root,COG2329@2|Bacteria,2GQZB@201174|Actinobacteria,4EKAM@85012|Streptosporangiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158390_k127_1867438_1	2074.JNYD01000007_gene2100	9.515e-99	339.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DY5S@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YibE F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158390_k127_1867438_0	1120950.KB892739_gene3960	5.378e-250	776.0	COG0441@1|root,COG0441@2|Bacteria,2I4F4@201174|Actinobacteria,4DX2C@85009|Propionibacteriales	201174|Actinobacteria	J	Anticodon binding domain	glyQS	GO:0000959,GO:0003674,GO:0003824,GO:0004081,GO:0004551,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009987,GO:0010467,GO:0015959,GO:0015960,GO:0015965,GO:0015966,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016875,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019752,GO:0031982,GO:0032543,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0055086,GO:0070062,GO:0070127,GO:0070150,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0140053,GO:0140098,GO:0140101,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903561,GO:1990742	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158390_k127_1867438_2	345341.KUTG_07881	1.774e-64	238.0	COG1595@1|root,COG1595@2|Bacteria,2I12G@201174|Actinobacteria,4ECCQ@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1867438_3	408672.NBCG_05435	2.044e-57	207.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DNZA@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158390_k127_1872235_5	446470.Snas_2285	9.725e-22	99.0	2EGRJ@1|root,33AHR@2|Bacteria,2GY62@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158390_k127_1872235_3	469383.Cwoe_3355	3.21e-70	248.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_1872235_2	1120950.KB892785_gene247	1.695e-81	279.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,RmlD_sub_bind
SRR25158390_k127_1872235_0	593907.Celgi_0885	1.497e-252	786.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4F0EC@85016|Cellulomonadaceae	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_1872235_4	1121017.AUFG01000001_gene3027	7.614e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria,4FH8G@85021|Intrasporangiaceae	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1872235_1	408672.NBCG_04544	1.077e-136	438.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DN1G@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158390_k127_1877951_28	1352941.M877_13315	2.622e-09	68.0	COG2234@1|root,COG2234@2|Bacteria,2I9BM@201174|Actinobacteria	201174|Actinobacteria	G	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158390_k127_1877951_7	710685.MycrhN_4224	1.499e-127	424.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,233GJ@1762|Mycobacteriaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,rve,rve_3
SRR25158390_k127_1877951_12	1120950.KB892745_gene2925	2.188e-81	286.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4DR6P@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_1877951_3	1122609.AUGT01000002_gene4048	8.744e-170	543.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DNMA@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158390_k127_1877951_16	1032480.MLP_23270	4.604e-75	259.0	COG2318@1|root,COG2318@2|Bacteria,2II7R@201174|Actinobacteria,4DR0T@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_1877951_27	443218.AS9A_2432	6.456e-24	102.0	COG3576@1|root,COG3576@2|Bacteria,2I2W4@201174|Actinobacteria,2399K@1762|Mycobacteriaceae	201174|Actinobacteria	S	pyridoxamine 5'-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_1877951_26	66869.JNXG01000002_gene6582	2.059e-34	149.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria,41AAA@629295|Streptomyces griseus group	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_1877951_6	644283.Micau_3702	1.124e-133	435.0	COG0726@1|root,COG0726@2|Bacteria,2GMI0@201174|Actinobacteria,4D8EA@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolases family 11	xlnB	GO:0005575,GO:0016020	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Glyco_hydro_11
SRR25158390_k127_1877951_0	426716.JOAJ01000001_gene1192	2.864e-201	632.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FWEK@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE3_2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_1877951_1	326424.FRAAL3411	2.434e-189	602.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_1877951_5	2074.JNYD01000058_gene3330	6.407e-149	483.0	COG0596@1|root,COG0596@2|Bacteria,2GMHK@201174|Actinobacteria,4E53S@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_1877951_20	114615.BRADO2267	4.19e-48	184.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,3JS0B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_1877951_19	570967.JMLV01000004_gene524	2.076e-49	196.0	COG0683@1|root,COG0683@2|Bacteria,1Q8UT@1224|Proteobacteria,2TVG4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	MA20_14135	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_1877951_18	1121116.KB894775_gene1096	6.895e-53	195.0	COG0410@1|root,COG3945@1|root,COG0410@2|Bacteria,COG3945@2|Bacteria,1MVVC@1224|Proteobacteria,2VK1I@28216|Betaproteobacteria,4AIYQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,Hemerythrin
SRR25158390_k127_1877951_24	883080.HMPREF9697_01166	2.833e-37	151.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2TT3V@28211|Alphaproteobacteria,3JUY0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1877951_23	479434.Sthe_2886	5.559e-44	182.0	COG4177@1|root,COG4177@2|Bacteria,2G8KF@200795|Chloroflexi,27YZG@189775|Thermomicrobia	189775|Thermomicrobia	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_1877951_13	1298880.AUEV01000007_gene4711	1.885e-78	271.0	COG0491@1|root,COG0491@2|Bacteria,2IAXY@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_1877951_9	426355.Mrad2831_3250	7.421e-102	339.0	COG2084@1|root,COG2084@2|Bacteria,1MWR4@1224|Proteobacteria,2U157@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158390_k127_1877951_21	94624.Bpet1660	7.431e-46	169.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2VV0R@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_1877951_11	1394178.AWOO02000001_gene1230	1.317e-81	281.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4EHG8@85012|Streptosporangiales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158390_k127_1877951_25	1283287.KB822577_gene3070	5.248e-35	136.0	COG1359@1|root,COG1359@2|Bacteria,2IRF2@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158390_k127_1877951_8	1121924.ATWH01000004_gene2248	1.807e-119	402.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria	201174|Actinobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158390_k127_1877951_14	1077972.ARGLB_094_00470	4.124e-78	274.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,1W93S@1268|Micrococcaceae	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
SRR25158390_k127_1877951_17	1001240.GY21_05140	1.758e-63	228.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4FPDY@85023|Microbacteriaceae	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.25,4.1.3.34	ko:K01644,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158390_k127_1877951_2	1077972.ARGLB_094_00450	1.982e-171	559.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_1877951_15	1077972.ARGLB_094_00550	4.804e-78	267.0	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_1877951_22	62977.ACIAD2538	1.409e-44	169.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,1S6JH@1236|Gammaproteobacteria,3NT9J@468|Moraxellaceae	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	HA62_21275	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158390_k127_1877951_4	1121926.AXWO01000019_gene1912	8.674e-153	487.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_1877951_10	1312959.KI914662_gene3895	5.892e-91	308.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,1WAEU@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158390_k127_1877951_29	219305.MCAG_04077	0.000601	43.0	28KEA@1|root,2ZA0J@2|Bacteria,2I9YN@201174|Actinobacteria,4DCRZ@85008|Micromonosporales	201174|Actinobacteria	H	Sulfotransferase domain	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
SRR25158390_k127_1878715_0	1122622.ATWJ01000007_gene1450	0.0	1422.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4FEA5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR25158390_k127_1878715_5	1713.JOFV01000008_gene3252	7.183e-131	435.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4F133@85016|Cellulomonadaceae	201174|Actinobacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_1878715_2	263358.VAB18032_08585	1.286e-186	595.0	COG2182@1|root,COG2182@2|Bacteria,2I2J8@201174|Actinobacteria,4DBRF@85008|Micromonosporales	201174|Actinobacteria	G	extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_1878715_3	391037.Sare_0748	4.352e-157	501.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4DCIU@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	malF	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158390_k127_1878715_6	1869.MB27_25020	5.881e-128	415.0	COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,4DCM5@85008|Micromonosporales	201174|Actinobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158390_k127_1878715_9	1237500.ANBA01000013_gene4013	4.547e-64	222.0	COG4954@1|root,COG4954@2|Bacteria,2IFBK@201174|Actinobacteria,4EPAA@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2000
SRR25158390_k127_1878715_8	33876.JNXY01000018_gene7852	1.733e-99	333.0	COG2207@1|root,COG2207@2|Bacteria,2GNEB@201174|Actinobacteria,4DCIT@85008|Micromonosporales	201174|Actinobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158390_k127_1878715_4	1150864.MILUP08_46513	1.902e-145	473.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4DASY@85008|Micromonosporales	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_1878715_1	356851.JOAN01000015_gene2696	3.839e-202	638.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DAN2@85008|Micromonosporales	201174|Actinobacteria	G	Beta-glucosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158390_k127_1878715_7	1121926.AXWO01000008_gene2856	1.274e-120	398.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
SRR25158390_k127_1878715_10	452652.KSE_57740	9.967e-63	221.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria,2M4TP@2063|Kitasatospora	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
SRR25158390_k127_188377_1	40571.JOEA01000005_gene4340	1.148e-36	141.0	COG2271@1|root,COG2271@2|Bacteria,2GVNB@201174|Actinobacteria,4ECHI@85010|Pseudonocardiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_188377_2	479435.Kfla_4600	3.115e-13	82.0	arCOG13021@1|root,33BFU@2|Bacteria,2GTY3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_188377_0	1122138.AQUZ01000008_gene3778	7.469e-120	391.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4DNDY@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158390_k127_1892526_0	882083.SacmaDRAFT_3031	1.59e-31	132.0	COG3409@1|root,COG3409@2|Bacteria,2HUBB@201174|Actinobacteria,4E7IY@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1892526_2	1169143.KB911035_gene2338	1.596e-10	70.0	COG2197@1|root,COG2197@2|Bacteria,1NXKF@1224|Proteobacteria,2W0UU@28216|Betaproteobacteria,1K4Z4@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_8,PAS_9
SRR25158390_k127_1892844_5	1128421.JAGA01000002_gene1529	7.075e-76	258.0	COG0259@1|root,COG0259@2|Bacteria,2NQT9@2323|unclassified Bacteria	2|Bacteria	H	Pfam:PNPOx_C	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
SRR25158390_k127_1892844_4	1169161.KB897731_gene269	2.799e-89	304.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158390_k127_1892844_1	1120950.KB892779_gene972	4.494e-190	602.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4DPE1@85009|Propionibacteriales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR25158390_k127_1892844_6	1449353.JQMQ01000005_gene3447	3.156e-52	186.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,2NJ30@228398|Streptacidiphilus	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158390_k127_1892844_3	1298863.AUEP01000004_gene2306	1.516e-94	312.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4DNIV@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158390_k127_1892844_2	1003195.SCAT_3486	7.688e-100	332.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158390_k127_1892844_0	1134445.AJJM01000032_gene1376	5.799e-220	696.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158390_k127_1894822_3	585531.HMPREF0063_12418	4.467e-27	113.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4DNA0@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158390_k127_1894822_1	446466.Cfla_1530	3.733e-263	826.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4F0MZ@85016|Cellulomonadaceae	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158390_k127_1894822_0	397278.JOJN01000001_gene2614	0.0	1013.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4DN14@85009|Propionibacteriales	201174|Actinobacteria	D	Ftsk_gamma	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158390_k127_1894822_2	65497.JODV01000014_gene3370	8.758e-189	603.0	COG1292@1|root,COG1292@2|Bacteria,2GJX0@201174|Actinobacteria,4DXDK@85010|Pseudonocardiales	201174|Actinobacteria	U	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
SRR25158390_k127_1894822_4	1122609.AUGT01000002_gene3864	4.162e-22	96.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4DNHY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158390_k127_1900113_4	1283299.AUKG01000001_gene3463	6.645e-45	185.0	COG1216@1|root,COG1216@2|Bacteria,2HFMY@201174|Actinobacteria,4CSCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1900113_3	671143.DAMO_0611	2.08e-45	182.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158390_k127_1900113_1	1254432.SCE1572_32675	6.455e-71	250.0	COG2227@1|root,COG2227@2|Bacteria,1R0CY@1224|Proteobacteria	1224|Proteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_1900113_2	194867.ALBQ01000017_gene2388	1.993e-63	226.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,2TREE@28211|Alphaproteobacteria,2JZZE@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158390_k127_1900113_0	671143.DAMO_0610	2.054e-71	252.0	COG0494@1|root,COG0494@2|Bacteria,2NPTC@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_1900113_5	671143.DAMO_0483	2.324e-35	139.0	COG3222@1|root,COG3222@2|Bacteria,2NRHT@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SRR25158390_k127_1900449_0	1123320.KB889596_gene8708	6.161e-173	550.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158390_k127_1900449_2	561175.KB894098_gene5466	8.615e-75	267.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4EIPZ@85012|Streptosporangiales	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158390_k127_1900449_1	1122609.AUGT01000002_gene4021	1.419e-90	304.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4DNKD@85009|Propionibacteriales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158390_k127_192216_1	1123255.JHYS01000007_gene1677	1.244e-139	465.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria,4AAAP@80864|Comamonadaceae	28216|Betaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158390_k127_192216_3	479435.Kfla_6849	6.957e-46	170.0	COG2050@1|root,COG2050@2|Bacteria,2IKWI@201174|Actinobacteria,4DRS2@85009|Propionibacteriales	201174|Actinobacteria	Q	Thioesterase superfamily	paaD	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRR25158390_k127_192216_0	571166.KI421509_gene2869	5.751e-171	544.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.174	ko:K07823	ko00362,ko01120,map00362,map01120	-	R00829	RC00004,RC00326	ko00000,ko00001,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_192216_2	935866.JAER01000050_gene879	7.853e-82	285.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DN9S@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158390_k127_192216_4	367299.JOEE01000002_gene2389	3.567e-17	81.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4FFEF@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158390_k127_19538_0	1449976.KALB_3441	1.672e-171	550.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4E059@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phytoene dehydrogenase-like oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158390_k127_19538_1	105422.BBPM01000012_gene7065	2.571e-29	119.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,2NJGP@228398|Streptacidiphilus	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	scoF4	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158390_k127_1958205_1	543632.JOJL01000042_gene4508	3.346e-41	154.0	COG0372@1|root,COG0372@2|Bacteria,2H9YP@201174|Actinobacteria	201174|Actinobacteria	C	Citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_1958205_2	443598.AUFA01000037_gene5093	1.462e-40	161.0	COG1082@1|root,COG1082@2|Bacteria,1N0QZ@1224|Proteobacteria,2UDUZ@28211|Alphaproteobacteria,3K1J2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158390_k127_1958205_0	1123023.JIAI01000034_gene4126	2.115e-92	321.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4E0V1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158390_k127_1963302_10	1179773.BN6_58270	5.035e-53	195.0	COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria,4E90C@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_1963302_6	1179773.BN6_58280	1.91e-104	344.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_1963302_14	1089545.KB913037_gene7384	6.507e-22	98.0	COG4423@1|root,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
SRR25158390_k127_1963302_12	1089544.KB912942_gene3115	9.087e-34	134.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158390_k127_1963302_8	2002.JOEQ01000015_gene5059	1.099e-56	200.0	COG0596@1|root,COG0596@2|Bacteria,2IJXZ@201174|Actinobacteria,4EKFA@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_1963302_0	1445613.JALM01000015_gene5651	4.615e-276	857.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4E1U7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6,2.5.1.66	ko:K01652,ko:K12673	ko00290,ko00331,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00331,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570,M00674	R00006,R00014,R00226,R03050,R04672,R04673,R05465,R08648	RC00027,RC00106,RC00215,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_1963302_4	1120950.KB892792_gene2393	7.402e-140	448.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,4DU98@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158390_k127_1963302_3	1894.JOER01000049_gene5039	2.072e-150	487.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158390_k127_1963302_1	1352941.M877_33570	1.632e-200	632.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158390_k127_1963302_15	67257.JODR01000015_gene5903	2.768e-18	91.0	2EGVE@1|root,33AMN@2|Bacteria,2GQWM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1963302_13	1123320.KB889662_gene1604	4.18e-26	115.0	2ECBY@1|root,336AB@2|Bacteria,2GXKR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1963302_5	1120950.KB892708_gene4395	9.417e-124	404.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DPF5@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_1963302_2	211114.JOEF01000035_gene1459	2.717e-165	526.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1963302_7	196162.Noca_2623	9.764e-82	282.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4DN4Z@85009|Propionibacteriales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158390_k127_1963302_9	28042.GU90_12790	1.534e-55	214.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4DXVM@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Phosphoglycerate mutase	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158390_k127_1963302_11	1172179.AUKV01000011_gene3868	1.819e-42	159.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158390_k127_196352_9	471852.Tcur_2118	2.27e-24	104.0	COG1196@1|root,COG1196@2|Bacteria,2GJBD@201174|Actinobacteria,4EFI7@85012|Streptosporangiales	201174|Actinobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
SRR25158390_k127_196352_0	105420.BBPO01000003_gene1303	0.0	1149.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,2NI0C@228398|Streptacidiphilus	201174|Actinobacteria	KT	Region found in RelA / SpoT proteins	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158390_k127_196352_7	397278.JOJN01000004_gene1303	1.446e-60	214.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4DQKV@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158390_k127_196352_10	469371.Tbis_2062	1.305e-20	96.0	COG1862@1|root,COG1862@2|Bacteria,2IQSP@201174|Actinobacteria	201174|Actinobacteria	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158390_k127_196352_1	196162.Noca_2387	3.26e-162	518.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4DP63@85009|Propionibacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158390_k127_196352_6	1120950.KB892708_gene4274	2.305e-66	232.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4DQ7Y@85009|Propionibacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158390_k127_196352_5	44060.JODL01000006_gene1462	4.536e-73	252.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158390_k127_196352_3	1120950.KB892708_gene4271	8.725e-127	409.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4DN3U@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158390_k127_196352_4	446466.Cfla_1792	7.136e-85	285.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4F231@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158390_k127_196352_8	446466.Cfla_1790	1.968e-45	170.0	COG0494@1|root,COG0494@2|Bacteria,2IPJ3@201174|Actinobacteria,4F1AR@85016|Cellulomonadaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_196352_2	1463825.JNXC01000022_gene534	1.502e-138	441.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4DXUJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158390_k127_1967621_10	1120950.KB892742_gene2956	8.91e-27	115.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4DQ7D@85009|Propionibacteriales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158390_k127_1967621_7	351607.Acel_1040	6.551e-87	292.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria,4EVQ5@85013|Frankiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158390_k127_1967621_4	1463917.JODC01000007_gene7463	1.828e-115	391.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_1967621_1	351607.Acel_1042	3.142e-226	708.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4ESKE@85013|Frankiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_1967621_2	1463917.JODC01000007_gene7465	1.433e-169	537.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158390_k127_1967621_3	1463917.JODC01000007_gene7466	1.836e-147	474.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	-	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158390_k127_1967621_0	351607.Acel_1043	3.233e-253	786.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,4ESAX@85013|Frankiales	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_1967621_8	1079986.JH164864_gene6610	1.489e-75	261.0	COG3620@1|root,COG3837@1|root,COG3620@2|Bacteria,COG3837@2|Bacteria,2I4X7@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158390_k127_1967621_6	97096.XP_007790920.1	3.696e-99	346.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158390_k127_1967621_11	266779.Meso_3137	0.0002286	54.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,43HSH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_1967621_5	97096.XP_007790920.1	1.828e-114	390.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158390_k127_1967621_9	1231391.AMZF01000020_gene2008	4.171e-36	143.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_1968008_10	211114.JOEF01000011_gene5163	1.278e-74	252.0	COG4952@1|root,COG4952@2|Bacteria,2GK1Z@201174|Actinobacteria,4DZ7P@85010|Pseudonocardiales	201174|Actinobacteria	M	Isomerase	rhaI	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,RhaA
SRR25158390_k127_1968008_11	285535.JOEY01000025_gene9725	8.784e-64	226.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria	201174|Actinobacteria	IQ	Rhamnulose-1-phosphate aldolase alcohol dehydrogenase	rhaD	-	1.1.1.1,1.1.1.140,4.1.2.19	ko:K00001,ko:K00068,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R05607,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short_C2
SRR25158390_k127_1968008_18	1463825.JNXC01000009_gene1423	2.195e-44	166.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4DXBR@85010|Pseudonocardiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_1968008_1	1120949.KB903294_gene4391	5.75e-184	588.0	COG2905@1|root,COG2905@2|Bacteria,2I1DR@201174|Actinobacteria,4DI5N@85008|Micromonosporales	201174|Actinobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF294,DUF294_C
SRR25158390_k127_1968008_13	1298880.AUEV01000003_gene3384	2.449e-58	212.0	COG0542@1|root,COG0542@2|Bacteria,2IRV0@201174|Actinobacteria	201174|Actinobacteria	O	Clp domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR25158390_k127_1968008_22	1289387.AUKW01000018_gene2138	1.099e-25	108.0	2E3V5@1|root,32YSE@2|Bacteria,2GQM1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23,Sigma70_r4_2
SRR25158390_k127_1968008_8	1206735.BAGG01000058_gene2371	1.273e-83	282.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4FTW3@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_1968008_4	208439.AJAP_18985	7.026e-158	511.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DYZC@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_1968008_14	211114.JOEF01000036_gene1791	1.542e-53	190.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4E58S@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_1968008_6	1123024.AUII01000001_gene3039	3.226e-102	336.0	COG3832@1|root,COG3832@2|Bacteria,2IE7C@201174|Actinobacteria,4E3Y2@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_1968008_19	1123024.AUII01000001_gene3040	2.075e-40	153.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1968008_20	1120950.KB892720_gene1837	2.166e-39	149.0	2C2H7@1|root,32Z8Q@2|Bacteria,2I8BX@201174|Actinobacteria,4DSKJ@85009|Propionibacteriales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_1968008_7	443218.AS9A_2466	2.869e-84	286.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,236W6@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_1968008_0	653045.Strvi_2141	3.368e-273	859.0	COG0514@1|root,COG1040@1|root,COG0514@2|Bacteria,COG1040@2|Bacteria,2GJSS@201174|Actinobacteria	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
SRR25158390_k127_1968008_12	1122622.ATWJ01000002_gene831	9.292e-61	216.0	COG0705@1|root,COG0705@2|Bacteria,2HCGE@201174|Actinobacteria,4FIQB@85021|Intrasporangiaceae	201174|Actinobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158390_k127_1968008_24	1123319.AUBE01000008_gene3790	7.641e-09	63.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR25158390_k127_1968008_23	1121020.JIAG01000002_gene689	3.056e-18	86.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,1WA2V@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1968008_16	1236902.ANAS01000004_gene3555	2.677e-51	191.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4EQVJ@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_1968008_17	1122611.KB904007_gene7914	1.152e-44	164.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4EKB2@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_1968008_2	926564.KI911765_gene4541	4.637e-175	560.0	COG3103@1|root,COG4991@2|Bacteria,2GJE2@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRR25158390_k127_1968008_15	1894.JOER01000081_gene6235	6.254e-52	198.0	COG0501@1|root,COG0501@2|Bacteria,2GTHQ@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
SRR25158390_k127_1968008_3	1380354.JIAN01000005_gene2234	5.195e-175	569.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4F1XG@85016|Cellulomonadaceae	201174|Actinobacteria	M	PFAM penicillin-binding protein transpeptidase	pbp2B	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158390_k127_1968008_5	555088.DealDRAFT_0013	3.694e-153	500.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
SRR25158390_k127_1968008_21	479432.Sros_6673	1.542e-33	141.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria,4EH8I@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
SRR25158390_k127_1968008_25	1408254.T458_16980	0.0002032	51.0	COG1714@1|root,COG1714@2|Bacteria,1UWM8@1239|Firmicutes,4HBNM@91061|Bacilli,26X3P@186822|Paenibacillaceae	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_1968008_9	1123320.KB889640_gene4451	1.873e-82	276.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,DUF1116,Ligase_CoA
SRR25158390_k127_1970746_0	471852.Tcur_4689	0.0	1628.0	COG0714@1|root,COG0714@2|Bacteria,2GNQ8@201174|Actinobacteria,4EFT2@85012|Streptosporangiales	201174|Actinobacteria	NT	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
SRR25158390_k127_1970746_1	1463825.JNXC01000001_gene5955	5.403e-262	822.0	COG2268@1|root,COG2268@2|Bacteria,2GKB2@201174|Actinobacteria,4E2FC@85010|Pseudonocardiales	201174|Actinobacteria	S	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158390_k127_1970746_6	443218.AS9A_4169	5.168e-47	176.0	2A865@1|root,315GV@2|Bacteria,2IN68@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
SRR25158390_k127_1970746_12	2074.JNYD01000011_gene45	4.992e-22	105.0	2E40M@1|root,32YXE@2|Bacteria,2GRE0@201174|Actinobacteria,4EBW0@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1970746_10	1229203.KI301992_gene2169	7.662e-32	132.0	2E36U@1|root,32Y6I@2|Bacteria,2IM2G@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1416)	sseC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1416
SRR25158390_k127_1970746_2	479435.Kfla_0983	1.52e-155	495.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4DPRJ@85009|Propionibacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158390_k127_1970746_8	67352.JODS01000070_gene2258	9.273e-42	158.0	2AN8T@1|root,327DN@2|Bacteria,2I81P@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158390_k127_1970746_9	471852.Tcur_0600	1.271e-34	139.0	COG0526@1|root,COG0526@2|Bacteria,2IKMI@201174|Actinobacteria,4EK0E@85012|Streptosporangiales	201174|Actinobacteria	CO	Thioredoxin	thiX	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
SRR25158390_k127_1970746_11	66377.JOBH01000001_gene1661	2.288e-27	124.0	COG5662@1|root,COG5662@2|Bacteria,2GNCC@201174|Actinobacteria	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_1970746_5	1120950.KB892777_gene734	4.553e-60	215.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4DR2Y@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	sigL	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_1970746_3	1122611.KB903970_gene2620	1.515e-109	359.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4EI8P@85012|Streptosporangiales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158390_k127_1970746_4	471852.Tcur_0594	6.269e-86	294.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4EHNC@85012|Streptosporangiales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_1970746_7	105425.BBPL01000010_gene2178	7.892e-47	173.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,2NGAT@228398|Streptacidiphilus	201174|Actinobacteria	P	Polyphosphate kinase middle domain	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158390_k127_1981686_1	2074.JNYD01000025_gene574	9.866e-58	216.0	COG1840@1|root,COG1840@2|Bacteria,2GUG5@201174|Actinobacteria	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158390_k127_1981686_0	1380386.JIAW01000030_gene3590	2.03e-91	310.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2392Z@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1,SBP_bac_6
SRR25158390_k127_1982123_0	1906.SFRA_16800	5.798e-101	338.0	COG2807@1|root,COG2807@2|Bacteria,2I37C@201174|Actinobacteria	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1982123_1	1306174.JODP01000024_gene4098	2.522e-74	265.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria	201174|Actinobacteria	L	ErfK YbiS YcfS YnhG family protein	lppS	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158390_k127_1990613_1	1137269.AZWL01000001_gene5497	9.581e-144	467.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_1990613_4	446468.Ndas_2838	2.337e-33	131.0	2E53A@1|root,32ZWE@2|Bacteria,2GRGF@201174|Actinobacteria	201174|Actinobacteria	S	YrhK-like protein	yrhK	-	-	-	-	-	-	-	-	-	-	-	YrhK
SRR25158390_k127_1990613_3	743718.Isova_1033	7.187e-109	359.0	COG3279@1|root,COG3279@2|Bacteria,2HUIC@201174|Actinobacteria,4F5TI@85017|Promicromonosporaceae	201174|Actinobacteria	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158390_k127_1990613_2	1122602.ATXP01000012_gene1731	1.185e-112	378.0	COG3275@1|root,COG3275@2|Bacteria,2GJD4@201174|Actinobacteria,1W8CN@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_3,HATPase_c,His_kinase
SRR25158390_k127_1990613_0	743718.Isova_1035	1.479e-233	731.0	COG4147@1|root,COG4147@2|Bacteria,2GM3H@201174|Actinobacteria,4F5YZ@85017|Promicromonosporaceae	201174|Actinobacteria	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158390_k127_2018750_0	928724.SacglDRAFT_03063	2.367e-185	586.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4E1EE@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_2018750_10	710696.Intca_0857	1.53e-78	269.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4FHSY@85021|Intrasporangiaceae	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158390_k127_2018750_3	1122622.ATWJ01000009_gene3207	5.365e-147	486.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4FE72@85021|Intrasporangiaceae	201174|Actinobacteria	I	Long-chain fatty acid--CoA ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_2018750_12	1120950.KB892775_gene1189	3.977e-70	241.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4DRDV@85009|Propionibacteriales	201174|Actinobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158390_k127_2018750_9	446470.Snas_2021	3.357e-79	275.0	COG0177@1|root,COG0177@2|Bacteria,2GNYB@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018750_14	1298863.AUEP01000011_gene635	6.871e-42	158.0	COG1158@1|root,COG1158@2|Bacteria,2IKUK@201174|Actinobacteria,4DR4P@85009|Propionibacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018750_16	1298880.AUEV01000002_gene1624	8.413e-07	57.0	2B6XB@1|root,31ZX9@2|Bacteria,2IRX1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018750_8	1146883.BLASA_1744	1.756e-91	316.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4ETZ3@85013|Frankiales	201174|Actinobacteria	L	Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158390_k127_2018750_5	100226.SCO0895	2.014e-110	366.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_2018750_2	543632.JOJL01000027_gene2748	4.779e-157	501.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4D8KB@85008|Micromonosporales	201174|Actinobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158390_k127_2018750_1	263358.VAB18032_20890	3.481e-173	554.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,4DBZH@85008|Micromonosporales	201174|Actinobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158390_k127_2018750_11	1206732.BAGD01000054_gene2031	1.201e-75	260.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4FUXC@85025|Nocardiaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_2018750_6	420324.KI912029_gene247	1.63e-102	339.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,1JSUJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158390_k127_2018750_15	479435.Kfla_0244	1.734e-11	65.0	2EK8X@1|root,33DZ6@2|Bacteria,2GWJW@201174|Actinobacteria,4DSK4@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018750_4	247156.NFA_24130	1.503e-112	374.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4FWPF@85025|Nocardiaceae	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_2018750_13	882086.SacxiDRAFT_1162	6.556e-43	162.0	2DWVW@1|root,34251@2|Bacteria,2H760@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018750_7	408672.NBCG_02480	1.695e-93	310.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DN4M@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	yghA	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_2036024_3	749927.AMED_0325	8.078e-26	112.0	COG0645@1|root,COG0645@2|Bacteria,2I4UW@201174|Actinobacteria,4E5YW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33,CPT
SRR25158390_k127_2036024_4	1120950.KB892761_gene5809	1.043e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4DQA8@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
SRR25158390_k127_2036024_5	1120950.KB892761_gene5809	5.756e-06	52.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4DQA8@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
SRR25158390_k127_2036024_0	1298863.AUEP01000003_gene3128	6.226e-129	417.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4DTTG@85009|Propionibacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2036024_1	1172179.AUKV01000009_gene4409	1.679e-39	157.0	COG0842@1|root,COG0842@2|Bacteria,2HDDD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2040483_4	469371.Tbis_0415	1.028e-123	405.0	COG0318@1|root,COG2030@1|root,COG0318@2|Bacteria,COG2030@2|Bacteria,2GIUC@201174|Actinobacteria,4DZX5@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Lactamase_B
SRR25158390_k127_2040483_9	1121945.ATXS01000016_gene366	2.452e-47	181.0	COG0596@1|root,arCOG01648@2157|Archaea,2XUNG@28890|Euryarchaeota,23SVU@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	catD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158390_k127_2040483_7	1246995.AFR_13055	1.493e-102	339.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4DA2S@85008|Micromonosporales	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158390_k127_2040483_3	408672.NBCG_03975	6.219e-171	546.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	phaZ	-	3.1.1.75	ko:K03932,ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	CE1	-	Esterase_phd
SRR25158390_k127_2040483_6	1206744.BAGL01000038_gene512	7e-105	353.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,2GNNG@201174|Actinobacteria,4FU68@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
SRR25158390_k127_2040483_8	44060.JODL01000004_gene2450	5.715e-80	280.0	2A4ZY@1|root,30TN1@2|Bacteria,2GMC5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2040483_1	1122609.AUGT01000013_gene4166	2.895e-200	632.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4DNPF@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_2040483_5	1043205.AFYF01000056_gene2643	1.603e-117	383.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,4FFHE@85021|Intrasporangiaceae	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158390_k127_2040483_0	1463856.JOHY01000011_gene6890	2.014e-228	723.0	COG1109@1|root,COG1109@2|Bacteria,2GJ3Q@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pmmB	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158390_k127_2040483_10	1463845.JOIG01000007_gene707	4.705e-22	105.0	COG0515@1|root,COG0515@2|Bacteria,2IKPQ@201174|Actinobacteria	201174|Actinobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
SRR25158390_k127_2040483_11	1463845.JOIG01000007_gene707	4.399e-08	63.0	COG0515@1|root,COG0515@2|Bacteria,2IKPQ@201174|Actinobacteria	201174|Actinobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
SRR25158390_k127_2040483_2	469371.Tbis_3117	1.775e-193	619.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158390_k127_2040483_12	1040987.AZUY01000003_gene3611	7.84e-07	53.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,43HUM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158390_k127_2041677_6	266117.Rxyl_0363	2.775e-70	242.0	COG0683@1|root,COG0683@2|Bacteria,2I8ME@201174|Actinobacteria,4CQWB@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_2041677_3	266117.Rxyl_0362	2.451e-97	332.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4CQ8M@84995|Rubrobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_2041677_2	266117.Rxyl_0361	9.219e-116	382.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_2041677_5	266117.Rxyl_0360	1.139e-83	301.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CPJW@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_2041677_4	266117.Rxyl_0359	1.872e-89	300.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CRUA@84995|Rubrobacteria	84995|Rubrobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_2041677_0	675635.Psed_4198	1.549e-175	561.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DZ1Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158390_k127_2041677_1	1283287.KB822578_gene2324	4.203e-168	541.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4DV93@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158390_k127_2044084_2	235985.BBPN01000003_gene4709	2.889e-136	453.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,2NF4F@228398|Streptacidiphilus	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
SRR25158390_k127_2044084_4	1192034.CAP_8069	1.772e-90	309.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_2044084_0	269800.Tfu_1353	2.111e-203	643.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EHQR@85012|Streptosporangiales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158390_k127_2044084_9	585531.HMPREF0063_12096	8.15e-28	114.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,4DRQJ@85009|Propionibacteriales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRR25158390_k127_2044084_7	1033730.CAHG01000017_gene2444	1.653e-40	153.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4DUJI@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158390_k127_2044084_6	408672.NBCG_04268	8.59e-54	191.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria,4DWYI@85009|Propionibacteriales	201174|Actinobacteria	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_2044084_1	1120950.KB892793_gene2360	3.961e-163	520.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4DP41@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158390_k127_2044084_3	394.NGR_c30110	6.335e-113	374.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2TV1G@28211|Alphaproteobacteria,4BD7E@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158390_k127_2044084_5	1353531.AZNX01000005_gene3661	6.416e-83	280.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2VEV2@28211|Alphaproteobacteria,4BGIF@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2044084_8	1312959.KI914655_gene666	2.665e-38	152.0	2DBXI@1|root,2ZBQ3@2|Bacteria,2GJN1@201174|Actinobacteria,1W9VX@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
SRR25158390_k127_2044084_10	1122182.KB903825_gene624	2.083e-14	78.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria,4DMC6@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_2052716_4	68170.KL590535_gene3955	0.0001242	44.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria,4DYBP@85010|Pseudonocardiales	201174|Actinobacteria	M	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
SRR25158390_k127_2052716_0	1157638.KB892167_gene4587	3.149e-115	382.0	COG2072@1|root,COG2072@2|Bacteria,2GMDH@201174|Actinobacteria	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158390_k127_2052716_2	1114959.SZMC14600_08989	1.705e-54	204.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4EBP1@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_2052716_1	58344.JOEL01000001_gene350	2.09e-60	213.0	COG2368@1|root,COG2368@2|Bacteria,2GKIQ@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
SRR25158390_k127_205688_10	935948.KE386494_gene107	7.892e-47	173.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,25MJ2@186801|Clostridia,42I8Z@68295|Thermoanaerobacterales	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
SRR25158390_k127_205688_8	273068.TTE1936	4.685e-54	202.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,42HXI@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10122,ko:K17243	ko02010,map02010	M00197,M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.20,3.A.1.1.39	-	-	BPD_transp_1
SRR25158390_k127_205688_3	266940.Krad_0078	8.611e-126	427.0	COG3507@1|root,COG3507@2|Bacteria,2GIYA@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43,RicinB_lectin_2
SRR25158390_k127_205688_0	1968.JOEV01000010_gene1668	1.277e-242	758.0	COG3534@1|root,COG3534@2|Bacteria,2GMAK@201174|Actinobacteria	201174|Actinobacteria	G	alpha-L-arabinofuranosidase	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SRR25158390_k127_205688_5	1382356.JQMP01000004_gene192	1.904e-76	267.0	COG1414@1|root,COG1414@2|Bacteria,2G8KK@200795|Chloroflexi,27Z1R@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_205688_4	469383.Cwoe_5124	2.825e-117	384.0	COG0826@1|root,COG0826@2|Bacteria,2GKAK@201174|Actinobacteria,4CSIM@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
SRR25158390_k127_205688_1	1380370.JIBA01000010_gene2381	3.723e-175	555.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria,4FEJN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158390_k127_205688_9	1163409.UUA_01060	1.184e-53	195.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,1RYNR@1236|Gammaproteobacteria,1X7BP@135614|Xanthomonadales	135614|Xanthomonadales	S	NAD(P)H-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
SRR25158390_k127_205688_6	1122182.KB903825_gene862	2.024e-67	235.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,4DDA7@85008|Micromonosporales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_205688_11	479432.Sros_1741	3.997e-45	168.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4EJ5Y@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_205688_7	1121927.GOHSU_27_00050	4.282e-59	209.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4GB5K@85026|Gordoniaceae	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158390_k127_205688_2	1032480.MLP_00570	1.579e-158	529.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DWFW@85009|Propionibacteriales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_2077342_8	136273.GY22_14610	6.154e-08	56.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158390_k127_2077342_2	298654.FraEuI1c_6907	1.831e-128	416.0	COG2159@1|root,COG2159@2|Bacteria,2I9E4@201174|Actinobacteria,4EUN7@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158390_k127_2077342_5	2074.JNYD01000008_gene1048	2.82e-37	162.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158390_k127_2077342_0	1123024.AUII01000053_gene167	1.019e-208	657.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158390_k127_2077342_4	675635.Psed_1625	5.222e-78	265.0	COG2044@1|root,COG2044@2|Bacteria,2GJQS@201174|Actinobacteria,4DYQM@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158390_k127_2077342_3	1123024.AUII01000034_gene2674	1.05e-125	415.0	COG0438@1|root,COG0438@2|Bacteria,2GKX4@201174|Actinobacteria,4E2H9@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2077342_1	1123024.AUII01000034_gene2675	2.803e-174	565.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria,4E87Z@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158390_k127_2077342_7	1123024.AUII01000053_gene168	1.176e-20	94.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4E9CR@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158390_k127_2083015_0	1121272.KB903261_gene6243	4.574e-162	522.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4D9X6@85008|Micromonosporales	201174|Actinobacteria	S	Transporter associated domain	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_2083015_1	644283.Micau_0110	7.837e-152	486.0	COG1253@1|root,COG1253@2|Bacteria,2GJ8X@201174|Actinobacteria,4DB67@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function DUF21	ytfL	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
SRR25158390_k127_2083015_2	35754.JNYJ01000066_gene8727	8.526e-73	258.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4D8YR@85008|Micromonosporales	201174|Actinobacteria	M	NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158390_k127_2083015_3	1120949.KB903295_gene2512	9.735e-34	136.0	COG1520@1|root,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria,4D8TV@85008|Micromonosporales	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
SRR25158390_k127_2096780_0	1120950.KB892762_gene5449	0.0	1184.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4DN7K@85009|Propionibacteriales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158390_k127_2096780_1	1120950.KB892762_gene5450	3.829e-166	533.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,4DNCS@85009|Propionibacteriales	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
SRR25158390_k127_2099163_1	314256.OG2516_16024	4.08e-37	148.0	COG1172@1|root,COG1172@2|Bacteria,1MX1K@1224|Proteobacteria,2TUYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158390_k127_2099163_0	1122214.AQWH01000008_gene1566	2.886e-57	222.0	COG1879@1|root,COG1879@2|Bacteria,1N1FF@1224|Proteobacteria,2UDI7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158390_k127_2105393_5	136273.GY22_14385	1.339e-81	286.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158390_k127_2105393_2	882083.SacmaDRAFT_2713	3.185e-92	325.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,4E9GC@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158390_k127_2105393_3	500153.JOEK01000021_gene23	1.812e-86	293.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158390_k127_2105393_4	500153.JOEK01000021_gene22	1.262e-81	280.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158390_k127_2105393_7	591158.SSMG_03663	3.017e-56	206.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_2105393_1	1144310.PMI07_005444	2.474e-127	415.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,4BCRD@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158390_k127_2105393_8	1437608.BBIA_2445	5.606e-45	181.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4D00I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_IclR
SRR25158390_k127_2105393_0	591158.SSMG_03563	3.095e-145	494.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K18230	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.120	-	-	ABC_tran,ABC_tran_Xtn
SRR25158390_k127_2105393_6	1463917.JODC01000007_gene7461	1.059e-57	205.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158390_k127_212426_0	1464048.JNZS01000017_gene3586	7.053e-226	711.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4DB0E@85008|Micromonosporales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158390_k127_212426_5	935839.JAGJ01000032_gene35	2.277e-112	372.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4F44Q@85017|Promicromonosporaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158390_k127_212426_7	479432.Sros_1735	3.132e-76	262.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4EH8W@85012|Streptosporangiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158390_k127_212426_2	1122611.KB903996_gene7507	8.579e-157	512.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EFP2@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158390_k127_212426_10	2002.JOEQ01000024_gene66	5.66e-23	101.0	COG2188@1|root,COG2188@2|Bacteria,2GZ7D@201174|Actinobacteria,4EQ5C@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
SRR25158390_k127_212426_6	2074.JNYD01000003_gene3676	1.344e-90	306.0	COG2197@1|root,COG2197@2|Bacteria,2GN29@201174|Actinobacteria,4DY2A@85010|Pseudonocardiales	201174|Actinobacteria	KT	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_212426_4	211114.JOEF01000001_gene7293	7.531e-118	395.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4DZVK@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR25158390_k127_212426_9	675635.Psed_0652	3.394e-65	237.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4E1B0@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158390_k127_212426_3	479435.Kfla_3500	1.915e-139	448.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DPDF@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_212426_8	1273125.Rrhod_3500	3.057e-65	243.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4FVR7@85025|Nocardiaceae	201174|Actinobacteria	O	Redoxin	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158390_k127_212426_1	446470.Snas_1683	4.582e-218	698.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_2129913_2	1122182.KB903836_gene4706	1.116e-44	172.0	COG2508@1|root,COG2508@2|Bacteria,2GKV3@201174|Actinobacteria,4DBJB@85008|Micromonosporales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158390_k127_2129913_0	479435.Kfla_4234	1.918e-162	539.0	28KG3@1|root,2ZA20@2|Bacteria,2GNQP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
SRR25158390_k127_2129913_4	1464048.JNZS01000007_gene4575	2.168e-10	68.0	2BSTK@1|root,32MX1@2|Bacteria,2HE7G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2129913_3	356851.JOAN01000002_gene922	2.256e-37	151.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Thioredoxin
SRR25158390_k127_2129913_1	558169.AGAV01000017_gene1079	2.186e-144	489.0	COG1434@1|root,COG2936@1|root,COG1434@2|Bacteria,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli	91061|Bacilli	E	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline	pepX	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,PepX_N,Peptidase_S15
SRR25158390_k127_2130919_2	469383.Cwoe_3954	1.007e-79	273.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158390_k127_2130919_3	1120917.AQXM01000046_gene25	5.434e-69	244.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,1W88X@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2130919_8	263358.VAB18032_20115	1.598e-44	180.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4DB92@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_2130919_6	479434.Sthe_0621	7.738e-54	203.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158390_k127_2130919_9	1045009.AFXQ01000004_gene1995	1.808e-06	58.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,1WA2V@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2130919_4	1121011.AUCB01000034_gene893	1.773e-65	237.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2130919_5	1120950.KB892742_gene3018	2.357e-64	224.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158390_k127_2130919_7	1120950.KB892742_gene3016	4.391e-51	186.0	2BM8T@1|root,32FSI@2|Bacteria,2IG06@201174|Actinobacteria,4DR8K@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA adenosine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2130919_1	469371.Tbis_3539	3.446e-100	340.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4DZ16@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158390_k127_2130919_0	1179773.BN6_15510	3.297e-140	456.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158390_k127_2131843_0	1123320.KB889607_gene9525	1.943e-148	485.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	eryCIV	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158390_k127_2135128_2	1120950.KB892768_gene5273	1.49e-240	757.0	COG4799@1|root,COG4799@2|Bacteria,2I16G@201174|Actinobacteria,4DNAY@85009|Propionibacteriales	201174|Actinobacteria	I	Malonate decarboxylase gamma subunit (MdcE)	accD6	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009317,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:1901575,GO:1901576,GO:1902494	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18472	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04386	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158390_k127_2135128_5	1206101.AZXC01000001_gene4365	5.11e-173	552.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158390_k127_2135128_19	479435.Kfla_2566	1.131e-33	134.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,4DRYW@85009|Propionibacteriales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158390_k127_2135128_7	479435.Kfla_2567	4.618e-136	443.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4DP78@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158390_k127_2135128_4	479435.Kfla_2568	3.401e-178	566.0	COG0331@1|root,COG0511@1|root,COG0331@2|Bacteria,COG0511@2|Bacteria,2GME0@201174|Actinobacteria,4DPZC@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl transferase domain	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158390_k127_2135128_10	1123322.KB904724_gene2091	8.04e-129	424.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria	201174|Actinobacteria	QT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158390_k127_2135128_17	1068980.ARVW01000001_gene7049	7.704e-61	218.0	COG1309@1|root,COG1309@2|Bacteria,2GNH0@201174|Actinobacteria,4E5UR@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_2135128_9	1463825.JNXC01000027_gene3227	1.102e-132	431.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJX@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_2135128_11	1121272.KB903291_gene3442	3.105e-109	366.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DB65@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2135128_14	591159.ACEZ01000226_gene1046	1.05e-85	289.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158390_k127_2135128_0	1121272.KB903253_gene6837	0.0	1440.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DABZ@85008|Micromonosporales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158390_k127_2135128_21	1206726.BAFV01000003_gene227	4.989e-23	99.0	COG2905@1|root,COG2905@2|Bacteria,2GQMA@201174|Actinobacteria,4G3WF@85025|Nocardiaceae	201174|Actinobacteria	T	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158390_k127_2135128_18	1120950.KB892768_gene5259	1.305e-52	189.0	2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158390_k127_2135128_20	1394178.AWOO02000051_gene6025	8.835e-25	106.0	2E5NJ@1|root,330DC@2|Bacteria,2IREF@201174|Actinobacteria,4EK35@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2135128_16	1133849.O3I_013275	5.106e-68	239.0	COG3576@1|root,COG3576@2|Bacteria,2I3RW@201174|Actinobacteria,4G0JU@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2135128_6	1306174.JODP01000009_gene6458	2.915e-138	450.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158390_k127_2135128_15	471852.Tcur_1674	2.223e-70	246.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4EH3Z@85012|Streptosporangiales	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158390_k127_2135128_13	67352.JODS01000001_gene596	2.964e-93	319.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria	201174|Actinobacteria	GL	phosphoglycerate mutase	-	-	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR25158390_k127_2135128_8	469371.Tbis_3489	2.344e-135	443.0	COG0389@1|root,COG0389@2|Bacteria,2GKHC@201174|Actinobacteria,4DZPZ@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158390_k127_2135128_12	1463903.JOIZ01000007_gene3903	2.123e-103	345.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria	201174|Actinobacteria	S	RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
SRR25158390_k127_2135128_3	1120950.KB892746_gene3508	1.57e-204	642.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DPAI@85009|Propionibacteriales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158390_k127_2135128_22	369723.Strop_4388	0.0002416	44.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4DAVS@85008|Micromonosporales	201174|Actinobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158390_k127_2135128_1	405948.SACE_4744	3.233e-247	779.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4DX7E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR25158390_k127_2165845_36	67356.KL575607_gene8860	4.856e-09	58.0	2D0CU@1|root,32T8C@2|Bacteria,2GNI4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2165845_25	1123024.AUII01000008_gene1770	1.671e-57	208.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria,4EBAP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2165845_26	1463856.JOHY01000023_gene1930	3.111e-36	143.0	COG2146@1|root,COG2146@2|Bacteria,2IKSY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,TAT_signal
SRR25158390_k127_2165845_33	1043205.AFYF01000045_gene2925	1.348e-20	99.0	2ET1V@1|root,33KK0@2|Bacteria,2GZYR@201174|Actinobacteria,4FI7B@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
SRR25158390_k127_2165845_29	367299.JOEE01000001_gene1666	4.197e-28	117.0	COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria,4FHYN@85021|Intrasporangiaceae	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SRR25158390_k127_2165845_8	196162.Noca_0658	1.551e-119	390.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_2165845_9	1123023.JIAI01000006_gene140	7.587e-117	383.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4DXUE@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2165845_4	1120950.KB892741_gene2633	1.895e-148	487.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4DP7U@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_2165845_31	330084.JNYZ01000009_gene6465	9.974e-23	104.0	2E6IT@1|root,3315W@2|Bacteria,2GR2R@201174|Actinobacteria,4E6J5@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR25158390_k127_2165845_12	882083.SacmaDRAFT_5528	4.726e-113	374.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4DZE5@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158390_k127_2165845_11	1068980.ARVW01000001_gene3510	3.999e-113	370.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4DZJW@85010|Pseudonocardiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_2165845_35	1121926.AXWO01000003_gene860	2.754e-11	69.0	COG1610@1|root,COG1610@2|Bacteria	2|Bacteria	S	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158390_k127_2165845_17	1449976.KALB_7485	3.055e-94	312.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4DZBZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
SRR25158390_k127_2165845_28	208439.AJAP_26370	7.119e-29	129.0	COG2852@1|root,COG2852@2|Bacteria,2I3TW@201174|Actinobacteria,4EFAU@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2165845_16	1449976.KALB_7484	1.456e-97	333.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DZ70@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl transferases group 1	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2165845_2	43354.JOIJ01000003_gene3878	9.235e-169	545.0	COG1543@1|root,COG1543@2|Bacteria,2GKTI@201174|Actinobacteria,4DZYG@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158390_k127_2165845_21	1120950.KB892741_gene2641	4.677e-69	242.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4DUFI@85009|Propionibacteriales	201174|Actinobacteria	H	Methyltransferase domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158390_k127_2165845_13	1193181.BN10_570011	4.592e-103	341.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4FEFQ@85021|Intrasporangiaceae	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158390_k127_2165845_6	1120950.KB892741_gene2646	1.016e-134	435.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DNKA@85009|Propionibacteriales	201174|Actinobacteria	C	electron transfer flavoprotein, alpha subunit	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158390_k127_2165845_19	1120950.KB892801_gene1800	2.825e-86	293.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria,4DRRF@85009|Propionibacteriales	201174|Actinobacteria	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158390_k127_2165845_10	263358.VAB18032_10275	2.999e-115	387.0	COG5002@1|root,COG5002@2|Bacteria,2I3U8@201174|Actinobacteria,4D9HY@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_2165845_15	65497.JODV01000002_gene4192	7.434e-99	328.0	COG0745@1|root,COG0745@2|Bacteria,2GMVN@201174|Actinobacteria,4E0AP@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2165845_30	1445613.JALM01000076_gene165	2.073e-25	111.0	COG3416@1|root,COG3416@2|Bacteria,2GQP7@201174|Actinobacteria,4E7Z4@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2165845_3	1120950.KB892741_gene2649	1.407e-165	529.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4DNQT@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-V	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158390_k127_2165845_1	105422.BBPM01000002_gene5044	1.872e-179	568.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,2NHR7@228398|Streptacidiphilus	201174|Actinobacteria	J	tRNA methyl transferase	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158390_k127_2165845_18	1313172.YM304_30000	3.872e-92	319.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria	201174|Actinobacteria	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158390_k127_2165845_20	390989.JOEG01000012_gene3381	1.105e-76	268.0	COG1073@1|root,COG1073@2|Bacteria,2IC0U@201174|Actinobacteria,4DDBT@85008|Micromonosporales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_2165845_24	882086.SacxiDRAFT_0177	3.802e-63	232.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria,4E34Z@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_2165845_14	1120950.KB892741_gene2651	1.01e-102	355.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,4DN0J@85009|Propionibacteriales	201174|Actinobacteria	E	Methionine synthase, vitamin-B12 independent	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
SRR25158390_k127_2165845_0	266940.Krad_1315	2.736e-294	923.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158390_k127_2165845_34	1214101.BN159_3373	7.071e-15	76.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_2165845_27	1033730.CAHG01000012_gene2026	4.234e-34	136.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4DQU3@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20)	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_2165845_23	390989.JOEG01000006_gene808	1.67e-63	226.0	2BS0P@1|root,32M18@2|Bacteria,2HWUX@201174|Actinobacteria,4DKEX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2165845_32	1032480.MLP_23110	3.433e-21	98.0	2EG6R@1|root,339YM@2|Bacteria,2GX31@201174|Actinobacteria,4DSMY@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR25158390_k127_2165845_22	479435.Kfla_5793	4.985e-64	224.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4DR1C@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	padR	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158390_k127_2165845_7	44060.JODL01000031_gene1766	9.324e-125	407.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria	201174|Actinobacteria	D	Ribonuclease bn	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158390_k127_2165845_5	1449355.JQNR01000005_gene4553	6.692e-140	453.0	COG0154@1|root,COG5001@1|root,COG0154@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158390_k127_2200458_0	1463887.KL590019_gene8037	7.938e-113	376.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2200458_1	1463853.JOHW01000001_gene6330	8.923e-71	246.0	COG1414@1|root,COG1414@2|Bacteria,2GMEA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	sdrB	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158390_k127_2200458_2	479433.Caci_1485	5.233e-51	185.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria	201174|Actinobacteria	K	asnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_2200458_3	478801.Ksed_10550	6.134e-46	173.0	COG3185@1|root,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,1ZWCN@145357|Dermacoccaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	hpd	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158390_k127_2205333_1	1122138.AQUZ01000056_gene6945	6.365e-134	429.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4DNGW@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158390_k127_2205333_0	479435.Kfla_6293	4.19e-238	740.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4DPP6@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158390_k127_2205333_2	1236902.ANAS01000019_gene4157	2.241e-91	306.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4EHWV@85012|Streptosporangiales	201174|Actinobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158390_k127_2205501_0	1906.SFRA_24005	2.615e-237	746.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD4	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2205501_2	1120950.KB892812_gene7005	1.769e-96	323.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4DNQW@85009|Propionibacteriales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158390_k127_2205501_3	1268303.RHODMAR_0448	2.672e-80	274.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,4FYYT@85025|Nocardiaceae	201174|Actinobacteria	P	TrkA-C domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158390_k127_2205501_1	1288079.AUKN01000007_gene1881	5.072e-160	517.0	COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria	201174|Actinobacteria	P	Potassium uptake protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158390_k127_2205501_4	1288083.AUKR01000021_gene1501	6.076e-28	116.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria	201174|Actinobacteria	P	Kef-type K transport systems	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
SRR25158390_k127_2207189_2	1174528.JH992893_gene5824	0.0007058	43.0	COG0642@1|root,COG2205@2|Bacteria,1G17B@1117|Cyanobacteria,1JJMS@1189|Stigonemataceae	1117|Cyanobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_2207189_1	525909.Afer_1576	6.964e-80	273.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2207189_0	378806.STAUR_7254	1.118e-94	325.0	COG4213@1|root,COG4213@2|Bacteria,1R4J2@1224|Proteobacteria,43B1Y@68525|delta/epsilon subdivisions,2X6G1@28221|Deltaproteobacteria,2Z3AX@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158390_k127_2213730_0	1122622.ATWJ01000012_gene1024	0.0	1049.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4FE8A@85021|Intrasporangiaceae	201174|Actinobacteria	EQ	Hydantoinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158390_k127_2213730_1	1448389.BAVQ01000083_gene97	7.36e-322	996.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158390_k127_2252267_1	526225.Gobs_3588	1.653e-23	111.0	2AR9G@1|root,31GJC@2|Bacteria,2GN9V@201174|Actinobacteria,4EWX7@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
SRR25158390_k127_2252267_0	58123.JOFJ01000004_gene1792	5.153e-24	104.0	COG1595@1|root,COG1595@2|Bacteria,2GP2X@201174|Actinobacteria,4EIZK@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_2272204_3	471856.Jden_1633	2.5e-24	105.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	2.3.2.29,2.5.1.18,3.8.1.2	ko:K00799,ko:K01560,ko:K21420	ko00361,ko00480,ko00625,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00625,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418	-	R03522,R05287,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11547,R11548,R11905	RC00004,RC00064,RC00069,RC00697,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
SRR25158390_k127_2272204_0	1306174.JODP01000002_gene5708	9.212e-187	587.0	COG1619@1|root,COG1619@2|Bacteria,2GNW5@201174|Actinobacteria	201174|Actinobacteria	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
SRR25158390_k127_2272204_2	391037.Sare_4062	7.535e-52	198.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4D9A2@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_2272204_1	1463820.JOGW01000005_gene3458	1.919e-68	236.0	2EGSG@1|root,33AIJ@2|Bacteria,2INAJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
SRR25158390_k127_228385_5	1120950.KB892741_gene2684	1.637e-116	381.0	2BYH3@1|root,2Z7SZ@2|Bacteria,2GMTF@201174|Actinobacteria,4DN7N@85009|Propionibacteriales	201174|Actinobacteria	S	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_228385_8	1120950.KB892708_gene4370	4.343e-79	283.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria,4DT8G@85009|Propionibacteriales	201174|Actinobacteria	E	Arginase family	-	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_228385_12	345341.KUTG_07418	7.711e-61	228.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria,4DY7U@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158390_k127_228385_4	1179773.BN6_07520	3.039e-131	441.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DYDC@85010|Pseudonocardiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158390_k127_228385_18	743718.Isova_1540	3.003e-14	81.0	2BUUD@1|root,32Q65@2|Bacteria,2I0NA@201174|Actinobacteria,4F4YH@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158390_k127_228385_0	469371.Tbis_0652	0.0	1025.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DZQT@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158390_k127_228385_9	67352.JODS01000014_gene5455	5.048e-72	247.0	COG0775@1|root,COG0775@2|Bacteria,2IMZ7@201174|Actinobacteria	201174|Actinobacteria	F	nucleosidase	-	-	3.2.2.1,3.2.2.9	ko:K01239,ko:K01243	ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230	M00034,M00609	R00194,R01245,R01273,R01401,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158390_k127_228385_16	479435.Kfla_1240	2.931e-28	117.0	2E4PN@1|root,32ZIA@2|Bacteria,2HZDV@201174|Actinobacteria,4DSB1@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_228385_7	1120950.KB892783_gene320	4.94e-99	329.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DQ1R@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_228385_6	1120950.KB892783_gene321	1.777e-116	389.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DNII@85009|Propionibacteriales	201174|Actinobacteria	T	PspC domain	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
SRR25158390_k127_228385_14	1048339.KB913029_gene2814	6.238e-46	184.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4EW85@85013|Frankiales	201174|Actinobacteria	KT	PFAM PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
SRR25158390_k127_228385_10	443218.AS9A_3074	1.824e-70	252.0	COG5340@1|root,COG5340@2|Bacteria,2H6VP@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_228385_13	1122622.ATWJ01000001_gene2572	3.389e-55	207.0	COG3187@1|root,COG3187@2|Bacteria,2I9ND@201174|Actinobacteria	201174|Actinobacteria	O	META domain	hslJ	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
SRR25158390_k127_228385_19	1169154.KB897778_gene3129	7.495e-09	69.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_228385_1	1048339.KB913029_gene2809	5.401e-273	846.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4ERBR@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158390_k127_228385_3	1386089.N865_18405	3.945e-169	549.0	COG1132@1|root,COG1132@2|Bacteria,2GJAP@201174|Actinobacteria,4FF0Q@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_228385_2	1122138.AQUZ01000058_gene3484	8.827e-213	697.0	COG1132@1|root,COG1132@2|Bacteria,2GJ8B@201174|Actinobacteria,4DNKK@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_228385_15	1089545.KB913037_gene4645	5.829e-30	121.0	COG4298@1|root,COG4298@2|Bacteria,2IQ7S@201174|Actinobacteria,4E5WN@85010|Pseudonocardiales	201174|Actinobacteria	S	yiaA/B two helix domain	-	-	-	-	-	-	-	-	-	-	-	-	YiaAB
SRR25158390_k127_228385_17	1101192.KB910516_gene3130	1.187e-25	117.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2UG54@28211|Alphaproteobacteria,1JUV6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158390_k127_228385_11	1121272.KB903249_gene1527	2.355e-67	241.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4D9SD@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_2286896_12	1042877.GQS_04320	1.232e-17	97.0	COG1361@1|root,COG1404@1|root,arCOG03610@1|root,arCOG00704@2157|Archaea,arCOG02089@2157|Archaea,arCOG03610@2157|Archaea,2XV8N@28890|Euryarchaeota,243CT@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S8 family	pls	GO:0005575,GO:0005623,GO:0031975,GO:0044464	-	-	-	-	-	-	-	-	-	-	CARDB,PPC,Peptidase_S8
SRR25158390_k127_2286896_14	1173024.KI912148_gene2700	4.593e-05	56.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1G04D@1117|Cyanobacteria,1JKHR@1189|Stigonemataceae	1117|Cyanobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PPC,Peptidase_S8
SRR25158390_k127_2286896_5	994479.GL877878_gene1211	8.314e-37	143.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4E5CC@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_2286896_4	1237500.ANBA01000017_gene1596	3.166e-91	308.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_2286896_2	369723.Strop_2973	1.344e-133	433.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4DMRH@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2286896_1	1120950.KB892764_gene5600	2.78e-164	526.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4DN5U@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158390_k127_2286896_3	1120950.KB892764_gene5601	4.502e-96	327.0	COG1670@1|root,COG1670@2|Bacteria,2GMDB@201174|Actinobacteria,4DQEE@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158390_k127_2286896_0	1120950.KB892764_gene5602	0.0	1253.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4DPEU@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158390_k127_2286896_7	656024.FsymDg_3077	1.627e-30	126.0	COG2337@1|root,COG2337@2|Bacteria,2GSJT@201174|Actinobacteria	201174|Actinobacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_2286896_11	1385518.N798_12590	4.173e-19	92.0	2DPN9@1|root,332RH@2|Bacteria,2IR7E@201174|Actinobacteria,4FHSZ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2286896_6	1120950.KB892764_gene5604	9.423e-33	137.0	COG1652@1|root,COG1652@2|Bacteria,2GQMU@201174|Actinobacteria,4DWVX@85009|Propionibacteriales	201174|Actinobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158390_k127_2286896_8	298655.KI912266_gene114	1.81e-29	130.0	2E4C6@1|root,32Z7Q@2|Bacteria,2GRH1@201174|Actinobacteria,4ETFH@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2286896_9	110319.CF8_0878	1.887e-28	117.0	COG3311@1|root,COG3311@2|Bacteria,2GR98@201174|Actinobacteria,4DS1Q@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_2286896_10	1146883.BLASA_4092	1.093e-25	115.0	2EMPV@1|root,33FCA@2|Bacteria,2I5I4@201174|Actinobacteria,4ETCU@85013|Frankiales	201174|Actinobacteria	S	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
SRR25158390_k127_2287486_3	28444.JODQ01000003_gene4759	4.387e-47	174.0	COG4106@1|root,COG4106@2|Bacteria,2I9QB@201174|Actinobacteria,4EFF6@85012|Streptosporangiales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_2287486_0	266940.Krad_3173	2.134e-125	405.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158390_k127_2287486_2	471852.Tcur_2891	7.157e-49	178.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4EJGT@85012|Streptosporangiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_2287486_1	1306406.ASHX01000001_gene3238	2.44e-124	409.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158390_k127_2287486_4	1122182.KB903813_gene2702	3.896e-42	158.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4DB60@85008|Micromonosporales	201174|Actinobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_5
SRR25158390_k127_2288920_10	1032480.MLP_34400	1.78e-40	156.0	COG1403@1|root,COG1403@2|Bacteria,2I9AH@201174|Actinobacteria,4DMZA@85009|Propionibacteriales	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_2288920_7	350058.Mvan_3112	4.02e-48	184.0	COG2267@1|root,COG2267@2|Bacteria,2I4FK@201174|Actinobacteria,23FD3@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_2288920_8	1380347.JNII01000005_gene3051	2.259e-46	181.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2GN4Z@201174|Actinobacteria,4EVJZ@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
SRR25158390_k127_2288920_1	1003195.SCAT_3820	1.141e-283	882.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158390_k127_2288920_4	196490.AUEZ01000037_gene2928	3.062e-67	257.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2TQQR@28211|Alphaproteobacteria,3JTWJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158390_k127_2288920_3	351607.Acel_0576	4.059e-92	316.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria	201174|Actinobacteria	S	protein containing SIS (Sugar isomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158390_k127_2288920_0	1120950.KB892759_gene6232	0.0	1180.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4DN9B@85009|Propionibacteriales	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158390_k127_2288920_2	1056816.JAFQ01000004_gene3168	2.327e-104	346.0	COG3315@1|root,COG3315@2|Bacteria,2GJIS@201174|Actinobacteria,4FXUK@85025|Nocardiaceae	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_2288920_9	1122138.AQUZ01000007_gene3204	2.267e-45	178.0	2DG3P@1|root,2ZUBI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2288920_6	1120950.KB892720_gene1807	8.121e-59	207.0	COG0748@1|root,COG0748@2|Bacteria,2I63J@201174|Actinobacteria	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2288920_5	1120950.KB892759_gene6234	6.013e-60	223.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4DQT5@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158390_k127_2288920_11	196162.Noca_3492	5.194e-21	96.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4DPH6@85009|Propionibacteriales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cyaA	GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009268,GO:0009628,GO:0009975,GO:0009987,GO:0010851,GO:0010854,GO:0010855,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0030234,GO:0031279,GO:0031406,GO:0033293,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098772,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1264	Ad_Cy_reg,Guanylate_cyc
SRR25158390_k127_2295784_3	404589.Anae109_3668	4.243e-157	513.0	COG2197@1|root,COG2197@2|Bacteria,1R03J@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_2295784_17	314345.SPV1_12380	6.042e-09	64.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_2295784_13	1380354.JIAN01000005_gene1655	1.188e-53	210.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_2295784_12	1231185.BAMP01000065_gene196	4.646e-54	218.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,43HMD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type oligopeptide transport system periplasmic component	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158390_k127_2295784_7	1121380.JNIW01000017_gene2949	4.021e-76	289.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
SRR25158390_k127_2295784_14	1120949.KB903304_gene6881	1.997e-29	122.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158390_k127_2295784_19	1189612.A33Q_0331	8.276e-08	63.0	2E3HM@1|root,32YG7@2|Bacteria,4NW2A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2295784_10	1120950.KB892823_gene555	3.084e-58	212.0	COG0421@1|root,COG0421@2|Bacteria,2I2TN@201174|Actinobacteria,4DRAK@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158390_k127_2295784_11	1172180.KB911775_gene5867	8.029e-57	207.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158390_k127_2295784_18	1463917.JODC01000008_gene3585	6.417e-08	56.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23
SRR25158390_k127_2295784_0	471852.Tcur_1080	8.156e-306	944.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,2GK6D@201174|Actinobacteria,4EG9D@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fum	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
SRR25158390_k127_2295784_1	479433.Caci_0201	5.813e-215	682.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158390_k127_2295784_15	479435.Kfla_5695	8.212e-26	113.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4DS5K@85009|Propionibacteriales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158390_k127_2295784_8	1298880.AUEV01000015_gene90	6.291e-72	246.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria	201174|Actinobacteria	S	Septum formation initiator family protein	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158390_k127_2295784_5	457425.XNR_2002	1.213e-106	353.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158390_k127_2295784_9	469383.Cwoe_5669	6.442e-68	237.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_2295784_4	110319.CF8_3160	1.156e-119	391.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4DNFH@85009|Propionibacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_2295784_2	1120950.KB892752_gene6183	2.07e-199	630.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DPIA@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_2295784_6	1169161.KB897724_gene5010	1.118e-102	349.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158390_k127_2305573_2	1123319.AUBE01000011_gene4439	5.449e-53	195.0	COG2706@1|root,COG2706@2|Bacteria,2GNMK@201174|Actinobacteria	201174|Actinobacteria	G	3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
SRR25158390_k127_2305573_3	1463856.JOHY01000012_gene3231	1.736e-43	162.0	2CC1Y@1|root,32TCV@2|Bacteria,2IQEP@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	wblA	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_2305573_0	1306174.JODP01000001_gene5356	2.942e-152	492.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_2305573_1	471852.Tcur_4924	4.977e-59	210.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4EGQR@85012|Streptosporangiales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_2309572_4	710696.Intca_3070	1.983e-30	121.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2I995@201174|Actinobacteria,4FITA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158390_k127_2309572_1	350058.Mvan_4110	1.555e-143	462.0	COG0167@1|root,COG0167@2|Bacteria,2GN1V@201174|Actinobacteria,236T5@1762|Mycobacteriaceae	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158390_k127_2309572_0	649831.L083_0171	3.214e-153	496.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4D8MY@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158390_k127_2309572_3	926560.KE387027_gene707	2.076e-65	234.0	COG1765@1|root,COG1765@2|Bacteria,1WM1H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_2309572_2	196162.Noca_3308	2.349e-93	313.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DQID@85009|Propionibacteriales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158390_k127_2319274_2	1120950.KB892720_gene1922	7.364e-130	428.0	COG2890@1|root,COG2890@2|Bacteria,2I3KM@201174|Actinobacteria,4DNZ4@85009|Propionibacteriales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
SRR25158390_k127_2319274_6	1449353.JQMQ01000005_gene2680	1.206e-44	172.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria,2NI5K@228398|Streptacidiphilus	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158390_k127_2319274_0	369723.Strop_1560	3.528e-191	606.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DAN2@85008|Micromonosporales	201174|Actinobacteria	G	Beta-glucosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158390_k127_2319274_1	110319.CF8_0661	2.146e-136	447.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DNW0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	pimH	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158390_k127_2319274_7	656024.FsymDg_0257	3.219e-35	141.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4ET3M@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_2319274_5	512565.AMIS_63690	1.026e-85	288.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria,4DDTD@85008|Micromonosporales	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_2319274_4	1313172.YM304_02680	3.702e-101	340.0	COG0258@1|root,COG0258@2|Bacteria,2H2A3@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease, C-terminal SAM fold	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158390_k127_2319274_8	33898.JRHJ01000078_gene982	9.744e-33	128.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2319274_3	33898.JRHJ01000078_gene982	9.166e-106	345.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_2321673_2	1123024.AUII01000007_gene4829	1.081e-128	443.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E1HN@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_2321673_7	743718.Isova_2576	2.037e-90	306.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4F3AY@85017|Promicromonosporaceae	201174|Actinobacteria	V	ABC-2 family transporter protein	drrB	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158390_k127_2321673_5	471852.Tcur_2774	1.205e-99	332.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EFKC@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_2321673_4	1120950.KB892776_gene799	2.897e-102	348.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4DTME@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_2321673_6	1394178.AWOO02000018_gene6649	3.105e-97	331.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHW2@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_2321673_11	1122611.KB903940_gene1994	3.111e-58	205.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4EJX7@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158390_k127_2321673_9	2045.KR76_24765	1.547e-74	259.0	COG1309@1|root,COG1309@2|Bacteria,2HFWX@201174|Actinobacteria,4DUE0@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	mftR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2321673_12	397278.JOJN01000002_gene751	8.341e-35	136.0	COG0535@1|root,COG0535@2|Bacteria,2GQQT@201174|Actinobacteria,4DRIS@85009|Propionibacteriales	201174|Actinobacteria	S	Mycofactocin system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2321673_0	1445613.JALM01000072_gene6615	2.552e-228	711.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria,4DZNS@85010|Pseudonocardiales	201174|Actinobacteria	C	Radical SAM	pqqE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158390_k127_2321673_1	1068978.AMETH_2163	7.08e-192	605.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DXT3@85010|Pseudonocardiales	201174|Actinobacteria	C	Conserved region in glutamate synthase	lldD1	-	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158390_k127_2321673_10	2045.KR76_24785	8.354e-74	277.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4DQ73@85009|Propionibacteriales	201174|Actinobacteria	S	Creatinine amidohydrolase	mftE	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158390_k127_2321673_8	222534.KB893716_gene1808	7.284e-88	300.0	COG1028@1|root,COG1028@2|Bacteria,2ICJK@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_2321673_3	365528.KB891269_gene5980	1.526e-116	394.0	COG1216@1|root,COG1216@2|Bacteria,2I5IC@201174|Actinobacteria,4ESWG@85013|Frankiales	201174|Actinobacteria	S	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_2328924_7	1048339.KB913029_gene4616	3.272e-67	241.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158390_k127_2328924_2	1146883.BLASA_2121	4.491e-117	390.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,4EUSD@85013|Frankiales	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158390_k127_2328924_6	351607.Acel_0973	1.615e-85	287.0	COG2197@1|root,COG2197@2|Bacteria,2IBDE@201174|Actinobacteria,4EUJY@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_2328924_5	351607.Acel_0974	2.576e-87	312.0	COG4585@1|root,COG4585@2|Bacteria,2IAQN@201174|Actinobacteria,4EX42@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA_3
SRR25158390_k127_2328924_9	405948.SACE_1695	5.027e-27	114.0	COG2867@1|root,COG2867@2|Bacteria,2IIBS@201174|Actinobacteria,4E607@85010|Pseudonocardiales	201174|Actinobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2328924_3	1120950.KB892707_gene4826	4.045e-110	367.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4DNXD@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158390_k127_2328924_8	351607.Acel_0980	6.862e-53	194.0	COG3568@1|root,COG3568@2|Bacteria,2GMRU@201174|Actinobacteria	201174|Actinobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_2328924_10	1236902.ANAS01000015_gene570	1.13e-17	90.0	2EN8E@1|root,33FW7@2|Bacteria,2GMI1@201174|Actinobacteria,4EJV7@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2328924_4	1385518.N798_16085	1.271e-97	324.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FEIG@85021|Intrasporangiaceae	201174|Actinobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158390_k127_2328924_0	266940.Krad_3392	6.87e-166	529.0	COG1363@1|root,COG1363@2|Bacteria,2ICG5@201174|Actinobacteria	201174|Actinobacteria	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158390_k127_2328924_1	644283.Micau_0922	1.685e-123	401.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,2GN0U@201174|Actinobacteria,4D9V9@85008|Micromonosporales	201174|Actinobacteria	HJ	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158390_k127_2329478_1	479432.Sros_6890	5.692e-195	633.0	COG5297@1|root,COG5297@2|Bacteria,2GK92@201174|Actinobacteria,4EFJ7@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,Glyco_hydro_6
SRR25158390_k127_2329478_2	749927.AMED_7413	1.826e-140	464.0	COG2730@1|root,COG2755@1|root,COG5297@1|root,COG2730@2|Bacteria,COG2755@2|Bacteria,COG5297@2|Bacteria,2GKTY@201174|Actinobacteria,4DYMC@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_10,CBM_2,Cellulase,Lipase_GDSL_2,fn3
SRR25158390_k127_2329478_0	369723.Strop_2957	0.0	1060.0	COG3188@1|root,COG3188@2|Bacteria,2HQZC@201174|Actinobacteria,4DMG6@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyl hydrolase family 48	cbhB	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_48
SRR25158390_k127_2329478_3	1122138.AQUZ01000091_gene3448	1.665e-61	217.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria,4DQQE@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2329478_5	1121946.AUAX01000027_gene7928	0.0002182	53.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2329478_4	1137269.AZWL01000023_gene1206	8.87e-14	73.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pkn22	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158390_k127_2344368_0	861299.J421_1732	1.72e-132	432.0	COG0308@1|root,COG0308@2|Bacteria,1ZSMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158390_k127_2346386_1	1306174.JODP01000006_gene3563	1.156e-319	983.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158390_k127_2346386_0	1123322.KB904693_gene4559	0.0	1394.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158390_k127_234946_2	590998.Celf_2875	3.214e-06	49.0	COG2334@1|root,COG2334@2|Bacteria,2IJ7M@201174|Actinobacteria,4F1I4@85016|Cellulomonadaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_234946_0	926564.KI911693_gene1035	1.828e-186	588.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4F3FY@85017|Promicromonosporaceae	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR25158390_k127_234946_1	208439.AJAP_32830	5.155e-68	234.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E1PX@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_237183_6	1476876.JOJO01000005_gene5185	6.632e-37	141.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_237183_2	1160718.SU9_04471	1.915e-102	342.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_237183_4	1068978.AMETH_1707	1.816e-59	211.0	COG0645@1|root,COG0645@2|Bacteria,2ISQX@201174|Actinobacteria,4E5VX@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158390_k127_237183_5	1123023.JIAI01000005_gene671	1.319e-46	172.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,4E47X@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158390_k127_237183_1	390989.JOEG01000014_gene3086	1.4e-106	361.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4DD6T@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_237183_0	1120950.KB892757_gene6606	1.757e-139	455.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria,4DNQC@85009|Propionibacteriales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158390_k127_237183_3	644283.Micau_4687	1.837e-101	332.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria,4D8N2@85008|Micromonosporales	201174|Actinobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158390_k127_237183_7	1121272.KB903250_gene2755	1.76e-19	95.0	COG1404@1|root,COG1404@2|Bacteria,2H52A@201174|Actinobacteria,4DJ3R@85008|Micromonosporales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158390_k127_2373032_2	33876.JNXY01000003_gene36	1.703e-26	112.0	COG1846@1|root,COG1846@2|Bacteria,2IM92@201174|Actinobacteria,4DEF1@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158390_k127_2373032_3	485913.Krac_7038	9.377e-19	93.0	2BVHN@1|root,32SWN@2|Bacteria	2|Bacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_2373032_0	269800.Tfu_2332	1.089e-255	800.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4EIEH@85012|Streptosporangiales	201174|Actinobacteria	E	GMC oxidoreductase	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158390_k127_2373032_1	365528.KB891170_gene5165	1.734e-210	659.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4EU1D@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2376074_1	390989.JOEG01000012_gene3462	5.846e-116	379.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158390_k127_2376074_0	1123322.KB904634_gene2305	2.908e-169	535.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158390_k127_2377597_1	644548.SCNU_15724	1.182e-67	241.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4GD4X@85026|Gordoniaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_2377597_2	1194165.CAJF01000031_gene134	8.014e-43	177.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4FN4I@85023|Microbacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_2377597_4	331869.BAL199_05839	3.951e-10	68.0	COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,2UCHN@28211|Alphaproteobacteria,4BST4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_2377597_0	472759.Nhal_0193	3.785e-173	556.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
SRR25158390_k127_2377597_3	670487.Ocepr_1553	8.215e-24	101.0	COG3033@1|root,COG3033@2|Bacteria,1WMCC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Beta-eliminating lyase	-	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158390_k127_239845_13	1120950.KB892759_gene6297	3.263e-26	108.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4DPQG@85009|Propionibacteriales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158390_k127_239845_2	65497.JODV01000003_gene4577	5.52e-131	423.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4DZYK@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158390_k127_239845_4	263358.VAB18032_06520	1.218e-106	356.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DA4V@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_239845_6	103733.JNYO01000004_gene7639	3.797e-84	296.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4DYDP@85010|Pseudonocardiales	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158390_k127_239845_5	590998.Celf_0800	5.228e-98	334.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4F21C@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_239845_11	1120950.KB892751_gene6774	1.369e-37	142.0	2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4DRHQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
SRR25158390_k127_239845_10	1122138.AQUZ01000009_gene4129	3.863e-50	180.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4DR8F@85009|Propionibacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158390_k127_239845_9	1123320.KB889677_gene2744	2.046e-66	231.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158390_k127_239845_0	1179773.BN6_68060	3.527e-268	857.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EF7B@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR25158390_k127_239845_1	67352.JODS01000010_gene4926	6.683e-206	654.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria	201174|Actinobacteria	C	malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158390_k127_239845_8	1206731.BAGB01000171_gene4693	2.318e-72	267.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4FW3P@85025|Nocardiaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	pfkB	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158390_k127_239845_3	526225.Gobs_3643	4.657e-128	419.0	COG0016@1|root,COG0072@1|root,COG0016@2|Bacteria,COG0072@2|Bacteria,2GN8Y@201174|Actinobacteria	201174|Actinobacteria	J	Phenylalanyl-tRNA synthetase	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	FDX-ACB,tRNA-synt_2d
SRR25158390_k127_239845_7	287986.DV20_01740	1.578e-80	278.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4E3VM@85010|Pseudonocardiales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158390_k127_239845_12	67281.JNZZ01000009_gene820	3.914e-31	131.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	MA20_36170	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT,SPOR
SRR25158390_k127_2411454_4	935839.JAGJ01000005_gene2763	3.354e-214	669.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4F3PN@85017|Promicromonosporaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158390_k127_2411454_5	1122138.AQUZ01000001_gene1576	6.643e-194	620.0	COG0166@1|root,COG0166@2|Bacteria,2HZ58@201174|Actinobacteria,4DN42@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GPI family	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158390_k127_2411454_10	935866.JAER01000002_gene1886	3.141e-142	464.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DN6D@85009|Propionibacteriales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158390_k127_2411454_0	479435.Kfla_3272	0.0	1049.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4DN1Y@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158390_k127_2411454_14	105425.BBPL01000001_gene6180	3.754e-101	344.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,2NH46@228398|Streptacidiphilus	201174|Actinobacteria	O	UbiA prenyltransferase family	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158390_k127_2411454_19	103733.JNYO01000044_gene6709	5.981e-70	241.0	COG2258@1|root,COG2258@2|Bacteria,2GMBE@201174|Actinobacteria,4E2KE@85010|Pseudonocardiales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158390_k127_2411454_2	2002.JOEQ01000002_gene4476	5.983e-232	733.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4EGGJ@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158390_k127_2411454_3	1463841.JOIR01000011_gene2805	3.104e-220	690.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_2411454_20	2074.JNYD01000006_gene1625	1.448e-65	231.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_2411454_27	263358.VAB18032_08180	8.676e-46	167.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria,4DDMQ@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_2411454_24	436229.JOEH01000007_gene4007	9.997e-56	199.0	2E4HJ@1|root,32ZCP@2|Bacteria,2IIYC@201174|Actinobacteria,2NN4A@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2411454_30	1463820.JOGW01000015_gene2379	7.555e-11	72.0	2ED20@1|root,336YY@2|Bacteria,2IAKX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2411454_29	1120950.KB892773_gene1076	2.526e-39	155.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DSC5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2411454_25	1157637.KB892113_gene4805	9.962e-55	198.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2411454_23	1155718.KB891885_gene6450	6.938e-62	214.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
SRR25158390_k127_2411454_7	479432.Sros_4650	7.898e-180	570.0	COG0477@1|root,COG2814@2|Bacteria,2GK22@201174|Actinobacteria,4EGZS@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2411454_9	479432.Sros_4649	2.809e-143	458.0	COG0583@1|root,COG0583@2|Bacteria,2GNAH@201174|Actinobacteria,4EKNY@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_2411454_8	1206737.BAGF01000081_gene5196	3.057e-161	516.0	COG1073@1|root,COG1073@2|Bacteria,2H20M@201174|Actinobacteria,4G9PP@85025|Nocardiaceae	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158390_k127_2411454_21	1120949.KB903294_gene4183	1.203e-64	228.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4DCZI@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2411454_18	1120950.KB892707_gene4644	2.422e-80	279.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4DQ6X@85009|Propionibacteriales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158390_k127_2411454_16	235985.BBPN01000001_gene1043	1.535e-87	297.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NEI5@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158390_k127_2411454_13	67257.JODR01000012_gene6090	5.648e-114	376.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2411454_15	479435.Kfla_3277	2.954e-90	304.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4DQCB@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR25158390_k127_2411454_1	1123322.KB904653_gene778	8.72e-279	860.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria	201174|Actinobacteria	O	assembly protein sufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158390_k127_2411454_12	1298863.AUEP01000005_gene2433	4.078e-131	437.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4DPCK@85009|Propionibacteriales	201174|Actinobacteria	O	Uncharacterized protein family (UPF0051)	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158390_k127_2411454_28	1120950.KB892707_gene4652	7.33e-41	167.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4DRMD@85009|Propionibacteriales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158390_k127_2411454_11	1089455.MOPEL_096_00900	5.068e-132	424.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4F6M7@85018|Dermatophilaceae	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158390_k127_2411454_6	1869.MB27_00215	6.057e-186	589.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4D8WS@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158390_k127_2411454_22	1445613.JALM01000094_gene3845	6.9e-63	224.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4E2WE@85010|Pseudonocardiales	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158390_k127_2411454_26	1048339.KB913029_gene4333	7.5e-52	188.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4ESWH@85013|Frankiales	201174|Actinobacteria	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158390_k127_2411454_17	1120950.KB892708_gene4335	9.401e-86	290.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4DQIB@85009|Propionibacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158390_k127_2420835_9	644283.Micau_3864	2.47e-70	254.0	2DBGS@1|root,2Z95N@2|Bacteria,2ICPX@201174|Actinobacteria,4DAIQ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2420835_13	1120950.KB892779_gene939	5.028e-49	180.0	COG0838@1|root,COG0838@2|Bacteria,2IFDT@201174|Actinobacteria,4DVBJ@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	nuoA2	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158390_k127_2420835_7	1996.JOFO01000106_gene798	4.196e-94	319.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria,4EHDU@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158390_k127_2420835_11	1463934.JOCF01000001_gene6951	3.193e-65	228.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158390_k127_2420835_2	1120950.KB892779_gene936	6.246e-146	467.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria,4DU89@85009|Propionibacteriales	201174|Actinobacteria	C	NADH dehydrogenase	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158390_k127_2420835_8	1169154.KB897780_gene2420	1.438e-82	279.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158390_k127_2420835_14	1120950.KB892779_gene934	1.281e-37	149.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria,4DV5E@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158390_k127_2420835_15	1449347.JQLN01000005_gene5323	7.913e-36	140.0	COG0713@1|root,COG0713@2|Bacteria,2IHNW@201174|Actinobacteria,2M386@2063|Kitasatospora	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158390_k127_2420835_16	1120950.KB892779_gene932	2.148e-33	134.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DT5U@85009|Propionibacteriales	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158390_k127_2420835_6	1120950.KB892779_gene932	9.949e-115	385.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DT5U@85009|Propionibacteriales	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158390_k127_2420835_0	1120950.KB892779_gene931	5.388e-189	605.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4DN4B@85009|Propionibacteriales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_2420835_5	43759.JNWK01000006_gene574	1.931e-126	422.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158390_k127_2420835_10	512565.AMIS_56890	4.038e-68	260.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4DEXE@85008|Micromonosporales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158390_k127_2420835_4	711393.AYRX01000065_gene2273	2.442e-127	414.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_2420835_3	105422.BBPM01000001_gene4917	2.514e-128	429.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,2NGZ5@228398|Streptacidiphilus	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158390_k127_2420835_1	479433.Caci_4902	4.379e-175	562.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2420835_12	68170.KL590487_gene8722	1.207e-51	191.0	COG2030@1|root,COG2030@2|Bacteria,2GIXP@201174|Actinobacteria,4E334@85010|Pseudonocardiales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_2420835_17	882083.SacmaDRAFT_2715	1.666e-27	126.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,4EA33@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158390_k127_2425650_23	1121939.L861_14945	5.739e-54	197.0	COG2197@1|root,COG2197@2|Bacteria,1R03J@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_2425650_15	644283.Micau_1531	3.398e-101	345.0	COG0477@1|root,COG0477@2|Bacteria,2IIAH@201174|Actinobacteria,4D9T1@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158390_k127_2425650_16	644283.Micau_4067	2.713e-84	293.0	COG0500@1|root,COG0500@2|Bacteria,2I63A@201174|Actinobacteria,4DH7S@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25
SRR25158390_k127_2425650_6	1194165.CAJF01000042_gene1657	5.225e-153	490.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4FMT9@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_2425650_1	1043493.BBLU01000009_gene579	1.675e-217	685.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158390_k127_2425650_5	1194165.CAJF01000042_gene1659	6.629e-155	496.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4FNEX@85023|Microbacteriaceae	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057,ko:K10440,ko:K17209	ko02010,map02010	M00212,M00221,M00592	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21	-	-	BPD_transp_2
SRR25158390_k127_2425650_8	979556.MTES_2138	2.894e-149	481.0	COG1172@1|root,COG1172@2|Bacteria,2HB45@201174|Actinobacteria,4FKVA@85023|Microbacteriaceae	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	ytfT	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158390_k127_2425650_0	1043493.BBLU01000009_gene582	4.439e-234	734.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158390_k127_2425650_7	1194165.CAJF01000042_gene1662	1.941e-152	488.0	COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria,4FMVP@85023|Microbacteriaceae	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158390_k127_2425650_11	247156.NFA_47860	3.696e-107	354.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria,4FWTM@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_2425650_21	247156.NFA_47870	2.039e-62	218.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4G2AF@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2425650_3	44060.JODL01000011_gene1970	2.055e-183	599.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158390_k127_2425650_27	1449976.KALB_238	2.836e-28	118.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4E4G9@85010|Pseudonocardiales	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158390_k127_2425650_10	953739.SVEN_3374	4.136e-111	362.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158390_k127_2425650_20	33898.JRHJ01000001_gene644	2.306e-63	222.0	299JI@1|root,2ZWN1@2|Bacteria,2GMZP@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF5063)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
SRR25158390_k127_2425650_18	1123258.AQXZ01000011_gene1614	5.913e-69	257.0	COG1277@1|root,COG1277@2|Bacteria,2IIXQ@201174|Actinobacteria,4G39I@85025|Nocardiaceae	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158390_k127_2425650_14	1123258.AQXZ01000011_gene1621	1.237e-102	344.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria,4G1CT@85025|Nocardiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2425650_2	469371.Tbis_3528	2.272e-206	649.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4DYQ8@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158390_k127_2425650_4	471852.Tcur_4887	4.221e-179	566.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4EGS7@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158390_k127_2425650_28	1095767.CAHD01000046_gene1426	2.026e-15	87.0	2DPU0@1|root,333DA@2|Bacteria,2ISQC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2425650_24	298653.Franean1_6166	1.871e-52	188.0	COG2044@1|root,COG2044@2|Bacteria,2IHT6@201174|Actinobacteria,4EVHU@85013|Frankiales	201174|Actinobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158390_k127_2425650_19	1123320.KB889669_gene3193	5.637e-68	235.0	COG4044@1|root,COG4044@2|Bacteria,2GKGF@201174|Actinobacteria	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR25158390_k127_2425650_25	1122611.KB903970_gene2598	2.684e-52	188.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4EJ9C@85012|Streptosporangiales	201174|Actinobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158390_k127_2425650_9	1123320.KB889669_gene3191	7.865e-126	411.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158390_k127_2425650_22	1150599.MPHLEI_26347	4.466e-57	207.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,239CY@1762|Mycobacteriaceae	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158390_k127_2425650_13	1122609.AUGT01000009_gene3164	2.984e-103	347.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4DNR5@85009|Propionibacteriales	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158390_k127_2425650_26	1120950.KB892745_gene2909	6.798e-33	132.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,4DS23@85009|Propionibacteriales	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2425650_17	443218.AS9A_3074	3.126e-69	249.0	COG5340@1|root,COG5340@2|Bacteria,2H6VP@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_2425650_12	66377.JOBH01000006_gene181	1.594e-103	348.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
SRR25158390_k127_2425682_7	1121946.AUAX01000021_gene8055	1.651e-95	329.0	COG4993@1|root,COG4993@2|Bacteria,2I3R4@201174|Actinobacteria,4DFND@85008|Micromonosporales	201174|Actinobacteria	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
SRR25158390_k127_2425682_11	65497.JODV01000007_gene660	2.462e-77	271.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4E3VW@85010|Pseudonocardiales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158390_k127_2425682_16	749927.AMED_5765	2.139e-18	87.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria,4E0HY@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158390_k127_2425682_4	66377.JOBH01000006_gene268	3.315e-151	483.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158390_k127_2425682_14	500153.JOEK01000008_gene2423	1.391e-33	131.0	COG0490@1|root,COG0490@2|Bacteria,2IQQA@201174|Actinobacteria	201174|Actinobacteria	P	domain, Protein	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_2425682_15	1172179.AUKV01000010_gene4055	3.115e-27	119.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158390_k127_2425682_3	500153.JOEK01000008_gene2424	6.766e-156	498.0	COG0475@1|root,COG5207@1|root,COG0475@2|Bacteria,COG5207@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
SRR25158390_k127_2425682_17	1463879.JOHP01000006_gene6271	6.95e-05	46.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR25158390_k127_2425682_8	1120949.KB903301_gene6342	6.566e-94	327.0	COG1414@1|root,COG1414@2|Bacteria,2IHHB@201174|Actinobacteria,4DI1B@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_2425682_6	1394178.AWOO02000050_gene6188	2.369e-104	345.0	COG0372@1|root,COG0372@2|Bacteria,2H9YP@201174|Actinobacteria,4EMJE@85012|Streptosporangiales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_2425682_2	1394178.AWOO02000050_gene6187	7.588e-163	521.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4EN53@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158390_k127_2425682_1	1869.MB27_24560	9.829e-193	612.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158390_k127_2425682_10	1343740.M271_18760	3.206e-87	293.0	COG1309@1|root,COG1309@2|Bacteria,2H47F@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158390_k127_2425682_9	1380347.JNII01000005_gene3373	5.799e-91	308.0	COG0169@1|root,COG0169@2|Bacteria,2GPXV@201174|Actinobacteria,4EUPY@85013|Frankiales	201174|Actinobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0030266,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Sacchrp_dh_NADP,Shikimate_DH,Shikimate_dh_N,ThiF
SRR25158390_k127_2425682_0	1120949.KB903330_gene9161	3.708e-262	820.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DHQS@85008|Micromonosporales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_2425682_5	1137271.AZUM01000008_gene2031	1.899e-116	387.0	COG1638@1|root,COG1638@2|Bacteria,2HTG5@201174|Actinobacteria,4E68R@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP
SRR25158390_k127_2425682_12	1101188.KI912155_gene3247	1.416e-42	165.0	COG1028@1|root,COG1028@2|Bacteria	1101188.KI912155_gene3247|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2425682_13	1137271.AZUM01000008_gene2029	1.142e-36	145.0	COG3090@1|root,COG3090@2|Bacteria,2GR08@201174|Actinobacteria	201174|Actinobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
SRR25158390_k127_243924_0	35754.JNYJ01000064_gene1412	1.253e-172	589.0	COG1112@1|root,COG1198@1|root,COG1112@2|Bacteria,COG1198@2|Bacteria,2GKJW@201174|Actinobacteria,4DBGN@85008|Micromonosporales	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
SRR25158390_k127_2449213_0	1150398.JIBJ01000004_gene2813	3.798e-274	866.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158390_k127_2449213_5	471857.Svir_34190	5.975e-115	398.0	COG0314@1|root,COG0521@1|root,COG0314@2|Bacteria,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4DZNU@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
SRR25158390_k127_2449213_13	1223543.GP2_033_00630	1.25e-27	119.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4GET7@85026|Gordoniaceae	201174|Actinobacteria	K	Ribonuclease B OB domain	cspA_1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158390_k127_2449213_3	357808.RoseRS_0796	2.527e-122	401.0	COG3458@1|root,COG3458@2|Bacteria,2G5R9@200795|Chloroflexi,376UE@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Acetyl xylan esterase	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
SRR25158390_k127_2449213_6	1313172.YM304_24240	8.521e-107	366.0	COG2304@1|root,COG2304@2|Bacteria,2GKDC@201174|Actinobacteria	201174|Actinobacteria	O	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158390_k127_2449213_10	1123024.AUII01000057_gene4361	1.133e-55	197.0	COG1742@1|root,COG1742@2|Bacteria,2IKM8@201174|Actinobacteria,4E4I4@85010|Pseudonocardiales	201174|Actinobacteria	S	UPF0060 membrane protein	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
SRR25158390_k127_2449213_1	479434.Sthe_1229	2.108e-130	434.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_2449213_8	164757.Mjls_0415	9.77e-82	280.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_2449213_12	33876.JNXY01000014_gene3958	2.556e-29	121.0	2E6IT@1|root,3315W@2|Bacteria,2GR2R@201174|Actinobacteria,4DFKV@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR25158390_k127_2449213_2	263358.VAB18032_19900	2.613e-128	416.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4D8TS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158390_k127_2449213_9	390989.JOEG01000001_gene5122	1.5e-73	252.0	COG3358@1|root,COG3358@2|Bacteria,2GP66@201174|Actinobacteria,4DMBB@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158390_k127_2449213_4	312284.A20C1_12395	1.16e-120	394.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,3UX14@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Aldo/keto reductase family	dkgA	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158390_k127_2449213_14	1169161.KB897722_gene4469	1.641e-22	101.0	COG1378@1|root,COG2197@1|root,COG1378@2|Bacteria,COG2197@2|Bacteria,2GN8F@201174|Actinobacteria	201174|Actinobacteria	K	bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TrmB
SRR25158390_k127_2449213_7	1122138.AQUZ01000022_gene8719	2.314e-101	339.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DUT2@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_2449213_11	1150864.MILUP08_41972	1.808e-50	181.0	COG3795@1|root,COG3795@2|Bacteria,2HQVU@201174|Actinobacteria,4DFG1@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_245294_3	1229203.KI301992_gene424	5.376e-58	203.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,3UWRC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	HP	ThiF family	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158390_k127_245294_2	469371.Tbis_3323	1.945e-130	447.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4E4A4@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158390_k127_245294_4	590998.Celf_1414	8.366e-31	124.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,4F1I1@85016|Cellulomonadaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR25158390_k127_245294_0	1120950.KB892749_gene3377	0.0	1214.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4DPY8@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158390_k127_245294_1	1120950.KB892749_gene3376	5.121e-282	897.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4DP1P@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158390_k127_2465796_6	1121272.KB903250_gene3238	0.0001668	44.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4D9TG@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
SRR25158390_k127_2465796_3	211114.JOEF01000002_gene4098	1.719e-37	143.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4E4CI@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Helix-turn-helix	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158390_k127_2465796_5	1169161.KB897713_gene6659	3.584e-11	70.0	28UHU@1|root,2ZGNH@2|Bacteria,2I8HA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K16645	-	-	-	-	ko00000,ko00536	-	-	-	-
SRR25158390_k127_2465796_4	266940.Krad_0886	2.075e-22	102.0	2EHMU@1|root,33BDI@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
SRR25158390_k127_2465796_0	644283.Micau_5698	2.066e-108	355.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria,4DAMA@85008|Micromonosporales	201174|Actinobacteria	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR25158390_k127_2465796_1	1032480.MLP_02100	4.115e-86	299.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DP9F@85009|Propionibacteriales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158390_k127_2465796_2	469371.Tbis_2327	1.118e-44	169.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4E2Z5@85010|Pseudonocardiales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158390_k127_2466024_2	1177594.MIC448_2040025	3.271e-57	202.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FMND@85023|Microbacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158390_k127_2466024_1	1177594.MIC448_2040027	6.37e-107	362.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158390_k127_2466024_0	1177594.MIC448_2040009	1.189e-209	659.0	COG1249@1|root,COG1249@2|Bacteria,2I3I8@201174|Actinobacteria	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
SRR25158390_k127_2466024_3	1177594.MIC448_2040008	3.384e-35	138.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4FK4F@85023|Microbacteriaceae	201174|Actinobacteria	EG	dihydroxy-acid dehydratase activity	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158390_k127_2469803_0	479432.Sros_8727	3.046e-141	456.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4EMDK@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_2469803_4	479432.Sros_8728	1.478e-59	218.0	COG2128@1|root,COG2128@2|Bacteria,2HSVU@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_2469803_2	469383.Cwoe_0514	1.102e-75	259.0	28SI0@1|root,2ZEUB@2|Bacteria,2GNT0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158390_k127_2469803_5	287986.DV20_05545	3.291e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,2HNDG@201174|Actinobacteria,4E6E8@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2469803_6	1246995.AFR_15400	7.141e-53	188.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DK6U@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2469803_1	356851.JOAN01000018_gene5632	3.583e-92	311.0	COG0631@1|root,COG0631@2|Bacteria,2GMVJ@201174|Actinobacteria,4DIN0@85008|Micromonosporales	201174|Actinobacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
SRR25158390_k127_2469803_3	405948.SACE_6985	1.477e-62	218.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria,4E2W4@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2473240_6	1122609.AUGT01000004_gene1309	8.296e-28	120.0	COG0776@1|root,COG1754@1|root,COG0776@2|Bacteria,COG1754@2|Bacteria,2GV0M@201174|Actinobacteria,4DR53@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the bacterial histone-like protein family	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158390_k127_2473240_1	570268.ANBB01000012_gene5493	1.307e-149	487.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4EI2C@85012|Streptosporangiales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_2473240_3	1435356.Y013_02205	6.34e-114	377.0	COG1253@1|root,COG1253@2|Bacteria,2GJ8X@201174|Actinobacteria,4FW9E@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
SRR25158390_k127_2473240_4	1151118.KB895783_gene3365	5.644e-98	325.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,1W7HE@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158390_k127_2473240_0	928724.SacglDRAFT_00983	2.313e-260	810.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4DZ56@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158390_k127_2473240_2	1120950.KB892741_gene2690	2.566e-115	380.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4DP77@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_2473240_5	935839.JAGJ01000002_gene707	2.362e-36	140.0	2EDGM@1|root,32W2W@2|Bacteria,2I8A9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2477969_9	446468.Ndas_2919	1.568e-64	224.0	COG0300@1|root,COG0300@2|Bacteria,2GK2K@201174|Actinobacteria,4EME6@85012|Streptosporangiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2477969_13	1122138.AQUZ01000075_gene7356	2.6e-37	152.0	COG2852@1|root,COG2852@2|Bacteria,2IGEW@201174|Actinobacteria,4DUUG@85009|Propionibacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158390_k127_2477969_0	665577.JH993790_gene5741	2.156e-192	614.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_2477969_3	298654.FraEuI1c_5723	5.286e-137	448.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4ERQ1@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158390_k127_2477969_14	1123322.KB904650_gene1872	0.0004289	50.0	2APTH@1|root,31EXS@2|Bacteria,2ICVP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2477969_6	105422.BBPM01000030_gene3759	8.334e-76	268.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,2NERP@228398|Streptacidiphilus	201174|Actinobacteria	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158390_k127_2477969_4	1394178.AWOO02000078_gene2040	5.273e-120	396.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4EIC2@85012|Streptosporangiales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158390_k127_2477969_2	471852.Tcur_3871	6.278e-171	544.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4EHYN@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158390_k127_2477969_12	469371.Tbis_0937	1.149e-37	144.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4E5BP@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM MoaD family protein	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_2477969_7	479432.Sros_1725	2.476e-65	227.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4EJ5N@85012|Streptosporangiales	201174|Actinobacteria	S	JAB/MPN domain	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158390_k127_2477969_11	397278.JOJN01000007_gene3127	5.785e-46	172.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4DQGY@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158390_k127_2477969_10	1120950.KB892709_gene4055	8.727e-47	169.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4DRQZ@85009|Propionibacteriales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158390_k127_2477969_1	1386089.N865_12155	2.192e-181	576.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4FFB9@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158390_k127_2477969_5	1120950.KB892709_gene4053	6.022e-87	291.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4DQD6@85009|Propionibacteriales	201174|Actinobacteria	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158390_k127_2477969_8	1120950.KB892760_gene5720	3.673e-65	228.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria,4DREX@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2479633_8	1068978.AMETH_1486	3.709e-43	170.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria,4E3GV@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_2479633_10	1384049.CD29_15920	1.548e-13	81.0	COG0454@1|root,COG0456@2|Bacteria,1V6GD@1239|Firmicutes,4HJ94@91061|Bacilli,3IXXZ@400634|Lysinibacillus	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158390_k127_2479633_5	1380356.JNIK01000013_gene4119	3.721e-58	207.0	COG4977@1|root,COG4977@2|Bacteria,2I3BT@201174|Actinobacteria,4EVE0@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_2479633_6	1463917.JODC01000007_gene7537	2.6e-55	203.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2479633_7	1121406.JAEX01000003_gene1560	2.636e-49	196.0	COG0477@1|root,COG2814@2|Bacteria,1PG3D@1224|Proteobacteria,42S62@68525|delta/epsilon subdivisions,2WNYR@28221|Deltaproteobacteria,2MGPZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158390_k127_2479633_2	526225.Gobs_4207	1.103e-100	334.0	COG0656@1|root,COG0656@2|Bacteria,2HGQC@201174|Actinobacteria	201174|Actinobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_2479633_4	749414.SBI_07094	3.383e-66	237.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158390_k127_2479633_3	935839.JAGJ01000027_gene2810	1.536e-85	288.0	COG3917@1|root,COG3917@2|Bacteria,2I2EX@201174|Actinobacteria,4F4BI@85017|Promicromonosporaceae	201174|Actinobacteria	Q	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158390_k127_2479633_0	1137268.AZXF01000027_gene2564	8.334e-313	983.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4EHVC@85012|Streptosporangiales	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158390_k127_2479633_1	471853.Bcav_3669	2.241e-185	590.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiB	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158390_k127_2479633_9	1121272.KB903249_gene1442	1.497e-31	127.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,4DEV6@85008|Micromonosporales	201174|Actinobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158390_k127_2489163_0	1177594.MIC448_2040008	2.317e-192	609.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4FK4F@85023|Microbacteriaceae	201174|Actinobacteria	EG	dihydroxy-acid dehydratase activity	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158390_k127_2489163_5	882083.SacmaDRAFT_2659	5.522e-43	169.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_2489163_1	67356.KL575594_gene4697	1.104e-187	602.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2489163_3	106370.Francci3_2514	4.034e-122	401.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4ETVY@85013|Frankiales	201174|Actinobacteria	S	Zinc-binding dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_2489163_4	1227499.C493_02211	2.101e-50	190.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea,2Y385@28890|Euryarchaeota,23ZCI@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_2489163_2	710687.KI912270_gene1294	2.107e-130	450.0	COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRR25158390_k127_2552962_2	685727.REQ_40330	2.091e-78	276.0	COG2367@1|root,COG2367@2|Bacteria,2HUYP@201174|Actinobacteria,4FWQC@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158390_k127_2552962_4	1184609.KILIM_004_01090	3.472e-47	181.0	COG0583@1|root,COG0583@2|Bacteria,2I93E@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_2552962_1	110319.CF8_3587	7.183e-191	619.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4DP57@85009|Propionibacteriales	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	pbp2B	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158390_k127_2552962_5	1380356.JNIK01000005_gene969	8.81e-38	153.0	290SX@1|root,2ZNF0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2552962_0	28042.GU90_10290	0.0	1189.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4DXMY@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
SRR25158390_k127_2552962_3	1463864.JOGO01000044_gene803	3.149e-53	189.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158390_k127_2590430_11	408672.NBCG_00751	1.296e-18	87.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158390_k127_2590430_9	1089544.KB912942_gene490	1.884e-33	132.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_2590430_5	1157634.KB912943_gene4047	3.246e-50	187.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158390_k127_2590430_2	1120950.KB892708_gene4496	3.617e-151	484.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4DNQ8@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158390_k127_2590430_1	1125971.ASJB01000031_gene1284	5.638e-161	511.0	COG1830@1|root,COG1830@2|Bacteria,2HPYY@201174|Actinobacteria,4E70X@85010|Pseudonocardiales	201174|Actinobacteria	G	Aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158390_k127_2590430_3	471852.Tcur_0500	9.517e-104	343.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_2590430_7	1179773.BN6_56290	1.843e-36	151.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_2590430_8	101510.RHA1_ro00061	6.942e-36	147.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4FWRF@85025|Nocardiaceae	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_2590430_0	2002.JOEQ01000013_gene5466	3.045e-190	609.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4EGQJ@85012|Streptosporangiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
SRR25158390_k127_2590430_6	479432.Sros_4105	5.643e-44	163.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJNW@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158390_k127_2590430_4	1944.JOAZ01000018_gene3895	1.799e-63	224.0	COG1309@1|root,COG1309@2|Bacteria,2IJ0U@201174|Actinobacteria,4192F@629295|Streptomyces griseus group	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_2590430_10	1246448.ANAZ01000015_gene6064	2.473e-25	107.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4ENTU@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_2618925_3	471852.Tcur_3615	3.847e-175	558.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4EGP1@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158390_k127_2618925_2	1137271.AZUM01000008_gene2051	8.053e-177	565.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4DXKJ@85010|Pseudonocardiales	201174|Actinobacteria	F	Formiminoglutamate deiminase	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_2618925_7	469371.Tbis_2843	1.197e-57	213.0	29QD5@1|root,30BCD@2|Bacteria,2IG1I@201174|Actinobacteria,4E2MQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
SRR25158390_k127_2618925_5	1128421.JAGA01000002_gene335	3.295e-117	392.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_2618925_4	1123023.JIAI01000002_gene4963	2.542e-149	504.0	COG0624@1|root,COG0624@2|Bacteria,2GJDE@201174|Actinobacteria,4DXJV@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase family M28	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_2618925_6	263358.VAB18032_19305	2.84e-109	370.0	COG0477@1|root,COG0477@2|Bacteria,2I2Q2@201174|Actinobacteria	201174|Actinobacteria	EGP	Drug resistance transporter, bcr cfla subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRR25158390_k127_2618925_0	1122611.KB903996_gene7477	4.865e-309	952.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4EFM1@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158390_k127_2618925_1	1449355.JQNR01000005_gene2488	1.274e-181	573.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria	201174|Actinobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158390_k127_2620590_9	1089545.KB913037_gene2271	2.429e-63	222.0	COG3327@1|root,COG3327@2|Bacteria,2IDVQ@201174|Actinobacteria,4E8NN@85010|Pseudonocardiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158390_k127_2620590_2	1125971.ASJB01000065_gene6243	5.086e-166	540.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4E19E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_2620590_12	2045.KR76_08310	7.241e-48	183.0	2FJ4K@1|root,34AUV@2|Bacteria,2GVYD@201174|Actinobacteria,4DS69@85009|Propionibacteriales	201174|Actinobacteria	S	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
SRR25158390_k127_2620590_10	935866.JAER01000022_gene2904	7.439e-61	224.0	COG2378@1|root,COG2378@2|Bacteria,2IMC4@201174|Actinobacteria,4DRG9@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158390_k127_2620590_0	471852.Tcur_1235	2.565e-263	832.0	COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria,4EHCF@85012|Streptosporangiales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	cpdB	-	3.1.3.5,3.1.3.6,3.1.4.16	ko:K01081,ko:K01119	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158390_k127_2620590_6	1416759.AYMR01000008_gene2626	1.341e-106	356.0	COG3525@1|root,COG4733@1|root,COG3525@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	celN	-	3.2.1.35,3.2.1.52,3.2.1.78	ko:K01197,ko:K01218,ko:K12373	ko00051,ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko02024,ko04142,map00051,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map02024,map04142	M00076,M00077,M00079	R00022,R01332,R06004,R07824,R07825,R10905,R11316	RC00049,RC00467	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko03110	-	GH20,GH26	-	Esterase_phd,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Lipase_GDSL_2,NAGidase,RicinB_lectin_2,fn3
SRR25158390_k127_2620590_13	110319.CF8_1918	1.105e-12	77.0	COG3764@1|root,COG3764@2|Bacteria,2IRXZ@201174|Actinobacteria,4DRSR@85009|Propionibacteriales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158390_k127_2620590_7	365528.KB891220_gene1174	1.432e-80	287.0	COG1215@1|root,COG1215@2|Bacteria,2I5R7@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
SRR25158390_k127_2620590_5	365528.KB891220_gene1172	1.324e-128	422.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4ESVX@85013|Frankiales	201174|Actinobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158390_k127_2620590_8	649831.L083_4084	2.165e-75	263.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4DA6A@85008|Micromonosporales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_2620590_1	1048339.KB913029_gene3508	8.328e-222	713.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4ERG2@85013|Frankiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158390_k127_2620590_11	561175.KB894094_gene1860	3.831e-53	190.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4EJDG@85012|Streptosporangiales	201174|Actinobacteria	E	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158390_k127_2620590_3	471852.Tcur_3427	7.27e-153	494.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4EGPB@85012|Streptosporangiales	201174|Actinobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158390_k127_2620590_4	1288083.AUKR01000002_gene4383	2.722e-147	475.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158390_k127_2621287_3	471857.Svir_18080	4.546e-42	160.0	COG0640@1|root,COG0640@2|Bacteria,2IEHG@201174|Actinobacteria,4E40T@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_2621287_0	471857.Svir_18070	3.505e-119	392.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria,4E5K0@85010|Pseudonocardiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
SRR25158390_k127_2621287_1	1246995.AFR_36830	5.496e-80	274.0	COG0842@1|root,COG0842@2|Bacteria,2IITR@201174|Actinobacteria	201174|Actinobacteria	V	Abc-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2621287_2	882083.SacmaDRAFT_2957	2.519e-73	249.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXK7@85010|Pseudonocardiales	201174|Actinobacteria	P	E1-E2 ATPase	copB	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158390_k127_2625137_0	68260.JOAY01000018_gene3346	4.468e-197	622.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158390_k127_2625137_1	269800.Tfu_1647	2.886e-192	606.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EHDP@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	acdA3	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2625137_2	443218.AS9A_3074	2.372e-62	221.0	COG5340@1|root,COG5340@2|Bacteria,2H6VP@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_2625883_18	28444.JODQ01000003_gene4715	2.312e-96	321.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158390_k127_2625883_17	397278.JOJN01000004_gene1423	2.336e-105	350.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DN3T@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158390_k127_2625883_22	1120950.KB892708_gene4360	9.268e-85	287.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4DNJB@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_2625883_11	1120950.KB892708_gene4359	4.812e-135	441.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4DN0Q@85009|Propionibacteriales	201174|Actinobacteria	O	prohibitin homologues	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158390_k127_2625883_34	1120950.KB892708_gene4358	4.707e-37	144.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,4DRK6@85009|Propionibacteriales	201174|Actinobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158390_k127_2625883_15	1032480.MLP_14790	3.984e-111	366.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DNDT@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158390_k127_2625883_38	743718.Isova_1388	5.027e-32	135.0	2DN6F@1|root,32VT2@2|Bacteria,2I0K5@201174|Actinobacteria,4F49U@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2625883_10	471852.Tcur_4820	8.211e-151	487.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4EFXE@85012|Streptosporangiales	201174|Actinobacteria	E	ACT domain	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
SRR25158390_k127_2625883_35	1476876.JOJO01000033_gene3905	1.479e-36	146.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria	201174|Actinobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158390_k127_2625883_14	196162.Noca_2572	3.554e-117	390.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4DNM7@85009|Propionibacteriales	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_2625883_16	105420.BBPO01000035_gene471	3.866e-108	357.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,2NG0C@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_2625883_39	1449355.JQNR01000005_gene2478	2.9e-29	117.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158390_k127_2625883_42	1386089.N865_08035	4.485e-13	81.0	2EGIC@1|root,33AAH@2|Bacteria,2GQ88@201174|Actinobacteria,4FHIH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3099)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3099
SRR25158390_k127_2625883_29	1120950.KB892707_gene4686	1.827e-47	180.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4DR52@85009|Propionibacteriales	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158390_k127_2625883_40	1214101.BN159_6686	1.79e-25	106.0	2E4I7@1|root,32ZDA@2|Bacteria,2IQBB@201174|Actinobacteria	201174|Actinobacteria	S	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2625883_1	1123322.KB904678_gene3158	8.362e-255	795.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158390_k127_2625883_33	1713.JOFV01000005_gene2372	4.519e-38	152.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4F1HJ@85016|Cellulomonadaceae	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158390_k127_2625883_21	1713.JOFV01000005_gene2369	1.664e-88	298.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4F15F@85016|Cellulomonadaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
SRR25158390_k127_2625883_31	1713.JOFV01000005_gene2368	2.133e-41	162.0	COG0619@1|root,COG0619@2|Bacteria,2IQMQ@201174|Actinobacteria,4F1JB@85016|Cellulomonadaceae	201174|Actinobacteria	P	Cobalt transport protein	bioN	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
SRR25158390_k127_2625883_37	2002.JOEQ01000006_gene1362	2.365e-34	136.0	COG1848@1|root,COG1848@2|Bacteria,2GVQ7@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_2625883_2	471852.Tcur_3003	1.285e-229	731.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4EHCM@85012|Streptosporangiales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158390_k127_2625883_6	1957.JODX01000010_gene621	7.563e-177	562.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158390_k127_2625883_32	935866.JAER01000002_gene1998	2.654e-38	149.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4DRNP@85009|Propionibacteriales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158390_k127_2625883_24	2045.KR76_14630	1.878e-69	244.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4DQBB@85009|Propionibacteriales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158390_k127_2625883_30	253839.SSNG_01327	1.189e-42	158.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2625883_20	1137269.AZWL01000002_gene6470	2.488e-94	319.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158390_k127_2625883_12	570268.ANBB01000054_gene4630	1.987e-120	397.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4EHA4@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158390_k127_2625883_0	1120950.KB892708_gene4316	0.0	1733.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4DNSQ@85009|Propionibacteriales	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158390_k127_2625883_5	2045.KR76_14665	1.484e-183	580.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4DNY4@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158390_k127_2625883_3	397278.JOJN01000017_gene2551	9.873e-206	664.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4DMZJ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158390_k127_2625883_9	1449355.JQNR01000005_gene5272	1.138e-153	492.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158390_k127_2625883_23	469371.Tbis_1351	3.289e-76	259.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4DZ0J@85010|Pseudonocardiales	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158390_k127_2625883_8	570268.ANBB01000044_gene1858	3.298e-156	499.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria,4EHET@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158390_k127_2625883_28	1133849.O3I_041825	1.553e-49	184.0	COG4758@1|root,COG4758@2|Bacteria,2GXVR@201174|Actinobacteria,4G1SS@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_2625883_27	479435.Kfla_4348	4.01e-52	187.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4DR4N@85009|Propionibacteriales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158390_k127_2625883_19	1048339.KB913029_gene3969	3.096e-96	318.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4ERK9@85013|Frankiales	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158390_k127_2625883_13	1123320.KB889665_gene1418	1.511e-118	393.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_2625883_41	235985.BBPN01000023_gene2607	1.173e-24	113.0	COG0454@1|root,COG0456@2|Bacteria,2GZDT@201174|Actinobacteria,2NIFT@228398|Streptacidiphilus	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_2625883_25	351607.Acel_1306	3.447e-63	226.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4ESSK@85013|Frankiales	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158390_k127_2625883_7	1449353.JQMQ01000005_gene854	2.521e-161	516.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,2NHGC@228398|Streptacidiphilus	201174|Actinobacteria	E	3-dehydroquinate synthase	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158390_k127_2625883_26	471853.Bcav_2020	4.131e-60	212.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158390_k127_2625883_4	1134445.AJJM01000025_gene4365	7.514e-194	612.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158390_k127_2625883_36	1120950.KB892708_gene4301	3.074e-36	146.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4DRTI@85009|Propionibacteriales	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158390_k127_2626701_0	1120950.KB892759_gene6297	1.995e-254	790.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4DPQG@85009|Propionibacteriales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158390_k127_2626701_1	1068980.ARVW01000001_gene7556	1.081e-26	109.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DYUS@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158390_k127_263073_3	1032480.MLP_34400	3.167e-33	130.0	COG1403@1|root,COG1403@2|Bacteria,2I9AH@201174|Actinobacteria,4DMZA@85009|Propionibacteriales	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_263073_0	1068978.AMETH_3972	0.0	1507.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4E5FD@85010|Pseudonocardiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
SRR25158390_k127_263073_2	882082.SaccyDRAFT_3851	4.773e-44	168.0	COG2890@1|root,COG2890@2|Bacteria,2ISTB@201174|Actinobacteria,4E7JB@85010|Pseudonocardiales	201174|Actinobacteria	J	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_263073_1	882083.SacmaDRAFT_1723	1.39e-44	166.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4ECUV@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Sodium calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158390_k127_2631355_0	861299.J421_3834	5.712e-79	276.0	COG4783@1|root,COG4783@2|Bacteria,1ZSU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158390_k127_2632563_2	35754.JNYJ01000009_gene1872	2.787e-81	277.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4DIN7@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158390_k127_2632563_0	35754.JNYJ01000009_gene1873	2.537e-280	880.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DB3M@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_2632563_1	44060.JODL01000002_gene2332	1.664e-278	875.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158390_k127_2632563_3	1214101.BN159_0842	0.0004604	43.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158390_k127_2632893_1	500153.JOEK01000017_gene3323	2.283e-24	105.0	2A0M8@1|root,30NRI@2|Bacteria,2I7PN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158390_k127_2632893_2	1200792.AKYF01000003_gene206	3.957e-08	65.0	2C4H4@1|root,32X9D@2|Bacteria,1VCB6@1239|Firmicutes,4HKJT@91061|Bacilli,26TSY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2632893_0	1120950.KB892745_gene2859	1.277e-84	282.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4DPUN@85009|Propionibacteriales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158390_k127_2636447_0	1121272.KB903250_gene2584	2.646e-107	362.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4DB7A@85008|Micromonosporales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_2636447_1	1246448.ANAZ01000003_gene5197	2.82e-22	98.0	2EQWD@1|root,33IG7@2|Bacteria,2GQNK@201174|Actinobacteria	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_2647675_2	1068980.ARVW01000001_gene3122	8.151e-47	171.0	COG1695@1|root,COG1695@2|Bacteria,2IG8U@201174|Actinobacteria,4E4G2@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158390_k127_2647675_0	591158.SSMG_04942	1.205e-225	703.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria	201174|Actinobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158390_k127_2647675_1	1120950.KB892751_gene6798	1.662e-70	248.0	COG0124@1|root,COG0124@2|Bacteria,2GJXW@201174|Actinobacteria,4DQBI@85009|Propionibacteriales	201174|Actinobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2647675_3	47716.JOFH01000001_gene2333	7.88e-09	59.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria	201174|Actinobacteria	Q	Fumarylacetoacetase	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158390_k127_2649254_2	1151119.KB895496_gene3931	7.081e-62	227.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
SRR25158390_k127_2649254_1	1120950.KB892742_gene2970	3.6e-71	250.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DPF2@85009|Propionibacteriales	201174|Actinobacteria	K	RNA polymerase sigma	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_2649254_0	479431.Namu_5328	8.895e-83	275.0	2DBC4@1|root,2Z8BS@2|Bacteria,2GYBF@201174|Actinobacteria,4ERMM@85013|Frankiales	201174|Actinobacteria	S	Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid	bar	-	3.5.2.1,3.5.2.15	ko:K03383,ko:K19794	ko00240,ko00791,ko01100,ko01120,map00240,map00791,map01100,map01120	-	R02139,R05561,R10777	RC00632,RC00680,RC01423,RC03058	ko00000,ko00001,ko01000	-	-	-	Amido_AtzD_TrzD
SRR25158390_k127_2659294_5	1123320.KB889702_gene9459	2.147e-12	69.0	2EGRW@1|root,33AI2@2|Bacteria,2IQF3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
SRR25158390_k127_2659294_0	471852.Tcur_0296	1.535e-167	533.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4EHC5@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	vdh	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.23	ko:K00271	ko00280,ko01100,ko01110,ko01130,map00280,map01100,map01110,map01130	-	R01212,R01434	RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_2659294_3	1122182.KB903818_gene1997	4.231e-30	120.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4DEVR@85008|Micromonosporales	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_2659294_1	561175.KB894094_gene1520	8.026e-153	506.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4EGUX@85012|Streptosporangiales	201174|Actinobacteria	P	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	copD	GO:0008150,GO:0040007	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158390_k127_2659294_4	1448389.BAVQ01000071_gene2506	7.956e-17	91.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
SRR25158390_k127_2659294_2	1150864.MILUP08_30100	4.803e-56	205.0	2F760@1|root,33ZMF@2|Bacteria,2IRR1@201174|Actinobacteria,4DJFE@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2659294_6	1394178.AWOO02000012_gene3835	3.374e-06	59.0	COG0392@1|root,COG0392@2|Bacteria,2H84W@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158390_k127_2669756_4	649638.Trad_1394	1.204e-16	82.0	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	RHH_1
SRR25158390_k127_2669756_3	870187.Thini_1711	1.815e-42	159.0	COG1848@1|root,COG1848@2|Bacteria,1N8VX@1224|Proteobacteria,1SP0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_2669756_1	446470.Snas_4658	2.628e-148	482.0	COG1940@1|root,COG3087@1|root,COG1940@2|Bacteria,COG3087@2|Bacteria,2GJ2S@201174|Actinobacteria,4EZAQ@85014|Glycomycetales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
SRR25158390_k127_2669756_0	1298863.AUEP01000008_gene1267	8.877e-217	684.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4DP8W@85009|Propionibacteriales	201174|Actinobacteria	G	ABC transporter, ATP-binding protein	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158390_k127_2669756_2	43354.JOIJ01000008_gene2966	1.542e-47	177.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4E055@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158390_k127_2670929_9	469383.Cwoe_4879	2.07e-55	198.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158390_k127_2670929_4	1121272.KB903249_gene2344	1.593e-106	367.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4DB0A@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRR25158390_k127_2670929_3	35754.JNYJ01000011_gene813	7.321e-117	382.0	COG1175@1|root,COG1175@2|Bacteria,2GJWM@201174|Actinobacteria,4DC6R@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRR25158390_k127_2670929_2	35754.JNYJ01000011_gene812	8.04e-132	434.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4D94N@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_2670929_16	595460.RRSWK_05503	1.39e-12	79.0	COG1572@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG3420@1|root,COG4257@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG4257@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2670929_13	1386089.N865_09665	1.046e-17	89.0	COG1846@1|root,COG1846@2|Bacteria,2GXYR@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2670929_14	1380354.JIAN01000005_gene1679	2.088e-14	75.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,4F1MN@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2670929_7	1068978.AMETH_2064	4.309e-58	209.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4E84A@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_2670929_8	1206729.BAFZ01000077_gene1549	3.761e-56	201.0	COG4244@1|root,COG4244@2|Bacteria,2II9W@201174|Actinobacteria,4G94C@85025|Nocardiaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158390_k127_2670929_12	1206733.BAGC01000023_gene4652	6.692e-36	143.0	2FD1V@1|root,3454C@2|Bacteria,2IJDY@201174|Actinobacteria,4G16P@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2670929_10	1120950.KB892779_gene896	5.409e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria,4DRAR@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	sigE	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_2670929_0	1089544.KB912942_gene1796	1.162e-278	865.0	COG0520@1|root,COG0520@2|Bacteria,2GP7W@201174|Actinobacteria,4E8K5@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_2670929_1	263358.VAB18032_11180	3.745e-185	587.0	COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria,4DHG7@85008|Micromonosporales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_2670929_11	1238182.C882_0953	3.495e-37	147.0	COG1309@1|root,COG1309@2|Bacteria,1RG02@1224|Proteobacteria,2U86G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2670929_6	1415166.NONO_c34810	1.378e-66	246.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,4FYQS@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_2670929_15	1206730.BAGA01000144_gene3235	1.948e-13	81.0	2EQPB@1|root,33I99@2|Bacteria,2IKF5@201174|Actinobacteria,4FVIR@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2670929_5	1120949.KB903317_gene1647	2.678e-68	234.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DBPC@85008|Micromonosporales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_2678721_0	1123320.KB889677_gene2722	0.0	1082.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158390_k127_2678721_1	1120950.KB892764_gene5639	6.933e-38	148.0	COG3832@1|root,COG3832@2|Bacteria,2GS2W@201174|Actinobacteria,4DSAG@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
SRR25158390_k127_2680584_2	1206735.BAGG01000066_gene2859	1.816e-89	301.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,4G14U@85025|Nocardiaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158390_k127_2680584_0	1463825.JNXC01000011_gene248	9.847e-173	547.0	COG2267@1|root,COG2267@2|Bacteria,2I2KD@201174|Actinobacteria,4EF63@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	ephA	GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2680584_1	1179773.BN6_45410	3.276e-161	514.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4DYQY@85010|Pseudonocardiales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_2680584_3	1279009.ADICEAN_02603	2.108e-30	124.0	COG0657@1|root,COG0657@2|Bacteria,4NM58@976|Bacteroidetes,47SS2@768503|Cytophagia	976|Bacteroidetes	I	Steryl acetyl hydrolase	-	-	3.1.1.83	ko:K01066,ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158390_k127_2680775_5	263358.VAB18032_00475	8.344e-104	343.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria,4DCV4@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_2680775_10	402777.KB235903_gene2428	5.522e-59	206.0	COG0346@1|root,COG0346@2|Bacteria,1G661@1117|Cyanobacteria,1HFAV@1150|Oscillatoriales	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2680775_16	882083.SacmaDRAFT_5215	5.025e-22	99.0	2EP16@1|root,33GN1@2|Bacteria,2IHWQ@201174|Actinobacteria,4E68S@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2680775_12	591158.SSMG_00033	5.266e-44	165.0	2BX7X@1|root,32RMD@2|Bacteria,2IKN7@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2680775_3	44060.JODL01000015_gene5185	5.636e-115	377.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158390_k127_2680775_18	1231392.OCGS_2692	1.567e-08	68.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2TSBX@28211|Alphaproteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158390_k127_2680775_6	134676.ACPL_2014	1.979e-93	314.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4DEP9@85008|Micromonosporales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158390_k127_2680775_9	909613.UO65_3245	2.528e-67	239.0	COG2120@1|root,COG2120@2|Bacteria,2IJJ0@201174|Actinobacteria,4EAVB@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158390_k127_2680775_1	446469.Sked_12840	5.131e-138	450.0	COG4586@1|root,COG4586@2|Bacteria,2GKSX@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2680775_2	471853.Bcav_3152	1.515e-115	377.0	COG3694@1|root,COG3694@2|Bacteria,2GMBG@201174|Actinobacteria	201174|Actinobacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158390_k127_2680775_4	471853.Bcav_3151	1.422e-107	354.0	COG4587@1|root,COG4587@2|Bacteria,2GKX7@201174|Actinobacteria	201174|Actinobacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158390_k127_2680775_8	1001240.GY21_09540	2.781e-82	282.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria,4FQD8@85023|Microbacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_2680775_14	319795.Dgeo_0294	1.497e-39	151.0	COG4696@1|root,COG4696@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	XK27_03185	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Acetyltransf_3,Hydrolase_3,PRA-PH
SRR25158390_k127_2680775_17	298654.FraEuI1c_2389	7.381e-20	94.0	294G1@1|root,2ZRVU@2|Bacteria,2GYP8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2680775_15	298654.FraEuI1c_2388	1.864e-31	127.0	COG1848@1|root,COG1848@2|Bacteria,2IJ8I@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_2680775_7	1298863.AUEP01000019_gene3503	2.789e-90	306.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4DP0Z@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158390_k127_2680775_11	1306174.JODP01000005_gene1745	5.677e-50	184.0	COG3281@1|root,COG3281@2|Bacteria,2GPHW@201174|Actinobacteria	201174|Actinobacteria	G	Trehalose synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2680775_0	1306174.JODP01000006_gene3431	1.159e-229	722.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158390_k127_2680775_13	1122611.KB903943_gene1482	1.606e-42	164.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4EFXC@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158390_k127_2681630_3	882083.SacmaDRAFT_1723	8.868e-63	221.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4ECUV@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Sodium calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158390_k127_2681630_5	2074.JNYD01000023_gene1340	2.258e-54	202.0	COG2120@1|root,COG2120@2|Bacteria,2IDT2@201174|Actinobacteria,4EBAF@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158390_k127_2681630_4	1120934.KB894441_gene5648	3.265e-59	210.0	COG3265@1|root,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria,4E4C8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Carbohydrate kinase, thermoresistant glucokinase	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
SRR25158390_k127_2681630_2	1056816.JAFQ01000004_gene4573	6.904e-65	224.0	COG3832@1|root,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,4G1HM@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_2681630_0	1123023.JIAI01000001_gene7588	4.501e-104	342.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4E1UH@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_2681630_1	1246995.AFR_14755	2.573e-70	244.0	COG3832@1|root,COG3832@2|Bacteria,2IFBH@201174|Actinobacteria,4DDN4@85008|Micromonosporales	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_2681630_6	1352941.M877_21335	6.442e-52	185.0	COG0640@1|root,COG0640@2|Bacteria,2IHS2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_2681630_7	33876.JNXY01000019_gene7627	2.831e-37	149.0	2DQC6@1|root,335WC@2|Bacteria,2I2XJ@201174|Actinobacteria,4D9VA@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2993
SRR25158390_k127_2683999_7	1306174.JODP01000018_gene4503	8.923e-13	68.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158390_k127_2683999_1	471852.Tcur_3680	2.559e-148	476.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4EGEB@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	adh3	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158390_k127_2683999_5	266940.Krad_1227	2.014e-44	169.0	COG2755@1|root,COG2755@2|Bacteria,2IA8J@201174|Actinobacteria	201174|Actinobacteria	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158390_k127_2683999_3	103733.JNYO01000038_gene4159	8.405e-104	353.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4E26P@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158390_k127_2683999_6	2002.JOEQ01000012_gene5836	1.821e-24	102.0	2E460@1|root,32Z20@2|Bacteria,2GQGS@201174|Actinobacteria,4EKRA@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2683999_0	479435.Kfla_5184	0.0	1702.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DN7Q@85009|Propionibacteriales	201174|Actinobacteria	C	2-oxoglutarate dehydrogenase	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158390_k127_2683999_2	1713.JOFV01000002_gene617	1.819e-107	358.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4F0RV@85016|Cellulomonadaceae	201174|Actinobacteria	K	PFAM periplasmic binding protein LacI transcriptional regulator	celR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_2683999_4	644283.Micau_1664	4.304e-53	188.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4DBF1@85008|Micromonosporales	201174|Actinobacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
SRR25158390_k127_2701525_0	1298863.AUEP01000019_gene3551	3.102e-207	653.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4DNP0@85009|Propionibacteriales	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158390_k127_2701525_1	926564.KI911609_gene4365	1.092e-199	638.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
SRR25158390_k127_2701525_2	675635.Psed_5616	4.831e-153	489.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4DX6K@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158390_k127_2701525_5	1205910.B005_4780	4.422e-61	216.0	COG0733@1|root,COG0733@2|Bacteria,2GIU3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	metP	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SRR25158390_k127_2701525_3	566461.SSFG_04871	8.706e-153	491.0	COG0733@1|root,COG0733@2|Bacteria,2GIU3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	metP	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SRR25158390_k127_2701525_4	446470.Snas_1906	4.452e-80	274.0	COG0346@1|root,COG2154@1|root,COG0346@2|Bacteria,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158390_k127_2706280_0	644283.Micau_4703	2.033e-153	491.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DABZ@85008|Micromonosporales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158390_k127_2706280_1	1120950.KB892768_gene5268	2.267e-138	451.0	COG3835@1|root,COG3835@2|Bacteria,2I2QR@201174|Actinobacteria,4DWX2@85009|Propionibacteriales	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158390_k127_2706280_2	2045.KR76_18725	1.564e-17	84.0	COG0331@1|root,COG0511@1|root,COG0331@2|Bacteria,COG0511@2|Bacteria,2GME0@201174|Actinobacteria,4DPZC@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl transferase domain	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158390_k127_2747293_8	103733.JNYO01000019_gene2041	6.063e-70	239.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4DXP8@85010|Pseudonocardiales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158390_k127_2747293_5	1385518.N798_04275	7.255e-112	368.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4FE89@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158390_k127_2747293_7	351607.Acel_1539	4.551e-78	264.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4ESC9@85013|Frankiales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158390_k127_2747293_6	1033730.CAHG01000013_gene1367	1.495e-82	286.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4DQ6M@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158390_k127_2747293_3	1120936.KB907226_gene2855	1.855e-169	539.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4EID1@85012|Streptosporangiales	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158390_k127_2747293_13	1121924.ATWH01000002_gene3939	0.000105	54.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4FNCA@85023|Microbacteriaceae	201174|Actinobacteria	D	DivIVA protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158390_k127_2747293_10	1463841.JOIR01000022_gene3205	3.716e-41	166.0	COG0346@1|root,COG0346@2|Bacteria,2IM0I@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Glyoxalase_4
SRR25158390_k127_2747293_0	1380370.JIBA01000012_gene3619	7.471e-260	811.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4FEIW@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158390_k127_2747293_1	40571.JOEA01000005_gene4036	8.683e-257	798.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4E94P@85010|Pseudonocardiales	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_2747293_2	1386089.N865_10000	4.882e-218	685.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FESA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_2747293_11	390989.JOEG01000011_gene200	3.851e-36	143.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria,4DDQ3@85008|Micromonosporales	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2747293_9	1121272.KB903256_gene5634	8.844e-63	225.0	COG0412@1|root,COG0412@2|Bacteria,2HU8W@201174|Actinobacteria,4DCVI@85008|Micromonosporales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158390_k127_2747293_12	1157637.KB892102_gene1400	1.023e-24	114.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158390_k127_2747293_4	1463934.JOCF01000079_gene6573	4.39e-119	390.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158390_k127_2748807_4	2045.KR76_17415	5.905e-44	161.0	COG2220@1|root,COG2220@2|Bacteria,2GMFQ@201174|Actinobacteria,4DSR1@85009|Propionibacteriales	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2,Lactamase_B_3
SRR25158390_k127_2748807_3	1283299.AUKG01000001_gene3312	2.096e-55	199.0	COG1917@1|root,COG1917@2|Bacteria,2HRHC@201174|Actinobacteria,4CTH5@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_2748807_1	1394178.AWOO02000002_gene1722	1.215e-82	291.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria,4EP48@85012|Streptosporangiales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158390_k127_2748807_2	711393.AYRX01000083_gene4764	1.29e-73	254.0	2B37N@1|root,31VVP@2|Bacteria,2GWAN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158390_k127_2748807_0	103733.JNYO01000020_gene1925	2.238e-108	359.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DY2Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_2753295_6	1123023.JIAI01000005_gene459	9.289e-93	310.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
SRR25158390_k127_2753295_2	1123023.JIAI01000007_gene1953	1.683e-193	613.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158390_k127_2753295_8	1123023.JIAI01000007_gene1954	1.99e-68	240.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_2753295_1	1123023.JIAI01000007_gene1965	4.11e-205	647.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4EEMB@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158390_k127_2753295_9	675635.Psed_4919	5.774e-26	109.0	COG4311@1|root,COG4311@2|Bacteria,2GVD9@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase, delta subunit family	-	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
SRR25158390_k127_2753295_0	1123024.AUII01000011_gene4455	0.0	1134.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
SRR25158390_k127_2753295_3	1123024.AUII01000025_gene2108	6.408e-127	411.0	COG0388@1|root,COG0388@2|Bacteria,2GMSD@201174|Actinobacteria,4E2I6@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158390_k127_2753295_4	42256.RradSPS_2076	9.041e-99	332.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4CS26@84995|Rubrobacteria	84995|Rubrobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158390_k127_2753295_7	570268.ANBB01000032_gene1456	2.226e-71	256.0	COG1174@1|root,COG1174@2|Bacteria,2H9I7@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type proline glycine betaine transport systems, permease component	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158390_k127_2753295_5	1312959.KI914692_gene2794	3.669e-95	319.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,1W80J@1268|Micrococcaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158390_k127_2764881_4	882083.SacmaDRAFT_3039	1.862e-100	332.0	COG4175@1|root,COG4175@2|Bacteria,2GJC0@201174|Actinobacteria,4DX4G@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM glycine betaine L-proline transport ATP binding subunit	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158390_k127_2764881_13	661367.LLO_0471	0.0003668	48.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2764881_5	298655.KI912266_gene2101	2.915e-81	284.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
SRR25158390_k127_2764881_7	1464048.JNZS01000008_gene6137	1.302e-51	191.0	COG1651@1|root,COG1651@2|Bacteria,2GKH8@201174|Actinobacteria,4DDAG@85008|Micromonosporales	201174|Actinobacteria	O	Dsba oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158390_k127_2764881_8	58123.JOFJ01000020_gene3748	4.561e-50	185.0	2CWQV@1|root,32T07@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_2764881_10	644283.Micau_1193	1.454e-42	170.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria,4DE57@85008|Micromonosporales	201174|Actinobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
SRR25158390_k127_2764881_6	471853.Bcav_3670	1.403e-59	210.0	COG1162@1|root,COG1162@2|Bacteria,2IMZI@201174|Actinobacteria	201174|Actinobacteria	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
SRR25158390_k127_2764881_2	1033730.CAHG01000008_gene3106	6.506e-127	423.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNT3@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158390_k127_2764881_3	656024.FsymDg_0061	8.061e-112	367.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4ESC1@85013|Frankiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_2764881_1	1210045.ALNP01000022_gene244	4.505e-134	433.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158390_k127_2764881_9	882086.SacxiDRAFT_2335	6.321e-43	159.0	COG2337@1|root,COG2337@2|Bacteria,2IM6R@201174|Actinobacteria,4E5US@85010|Pseudonocardiales	201174|Actinobacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_2764881_12	882086.SacxiDRAFT_2336	3.961e-24	103.0	COG3609@1|root,COG3609@2|Bacteria,2GS33@201174|Actinobacteria,4E7DS@85010|Pseudonocardiales	201174|Actinobacteria	K	addiction module antidote protein, CC2985 family	-	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_2764881_11	1172180.KB911777_gene1629	1.229e-25	112.0	COG0454@1|root,COG0456@2|Bacteria,2INFZ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_2764881_0	1121946.AUAX01000019_gene7790	1.915e-152	498.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158390_k127_2811779_2	710111.FraQA3DRAFT_2481	9.989e-08	53.0	COG3316@1|root,COG3316@2|Bacteria,2IS60@201174|Actinobacteria	201174|Actinobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR25158390_k127_2811779_3	1125971.ASJB01000001_gene2940	6.589e-06	54.0	COG1061@1|root,COG1112@1|root,COG2251@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,2GMX8@201174|Actinobacteria,4E136@85010|Pseudonocardiales	201174|Actinobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,PDDEXK_1,RNase_H_2
SRR25158390_k127_2811779_4	875328.JDM601_0616	0.0004293	46.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2GMX8@201174|Actinobacteria,235G4@1762|Mycobacteriaceae	201174|Actinobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,PDDEXK_1,RNase_H_2
SRR25158390_k127_2811779_0	590998.Celf_3478	1.437e-66	229.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
SRR25158390_k127_2811779_1	1461580.CCAS010000028_gene2683	5.618e-15	82.0	COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus	91061|Bacilli	M	n-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Glucosaminidase,SPOR
SRR25158390_k127_2813788_7	67352.JODS01000009_gene7479	1.754e-100	333.0	COG2224@1|root,COG2224@2|Bacteria,2GNAY@201174|Actinobacteria	201174|Actinobacteria	C	Isocitrate lyase	aceA	GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158390_k127_2813788_0	1869.MB27_41745	5.227e-197	626.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,2GMWU@201174|Actinobacteria,4DGHN@85008|Micromonosporales	201174|Actinobacteria	K	IrrE N-terminal-like domain	hipB	-	-	ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
SRR25158390_k127_2813788_11	1206744.BAGL01000064_gene4445	4.914e-10	62.0	2EGDD@1|root,33A58@2|Bacteria,2GR3X@201174|Actinobacteria,4G3JS@85025|Nocardiaceae	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR25158390_k127_2813788_4	1123023.JIAI01000001_gene6637	1.027e-146	471.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DZ9U@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158390_k127_2813788_8	1384054.N790_04610	2.149e-93	317.0	2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,1S3GQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Branched-chain amino acid aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2813788_5	983917.RGE_12190	6.527e-137	442.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Aminotransferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158390_k127_2813788_6	1122933.JNIY01000003_gene577	2.652e-121	400.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4F0IF@85016|Cellulomonadaceae	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158390_k127_2813788_12	1463841.JOIR01000053_gene5430	5.312e-09	65.0	2AYU6@1|root,31QZK@2|Bacteria,2ISXJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2813788_1	1179773.BN6_80520	1.694e-173	548.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4E09A@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_2813788_3	1085623.GNIT_3021	3.267e-152	494.0	COG1073@1|root,COG1073@2|Bacteria,1QY08@1224|Proteobacteria,1SJFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2813788_2	1169154.KB897795_gene120	2.249e-159	509.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158390_k127_2813788_9	284031.JNXD01000044_gene7267	3.057e-51	184.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria	201174|Actinobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158390_k127_2813788_10	1206744.BAGL01000081_gene2581	4.717e-45	171.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4FUUX@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_2815848_1	1896.JOAU01000024_gene3555	3.417e-105	344.0	COG2224@1|root,COG2224@2|Bacteria,2GNAY@201174|Actinobacteria	201174|Actinobacteria	C	Isocitrate lyase	aceA	GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158390_k127_2815848_0	1089544.KB912942_gene4625	1.026e-231	729.0	COG2225@1|root,COG2225@2|Bacteria,2GJGP@201174|Actinobacteria,4DY8N@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158390_k127_2815848_4	234621.RER_41370	2.307e-23	106.0	COG3832@1|root,COG3832@2|Bacteria,2I51C@201174|Actinobacteria,4G1H4@85025|Nocardiaceae	201174|Actinobacteria	K	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_2815848_2	526225.Gobs_1068	1.644e-92	338.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2IAPV@201174|Actinobacteria	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_2815848_3	526225.Gobs_1069	6.031e-91	314.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4ES6Q@85013|Frankiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_2818864_6	1121019.AUMN01000013_gene4006	1.097e-28	121.0	29GVC@1|root,303T3@2|Bacteria,2IGDG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2818864_4	390989.JOEG01000012_gene3493	1.083e-42	158.0	COG2329@1|root,COG2329@2|Bacteria,2IQWX@201174|Actinobacteria,4DF12@85008|Micromonosporales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158390_k127_2818864_5	1206732.BAGD01000118_gene5271	1.161e-42	161.0	2DNTJ@1|root,32Z2U@2|Bacteria,2I8BW@201174|Actinobacteria,4GA2K@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_2818864_3	448385.sce1535	3.349e-82	286.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42QBD@68525|delta/epsilon subdivisions,2WM4P@28221|Deltaproteobacteria,2YZSV@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158390_k127_2818864_0	446470.Snas_1818	1.48e-205	651.0	COG0404@1|root,COG0404@2|Bacteria,2I8C4@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1989,GCV_T,GCV_T_C
SRR25158390_k127_2818864_2	446470.Snas_1819	9.508e-96	321.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158390_k127_2818864_1	28042.GU90_10310	1.307e-115	386.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158390_k127_2834685_8	1120950.KB892768_gene5202	3.508e-47	171.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4DN1T@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158390_k127_2834685_5	1120950.KB892768_gene5201	2.068e-140	453.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4DPCE@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158390_k127_2834685_3	1206732.BAGD01000061_gene2338	8.517e-146	476.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4FUWZ@85025|Nocardiaceae	201174|Actinobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_2834685_6	1283283.ATXA01000002_gene2660	1.337e-125	409.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158390_k127_2834685_7	266940.Krad_3156	9.441e-55	207.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158390_k127_2834685_0	1122609.AUGT01000002_gene4056	1.081e-261	811.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4DNHA@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158390_k127_2834685_1	1274.HX89_08585	1.871e-218	687.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,1ZVNC@145357|Dermacoccaceae	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158390_k127_2834685_4	1961.JOAK01000010_gene6664	9.977e-143	463.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria	201174|Actinobacteria	C	Citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRR25158390_k127_2834685_2	1440053.JOEI01000004_gene3867	3.958e-175	557.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_2840534_6	1500306.JQLA01000006_gene451	1.308e-20	96.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,4BC2G@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	abcT3	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_2840534_2	1122182.KB903834_gene6224	4.584e-119	390.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria,4DA5B@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter transmembrane region	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_2840534_7	1206725.BAFU01000068_gene5855	1.355e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4G037@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158390_k127_2840534_1	1122138.AQUZ01000038_gene7968	1.741e-283	883.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4DTAF@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
SRR25158390_k127_2840534_0	1120950.KB892708_gene4500	0.0	1040.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4DP68@85009|Propionibacteriales	201174|Actinobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158390_k127_2840534_4	196162.Noca_1286	4.4e-67	242.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4DQDM@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158390_k127_2840534_3	570268.ANBB01000035_gene2272	3.44e-69	237.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4EJ2F@85012|Streptosporangiales	201174|Actinobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158390_k127_2840534_5	1120950.KB892715_gene2452	3.989e-62	229.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4DPWU@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	pdc2	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158390_k127_2844949_6	443152.MDG893_15447	9.223e-83	279.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,1SM1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2844949_2	1463857.JOFZ01000005_gene3343	3.523e-184	582.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_2844949_5	1120949.KB903294_gene4222	1.797e-90	303.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4DCVQ@85008|Micromonosporales	201174|Actinobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR25158390_k127_2844949_3	454957.IA64_00415	3.937e-166	527.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1X45W@135614|Xanthomonadales	135614|Xanthomonadales	S	4-oxalomesaconate hydratase	fldW	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158390_k127_2844949_7	1463857.JOFZ01000005_gene3345	3.581e-46	171.0	COG0698@1|root,COG0698@2|Bacteria,2IP46@201174|Actinobacteria	201174|Actinobacteria	G	Ribose/Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	LacAB_rpiB
SRR25158390_k127_2844949_0	1449353.JQMQ01000005_gene5584	2.488e-207	648.0	2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2844949_1	1463857.JOFZ01000005_gene3353	1.981e-196	631.0	COG4819@1|root,COG4819@2|Bacteria,2IBCD@201174|Actinobacteria	201174|Actinobacteria	E	Ethanolamine utilisation protein EutA	-	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
SRR25158390_k127_2844949_4	1122609.AUGT01000023_gene572	6.862e-128	427.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DNW0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158390_k127_2844949_8	1122939.ATUD01000003_gene3434	7.482e-25	111.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4CTAW@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158390_k127_2844949_9	1123288.SOV_4c07310	1.255e-11	76.0	COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4H9IE@909932|Negativicutes	909932|Negativicutes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2845508_6	861360.AARI_19550	5.882e-08	61.0	2BEIM@1|root,3289X@2|Bacteria,2HE26@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2845508_3	66875.JODY01000008_gene2406	5.408e-68	235.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
SRR25158390_k127_2845508_0	1123320.KB889719_gene7401	1.605e-162	520.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158390_k127_2845508_5	1048339.KB913029_gene20	8.478e-46	171.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,4ET34@85013|Frankiales	201174|Actinobacteria	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158390_k127_2845508_1	1120950.KB892759_gene6237	2.13e-137	447.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4DNFX@85009|Propionibacteriales	201174|Actinobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158390_k127_2845508_2	1155714.KB891987_gene2662	1.033e-106	357.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	yngF	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_2845508_4	1033730.CAHG01000002_gene2896	1.358e-51	191.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4DPH6@85009|Propionibacteriales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cyaA	GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009268,GO:0009628,GO:0009975,GO:0009987,GO:0010851,GO:0010854,GO:0010855,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0030234,GO:0031279,GO:0031406,GO:0033293,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098772,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1264	Ad_Cy_reg,Guanylate_cyc
SRR25158390_k127_2848657_2	1179773.BN6_54010	1.758e-39	155.0	COG1309@1|root,COG1309@2|Bacteria,2HD07@201174|Actinobacteria,4DZCN@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2848657_1	345341.KUTG_07881	1.777e-64	242.0	COG1595@1|root,COG1595@2|Bacteria,2I12G@201174|Actinobacteria,4ECCQ@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2848657_0	1122138.AQUZ01000004_gene1099	3.257e-109	357.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DNZA@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158390_k127_2852357_4	101510.RHA1_ro04495	0.0008264	43.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4G9I2@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_2852357_1	1089544.KB912942_gene1686	3.624e-99	329.0	COG0842@1|root,COG0842@2|Bacteria,2H2PR@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_2852357_0	1089544.KB912942_gene1687	5.169e-131	425.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXBN@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_2852357_3	1463857.JOFZ01000008_gene495	2.76e-07	54.0	299R2@1|root,2ZWTA@2|Bacteria,2GQXP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2852357_2	28444.JODQ01000007_gene5822	1.488e-34	134.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria,4EGUG@85012|Streptosporangiales	201174|Actinobacteria	E	Helix-hairpin-helix domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRR25158390_k127_2861139_4	1869.MB27_42750	0.0001727	48.0	COG2197@1|root,COG2197@2|Bacteria,2GNUY@201174|Actinobacteria,4D8EH@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_2861139_2	1043205.AFYF01000057_gene2681	3.965e-145	472.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4FFWQ@85021|Intrasporangiaceae	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158390_k127_2861139_1	1169161.KB897717_gene3060	7.292e-175	557.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158390_k127_2861139_3	1120954.ATXE01000002_gene1319	4.862e-113	385.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DP9F@85009|Propionibacteriales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158390_k127_2861139_0	1463845.JOIG01000008_gene3714	0.0	1250.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158390_k127_286642_1	1394178.AWOO02000029_gene4654	1.274e-179	571.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4END4@85012|Streptosporangiales	201174|Actinobacteria	C	Aconitase family (aconitate hydratase)	acnA1	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158390_k127_286642_5	269800.Tfu_2515	8.461e-19	91.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4EK0K@85012|Streptosporangiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_286642_0	1343740.M271_06390	2.906e-261	820.0	COG0021@1|root,COG0021@2|Bacteria,2I36F@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the transketolase family	tkt3	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158390_k127_286642_4	935839.JAGJ01000008_gene1786	2.617e-24	117.0	COG5602@1|root,COG5602@2|Bacteria,2GRHT@201174|Actinobacteria,4F4DZ@85017|Promicromonosporaceae	201174|Actinobacteria	B	Belongs to the OprB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_286642_2	1206739.BAGJ01000256_gene22	6.073e-56	200.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria,4FUGY@85025|Nocardiaceae	201174|Actinobacteria	S	Protein involved in polyketide synthase activity and antibiotic biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158390_k127_286642_7	1394178.AWOO02000004_gene2516	3.148e-09	62.0	2EJ8W@1|root,33D03@2|Bacteria,2GW9I@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1660
SRR25158390_k127_286642_6	1298863.AUEP01000018_gene3913	6.281e-14	72.0	2EI4A@1|root,33BVN@2|Bacteria,2GX45@201174|Actinobacteria,4DSKQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_286642_3	408672.NBCG_01970	1.143e-48	188.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria,4DUCD@85009|Propionibacteriales	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
SRR25158390_k127_2869521_3	1122138.AQUZ01000030_gene4643	7.045e-127	417.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2HFU4@201174|Actinobacteria,4DPPH@85009|Propionibacteriales	201174|Actinobacteria	J	Glycyl-tRNA synthetase alpha subunit	glyS	-	6.1.1.14	ko:K01879,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA-synt_2e,tRNA_synt_2f
SRR25158390_k127_2869521_4	1463820.JOGW01000002_gene6425	1.049e-45	171.0	COG0500@1|root,COG0500@2|Bacteria,2I2UC@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_2869521_1	1120950.KB892779_gene945	2.056e-174	552.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DQ3H@85009|Propionibacteriales	201174|Actinobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158390_k127_2869521_0	68260.JOAY01000024_gene1085	4.597e-317	980.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158390_k127_2869521_5	293826.Amet_3046	6.742e-11	72.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,36FBU@31979|Clostridiaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158390_k127_2869521_2	1464048.JNZS01000007_gene4453	5.29e-155	502.0	2DBGS@1|root,2Z95N@2|Bacteria,2ICPX@201174|Actinobacteria,4DAIQ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2871935_1	512565.AMIS_73000	9.978e-16	77.0	COG4770@1|root,COG4770@2|Bacteria,2I2DF@201174|Actinobacteria,4DFRH@85008|Micromonosporales	201174|Actinobacteria	I	Biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158390_k127_2871935_0	219305.MCAG_01854	5.957e-55	198.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria,4DEF7@85008|Micromonosporales	201174|Actinobacteria	K	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_288237_4	649831.L083_5615	7.568e-88	293.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	1.13.11.1,1.13.11.37	ko:K03381,ko:K04098	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R03891,R04061,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01016,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
SRR25158390_k127_288237_1	1068978.AMETH_5219	5.308e-185	587.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4E1YM@85010|Pseudonocardiales	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158390_k127_288237_2	1463825.JNXC01000011_gene315	2.128e-136	437.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2IG6F@201174|Actinobacteria,4E68H@85010|Pseudonocardiales	201174|Actinobacteria	K	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_288237_5	1121926.AXWO01000001_gene3325	4.79e-51	185.0	COG5500@1|root,COG5500@2|Bacteria,2INAA@201174|Actinobacteria	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SRR25158390_k127_288237_6	909613.UO65_3224	6.973e-50	184.0	COG1917@1|root,COG1917@2|Bacteria,2IIQD@201174|Actinobacteria,4E5D9@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_288237_0	479432.Sros_7481	2.439e-215	687.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4EGA4@85012|Streptosporangiales	201174|Actinobacteria	OP	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158390_k127_288237_3	1121946.AUAX01000004_gene696	9.151e-130	427.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4DBWN@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_288237_7	118161.KB235922_gene5337	1.133e-14	83.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GC8T@1117|Cyanobacteria	1117|Cyanobacteria	Q	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase
SRR25158390_k127_288237_8	298653.Franean1_4484	6.677e-07	52.0	COG0410@1|root,COG0410@2|Bacteria,2HNPS@201174|Actinobacteria	2|Bacteria	E	Branched-chain amino acid transport	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_2896048_10	479432.Sros_1578	3.311e-06	58.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	Cytochrome_C554,SBP_bac_8
SRR25158390_k127_2896048_0	391037.Sare_1636	1.531e-156	507.0	COG0443@1|root,COG3266@1|root,COG0443@2|Bacteria,COG3266@2|Bacteria,2GNTE@201174|Actinobacteria,4DM1N@85008|Micromonosporales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
SRR25158390_k127_2896048_6	1278073.MYSTI_07311	6.926e-28	125.0	COG3832@1|root,COG3832@2|Bacteria,1NCAD@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_2896048_5	1144275.COCOR_07584	2.506e-29	125.0	COG0640@1|root,COG0640@2|Bacteria,1RJ39@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_2896048_7	1120950.KB892708_gene4181	9.885e-27	114.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4DS2F@85009|Propionibacteriales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2896048_2	1449353.JQMQ01000005_gene4892	6.154e-83	280.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,2NG9G@228398|Streptacidiphilus	201174|Actinobacteria	T	ANTAR	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158390_k127_2896048_9	665577.JH993790_gene3839	5.712e-08	64.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_2896048_4	269800.Tfu_1186	9.939e-67	244.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4EFRW@85012|Streptosporangiales	201174|Actinobacteria	E	Receptor family ligand binding region	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_2896048_3	1123251.ATWM01000002_gene409	7.831e-79	281.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_2896048_1	1236902.ANAS01000018_gene3270	1.299e-100	331.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4EHNQ@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_2923484_6	1122611.KB904018_gene7053	0.0008741	42.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4EGB0@85012|Streptosporangiales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_2923484_0	1108045.GORHZ_118_00650	1.826e-97	323.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4GE2H@85026|Gordoniaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_2923484_5	479431.Namu_1998	1.504e-33	143.0	2F7XJ@1|root,340BF@2|Bacteria,2H669@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2923484_2	694430.Natoc_3739	2.199e-52	195.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
SRR25158390_k127_2923484_1	2074.JNYD01000002_gene5664	2.371e-73	255.0	2BVHN@1|root,332R2@2|Bacteria,2IFVR@201174|Actinobacteria,4E51V@85010|Pseudonocardiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2923484_4	1380347.JNII01000012_gene2672	1.001e-37	151.0	COG3064@1|root,COG3064@2|Bacteria,2I5UC@201174|Actinobacteria	201174|Actinobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158390_k127_2923484_3	644966.Tmar_0770	3.331e-50	185.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,24EBI@186801|Clostridia	186801|Clostridia	S	PFAM DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158390_k127_292838_3	1120936.KB907218_gene3309	9.879e-56	203.0	COG3177@1|root,COG3177@2|Bacteria,2GIT8@201174|Actinobacteria,4EG60@85012|Streptosporangiales	201174|Actinobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158390_k127_292838_0	1048339.KB913029_gene1213	0.0	1093.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158390_k127_292838_6	928724.SacglDRAFT_03844	5.904e-12	77.0	2E39G@1|root,32Y91@2|Bacteria,2GQNT@201174|Actinobacteria,4E705@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_292838_4	1445613.JALM01000129_gene1652	3.298e-47	173.0	COG1765@1|root,COG1765@2|Bacteria,2IRWN@201174|Actinobacteria,4EF3C@85010|Pseudonocardiales	201174|Actinobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_292838_1	66373.JOFQ01000008_gene184	2.253e-114	381.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158390_k127_292838_2	1120950.KB892762_gene5462	3.992e-101	341.0	COG0455@1|root,COG0455@2|Bacteria,2GIVN@201174|Actinobacteria,4DWZF@85009|Propionibacteriales	201174|Actinobacteria	D	bacterial-type flagellum organization	cpaE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158390_k127_292838_5	1463854.JOHT01000003_gene6407	2.547e-43	163.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system protein e	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158390_k127_293526_4	675635.Psed_3024	3.576e-74	265.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158390_k127_293526_2	408672.NBCG_02725	5.927e-90	307.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_293526_3	1380347.JNII01000007_gene515	1.924e-77	263.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4EV2A@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_293526_0	1121272.KB903249_gene1622	1.847e-151	484.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4D92U@85008|Micromonosporales	201174|Actinobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158390_k127_293526_6	1120950.KB892707_gene4951	7.929e-19	92.0	293HX@1|root,2ZR01@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_293526_1	570268.ANBB01000015_gene3721	1.786e-95	318.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4EGBQ@85012|Streptosporangiales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158390_k127_293526_5	1151119.KB895492_gene1607	2.258e-26	110.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,1W8WC@1268|Micrococcaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158390_k127_2939333_7	1048339.KB913029_gene2984	2.232e-12	69.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4ESYK@85013|Frankiales	201174|Actinobacteria	S	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2939333_5	1121946.AUAX01000003_gene1845	3.863e-45	171.0	2AD1W@1|root,312Q2@2|Bacteria,2GNNN@201174|Actinobacteria,4DEDN@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2939333_1	391037.Sare_0215	3.452e-64	239.0	COG3170@1|root,COG3170@2|Bacteria,2I2VU@201174|Actinobacteria,4DD14@85008|Micromonosporales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2939333_0	1172180.KB911801_gene7804	1.411e-201	645.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_2939333_2	211114.JOEF01000009_gene1691	4.713e-59	219.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4DZV4@85010|Pseudonocardiales	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_2939333_6	208439.AJAP_14440	1.533e-16	86.0	COG5340@1|root,COG5340@2|Bacteria,2IHBZ@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158390_k127_2939333_3	1160718.SU9_02469	5.704e-53	193.0	COG1309@1|root,COG1309@2|Bacteria,2GNVS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_2939333_4	455632.SGR_1047	6.771e-46	169.0	COG3255@1|root,COG3255@2|Bacteria,2IFWK@201174|Actinobacteria,41AP2@629295|Streptomyces griseus group	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158390_k127_2940872_2	1120950.KB892745_gene2925	9.241e-79	274.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4DR6P@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_2940872_3	1237500.ANBA01000003_gene4776	1.477e-34	140.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,4EKC2@85012|Streptosporangiales	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
SRR25158390_k127_2940872_5	1123320.KB889696_gene9112	3.239e-26	111.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158390_k127_2940872_0	471852.Tcur_1568	1.59e-297	936.0	COG2366@1|root,COG2366@2|Bacteria,2GISQ@201174|Actinobacteria,4EFUH@85012|Streptosporangiales	201174|Actinobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158390_k127_2940872_1	1236902.ANAS01000014_gene1182	4.89e-166	540.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria,4EGNC@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolase family 10	tomA	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,CBM_2,CBM_4_9,Glyco_hydro_10,fn3
SRR25158390_k127_2940872_4	1120950.KB892750_gene6887	1.626e-26	110.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4DR3Y@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158390_k127_2949478_4	67281.JNZZ01000037_gene1391	1.724e-68	244.0	COG0583@1|root,COG0583@2|Bacteria,2GJFG@201174|Actinobacteria,4189Q@629295|Streptomyces griseus group	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_2949478_5	1278073.MYSTI_02419	4.947e-42	165.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_2949478_0	749414.SBI_06412	4.615e-127	413.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_2949478_3	1174528.JH992893_gene5990	9.416e-81	277.0	COG1028@1|root,COG1028@2|Bacteria,1G4S8@1117|Cyanobacteria	1117|Cyanobacteria	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.100	ko:K00059,ko:K19550	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11067,R11671	RC00029,RC00117,RC03342	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_2949478_2	1394178.AWOO02000006_gene3445	9.272e-87	295.0	COG0583@1|root,COG0583@2|Bacteria,2GJ4Z@201174|Actinobacteria,4EG6Q@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_2949478_7	1123023.JIAI01000001_gene7347	2.456e-10	70.0	COG5516@1|root,COG5516@2|Bacteria,2GP70@201174|Actinobacteria,4E614@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158390_k127_2949478_6	500153.JOEK01000002_gene321	1.309e-24	105.0	COG0662@1|root,COG0662@2|Bacteria,2IHQ8@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_2949478_1	479434.Sthe_2520	2.476e-95	329.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,27Y0A@189775|Thermomicrobia	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_2963110_15	2045.KR76_14055	4.607e-19	91.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4DS3V@85009|Propionibacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158390_k127_2963110_8	1210045.ALNP01000010_gene1150	8.151e-123	398.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158390_k127_2963110_4	888056.HMPREF9062_1576	5.488e-158	511.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4D3JI@85005|Actinomycetales	201174|Actinobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158390_k127_2963110_2	35754.JNYJ01000012_gene979	3.215e-165	527.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D98B@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158390_k127_2963110_3	1386089.N865_08240	5.691e-165	527.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4FEE7@85021|Intrasporangiaceae	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158390_k127_2963110_7	471852.Tcur_2196	2.446e-123	402.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4EHPS@85012|Streptosporangiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158390_k127_2963110_10	479435.Kfla_3256	7.052e-100	336.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4DPVQ@85009|Propionibacteriales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158390_k127_2963110_1	1120950.KB892793_gene2370	1.794e-293	914.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4DN4X@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158390_k127_2963110_14	55952.BU52_17710	2.018e-33	138.0	COG2146@1|root,COG2146@2|Bacteria,2IKSY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158390_k127_2963110_0	1048339.KB913029_gene4399	0.0	1592.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ERXD@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158390_k127_2963110_12	369723.Strop_3113	6.54e-58	210.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria,4D9XX@85008|Micromonosporales	201174|Actinobacteria	G	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_2963110_9	479435.Kfla_3238	1.258e-103	340.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,4DPUP@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_2963110_11	446470.Snas_4466	1.661e-89	303.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria	201174|Actinobacteria	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158390_k127_2963110_6	477641.MODMU_3655	4.789e-130	423.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4ERNE@85013|Frankiales	201174|Actinobacteria	P	membrane protein, TerC	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158390_k127_2963110_13	1464048.JNZS01000019_gene2350	3.781e-49	178.0	COG2315@1|root,COG2315@2|Bacteria,2HR7I@201174|Actinobacteria,4DFE0@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_2963110_5	1048339.KB913029_gene4503	8.74e-138	442.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4ERJA@85013|Frankiales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158390_k127_2973155_1	1120950.KB892708_gene4491	3.263e-42	158.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4DQUX@85009|Propionibacteriales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158390_k127_2973155_0	1050202.KB913024_gene2110	5.47e-61	214.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,408JV@622450|Actinopolysporales	201174|Actinobacteria	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158390_k127_2973155_3	1385520.N802_15265	1.831e-06	55.0	2BFEQ@1|root,3238M@2|Bacteria,2GXRZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2973155_2	1304865.JAGF01000001_gene181	1.503e-33	132.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4F0PA@85016|Cellulomonadaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_2986919_6	1121946.AUAX01000021_gene8049	2.025e-107	354.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DB6P@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_2986919_1	1429046.RR21198_1146	3.982e-141	463.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4G8KN@85025|Nocardiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
SRR25158390_k127_2986919_10	1120950.KB892739_gene3897	5.324e-44	171.0	28U7D@1|root,33Z48@2|Bacteria,2IPM9@201174|Actinobacteria,4DV9K@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2986919_0	1120950.KB892739_gene3896	1.977e-285	891.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DP2B@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_2986919_4	1299327.I546_6551	1.578e-110	368.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,233UI@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2986919_7	1278073.MYSTI_07895	1.215e-84	289.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42T8W@68525|delta/epsilon subdivisions,2WPDG@28221|Deltaproteobacteria,2YWUZ@29|Myxococcales	28221|Deltaproteobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_2986919_3	1121272.KB903290_gene4616	9.607e-128	421.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4DM5R@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_2986919_9	1157637.KB892090_gene6465	1.125e-66	239.0	COG0030@1|root,COG0030@2|Bacteria,2H1TK@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermA	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
SRR25158390_k127_2986919_12	1123258.AQXZ01000017_gene3865	1.271e-22	104.0	COG1714@1|root,COG1714@2|Bacteria,2GS9U@201174|Actinobacteria,4G38W@85025|Nocardiaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_2986919_11	43759.JNWK01000032_gene4271	3.05e-29	121.0	arCOG03175@1|root,32RFA@2|Bacteria,2IFE3@201174|Actinobacteria	201174|Actinobacteria	S	Sporulation and cell division protein SsgA	ssgB	GO:0000003,GO:0000910,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006725,GO:0006732,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009653,GO:0009987,GO:0010564,GO:0010927,GO:0016043,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0018958,GO:0019438,GO:0019748,GO:0019752,GO:0019954,GO:0022402,GO:0022607,GO:0030154,GO:0030312,GO:0030428,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030638,GO:0030639,GO:0031160,GO:0032465,GO:0032467,GO:0032502,GO:0032506,GO:0032989,GO:0032991,GO:0040007,GO:0042180,GO:0042181,GO:0042221,GO:0042244,GO:0042546,GO:0043436,GO:0043648,GO:0043650,GO:0043934,GO:0043936,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044457,GO:0044464,GO:0044550,GO:0045229,GO:0045787,GO:0046189,GO:0046394,GO:0046483,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051301,GO:0051302,GO:0051716,GO:0051726,GO:0051781,GO:0065007,GO:0070590,GO:0070726,GO:0070887,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0090068,GO:0090529,GO:1901110,GO:1901112,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1902074,GO:1902075,GO:1903664,GO:1903666,GO:1990586,GO:2000241,GO:2000243,GO:2000244,GO:2000246	-	-	-	-	-	-	-	-	-	-	SsgA
SRR25158390_k127_2986919_8	443255.SCLAV_0769	5.919e-68	240.0	COG5516@1|root,COG5516@2|Bacteria,2GNZF@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158390_k127_2986919_5	1206101.AZXC01000012_gene1092	1.025e-107	355.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158390_k127_2986919_2	1133850.SHJG_2968	9.927e-136	444.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria	201174|Actinobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158390_k127_2993459_0	1380390.JIAT01000013_gene123	9.383e-252	797.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158390_k127_2993459_4	35754.JNYJ01000020_gene289	1.864e-107	355.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158390_k127_2993459_8	1298863.AUEP01000005_gene2466	8.582e-78	267.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,4DV2T@85009|Propionibacteriales	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158390_k127_2993459_7	1298863.AUEP01000005_gene2467	6.378e-89	298.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria,4DV4X@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158390_k127_2993459_6	479434.Sthe_2526	1.413e-97	351.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
SRR25158390_k127_2993459_2	1957.JODX01000002_gene4558	7.489e-221	701.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158390_k127_2993459_5	1121946.AUAX01000012_gene6587	1.24e-104	346.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4DBP6@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158390_k127_2993459_10	269800.Tfu_0458	1.831e-48	184.0	COG0741@1|root,COG0741@2|Bacteria,2GM11@201174|Actinobacteria,4EJ12@85012|Streptosporangiales	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158390_k127_2993459_1	1120950.KB892823_gene569	1.665e-225	705.0	COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4DNRD@85009|Propionibacteriales	201174|Actinobacteria	T	phosphate starvation-inducible protein PhoH	phoH2	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SRR25158390_k127_2993459_3	1193181.BN10_920054	4.711e-116	378.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4FFWU@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS1	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158390_k127_2993459_9	1120950.KB892779_gene981	3.205e-52	187.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DQ8R@85009|Propionibacteriales	201174|Actinobacteria	S	Haemolysin-III related	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158390_k127_2995114_1	882083.SacmaDRAFT_2027	8.427e-103	344.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_2995114_3	1173028.ANKO01000075_gene2969	2.625e-22	104.0	COG3631@1|root,COG3631@2|Bacteria,1GAK6@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158390_k127_2995114_2	1123024.AUII01000015_gene3750	1.59e-97	336.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
SRR25158390_k127_2995114_0	1380390.JIAT01000009_gene1628	6.393e-107	382.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_3008159_1	1304872.JAGC01000009_gene837	1.061e-68	241.0	COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,42RYU@68525|delta/epsilon subdivisions,2WNVI@28221|Deltaproteobacteria,2M9M7@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
SRR25158390_k127_3008159_0	477641.MODMU_4784	3.637e-159	514.0	COG2319@1|root,COG3391@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3391@2|Bacteria,COG3629@2|Bacteria,2GJN3@201174|Actinobacteria,4ES8H@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,PD40,Trans_reg_C,WD40
SRR25158390_k127_3008924_3	1463864.JOGO01000009_gene405	9.871e-122	397.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_3008924_5	1298863.AUEP01000005_gene2528	4.241e-24	109.0	COG0776@1|root,COG0776@2|Bacteria,2GTF6@201174|Actinobacteria,4DS6N@85009|Propionibacteriales	201174|Actinobacteria	L	regulation of translation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3008924_0	882086.SacxiDRAFT_0099	4.717e-316	983.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158390_k127_3008924_6	1464048.JNZS01000004_gene1622	5.409e-20	97.0	COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4DFRB@85008|Micromonosporales	201174|Actinobacteria	P	PFAM Heavy metal transport detoxification protein	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
SRR25158390_k127_3008924_2	1123023.JIAI01000008_gene1381	1.348e-127	415.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4DZ7M@85010|Pseudonocardiales	201174|Actinobacteria	O	C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_3008924_1	450380.JPSY01000001_gene519	2.649e-201	656.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4FKPT@85023|Microbacteriaceae	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_3008924_4	298654.FraEuI1c_7039	3.634e-78	274.0	COG1940@1|root,COG1940@2|Bacteria,2GPEI@201174|Actinobacteria,4EX83@85013|Frankiales	201174|Actinobacteria	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158390_k127_3010812_2	882083.SacmaDRAFT_0004	4.335e-100	329.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4DYVC@85010|Pseudonocardiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158390_k127_3010812_1	67352.JODS01000003_gene1917	1.339e-138	451.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158390_k127_3010812_0	1120950.KB892740_gene2520	4.546e-199	632.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4DMZ1@85009|Propionibacteriales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158390_k127_3010812_9	1043205.AFYF01000034_gene179	3.496e-13	72.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4FHTP@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158390_k127_3010812_7	996637.SGM_3528	9.675e-27	115.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158390_k127_3010812_8	1043205.AFYF01000034_gene177	1.529e-20	96.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4FHQY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158390_k127_3010812_3	1120950.KB892740_gene2522	5.253e-91	312.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4DNB3@85009|Propionibacteriales	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158390_k127_3010812_5	479433.Caci_9052	1.468e-60	213.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria	201174|Actinobacteria	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158390_k127_3010812_4	1894.JOER01000011_gene2116	1.089e-68	240.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158390_k127_3010812_6	1123322.KB904669_gene3627	1.759e-31	131.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria	201174|Actinobacteria	D	chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158390_k127_3023774_2	882086.SacxiDRAFT_3056	0.000308	49.0	2F3VX@1|root,33WN4@2|Bacteria,2GTDN@201174|Actinobacteria,4E5QN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3023774_0	1155718.KB891880_gene5143	0.0	1232.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158390_k127_3023774_1	1120950.KB892739_gene3958	4.193e-81	273.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DNZA@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158390_k127_3040012_0	1121106.JQKB01000014_gene5732	7.296e-54	195.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,2JUB7@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158390_k127_3040012_1	1095767.CAHD01000130_gene1287	8.408e-46	182.0	COG1404@1|root,COG1404@2|Bacteria,2GNIX@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158390_k127_3041701_0	1123320.KB889585_gene1788	5.859e-150	481.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	opuCA	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158390_k127_3041701_6	543632.JOJL01000016_gene8945	3.145e-07	58.0	2DRQG@1|root,33CMQ@2|Bacteria,2IFEG@201174|Actinobacteria,4DEJ0@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF3180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3180
SRR25158390_k127_3041701_3	1032480.MLP_48430	5.494e-57	205.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4DQ88@85009|Propionibacteriales	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158390_k127_3041701_5	1449355.JQNR01000005_gene2446	1.509e-44	164.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158390_k127_3041701_1	68260.JOAY01000038_gene2285	2.345e-108	358.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158390_k127_3041701_2	479433.Caci_8425	9.775e-92	305.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158390_k127_3041701_4	1120950.KB892801_gene1716	1.606e-47	174.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4DP9B@85009|Propionibacteriales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158390_k127_306616_2	1068978.AMETH_3992	2.865e-123	398.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158390_k127_306616_0	477641.MODMU_2918	2.931e-211	674.0	COG0747@1|root,COG0747@2|Bacteria,2IJYA@201174|Actinobacteria,4EUAH@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_306616_1	882083.SacmaDRAFT_4010	3.068e-127	415.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4E0BP@85010|Pseudonocardiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_3074870_0	479433.Caci_6711	1.348e-194	610.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria	201174|Actinobacteria	IQ	Rhamnulose-1-phosphate aldolase alcohol dehydrogenase	rhaD	-	1.1.1.1,1.1.1.140,4.1.2.19	ko:K00001,ko:K00068,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R05607,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short_C2
SRR25158390_k127_3074870_6	749927.AMED_5776	1.857e-19	90.0	COG2197@1|root,COG2197@2|Bacteria,2GXWZ@201174|Actinobacteria,4E7PH@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_3074870_1	1380347.JNII01000005_gene3190	8.857e-182	585.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4EUG0@85013|Frankiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158390_k127_3074870_7	1246448.ANAZ01000005_gene5091	1.424e-08	59.0	COG3408@1|root,COG3408@2|Bacteria,2H2QX@201174|Actinobacteria,4ER9P@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
SRR25158390_k127_3074870_2	926569.ANT_01780	1.115e-164	529.0	COG1653@1|root,COG1653@2|Bacteria,2G5UT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117,ko:K17315	ko02010,map02010	M00196,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_3074870_4	926569.ANT_01790	1.217e-110	365.0	COG1175@1|root,COG1175@2|Bacteria,2G5W9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRR25158390_k127_3074870_5	171693.BN988_02214	1.296e-105	355.0	COG0395@1|root,COG0395@2|Bacteria,1UZFM@1239|Firmicutes,4IQN6@91061|Bacilli,23KP2@182709|Oceanobacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
SRR25158390_k127_3074870_3	525909.Afer_1577	3.966e-121	417.0	COG0642@1|root,COG1129@1|root,COG1129@2|Bacteria,COG2205@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158390_k127_3080095_11	1048339.KB913029_gene4289	8.258e-63	241.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4ESD4@85013|Frankiales	201174|Actinobacteria	P	the ABC transporter	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158390_k127_3080095_2	1048339.KB913029_gene4288	1.941e-168	546.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria,4ESTI@85013|Frankiales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158390_k127_3080095_3	136273.GY22_04875	2.314e-115	381.0	COG1840@1|root,COG1840@2|Bacteria,2HG0E@201174|Actinobacteria,1W88T@1268|Micrococcaceae	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158390_k127_3080095_5	1048339.KB913029_gene4283	8.964e-113	383.0	2DNJB@1|root,32XT8@2|Bacteria,2H1A6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3080095_8	1120950.KB892707_gene4739	7.546e-95	331.0	2AUNZ@1|root,31KBW@2|Bacteria,2GP4I@201174|Actinobacteria,4DR8R@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786
SRR25158390_k127_3080095_0	469383.Cwoe_1139	3.607e-245	763.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4CPST@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_3080095_4	1068980.ARVW01000001_gene3433	4.363e-114	374.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4E01J@85010|Pseudonocardiales	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3080095_10	1122609.AUGT01000018_gene143	2.246e-78	271.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria,4DNI8@85009|Propionibacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
SRR25158390_k127_3080095_9	314232.SKA53_12748	2.872e-88	299.0	COG0765@1|root,COG0765@2|Bacteria,1N786@1224|Proteobacteria,2U10S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158390_k127_3080095_7	1179773.BN6_82620	2.304e-100	347.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4E109@85010|Pseudonocardiales	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158390_k127_3080095_1	1032480.MLP_29440	1.08e-233	736.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4DNB4@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158390_k127_3080095_12	105420.BBPO01000030_gene6683	5.438e-09	59.0	2C7EP@1|root,2ZXNX@2|Bacteria,2IQ7Y@201174|Actinobacteria,2NJFP@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3080095_6	1120950.KB892741_gene2662	7.723e-112	364.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4DN5B@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_3081190_2	471857.Svir_05520	2.604e-19	92.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4E31D@85010|Pseudonocardiales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_3081190_1	1121377.KB906402_gene3314	2.6e-43	162.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	marR1	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
SRR25158390_k127_3081190_0	1128421.JAGA01000003_gene3550	3.781e-164	528.0	COG0277@1|root,COG0277@2|Bacteria,2NQTQ@2323|unclassified Bacteria	2|Bacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_308407_1	526225.Gobs_1069	3.478e-81	283.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4ES6Q@85013|Frankiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158390_k127_308407_0	298653.Franean1_3408	5.496e-101	336.0	COG3316@1|root,COG3316@2|Bacteria,2IS60@201174|Actinobacteria	201174|Actinobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR25158390_k127_308407_2	479431.Namu_3455	3.517e-06	51.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4EVNF@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_3108720_0	1122138.AQUZ01000006_gene1233	1.025e-161	514.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4DPQE@85009|Propionibacteriales	201174|Actinobacteria	G	Protein of unknown function (DUF3417)	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158390_k127_3108720_1	1120950.KB892741_gene2616	3.198e-58	207.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4DPSB@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158390_k127_3118510_0	263358.VAB18032_18850	4.643e-111	371.0	COG2936@1|root,COG2936@2|Bacteria,2GJ2K@201174|Actinobacteria,4D9JN@85008|Micromonosporales	201174|Actinobacteria	E	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
SRR25158390_k127_3118510_1	1184609.KILIM_005_01550	3.653e-69	242.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4F6W4@85018|Dermatophilaceae	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158390_k127_3118510_2	1211815.CBYP010000060_gene3113	3.385e-24	104.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4ERHG@85013|Frankiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158390_k127_3127484_0	1157634.KB912966_gene2119	1.421e-302	935.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_3129998_0	935837.JAEK01000003_gene4108	0.0	1130.0	COG3408@1|root,COG3408@2|Bacteria,1UQ28@1239|Firmicutes,4HT8H@91061|Bacilli	91061|Bacilli	G	Bacterial Ig-like domain (group 4)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,FIVAR,SLH
SRR25158390_k127_3129998_1	1003200.AXXA_04266	1.299e-129	421.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2W1SZ@28216|Betaproteobacteria,3T6IE@506|Alcaligenaceae	28216|Betaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	yhdN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_3129998_4	543632.JOJL01000017_gene9935	2.435e-34	134.0	COG5587@1|root,COG5587@2|Bacteria	2|Bacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158390_k127_3129998_2	543632.JOJL01000017_gene9933	6.645e-110	365.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_3129998_7	1230457.C476_15343	1.58e-19	99.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota,23TGQ@183963|Halobacteria	183963|Halobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_3129998_5	1463903.JOIZ01000003_gene1745	8.297e-34	140.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_3129998_3	710421.Mycch_4193	4.402e-79	275.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,233G9@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3142302_8	1172181.KB911748_gene443	1.658e-47	179.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria	201174|Actinobacteria	S	phosphoribosyltransferase	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158390_k127_3142302_5	67257.JODR01000017_gene4536	2.127e-74	257.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158390_k127_3142302_1	1312959.KI914621_gene2389	4.746e-234	733.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,1W882@1268|Micrococcaceae	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.3.17,1.1.99.1	ko:K00108,ko:K17755	ko00260,ko01100,map00260,map01100	M00555	R01022,R01025,R08211,R08212	RC00080,RC00087,RC00651	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158390_k127_3142302_2	1117647.M5M_15030	4.695e-191	638.0	COG1404@1|root,COG1404@2|Bacteria,1R6X8@1224|Proteobacteria,1SYRF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8,fn3_5
SRR25158390_k127_3142302_9	103733.JNYO01000029_gene843	7.906e-16	93.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DZS9@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
SRR25158390_k127_3142302_3	644283.Micau_1397	5.217e-163	520.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4D9EF@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158390_k127_3142302_6	1121272.KB903283_gene4935	7.731e-72	255.0	COG1733@1|root,COG1733@2|Bacteria,2I9HE@201174|Actinobacteria,4DIGA@85008|Micromonosporales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_3142302_7	1227499.C493_19546	2.994e-49	188.0	COG0500@1|root,arCOG01783@2157|Archaea,2XWBW@28890|Euryarchaeota,23UCS@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_3142302_10	67281.JNZZ01000019_gene167	5.612e-15	76.0	28VMH@1|root,2ZHPN@2|Bacteria,2GQY2@201174|Actinobacteria,41BHR@629295|Streptomyces griseus group	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3142302_0	397278.JOJN01000001_gene2978	1.32e-247	774.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4DPKA@85009|Propionibacteriales	201174|Actinobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158390_k127_3142302_4	1380370.JIBA01000014_gene2083	8.327e-128	415.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4FFJ0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158390_k127_3153252_2	1274.HX89_03380	1.238e-141	466.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,1ZVK1@145357|Dermacoccaceae	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158390_k127_3153252_3	479435.Kfla_1561	5.391e-124	406.0	COG1215@1|root,COG1215@2|Bacteria,2GMWF@201174|Actinobacteria,4DQ16@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 21	exoA	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158390_k127_3153252_4	1120950.KB892759_gene6262	2.521e-102	351.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4DPE8@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158390_k127_3153252_5	1120950.KB892759_gene6261	1.906e-92	321.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DPY2@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158390_k127_3153252_1	500153.JOEK01000018_gene3019	2.156e-190	604.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158390_k127_3153252_0	269800.Tfu_1647	3.72e-191	604.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EHDP@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	acdA3	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3153252_7	443218.AS9A_3074	9.725e-60	224.0	COG5340@1|root,COG5340@2|Bacteria,2H6VP@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_3153252_8	1386089.N865_11345	5.575e-48	177.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4FGPZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158390_k127_3153252_6	1172180.KB911776_gene879	5.545e-66	230.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria	201174|Actinobacteria	KT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
SRR25158390_k127_3153252_9	1223523.H340_01689	3.706e-30	123.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria	201174|Actinobacteria	KT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
SRR25158390_k127_3153252_10	196162.Noca_4053	3.222e-24	113.0	2E4WR@1|root,32ZQT@2|Bacteria,2GSGR@201174|Actinobacteria,4DRRE@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158390_k127_315637_2	1463861.JNXE01000007_gene1064	9.229e-11	64.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
SRR25158390_k127_315637_3	172045.KS04_09470	6.976e-06	50.0	2CIH2@1|root,2ZTG0@2|Bacteria,4NNM2@976|Bacteroidetes,1I267@117743|Flavobacteriia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158390_k127_315637_0	1122138.AQUZ01000001_gene1789	1.814e-97	321.0	COG0262@1|root,COG0262@2|Bacteria,2I9MN@201174|Actinobacteria,4DUED@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_315637_1	1128421.JAGA01000001_gene2297	5.24e-88	296.0	COG0262@1|root,COG0262@2|Bacteria,2NRYY@2323|unclassified Bacteria	2|Bacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_3167561_11	65093.PCC7418_2749	8.244e-13	69.0	COG2936@1|root,COG2936@2|Bacteria,1G1U8@1117|Cyanobacteria	1117|Cyanobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158390_k127_3167561_5	1122139.KB907864_gene2129	2.39e-130	432.0	COG1181@1|root,COG1181@2|Bacteria,1R4RC@1224|Proteobacteria,1T297@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,CPSase_L_D2
SRR25158390_k127_3167561_10	1122182.KB903813_gene2217	1.078e-29	125.0	COG0745@1|root,COG0745@2|Bacteria,2ISUN@201174|Actinobacteria,4DFDK@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Trans_reg_C
SRR25158390_k127_3167561_1	219305.MCAG_00627	5.484e-299	967.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HU5X@201174|Actinobacteria,4DBT0@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cleaved_Adhesin,Kelch_1,Peptidase_S8
SRR25158390_k127_3167561_0	649831.L083_5660	0.0	1032.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DAKK@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_3167561_2	479432.Sros_4600	9.624e-256	820.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,GAF,GAF_2,GGDEF,GerE,Pkinase,TPR_19
SRR25158390_k127_3167561_4	266117.Rxyl_2662	1.339e-138	458.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR25158390_k127_3167561_9	408672.NBCG_04611	3.2e-31	142.0	28K27@1|root,2Z9RK@2|Bacteria,2I942@201174|Actinobacteria,4DWE9@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3167561_7	743718.Isova_2973	6.322e-97	324.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4F3VH@85017|Promicromonosporaceae	201174|Actinobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_3167561_3	743718.Isova_2972	1.576e-155	503.0	COG0642@1|root,COG2205@2|Bacteria,2GK7K@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_3167561_6	743718.Isova_2971	6.47e-100	335.0	COG2358@1|root,COG2358@2|Bacteria,2GKQJ@201174|Actinobacteria	201174|Actinobacteria	S	TRAP transporter solute receptor TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158390_k127_3167561_8	1283299.AUKG01000002_gene4021	7.774e-64	228.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4CS7T@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158390_k127_3246193_1	1121926.AXWO01000019_gene1870	1.8e-75	258.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4EZJS@85014|Glycomycetales	201174|Actinobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3246193_2	1032480.MLP_13020	3.055e-62	218.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DRXP@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158390_k127_3246193_0	644283.Micau_0324	6.957e-78	266.0	COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,4DBQI@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3246193_3	512565.AMIS_1750	6.246e-26	117.0	COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,4DC7Z@85008|Micromonosporales	201174|Actinobacteria	V	Efflux ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3259422_4	1463821.JOGR01000004_gene2456	1.551e-33	133.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	cebF	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
SRR25158390_k127_3259422_0	1121926.AXWO01000008_gene2854	5.866e-216	677.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K10240	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_3259422_1	1120950.KB892743_gene3128	5.098e-114	375.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4DNHJ@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3259422_3	1121946.AUAX01000039_gene5750	8.785e-49	179.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4DG01@85008|Micromonosporales	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158390_k127_3259422_2	582899.Hden_0713	5.071e-51	186.0	COG3554@1|root,COG3554@2|Bacteria,1RHFQ@1224|Proteobacteria,2U9RI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3259422_5	266265.Bxe_B1793	1.267e-32	135.0	COG3554@1|root,COG3554@2|Bacteria,1RH4E@1224|Proteobacteria,2W3GX@28216|Betaproteobacteria,1K0GJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158390_k127_3263191_7	1123023.JIAI01000019_gene2184	1.849e-11	66.0	COG2411@1|root,COG2411@2|Bacteria,2IN3A@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3263191_2	1385521.N803_00980	8.737e-109	357.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4FFTT@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158390_k127_3263191_1	351607.Acel_1507	8.957e-176	571.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4ERHK@85013|Frankiales	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158390_k127_3263191_0	500153.JOEK01000016_gene3468	0.0	1142.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158390_k127_3263191_6	1237500.ANBA01000002_gene5837	1.348e-35	137.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4EK2G@85012|Streptosporangiales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158390_k127_3263191_3	1089455.MOPEL_032_00640	1.56e-98	331.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4F684@85018|Dermatophilaceae	201174|Actinobacteria	H	Riboflavin kinase	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158390_k127_3263191_4	443218.AS9A_2840	1.693e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,2IMHK@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3263191_5	1283283.ATXA01000005_gene2059	2.641e-44	168.0	2A651@1|root,30UXH@2|Bacteria,2IERM@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_326697_5	253839.SSNG_02337	2.269e-107	355.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158390_k127_326697_4	1120950.KB892766_gene5096	4.117e-209	659.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4DNZK@85009|Propionibacteriales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158390_k127_326697_10	1048339.KB913029_gene4851	1.887e-41	156.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4ESYQ@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158390_k127_326697_12	1122609.AUGT01000005_gene1624	5.015e-37	141.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4DRJ6@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158390_k127_326697_3	479432.Sros_7272	1.156e-229	747.0	COG1530@1|root,COG3266@1|root,COG1530@2|Bacteria,COG3266@2|Bacteria,2GMM5@201174|Actinobacteria,4EGIT@85012|Streptosporangiales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158390_k127_326697_7	1122138.AQUZ01000017_gene6534	1.325e-69	248.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,4DQ75@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158390_k127_326697_1	471852.Tcur_1544	0.0	1174.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4EFRZ@85012|Streptosporangiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_326697_9	1454010.JEOE01000001_gene594	2.434e-47	186.0	2EJ40@1|root,33CVA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_326697_15	888056.HMPREF9062_0266	3.256e-27	113.0	2ET2Q@1|root,33KKV@2|Bacteria,2H0TN@201174|Actinobacteria,4D6C7@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
SRR25158390_k127_326697_17	1288079.AUKN01000008_gene5912	9.479e-08	65.0	COG5651@1|root,COG5651@2|Bacteria,2GJ18@201174|Actinobacteria	201174|Actinobacteria	N	PPE family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_326697_0	1095767.CAHD01000204_gene2210	0.0	1528.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4F0IN@85016|Cellulomonadaceae	201174|Actinobacteria	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR25158390_k127_326697_2	1454010.JEOE01000001_gene587	4.536e-231	748.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria	201174|Actinobacteria	NU	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158390_k127_326697_14	1095767.CAHD01000203_gene2335	2.076e-31	134.0	2E4ST@1|root,32ZM5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158390_k127_326697_13	1306174.JODP01000021_gene278	2.157e-32	138.0	COG4961@1|root,COG4961@2|Bacteria,2GRCJ@201174|Actinobacteria	201174|Actinobacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158390_k127_326697_11	1095767.CAHD01000203_gene2333	7.351e-41	154.0	2E9PN@1|root,333W1@2|Bacteria	2|Bacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158390_k127_326697_6	1095767.CAHD01000203_gene2331	5.526e-94	321.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158390_k127_326697_8	1380354.JIAN01000005_gene2691	1.986e-67	232.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria	201174|Actinobacteria	U	type II secretion system	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158390_k127_3268044_1	1120950.KB892779_gene945	2.276e-131	421.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DQ3H@85009|Propionibacteriales	201174|Actinobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158390_k127_3268044_0	67352.JODS01000007_gene4611	1.172e-245	765.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158390_k127_3277144_6	680198.SCAB_4321	1.186e-70	247.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NmrA family protein	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
SRR25158390_k127_3277144_9	1237500.ANBA01000008_gene232	1.418e-51	185.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4EJHN@85012|Streptosporangiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_3277144_10	1283283.ATXA01000052_gene4084	2.218e-44	163.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4ET62@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_3277144_12	479435.Kfla_0420	7.033e-22	109.0	COG3832@1|root,COG3832@2|Bacteria,2IFFI@201174|Actinobacteria,4DUX3@85009|Propionibacteriales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_3277144_14	1122611.KB904000_gene8138	4.218e-11	75.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4EPGT@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_3277144_13	1122138.AQUZ01000034_gene6387	4.755e-14	80.0	2F5SE@1|root,33YB9@2|Bacteria,2H5GX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3277144_11	1172185.KB911523_gene3591	3.539e-27	113.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HTH_34
SRR25158390_k127_3277144_0	1137271.AZUM01000002_gene2615	5.781e-176	562.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4E28P@85010|Pseudonocardiales	201174|Actinobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N,PRC
SRR25158390_k127_3277144_3	35754.JNYJ01000004_gene5902	2.874e-97	329.0	COG1051@1|root,COG1051@2|Bacteria,2IBER@201174|Actinobacteria,4DAA2@85008|Micromonosporales	201174|Actinobacteria	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158390_k127_3277144_5	1156844.KB891831_gene4885	1.802e-76	268.0	COG3300@1|root,COG3300@2|Bacteria,2GMG6@201174|Actinobacteria	201174|Actinobacteria	T	PFAM MHYT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MHYT
SRR25158390_k127_3277144_8	1068978.AMETH_5333	4.038e-57	201.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria,4E51C@85010|Pseudonocardiales	201174|Actinobacteria	P	TIGRFAM deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_3277144_4	471853.Bcav_0882	5.947e-80	273.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158390_k127_3277144_2	1123322.KB904692_gene4489	4.844e-128	420.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3332	Amidohydro_1
SRR25158390_k127_3277144_7	1449069.JMLO01000011_gene2487	5.912e-70	244.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4G06V@85025|Nocardiaceae	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3277144_1	1120950.KB892779_gene974	1.476e-174	557.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DPGF@85009|Propionibacteriales	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158390_k127_3277144_15	1229203.KI301992_gene170	5.401e-05	46.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,3UWKA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158390_k127_3281493_0	667014.Thein_2196	3.829e-199	627.0	COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_3281493_1	211114.JOEF01000004_gene6793	1.819e-19	89.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4DY1Y@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_3281493_2	1157637.KB892144_gene2581	2.968e-16	83.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158390_k127_3288826_5	1288079.AUKN01000006_gene2815	1.102e-156	501.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_3288826_14	2074.JNYD01000035_gene6729	1.261e-90	307.0	COG0697@1|root,COG0697@2|Bacteria,2GVE1@201174|Actinobacteria,4E3UP@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_3288826_23	1828.JOKB01000041_gene4003	1.49e-58	209.0	COG1309@1|root,COG1309@2|Bacteria,2ICWK@201174|Actinobacteria,4FYCD@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3288826_1	1033730.CAHG01000008_gene3124	3.717e-243	761.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DN2S@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158390_k127_3288826_13	1234364.AMSF01000059_gene953	2.572e-95	317.0	COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,1RPCK@1236|Gammaproteobacteria,1X3GC@135614|Xanthomonadales	135614|Xanthomonadales	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158390_k127_3288826_3	1454010.JEOE01000002_gene435	2.965e-172	551.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4F0HV@85016|Cellulomonadaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_3288826_22	926564.KI911681_gene5697	1.576e-59	213.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158390_k127_3288826_26	1120950.KB892832_gene4015	3.107e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,2IN8A@201174|Actinobacteria,4DV0I@85009|Propionibacteriales	201174|Actinobacteria	K	AefR-like transcriptional repressor, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
SRR25158390_k127_3288826_27	33898.JRHJ01000025_gene6626	1.174e-45	178.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_3288826_19	479435.Kfla_5242	1.797e-66	239.0	COG1511@1|root,COG1511@2|Bacteria,2HEUW@201174|Actinobacteria,4DQY3@85009|Propionibacteriales	201174|Actinobacteria	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3288826_28	390989.JOEG01000023_gene5741	7.505e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,4DDXG@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_3288826_24	1120950.KB892761_gene5828	3.804e-56	203.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4DR71@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158390_k127_3288826_2	414996.IL38_11135	2.627e-233	731.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,409NH@622450|Actinopolysporales	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,TspO_MBR
SRR25158390_k127_3288826_25	1237500.ANBA01000007_gene2922	8.756e-56	207.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4EI7R@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_3288826_4	1123065.ATWL01000003_gene659	5.516e-168	540.0	COG2270@1|root,COG2270@2|Bacteria,2I6N9@201174|Actinobacteria	201174|Actinobacteria	S	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158390_k127_3288826_0	479435.Kfla_6670	0.0	1194.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DN9Q@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_3288826_12	1298880.AUEV01000018_gene317	1.157e-115	376.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158390_k127_3288826_29	1298863.AUEP01000010_gene4436	3.888e-29	119.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158390_k127_3288826_11	1123065.ATWL01000003_gene601	8.011e-134	433.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158390_k127_3288826_10	1211815.CBYP010000045_gene794	8.252e-138	450.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4ESB6@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_3288826_6	526225.Gobs_4376	4.494e-156	501.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4ES1F@85013|Frankiales	201174|Actinobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158390_k127_3288826_20	58123.JOFJ01000011_gene4700	4.556e-62	218.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4EJ5I@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR25158390_k127_3288826_21	1463934.JOCF01000030_gene4935	2.145e-61	218.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_3288826_16	1449976.KALB_3491	9.916e-84	284.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria,4E2WN@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158390_k127_3288826_9	446471.Xcel_1852	1.814e-139	449.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria	201174|Actinobacteria	V	abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3288826_18	1463856.JOHY01000002_gene1322	3.465e-70	248.0	COG1277@1|root,COG1277@2|Bacteria,2GKKP@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158390_k127_3288826_7	446471.Xcel_1854	1.254e-154	492.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3288826_17	446471.Xcel_1855	1.09e-73	259.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158390_k127_3288826_30	1121272.KB903255_gene5724	4.221e-19	94.0	2B14D@1|root,2ZPR4@2|Bacteria,2GW4V@201174|Actinobacteria,4DGBG@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3288826_8	1003195.SCAT_3056	3.504e-149	479.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria	201174|Actinobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158390_k127_3288826_15	1120950.KB892812_gene7002	3.037e-85	289.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,4DPPQ@85009|Propionibacteriales	201174|Actinobacteria	P	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
SRR25158390_k127_3309753_3	1120950.KB892747_gene3745	1.901e-44	164.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4DNDW@85009|Propionibacteriales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158390_k127_3309753_1	1048339.KB913029_gene3528	1.166e-136	447.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4ES0W@85013|Frankiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158390_k127_3309753_0	58123.JOFJ01000009_gene964	9.426e-233	734.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4EG8P@85012|Streptosporangiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
SRR25158390_k127_3309753_2	1463920.JOGB01000012_gene6528	1.201e-73	252.0	COG1670@1|root,COG1670@2|Bacteria,2IKXU@201174|Actinobacteria	201174|Actinobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158390_k127_3316484_4	665577.JH993790_gene2124	3.716e-102	337.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158390_k127_3316484_1	1122182.KB903837_gene3735	2.58e-169	537.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DAHS@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158390_k127_3316484_2	1961.JOAK01000022_gene6985	8.589e-157	520.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158390_k127_3316484_3	1206726.BAFV01000118_gene5813	1.252e-117	389.0	COG0500@1|root,COG0500@2|Bacteria,2I3GX@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_3316484_0	1121946.AUAX01000026_gene6225	5.262e-179	601.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DAX8@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,GerE,Guanylate_cyc,Trans_reg_C
SRR25158390_k127_3316484_8	106370.Francci3_4280	9.607e-06	47.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4ERDW@85013|Frankiales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_3316484_7	134676.ACPL_3928	3.754e-40	164.0	COG1051@1|root,COG1051@2|Bacteria,2INBQ@201174|Actinobacteria,4DJW5@85008|Micromonosporales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_3316484_6	266940.Krad_0454	3.996e-56	212.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_3316484_5	479432.Sros_0463	1.815e-75	256.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4EGQR@85012|Streptosporangiales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158390_k127_3319358_6	1120950.KB892708_gene4431	1.435e-80	270.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4DPF1@85009|Propionibacteriales	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158390_k127_3319358_10	479431.Namu_1682	6.798e-36	151.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4ET6I@85013|Frankiales	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbB	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158390_k127_3319358_1	479435.Kfla_5101	3.23e-146	471.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria,4DU17@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158390_k127_3319358_4	479435.Kfla_5100	3.347e-109	372.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4DNBD@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158390_k127_3319358_2	1120950.KB892708_gene4435	3.81e-116	391.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4DP7N@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158390_k127_3319358_11	66874.JOFS01000030_gene8066	2.003e-13	73.0	COG1826@1|root,COG1826@2|Bacteria,2GQQX@201174|Actinobacteria	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158390_k127_3319358_8	1120950.KB892708_gene4438	4.796e-60	218.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4DQFM@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158390_k127_3319358_5	196162.Noca_2655	2.656e-105	349.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4DPPK@85009|Propionibacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRR25158390_k127_3319358_0	44060.JODL01000006_gene1382	0.0	1185.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158390_k127_3319358_9	1121272.KB903283_gene5090	7.114e-52	188.0	COG1595@1|root,COG1595@2|Bacteria,2GP2X@201174|Actinobacteria,4DM4T@85008|Micromonosporales	201174|Actinobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_3319358_3	1048339.KB913029_gene4175	6.328e-114	375.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4ERMG@85013|Frankiales	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158390_k127_3319358_7	1463879.JOHP01000023_gene3941	5.128e-68	234.0	COG1522@1|root,COG1522@2|Bacteria,2IFSQ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_3338617_9	471853.Bcav_2555	6.005e-37	143.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria	201174|Actinobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158390_k127_3338617_3	471853.Bcav_2554	5.513e-150	497.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158390_k127_3338617_6	1156844.KB891831_gene4505	3.658e-110	377.0	COG3833@1|root,COG3833@2|Bacteria,2I4A9@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_3338617_4	1452536.JARE01000040_gene2299	1.616e-117	388.0	COG1175@1|root,COG1175@2|Bacteria,2GNCE@201174|Actinobacteria,4FKXC@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_3338617_2	471853.Bcav_2551	4.109e-175	561.0	COG1653@1|root,COG1653@2|Bacteria,2I3WZ@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_3338617_1	1298863.AUEP01000015_gene1766	1.698e-246	773.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4DNVW@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_3338617_0	33876.JNXY01000016_gene6911	1.716e-301	935.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4D98S@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the TPP enzyme family	iolD	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_3338617_7	28042.GU90_14715	2.09e-107	356.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria,4DY8G@85010|Pseudonocardiales	201174|Actinobacteria	G	KduI/IolB family	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158390_k127_3338617_5	2074.JNYD01000024_gene2874	6.403e-111	366.0	COG1830@1|root,COG1830@2|Bacteria,2GKTN@201174|Actinobacteria,4DYYW@85010|Pseudonocardiales	201174|Actinobacteria	G	deoxyribose-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3338617_8	1123023.JIAI01000021_gene2368	2.303e-105	347.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,4E0W5@85010|Pseudonocardiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158390_k127_3341271_2	999141.GME_09134	3.548e-160	516.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XI75@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_3341271_11	1304865.JAGF01000001_gene388	2.097e-45	168.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4F2NC@85016|Cellulomonadaceae	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158390_k127_3341271_4	367299.JOEE01000002_gene2389	2.283e-154	500.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4FFEF@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158390_k127_3341271_1	35754.JNYJ01000013_gene1069	2.017e-171	546.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DA2N@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158390_k127_3341271_0	110319.CF8_3600	6.187e-182	576.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4DNN1@85009|Propionibacteriales	201174|Actinobacteria	C	dehydrogenase, E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158390_k127_3341271_9	471852.Tcur_3868	1.846e-69	244.0	COG1946@1|root,COG1946@2|Bacteria,2GMZB@201174|Actinobacteria,4EG4Z@85012|Streptosporangiales	201174|Actinobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158390_k127_3341271_10	1463861.JNXE01000002_gene6547	3.145e-63	234.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,SNAP,TPR_12,TPR_16
SRR25158390_k127_3341271_3	1906.SFRA_12780	1.073e-157	504.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria	201174|Actinobacteria	E	May catalyze the transamination reaction in phenylalanine biosynthesis	pat	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_3341271_13	649831.L083_0438	1.115e-35	142.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria,4DF4S@85008|Micromonosporales	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158390_k127_3341271_14	479433.Caci_8846	2.631e-18	93.0	2EV1Z@1|root,33NH1@2|Bacteria,2GZIA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3341271_12	1229203.KI301992_gene2777	1.627e-44	166.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,3UWUB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Low molecular weight phosphatase family	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158390_k127_3341271_6	585531.HMPREF0063_12738	2.357e-96	322.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4DN5P@85009|Propionibacteriales	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158390_k127_3341271_5	1463821.JOGR01000001_gene1504	3.522e-129	420.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4EZ5G@85014|Glycomycetales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3341271_7	1121926.AXWO01000010_gene3164	2.87e-80	275.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158390_k127_3341271_8	479435.Kfla_6410	1.92e-70	241.0	2DC18@1|root,2ZCCT@2|Bacteria,2IBBW@201174|Actinobacteria,4DQ74@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158390_k127_334578_1	187303.BN69_1730	3.131e-53	205.0	2ECN6@1|root,336K2@2|Bacteria,1NVTD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_334578_0	1379270.AUXF01000001_gene2513	1.207e-247	776.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	2|Bacteria	J	Amidase	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158390_k127_334578_2	525904.Tter_1985	2.362e-31	126.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158390_k127_3349527_0	710696.Intca_2714	8.357e-269	841.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4FEA5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR25158390_k127_3353270_0	28444.JODQ01000001_gene2245	2.654e-107	353.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria,4EI1I@85012|Streptosporangiales	201174|Actinobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158390_k127_3353270_1	1343740.M271_35790	2.382e-96	323.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158390_k127_3353270_2	397278.JOJN01000001_gene2592	9.178e-17	84.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DPC3@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_335630_6	1120948.KB903224_gene351	5.78e-07	54.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4E7V7@85010|Pseudonocardiales	201174|Actinobacteria	CG	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158390_k127_335630_1	1122622.ATWJ01000009_gene3369	1.52e-85	286.0	COG0662@1|root,COG0662@2|Bacteria,2IMPE@201174|Actinobacteria,4FGSG@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_335630_0	1206735.BAGG01000266_gene7062	6.022e-148	479.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4FZRT@85025|Nocardiaceae	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158390_k127_335630_7	1080067.BAZH01000035_gene2174	0.0003798	44.0	28VP7@1|root,2ZHR6@2|Bacteria,1P8M3@1224|Proteobacteria,1SVC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_335630_4	452652.KSE_45900	4.922e-16	88.0	2ETNC@1|root,33M63@2|Bacteria,2GKI3@201174|Actinobacteria,2M2MU@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_335630_2	1463858.JOHR01000012_gene2369	9.013e-70	249.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria	201174|Actinobacteria	J	N-acetyltransferase	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158390_k127_335630_3	67373.JOBF01000039_gene3688	1.576e-66	229.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158390_k127_335630_5	1449353.JQMQ01000005_gene2633	7.071e-15	76.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,2NGG5@228398|Streptacidiphilus	201174|Actinobacteria	H	MoeA N-terminal region (domain I and II)	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158390_k127_336244_2	649831.L083_7322	1.044e-27	129.0	2CHM7@1|root,2ZV0T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_336244_1	497964.CfE428DRAFT_0093	7.699e-30	134.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_336244_3	987059.RBXJA2T_05728	3.503e-15	87.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,1KKSH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158390_k127_336244_0	1510531.JQJJ01000008_gene4006	1.697e-43	172.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,2TXPS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_3363990_10	1089550.ATTH01000001_gene1987	4.33e-23	107.0	COG2866@1|root,COG2931@1|root,COG3291@1|root,COG2866@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,4NKIR@976|Bacteroidetes	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
SRR25158390_k127_3363990_6	1120950.KB892707_gene4657	3.164e-63	223.0	COG1503@1|root,COG1503@2|Bacteria,2IFQH@201174|Actinobacteria,4DQHN@85009|Propionibacteriales	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3363990_7	1206741.BAFX01000010_gene6848	1.29e-46	178.0	COG0491@1|root,COG0491@2|Bacteria,2I8XA@201174|Actinobacteria,4G5B9@85025|Nocardiaceae	201174|Actinobacteria	S	Protein involved in hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3363990_9	1463825.JNXC01000008_gene1357	7.75e-35	138.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_3363990_5	443218.AS9A_3074	4.748e-64	232.0	COG5340@1|root,COG5340@2|Bacteria,2H6VP@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_3363990_0	1120950.KB892764_gene5640	0.0	1993.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4DNQX@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158390_k127_3363990_2	1122609.AUGT01000006_gene1438	1.327e-127	412.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4DN3M@85009|Propionibacteriales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158390_k127_3363990_8	1120950.KB892764_gene5639	1.221e-37	148.0	COG3832@1|root,COG3832@2|Bacteria,2GS2W@201174|Actinobacteria,4DSAG@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
SRR25158390_k127_3363990_1	397278.JOJN01000007_gene3210	5.739e-262	816.0	COG1012@1|root,COG1012@2|Bacteria,2GJZE@201174|Actinobacteria,4DNWD@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_3363990_4	479433.Caci_7582	8.936e-86	293.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_3363990_3	1120950.KB892764_gene5608	2.749e-115	388.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4DQ9Q@85009|Propionibacteriales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158390_k127_3385072_2	1122138.AQUZ01000022_gene8672	1.094e-30	128.0	COG3064@1|root,COG3064@2|Bacteria,2HZGQ@201174|Actinobacteria,4DSRK@85009|Propionibacteriales	201174|Actinobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3385072_0	1122138.AQUZ01000016_gene285	1.293e-131	437.0	COG1222@1|root,COG1222@2|Bacteria,2IA0X@201174|Actinobacteria	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158390_k127_3385072_1	1306174.JODP01000018_gene4385	2.281e-85	289.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158390_k127_3386238_0	263358.VAB18032_13720	0.0	1272.0	COG0188@1|root,COG1372@1|root,COG0188@2|Bacteria,COG1372@2|Bacteria,2GJ2Q@201174|Actinobacteria,4D8V9@85008|Micromonosporales	201174|Actinobacteria	L	Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158390_k127_3386238_14	1120950.KB892739_gene3929	8.624e-47	174.0	29PQU@1|root,30AP1@2|Bacteria,2IFHX@201174|Actinobacteria,4DSGB@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
SRR25158390_k127_3386238_1	1120950.KB892768_gene5311	0.0	1121.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DN4A@85009|Propionibacteriales	201174|Actinobacteria	CK	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_3386238_12	1907.SGLAU_25185	1.126e-64	226.0	29850@1|root,2ZVAX@2|Bacteria,2GKR1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3386238_6	1120950.KB892748_gene3186	4.402e-120	404.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4DNS7@85009|Propionibacteriales	201174|Actinobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158390_k127_3386238_16	1122138.AQUZ01000016_gene273	6.599e-45	177.0	28PUQ@1|root,31INW@2|Bacteria,2I30V@201174|Actinobacteria,4DWFX@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3071
SRR25158390_k127_3386238_11	1122611.KB903954_gene5599	3.41e-77	273.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4EHWD@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_3386238_3	397278.JOJN01000014_gene3564	1.547e-148	482.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,4DNBP@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158390_k127_3386238_10	570268.ANBB01000037_gene2822	1.05e-80	287.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4EG2I@85012|Streptosporangiales	201174|Actinobacteria	G	Inositol monophosphatase family	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158390_k127_3386238_15	1120950.KB892748_gene3209	1.432e-45	166.0	2ATJW@1|root,31J3Z@2|Bacteria,2IKN0@201174|Actinobacteria,4DWJ1@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
SRR25158390_k127_3386238_19	479435.Kfla_3768	4.028e-33	134.0	2E4C2@1|root,32Z7M@2|Bacteria,2IFS5@201174|Actinobacteria,4DRWV@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3093)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3093
SRR25158390_k127_3386238_13	1306406.ASHX01000001_gene118	1.557e-63	221.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158390_k127_3386238_18	479435.Kfla_3765	1.86e-40	158.0	28J4D@1|root,2Z90C@2|Bacteria,2GJYC@201174|Actinobacteria,4DRF5@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
SRR25158390_k127_3386238_20	436229.JOEH01000019_gene6597	3.485e-32	129.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,2NIEC@228398|Streptacidiphilus	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3386238_17	479435.Kfla_3763	1.374e-43	171.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4DQXN@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
SRR25158390_k127_3386238_8	479435.Kfla_3762	1.066e-100	340.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DN0P@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158390_k127_3386238_9	1463861.JNXE01000024_gene7171	5.066e-95	316.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158390_k127_3386238_2	1206744.BAGL01000128_gene6756	5.763e-192	620.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4FZU5@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158390_k127_3386238_5	1385519.N801_01285	1.84e-137	448.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4FF3N@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158390_k127_3386238_4	471853.Bcav_0109	5.607e-144	462.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_3386238_7	994479.GL877878_gene1294	9.232e-119	384.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DY9U@85010|Pseudonocardiales	201174|Actinobacteria	C	aconitate hydratase	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158390_k127_3392643_0	500153.JOEK01000016_gene3419	2.397e-151	485.0	COG1649@1|root,COG1649@2|Bacteria,2GKNP@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,GHL10
SRR25158390_k127_3392643_2	1123023.JIAI01000001_gene6508	6.207e-74	256.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4E1DZ@85010|Pseudonocardiales	201174|Actinobacteria	K	GntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158390_k127_3392643_5	1123023.JIAI01000001_gene6507	1.375e-45	180.0	COG2971@1|root,COG2971@2|Bacteria,2HURV@201174|Actinobacteria,4E7XW@85010|Pseudonocardiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158390_k127_3392643_1	1122622.ATWJ01000014_gene435	5.618e-92	318.0	COG1653@1|root,COG1653@2|Bacteria,2GNYN@201174|Actinobacteria,4FHIF@85021|Intrasporangiaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_3392643_3	28444.JODQ01000002_gene4640	2.415e-71	253.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_3392643_4	28444.JODQ01000002_gene4641	2.545e-66	246.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4EHIK@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158390_k127_3392643_6	688269.Theth_0468	3.583e-06	49.0	COG1874@1|root,COG1874@2|Bacteria,2GDXZ@200918|Thermotogae	200918|Thermotogae	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3393392_7	1313172.YM304_00980	2.607e-105	357.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRR25158390_k127_3393392_0	512565.AMIS_63020	1.813e-154	502.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DA8Q@85008|Micromonosporales	201174|Actinobacteria	F	adenosine deaminase	add2	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158390_k127_3393392_6	649831.L083_1169	8.033e-113	377.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4DAPD@85008|Micromonosporales	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_3393392_1	477641.MODMU_1850	1.475e-135	444.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4EUKK@85013|Frankiales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_3393392_15	397278.JOJN01000002_gene274	2.946e-24	106.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4DS40@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158390_k127_3393392_5	443255.SCLAV_3096	2.694e-116	382.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3393392_13	1348663.KCH_38880	4.083e-54	203.0	COG0842@1|root,COG0842@2|Bacteria,2GMYB@201174|Actinobacteria,2M31H@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_3393392_9	526225.Gobs_4837	2.148e-71	256.0	COG4585@1|root,COG4585@2|Bacteria,2GSZK@201174|Actinobacteria,4EVAN@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158390_k127_3393392_8	222534.KB893757_gene4198	8.877e-91	302.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria,4EUE4@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158390_k127_3393392_4	405948.SACE_5209	2.704e-120	395.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4DYF2@85010|Pseudonocardiales	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158390_k127_3393392_14	1206726.BAFV01000126_gene6728	5.335e-43	161.0	COG4319@1|root,COG4319@2|Bacteria,2IRQ1@201174|Actinobacteria,4G96K@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158390_k127_3393392_11	1906.SFRA_10890	1.045e-64	226.0	COG0346@1|root,COG0346@2|Bacteria,2I2S6@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3393392_3	1120960.ATXG01000003_gene2107	6.305e-124	404.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4FQJ8@85023|Microbacteriaceae	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_3393392_2	1120950.KB892707_gene4822	1.704e-126	415.0	COG0715@1|root,COG0715@2|Bacteria,2GN9B@201174|Actinobacteria,4DPTI@85009|Propionibacteriales	201174|Actinobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158390_k127_3393392_10	1043493.BBLU01000014_gene1348	4.326e-68	241.0	2F548@1|root,33XRC@2|Bacteria,2H5BG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3436970_12	1033730.CAHG01000016_gene217	7.689e-11	69.0	COG0577@1|root,COG0577@2|Bacteria,2HZH5@201174|Actinobacteria,4DSSV@85009|Propionibacteriales	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3436970_11	1144275.COCOR_00429	2.434e-14	85.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158390_k127_3436970_9	1380390.JIAT01000010_gene4021	7.56e-43	169.0	COG1846@1|root,COG1846@2|Bacteria,2IMUK@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158390_k127_3436970_5	1906.SFRA_05630	3.534e-84	285.0	COG1656@1|root,COG1656@2|Bacteria,2GMQR@201174|Actinobacteria	201174|Actinobacteria	T	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
SRR25158390_k127_3436970_1	1120950.KB892812_gene7016	1.502e-185	591.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_3436970_3	1079986.JH164861_gene7150	1.712e-110	376.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_3436970_6	1463921.JODF01000014_gene6668	1.001e-64	225.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158390_k127_3436970_8	656024.FsymDg_3138	1.235e-45	170.0	COG0789@1|root,COG3585@1|root,COG0789@2|Bacteria,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158390_k127_3436970_7	1146883.BLASA_4844	5.575e-63	227.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4ESN3@85013|Frankiales	201174|Actinobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158390_k127_3436970_4	134676.ACPL_636	1.118e-96	324.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4DAIP@85008|Micromonosporales	201174|Actinobacteria	P	molybdate ABC transporter, inner membrane subunit	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR25158390_k127_3436970_2	28444.JODQ01000005_gene1545	1.214e-120	401.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4EH68@85012|Streptosporangiales	201174|Actinobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158390_k127_3436970_0	882083.SacmaDRAFT_2957	5.281e-248	776.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXK7@85010|Pseudonocardiales	201174|Actinobacteria	P	E1-E2 ATPase	copB	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158390_k127_3445050_0	1047013.AQSP01000131_gene1841	1.673e-132	467.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158390_k127_3445050_1	1267535.KB906767_gene4838	4.369e-89	314.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158390_k127_3452896_2	292459.STH2842	2.326e-190	602.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia	186801|Clostridia	E	Beta-eliminating lyase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158390_k127_3452896_0	479432.Sros_4813	5.869e-261	826.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4EM26@85012|Streptosporangiales	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_3452896_4	1123024.AUII01000034_gene2687	9.333e-33	132.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_3452896_3	1123024.AUII01000053_gene171	1.298e-172	555.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,4E8S3@85010|Pseudonocardiales	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
SRR25158390_k127_3452896_1	675635.Psed_1623	5.265e-219	691.0	COG0165@1|root,COG0165@2|Bacteria,2I9W9@201174|Actinobacteria,4EA9J@85010|Pseudonocardiales	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158390_k127_3452896_5	1123024.AUII01000034_gene2682	2.068e-11	67.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4EBSU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158390_k127_3454478_0	469371.Tbis_0417	1.389e-153	494.0	COG0683@1|root,COG0683@2|Bacteria,2HS2K@201174|Actinobacteria,4EC4C@85010|Pseudonocardiales	201174|Actinobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_3454478_1	469371.Tbis_0418	3.001e-104	344.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4EB2I@85010|Pseudonocardiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_3454478_2	469371.Tbis_0419	1.718e-21	101.0	COG0410@1|root,COG0410@2|Bacteria,2I93D@201174|Actinobacteria,4EAVV@85010|Pseudonocardiales	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3454901_6	1121272.KB903291_gene3442	3.092e-89	306.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DB65@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_3454901_4	882082.SaccyDRAFT_2540	5.946e-142	457.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJX@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_3454901_1	675635.Psed_2945	1.083e-217	694.0	COG4108@1|root,COG4108@2|Bacteria,2GKQA@201174|Actinobacteria,4DZCU@85010|Pseudonocardiales	201174|Actinobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
SRR25158390_k127_3454901_8	1476876.JOJO01000011_gene3223	5.039e-60	213.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_3454901_2	446468.Ndas_0360	4.187e-207	662.0	COG3325@1|root,COG3325@2|Bacteria,2GJGW@201174|Actinobacteria,4EHH7@85012|Streptosporangiales	201174|Actinobacteria	G	Glyco_18	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,CBM_5_12,Glyco_hydro_18,fn3
SRR25158390_k127_3454901_11	446470.Snas_2231	3.29e-24	113.0	29XFR@1|root,30J65@2|Bacteria,2HZ0U@201174|Actinobacteria,4EZ08@85014|Glycomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3454901_0	28444.JODQ01000015_gene1645	2.896e-261	839.0	COG5297@1|root,COG5297@2|Bacteria,2GMQN@201174|Actinobacteria,4EIBY@85012|Streptosporangiales	201174|Actinobacteria	G	Cellulase N-terminal ig-like domain	cel1	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_4_9,CelD_N,Glyco_hydro_9
SRR25158390_k127_3454901_10	1229780.BN381_640025	1.071e-28	131.0	COG2856@1|root,COG2856@2|Bacteria,2GPBB@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3454901_7	471852.Tcur_2637	1.572e-75	263.0	COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria,4EIKH@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_3454901_3	526225.Gobs_2962	1.749e-147	481.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158390_k127_3454901_5	397278.JOJN01000003_gene1887	1.443e-126	415.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4DNG1@85009|Propionibacteriales	201174|Actinobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158390_k127_3454901_9	479435.Kfla_0621	1.802e-35	138.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4DRSV@85009|Propionibacteriales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158390_k127_3454901_12	1032480.MLP_02340	1.172e-10	68.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DNP9@85009|Propionibacteriales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158390_k127_3457765_2	1157637.KB892116_gene107	2.775e-22	96.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria	201174|Actinobacteria	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158390_k127_3457765_0	1236902.ANAS01000009_gene2695	6.369e-81	284.0	COG2358@1|root,COG2358@2|Bacteria,2GKQJ@201174|Actinobacteria	201174|Actinobacteria	S	TRAP transporter solute receptor TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158390_k127_3457765_1	443218.AS9A_1706	1.904e-29	125.0	COG4729@1|root,COG4729@2|Bacteria,2H7QM@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1850)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1850
SRR25158390_k127_3457765_3	1236902.ANAS01000009_gene2693	4.529e-06	52.0	COG4666@1|root,COG4666@2|Bacteria,2H91Y@201174|Actinobacteria	201174|Actinobacteria	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158390_k127_3459071_3	1894.JOER01000003_gene2748	6.113e-13	76.0	COG5592@1|root,COG5592@2|Bacteria,2IJ0S@201174|Actinobacteria	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Rho_N
SRR25158390_k127_3459071_1	405948.SACE_1119	2.308e-169	542.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXU1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_3459071_0	1120950.KB892707_gene4619	4.448e-200	632.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_3459071_2	204669.Acid345_2863	3.398e-102	343.0	COG3285@1|root,COG3285@2|Bacteria,3Y637@57723|Acidobacteria,2JM9H@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158390_k127_3459206_0	479435.Kfla_4612	2.297e-198	642.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158390_k127_3459206_1	1123251.ATWM01000004_gene1763	0.0003476	48.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4FG59@85021|Intrasporangiaceae	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158390_k127_345947_6	1206726.BAFV01000070_gene4822	1.276e-69	248.0	COG0702@1|root,COG0702@2|Bacteria,2I234@201174|Actinobacteria,4FZ6J@85025|Nocardiaceae	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158390_k127_345947_10	1386089.N865_17370	2.415e-13	73.0	2EMYX@1|root,33FM2@2|Bacteria,2GZ6D@201174|Actinobacteria,4FJGG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345947_4	293826.Amet_0580	9.657e-153	497.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,36DFC@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SRR25158390_k127_345947_7	1123251.ATWM01000002_gene340	1.015e-40	156.0	2CEUC@1|root,32S0I@2|Bacteria,2HC1R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345947_5	1287276.X752_13075	9.632e-123	400.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,2U82N@28211|Alphaproteobacteria,43PGE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	SMP-30 gluconolaconase LRE-like	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158390_k127_345947_2	391037.Sare_1636	5.238e-183	595.0	COG0443@1|root,COG3266@1|root,COG0443@2|Bacteria,COG3266@2|Bacteria,2GNTE@201174|Actinobacteria,4DM1N@85008|Micromonosporales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
SRR25158390_k127_345947_1	1869.MB27_42735	3.208e-207	655.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria,4D9EK@85008|Micromonosporales	201174|Actinobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
SRR25158390_k127_345947_0	369723.Strop_1654	1.924e-210	671.0	COG0699@1|root,COG0699@2|Bacteria,2GNGP@201174|Actinobacteria,4DB0Z@85008|Micromonosporales	201174|Actinobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_345947_8	1869.MB27_42745	1.074e-32	141.0	2DBVZ@1|root,2ZBDU@2|Bacteria,2H9JZ@201174|Actinobacteria,4DK6F@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345947_3	1869.MB27_42750	5.923e-168	551.0	COG2197@1|root,COG2197@2|Bacteria,2GNUY@201174|Actinobacteria,4D8EH@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_3460288_5	446470.Snas_0657	2.363e-43	160.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria	201174|Actinobacteria	G	dehydratase	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158390_k127_3460288_1	1223545.GS4_03_01550	3.195e-121	404.0	COG1879@1|root,COG1879@2|Bacteria,2GKIJ@201174|Actinobacteria,4GDNI@85026|Gordoniaceae	201174|Actinobacteria	G	Periplasmic binding protein domain	iolTA	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
SRR25158390_k127_3460288_0	266940.Krad_4053	4.986e-136	441.0	COG1172@1|root,COG1172@2|Bacteria,2GM9E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	iolTB	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158390_k127_3460288_2	358823.DF19_10155	5.557e-119	404.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	iolTC	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158390_k127_3460288_3	653045.Strvi_4975	9.656e-96	324.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_3460288_4	1306174.JODP01000010_gene7008	1.122e-54	194.0	COG1082@1|root,COG1082@2|Bacteria,2GMU1@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Xylose isomerase domain protein TIM barrel	iolH	-	-	ko:K06605	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
SRR25158390_k127_3521865_15	1121926.AXWO01000002_gene1388	3.409e-29	134.0	2DKXG@1|root,30RUJ@2|Bacteria,2HZ2U@201174|Actinobacteria,4EZZY@85014|Glycomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3521865_0	1120950.KB892741_gene2716	0.0	1280.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DN2T@85009|Propionibacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158390_k127_3521865_19	1120950.KB892741_gene2715	5.244e-16	81.0	2ENN7@1|root,34996@2|Bacteria,2I1FI@201174|Actinobacteria,4DSMG@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3521865_6	1380356.JNIK01000016_gene3811	7.348e-122	396.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4ERGU@85013|Frankiales	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158390_k127_3521865_7	1120950.KB892741_gene2713	3.139e-99	329.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4DN7J@85009|Propionibacteriales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158390_k127_3521865_17	1238186.AOCN01000022_gene2720	3.689e-21	100.0	COG0333@1|root,COG0333@2|Bacteria,2HSQ4@201174|Actinobacteria,4FPTP@85023|Microbacteriaceae	201174|Actinobacteria	J	structural constituent of ribosome	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158390_k127_3521865_9	1172179.AUKV01000015_gene3332	5.807e-68	236.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria	201174|Actinobacteria	S	metal-binding, possibly nucleic acid-binding protein	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158390_k127_3521865_18	2074.JNYD01000013_gene6850	2.856e-16	85.0	COG3599@1|root,COG3599@2|Bacteria,2I2NA@201174|Actinobacteria,4DZXD@85010|Pseudonocardiales	201174|Actinobacteria	D	Cell division initiation protein	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3521865_10	656024.FsymDg_3692	8.903e-67	234.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4ESMC@85013|Frankiales	201174|Actinobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158390_k127_3521865_11	66429.JOFL01000030_gene5162	2.057e-60	228.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria	201174|Actinobacteria	L	methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158390_k127_3521865_1	235985.BBPN01000031_gene2148	4.239e-245	776.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,2NGWY@228398|Streptacidiphilus	201174|Actinobacteria	L	RecG wedge domain	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158390_k127_3521865_2	1122609.AUGT01000022_gene613	5.204e-155	506.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4DPSS@85009|Propionibacteriales	201174|Actinobacteria	S	Dak1_2	dak3	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158390_k127_3521865_14	1463864.JOGO01000010_gene3295	6.594e-32	124.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158390_k127_3521865_5	644283.Micau_1347	4.525e-126	410.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DADB@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158390_k127_3521865_13	1283283.ATXA01000002_gene2519	4.352e-36	138.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4ET4W@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_3521865_16	1246474.ANBE01000049_gene1381	1.653e-22	102.0	2CQFE@1|root,32SM3@2|Bacteria,2GRVK@201174|Actinobacteria,4EJZT@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3515)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3515
SRR25158390_k127_3521865_3	1120936.KB907216_gene3697	7.242e-144	465.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4EI19@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158390_k127_3521865_4	1120950.KB892741_gene2698	6.79e-140	457.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4DP28@85009|Propionibacteriales	201174|Actinobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158390_k127_3521865_8	1123320.KB889676_gene2895	2.157e-91	308.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158390_k127_3521865_12	1120950.KB892741_gene2696	1.598e-54	206.0	COG1920@1|root,COG1920@2|Bacteria,2HJNU@201174|Actinobacteria,4DRNC@85009|Propionibacteriales	201174|Actinobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158390_k127_3523523_7	1120950.KB892767_gene5173	7.444e-62	218.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4DR6U@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_3523523_0	1120950.KB892768_gene5346	1.649e-185	600.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DNYB@85009|Propionibacteriales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158390_k127_3523523_4	1120950.KB892768_gene5344	9.228e-90	314.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DNEM@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_3523523_2	1120950.KB892768_gene5343	7.048e-138	454.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4DP7S@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	mprB	GO:0000160,GO:0003674,GO:0003824,GO:0004721,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0040007,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_3523523_3	1120950.KB892768_gene5342	7.181e-107	349.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DP6U@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_3523523_1	1048339.KB913029_gene3833	5.054e-164	527.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4ESAZ@85013|Frankiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158390_k127_3523523_8	1122138.AQUZ01000016_gene181	3.542e-51	188.0	COG0589@1|root,COG0589@2|Bacteria,2IR3G@201174|Actinobacteria,4DRRV@85009|Propionibacteriales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3523523_6	100226.SCO4047	4.516e-70	242.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158390_k127_3523523_5	446466.Cfla_2057	9.747e-75	263.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4F127@85016|Cellulomonadaceae	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_3523727_5	526225.Gobs_3043	5.43e-48	176.0	COG0745@1|root,COG1587@1|root,COG0745@2|Bacteria,COG1587@2|Bacteria,2GKMM@201174|Actinobacteria,4ESGJ@85013|Frankiales	201174|Actinobacteria	HKT	Uroporphyrinogen III synthase HEM4	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Trans_reg_C
SRR25158390_k127_3523727_2	356851.JOAN01000015_gene2600	5.316e-125	407.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4DAIJ@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158390_k127_3523727_1	356851.JOAN01000015_gene2599	1.405e-131	426.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D8SS@85008|Micromonosporales	201174|Actinobacteria	V	resistance ABC transporter ATPase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_3523727_4	1150864.MILUP08_42361	2.334e-63	226.0	COG1309@1|root,COG1309@2|Bacteria,2GYYS@201174|Actinobacteria,4DEP4@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_3523727_7	1126627.BAWE01000002_gene553	3.662e-09	60.0	2BUZT@1|root,32QCC@2|Bacteria,1Q8TE@1224|Proteobacteria,2UYDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3523727_6	1187851.A33M_4394	1.329e-47	175.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_3523727_3	1157637.KB892093_gene6656	2.911e-80	274.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_3523727_0	1120950.KB892740_gene2531	1.465e-153	492.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4DN51@85009|Propionibacteriales	201174|Actinobacteria	M	Ami_3	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
SRR25158390_k127_3526923_3	1123234.AUKI01000008_gene998	2.116e-05	50.0	29FE7@1|root,302BX@2|Bacteria,4NMTG@976|Bacteroidetes,1I1WT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3526923_2	446468.Ndas_2678	7.152e-59	211.0	COG5592@1|root,COG5592@2|Bacteria,2HF5Y@201174|Actinobacteria,4EJFU@85012|Streptosporangiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_3526923_0	1123024.AUII01000006_gene4677	1.108e-196	620.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DXR5@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase GroES-like	fdhA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_3526923_1	1033730.CAHG01000006_gene1052	1.238e-88	298.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DN4M@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	yghA	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_3528741_8	1120949.KB903294_gene3517	2.957e-95	316.0	COG1129@1|root,COG1129@2|Bacteria,2IC7X@201174|Actinobacteria,4DH8D@85008|Micromonosporales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158390_k127_3528741_18	1089551.KE386572_gene291	2.008e-43	167.0	COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,2UDPS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_3528741_7	1267534.KB906755_gene4156	2.385e-102	346.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Z2@57723|Acidobacteria,2JMN3@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158390_k127_3528741_10	1283299.AUKG01000001_gene2492	2.233e-89	310.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4CS1G@84995|Rubrobacteria	84995|Rubrobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158390_k127_3528741_19	391037.Sare_0780	2.268e-29	128.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4DC96@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3528741_20	1123024.AUII01000013_gene416	2.473e-25	107.0	2EH65@1|root,33AY1@2|Bacteria,2I34E@201174|Actinobacteria,4EE7S@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876
SRR25158390_k127_3528741_15	1236902.ANAS01000013_gene1318	2.494e-60	223.0	COG1503@1|root,COG1503@2|Bacteria,2IJI5@201174|Actinobacteria,4EMMU@85012|Streptosporangiales	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3528741_16	1463845.JOIG01000003_gene4947	3.794e-58	215.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158390_k127_3528741_3	330084.JNYZ01000041_gene5102	5.195e-118	383.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4DYR2@85010|Pseudonocardiales	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_3528741_13	1179773.BN6_60300	7.554e-68	243.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria,4E6RW@85010|Pseudonocardiales	201174|Actinobacteria	KT	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,LMWPc
SRR25158390_k127_3528741_9	356851.JOAN01000016_gene6095	1.636e-94	314.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4D90R@85008|Micromonosporales	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158390_k127_3528741_2	469383.Cwoe_4495	3.403e-127	417.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CP9Q@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158390_k127_3528741_4	1137268.AZXF01000038_gene4055	6.457e-116	383.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4EN8Q@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_3528741_5	1137268.AZXF01000038_gene4056	4.612e-114	381.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4EN85@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_3528741_6	1137268.AZXF01000038_gene4057	1.142e-105	353.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria,4EN38@85012|Streptosporangiales	201174|Actinobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158390_k127_3528741_11	266940.Krad_0921	7.634e-80	289.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_3528741_12	561175.KB894093_gene3354	1.509e-75	258.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4EGZ9@85012|Streptosporangiales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158390_k127_3528741_1	1123024.AUII01000006_gene4654	3.022e-145	468.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4E1VE@85010|Pseudonocardiales	201174|Actinobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158390_k127_3528741_14	1127134.NOCYR_3928	1.135e-62	228.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4FVR6@85025|Nocardiaceae	201174|Actinobacteria	GL	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158390_k127_3528741_17	1120950.KB892777_gene740	2.135e-48	195.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4DQ28@85009|Propionibacteriales	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158390_k127_3528741_0	1120950.KB892777_gene739	7.223e-298	925.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4DNIH@85009|Propionibacteriales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158390_k127_3554810_1	1206739.BAGJ01000011_gene3401	5.06e-73	250.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4FUCF@85025|Nocardiaceae	201174|Actinobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158390_k127_3554810_0	1120950.KB892790_gene2083	9.524e-137	440.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4DND2@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158390_k127_355697_3	1068978.AMETH_3533	6.982e-78	269.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4E1HJ@85010|Pseudonocardiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_355697_4	1068978.AMETH_3532	3.249e-57	206.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria	201174|Actinobacteria	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158390_k127_355697_2	1122939.ATUD01000001_gene108	4.214e-108	357.0	28KEQ@1|root,30PSG@2|Bacteria,2I3BU@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4429,SHOCT
SRR25158390_k127_355697_1	28444.JODQ01000006_gene736	1.201e-110	365.0	COG3970@1|root,COG3970@2|Bacteria,2GN7V@201174|Actinobacteria,4EIVQ@85012|Streptosporangiales	201174|Actinobacteria	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158390_k127_355697_0	219305.MCAG_02550	4.727e-122	399.0	COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria,4DC78@85008|Micromonosporales	201174|Actinobacteria	S	Cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_355697_5	1312959.KI914647_gene194	1.672e-23	101.0	COG3677@1|root,COG3677@2|Bacteria,2IF2C@201174|Actinobacteria	201174|Actinobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158390_k127_355862_2	1179773.BN6_27320	6.015e-61	218.0	COG2755@1|root,COG2755@2|Bacteria,2GKSW@201174|Actinobacteria,4DZ4Q@85010|Pseudonocardiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
SRR25158390_k127_355862_4	58123.JOFJ01000012_gene5322	4.759e-28	115.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4EKF4@85012|Streptosporangiales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158390_k127_355862_3	981369.JQMJ01000004_gene2289	2.951e-54	200.0	COG1670@1|root,COG1670@2|Bacteria,2I4GW@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158390_k127_355862_0	1246445.ANAY01000012_gene30	7.827e-105	351.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4EFJ5@85012|Streptosporangiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158390_k127_355862_1	477641.MODMU_4528	4.958e-63	217.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4ES1R@85013|Frankiales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158390_k127_3585097_1	263358.VAB18032_08835	7.5e-96	321.0	COG0583@1|root,COG0583@2|Bacteria,2GJEC@201174|Actinobacteria,4D932@85008|Micromonosporales	201174|Actinobacteria	K	Chromosome replication initiation inhibitor protein	iciA	GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_3585097_0	1120950.KB892750_gene6901	1.421e-141	454.0	COG0491@1|root,COG0491@2|Bacteria,2I9IC@201174|Actinobacteria,4DT7C@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3585097_2	1123322.KB904671_gene2849	3.958e-43	158.0	COG1733@1|root,COG1733@2|Bacteria,2IJCU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_3597258_10	234621.RER_57260	1.318e-100	336.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4FYKW@85025|Nocardiaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_3597258_5	1463821.JOGR01000013_gene3300	1.026e-120	399.0	COG1718@1|root,COG1718@2|Bacteria,2GM3J@201174|Actinobacteria,4EY3G@85014|Glycomycetales	201174|Actinobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
SRR25158390_k127_3597258_13	1385520.N802_10710	4.056e-49	184.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,4FHB7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158390_k127_3597258_0	105420.BBPO01000047_gene1661	0.0	1274.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,2NGRH@228398|Streptacidiphilus	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158390_k127_3597258_14	479432.Sros_0512	7.269e-28	115.0	2BZ6B@1|root,336KR@2|Bacteria,2IQEV@201174|Actinobacteria,4EKJF@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3597258_11	1463825.JNXC01000001_gene5883	1.006e-80	276.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4E0RD@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158390_k127_3597258_7	1120950.KB892760_gene5780	2.289e-105	352.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4DR6P@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_3597258_12	1120950.KB892782_gene272	1.538e-77	263.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4DQ99@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158390_k127_3597258_9	1120950.KB892782_gene269	1.299e-100	331.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DN90@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158390_k127_3597258_2	110319.CF8_3523	3.922e-132	436.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4DRHN@85009|Propionibacteriales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_3597258_3	35754.JNYJ01000007_gene2931	9.969e-131	442.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DEZ6@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3597258_6	35754.JNYJ01000007_gene2930	1.713e-105	352.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DH4D@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3597258_1	1121272.KB903272_gene442	1.585e-277	875.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DA3R@85008|Micromonosporales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_3597258_4	35754.JNYJ01000007_gene2928	2.829e-126	408.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DDVG@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158390_k127_3597258_8	35754.JNYJ01000007_gene2927	2.417e-105	346.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D9QU@85008|Micromonosporales	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3610949_5	882083.SacmaDRAFT_2562	3.138e-22	98.0	COG4147@1|root,COG4147@2|Bacteria,2GM3H@201174|Actinobacteria,4DY0B@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158390_k127_3610949_3	743718.Isova_1036	2.003e-36	142.0	2FB67@1|root,343CH@2|Bacteria,2I76T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3610949_2	743718.Isova_1037	6.482e-41	161.0	2BBE7@1|root,324XD@2|Bacteria,2GRRW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3610949_1	743718.Isova_1038	6.293e-44	162.0	COG4327@1|root,COG4327@2|Bacteria,2IRIC@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
SRR25158390_k127_3610949_0	743718.Isova_1039	2.453e-280	869.0	COG4147@1|root,COG4147@2|Bacteria,2GJ56@201174|Actinobacteria,4F3VC@85017|Promicromonosporaceae	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158390_k127_3610949_4	1122997.AUDD01000007_gene900	3.048e-25	109.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4DRJ7@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158390_k127_3614370_1	479435.Kfla_5123	2.02e-36	139.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria,4DR7T@85009|Propionibacteriales	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
SRR25158390_k127_3614370_0	1172188.KB911820_gene2639	4.89e-115	383.0	COG0438@1|root,COG0438@2|Bacteria,2GNUU@201174|Actinobacteria,4FFUI@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
SRR25158390_k127_3614370_2	994479.GL877879_gene4662	3.969e-21	98.0	COG3393@1|root,COG3393@2|Bacteria,2IKNJ@201174|Actinobacteria,4E4HA@85010|Pseudonocardiales	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158390_k127_3628904_9	1032480.MLP_15120	5.203e-47	174.0	COG1403@1|root,COG1403@2|Bacteria,2I9AH@201174|Actinobacteria,4DMZA@85009|Propionibacteriales	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_3628904_11	1157634.KB912964_gene5625	2.976e-05	46.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria	201174|Actinobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158390_k127_3628904_0	1120950.KB892707_gene4745	1.976e-263	816.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4DNAS@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_3628904_10	1120950.KB892707_gene4746	3.726e-25	109.0	COG1714@1|root,COG1714@2|Bacteria,2IQMG@201174|Actinobacteria,4DSWX@85009|Propionibacteriales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_3628904_7	1120950.KB892707_gene4748	5.537e-65	229.0	2AUFS@1|root,31K3Y@2|Bacteria,2GIXC@201174|Actinobacteria,4DQHR@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4191
SRR25158390_k127_3628904_4	1123065.ATWL01000006_gene2251	1.077e-119	391.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria	201174|Actinobacteria	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158390_k127_3628904_3	935866.JAER01000011_gene2235	1.769e-167	531.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4DPBB@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158390_k127_3628904_5	58123.JOFJ01000001_gene3204	1.209e-85	293.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4EINN@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158390_k127_3628904_8	1380356.JNIK01000021_gene4510	5.764e-58	221.0	COG0515@1|root,COG0515@2|Bacteria,2ID99@201174|Actinobacteria,4EV2G@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_3628904_6	105420.BBPO01000076_gene4643	9.382e-82	282.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,2NG6D@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158390_k127_3628904_1	477641.MODMU_3550	4.931e-210	670.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4ERCG@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E2 component	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158390_k127_3628904_2	219305.MCAG_01314	2.349e-189	596.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4D8XG@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_3628951_4	1123065.ATWL01000007_gene3239	8.678e-66	242.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3628951_0	469371.Tbis_0422	5.686e-140	462.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4E9MB@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158390_k127_3628951_1	469371.Tbis_0421	3.67e-134	445.0	COG4177@1|root,COG4177@2|Bacteria,2GNZK@201174|Actinobacteria,4EAX9@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158390_k127_3628951_2	469371.Tbis_0420	6.272e-121	400.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4E11I@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
SRR25158390_k127_3628951_3	469371.Tbis_0419	5.614e-83	279.0	COG0410@1|root,COG0410@2|Bacteria,2I93D@201174|Actinobacteria,4EAVV@85010|Pseudonocardiales	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3644213_3	1463917.JODC01000008_gene3230	1.698e-184	584.0	COG0160@1|root,COG0160@2|Bacteria,2GJNQ@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
SRR25158390_k127_3644213_1	68260.JOAY01000019_gene1517	4.347e-246	770.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_3644213_0	28042.GU90_13845	1.034e-287	901.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4DYAF@85010|Pseudonocardiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158390_k127_3644213_2	2045.KR76_08380	3.752e-196	617.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DPQU@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3644213_8	28444.JODQ01000006_gene640	1.485e-12	72.0	2E89B@1|root,332N6@2|Bacteria,2IMU0@201174|Actinobacteria,4EKDH@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3644213_5	1120950.KB892708_gene4448	2.911e-66	228.0	COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria,4DQJS@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix ASNC type	lrp_3	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_3644213_7	1047013.AQSP01000106_gene1780	6.089e-34	135.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158390_k127_3644213_4	1150864.MILUP08_42435	8.747e-142	458.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4DC2F@85008|Micromonosporales	201174|Actinobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_3644213_6	1125971.ASJB01000064_gene6680	1.27e-51	184.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4DXYB@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_3645914_2	1133849.O3I_016400	7.846e-102	347.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4FU0V@85025|Nocardiaceae	201174|Actinobacteria	CH	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,SE
SRR25158390_k127_3645914_9	1122997.AUDD01000009_gene247	2.14e-08	55.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4DVGI@85009|Propionibacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158390_k127_3645914_6	1288079.AUKN01000017_gene12	2.825e-67	239.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158390_k127_3645914_7	479433.Caci_7257	2.916e-50	182.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158390_k127_3645914_3	469371.Tbis_2453	3.433e-97	322.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4E0CB@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158390_k127_3645914_0	106370.Francci3_1227	2.516e-171	552.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4ERK4@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
SRR25158390_k127_3645914_8	1120950.KB892747_gene3748	1.951e-43	166.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4DR63@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158390_k127_3645914_1	408672.NBCG_05095	3.243e-116	382.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DN7T@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_3645914_5	1380356.JNIK01000016_gene3839	1.619e-84	298.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4ESKB@85013|Frankiales	201174|Actinobacteria	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158390_k127_3645914_4	1906.SFRA_23900	1.131e-91	309.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria	201174|Actinobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158390_k127_3654339_0	1068980.ARVW01000001_gene858	3.772e-123	404.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8,Oxidored_FMN
SRR25158390_k127_3654339_1	1068980.ARVW01000001_gene857	9.831e-114	373.0	COG2141@1|root,COG2141@2|Bacteria,2HVKH@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3654339_2	1089544.KB912942_gene3982	2.927e-29	119.0	COG3327@1|root,COG3327@2|Bacteria,2IDVQ@201174|Actinobacteria,4E8NN@85010|Pseudonocardiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158390_k127_365815_1	1122622.ATWJ01000013_gene57	1.032e-142	467.0	COG0365@1|root,COG0365@2|Bacteria,2I9ZT@201174|Actinobacteria,4FIBR@85021|Intrasporangiaceae	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_365815_4	262316.MAP_0519c	1.543e-34	136.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,239MD@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	ddn	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_365815_3	485913.Krac_2602	6.653e-53	196.0	COG0500@1|root,COG2226@2|Bacteria,2G73U@200795|Chloroflexi	2|Bacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158390_k127_365815_2	263358.VAB18032_10835	2.495e-95	321.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4DB32@85008|Micromonosporales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158390_k127_365815_0	263358.VAB18032_10830	6e-323	1004.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,Glyco_hydro_43
SRR25158390_k127_3677304_2	1123065.ATWL01000011_gene45	5.349e-43	160.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_3677304_0	926564.KI911710_gene2814	4.063e-89	305.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4F4D0@85017|Promicromonosporaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3677304_1	28444.JODQ01000003_gene4715	3.899e-82	277.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158390_k127_3685641_18	1123023.JIAI01000002_gene5206	3.537e-60	218.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4DYZ0@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158390_k127_3685641_7	1177181.T9A_01906	6.205e-110	364.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,1XNYS@135619|Oceanospirillales	135619|Oceanospirillales	P	Polycystin cation channel	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
SRR25158390_k127_3685641_19	405948.SACE_6876	1.756e-48	177.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4E3JC@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the UPF0336 family	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158390_k127_3685641_20	1134445.AJJM01000027_gene4444	5.91e-47	174.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158390_k127_3685641_4	1120950.KB892746_gene3572	9.748e-137	448.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4DNF7@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158390_k127_3685641_2	479435.Kfla_6174	4.125e-158	506.0	COG1816@1|root,COG1816@2|Bacteria,2GKJP@201174|Actinobacteria,4DN6T@85009|Propionibacteriales	201174|Actinobacteria	F	adenosine deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158390_k127_3685641_1	1048339.KB913029_gene2726	1.927e-207	651.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4ES0T@85013|Frankiales	201174|Actinobacteria	E	aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_3685641_27	312284.A20C1_11676	5.249e-18	85.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,3UWZR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158390_k127_3685641_11	1048339.KB913029_gene2728	9.97e-90	301.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4ES8J@85013|Frankiales	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158390_k127_3685641_15	1463881.KL591014_gene741	6.336e-72	244.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158390_k127_3685641_6	1394178.AWOO02000003_gene2789	1.607e-111	365.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4EG6U@85012|Streptosporangiales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158390_k127_3685641_29	1137269.AZWL01000015_gene649	3.502e-09	68.0	2DPU0@1|root,333DA@2|Bacteria,2GNE1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LppX_LprAFG
SRR25158390_k127_3685641_12	222534.KB893723_gene621	5.887e-78	268.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EVS6@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_3685641_16	1463854.JOHT01000009_gene1905	7.317e-72	251.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158390_k127_3685641_21	1445613.JALM01000007_gene497	2.635e-37	155.0	COG1802@1|root,COG1802@2|Bacteria,2GJRM@201174|Actinobacteria,4E0DB@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_3685641_17	1206739.BAGJ01000086_gene492	1.936e-71	244.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria,4G1JJ@85025|Nocardiaceae	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_3685641_5	1298863.AUEP01000019_gene3506	7.573e-114	378.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4DNUU@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158390_k127_3685641_31	1206744.BAGL01000128_gene6904	5.617e-06	53.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	ABM
SRR25158390_k127_3685641_13	1172179.AUKV01000004_gene6436	2.472e-76	261.0	COG2128@1|root,COG2128@2|Bacteria,2H4IP@201174|Actinobacteria	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_3685641_24	1206739.BAGJ01000071_gene6472	4.056e-33	131.0	COG1733@1|root,COG1733@2|Bacteria,2GSST@201174|Actinobacteria,4G4DR@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_3685641_23	1380393.JHVP01000001_gene2619	5.322e-35	141.0	COG1418@1|root,COG1418@2|Bacteria,2GJPC@201174|Actinobacteria,4EVNP@85013|Frankiales	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158390_k127_3685641_26	1348663.KCH_34020	2.022e-22	102.0	2EGDD@1|root,33A58@2|Bacteria,2GR3X@201174|Actinobacteria,2M3K6@2063|Kitasatospora	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR25158390_k127_3685641_9	446462.Amir_0405	1.126e-98	334.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_3685641_3	1068978.AMETH_5240	6.053e-150	481.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4E9T9@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_3685641_0	644283.Micau_3465	2.767e-239	749.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4D98C@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158390_k127_3685641_8	1146883.BLASA_0136	6.333e-101	340.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4EUSJ@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3685641_30	469371.Tbis_0277	1.694e-07	56.0	2DH0N@1|root,2ZXZ9@2|Bacteria,2GUM5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4229
SRR25158390_k127_3685641_28	446466.Cfla_2943	1.226e-09	64.0	COG3905@1|root,COG3905@2|Bacteria,2GWKG@201174|Actinobacteria	201174|Actinobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158390_k127_3685641_25	446466.Cfla_2944	2.692e-26	111.0	COG1848@1|root,COG1848@2|Bacteria,2GPX7@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158390_k127_3685641_22	1068978.AMETH_5685	9.509e-36	141.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_3685641_10	446469.Sked_07260	1.284e-90	317.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158390_k127_3685641_14	1120950.KB892779_gene993	1.041e-74	258.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4DP67@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_3689121_11	882083.SacmaDRAFT_2508	1.996e-08	57.0	COG4447@1|root,COG4447@2|Bacteria,2GN53@201174|Actinobacteria,4E3VF@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158390_k127_3689121_6	994479.GL877880_gene3837	6.593e-68	239.0	COG0030@1|root,COG0030@2|Bacteria,2H1TK@201174|Actinobacteria,4DXHF@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermE	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
SRR25158390_k127_3689121_5	1449346.JQMO01000003_gene5571	4.734e-82	282.0	COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria,2M116@2063|Kitasatospora	201174|Actinobacteria	Q	Methyltransferase domain	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_3689121_1	526225.Gobs_2962	1.613e-155	508.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158390_k127_3689121_2	397278.JOJN01000003_gene1887	1.306e-138	450.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4DNG1@85009|Propionibacteriales	201174|Actinobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158390_k127_3689121_9	1504319.GM45_2875	2.449e-35	137.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria	201174|Actinobacteria	C	NADP transhydrogenase	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158390_k127_3689121_0	1504319.GM45_2880	1.172e-166	536.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,3UX38@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NAD(P) transhydrogenase beta subunit	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158390_k127_3689121_3	469371.Tbis_3539	4.332e-107	349.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4DZ16@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158390_k127_3689121_12	105420.BBPO01000033_gene3764	2.482e-07	55.0	28SPD@1|root,2ZEZI@2|Bacteria,2GQJR@201174|Actinobacteria,2NJS5@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3689121_8	1120950.KB892742_gene3016	2.083e-46	173.0	2BM8T@1|root,32FSI@2|Bacteria,2IG06@201174|Actinobacteria,4DR8K@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA adenosine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3689121_7	1120950.KB892742_gene3018	5.162e-67	235.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158390_k127_3689121_13	1101189.AQUO01000002_gene728	0.0001219	48.0	COG1961@1|root,COG1961@2|Bacteria,1PFVE@1224|Proteobacteria,2V7HD@28211|Alphaproteobacteria,2PYM2@265|Paracoccus	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Zn_ribbon_recom
SRR25158390_k127_3689121_10	457429.ABJI02000741_gene338	2.808e-11	64.0	COG0654@1|root,COG2072@1|root,COG0654@2|Bacteria,COG2072@2|Bacteria,2GK95@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	arsO	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158390_k127_3689121_4	324602.Caur_1046	1.435e-86	321.0	COG2114@1|root,COG3899@1|root,COG4166@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG4166@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158390_k127_3701432_1	1229780.BN381_490004	4.677e-74	262.0	COG3153@1|root,COG3153@2|Bacteria,2I8ZE@201174|Actinobacteria	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SRR25158390_k127_3701432_0	1385519.N801_07500	2.278e-98	334.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4FG91@85021|Intrasporangiaceae	201174|Actinobacteria	M	Lipopolysaccharide biosynthesis protein	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_3701432_2	1121372.AULK01000003_gene310	1.159e-31	131.0	COG0394@1|root,COG0394@2|Bacteria,2ISIM@201174|Actinobacteria,4FPY8@85023|Microbacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
SRR25158390_k127_3701432_3	471853.Bcav_0456	2.48e-23	107.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR25158390_k127_3746519_6	935839.JAGJ01000010_gene376	3.186e-62	217.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4F3G7@85017|Promicromonosporaceae	201174|Actinobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158390_k127_3746519_7	446471.Xcel_0998	2.504e-56	205.0	COG0295@1|root,COG0295@2|Bacteria,2IHP7@201174|Actinobacteria,4F4SD@85017|Promicromonosporaceae	201174|Actinobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158390_k127_3746519_0	1386089.N865_02895	9.372e-208	653.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4FETB@85021|Intrasporangiaceae	201174|Actinobacteria	F	pyrimidine-nucleoside phosphorylase	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158390_k127_3746519_2	367299.JOEE01000004_gene942	7.216e-139	460.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4FE56@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptide ABC transporter substrate-binding protein	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158390_k127_3746519_3	446462.Amir_0677	2.528e-120	393.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DZ5D@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158390_k127_3746519_5	1048339.KB913029_gene1646	7.214e-111	367.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4EUHI@85013|Frankiales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_3746519_1	1123320.KB889719_gene7334	2.447e-150	494.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_3746519_4	2045.KR76_20790	2.836e-113	389.0	COG2120@1|root,COG2120@2|Bacteria,2GKUM@201174|Actinobacteria,4DN6S@85009|Propionibacteriales	201174|Actinobacteria	S	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway	mshB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	3.5.1.103	ko:K15525	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158390_k127_3747864_3	314278.NB231_14046	2.195e-86	291.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X2Q3@135613|Chromatiales	135613|Chromatiales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_3747864_4	1236902.ANAS01000034_gene1009	3.553e-37	156.0	COG3266@1|root,COG3266@2|Bacteria,2I39E@201174|Actinobacteria,4EHMF@85012|Streptosporangiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3747864_2	479435.Kfla_1276	8.994e-93	309.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4DPAW@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158390_k127_3747864_0	1120950.KB892760_gene5724	3.019e-237	744.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4DP1R@85009|Propionibacteriales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158390_k127_3747864_1	1089545.KB913037_gene3460	4.357e-171	560.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4E1FM@85010|Pseudonocardiales	201174|Actinobacteria	L	SNF2 family N-terminal domain	helZ	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
SRR25158390_k127_3753061_0	555079.Toce_2076	3.488e-38	148.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_3753061_1	1122138.AQUZ01000046_gene332	3.786e-24	113.0	2B7J7@1|root,320PT@2|Bacteria,2H4GG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3757140_2	861299.J421_4186	3.09e-19	91.0	COG0580@1|root,COG0580@2|Bacteria,1ZV9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158390_k127_3757140_0	47716.JOFH01000002_gene6184	2.535e-236	744.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158390_k127_3757140_1	1206739.BAGJ01000086_gene472	4.873e-150	500.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FW63@85025|Nocardiaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
SRR25158390_k127_3763923_9	40571.JOEA01000006_gene4403	1.305e-13	71.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DY02@85010|Pseudonocardiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158390_k127_3763923_3	1120950.KB892804_gene1468	2.87e-131	429.0	COG2222@1|root,COG2222@2|Bacteria,2I433@201174|Actinobacteria,4DR3Q@85009|Propionibacteriales	201174|Actinobacteria	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158390_k127_3763923_4	1120950.KB892804_gene1467	1.022e-82	283.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4DR9U@85009|Propionibacteriales	201174|Actinobacteria	K	UTRA	hutC	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158390_k127_3763923_7	1463934.JOCF01000037_gene2140	9.594e-23	99.0	COG1920@1|root,COG1920@2|Bacteria,2GQPF@201174|Actinobacteria	201174|Actinobacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3763923_1	469371.Tbis_0178	7.048e-176	556.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4DZK9@85010|Pseudonocardiales	201174|Actinobacteria	G	fructose-bisphosphate aldolase, class II, yeast E. coli subtype	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158390_k127_3763923_0	585531.HMPREF0063_12819	2.063e-222	698.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4DNMU@85009|Propionibacteriales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158390_k127_3763923_5	479435.Kfla_0243	2.106e-58	218.0	COG3103@1|root,COG3103@2|Bacteria,2I3RJ@201174|Actinobacteria,4DR7V@85009|Propionibacteriales	201174|Actinobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158390_k127_3763923_2	103733.JNYO01000012_gene2639	4.861e-159	507.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DXA1@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158390_k127_3763923_8	356851.JOAN01000013_gene5713	1.225e-14	81.0	COG1595@1|root,COG1595@2|Bacteria,2IP48@201174|Actinobacteria,4DE61@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_3763923_6	479432.Sros_7947	1.429e-40	154.0	COG0789@1|root,COG0789@2|Bacteria,2IFX0@201174|Actinobacteria,4EJH1@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_3763923_10	661478.OP10G_4549	1.038e-09	60.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158390_k127_3765396_5	1077974.GOEFS_131_00020	7.796e-09	57.0	COG4636@1|root,COG4636@2|Bacteria,2I1A5@201174|Actinobacteria,4GGPD@85026|Gordoniaceae	201174|Actinobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158390_k127_3765396_1	1122611.KB903989_gene7214	2.904e-103	351.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4EFGM@85012|Streptosporangiales	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158390_k127_3765396_0	1003195.SCAT_2043	2.117e-141	455.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158390_k127_3765396_2	196162.Noca_1411	2.151e-40	152.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4DRN7@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_3765396_3	1463909.KL585973_gene86	4.985e-20	94.0	COG1487@1|root,COG1487@2|Bacteria,2ISD3@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_3765396_4	2002.JOEQ01000004_gene3025	2.114e-17	91.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4EHA5@85012|Streptosporangiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158390_k127_377060_1	518766.Rmar_1863	1.509e-66	243.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1FIRJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
SRR25158390_k127_377060_0	861299.J421_1832	3.369e-276	882.0	COG1629@1|root,COG4771@2|Bacteria,1ZUKQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158390_k127_3778176_2	1150864.MILUP08_45671	4.7e-58	206.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4DDFU@85008|Micromonosporales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158390_k127_3778176_3	590998.Celf_1490	1.307e-08	60.0	2EHND@1|root,33BE5@2|Bacteria,2I1BA@201174|Actinobacteria,4F1IZ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4233)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4233
SRR25158390_k127_3778176_1	1123320.KB889629_gene7885	2.055e-164	528.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria	201174|Actinobacteria	H	Folylpolyglutamate synthase	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_3778176_0	1048339.KB913029_gene4867	0.0	1389.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4ERSS@85013|Frankiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158390_k127_3779454_7	1289387.AUKW01000011_gene846	1.449e-58	204.0	arCOG06277@1|root,330C9@2|Bacteria,2IJX3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3779454_0	1123320.KB889603_gene8579	9.219e-215	679.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
SRR25158390_k127_3779454_2	2074.JNYD01000002_gene5635	3.654e-88	300.0	COG0715@1|root,COG0715@2|Bacteria,2IEVS@201174|Actinobacteria,4E6SW@85010|Pseudonocardiales	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRR25158390_k127_3779454_5	1123023.JIAI01000012_gene9106	6.811e-64	229.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_3779454_4	1463820.JOGW01000014_gene561	1.311e-73	254.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_3779454_1	1246995.AFR_16250	1.323e-96	343.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I8X1@201174|Actinobacteria,4DH0K@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HisKA_3
SRR25158390_k127_3779454_3	67373.JOBF01000024_gene6917	3.84e-88	304.0	COG1482@1|root,COG1482@2|Bacteria,2GJXC@201174|Actinobacteria	201174|Actinobacteria	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SRR25158390_k127_3779454_6	1227497.C491_19009	2.446e-62	224.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea,2Y385@28890|Euryarchaeota,23ZCI@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_3779454_8	463191.SSEG_10348	8e-34	135.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3783181_2	1968.JOEV01000021_gene5868	1.587e-07	55.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158390_k127_3783181_3	1380347.JNII01000006_gene1317	3.882e-07	60.0	2DP6P@1|root,330SA@2|Bacteria,2H045@201174|Actinobacteria	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
SRR25158390_k127_3783181_0	397278.JOJN01000006_gene1053	4.458e-27	113.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4DRWZ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158390_k127_3783181_1	471852.Tcur_1967	4.761e-27	115.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4EFZD@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158390_k127_3790173_3	452863.Achl_2634	7.365e-08	56.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158390_k127_3790173_1	1464048.JNZS01000034_gene2640	1.269e-59	214.0	COG2197@1|root,COG2197@2|Bacteria,2IBDE@201174|Actinobacteria,4D9GH@85008|Micromonosporales	201174|Actinobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_3790173_0	110319.CF8_2742	3.19e-102	353.0	COG4585@1|root,COG4585@2|Bacteria,2IAQN@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA_3
SRR25158390_k127_3790173_2	110319.CF8_2741	1.919e-49	179.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4DR34@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_3795975_1	1210046.B277_12035	3.908e-201	631.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4FF0W@85021|Intrasporangiaceae	201174|Actinobacteria	J	in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158390_k127_3795975_4	471852.Tcur_2849	1.877e-79	289.0	COG3568@1|root,COG3568@2|Bacteria,2GP1E@201174|Actinobacteria	201174|Actinobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_3795975_2	1089544.KB912942_gene3126	3.584e-122	407.0	COG0237@1|root,COG2320@1|root,COG0237@2|Bacteria,COG2320@2|Bacteria,2GN96@201174|Actinobacteria,4DYSR@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158390_k127_3795975_6	1121946.AUAX01000008_gene7235	4.097e-09	66.0	COG3667@1|root,COG3667@2|Bacteria,2IHUC@201174|Actinobacteria,4DDBI@85008|Micromonosporales	201174|Actinobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3795975_3	103733.JNYO01000019_gene2134	1.48e-82	280.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria,4E32Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158390_k127_3795975_5	1230476.C207_05768	1.486e-63	222.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2U98I@28211|Alphaproteobacteria,3JUN3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158390_k127_3795975_0	479435.Kfla_3112	1.08e-222	696.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4DN5W@85009|Propionibacteriales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158390_k127_3801900_1	1223523.H340_26931	6.071e-68	237.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3801900_0	457429.ABJI02000491_gene6928	7.778e-118	389.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158390_k127_3803208_10	1133849.O3I_026255	5.238e-72	252.0	COG0577@1|root,COG0577@2|Bacteria,2HHSC@201174|Actinobacteria,4FZWK@85025|Nocardiaceae	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_3803208_2	1121943.KB900000_gene1205	6.027e-283	897.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XHGI@135619|Oceanospirillales	135619|Oceanospirillales	P	cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_3803208_9	472759.Nhal_1948	3.244e-76	271.0	COG0475@1|root,COG0475@2|Bacteria,1R5QJ@1224|Proteobacteria,1RSM6@1236|Gammaproteobacteria,1WZK4@135613|Chromatiales	135613|Chromatiales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_3803208_15	1521187.JPIM01000071_gene2419	7.864e-10	63.0	COG0011@1|root,COG0011@2|Bacteria,2GAVT@200795|Chloroflexi,377F5@32061|Chloroflexia	32061|Chloroflexia	S	YKOF-related Family	-	-	-	-	-	-	-	-	-	-	-	-	Ykof
SRR25158390_k127_3803208_12	1240349.ANGC01000011_gene271	5.6e-46	175.0	COG0500@1|root,COG2226@2|Bacteria,2HFGE@201174|Actinobacteria,4FV65@85025|Nocardiaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_3803208_14	401053.AciPR4_2137	2.389e-10	66.0	COG2519@1|root,COG2519@2|Bacteria,3Y469@57723|Acidobacteria,2JIAQ@204432|Acidobacteriia	204432|Acidobacteriia	J	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_3803208_13	266264.Rmet_0990	3.722e-43	168.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,2VK53@28216|Betaproteobacteria,1K6RR@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_3803208_16	710686.Mycsm_04750	1.148e-05	48.0	COG0500@1|root,COG0500@2|Bacteria,2I3GX@201174|Actinobacteria,23FDZ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_3803208_6	1121272.KB903249_gene1628	1.147e-84	287.0	COG2020@1|root,COG2020@2|Bacteria,2GN9N@201174|Actinobacteria,4DDTM@85008|Micromonosporales	201174|Actinobacteria	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
SRR25158390_k127_3803208_7	469371.Tbis_0400	1.085e-83	298.0	28NT3@1|root,2ZBRV@2|Bacteria,2IIC3@201174|Actinobacteria,4E81U@85010|Pseudonocardiales	201174|Actinobacteria	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158390_k127_3803208_0	882083.SacmaDRAFT_4677	0.0	1042.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria,4E20Z@85010|Pseudonocardiales	201174|Actinobacteria	PQ	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158390_k127_3803208_3	1146883.BLASA_4884	1.31e-142	463.0	COG4243@1|root,COG4243@2|Bacteria,2HG56@201174|Actinobacteria,4ESMW@85013|Frankiales	201174|Actinobacteria	S	Vitamin k epoxide reductase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_3803208_5	1146883.BLASA_4883	5.365e-87	293.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria,4ESV7@85013|Frankiales	201174|Actinobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR,MarR_2
SRR25158390_k127_3803208_8	1146883.BLASA_4882	1.496e-80	276.0	COG3945@1|root,COG4309@1|root,COG3945@2|Bacteria,COG4309@2|Bacteria,2GS7C@201174|Actinobacteria,4ETE4@85013|Frankiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
SRR25158390_k127_3803208_4	405948.SACE_2450	1.29e-100	337.0	COG2239@1|root,COG2239@2|Bacteria,2I9TV@201174|Actinobacteria,4EEP1@85010|Pseudonocardiales	201174|Actinobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE
SRR25158390_k127_3803208_11	1304865.JAGF01000001_gene3292	1.311e-67	235.0	COG1309@1|root,COG1309@2|Bacteria,2GJZT@201174|Actinobacteria	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3803208_1	1304865.JAGF01000001_gene3293	0.0	1023.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4F0GU@85016|Cellulomonadaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_3813302_2	1122138.AQUZ01000004_gene1084	1.787e-162	520.0	COG0766@1|root,COG1396@1|root,COG0766@2|Bacteria,COG1396@2|Bacteria,2GJPW@201174|Actinobacteria,4DP2I@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
SRR25158390_k127_3813302_1	1298863.AUEP01000018_gene3880	2.677e-180	572.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DPAI@85009|Propionibacteriales	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158390_k127_3813302_4	1120950.KB892708_gene4177	4.873e-128	430.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4DWSG@85009|Propionibacteriales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158390_k127_3813302_8	196162.Noca_0141	2.101e-35	136.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,4DRQJ@85009|Propionibacteriales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158390_k127_3813302_0	110319.CF8_3966	2.48e-225	706.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4DTGI@85009|Propionibacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158390_k127_3813302_11	1122622.ATWJ01000011_gene2162	2.137e-15	81.0	2EGTM@1|root,33AJR@2|Bacteria,2GWY1@201174|Actinobacteria,4FHPK@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3813302_7	479432.Sros_2319	9.893e-94	312.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4EI4T@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3813302_3	479432.Sros_2321	9.945e-135	436.0	COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria,4EHRA@85012|Streptosporangiales	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158390_k127_3813302_6	446469.Sked_30730	2.395e-99	331.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria	201174|Actinobacteria	V	Transport permease protein	drrB	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158390_k127_3813302_5	1123024.AUII01000025_gene2106	1.262e-116	383.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJD@85010|Pseudonocardiales	201174|Actinobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	drrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_3813302_10	1445613.JALM01000009_gene821	2.317e-18	93.0	COG1309@1|root,COG1309@2|Bacteria,2INZP@201174|Actinobacteria,4E51Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158390_k127_3813302_9	1440053.JOEI01000010_gene5599	3.117e-25	109.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRR25158390_k127_3813302_12	1464048.JNZS01000012_gene3293	7.346e-07	55.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4D90Z@85008|Micromonosporales	201174|Actinobacteria	G	beta-galactosidase	bga1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRR25158390_k127_38215_2	479433.Caci_8382	8.115e-48	174.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158390_k127_38215_1	1120950.KB892801_gene1730	1.637e-98	339.0	COG1565@1|root,COG1565@2|Bacteria,2GKIU@201174|Actinobacteria,4DTE5@85009|Propionibacteriales	201174|Actinobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158390_k127_38215_0	1440053.JOEI01000042_gene3130	3.408e-226	713.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria	201174|Actinobacteria	D	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158390_k127_3822285_0	1120950.KB892708_gene4213	8.273e-267	830.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4DP25@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158390_k127_3822285_3	1136417.AZWE01000001_gene3776	4.451e-11	64.0	COG3677@1|root,COG3677@2|Bacteria,2GQKE@201174|Actinobacteria,4DGEE@85008|Micromonosporales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3822285_1	285535.JOEY01000015_gene4289	2.421e-84	289.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158390_k127_3822285_4	446466.Cfla_1734	1.681e-05	48.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4F0HX@85016|Cellulomonadaceae	201174|Actinobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SRR25158390_k127_382408_6	479432.Sros_3424	1.723e-71	263.0	COG2834@1|root,COG2834@2|Bacteria,2GKA2@201174|Actinobacteria,4EI6A@85012|Streptosporangiales	201174|Actinobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,MucB_RseB
SRR25158390_k127_382408_3	1122611.KB903944_gene1202	1.79e-109	362.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4EGJ6@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_382408_0	1120950.KB892769_gene5417	1.916e-115	390.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,4DWYJ@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_382408_5	1120950.KB892823_gene466	3.568e-72	249.0	29V8K@1|root,30GNI@2|Bacteria,2GM77@201174|Actinobacteria,4DR42@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_382408_4	110319.CF8_1223	5.001e-85	300.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4DP8Q@85009|Propionibacteriales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158390_k127_382408_2	58123.JOFJ01000015_gene4544	7.457e-110	362.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4EIEW@85012|Streptosporangiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158390_k127_382408_1	1246995.AFR_16540	4.317e-114	379.0	COG0477@1|root,COG2814@2|Bacteria,2GJKY@201174|Actinobacteria,4DAJG@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_382408_7	1056820.KB900683_gene11	2.961e-53	189.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_10,CBM_2,Glyco_hydro_6,PKD
SRR25158390_k127_3830673_1	1123322.KB904664_gene4002	4.626e-36	144.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158390_k127_3830673_0	329726.AM1_2067	8.556e-38	146.0	COG0454@1|root,COG0456@2|Bacteria,1G8P6@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_3837092_8	266117.Rxyl_1774	3.366e-22	100.0	COG0785@1|root,COG0785@2|Bacteria,2I8T6@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
SRR25158390_k127_3837092_3	1137269.AZWL01000001_gene5825	5.413e-70	243.0	2AXQV@1|root,31PRS@2|Bacteria,2I93X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_3837092_9	1121272.KB903249_gene1543	3.713e-20	97.0	2B63W@1|root,31Z0M@2|Bacteria,2H1I5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3837092_2	525368.HMPREF0591_2394	7.217e-80	274.0	COG1117@1|root,COG1117@2|Bacteria,2ID49@201174|Actinobacteria,2384V@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	pstB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158390_k127_3837092_1	262316.MAP_0575	8.902e-113	370.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,235M0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Permease component	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158390_k127_3837092_7	67356.KL575607_gene8858	3.862e-28	129.0	COG0723@1|root,COG0723@2|Bacteria,2I2JE@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158390_k127_3837092_4	1136417.AZWE01000017_gene911	4.447e-66	230.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria,4DCV8@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3837092_6	369723.Strop_1657	7.577e-32	134.0	2D0CU@1|root,32T8C@2|Bacteria,2GNI4@201174|Actinobacteria,4DF6V@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3837092_0	882083.SacmaDRAFT_3059	1.376e-156	504.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria,4E3BN@85010|Pseudonocardiales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158390_k127_3837092_5	1463917.JODC01000010_gene3887	2.523e-49	181.0	COG1881@1|root,COG1881@2|Bacteria,2IIR9@201174|Actinobacteria	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158390_k127_3838762_16	1449976.KALB_1222	1.741e-48	179.0	COG0583@1|root,COG0583@2|Bacteria,2I9RK@201174|Actinobacteria,4E17U@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_3838762_17	543632.JOJL01000042_gene4627	5.676e-48	176.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_3838762_2	471853.Bcav_0785	1.015e-170	544.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158390_k127_3838762_4	471853.Bcav_0782	5.967e-168	537.0	COG3642@1|root,COG3642@2|Bacteria,2GIX0@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158390_k127_3838762_21	1278078.G419_14097	2.689e-11	71.0	COG5164@1|root,COG5164@2|Bacteria,2GR5S@201174|Actinobacteria,4G83S@85025|Nocardiaceae	201174|Actinobacteria	K	Domain of unknown function (DUF4282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4282
SRR25158390_k127_3838762_5	28042.GU90_03305	1.979e-158	509.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DXHT@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_3838762_9	479431.Namu_4924	2.004e-109	362.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4ERH3@85013|Frankiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158390_k127_3838762_0	1033730.CAHG01000008_gene3234	3.437e-214	679.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4DP8C@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158390_k127_3838762_18	926564.KI911625_gene4036	5.951e-39	156.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K09824,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	NUDIX,PAP2
SRR25158390_k127_3838762_12	2074.JNYD01000009_gene5237	1.537e-63	229.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4E2MV@85010|Pseudonocardiales	201174|Actinobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3581c	YgbB
SRR25158390_k127_3838762_13	479433.Caci_8146	7.239e-62	221.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158390_k127_3838762_10	1048339.KB913029_gene2036	1.15e-84	283.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4ES60@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, CarD family	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158390_k127_3838762_15	479432.Sros_5948	1.398e-58	215.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria,4ENNX@85012|Streptosporangiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158390_k127_3838762_8	1120950.KB892790_gene2079	3.683e-115	379.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4DNN6@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_3838762_7	1122138.AQUZ01000062_gene5827	8.553e-125	410.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4DP15@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158390_k127_3838762_11	1120950.KB892790_gene2081	1.005e-66	233.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4DQEB@85009|Propionibacteriales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158390_k127_3838762_6	1120950.KB892790_gene2083	9.764e-135	433.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4DND2@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158390_k127_3838762_14	1172180.KB911796_gene8122	1.328e-59	220.0	2AZ39@1|root,32T7B@2|Bacteria,2I35K@201174|Actinobacteria	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158390_k127_3838762_3	479432.Sros_0956	1.331e-168	545.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4EFJR@85012|Streptosporangiales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_3838762_20	1382306.JNIM01000001_gene2489	1.204e-30	130.0	2C5C8@1|root,345UA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3838762_1	930169.B5T_00549	5.319e-191	624.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3838762_19	28444.JODQ01000007_gene5712	2.139e-32	128.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4EG3R@85012|Streptosporangiales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158390_k127_38452_2	1150864.MILUP08_41766	3.128e-61	222.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4DBF1@85008|Micromonosporales	201174|Actinobacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
SRR25158390_k127_38452_1	644283.Micau_1663	6.98e-121	398.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria,4D9ZB@85008|Micromonosporales	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
SRR25158390_k127_38452_0	644283.Micau_1662	2.019e-165	532.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4DAQW@85008|Micromonosporales	201174|Actinobacteria	G	extracellular solute-binding protein, family 1	-	-	-	ko:K10240	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	SBP_bac_8
SRR25158390_k127_3853913_7	644966.Tmar_1595	8.573e-51	188.0	COG1622@1|root,COG1622@2|Bacteria,1TRC3@1239|Firmicutes,25348@186801|Clostridia	186801|Clostridia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRR25158390_k127_3853913_1	644966.Tmar_1596	2.849e-222	718.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,24YCV@186801|Clostridia	186801|Clostridia	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.10.3.12,1.9.3.1	ko:K02274,ko:K02827	ko00190,ko01100,map00190,map01100	M00155,M00416	R00081,R09492	RC00016,RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158390_k127_3853913_17	1174528.JH992898_gene4454	7.465e-06	55.0	COG1845@1|root,COG1845@2|Bacteria,1FZY8@1117|Cyanobacteria,1JKMJ@1189|Stigonemataceae	1117|Cyanobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158390_k127_3853913_2	1283283.ATXA01000001_gene941	5.721e-111	368.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4ERCX@85013|Frankiales	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158390_k127_3853913_14	479434.Sthe_0183	3.027e-15	85.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158390_k127_3853913_5	926560.KE387025_gene3982	8.2e-80	277.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3853913_10	926560.KE387025_gene3980	8.187e-38	158.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_3853913_6	1289387.AUKW01000023_gene3046	3.059e-69	241.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_3853913_3	1206737.BAGF01000144_gene5739	3.194e-106	349.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4G72A@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
SRR25158390_k127_3853913_0	1206737.BAGF01000144_gene5738	3.041e-278	878.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_3853913_11	1449347.JQLN01000001_gene543	1.629e-36	143.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria,2M5E4@2063|Kitasatospora	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158390_k127_3853913_4	1463858.JOHR01000003_gene1840	1.964e-82	284.0	COG0543@1|root,COG0543@2|Bacteria,2HXFY@201174|Actinobacteria	201174|Actinobacteria	CH	Oxidoreductase	asrB	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158390_k127_3853913_8	35754.JNYJ01000042_gene1376	1.45e-43	165.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria,4DF04@85008|Micromonosporales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158390_k127_3853913_15	1348663.KCH_74150	5.069e-15	82.0	2F8CX@1|root,340RU@2|Bacteria,2GTM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3853913_13	471852.Tcur_3812	1.829e-27	121.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4EPZ3@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3853913_9	101510.RHA1_ro11235	4.102e-43	160.0	COG0599@1|root,COG0599@2|Bacteria,2IRPW@201174|Actinobacteria,4G1W2@85025|Nocardiaceae	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_3853913_12	1120950.KB892757_gene6509	2.342e-29	119.0	2EH65@1|root,3351X@2|Bacteria,2GQUG@201174|Actinobacteria,4DSRR@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876
SRR25158390_k127_3854455_1	1229780.BN381_220012	3.845e-11	66.0	COG2801@1|root,COG2801@2|Bacteria,2IEHA@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
SRR25158390_k127_3854455_0	1123251.ATWM01000016_gene1407	1.671e-15	80.0	2E3WU@1|root,32YU0@2|Bacteria,2GTJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3854455_2	40571.JOEA01000024_gene7371	1.929e-05	51.0	COG2253@1|root,COG2253@2|Bacteria,2GP8Y@201174|Actinobacteria,4E303@85010|Pseudonocardiales	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158390_k127_3854455_3	1156844.KB891808_gene1421	4.131e-05	49.0	COG2253@1|root,COG2253@2|Bacteria,2GP8Y@201174|Actinobacteria	201174|Actinobacteria	K	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158390_k127_389224_6	285535.JOEY01000006_gene8261	4.31e-76	259.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_389224_9	644283.Micau_3474	4.282e-59	209.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4DG1J@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158390_k127_389224_7	269800.Tfu_1919	8.858e-75	261.0	COG0730@1|root,COG0730@2|Bacteria,2IIY7@201174|Actinobacteria,4EJN8@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_389224_0	1298863.AUEP01000004_gene2120	2.287e-267	833.0	COG0488@1|root,COG0488@2|Bacteria,2GMUD@201174|Actinobacteria,4DNQ6@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_389224_4	58344.JOEL01000002_gene1930	9.284e-93	312.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158390_k127_389224_3	42256.RradSPS_0363	1.244e-93	317.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4CRP7@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2
SRR25158390_k127_389224_10	926560.KE387023_gene2381	1.261e-47	178.0	COG1309@1|root,COG1309@2|Bacteria,1WKWZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_389224_5	1304865.JAGF01000001_gene181	3.05e-81	281.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4F0PA@85016|Cellulomonadaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158390_k127_389224_8	1089546.AQUI01000002_gene1692	4.405e-63	220.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,408JV@622450|Actinopolysporales	201174|Actinobacteria	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158390_k127_389224_11	1298863.AUEP01000008_gene1328	2.678e-41	156.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4DQUX@85009|Propionibacteriales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158390_k127_389224_12	1386089.N865_13265	1.52e-21	107.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4FHDA@85021|Intrasporangiaceae	201174|Actinobacteria	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SRR25158390_k127_389224_2	66875.JODY01000044_gene2752	1.357e-96	322.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria	201174|Actinobacteria	H	PFAM Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158390_k127_389224_1	443255.SCLAV_0265	3.304e-134	444.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iNJ661.Rv2051c	CN_hydrolase
SRR25158390_k127_389224_13	1449347.JQLN01000004_gene6389	0.0001134	46.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,2M1XW@2063|Kitasatospora	201174|Actinobacteria	S	Amidohydrolase family	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158390_k127_3894942_1	1123251.ATWM01000010_gene2985	3.194e-20	100.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria,4FIJ4@85021|Intrasporangiaceae	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRR25158390_k127_3894942_0	1121952.ATXT01000014_gene1396	1.879e-36	146.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4FMKW@85023|Microbacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_3897771_4	1298863.AUEP01000015_gene1799	3.419e-48	177.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4DPBR@85009|Propionibacteriales	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158390_k127_3897771_3	1123023.JIAI01000022_gene2280	1.827e-53	202.0	COG5340@1|root,COG5340@2|Bacteria,2I56S@201174|Actinobacteria,4EEAV@85010|Pseudonocardiales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
SRR25158390_k127_3897771_2	1120950.KB892762_gene5482	2.657e-105	362.0	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria,4DQ6A@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_3897771_8	1120950.KB892762_gene5481	2.129e-21	98.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,4DSE1@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158390_k127_3897771_0	644283.Micau_2660	2.588e-305	967.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4D9ZF@85008|Micromonosporales	201174|Actinobacteria	CP	Na H antiporter	mrpA/mrpB	-	1.6.5.3	ko:K00341,ko:K05565,ko:K14086	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
SRR25158390_k127_3897771_5	1123065.ATWL01000006_gene2226	3.601e-39	151.0	COG1006@1|root,COG1006@2|Bacteria,2ISBC@201174|Actinobacteria	201174|Actinobacteria	P	Multisubunit Na H antiporter MnhC subunit	mrpC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
SRR25158390_k127_3897771_1	44060.JODL01000007_gene1316	2.663e-198	632.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria	201174|Actinobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158390_k127_3897771_6	1380354.JIAN01000005_gene2116	5.943e-36	143.0	COG1863@1|root,COG1863@2|Bacteria,2IQD6@201174|Actinobacteria,4F1CC@85016|Cellulomonadaceae	201174|Actinobacteria	P	Na+/H+ ion antiporter subunit	mrpE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
SRR25158390_k127_3897771_9	1122939.ATUD01000001_gene137	1.89e-17	87.0	COG2212@1|root,COG2212@2|Bacteria,2GRIE@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Multiple resistance and pH regulation protein F	mrpF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
SRR25158390_k127_3897771_7	471856.Jden_2434	2.706e-27	119.0	COG1320@1|root,COG1320@2|Bacteria,2IQXD@201174|Actinobacteria	201174|Actinobacteria	P	monovalent cation proton antiporter, MnhG PhaG subunit	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
SRR25158390_k127_3912587_5	1306174.JODP01000013_gene7744	1.476e-08	57.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_3912587_2	367299.JOEE01000010_gene3308	1.768e-90	310.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4FEBG@85021|Intrasporangiaceae	201174|Actinobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158390_k127_3912587_1	1120950.KB892707_gene4910	2.112e-156	505.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4DPP5@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_3912587_0	1003195.SCAT_1174	6.012e-180	574.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158390_k127_3912587_3	1229780.BN381_290084	7.008e-69	262.0	COG1215@1|root,COG3119@1|root,COG1215@2|Bacteria,COG3119@2|Bacteria,2H59R@201174|Actinobacteria	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3912587_4	1210045.ALNP01000009_gene4750	1.563e-54	196.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158390_k127_391892_2	2002.JOEQ01000001_gene4644	2.183e-47	178.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4EJ0G@85012|Streptosporangiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158390_k127_391892_0	1155718.KB891940_gene4825	6.637e-71	252.0	COG0332@1|root,COG0332@2|Bacteria,2HFCQ@201174|Actinobacteria	201174|Actinobacteria	I	synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158390_k127_391892_1	1463821.JOGR01000014_gene3462	1.642e-63	224.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_394170_22	443255.SCLAV_0728	3.828e-63	227.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria	201174|Actinobacteria	E	Shikimate dehydrogenase	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
SRR25158390_k127_394170_13	1048339.KB913029_gene3959	3.114e-91	313.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4ESC2@85013|Frankiales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158390_k127_394170_27	981369.JQMJ01000004_gene4187	1.332e-47	176.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,2NI6I@228398|Streptacidiphilus	201174|Actinobacteria	L	Holliday junction resolvase	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158390_k127_394170_1	1048339.KB913029_gene3957	0.0	1112.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4ERRJ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158390_k127_394170_33	1120950.KB892708_gene4295	1.041e-11	71.0	2EGGE@1|root,33A8E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_394170_32	405948.SACE_2050	1.313e-24	108.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4E3ET@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR25158390_k127_394170_3	397278.JOJN01000004_gene1314	6.463e-188	597.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4DP5Q@85009|Propionibacteriales	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158390_k127_394170_5	235985.BBPN01000017_gene5705	2.392e-133	430.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,2NFMA@228398|Streptacidiphilus	201174|Actinobacteria	J	tRNA methyltransferase complex GCD14 subunit N-term	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158390_k127_394170_12	1122611.KB904018_gene6973	6.307e-98	332.0	COG1994@1|root,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4EG4K@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR25158390_k127_394170_7	1120950.KB892708_gene4421	1.465e-120	395.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,4DP6M@85009|Propionibacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF2800)	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158390_k127_394170_18	479432.Sros_8961	9.27e-70	247.0	COG2602@1|root,COG2602@2|Bacteria,2ID9U@201174|Actinobacteria,4EI9H@85012|Streptosporangiales	201174|Actinobacteria	V	Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
SRR25158390_k127_394170_34	1366050.N234_00135	8.566e-11	67.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VMHC@28216|Betaproteobacteria,1K31U@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_394170_35	443255.SCLAV_1996	4.552e-05	50.0	28S86@1|root,2ZEJI@2|Bacteria,2IQGN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_394170_26	1236902.ANAS01000005_gene4679	1.295e-48	183.0	COG0706@1|root,COG0706@2|Bacteria,2GIRJ@201174|Actinobacteria,4EJQI@85012|Streptosporangiales	201174|Actinobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158390_k127_394170_8	312284.A20C1_09934	2.909e-117	387.0	COG0644@1|root,COG0644@2|Bacteria,2HG44@201174|Actinobacteria,3UXPV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158390_k127_394170_15	935839.JAGJ01000003_gene1579	1.251e-71	252.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,4F4FE@85017|Promicromonosporaceae	201174|Actinobacteria	S	Phospholipid methyltransferase	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
SRR25158390_k127_394170_6	1120936.KB907208_gene1220	1.299e-127	418.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4EGRI@85012|Streptosporangiales	201174|Actinobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	pks11	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR25158390_k127_394170_24	1120950.KB892776_gene811	5.705e-52	191.0	COG1309@1|root,COG1309@2|Bacteria,2I31S@201174|Actinobacteria,4DR56@85009|Propionibacteriales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158390_k127_394170_9	1120950.KB892776_gene810	4.544e-105	346.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria,4DSJJ@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Lactamase_B
SRR25158390_k127_394170_29	1463901.JOIY01000005_gene1756	3.131e-43	166.0	2CDI4@1|root,32YR4@2|Bacteria,2IINI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_394170_0	882082.SaccyDRAFT_1570	0.0	1370.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4DXCZ@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158390_k127_394170_14	1122611.KB903939_gene401	1.214e-84	286.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4EHKT@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_394170_19	67352.JODS01000039_gene6785	8.395e-68	233.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised ACR, COG1259	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158390_k127_394170_16	351607.Acel_1225	1.386e-71	250.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4ESMT@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MerR	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158390_k127_394170_20	1120950.KB892707_gene5033	9.981e-67	232.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DR1A@85009|Propionibacteriales	201174|Actinobacteria	T	zinc-ribbon domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158390_k127_394170_25	110319.CF8_2035	8.417e-49	183.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4DR4B@85009|Propionibacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158390_k127_394170_31	369723.Strop_2384	1.067e-30	132.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4DD3G@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158390_k127_394170_30	1306174.JODP01000002_gene5961	3.215e-38	150.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein (small basic protein)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158390_k127_394170_28	1120950.KB892707_gene5029	1.362e-43	169.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4DR0G@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158390_k127_394170_17	479435.Kfla_3168	2.748e-71	246.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4DQ8M@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_394170_10	66874.JOFS01000011_gene280	5.803e-101	344.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_394170_2	1121946.AUAX01000005_gene5553	7.186e-276	860.0	COG1960@1|root,COG1960@2|Bacteria,2GJIB@201174|Actinobacteria,4DI8S@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase N terminal	fadE5	-	1.3.8.1	ko:K00248,ko:K20035	ko00071,ko00280,ko00650,ko00920,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map00920,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751,R11130	RC00052,RC00068,RC00076,RC00120,RC00148,RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRR25158390_k127_394170_23	1121946.AUAX01000005_gene5554	2.782e-58	209.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria,4DG7B@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_394170_11	211114.JOEF01000004_gene6505	5.22e-100	348.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4DXV2@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_394170_21	1121272.KB903251_gene618	1.791e-64	224.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4DEP7@85008|Micromonosporales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158390_k127_394170_4	1121946.AUAX01000005_gene5556	1.357e-133	433.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4DC8F@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_3949781_11	644283.Micau_5744	3.061e-08	54.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4DAMJ@85008|Micromonosporales	201174|Actinobacteria	C	Fad linked oxidase	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_3949781_5	929712.KI912613_gene2770	1.961e-118	392.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4CSJZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158390_k127_3949781_6	110319.CF8_2544	1.413e-99	341.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQY1@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_3949781_4	479435.Kfla_0102	5.098e-121	398.0	COG0494@1|root,COG1670@1|root,COG0494@2|Bacteria,COG1670@2|Bacteria,2IGFH@201174|Actinobacteria,4DTN8@85009|Propionibacteriales	201174|Actinobacteria	JL	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,NUDIX
SRR25158390_k127_3949781_3	1120950.KB892785_gene251	7.217e-126	419.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4DNA7@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_3949781_1	471853.Bcav_0209	1.979e-279	862.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_3949781_2	1120950.KB892785_gene249	2.938e-158	503.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DNUJ@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158390_k127_3949781_9	1353531.AZNX01000005_gene3276	2.234e-52	200.0	COG1277@1|root,COG1277@2|Bacteria,1R5P4@1224|Proteobacteria	1224|Proteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158390_k127_3949781_7	1382315.JPOI01000001_gene238	4.443e-92	315.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,4H9RS@91061|Bacilli	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3949781_8	926569.ANT_28220	2.071e-55	208.0	COG1470@1|root,COG1470@2|Bacteria,2G5KU@200795|Chloroflexi	200795|Chloroflexi	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
SRR25158390_k127_3949781_0	103733.JNYO01000033_gene7222	6.158e-284	882.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2HFU4@201174|Actinobacteria,4E1S6@85010|Pseudonocardiales	201174|Actinobacteria	J	Glycyl-tRNA synthetase alpha subunit	glyS	-	6.1.1.14	ko:K01879,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA-synt_2e,tRNA_synt_2f
SRR25158390_k127_3953798_7	1120936.KB907221_gene2175	5.184e-54	198.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3953798_2	1394178.AWOO02000031_gene4787	2.262e-170	549.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria	201174|Actinobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158390_k127_3953798_0	1380356.JNIK01000013_gene4207	1.868e-185	587.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ERKI@85013|Frankiales	201174|Actinobacteria	U	type II secretion system protein E	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158390_k127_3953798_4	1120950.KB892764_gene5642	2.397e-95	323.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,4DNMD@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_3953798_5	1120950.KB892764_gene5643	6.96e-90	321.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4DP2Z@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158390_k127_3953798_10	1120958.AULD01000006_gene281	3.329e-11	65.0	2EG89@1|root,33A03@2|Bacteria,2GX3U@201174|Actinobacteria,4FQQM@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3953798_9	1151122.AQYD01000005_gene3636	1.331e-20	98.0	2CXFQ@1|root,32T1V@2|Bacteria,2GQYH@201174|Actinobacteria,4FPHR@85023|Microbacteriaceae	201174|Actinobacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158390_k127_3953798_8	1120950.KB892764_gene5646	9.089e-24	108.0	2E9Y4@1|root,3343S@2|Bacteria,2GR3H@201174|Actinobacteria,4DRMM@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3953798_11	1120950.KB892764_gene5647	6.746e-10	67.0	2EBSZ@1|root,335SP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158390_k127_3953798_1	66373.JOFQ01000011_gene7289	2.196e-176	561.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158390_k127_3953798_3	1123320.KB889677_gene2736	5.804e-116	376.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158390_k127_3953798_6	1906.SFRA_24375	1.73e-81	280.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158390_k127_3956393_10	909613.UO65_3332	8.193e-14	71.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4DX6B@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158390_k127_3956393_3	1463856.JOHY01000065_gene5475	1.799e-108	356.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158390_k127_3956393_1	196162.Noca_4347	6.749e-197	626.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4DNHS@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158390_k127_3956393_5	1048339.KB913029_gene2292	4.97e-70	243.0	COG1246@1|root,COG1246@2|Bacteria,2GJBT@201174|Actinobacteria,4ESNZ@85013|Frankiales	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	argA	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_3956393_7	66377.JOBH01000010_gene6477	4.659e-31	126.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria	201174|Actinobacteria	S	pathogenesis	lsr	-	-	-	-	-	-	-	-	-	-	-	Lsr2
SRR25158390_k127_3956393_8	1122604.JONR01000017_gene4344	3.947e-25	114.0	COG4221@1|root,COG4221@2|Bacteria,1NTNU@1224|Proteobacteria,1SD1N@1236|Gammaproteobacteria,1XA8P@135614|Xanthomonadales	135614|Xanthomonadales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3956393_6	2002.JOEQ01000021_gene6828	1.021e-58	225.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,4EJKK@85012|Streptosporangiales	201174|Actinobacteria	S	LUD domain	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158390_k127_3956393_0	298655.KI912266_gene2345	1.564e-220	702.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4ERCA@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM iron-sulfur cluster binding protein	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158390_k127_3956393_2	1283283.ATXA01000003_gene1634	1.617e-113	372.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4EUMB@85013|Frankiales	201174|Actinobacteria	C	Cysteine-rich domain	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158390_k127_3956393_4	1869.MB27_38905	4.554e-89	294.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4D8QE@85008|Micromonosporales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158390_k127_3961544_2	357808.RoseRS_3003	1.121e-66	234.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi,374XR@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_3961544_1	204669.Acid345_4350	5.051e-128	423.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158390_k127_3961544_3	290397.Adeh_1821	5.987e-54	211.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria,2Z30D@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158390_k127_3961544_0	867903.ThesuDRAFT_01029	4.574e-141	467.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_3961544_4	472759.Nhal_0105	1.087e-34	139.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,1T1MS@1236|Gammaproteobacteria,1WX38@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158390_k127_3975631_2	1121272.KB903290_gene4574	3.108e-68	239.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4D9VC@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158390_k127_3975631_1	1121272.KB903290_gene4575	1.274e-97	332.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DCNR@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_3975631_0	479435.Kfla_6943	4.961e-179	570.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DPK2@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_3979768_0	1246995.AFR_03125	8.598e-89	295.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,4DHC8@85008|Micromonosporales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_3979768_1	1150864.MILUP08_46347	5.699e-82	280.0	2E9ND@1|root,333UW@2|Bacteria,2GU6J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3979768_2	356851.JOAN01000013_gene5729	4.826e-09	59.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3980793_0	1120950.KB892790_gene2114	0.0	1090.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DN9Q@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_3988124_0	1380393.JHVP01000006_gene3947	1.668e-170	560.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4ERKW@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_3990387_3	73044.JNXP01000002_gene2185	3.622e-109	367.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_3990387_8	1463917.JODC01000003_gene5613	1.197e-55	197.0	COG0346@1|root,COG0346@2|Bacteria,2IKRF@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3990387_9	1237500.ANBA01000004_gene2160	2.082e-42	158.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4EQ3W@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_3990387_4	1068980.ARVW01000001_gene7475	2.008e-68	236.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4E2S3@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158390_k127_3990387_6	656024.FsymDg_2740	8.842e-62	226.0	COG0346@1|root,COG0346@2|Bacteria,2IHYP@201174|Actinobacteria,4ESJ7@85013|Frankiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_3990387_7	2045.KR76_13580	1.172e-61	215.0	COG3576@1|root,COG3576@2|Bacteria,2IG3P@201174|Actinobacteria,4DSD0@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_3990387_5	37919.EP51_22485	9.256e-68	233.0	COG3945@1|root,COG3945@2|Bacteria,2IFPE@201174|Actinobacteria,4G2SF@85025|Nocardiaceae	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_3990387_0	1146883.BLASA_4604	0.0	1301.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ES2X@85013|Frankiales	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_3990387_10	656024.FsymDg_0596	2.148e-42	160.0	COG1848@1|root,COG1848@2|Bacteria,2GUVQ@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3990387_12	450380.JPSY01000001_gene1646	8.567e-21	94.0	COG2002@1|root,COG2002@2|Bacteria,2GWQF@201174|Actinobacteria	201174|Actinobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158390_k127_3990387_2	479435.Kfla_3539	1.195e-120	391.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria,4DR4S@85009|Propionibacteriales	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3990387_1	471853.Bcav_2086	5.459e-124	401.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158390_k127_3990766_9	391037.Sare_3486	8.76e-39	152.0	COG3448@1|root,COG4175@1|root,COG3448@2|Bacteria,COG4175@2|Bacteria,2GJC0@201174|Actinobacteria,4DGRA@85008|Micromonosporales	201174|Actinobacteria	E	TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158390_k127_3990766_4	882083.SacmaDRAFT_3038	7.973e-102	338.0	COG4176@1|root,COG4176@2|Bacteria,2GKRF@201174|Actinobacteria,4DZ6P@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system, permease component	opuAB	-	-	ko:K02001,ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158390_k127_3990766_2	882083.SacmaDRAFT_3037	2.275e-112	372.0	COG2113@1|root,COG2113@2|Bacteria,2I2IV@201174|Actinobacteria,4E0PR@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type proline glycine betaine transport	opuAC	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158390_k127_3990766_3	479435.Kfla_6822	1.082e-106	347.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4DNI0@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158390_k127_3990766_0	1122622.ATWJ01000011_gene2287	0.0	1026.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4FEZN@85021|Intrasporangiaceae	201174|Actinobacteria	C	Fe-S oxidoreductase	fadF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158390_k127_3990766_7	298655.KI912266_gene6056	7.283e-67	233.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_3990766_5	101510.RHA1_ro05054	1.76e-97	338.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,4FZ0G@85025|Nocardiaceae	201174|Actinobacteria	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173,HAMP,HATPase_c,HisKA
SRR25158390_k127_3990766_1	1449976.KALB_3130	3.494e-116	386.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,4DZ8C@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173,HAMP,HATPase_c,HisKA
SRR25158390_k127_3990766_6	1150864.MILUP08_30111	1.296e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DB59@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	cseB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_3990766_10	1298863.AUEP01000011_gene507	1.019e-33	136.0	COG4226@1|root,COG4226@2|Bacteria,2IKXB@201174|Actinobacteria,4DS17@85009|Propionibacteriales	201174|Actinobacteria	S	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB,RHH_1
SRR25158390_k127_3990766_11	1449048.JQKU01000007_gene233	2.96e-30	131.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,23889@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158390_k127_3990766_8	1380347.JNII01000005_gene3244	4.405e-63	220.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4ES63@85013|Frankiales	201174|Actinobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158390_k127_4001717_0	479435.Kfla_1793	7.428e-151	485.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4DPR6@85009|Propionibacteriales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_4001717_1	1120950.KB892760_gene5788	4.046e-113	366.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DNHH@85009|Propionibacteriales	201174|Actinobacteria	F	Adenosine/AMP deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158390_k127_4002200_0	1172179.AUKV01000049_gene6896	1.085e-25	110.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR25158390_k127_4002200_1	13690.CP98_03696	0.0002243	51.0	COG2442@1|root,COG2442@2|Bacteria,1RIWP@1224|Proteobacteria,2U9YN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
SRR25158390_k127_401023_0	1179773.BN6_30930	0.0	1112.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DY9U@85010|Pseudonocardiales	201174|Actinobacteria	C	aconitate hydratase	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158390_k127_4014076_0	861299.J421_0695	9.135e-233	739.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158390_k127_4015832_12	502025.Hoch_2002	5.517e-47	174.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158390_k127_4015832_9	675635.Psed_2653	8.006e-62	219.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E2ZA@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158390_k127_4015832_0	502025.Hoch_2000	0.0	1201.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR25158390_k127_4015832_8	196162.Noca_0231	1.639e-68	244.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2IA9U@201174|Actinobacteria,4DUZB@85009|Propionibacteriales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158390_k127_4015832_4	1192868.CAIU01000020_gene2800	5.829e-88	318.0	COG2113@1|root,COG2113@2|Bacteria,1MWZU@1224|Proteobacteria,2TSYB@28211|Alphaproteobacteria,43HR3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Substrate binding domain of ABC-type glycine betaine transport system	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158390_k127_4015832_5	118168.MC7420_7834	2.201e-81	298.0	COG0834@1|root,COG0834@2|Bacteria,1G36J@1117|Cyanobacteria,1HBPC@1150|Oscillatoriales	1117|Cyanobacteria	ET	amino acid ABC transporter substrate-binding protein, PAAT family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	Ion_trans_2,Lig_chan,SBP_bac_3
SRR25158390_k127_4015832_13	1237500.ANBA01000024_gene2108	2.564e-43	164.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,4EQI1@85012|Streptosporangiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_4015832_6	590998.Celf_1110	3.461e-76	261.0	COG0572@1|root,COG0572@2|Bacteria,2GMCP@201174|Actinobacteria	201174|Actinobacteria	F	PFAM AIG2 family protein	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158390_k127_4015832_3	590998.Celf_2295	6.935e-114	372.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4F27Z@85016|Cellulomonadaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4015832_2	266117.Rxyl_0206	2.124e-125	433.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4CR1A@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_4015832_10	314256.OG2516_16029	1.855e-55	221.0	COG1129@1|root,COG1129@2|Bacteria,1PF40@1224|Proteobacteria,2V7FI@28211|Alphaproteobacteria,2PF7J@252301|Oceanicola	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158390_k127_4015832_1	1122214.AQWH01000008_gene1567	2.46e-128	428.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,2PK99@255475|Aurantimonadaceae	28211|Alphaproteobacteria	G	import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158390_k127_4015832_7	314256.OG2516_16034	2.479e-73	263.0	COG1879@1|root,COG1879@2|Bacteria,1PI95@1224|Proteobacteria,2VD0X@28211|Alphaproteobacteria,2PFP9@252301|Oceanicola	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
SRR25158390_k127_4015832_11	1122214.AQWH01000008_gene1568	6.468e-53	207.0	COG1172@1|root,COG1172@2|Bacteria,1MX1K@1224|Proteobacteria,2TUYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158390_k127_4015832_14	266117.Rxyl_0206	6.928e-33	135.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4CR1A@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_4023573_0	479435.Kfla_3089	5.733e-299	932.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4DNJG@85009|Propionibacteriales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158390_k127_4023573_1	1122138.AQUZ01000024_gene7725	7.596e-60	225.0	COG0741@1|root,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4DX3A@85009|Propionibacteriales	201174|Actinobacteria	M	Membrane-bound lytic murein transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158390_k127_4023573_2	1048339.KB913029_gene4519	1.256e-15	82.0	COG2244@1|root,COG2244@2|Bacteria,2GJV2@201174|Actinobacteria,4EVSZ@85013|Frankiales	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
SRR25158390_k127_4028843_1	1380393.JHVP01000005_gene3774	2.171e-141	456.0	COG2017@1|root,COG2017@2|Bacteria,2GME9@201174|Actinobacteria,4ETYE@85013|Frankiales	201174|Actinobacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158390_k127_4028843_0	472759.Nhal_3183	1.403e-183	584.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RY35@1236|Gammaproteobacteria,1X09U@135613|Chromatiales	135613|Chromatiales	H	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_403373_2	67373.JOBF01000003_gene593	4.277e-158	506.0	COG0673@1|root,COG0673@2|Bacteria,2GKIB@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	xdh	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019321,GO:0019323,GO:0022607,GO:0036094,GO:0042732,GO:0042843,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0047837,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_403373_1	928724.SacglDRAFT_01207	6.66e-176	564.0	COG0329@1|root,COG0329@2|Bacteria,2GJEU@201174|Actinobacteria,4DXJN@85010|Pseudonocardiales	201174|Actinobacteria	EM	Protein of unknown function (DUF993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF993
SRR25158390_k127_403373_3	1089545.KB913037_gene2248	6.547e-120	391.0	COG1082@1|root,COG1082@2|Bacteria,2GJVP@201174|Actinobacteria,4E0VR@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158390_k127_403373_0	196162.Noca_1675	2.185e-301	940.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DNCN@85009|Propionibacteriales	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
SRR25158390_k127_4036342_2	1380354.JIAN01000009_gene3867	1.257e-148	475.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4F25R@85016|Cellulomonadaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_4036342_3	743718.Isova_2808	7.781e-135	442.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4F3CE@85017|Promicromonosporaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
SRR25158390_k127_4036342_4	743718.Isova_2807	2.89e-128	417.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4F3D3@85017|Promicromonosporaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	M00196,M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.39	-	-	BPD_transp_1
SRR25158390_k127_4036342_11	479435.Kfla_5620	1.087e-40	163.0	2B5R0@1|root,31YKI@2|Bacteria,2IPMA@201174|Actinobacteria,4DR93@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4036342_12	1120950.KB892763_gene5546	4.404e-31	126.0	COG3877@1|root,COG3877@2|Bacteria,2IT3M@201174|Actinobacteria,4DVDP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR25158390_k127_4036342_5	1123322.KB904635_gene2587	2.392e-124	413.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_4036342_6	479435.Kfla_5617	9.349e-105	347.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4DQ35@85009|Propionibacteriales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_4036342_8	1120950.KB892763_gene5547	2.952e-64	224.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4DQI3@85009|Propionibacteriales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158390_k127_4036342_13	1206732.BAGD01000106_gene4777	5.463e-06	53.0	2DRBP@1|root,33B4I@2|Bacteria,2IGPY@201174|Actinobacteria,4G20Q@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4307
SRR25158390_k127_4036342_1	479435.Kfla_5614	3.726e-149	483.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DP8N@85009|Propionibacteriales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158390_k127_4036342_7	743718.Isova_1207	9.537e-102	355.0	COG0477@1|root,COG2814@2|Bacteria,2H012@201174|Actinobacteria,4F5P8@85017|Promicromonosporaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08159	-	-	-	-	ko00000,ko02000	2.A.1.2.15,2.A.1.2.18	-	-	MFS_1,Sugar_tr
SRR25158390_k127_4036342_9	743718.Isova_1206	4.545e-50	181.0	COG0789@1|root,COG0789@2|Bacteria,2IQ62@201174|Actinobacteria,4F4YZ@85017|Promicromonosporaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_4036342_0	471853.Bcav_3705	5.007e-279	874.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria	201174|Actinobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158390_k127_4036342_10	1120950.KB892779_gene981	4.174e-44	162.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DQ8R@85009|Propionibacteriales	201174|Actinobacteria	S	Haemolysin-III related	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158390_k127_4047066_11	1121017.AUFG01000001_gene2910	4.702e-19	90.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4FF17@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_4047066_9	1283283.ATXA01000003_gene1379	2.929e-32	129.0	2E6TR@1|root,331DK@2|Bacteria,2IQF8@201174|Actinobacteria,4ET8F@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4047066_1	1394178.AWOO02000084_gene1153	6.167e-166	537.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4EHZN@85012|Streptosporangiales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158390_k127_4047066_2	1033730.CAHG01000016_gene387	1.415e-158	507.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DN5V@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage system T protein	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158390_k127_4047066_8	1463920.JOGB01000054_gene4494	2.201e-33	147.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2207	CobU,DBI_PRT
SRR25158390_k127_4047066_12	1003195.SCAT_1297	1.508e-16	81.0	2EFWK@1|root,339NW@2|Bacteria,2IQXQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4047066_0	479435.Kfla_5910	1.009e-201	639.0	COG2141@1|root,COG4639@1|root,COG2141@2|Bacteria,COG4639@2|Bacteria,2GM7W@201174|Actinobacteria,4DPZ7@85009|Propionibacteriales	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRR25158390_k127_4047066_6	909613.UO65_3743	1.229e-37	147.0	COG0454@1|root,COG0456@2|Bacteria,2IFF2@201174|Actinobacteria,4E3HI@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_4047066_7	1122609.AUGT01000022_gene745	5.407e-34	138.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4DRVQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
SRR25158390_k127_4047066_3	1120950.KB892707_gene4776	3.596e-106	350.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4DPJS@85009|Propionibacteriales	201174|Actinobacteria	KT	PspA/IM30 family	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158390_k127_4047066_10	67315.JOBD01000013_gene6984	1.72e-29	120.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4047066_4	28444.JODQ01000001_gene2312	2.682e-103	346.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4EGS5@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158390_k127_4047066_5	68570.DC74_4281	5.157e-76	258.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4053896_0	382464.ABSI01000010_gene3557	1.214e-107	357.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_4053896_1	1519464.HY22_13440	1.111e-83	282.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
SRR25158390_k127_4053896_2	794903.OPIT5_22580	0.000408	43.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
SRR25158390_k127_4054980_6	1120950.KB892749_gene3303	5.706e-11	64.0	COG0681@1|root,COG0681@2|Bacteria,2I3M4@201174|Actinobacteria,4DSA2@85009|Propionibacteriales	201174|Actinobacteria	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158390_k127_4054980_2	110319.CF8_1395	9.036e-68	232.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4DQX0@85009|Propionibacteriales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158390_k127_4054980_1	1123320.KB889737_gene5367	6.837e-97	328.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158390_k127_4054980_4	1048339.KB913029_gene3300	1.769e-42	157.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4ET35@85013|Frankiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_4054980_3	235985.BBPN01000016_gene5887	2.201e-65	233.0	COG1210@1|root,COG1210@2|Bacteria,2GQCI@201174|Actinobacteria	201174|Actinobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR25158390_k127_4054980_0	443255.SCLAV_4099	9.917e-188	601.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR25158390_k127_4054980_5	1033730.CAHG01000012_gene2308	7.072e-19	96.0	2DM3D@1|root,31J5I@2|Bacteria,2I578@201174|Actinobacteria,4DWXX@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
SRR25158390_k127_4072634_8	105420.BBPO01000004_gene1404	1.186e-64	226.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,2NJJS@228398|Streptacidiphilus	201174|Actinobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158390_k127_4072634_2	391037.Sare_2646	2.474e-186	594.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4DIA2@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
SRR25158390_k127_4072634_1	1429046.RR21198_5368	3.215e-222	702.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4FWT0@85025|Nocardiaceae	201174|Actinobacteria	L	tRNA-splicing ligase RtcB	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158390_k127_4072634_10	1306406.ASHX01000001_gene1880	4.285e-37	146.0	COG1371@1|root,COG1371@2|Bacteria,2IS0V@201174|Actinobacteria	201174|Actinobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158390_k127_4072634_11	656024.FsymDg_2714	7.741e-08	57.0	2B44D@1|root,31WUW@2|Bacteria,2GXYK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4072634_7	65497.JODV01000026_gene1841	4.14e-69	247.0	COG2390@1|root,COG2390@2|Bacteria,2GMIM@201174|Actinobacteria,4E3CG@85010|Pseudonocardiales	201174|Actinobacteria	K	Putative sugar-binding domain	-	-	-	ko:K11531	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sugar-bind
SRR25158390_k127_4072634_0	882083.SacmaDRAFT_4651	2.507e-226	708.0	COG1653@1|root,COG1653@2|Bacteria,2GNI2@201174|Actinobacteria,4DYB3@85010|Pseudonocardiales	201174|Actinobacteria	G	ABC-type sugar transport system, periplasmic component	smoE	-	-	ko:K02027,ko:K10227	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	SBP_bac_1
SRR25158390_k127_4072634_4	882083.SacmaDRAFT_4650	2.214e-142	458.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4DZMV@85010|Pseudonocardiales	201174|Actinobacteria	G	Permease component of ABC-type sugar transporter	smoF	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
SRR25158390_k127_4072634_5	882083.SacmaDRAFT_4649	1.073e-135	438.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,4DYNA@85010|Pseudonocardiales	201174|Actinobacteria	G	ABC-type sugar transport system, permease component	smoG	-	-	ko:K10229	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	BPD_transp_1
SRR25158390_k127_4072634_3	66373.JOFQ01000006_gene3088	3.626e-151	483.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158390_k127_4072634_9	479435.Kfla_6395	3.196e-49	190.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria,4DVBA@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_4072634_6	1157637.KB892102_gene1477	3.528e-116	386.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_4086947_0	1048339.KB913029_gene4683	6.274e-227	713.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4ESAT@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158390_k127_4086947_2	526227.Mesil_3163	6.609e-46	174.0	COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158390_k127_4086947_1	994479.GL877878_gene2546	1.074e-102	345.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4DZTC@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158390_k127_4086947_4	1146883.BLASA_2035	1.437e-10	66.0	2EHMB@1|root,33BD3@2|Bacteria,2HU2A@201174|Actinobacteria,4EWKK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4086947_3	1380346.JNIH01000025_gene4707	2.378e-11	66.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria	201174|Actinobacteria	E	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158390_k127_4088677_0	1463881.KL591002_gene4303	1.316e-131	421.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria	201174|Actinobacteria	E	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158390_k127_4088677_3	1380347.JNII01000005_gene3545	1.666e-49	187.0	COG2138@1|root,COG2138@2|Bacteria,2GNJ0@201174|Actinobacteria,4ETDK@85013|Frankiales	201174|Actinobacteria	S	CbiX	sirB	-	-	-	-	-	-	-	-	-	-	-	CbiX
SRR25158390_k127_4088677_6	1068978.AMETH_3830	5.376e-12	66.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria,4E7KV@85010|Pseudonocardiales	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158390_k127_4088677_5	1206737.BAGF01000060_gene4012	5.15e-17	82.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria,4G31F@85025|Nocardiaceae	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158390_k127_4088677_1	1120950.KB892760_gene5759	8.421e-106	357.0	COG1171@1|root,COG1171@2|Bacteria,2GKCC@201174|Actinobacteria,4DQ9J@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_4088677_2	1206732.BAGD01000046_gene1609	7.322e-100	341.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4G3BS@85025|Nocardiaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_409050_8	926564.KI911765_gene4616	4.767e-56	202.0	COG4405@1|root,COG4405@2|Bacteria,2IKQP@201174|Actinobacteria,4F4M3@85017|Promicromonosporaceae	201174|Actinobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158390_k127_409050_0	1120950.KB892830_gene5048	3.101e-230	721.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GNDC@201174|Actinobacteria,4DN4P@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase GMP reductase	guaB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_409050_4	1122182.KB903838_gene4101	1.576e-113	373.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4DB6R@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158390_k127_409050_3	1122182.KB903838_gene4100	1.257e-140	454.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D8FF@85008|Micromonosporales	201174|Actinobacteria	V	Daunorubicin resistance abc transporter atpase subunit	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
SRR25158390_k127_409050_7	263358.VAB18032_12460	3.805e-64	226.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4DDP0@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_409050_2	40571.JOEA01000018_gene7949	1.783e-162	524.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DXRB@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158390_k127_409050_1	1121385.AQXW01000004_gene1580	1.338e-216	678.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,1ZVN0@145357|Dermacoccaceae	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158390_k127_409050_6	1464048.JNZS01000007_gene4476	5.064e-79	271.0	COG2021@1|root,COG2021@2|Bacteria,2I36C@201174|Actinobacteria,4DCQN@85008|Micromonosporales	201174|Actinobacteria	E	Serine aminopeptidase, S33	pcaD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158390_k127_409050_5	1298863.AUEP01000005_gene2652	1.183e-91	310.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4DNRI@85009|Propionibacteriales	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158390_k127_409050_9	1123065.ATWL01000002_gene1591	8.041e-24	102.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158390_k127_4094164_2	709986.Deima_1286	5.788e-13	69.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_4094164_0	1304865.JAGF01000001_gene1114	5.204e-53	207.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_4094164_1	570268.ANBB01000047_gene3998	5.251e-38	147.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158390_k127_4098803_1	1463864.JOGO01000003_gene2012	5.871e-35	135.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158390_k127_4098803_0	1968.JOEV01000046_gene2329	0.0	1480.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria	201174|Actinobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158390_k127_4104984_2	1123023.JIAI01000008_gene1511	7.031e-54	191.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria,4E3H8@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_4104984_0	1120950.KB892786_gene113	7.46e-227	707.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DN3F@85009|Propionibacteriales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_4104984_1	1120960.ATXG01000004_gene1813	2.113e-77	266.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,4FP3U@85023|Microbacteriaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_4112165_20	1121926.AXWO01000013_gene2178	2.274e-08	59.0	COG1653@1|root,COG1653@2|Bacteria,2HF1Z@201174|Actinobacteria,4F080@85014|Glycomycetales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	-
SRR25158390_k127_4112165_3	749414.SBI_00813	4.469e-165	525.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_4112165_4	1121924.ATWH01000020_gene3267	2.516e-123	401.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4FS78@85023|Microbacteriaceae	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_4112165_19	1445613.JALM01000094_gene3791	1.653e-09	64.0	COG4954@1|root,COG4954@2|Bacteria,2IFBK@201174|Actinobacteria,4E3QH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2000
SRR25158390_k127_4112165_12	383372.Rcas_3189	3.324e-62	225.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158390_k127_4112165_6	219305.MCAG_00727	8.431e-100	333.0	COG1670@1|root,COG1670@2|Bacteria,2IIYT@201174|Actinobacteria,4DIGB@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158390_k127_4112165_14	1121946.AUAX01000007_gene3041	1.155e-47	175.0	2B8SK@1|root,3222I@2|Bacteria,2H6AX@201174|Actinobacteria,4DJPG@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4112165_18	1449346.JQMO01000003_gene5418	2.139e-19	93.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria,2M3TQ@2063|Kitasatospora	201174|Actinobacteria	S	Fic/DOC family	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158390_k127_4112165_13	1502851.FG93_01103	2.064e-55	199.0	COG0346@1|root,COG0346@2|Bacteria,1RG38@1224|Proteobacteria,2U5KA@28211|Alphaproteobacteria,3JY96@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158390_k127_4112165_0	1380386.JIAW01000004_gene361	5.383e-249	793.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,2371U@1762|Mycobacteriaceae	201174|Actinobacteria	G	PTS system fructose IIA component	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr
SRR25158390_k127_4112165_9	1123023.JIAI01000002_gene4895	1.067e-75	263.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4E2P5@85010|Pseudonocardiales	201174|Actinobacteria	S	Dihydroxyacetone kinase	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158390_k127_4112165_2	477641.MODMU_5201	1.54e-178	563.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4EU6G@85013|Frankiales	201174|Actinobacteria	G	PFAM Dak kinase	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
SRR25158390_k127_4112165_8	1206732.BAGD01000068_gene2658	2.25e-88	298.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4G6KA@85025|Nocardiaceae	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158390_k127_4112165_17	1206741.BAFX01000010_gene6828	5.511e-23	110.0	COG1414@1|root,COG1414@2|Bacteria,2GJAZ@201174|Actinobacteria,4G6CN@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	gylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4112165_15	1032480.MLP_33760	1.04e-41	158.0	COG3832@1|root,COG3832@2|Bacteria,2I4FM@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158390_k127_4112165_5	1120950.KB892776_gene793	5.508e-104	346.0	COG2021@1|root,COG2021@2|Bacteria,2GIZI@201174|Actinobacteria,4DVIS@85009|Propionibacteriales	201174|Actinobacteria	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_4112165_10	471853.Bcav_3956	8.437e-71	250.0	COG2334@1|root,COG2334@2|Bacteria,2GZQZ@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_4112165_11	1464048.JNZS01000007_gene4362	2.721e-62	231.0	2DZEW@1|root,32V8X@2|Bacteria,2IMS3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4112165_1	219305.MCAG_05484	1.693e-205	642.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DCY7@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_4112165_16	1120960.ATXG01000003_gene1994	3.995e-30	128.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_4112165_7	1121946.AUAX01000025_gene6387	1.586e-98	324.0	COG0406@1|root,COG0406@2|Bacteria,2GKY6@201174|Actinobacteria,4DEY8@85008|Micromonosporales	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158390_k127_4121515_2	1120950.KB892755_gene5915	2.513e-58	216.0	COG2334@1|root,COG2334@2|Bacteria,2GQU8@201174|Actinobacteria,4DW7K@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_4121515_0	1289387.AUKW01000019_gene598	9.692e-255	796.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria	201174|Actinobacteria	EG	Belongs to the ILVD EDD family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
SRR25158390_k127_4121515_3	1123065.ATWL01000014_gene3452	2.667e-53	197.0	COG2186@1|root,COG2186@2|Bacteria,2I91R@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158390_k127_4121515_1	484770.UFO1_0930	1.099e-93	323.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,4H53C@909932|Negativicutes	909932|Negativicutes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1
SRR25158390_k127_4121515_4	1414720.CBYM010000024_gene2106	1.233e-15	81.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,36F3B@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
SRR25158390_k127_4135971_1	1089544.KB912942_gene1881	9.782e-248	790.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DXVG@85010|Pseudonocardiales	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	kojP	-	2.4.1.230	ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158390_k127_4135971_7	1386089.N865_09675	3.555e-83	283.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria,4FGIY@85021|Intrasporangiaceae	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4135971_0	351607.Acel_0801	0.0	1319.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4ERQZ@85013|Frankiales	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158390_k127_4135971_13	44060.JODL01000015_gene5237	1.88e-43	163.0	COG5502@1|root,COG5502@2|Bacteria,2ISMP@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158390_k127_4135971_18	864051.BurJ1DRAFT_4547	8.307e-07	55.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
SRR25158390_k127_4135971_8	1120950.KB892757_gene6512	7.556e-72	258.0	COG1503@1|root,COG1503@2|Bacteria,2I8DT@201174|Actinobacteria	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4135971_17	351607.Acel_0976	3.832e-11	69.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4ERR6@85013|Frankiales	201174|Actinobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_4135971_21	1123320.KB889675_gene3907	5.166e-05	50.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_4135971_20	754252.PFREUD_12830	4.859e-05	54.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4135971_5	2002.JOEQ01000066_gene7859	6.306e-132	434.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4EKR6@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA1	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_4135971_15	101510.RHA1_ro05383	3.093e-36	146.0	2DUIA@1|root,32W6H@2|Bacteria,2I80Q@201174|Actinobacteria,4G2RJ@85025|Nocardiaceae	201174|Actinobacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
SRR25158390_k127_4135971_3	1463879.JOHP01000008_gene367	4.892e-179	569.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158390_k127_4135971_4	2002.JOEQ01000017_gene7760	2.331e-173	550.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4EQIQ@85012|Streptosporangiales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_4135971_19	1214101.BN159_0268	3.261e-05	50.0	2B0YB@1|root,31TBE@2|Bacteria,2GS35@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4135971_12	1179773.BN6_56290	2.623e-45	175.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_4135971_2	869210.Marky_1642	6.007e-216	679.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158390_k127_4135971_9	1122138.AQUZ01000019_gene8187	2.535e-64	228.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158390_k127_4135971_14	1122138.AQUZ01000019_gene8187	2.788e-43	172.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158390_k127_4135971_16	1394178.AWOO02000021_gene7353	1.056e-29	126.0	COG4309@1|root,COG4309@2|Bacteria,2GS7C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
SRR25158390_k127_4135971_11	479432.Sros_4571	5.422e-59	208.0	2BVHN@1|root,332R2@2|Bacteria,2IPM7@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158390_k127_4135971_6	390989.JOEG01000001_gene4974	1.169e-86	292.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria,4DFSP@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR
SRR25158390_k127_4135971_10	1463926.JOCA01000025_gene6928	4.547e-60	211.0	COG3945@1|root,COG3945@2|Bacteria,2IK6G@201174|Actinobacteria	201174|Actinobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_4138812_6	266117.Rxyl_0363	1.014e-60	220.0	COG0683@1|root,COG0683@2|Bacteria,2I8ME@201174|Actinobacteria,4CQWB@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158390_k127_4138812_4	266117.Rxyl_0364	1.215e-80	276.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4138812_5	266117.Rxyl_0366	1.615e-78	275.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CQ9A@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158390_k127_4138812_3	266117.Rxyl_0367	3.075e-109	359.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4CTCZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_4138812_2	266117.Rxyl_0357	3.139e-131	439.0	COG2079@1|root,COG2079@2|Bacteria,2I8CW@201174|Actinobacteria,4CT8P@84995|Rubrobacteria	84995|Rubrobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158390_k127_4138812_8	266117.Rxyl_0356	1.68e-54	201.0	COG4126@1|root,COG4126@2|Bacteria,2INMJ@201174|Actinobacteria	201174|Actinobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4138812_1	1463857.JOFZ01000006_gene3571	3.311e-133	447.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
SRR25158390_k127_4138812_11	994479.GL877879_gene4776	1.909e-24	110.0	COG4829@1|root,COG4829@2|Bacteria,2IQZJ@201174|Actinobacteria,4E6B0@85010|Pseudonocardiales	201174|Actinobacteria	Q	Muconolactone delta-isomerase	catC	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
SRR25158390_k127_4138812_0	2002.JOEQ01000036_gene624	8.589e-233	728.0	COG0044@1|root,COG0044@2|Bacteria,2GKEC@201174|Actinobacteria,4EMQV@85012|Streptosporangiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158390_k127_4138812_10	471852.Tcur_2630	4.888e-36	143.0	2CR5C@1|root,32SNF@2|Bacteria,2IT0H@201174|Actinobacteria,4EJMI@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158390_k127_4138812_7	29306.JOBE01000013_gene6262	6.647e-58	214.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	JD73_05665	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158390_k127_4138812_9	469371.Tbis_3304	1.749e-54	198.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4EAVY@85010|Pseudonocardiales	201174|Actinobacteria	G	Trehalose-phosphatase	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158390_k127_4174425_2	644283.Micau_0224	5.313e-28	121.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4DEVR@85008|Micromonosporales	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_4174425_1	1123320.KB889702_gene9457	2.571e-65	233.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4174425_0	928724.SacglDRAFT_03203	2.167e-165	541.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4DYKG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	vdh	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.23	ko:K00271	ko00280,ko01100,ko01110,ko01130,map00280,map01100,map01110,map01130	-	R01212,R01434	RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_4174425_3	680198.SCAB_47871	0.0002336	46.0	2EGRW@1|root,33AI2@2|Bacteria,2IQF3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
SRR25158390_k127_4207139_2	211114.JOEF01000016_gene3618	1.078e-103	345.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria,4E24R@85010|Pseudonocardiales	201174|Actinobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158390_k127_4207139_0	1133850.SHJG_8450	2.148e-309	972.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158390_k127_4207139_5	1156844.KB891831_gene4501	4.156e-91	323.0	COG0673@1|root,COG0673@2|Bacteria,2I102@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158390_k127_4207139_4	1416759.AYMR01000006_gene1308	3.576e-94	319.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4FKSP@85023|Microbacteriaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158390_k127_4207139_10	1210045.ALNP01000001_gene3287	9.566e-70	243.0	COG4912@1|root,COG4912@2|Bacteria,2ID3C@201174|Actinobacteria	201174|Actinobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158390_k127_4207139_9	1996.JOFO01000042_gene5102	8.548e-71	247.0	COG1670@1|root,COG1670@2|Bacteria,2IFMK@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57,2.3.1.82	ko:K00657,ko:K00663	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_8
SRR25158390_k127_4207139_3	1206739.BAGJ01000252_gene4689	8.723e-98	330.0	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria,4FU92@85025|Nocardiaceae	201174|Actinobacteria	K	COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158390_k127_4207139_8	1206739.BAGJ01000252_gene4688	8.307e-72	248.0	COG1713@1|root,COG1713@2|Bacteria	2|Bacteria	H	HD superfamily hydrolase involved in NAD metabolism	nadD	-	2.7.6.3,2.7.7.18	ko:K00950,ko:K00969,ko:K06950	ko00760,ko00790,ko01100,map00760,map00790,map01100	M00115,M00126,M00841	R00137,R03005,R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
SRR25158390_k127_4207139_11	1122138.AQUZ01000005_gene2670	6.363e-47	173.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4DWJ9@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4207139_6	1463841.JOIR01000045_gene1982	1.693e-85	284.0	COG3467@1|root,COG3467@2|Bacteria,2IAMC@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_4207139_7	405948.SACE_6259	2.139e-77	259.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria,4E2TW@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_4207139_1	1120950.KB892746_gene3457	3.309e-212	666.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DP3H@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_4238814_2	1449353.JQMQ01000005_gene2063	4.253e-154	491.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,2NEZ8@228398|Streptacidiphilus	201174|Actinobacteria	J	tRNA synthetases class I (E and Q), catalytic domain	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
SRR25158390_k127_4238814_3	585531.HMPREF0063_11226	1.865e-113	371.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4DPHV@85009|Propionibacteriales	201174|Actinobacteria	Q	Domain of unknown function (DUF2437)	fahA	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158390_k127_4238814_4	1120948.KB903244_gene3092	9.648e-20	94.0	COG5416@1|root,COG5416@2|Bacteria,2GQTQ@201174|Actinobacteria,4E6KF@85010|Pseudonocardiales	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR25158390_k127_4238814_0	1120950.KB892741_gene2682	7.984e-263	818.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4DNDJ@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158390_k127_4238814_1	1120950.KB892741_gene2679	3.138e-171	543.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4DPRZ@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158390_k127_4238814_5	471853.Bcav_1417	3.79e-10	63.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158390_k127_4239340_4	1120950.KB892823_gene553	3.056e-27	119.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4DQZ7@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_4239340_1	1121926.AXWO01000002_gene1654	1.715e-83	286.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,4EYG7@85014|Glycomycetales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158390_k127_4239340_3	408672.NBCG_02464	6.888e-33	138.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4DQZ7@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_4239340_6	1449347.JQLN01000005_gene3804	1.11e-12	75.0	2EID2@1|root,33C4E@2|Bacteria,2IG1H@201174|Actinobacteria,2M3AU@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF4245)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4245
SRR25158390_k127_4239340_5	1906.SFRA_32195	1.202e-23	102.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158390_k127_4239340_0	1120950.KB892823_gene550	4.263e-150	484.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4DNJ0@85009|Propionibacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158390_k127_4239340_2	1179773.BN6_08140	2.059e-64	224.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DX3Z@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158390_k127_4241392_2	1120950.KB892823_gene462	8.481e-90	303.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,4DQN5@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_4241392_7	105420.BBPO01000014_gene6106	1.04e-10	72.0	COG3103@1|root,COG4991@2|Bacteria,2GQYX@201174|Actinobacteria,2NJXJ@228398|Streptacidiphilus	201174|Actinobacteria	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158390_k127_4241392_0	1120950.KB892823_gene460	6.408e-193	613.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNNT@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158390_k127_4241392_3	1120950.KB892823_gene459	3.268e-87	299.0	COG3396@1|root,COG3396@2|Bacteria,2GKXZ@201174|Actinobacteria,4DMYE@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
SRR25158390_k127_4241392_6	298654.FraEuI1c_0748	7.799e-21	95.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria,4ETF4@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158390_k127_4241392_4	1288083.AUKR01000013_gene734	8.932e-78	265.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_4241392_5	1463864.JOGO01000073_gene1214	1.132e-56	212.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158390_k127_4241392_1	1449353.JQMQ01000005_gene2352	1.474e-148	473.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,2NH5M@228398|Streptacidiphilus	201174|Actinobacteria	HP	ThiF family	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158390_k127_426199_9	656024.FsymDg_0067	1.382e-14	75.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4ETQ4@85013|Frankiales	201174|Actinobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,DUF234
SRR25158390_k127_426199_0	479435.Kfla_4889	6.052e-308	949.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DNV7@85009|Propionibacteriales	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158390_k127_426199_3	1121019.AUMN01000011_gene3448	1.601e-149	486.0	COG3292@1|root,COG3292@2|Bacteria,2I5U5@201174|Actinobacteria	201174|Actinobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_426199_6	28444.JODQ01000017_gene6564	4.014e-98	334.0	COG4552@1|root,COG4552@2|Bacteria,2HW68@201174|Actinobacteria,4EFHU@85012|Streptosporangiales	201174|Actinobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158390_k127_426199_5	1120950.KB892741_gene2668	7.925e-110	363.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DNYY@85009|Propionibacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_426199_7	743718.Isova_2798	2.857e-70	263.0	COG0308@1|root,COG0308@2|Bacteria,2ID1N@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_426199_4	1048339.KB913029_gene3458	1.276e-115	384.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4ES6J@85013|Frankiales	201174|Actinobacteria	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158390_k127_426199_1	479432.Sros_8137	1.608e-190	605.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158390_k127_426199_2	1048339.KB913029_gene4285	5.129e-184	594.0	COG0392@1|root,COG1215@1|root,COG0392@2|Bacteria,COG1215@2|Bacteria,2I3M7@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_426199_8	1227484.C471_10876	1.451e-37	147.0	COG3839@1|root,arCOG00177@2157|Archaea,2XTFK@28890|Euryarchaeota,23S9H@183963|Halobacteria	183963|Halobacteria	E	COG3842 ABC-type spermidine putrescine transport systems, ATPase components	sfuC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158390_k127_4270430_1	67356.KL575607_gene8843	5.31e-106	353.0	COG2141@1|root,COG2141@2|Bacteria,2I9BN@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4270430_0	512565.AMIS_25380	3.207e-126	410.0	28KEA@1|root,2ZA0J@2|Bacteria,2I9YN@201174|Actinobacteria,4DCRZ@85008|Micromonosporales	201174|Actinobacteria	H	Sulfotransferase domain	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
SRR25158390_k127_4278210_5	58123.JOFJ01000015_gene4474	1.692e-51	186.0	COG4262@1|root,COG4262@2|Bacteria,2GK41@201174|Actinobacteria,4EHG0@85012|Streptosporangiales	201174|Actinobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158390_k127_4278210_1	55952.BU52_19670	4.132e-174	556.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158390_k127_4278210_2	1223523.H340_27071	7.471e-145	472.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_4278210_3	35754.JNYJ01000029_gene9515	2.517e-85	301.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4DBAU@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158390_k127_4278210_0	66377.JOBH01000009_gene4994	4.135e-214	681.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158390_k127_4278210_6	1193181.BN10_1140020	9.673e-36	137.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4FHA9@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158390_k127_4278210_4	68194.JNXR01000028_gene2156	2.134e-62	218.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158390_k127_4279764_1	1463903.JOIZ01000015_gene2185	3.85e-53	198.0	COG2186@1|root,COG3265@1|root,COG2186@2|Bacteria,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria	201174|Actinobacteria	G	gluconokinase	gntK	-	2.7.1.12,2.7.1.71,3.2.1.52	ko:K00851,ko:K00891,ko:K01207	ko00030,ko00400,ko00520,ko00531,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01501,map00030,map00400,map00520,map00531,map01100,map01110,map01120,map01130,map01200,map01230,map01501	M00022,M00628	R00022,R01737,R02412,R05963,R07809,R07810,R10831	RC00002,RC00017,RC00049,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,SKI
SRR25158390_k127_4279764_0	134676.ACPL_1948	3.297e-56	214.0	COG3265@1|root,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria,4DEYC@85008|Micromonosporales	201174|Actinobacteria	G	Shikimate kinase	gntK	-	2.7.1.12,2.7.1.71,3.2.1.52	ko:K00851,ko:K00891,ko:K01207	ko00030,ko00400,ko00520,ko00531,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01501,map00030,map00400,map00520,map00531,map01100,map01110,map01120,map01130,map01200,map01230,map01501	M00022,M00628	R00022,R01737,R02412,R05963,R07809,R07810,R10831	RC00002,RC00017,RC00049,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,SKI
SRR25158390_k127_4286979_3	263358.VAB18032_25015	4.585e-09	63.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4DI6E@85008|Micromonosporales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158390_k127_4286979_0	1095767.CAHD01000130_gene1287	6.208e-77	274.0	COG1404@1|root,COG1404@2|Bacteria,2GNIX@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158390_k127_4286979_1	1089545.KB913037_gene661	3.376e-64	230.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4E333@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158390_k127_4286979_2	345341.KUTG_04400	1.119e-35	140.0	2E61P@1|root,330QX@2|Bacteria,2II66@201174|Actinobacteria,4E5U0@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4293946_19	979556.MTES_3620	8.293e-09	61.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FNJ1@85023|Microbacteriaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_4293946_7	996637.SGM_1399	1.669e-69	246.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_4293946_17	219305.MCAG_04555	6.968e-15	78.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4293946_16	1122611.KB903939_gene548	2.454e-15	83.0	COG0316@1|root,COG0316@2|Bacteria,2GR0Z@201174|Actinobacteria,4EKHC@85012|Streptosporangiales	201174|Actinobacteria	S	HesB YadR YfhF-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158390_k127_4293946_0	446468.Ndas_0017	4.489e-259	811.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,4EH3P@85012|Streptosporangiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_4293946_8	1120950.KB892749_gene3304	9.374e-66	226.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4DQX0@85009|Propionibacteriales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158390_k127_4293946_11	1123284.KB899042_gene1435	9.437e-46	171.0	COG2124@1|root,COG2124@2|Bacteria,1TP02@1239|Firmicutes,4HAIY@91061|Bacilli	91061|Bacilli	Q	Cytochrome P450	cypC	-	1.11.2.4	ko:K15629	-	-	R09740	-	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_4293946_10	690850.Desaf_1336	5.607e-57	205.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42VMP@68525|delta/epsilon subdivisions,2WS6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome P450	-	-	1.11.2.4	ko:K15629	-	-	R09740	-	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_4293946_1	66377.JOBH01000001_gene1637	6.914e-181	578.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_4293946_3	1380347.JNII01000006_gene1106	2.461e-117	393.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,4ES4W@85013|Frankiales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR25158390_k127_4293946_5	44060.JODL01000013_gene3842	1.566e-95	326.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_4293946_18	1370121.AUWS01000068_gene39	3.951e-10	68.0	2AY59@1|root,31Q77@2|Bacteria,2HSBY@201174|Actinobacteria,23BDJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4293946_13	1463881.KL591008_gene1891	1.566e-30	128.0	COG0517@1|root,COG0517@2|Bacteria,2I36Y@201174|Actinobacteria	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_4293946_2	882083.SacmaDRAFT_1092	7.341e-143	462.0	COG4221@1|root,COG4221@2|Bacteria,2I2YS@201174|Actinobacteria,4E1HG@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_4293946_15	1317118.ATO8_20789	2.199e-19	92.0	COG0838@1|root,COG0838@2|Bacteria,1PPP2@1224|Proteobacteria,2U7SM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q4
SRR25158390_k127_4293946_6	1146883.BLASA_1946	3.706e-73	262.0	28NMB@1|root,32VZ3@2|Bacteria,2I631@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4293946_4	494419.ALPM01000058_gene2914	3.291e-117	385.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,1WAI0@1268|Micrococcaceae	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158390_k127_4293946_9	494419.ALPM01000058_gene2913	1.194e-64	239.0	COG0839@1|root,COG0839@2|Bacteria,2IBCM@201174|Actinobacteria,1WAXG@1268|Micrococcaceae	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q3
SRR25158390_k127_4293946_12	477641.MODMU_1625	7.812e-39	149.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158390_k127_4293946_14	526225.Gobs_1701	3.083e-25	115.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4ES6W@85013|Frankiales	201174|Actinobacteria	CP	NADH-quinone oxidoreductase chain L	-	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158390_k127_4299793_0	479432.Sros_4836	1.085e-290	906.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4EGHW@85012|Streptosporangiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158390_k127_4299793_3	208439.AJAP_38765	7.267e-44	171.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria,4E5MD@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR
SRR25158390_k127_4299793_2	1179773.BN6_59760	1.311e-83	285.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4E2XH@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158390_k127_4299793_1	1120950.KB892747_gene3669	4.445e-186	589.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4DN1Z@85009|Propionibacteriales	201174|Actinobacteria	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_4300591_9	1380354.JIAN01000006_gene638	6.606e-11	64.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4F0HX@85016|Cellulomonadaceae	201174|Actinobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SRR25158390_k127_4300591_5	653045.Strvi_2375	3.237e-91	306.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158390_k127_4300591_8	1298880.AUEV01000014_gene3620	2.71e-11	66.0	COG3677@1|root,COG3677@2|Bacteria,2GQKE@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4300591_1	1120950.KB892708_gene4213	3.776e-274	852.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4DP25@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158390_k127_4300591_2	1298863.AUEP01000018_gene3905	4.423e-213	674.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DN98@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158390_k127_4300591_10	1121926.AXWO01000002_gene1453	6.807e-07	54.0	2BPEB@1|root,32I6H@2|Bacteria,2HBYD@201174|Actinobacteria,4F07M@85014|Glycomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4300591_7	1089455.MOPEL_135_02010	4.971e-18	87.0	2DRKZ@1|root,33C8D@2|Bacteria,2HSV5@201174|Actinobacteria,4F7B1@85018|Dermatophilaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4300591_3	443218.AS9A_4444	4.475e-183	586.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2I8V5@201174|Actinobacteria,234RP@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158390_k127_4300591_6	471853.Bcav_0348	5.422e-61	213.0	COG0454@1|root,COG0456@2|Bacteria,2I32H@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_4300591_4	269800.Tfu_1385	1.05e-135	441.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EG7I@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_4300591_0	1298880.AUEV01000007_gene4616	3.14e-310	975.0	COG1061@1|root,COG1061@2|Bacteria,2GNGE@201174|Actinobacteria	201174|Actinobacteria	KL	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
SRR25158390_k127_4307671_2	1869.MB27_06395	3.989e-71	243.0	COG1917@1|root,COG1917@2|Bacteria,2IIQD@201174|Actinobacteria,4DF71@85008|Micromonosporales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_4307671_7	298655.KI912266_gene680	8.741e-06	49.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4ES0N@85013|Frankiales	201174|Actinobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_4307671_5	1068980.ARVW01000001_gene1323	2.138e-50	189.0	2EB1T@1|root,3352K@2|Bacteria,2IR9P@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158390_k127_4307671_0	1449976.KALB_1825	1.452e-141	456.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DXVD@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	GO:0001101,GO:0001666,GO:0006950,GO:0008150,GO:0009415,GO:0009628,GO:0010035,GO:0036293,GO:0042221,GO:0050896,GO:0070482,GO:1901700	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2,SnoaL_4
SRR25158390_k127_4307671_4	1123319.AUBE01000001_gene1851	2.636e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4307671_3	570268.ANBB01000045_gene1186	3.886e-56	199.0	COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria,4EPSM@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_4307671_1	1122138.AQUZ01000019_gene8187	4.998e-119	396.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158390_k127_4308639_1	457429.ABJI02000741_gene292	1.609e-155	500.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158390_k127_4308639_0	266940.Krad_3364	1.048e-173	553.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria	201174|Actinobacteria	F	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158390_k127_4308639_2	1122138.AQUZ01000002_gene2188	2.158e-31	126.0	COG3764@1|root,COG3764@2|Bacteria,2IRXZ@201174|Actinobacteria,4DRSR@85009|Propionibacteriales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158390_k127_4327737_25	455632.SGR_4134	2.413e-34	137.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4184J@629295|Streptomyces griseus group	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_4327737_9	66875.JODY01000045_gene2727	3.562e-115	382.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158390_k127_4327737_21	1246995.AFR_33830	4.727e-82	279.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR25158390_k127_4327737_6	1122611.KB903939_gene451	8.1e-130	421.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4EHJ0@85012|Streptosporangiales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158390_k127_4327737_12	1120950.KB892801_gene1753	1.149e-108	357.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria,4DP80@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4327737_2	43354.JOIJ01000007_gene1631	8.887e-182	579.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DZGZ@85010|Pseudonocardiales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158390_k127_4327737_3	1120950.KB892801_gene1748	1.634e-160	513.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4DNMZ@85009|Propionibacteriales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158390_k127_4327737_7	1122933.JNIY01000003_gene363	4.665e-123	405.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,4F1T3@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158390_k127_4327737_10	253839.SSNG_03112	2.485e-113	372.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria	201174|Actinobacteria	L	adenine glycosylase	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158390_k127_4327737_23	1089455.MOPEL_099_00510	1.029e-63	221.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4F6UZ@85018|Dermatophilaceae	201174|Actinobacteria	I	B12 binding domain	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158390_k127_4327737_24	1137269.AZWL01000011_gene3129	3.517e-39	158.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158390_k127_4327737_26	743718.Isova_0883	1.537e-14	78.0	COG0666@1|root,COG0666@2|Bacteria,2I3AT@201174|Actinobacteria,4F52A@85017|Promicromonosporaceae	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158390_k127_4327737_5	1068980.ARVW01000001_gene7443	3.142e-145	464.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_4327737_1	1120936.KB907208_gene770	4.19e-232	733.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4EHBU@85012|Streptosporangiales	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158390_k127_4327737_17	521096.Tpau_3231	1.058e-89	308.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158390_k127_4327737_8	1236902.ANAS01000020_gene1769	4.966e-123	399.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4EH1C@85012|Streptosporangiales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158390_k127_4327737_18	408672.NBCG_04679	4.93e-89	306.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DMZZ@85009|Propionibacteriales	201174|Actinobacteria	M	G5	rlpA	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158390_k127_4327737_16	1033730.CAHG01000012_gene1969	3.588e-91	308.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4DPJ5@85009|Propionibacteriales	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158390_k127_4327737_0	1306174.JODP01000001_gene4899	1.956e-321	992.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158390_k127_4327737_19	585531.HMPREF0063_12436	6.06e-88	301.0	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4DQCH@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158390_k127_4327737_11	1449353.JQMQ01000005_gene2591	6.669e-113	371.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,2NEIU@228398|Streptacidiphilus	201174|Actinobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158390_k127_4327737_4	1896.JOAU01000015_gene2152	4.808e-146	481.0	COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria	201174|Actinobacteria	O	PFAM glycosyl transferase family 39	pmt	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
SRR25158390_k127_4327737_13	67373.JOBF01000027_gene1642	1.256e-105	349.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_4327737_14	512565.AMIS_55900	5.645e-105	355.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4D8MG@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158390_k127_4327737_15	1157634.KB912943_gene4197	5.192e-103	348.0	COG2377@1|root,COG2377@2|Bacteria,2GNAM@201174|Actinobacteria	201174|Actinobacteria	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SRR25158390_k127_4327737_20	1463881.KL591006_gene2373	6.083e-84	287.0	COG2103@1|root,COG2103@2|Bacteria,2GN0K@201174|Actinobacteria	201174|Actinobacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158390_k127_4327737_22	29540.C481_01687	2.09e-79	275.0	COG1874@1|root,arCOG04085@2157|Archaea,2XSU6@28890|Euryarchaeota,23UX4@183963|Halobacteria	183963|Halobacteria	G	COG1874 Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4329074_2	1068980.ARVW01000001_gene858	5.649e-154	498.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8,Oxidored_FMN
SRR25158390_k127_4329074_1	479432.Sros_6948	3.489e-210	665.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria,4EMVZ@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_4329074_4	208439.AJAP_30710	2.321e-135	435.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158390_k127_4329074_6	1120934.KB894435_gene4464	6.463e-44	179.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria,4E4CQ@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_4329074_3	469383.Cwoe_2160	3.676e-140	454.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria,4CSG2@84995|Rubrobacteria	84995|Rubrobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4329074_5	58344.JOEL01000099_gene6787	1.167e-57	220.0	COG0454@1|root,COG0456@2|Bacteria,2IFM6@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_4329074_0	196162.Noca_3266	1.321e-222	701.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DNUI@85009|Propionibacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158390_k127_4333905_3	935839.JAGJ01000010_gene339	1.16e-23	103.0	COG1292@1|root,COG1292@2|Bacteria,2GJX0@201174|Actinobacteria,4F34H@85017|Promicromonosporaceae	201174|Actinobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
SRR25158390_k127_4333905_1	263358.VAB18032_20530	1.005e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4D9QK@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_4333905_0	1120960.ATXG01000014_gene547	8.48e-124	403.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria,4FMDR@85023|Microbacteriaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158390_k127_4333905_2	1122622.ATWJ01000008_gene2849	8.41e-25	107.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria,4FG98@85021|Intrasporangiaceae	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_4344073_0	28042.GU90_04150	1.851e-183	584.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158390_k127_4344073_1	1095767.CAHD01000068_gene3061	2.066e-65	228.0	COG2606@1|root,COG2606@2|Bacteria,2IIIW@201174|Actinobacteria,4F1D0@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158390_k127_4344073_2	1120950.KB892776_gene793	4.973e-11	68.0	COG2021@1|root,COG2021@2|Bacteria,2GIZI@201174|Actinobacteria,4DVIS@85009|Propionibacteriales	201174|Actinobacteria	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_4355010_7	1109445.AGSX01000015_gene1932	1.019e-22	100.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1S3FE@1236|Gammaproteobacteria,1YZU9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158390_k127_4355010_1	1123023.JIAI01000012_gene9230	7.717e-96	322.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4DY81@85010|Pseudonocardiales	201174|Actinobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
SRR25158390_k127_4355010_2	1380356.JNIK01000013_gene4257	1.646e-95	331.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4ETTQ@85013|Frankiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI2	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158390_k127_4355010_6	1123320.KB889675_gene3872	5.799e-27	121.0	2CGM3@1|root,32S47@2|Bacteria,2GP7H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4355010_0	58123.JOFJ01000005_gene1487	3.118e-96	324.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria,4EQYV@85012|Streptosporangiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158390_k127_4355010_4	1122933.JNIY01000003_gene484	3.578e-62	225.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4F17T@85016|Cellulomonadaceae	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158390_k127_4355010_8	1206725.BAFU01000027_gene2671	1.321e-19	94.0	2E65S@1|root,330UF@2|Bacteria,2IMEQ@201174|Actinobacteria,4G26C@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
SRR25158390_k127_4355010_5	479432.Sros_9301	1.853e-32	136.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4EHHN@85012|Streptosporangiales	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158390_k127_4355010_9	1120950.KB892764_gene5613	6.564e-16	87.0	COG1622@1|root,COG1622@2|Bacteria,2GS05@201174|Actinobacteria,4DSJB@85009|Propionibacteriales	201174|Actinobacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158390_k127_4355010_3	1120950.KB892708_gene4217	3.002e-95	321.0	arCOG02771@1|root,2Z93M@2|Bacteria,2I3TS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4363816_10	2045.KR76_03095	2.247e-45	177.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4DPBR@85009|Propionibacteriales	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158390_k127_4363816_6	1120950.KB892762_gene5484	2.253e-75	263.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4DQJF@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_4363816_1	1120950.KB892762_gene5486	2.751e-118	383.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DNJN@85009|Propionibacteriales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158390_k127_4363816_2	1122609.AUGT01000011_gene3507	1.224e-104	344.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4DMXW@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_4363816_12	42256.RradSPS_2385	3.446e-14	78.0	2CEID@1|root,34BIU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4363816_0	1121019.AUMN01000020_gene1693	5.17e-240	755.0	COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria,1W8N6@1268|Micrococcaceae	201174|Actinobacteria	T	Carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158390_k127_4363816_9	1146883.BLASA_1989	2.015e-54	200.0	2CZII@1|root,32T6G@2|Bacteria,2IK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4363816_4	369723.Strop_4347	6.152e-84	288.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4D9MK@85008|Micromonosporales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_4363816_3	1120950.KB892762_gene5491	1.304e-85	291.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4DQHA@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_4363816_8	1298863.AUEP01000015_gene1790	1.104e-59	213.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4DQIS@85009|Propionibacteriales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158390_k127_4363816_11	1121367.AQXC01000009_gene246	3.323e-26	108.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,22P69@1653|Corynebacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158390_k127_4363816_7	1122182.KB903837_gene3733	8.858e-61	220.0	COG1522@1|root,COG1522@2|Bacteria,2HVG9@201174|Actinobacteria,4DDPB@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_4363816_5	1122182.KB903837_gene3734	2.95e-78	267.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4DAGA@85008|Micromonosporales	201174|Actinobacteria	C	dehydrogenase, E1 component	pdhA2	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158390_k127_4383381_14	1122609.AUGT01000012_gene4241	1.016e-14	77.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria,4DS7D@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4383381_10	479435.Kfla_2798	5.507e-87	320.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria,4DQFZ@85009|Propionibacteriales	201174|Actinobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158390_k127_4383381_2	1120950.KB892707_gene4807	7.468e-214	695.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4DNVQ@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III, epsilon subunit	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158390_k127_4383381_15	58344.JOEL01000002_gene1740	6.953e-12	76.0	2EP6A@1|root,33GT0@2|Bacteria,2GQTX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4383381_3	1288083.AUKR01000001_gene1180	6.443e-135	438.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158390_k127_4383381_12	1122138.AQUZ01000033_gene3622	1.508e-56	201.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4DQR3@85009|Propionibacteriales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158390_k127_4383381_6	110319.CF8_2761	4.576e-94	314.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4DNEE@85009|Propionibacteriales	201174|Actinobacteria	C	cytochrome c oxidase subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158390_k127_4383381_7	1463936.JOJI01000017_gene7528	2.327e-90	310.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158390_k127_4383381_4	1122138.AQUZ01000033_gene3626	2.99e-113	380.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4DNGA@85009|Propionibacteriales	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158390_k127_4383381_1	479435.Kfla_2786	1.117e-220	706.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4DNCY@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome b	qcrB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158390_k127_4383381_8	351607.Acel_2091	1.27e-89	305.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4ESEQ@85013|Frankiales	201174|Actinobacteria	EG	EamA-like transporter family	cyeA	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_4383381_11	1122609.AUGT01000008_gene2914	3.213e-86	295.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4DQKR@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158390_k127_4383381_13	1120950.KB892707_gene4796	1.621e-49	182.0	2D9MJ@1|root,32TTI@2|Bacteria,2IFFM@201174|Actinobacteria,4DQZG@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
SRR25158390_k127_4383381_0	110319.CF8_2767	1.736e-280	872.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4DPQI@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158390_k127_4383381_9	1032480.MLP_42040	3.639e-87	298.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4DNSR@85009|Propionibacteriales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158390_k127_4383381_5	58123.JOFJ01000001_gene3184	8.546e-99	329.0	COG1104@1|root,COG1104@2|Bacteria,2GJ2B@201174|Actinobacteria,4EHSY@85012|Streptosporangiales	201174|Actinobacteria	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,TusA
SRR25158390_k127_4389507_21	1122622.ATWJ01000010_gene1288	4.171e-13	72.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4FEEE@85021|Intrasporangiaceae	201174|Actinobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158390_k127_4389507_5	1380356.JNIK01000019_gene405	7.047e-118	395.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4ERVW@85013|Frankiales	201174|Actinobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158390_k127_4389507_3	1048339.KB913029_gene3762	2.862e-133	430.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4ERZB@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158390_k127_4389507_16	1240349.ANGC01000009_gene2690	2.236e-54	198.0	2DZHZ@1|root,32VB7@2|Bacteria,2GPY2@201174|Actinobacteria,4FYYG@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4389507_13	1179773.BN6_24180	4.538e-66	244.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,4E4AD@85010|Pseudonocardiales	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SRR25158390_k127_4389507_4	405948.SACE_2001	1.738e-125	416.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4E1TE@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	fprA	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_4389507_9	710696.Intca_3208	9.336e-92	312.0	COG0697@1|root,COG0697@2|Bacteria,2I9T9@201174|Actinobacteria,4FFPR@85021|Intrasporangiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_4389507_15	68170.KL590493_gene6389	2.071e-56	217.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_4389507_17	1120934.KB894410_gene6939	2.735e-49	182.0	COG0454@1|root,COG0456@2|Bacteria,2I2E3@201174|Actinobacteria,4E5CK@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_4389507_10	1869.MB27_31245	1.301e-79	291.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria,4DB8R@85008|Micromonosporales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide
SRR25158390_k127_4389507_8	1043205.AFYF01000061_gene2831	2.623e-97	344.0	COG0477@1|root,COG0477@2|Bacteria,2IIAH@201174|Actinobacteria,4FK06@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158390_k127_4389507_6	1304865.JAGF01000001_gene3755	4.116e-108	359.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158390_k127_4389507_11	1304865.JAGF01000001_gene3756	9.401e-71	248.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158390_k127_4389507_2	1304865.JAGF01000001_gene3757	1.183e-146	469.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158390_k127_4389507_20	1120950.KB892756_gene6693	1.251e-21	96.0	2AU8K@1|root,31JVT@2|Bacteria,2HZCZ@201174|Actinobacteria,4DS5N@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
SRR25158390_k127_4389507_0	1048339.KB913029_gene3595	0.0	2067.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4ES42@85013|Frankiales	201174|Actinobacteria	L	DEAD DEAH box helicase domain protein	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158390_k127_4389507_14	1122138.AQUZ01000042_gene3360	7.525e-64	230.0	COG5340@1|root,COG5340@2|Bacteria,2II40@201174|Actinobacteria,4DR8H@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_4389507_7	263358.VAB18032_10935	1.225e-107	361.0	COG1940@1|root,COG1940@2|Bacteria,2GJ3W@201174|Actinobacteria,4DAV0@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,ROK
SRR25158390_k127_4389507_19	1449347.JQLN01000005_gene3362	2.112e-30	125.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,2M314@2063|Kitasatospora	201174|Actinobacteria	K	Helix-turn-helix	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158390_k127_4389507_18	479435.Kfla_2995	4.161e-38	155.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4DRIW@85009|Propionibacteriales	201174|Actinobacteria	S	Competence-damaged protein	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158390_k127_4389507_12	479435.Kfla_2994	1.936e-70	243.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4DQPW@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_4389507_1	110319.CF8_2448	1.259e-155	500.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4DNHY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158390_k127_440094_7	446466.Cfla_1546	1.425e-28	117.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4F1C3@85016|Cellulomonadaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158390_k127_440094_1	590998.Celf_1568	5.908e-182	573.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4F0Z7@85016|Cellulomonadaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158390_k127_440094_0	1416759.AYMR01000006_gene1183	1.414e-186	591.0	COG4992@1|root,COG4992@2|Bacteria,2GK0J@201174|Actinobacteria,4FKQF@85023|Microbacteriaceae	201174|Actinobacteria	E	Aminotransferase class-III	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_440094_3	378806.STAUR_2095	6.899e-57	205.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2X9UF@28221|Deltaproteobacteria,2YV67@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158390_k127_440094_5	479431.Namu_3223	6.556e-40	156.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158390_k127_440094_4	526227.Mesil_0060	2.402e-56	205.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_440094_2	926560.KE387023_gene2479	7.368e-114	378.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158390_k127_440094_6	1123322.KB904697_gene4671	7.609e-35	136.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_4409995_8	1068978.AMETH_4905	1.016e-104	348.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4E0S7@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158390_k127_4409995_14	1121272.KB903252_gene1192	8.243e-35	139.0	COG1413@1|root,COG1413@2|Bacteria,2IRUS@201174|Actinobacteria,4DF7W@85008|Micromonosporales	201174|Actinobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2
SRR25158390_k127_4409995_0	479433.Caci_0809	2.231e-285	885.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158390_k127_4409995_12	479435.Kfla_1417	6.771e-48	176.0	COG0789@1|root,COG0789@2|Bacteria,2IMV1@201174|Actinobacteria,4DUXA@85009|Propionibacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158390_k127_4409995_10	1120950.KB892708_gene4505	2.212e-92	312.0	COG0791@1|root,COG0791@2|Bacteria,2IFT3@201174|Actinobacteria,4DRZD@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	NLPC_P60
SRR25158390_k127_4409995_6	479435.Kfla_1418	7.431e-197	619.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DNK5@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4409995_1	479435.Kfla_1419	5.406e-274	851.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DTHF@85009|Propionibacteriales	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158390_k127_4409995_7	471853.Bcav_3740	1.14e-183	589.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158390_k127_4409995_11	446471.Xcel_1013	1.925e-77	265.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4F437@85017|Promicromonosporaceae	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
SRR25158390_k127_4409995_5	1120950.KB892759_gene6228	2.823e-202	647.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DPPG@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158390_k127_4409995_16	1120950.KB892759_gene6230	5.082e-15	76.0	2DSSU@1|root,33HAR@2|Bacteria,2GWP2@201174|Actinobacteria,4DSRX@85009|Propionibacteriales	201174|Actinobacteria	S	Acyl-CoA carboxylase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_epsilon
SRR25158390_k127_4409995_13	196162.Noca_2334	1.003e-42	162.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria,4DPMS@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158390_k127_4409995_3	1313172.YM304_21920	1.846e-207	664.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4CNRU@84992|Acidimicrobiia	84992|Acidimicrobiia	EU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158390_k127_4409995_9	1172179.AUKV01000003_gene7489	3.193e-94	331.0	2E8R3@1|root,33322@2|Bacteria,2I97P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4409995_4	471852.Tcur_3608	4.462e-205	655.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4EHD6@85012|Streptosporangiales	201174|Actinobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158390_k127_4409995_2	1440053.JOEI01000005_gene1980	2.296e-271	848.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria	201174|Actinobacteria	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158390_k127_4409995_15	1110697.NCAST_32_10580	2.395e-16	79.0	COG3576@1|root,COG3576@2|Bacteria,2GKCF@201174|Actinobacteria,4FY1G@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_4419373_0	1122609.AUGT01000006_gene1497	2.156e-99	339.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158390_k127_4419373_7	1122609.AUGT01000006_gene1498	3.404e-21	104.0	COG2155@1|root,COG2155@2|Bacteria,2H8ZK@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF378)	-	-	-	-	-	-	-	-	-	-	-	-	DUF378
SRR25158390_k127_4419373_5	269800.Tfu_2993	2.591e-29	124.0	COG0711@1|root,COG0711@2|Bacteria,2IQQZ@201174|Actinobacteria,4EKQP@85012|Streptosporangiales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4419373_1	44060.JODL01000031_gene1764	5.366e-45	173.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158390_k127_4419373_2	1306406.ASHX01000002_gene5199	1.124e-41	164.0	2B9CE@1|root,2ZB7A@2|Bacteria,2I2DB@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158390_k127_4419373_12	234267.Acid_1030	0.0006314	45.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,3Y3SH@57723|Acidobacteria	57723|Acidobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158390_k127_4419373_11	1172179.AUKV01000004_gene6710	3.347e-09	62.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158390_k127_4419373_9	1156844.KB891842_gene7412	1.049e-10	64.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158390_k127_4419373_3	1120948.KB903218_gene1718	3.866e-38	147.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria,4E7I2@85010|Pseudonocardiales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_4419373_8	298654.FraEuI1c_1909	8.96e-21	94.0	2DR8X@1|root,33AQM@2|Bacteria,2GXTC@201174|Actinobacteria,4EWM3@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4419373_10	1246445.ANAY01000012_gene12	1.388e-10	64.0	COG2337@1|root,COG2337@2|Bacteria,2GS6G@201174|Actinobacteria	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
SRR25158390_k127_4419373_4	1172188.KB911820_gene3085	3.242e-35	144.0	28RB9@1|root,2ZDQU@2|Bacteria,2GZQK@201174|Actinobacteria,4FIZG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4419373_6	1120950.KB892772_gene1119	2.116e-24	110.0	2BB4Q@1|root,324M3@2|Bacteria,2H9HU@201174|Actinobacteria,4DWEJ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4424158_0	1463900.JOIX01000006_gene775	9.674e-272	848.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158390_k127_4424158_1	479432.Sros_0566	1.361e-180	576.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4EI7A@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158390_k127_4424158_3	1435356.Y013_24705	5.827e-39	151.0	COG0317@1|root,COG0317@2|Bacteria,2HVAA@201174|Actinobacteria,4G8C5@85025|Nocardiaceae	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4424158_2	479435.Kfla_4612	3.008e-97	334.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158390_k127_4426008_11	996637.SGM_5752	1.252e-28	116.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158390_k127_4426008_7	1463936.JOJI01000017_gene7502	5.94e-93	310.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158390_k127_4426008_9	644283.Micau_3331	3.051e-50	182.0	COG0824@1|root,COG0824@2|Bacteria,2II60@201174|Actinobacteria,4DE50@85008|Micromonosporales	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158390_k127_4426008_0	1121939.L861_19415	6.034e-193	611.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1SFAR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_4426008_4	1079986.JH164861_gene7150	1.129e-147	486.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_4426008_5	263358.VAB18032_17730	2.048e-143	469.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4DBE1@85008|Micromonosporales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_4426008_1	263358.VAB18032_17735	1.781e-191	608.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DB5K@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_4426008_8	1894.JOER01000008_gene600	2.222e-80	273.0	COG1309@1|root,COG1309@2|Bacteria,2GNBI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158390_k127_4426008_2	263358.VAB18032_17750	1.389e-186	592.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4D934@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_4426008_3	1155714.KB891993_gene5692	4.187e-185	597.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_4426008_6	29306.JOBE01000001_gene2539	5.535e-93	313.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	HSD17B	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158390_k127_4426008_10	397278.JOJN01000002_gene100	1.373e-47	171.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DN1G@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158390_k127_4441984_8	1463845.JOIG01000002_gene2283	1.305e-13	71.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158390_k127_4441984_1	1120950.KB892744_gene2775	3.45e-192	612.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria,4DP01@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_4441984_3	1120950.KB892744_gene2774	8.913e-131	430.0	COG1175@1|root,COG1175@2|Bacteria,2GKYS@201174|Actinobacteria,4DP26@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158390_k127_4441984_2	590998.Celf_3599	2.341e-140	458.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4F0UW@85016|Cellulomonadaceae	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158390_k127_4441984_0	1298863.AUEP01000002_gene1501	7.647e-280	874.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DPPX@85009|Propionibacteriales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158390_k127_4441984_6	1122138.AQUZ01000051_gene7585	1.095e-42	158.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4DRND@85009|Propionibacteriales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158390_k127_4441984_5	1463887.KL590039_gene5783	1.917e-49	181.0	COG0748@1|root,COG0748@2|Bacteria,2I36B@201174|Actinobacteria	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_4441984_4	1123024.AUII01000025_gene2112	8.646e-68	241.0	COG1174@1|root,COG1174@2|Bacteria,2GMQT@201174|Actinobacteria,4DXYP@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system, permease component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158390_k127_4441984_7	1121019.AUMN01000001_gene782	1.047e-25	107.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,1W80J@1268|Micrococcaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158390_k127_4443549_5	1120950.KB892823_gene505	3.066e-80	271.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4DNDN@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158390_k127_4443549_6	397278.JOJN01000006_gene1020	4.299e-78	269.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4DPM7@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158390_k127_4443549_1	436229.JOEH01000016_gene7262	1.01e-148	479.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,2NEAY@228398|Streptacidiphilus	201174|Actinobacteria	E	Peptidase family M28	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158390_k127_4443549_2	469371.Tbis_2652	1.587e-133	431.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4DYHD@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
SRR25158390_k127_4443549_3	1048339.KB913029_gene27	5.545e-105	349.0	COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,2GKXN@201174|Actinobacteria,4EXF5@85013|Frankiales	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4443549_4	570268.ANBB01000001_gene1298	2.049e-98	331.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4EJR7@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4443549_9	1394178.AWOO02000079_gene2153	4.331e-28	119.0	COG1277@1|root,COG1277@2|Bacteria,2GJ2R@201174|Actinobacteria,4EITH@85012|Streptosporangiales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158390_k127_4443549_10	1123320.KB889680_gene2647	1.235e-19	89.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HisKA_3,Response_reg
SRR25158390_k127_4443549_0	1120936.KB907208_gene1057	9.263e-151	490.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4EGV1@85012|Streptosporangiales	201174|Actinobacteria	E	Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158390_k127_4443549_8	479435.Kfla_5524	5.527e-62	214.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4DR37@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_4443549_7	1435356.Y013_14200	1.88e-67	241.0	COG0454@1|root,COG0456@2|Bacteria,2H5WU@201174|Actinobacteria,4FUVF@85025|Nocardiaceae	201174|Actinobacteria	K	FR47-like protein	-	-	2.3.1.1	ko:K22476	ko00220,ko01210,ko01230,map00220,map01210,map01230	-	R00259	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
SRR25158390_k127_4447180_24	227882.SAV_6110	1.129e-39	158.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria	201174|Actinobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158390_k127_4447180_13	1120950.KB892707_gene4878	4.113e-124	422.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4DNDP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158390_k127_4447180_9	1120950.KB892707_gene4879	6.788e-144	464.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DNSG@85009|Propionibacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158390_k127_4447180_17	479435.Kfla_2877	2.941e-67	231.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4DQJP@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158390_k127_4447180_11	1463881.KL591002_gene4482	2.015e-134	436.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria	201174|Actinobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158390_k127_4447180_29	1155718.KB891854_gene2884	5.249e-12	72.0	COG2919@1|root,COG2919@2|Bacteria,2I3SE@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158390_k127_4447180_10	1048339.KB913029_gene4582	8.175e-136	469.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4ERN7@85013|Frankiales	201174|Actinobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158390_k127_4447180_6	266940.Krad_3204	1.782e-156	514.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria	201174|Actinobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_4447180_8	1172179.AUKV01000019_gene2858	1.233e-149	488.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0008150,GO:0040007	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_4447180_5	367299.JOEE01000004_gene1359	9.429e-158	503.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4FEX5@85021|Intrasporangiaceae	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158390_k127_4447180_2	1120950.KB892707_gene4888	1.054e-194	620.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4DNTV@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_4447180_14	479435.Kfla_2886	1.82e-122	409.0	COG0707@1|root,COG0772@1|root,COG0707@2|Bacteria,COG0772@2|Bacteria,2GJEM@201174|Actinobacteria,4DN0T@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158390_k127_4447180_12	284031.JNXD01000001_gene5649	3.682e-132	432.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158390_k127_4447180_3	1122138.AQUZ01000010_gene5212	1.505e-189	604.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4DNNN@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158390_k127_4447180_25	477641.MODMU_3453	3.03e-31	133.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4ETEJ@85013|Frankiales	201174|Actinobacteria	M	Essential cell division protein	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158390_k127_4447180_4	196162.Noca_3060	5.347e-176	561.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4DND0@85009|Propionibacteriales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158390_k127_4447180_15	653045.Strvi_7162	9.649e-79	271.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158390_k127_4447180_16	1120950.KB892707_gene4894	2.825e-76	265.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4DQBA@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158390_k127_4447180_18	1120950.KB892707_gene4895	3.812e-56	201.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4DR13@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158390_k127_4447180_20	1906.SFRA_02190	2.23e-51	185.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158390_k127_4447180_26	1312959.KI914655_gene731	4.069e-28	116.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,1WA3V@1268|Micrococcaceae	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158390_k127_4447180_22	1120950.KB892707_gene4897	4.374e-44	173.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4DQHF@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division initiation protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158390_k127_4447180_1	1123322.KB904652_gene570	0.0	1529.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158390_k127_4447180_27	593907.Celgi_0935	1.59e-23	102.0	COG1872@1|root,COG1872@2|Bacteria,2GQSC@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158390_k127_4447180_21	58344.JOEL01000004_gene7047	1.51e-45	172.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158390_k127_4447180_23	36809.MAB_2700c	1.168e-40	160.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,233CS@1762|Mycobacteriaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158390_k127_4447180_7	1169161.KB897723_gene4826	1.584e-154	493.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158390_k127_4447180_19	2002.JOEQ01000006_gene1291	4.401e-56	210.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,2IJ0D@201174|Actinobacteria,4EJRB@85012|Streptosporangiales	201174|Actinobacteria	E	Chorismate mutase type II	-	-	-	-	-	-	-	-	-	-	-	-	CM_2,DAHP_synth_1
SRR25158390_k127_4447180_28	1137271.AZUM01000001_gene620	7.201e-20	95.0	2EFXK@1|root,339PU@2|Bacteria,2GTIE@201174|Actinobacteria,4E6WJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4447180_0	1032480.MLP_28710	0.0	1702.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DN5X@85009|Propionibacteriales	201174|Actinobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158390_k127_4447212_6	397278.JOJN01000014_gene3593	6.095e-95	311.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DN2F@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	GO:0000988,GO:0000990,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158390_k127_4447212_11	1048339.KB913029_gene1812	8.369e-05	49.0	2DREV@1|root,33BF4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4447212_10	656024.FsymDg_4044	8.218e-27	117.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria,4EWYP@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_4447212_1	258052.JNYV01000008_gene3517	3.938e-194	629.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,2M05F@2063|Kitasatospora	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	CarboxypepD_reg,MMPL
SRR25158390_k127_4447212_5	1121926.AXWO01000001_gene3369	2.135e-132	436.0	COG3876@1|root,COG3876@2|Bacteria,2GP1S@201174|Actinobacteria,4EZIM@85014|Glycomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158390_k127_4447212_3	1298880.AUEV01000001_gene5649	1.183e-165	549.0	COG1680@1|root,COG1680@2|Bacteria,2GJQG@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Exo_endo_phos,Peptidase_M6
SRR25158390_k127_4447212_4	1463821.JOGR01000018_gene1222	6.145e-152	491.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4EZ8V@85014|Glycomycetales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158390_k127_4447212_9	441769.ABFU01000068_gene2024	7.608e-32	138.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,1ZRKY@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
SRR25158390_k127_4447212_7	1048339.KB913029_gene3800	7.919e-80	270.0	COG1225@1|root,COG1225@2|Bacteria,2II4M@201174|Actinobacteria	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158390_k127_4447212_2	1120950.KB892708_gene4184	5.507e-184	607.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,4DQ2P@85009|Propionibacteriales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158390_k127_4447212_0	479435.Kfla_3189	5.449e-235	736.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4DP14@85009|Propionibacteriales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158390_k127_4447212_8	208444.JNYY01000003_gene1960	7.43e-76	281.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,4DYPH@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SRR25158390_k127_4447678_10	208439.AJAP_24540	1.312e-55	196.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4DX7E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR25158390_k127_4447678_12	263358.VAB18032_18475	1.782e-17	84.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,4DGHU@85008|Micromonosporales	201174|Actinobacteria	M	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158390_k127_4447678_7	1068978.AMETH_4213	3.038e-81	280.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4447678_0	1146883.BLASA_2610	3.42e-167	533.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4EW71@85013|Frankiales	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158390_k127_4447678_4	333138.LQ50_10385	2.666e-114	382.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4HE36@91061|Bacilli,1ZEH6@1386|Bacillus	91061|Bacilli	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158390_k127_4447678_13	501479.ACNW01000071_gene1249	6.242e-17	89.0	COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2UFJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
SRR25158390_k127_4447678_9	1123239.KB898631_gene2344	7.77e-73	260.0	COG1638@1|root,COG1638@2|Bacteria,1UY2X@1239|Firmicutes,4HCVD@91061|Bacilli	91061|Bacilli	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
SRR25158390_k127_4447678_6	1304865.JAGF01000001_gene412	3.234e-98	332.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4447678_11	1137268.AZXF01000006_gene2040	1.387e-48	184.0	COG0599@1|root,COG2021@1|root,COG0599@2|Bacteria,COG2021@2|Bacteria,2GITB@201174|Actinobacteria,4EIFT@85012|Streptosporangiales	201174|Actinobacteria	E	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
SRR25158390_k127_4447678_5	263358.VAB18032_19735	1.792e-101	346.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DA3U@85008|Micromonosporales	201174|Actinobacteria	F	Adenylosuccinate lyase C-terminus	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158390_k127_4447678_8	219305.MCAG_00689	2.122e-74	256.0	COG3485@1|root,COG3485@2|Bacteria,2GZGT@201174|Actinobacteria,4DEHF@85008|Micromonosporales	201174|Actinobacteria	Q	Dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158390_k127_4447678_2	882083.SacmaDRAFT_1742	2.984e-122	395.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4DZ5N@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase, beta	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRR25158390_k127_4447678_3	356851.JOAN01000002_gene739	1.272e-117	389.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DB71@85008|Micromonosporales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158390_k127_4447678_1	287986.DV20_15225	1.14e-137	441.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4DXHC@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	gctA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158390_k127_4449824_14	1206743.BAGM01000113_gene3249	4.708e-05	53.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4FVZ0@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158390_k127_4449824_0	1157640.AQWO01000009_gene736	0.0	1144.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158390_k127_4449824_5	743718.Isova_0854	4.317e-114	379.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4F5HG@85017|Promicromonosporaceae	201174|Actinobacteria	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158390_k127_4449824_4	287986.DV20_43445	3.518e-115	388.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E086@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_4449824_10	446471.Xcel_2672	9.707e-69	242.0	COG4760@1|root,COG4760@2|Bacteria,2GNCK@201174|Actinobacteria,4F3Q9@85017|Promicromonosporaceae	201174|Actinobacteria	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
SRR25158390_k127_4449824_8	479433.Caci_8032	3.664e-80	287.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158390_k127_4449824_12	1074488.AGBX01000001_gene920	4.05e-31	131.0	COG0351@1|root,COG0819@1|root,COG0351@2|Bacteria,COG0819@2|Bacteria,2GKZM@201174|Actinobacteria,4FCIE@85020|Dermabacteraceae	201174|Actinobacteria	HK	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TENA_THI-4,TMP-TENI
SRR25158390_k127_4449824_3	1463855.JOHV01000002_gene2437	8.651e-119	386.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158390_k127_4449824_13	1996.JOFO01000003_gene6349	1.908e-14	79.0	COG2104@1|root,COG2104@2|Bacteria,2GQKM@201174|Actinobacteria,4EKQA@85012|Streptosporangiales	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_4449824_2	1343740.M271_35820	2.331e-129	424.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158390_k127_4449824_7	58123.JOFJ01000001_gene3130	1.633e-87	297.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4EFN3@85012|Streptosporangiales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
SRR25158390_k127_4449824_11	1120950.KB892752_gene6190	1.576e-33	130.0	2E5A7@1|root,3302F@2|Bacteria,2IQ7Z@201174|Actinobacteria,4DVUC@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158390_k127_4449824_6	471852.Tcur_1047	1.685e-93	317.0	COG2755@1|root,COG2755@2|Bacteria,2GMVS@201174|Actinobacteria,4EFQN@85012|Streptosporangiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158390_k127_4449824_1	103733.JNYO01000012_gene2803	3.555e-234	730.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2GIXE@201174|Actinobacteria,4E0ZQ@85010|Pseudonocardiales	201174|Actinobacteria	EK	Cystathionine beta-synthase	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158390_k127_4449824_9	1276920.ADIAG_00366	6.781e-74	254.0	COG1695@1|root,COG1695@2|Bacteria,2I997@201174|Actinobacteria,1W9ET@1268|Micrococcaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_4450828_1	1123023.JIAI01000007_gene1962	1.942e-203	640.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158390_k127_4450828_0	1445613.JALM01000036_gene2873	0.0	1341.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E1F5@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158390_k127_4450828_4	446470.Snas_1823	2.446e-81	294.0	COG2086@1|root,COG2086@2|Bacteria,2IB9F@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158390_k127_4450828_5	1445613.JALM01000036_gene2875	2.825e-80	291.0	COG2025@1|root,COG2025@2|Bacteria,2I9CI@201174|Actinobacteria,4E0Z1@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
SRR25158390_k127_4450828_3	446470.Snas_1825	3.548e-87	296.0	COG1414@1|root,COG1414@2|Bacteria,2GJAZ@201174|Actinobacteria,4EYX2@85014|Glycomycetales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4450828_6	1151119.KB895497_gene3322	2.011e-42	164.0	COG1309@1|root,COG1309@2|Bacteria,2IKK0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_4450828_8	1125863.JAFN01000001_gene2355	1.587e-23	117.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4450828_9	189753.AXAS01000028_gene8112	4.408e-15	80.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TVQF@28211|Alphaproteobacteria,3JXF2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
SRR25158390_k127_4450828_10	1122611.KB903940_gene1692	9.009e-06	59.0	COG0500@1|root,COG2226@2|Bacteria,2IM1I@201174|Actinobacteria,4ENT2@85012|Streptosporangiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_4450828_2	479434.Sthe_2247	1.91e-160	537.0	COG2909@1|root,COG2909@2|Bacteria,2G80F@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_4452898_5	391937.NA2_06952	5.92e-64	229.0	COG0834@1|root,COG0834@2|Bacteria,1R26Z@1224|Proteobacteria,2VEUM@28211|Alphaproteobacteria,43KE2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158390_k127_4452898_2	1121019.AUMN01000010_gene2009	6.225e-130	426.0	COG0006@1|root,COG0006@2|Bacteria,2HT32@201174|Actinobacteria,1W8QP@1268|Micrococcaceae	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_4452898_1	1121019.AUMN01000010_gene2010	4.397e-154	498.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158390_k127_4452898_0	446470.Snas_1334	5.345e-211	663.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4EZNR@85014|Glycomycetales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_4452898_3	1463825.JNXC01000029_gene424	1.651e-77	261.0	COG2318@1|root,COG2318@2|Bacteria,2IGJQ@201174|Actinobacteria,4E0R8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_4452898_4	1121946.AUAX01000030_gene1283	1.67e-68	237.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4D8J9@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158390_k127_4452898_6	1122138.AQUZ01000094_gene5494	1.706e-56	198.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158390_k127_4452898_7	1122138.AQUZ01000044_gene4500	4.259e-56	199.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DNPQ@85009|Propionibacteriales	201174|Actinobacteria	V	daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_4468274_5	1463934.JOCF01000059_gene3339	1.156e-54	198.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158390_k127_4468274_7	1054860.KB913030_gene2565	4.172e-15	83.0	COG0760@1|root,COG0760@2|Bacteria,2GJDI@201174|Actinobacteria	201174|Actinobacteria	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
SRR25158390_k127_4468274_1	1157637.KB892138_gene2641	8.594e-120	402.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158390_k127_4468274_2	1304865.JAGF01000001_gene1732	2.375e-108	358.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4F1ZX@85016|Cellulomonadaceae	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	dasC	-	-	ko:K02026,ko:K17331	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	BPD_transp_1
SRR25158390_k127_4468274_3	1122609.AUGT01000009_gene2987	1.406e-107	360.0	COG1175@1|root,COG1175@2|Bacteria,2GX5P@201174|Actinobacteria,4DQP0@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17330	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR25158390_k127_4468274_0	1122609.AUGT01000009_gene2986	1.395e-145	475.0	COG1653@1|root,COG1653@2|Bacteria,2GKM8@201174|Actinobacteria,4DQWX@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17329	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_4468274_4	471852.Tcur_0126	4.941e-70	246.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4EFGC@85012|Streptosporangiales	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158390_k127_4468274_6	1385521.N803_09865	5.429e-35	139.0	COG0454@1|root,COG0456@2|Bacteria,2GMPX@201174|Actinobacteria,4FHW6@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158390_k127_4471134_1	1120950.KB892720_gene1920	5.581e-159	509.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4DP4I@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158390_k127_4471134_0	479435.Kfla_5891	3.43e-201	632.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4DP3K@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_4471134_2	561175.KB894093_gene3088	9.904e-17	81.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4EI5B@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
SRR25158390_k127_4472336_0	1120950.KB892762_gene5452	2.462e-266	831.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4DPFE@85009|Propionibacteriales	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158390_k127_4472336_1	47716.JOFH01000015_gene5747	6.236e-53	191.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158390_k127_4478291_1	1056816.JAFQ01000004_gene4976	5.625e-91	306.0	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria,4FY3N@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
SRR25158390_k127_4478291_0	1056816.JAFQ01000004_gene4977	4.968e-102	334.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4FXKH@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_4482483_18	882083.SacmaDRAFT_2615	3.227e-47	178.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EB67@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR25158390_k127_4482483_17	797304.Natgr_0416	2.069e-48	190.0	COG3391@1|root,arCOG02562@2157|Archaea,2XUGN@28890|Euryarchaeota,23TBE@183963|Halobacteria	183963|Halobacteria	S	Cell surface glycoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4482483_10	408672.NBCG_00449	1.636e-85	285.0	COG2193@1|root,COG2193@2|Bacteria,2GJEI@201174|Actinobacteria,4DQDS@85009|Propionibacteriales	201174|Actinobacteria	P	Ferritin-like domain	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158390_k127_4482483_21	1298863.AUEP01000001_gene799	2.792e-12	68.0	COG2906@1|root,COG2906@2|Bacteria,2GYWC@201174|Actinobacteria,4DSWG@85009|Propionibacteriales	201174|Actinobacteria	P	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
SRR25158390_k127_4482483_6	882083.SacmaDRAFT_2552	3.195e-119	389.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4DYIF@85010|Pseudonocardiales	201174|Actinobacteria	S	permease, DMT superfamily	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158390_k127_4482483_15	882083.SacmaDRAFT_2551	4.718e-57	204.0	COG5516@1|root,COG5516@2|Bacteria,2GSKJ@201174|Actinobacteria	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158390_k127_4482483_2	263358.VAB18032_25230	8.802e-211	675.0	COG2936@1|root,COG2936@2|Bacteria,2GJ2K@201174|Actinobacteria,4DC1G@85008|Micromonosporales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
SRR25158390_k127_4482483_7	868131.MSWAN_2165	2.31e-112	376.0	COG2327@1|root,arCOG04826@2157|Archaea	2157|Archaea	S	PFAM Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR25158390_k127_4482483_0	868131.MSWAN_2166	1.571e-267	853.0	COG0451@1|root,COG1022@1|root,arCOG01369@2157|Archaea,arCOG04199@2157|Archaea	2157|Archaea	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,Epimerase,NAD_binding_4
SRR25158390_k127_4482483_20	1131462.DCF50_p2424	5.161e-19	95.0	2DQ4Q@1|root,334QV@2|Bacteria,1VVNN@1239|Firmicutes,2513M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4482483_3	1131462.DCF50_p2423	1.234e-132	440.0	COG2303@1|root,COG2303@2|Bacteria,1V115@1239|Firmicutes,24FDE@186801|Clostridia,263C0@186807|Peptococcaceae	186801|Clostridia	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158390_k127_4482483_16	1151119.KB895490_gene2030	8.555e-52	194.0	COG1309@1|root,COG1309@2|Bacteria,2IR68@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_4482483_12	298655.KI912267_gene7323	2.038e-80	288.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4EU7I@85013|Frankiales	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158390_k127_4482483_1	1464048.JNZS01000007_gene4538	7.249e-213	687.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4DH2H@85008|Micromonosporales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_4482483_4	1464048.JNZS01000007_gene4539	1.647e-127	411.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4DE30@85008|Micromonosporales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_4482483_9	1172185.KB911530_gene3435	1.954e-97	328.0	COG0697@1|root,COG0697@2|Bacteria,2GNSA@201174|Actinobacteria,4FZ72@85025|Nocardiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_4482483_5	258052.JNYV01000002_gene2003	1.534e-123	404.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,2M574@2063|Kitasatospora	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_4482483_13	35754.JNYJ01000009_gene1968	1.948e-61	220.0	COG3361@1|root,COG3361@2|Bacteria,2I6N0@201174|Actinobacteria,4D90S@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	wcoQ	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158390_k127_4482483_8	58123.JOFJ01000015_gene4499	1.174e-102	342.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4EMTW@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158390_k127_4482483_11	397278.JOJN01000003_gene2025	1.997e-80	279.0	COG1597@1|root,COG1597@2|Bacteria,2GNTZ@201174|Actinobacteria,4DQQG@85009|Propionibacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158390_k127_4482483_14	644283.Micau_3633	5.014e-61	219.0	COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria,4DM44@85008|Micromonosporales	201174|Actinobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_4487395_0	1122138.AQUZ01000010_gene5127	1.081e-136	443.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4DNQQ@85009|Propionibacteriales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	paaK	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158390_k127_4487395_1	1157637.KB892124_gene701	1.242e-59	212.0	COG2151@1|root,COG2151@2|Bacteria,2II4H@201174|Actinobacteria	201174|Actinobacteria	L	phenylacetate-CoA oxygenase, PaaJ subunit	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158390_k127_4487395_2	446470.Snas_1240	3.417e-13	69.0	COG3396@1|root,COG3396@2|Bacteria,2GJIU@201174|Actinobacteria	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase, PaaI subunit	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158390_k127_4487555_1	263358.VAB18032_00865	7.372e-229	725.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4DAVU@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SRR25158390_k127_4487555_3	471852.Tcur_2413	4.087e-143	471.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4EFSJ@85012|Streptosporangiales	201174|Actinobacteria	C	BFD-like [2Fe-2S] binding domain	nasC	-	-	ko:K00360	ko00910,ko01120,map00910,map01120	M00531	R00798	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Pyr_redox_2
SRR25158390_k127_4487555_0	58123.JOFJ01000006_gene287	1.964e-295	921.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EIEV@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	nasC	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158390_k127_4487555_2	110319.CF8_3286	8.011e-159	514.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4DN4Y@85009|Propionibacteriales	201174|Actinobacteria	P	Major Facilitator Superfamily	narU	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	iNJ661.Rv0267	MFS_1
SRR25158390_k127_4487555_4	591158.SSMG_07040	5.057e-35	136.0	COG1733@1|root,COG1733@2|Bacteria,2IJCU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_4503100_1	1278078.G419_12041	3.257e-64	233.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4FV28@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158390_k127_4503100_0	1273125.Rrhod_0691	4.329e-99	337.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria,4FW85@85025|Nocardiaceae	201174|Actinobacteria	P	Periplasmic binding protein	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158390_k127_4503100_3	359.CN09_00410	0.0001077	53.0	COG0484@1|root,COG0484@2|Bacteria,1NIA4@1224|Proteobacteria,2UUQR@28211|Alphaproteobacteria,4B9BD@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	molecular chaperone	dnaJ2	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158390_k127_4503100_2	1122138.AQUZ01000033_gene3627	8.846e-15	76.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4DNCY@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome b	qcrB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158390_k127_4513801_21	1245475.ANAE01000127_gene603	3.457e-48	181.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4EH5Y@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158390_k127_4513801_16	66874.JOFS01000036_gene6403	1.71e-73	256.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158390_k127_4513801_2	1232410.KI421419_gene2461	2.348e-206	659.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,42YRA@68525|delta/epsilon subdivisions,2WTWV@28221|Deltaproteobacteria,43T2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
SRR25158390_k127_4513801_20	136273.GY22_11510	3.085e-53	201.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,1W7Z8@1268|Micrococcaceae	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158390_k127_4513801_12	263358.VAB18032_10835	6.842e-93	314.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4DB32@85008|Micromonosporales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158390_k127_4513801_23	1370120.AUWR01000044_gene3935	1.418e-36	142.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,239I5@1762|Mycobacteriaceae	201174|Actinobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_4513801_0	263358.VAB18032_10830	4.4e-323	1004.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,Glyco_hydro_43
SRR25158390_k127_4513801_4	287986.DV20_15225	1.503e-137	441.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4DXHC@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	gctA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158390_k127_4513801_7	219305.MCAG_00691	3.069e-122	403.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DB71@85008|Micromonosporales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158390_k127_4513801_6	263358.VAB18032_19725	5.313e-126	407.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4D92V@85008|Micromonosporales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRR25158390_k127_4513801_13	219305.MCAG_00689	4.795e-87	291.0	COG3485@1|root,COG3485@2|Bacteria,2GZGT@201174|Actinobacteria,4DEHF@85008|Micromonosporales	201174|Actinobacteria	Q	Dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158390_k127_4513801_9	219305.MCAG_00688	1.911e-112	382.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DA3U@85008|Micromonosporales	201174|Actinobacteria	F	Adenylosuccinate lyase C-terminus	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158390_k127_4513801_17	1464048.JNZS01000007_gene4476	1.557e-67	243.0	COG2021@1|root,COG2021@2|Bacteria,2I36C@201174|Actinobacteria,4DCQN@85008|Micromonosporales	201174|Actinobacteria	E	Serine aminopeptidase, S33	pcaD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158390_k127_4513801_19	1179773.BN6_61170	5.757e-55	195.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4E4J2@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
SRR25158390_k127_4513801_10	1449976.KALB_2209	1.013e-104	350.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4DZJ6@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4513801_1	263358.VAB18032_19710	1.565e-214	676.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DBNS@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	xylC	-	1.2.1.28	ko:K00141	ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667	RC00075	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_4513801_15	1123239.KB898631_gene2344	7.769e-76	267.0	COG1638@1|root,COG1638@2|Bacteria,1UY2X@1239|Firmicutes,4HCVD@91061|Bacilli	91061|Bacilli	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
SRR25158390_k127_4513801_25	391589.RGAI101_2394	8.035e-05	51.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
SRR25158390_k127_4513801_8	333138.LQ50_10385	1.1e-119	402.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4HE36@91061|Bacilli,1ZEH6@1386|Bacillus	91061|Bacilli	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158390_k127_4513801_11	290400.Jann_3792	1.974e-96	328.0	28MZG@1|root,2ZB66@2|Bacteria,1R6ZF@1224|Proteobacteria,2U3DX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_4513801_3	1123024.AUII01000002_gene921	3.791e-173	550.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4E1GK@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158390_k127_4513801_5	1380390.JIAT01000009_gene1094	4.096e-127	429.0	COG2040@1|root,COG2264@1|root,COG2040@2|Bacteria,COG2264@2|Bacteria,2HQK7@201174|Actinobacteria,4CS5N@84995|Rubrobacteria	84995|Rubrobacteria	EJ	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA,S-methyl_trans
SRR25158390_k127_4513801_18	469383.Cwoe_4383	6.832e-65	227.0	COG2040@1|root,COG2264@1|root,COG2040@2|Bacteria,COG2264@2|Bacteria,2HQK7@201174|Actinobacteria,4CS5N@84995|Rubrobacteria	84995|Rubrobacteria	EJ	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA,S-methyl_trans
SRR25158390_k127_4513801_14	1068978.AMETH_4213	9.61e-82	280.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158390_k127_4513801_22	1206731.BAGB01000068_gene7110	6.689e-43	156.0	COG3467@1|root,COG3467@2|Bacteria,2IAMC@201174|Actinobacteria,4FVEJ@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_4528962_15	33876.JNXY01000048_gene2417	1.859e-98	359.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D9Z5@85008|Micromonosporales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158390_k127_4528962_4	1003195.SCAT_0357	4.023e-224	705.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158390_k127_4528962_27	1120949.KB903317_gene1724	6.271e-39	155.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4DIVE@85008|Micromonosporales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158390_k127_4528962_7	1048339.KB913029_gene1446	3.069e-164	529.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4ERHW@85013|Frankiales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158390_k127_4528962_0	1120936.KB907210_gene5469	0.0	1671.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4EGY7@85012|Streptosporangiales	201174|Actinobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
SRR25158390_k127_4528962_22	55952.BU52_03500	1.428e-50	188.0	COG3707@1|root,COG3707@2|Bacteria	2|Bacteria	T	response regulator	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,PAS_4,Response_reg
SRR25158390_k127_4528962_8	649831.L083_0542	6.265e-153	494.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4D92I@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158390_k127_4528962_16	743718.Isova_2831	5.712e-98	328.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria,4F3KB@85017|Promicromonosporaceae	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_4528962_19	1386089.N865_20950	6.235e-69	248.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158390_k127_4528962_23	1463920.JOGB01000002_gene3268	1.037e-48	183.0	COG1309@1|root,COG1309@2|Bacteria,2IDJT@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_4528962_10	1122611.KB903945_gene1288	2.041e-118	396.0	arCOG02771@1|root,2Z8A4@2|Bacteria,2GNG0@201174|Actinobacteria,4EGF2@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4528962_2	1463920.JOGB01000002_gene3271	3.308e-249	786.0	COG4677@1|root,COG4677@2|Bacteria,2GNHF@201174|Actinobacteria	201174|Actinobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158390_k127_4528962_25	1123321.KB905817_gene5251	3.762e-42	163.0	COG1075@1|root,COG1075@2|Bacteria,2IAEU@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_4528962_30	134676.ACPL_6328	8.432e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,2HX18@201174|Actinobacteria,4DKY6@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4528962_31	1869.MB27_21950	1.226e-09	70.0	COG3507@1|root,COG3507@2|Bacteria,2GIYA@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SRR25158390_k127_4528962_1	134676.ACPL_561	0.0	1207.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DBKN@85008|Micromonosporales	201174|Actinobacteria	G	hydrolase family 65	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158390_k127_4528962_13	512565.AMIS_4000	6.604e-99	332.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria,4D9YP@85008|Micromonosporales	201174|Actinobacteria	S	Beta-phosphoglucomutase family hydrolase	-	GO:0003674,GO:0003824,GO:0008801,GO:0016853,GO:0016866,GO:0016868	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR25158390_k127_4528962_17	1906.SFRA_14210	8.135e-72	252.0	COG1357@1|root,COG1357@2|Bacteria,2GK0E@201174|Actinobacteria	201174|Actinobacteria	E	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158390_k127_4528962_3	1123322.KB904669_gene3601	1.194e-228	715.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158390_k127_4528962_9	1137269.AZWL01000005_gene2389	8.467e-146	478.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria	201174|Actinobacteria	V	MATE efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158390_k127_4528962_21	1048339.KB913029_gene1600	8.754e-55	195.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4ESST@85013|Frankiales	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158390_k127_4528962_28	1463864.JOGO01000016_gene4552	7.237e-36	141.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158390_k127_4528962_18	196162.Noca_4663	5.143e-69	239.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4DQ95@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158390_k127_4528962_26	1146883.BLASA_5038	6.677e-40	152.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4ET1A@85013|Frankiales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158390_k127_4528962_12	1120950.KB892740_gene2553	1.345e-114	379.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4DN5G@85009|Propionibacteriales	201174|Actinobacteria	L	Xylose isomerase-like TIM barrel	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158390_k127_4528962_24	369723.Strop_0030	8.061e-48	182.0	COG1846@1|root,COG1846@2|Bacteria,2IPBX@201174|Actinobacteria,4DCPX@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_4528962_20	2002.JOEQ01000080_gene1526	7.178e-62	219.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4EIQ8@85012|Streptosporangiales	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158390_k127_4528962_6	110319.CF8_3771	1.709e-170	542.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4DPII@85009|Propionibacteriales	201174|Actinobacteria	V	FemAB family	femX	-	2.3.2.10	ko:K05363,ko:K18354	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	R08779	RC00055,RC00096	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	FemAB
SRR25158390_k127_4528962_14	479435.Kfla_7011	1.793e-98	331.0	COG0787@1|root,COG0787@2|Bacteria,2GJJX@201174|Actinobacteria,4DNS3@85009|Propionibacteriales	201174|Actinobacteria	M	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158390_k127_4528962_11	649831.L083_1461	6.428e-115	383.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4D9SS@85008|Micromonosporales	201174|Actinobacteria	S	n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158390_k127_4528962_29	1121946.AUAX01000019_gene7791	2.822e-33	135.0	COG1714@1|root,COG1714@2|Bacteria,2GZE9@201174|Actinobacteria,4DKF9@85008|Micromonosporales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158390_k127_4528962_5	1343740.M271_06530	4.019e-199	630.0	COG3011@1|root,COG3011@2|Bacteria,2GMSU@201174|Actinobacteria	201174|Actinobacteria	S	Lipase maturation factor	LMF	-	-	-	-	-	-	-	-	-	-	-	LMF1
SRR25158390_k127_4542972_1	1003195.SCAT_4802	1.296e-35	136.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Myo-inositol catabolism IolB domain protein	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158390_k127_4542972_0	33876.JNXY01000016_gene6911	4.074e-291	905.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4D98S@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the TPP enzyme family	iolD	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_4554102_1	266940.Krad_1874	3.614e-75	258.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158390_k127_4554102_0	1048339.KB913029_gene4189	9.877e-175	549.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4ERF9@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158390_k127_4560963_5	1229780.BN381_80027	7.211e-52	200.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,3UWVY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158390_k127_4560963_1	710696.Intca_2410	1.794e-189	597.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4FE3A@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_4560963_2	1123320.KB889698_gene9299	7.484e-136	443.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria	201174|Actinobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158390_k127_4560963_9	1032480.MLP_29930	3.978e-06	51.0	2DTJ3@1|root,33KKU@2|Bacteria,2H11Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4560963_7	1120950.KB892745_gene2919	8.996e-23	107.0	COG3428@1|root,COG3428@2|Bacteria,2IA1C@201174|Actinobacteria,4DR83@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158390_k127_4560963_4	469371.Tbis_0920	3.748e-67	232.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4DXV5@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_4560963_6	525904.Tter_2222	4.076e-47	174.0	COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	iscR	-	2.8.1.7	ko:K04487,ko:K13643	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03000,ko03016,ko03029	-	-	-	Rrf2
SRR25158390_k127_4560963_0	1449346.JQMO01000003_gene3419	3.544e-308	951.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,2M2C2@2063|Kitasatospora	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158390_k127_4560963_3	1306174.JODP01000018_gene4385	1.748e-91	310.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158390_k127_4560963_8	1033736.CAHK01000059_gene416	5.028e-11	72.0	2B4JG@1|root,31XBK@2|Bacteria,2HYX0@201174|Actinobacteria,4FB2Y@85019|Brevibacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4561633_2	1123322.KB904677_gene3122	4.817e-65	227.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158390_k127_4561633_0	66874.JOFS01000036_gene6461	1.943e-122	403.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	attS	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
SRR25158390_k127_4561633_1	1380347.JNII01000005_gene2789	7.664e-91	313.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158390_k127_4561633_3	2074.JNYD01000055_gene2331	1.017e-22	98.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E16G@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_4565184_1	479435.Kfla_2210	5.845e-134	444.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria,4DPRU@85009|Propionibacteriales	201174|Actinobacteria	S	50S ribosome-binding GTPase	PPA1638	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
SRR25158390_k127_4565184_0	1298863.AUEP01000005_gene2682	6.956e-177	572.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria,4DPB6@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158390_k127_4565184_2	1449976.KALB_7269	2.049e-72	248.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria,4DYXA@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158390_k127_4565184_4	1385521.N803_10190	5.792e-68	248.0	COG3550@1|root,COG3550@2|Bacteria,2I2QD@201174|Actinobacteria,4FG8P@85021|Intrasporangiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_4565184_3	882082.SaccyDRAFT_0324	1.278e-68	237.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4E2QX@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetases associated domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158390_k127_4567939_6	749414.SBI_02059	2.607e-25	108.0	COG2706@1|root,COG2706@2|Bacteria,2GNMK@201174|Actinobacteria	201174|Actinobacteria	G	3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
SRR25158390_k127_4567939_1	749927.AMED_0286	9.09e-143	462.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4DZFV@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_4567939_4	446470.Snas_5102	2.525e-49	190.0	COG1247@1|root,COG1247@2|Bacteria,2I3KT@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_4567939_3	1206744.BAGL01000063_gene4772	9.123e-51	185.0	COG3797@1|root,COG3797@2|Bacteria,2HR3V@201174|Actinobacteria,4G0JG@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158390_k127_4567939_2	1120950.KB892763_gene5533	6.249e-124	402.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DQPN@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_4567939_0	1380356.JNIK01000013_gene4263	2.503e-189	602.0	COG1524@1|root,2Z9VM@2|Bacteria,2GWA2@201174|Actinobacteria,4EUKJ@85013|Frankiales	201174|Actinobacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4567939_5	110319.CF8_3838	2.894e-42	163.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4DVQW@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_465518_3	1120950.KB892767_gene5152	1.633e-89	296.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DP2I@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
SRR25158390_k127_465518_5	749414.SBI_00596	3.824e-72	244.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903136	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158390_k127_465518_6	1120950.KB892760_gene5743	2.475e-66	231.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DNDD@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903136	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158390_k127_465518_13	945712.CULC22_00471	3.315e-17	85.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,22NM6@1653|Corynebacteriaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	wblB	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158390_k127_465518_8	1121946.AUAX01000005_gene5427	4.124e-42	173.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4DC3B@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158390_k127_465518_10	37919.EP51_17675	4.275e-29	121.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4G32Q@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158390_k127_465518_14	1122602.ATXP01000002_gene793	5.657e-15	81.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,1W7EZ@1268|Micrococcaceae	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158390_k127_465518_7	356851.JOAN01000014_gene2138	2.276e-44	165.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4DFI0@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspX	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_465518_4	1385520.N802_09590	8.029e-73	262.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4FEA0@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR25158390_k127_465518_0	926564.KI911744_gene3754	2.719e-210	659.0	COG3693@1|root,COG3693@2|Bacteria,2I8RT@201174|Actinobacteria,4F3CJ@85017|Promicromonosporaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
SRR25158390_k127_465518_1	1713.JOFV01000002_gene530	1.304e-116	382.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4F0SN@85016|Cellulomonadaceae	201174|Actinobacteria	G	Inositol monophosphatase family	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158390_k127_465518_11	1385519.N801_14785	9.596e-25	107.0	COG1917@1|root,COG1917@2|Bacteria,2IQI4@201174|Actinobacteria,4FHHH@85021|Intrasporangiaceae	201174|Actinobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_465518_2	1206726.BAFV01000125_gene6525	2.934e-110	366.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4FY42@85025|Nocardiaceae	201174|Actinobacteria	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_465518_9	1120949.KB903303_gene6686	2.702e-38	146.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158390_k127_480329_0	1906.SFRA_01055	3.88e-299	924.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158390_k127_480329_1	1240349.ANGC01000035_gene3259	8.684e-31	123.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4G18A@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158390_k127_495794_39	1283287.KB822575_gene787	3.48e-39	156.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4DRDT@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_495794_9	1120950.KB892740_gene2533	7.186e-148	475.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4DPPP@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158390_k127_495794_6	471852.Tcur_3537	1.535e-190	607.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,4EH5V@85012|Streptosporangiales	201174|Actinobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158390_k127_495794_47	1394178.AWOO02000091_gene1040	1.857e-05	57.0	COG5662@1|root,COG5662@2|Bacteria,2I10N@201174|Actinobacteria,4EJDH@85012|Streptosporangiales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_495794_30	479433.Caci_9040	1.468e-64	229.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_495794_32	1120950.KB892740_gene2536	1.507e-60	227.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria,4DN49@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_495794_13	1298863.AUEP01000006_gene3472	1.775e-124	426.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4DNJI@85009|Propionibacteriales	201174|Actinobacteria	KLT	MviN-like protein	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158390_k127_495794_43	1246448.ANAZ01000003_gene5521	8.413e-27	128.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4EFQZ@85012|Streptosporangiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_495794_1	1306406.ASHX01000001_gene1744	3.55e-221	699.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158390_k127_495794_26	1157635.KB892009_gene3340	1.751e-76	260.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1,DUF742
SRR25158390_k127_495794_46	1229780.BN381_50071	4.833e-09	64.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR25158390_k127_495794_40	33876.JNXY01000026_gene3518	2.834e-38	147.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria,4DD3M@85008|Micromonosporales	201174|Actinobacteria	S	Roadblock lc7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR25158390_k127_495794_18	749414.SBI_03518	3.452e-94	347.0	COG4192@1|root,COG4251@1|root,COG4192@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158390_k127_495794_2	479435.Kfla_7020	4.38e-206	644.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4DNQF@85009|Propionibacteriales	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158390_k127_495794_27	1449353.JQMQ01000005_gene3044	4.323e-76	262.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,2NG3F@228398|Streptacidiphilus	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_495794_12	1193181.BN10_480013	9.458e-125	437.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4FEIA@85021|Intrasporangiaceae	201174|Actinobacteria	M	Penicillin-binding Protein	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158390_k127_495794_48	66874.JOFS01000018_gene3611	0.0001879	47.0	COG2026@1|root,COG2026@2|Bacteria,2ISBG@201174|Actinobacteria	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158390_k127_495794_15	1048339.KB913029_gene1636	2.579e-115	387.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4ES94@85013|Frankiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158390_k127_495794_14	1120950.KB892740_gene2546	3.987e-118	394.0	COG5542@1|root,COG5542@2|Bacteria,2HZNP@201174|Actinobacteria,4DTDM@85009|Propionibacteriales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158390_k127_495794_3	1123320.KB889562_gene6831	3.903e-205	649.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	yfbQ	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_495794_41	66869.JNXG01000030_gene855	7.475e-37	148.0	COG2045@1|root,COG2045@2|Bacteria,2GXP6@201174|Actinobacteria,41AKR@629295|Streptomyces griseus group	201174|Actinobacteria	H	2-phosphosulpholactate phosphatase	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158390_k127_495794_31	1120950.KB892745_gene2892	5.785e-63	222.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158390_k127_495794_45	47763.JNZA01000018_gene1532	6.961e-21	97.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_495794_37	1237500.ANBA01000016_gene4412	1.211e-42	161.0	COG3832@1|root,COG3832@2|Bacteria,2IHN6@201174|Actinobacteria,4EPBT@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_495794_7	469383.Cwoe_1072	7.826e-184	587.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4CRKJ@84995|Rubrobacteria	84995|Rubrobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18
SRR25158390_k127_495794_33	1120936.KB907212_gene5058	9.955e-54	201.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4EJA2@85012|Streptosporangiales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158390_k127_495794_35	1120950.KB892766_gene5076	5.913e-50	190.0	COG0666@1|root,COG0666@2|Bacteria,2I3AT@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158390_k127_495794_20	1120950.KB892794_gene2331	6.547e-87	297.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158390_k127_495794_0	1120950.KB892747_gene3715	0.0	1774.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,4DNZP@85009|Propionibacteriales	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	oplA	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158390_k127_495794_42	67281.JNZZ01000011_gene1141	1.306e-34	141.0	COG1011@1|root,COG1011@2|Bacteria,2IIV7@201174|Actinobacteria,41AN5@629295|Streptomyces griseus group	201174|Actinobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158390_k127_495794_38	1385521.N803_00700	2.223e-42	162.0	COG0494@1|root,COG0494@2|Bacteria,2IHSE@201174|Actinobacteria,4FHN1@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_495794_34	479435.Kfla_0145	1.053e-52	199.0	28MIG@1|root,2ZAV8@2|Bacteria,2IGFB@201174|Actinobacteria,4DQAF@85009|Propionibacteriales	201174|Actinobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
SRR25158390_k127_495794_24	1298863.AUEP01000009_gene90	6.122e-83	282.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4DQD7@85009|Propionibacteriales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158390_k127_495794_11	1120936.KB907218_gene3421	1.137e-130	422.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4EFGJ@85012|Streptosporangiales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158390_k127_495794_44	467200.ACFA01000480_gene1188	3.844e-24	110.0	2BYGI@1|root,333FU@2|Bacteria,2GRMH@201174|Actinobacteria	201174|Actinobacteria	S	Subtilisin inhibitor-like	-	-	-	-	-	-	-	-	-	-	-	-	SSI
SRR25158390_k127_495794_4	1869.MB27_37315	8.739e-200	628.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4DB9A@85008|Micromonosporales	201174|Actinobacteria	C	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158390_k127_495794_22	285535.JOEY01000020_gene2705	3.408e-85	291.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_495794_19	1048339.KB913029_gene1105	1.067e-91	318.0	COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,2GKXT@201174|Actinobacteria,4ERZU@85013|Frankiales	201174|Actinobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Globin,NAD_binding_1
SRR25158390_k127_495794_17	1157632.AQWQ01000003_gene1724	1.245e-104	347.0	COG3012@1|root,COG3012@2|Bacteria,2GJ7F@201174|Actinobacteria	201174|Actinobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158390_k127_495794_8	390989.JOEG01000004_gene4094	4.997e-183	595.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4D8RS@85008|Micromonosporales	201174|Actinobacteria	E	Arginine	arcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158390_k127_495794_25	1121017.AUFG01000002_gene2814	7.111e-77	265.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4FEG0@85021|Intrasporangiaceae	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_495794_10	196162.Noca_0168	3.113e-133	435.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4DN9M@85009|Propionibacteriales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158390_k127_495794_21	1122138.AQUZ01000036_gene5422	1.705e-85	295.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria,4DNGM@85009|Propionibacteriales	201174|Actinobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158390_k127_495794_16	1120950.KB892812_gene6976	6.656e-105	356.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4DN8Z@85009|Propionibacteriales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158390_k127_495794_5	743718.Isova_2848	9.703e-192	608.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4F4AK@85017|Promicromonosporaceae	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158390_k127_495794_29	585531.HMPREF0063_10493	3.546e-69	258.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4DQHS@85009|Propionibacteriales	201174|Actinobacteria	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158390_k127_495794_28	1120950.KB892747_gene3703	1.735e-73	254.0	COG1011@1|root,COG1011@2|Bacteria,2HZ7F@201174|Actinobacteria,4DQFA@85009|Propionibacteriales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase_like
SRR25158390_k127_495794_23	1121946.AUAX01000027_gene7969	3.568e-85	290.0	COG1234@1|root,COG1234@2|Bacteria,2GNG3@201174|Actinobacteria,4DD9F@85008|Micromonosporales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158390_k127_495794_36	1380354.JIAN01000005_gene2557	1.204e-42	167.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria,4F1B0@85016|Cellulomonadaceae	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158390_k127_500162_6	196162.Noca_3948	2.665e-30	134.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4DV3N@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158390_k127_500162_10	408672.NBCG_00446	2.145e-19	94.0	2EP6A@1|root,2ZIBI@2|Bacteria,2I04D@201174|Actinobacteria,4DVM5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_500162_8	446470.Snas_0565	6.446e-26	116.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRR25158390_k127_500162_2	1476876.JOJO01000019_gene429	2.836e-70	240.0	COG0346@1|root,COG0346@2|Bacteria,2IFCU@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_500162_1	479433.Caci_1818	5.163e-156	498.0	COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria	201174|Actinobacteria	K	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158390_k127_500162_5	1122622.ATWJ01000014_gene443	5.784e-45	174.0	COG2021@1|root,COG2021@2|Bacteria,2IMKC@201174|Actinobacteria,4FINJ@85021|Intrasporangiaceae	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_500162_13	67356.KL575598_gene5166	0.0001777	46.0	2CAP7@1|root,33DEX@2|Bacteria,2IMTH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SRR25158390_k127_500162_11	455632.SGR_5225	8.55e-13	72.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,419E4@629295|Streptomyces griseus group	201174|Actinobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158390_k127_500162_7	1120950.KB892754_gene5991	1.02e-29	126.0	COG1309@1|root,COG1309@2|Bacteria,2IKPS@201174|Actinobacteria,4DWUD@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_500162_0	1227484.C471_09695	1.074e-262	830.0	COG2217@1|root,arCOG01576@2157|Archaea,2XUPR@28890|Euryarchaeota,241DQ@183963|Halobacteria	183963|Halobacteria	P	heavy metal translocating P-type ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158390_k127_500162_12	1028805.GGC_0639	7.717e-08	57.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,1SJI0@1236|Gammaproteobacteria,1YAM7@135625|Pasteurellales	135625|Pasteurellales	C	Protein involved in metal ion binding and metal ion transport	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR25158390_k127_500162_3	1282361.ABAC402_07460	2.167e-63	237.0	COG0666@1|root,COG0666@2|Bacteria,1P877@1224|Proteobacteria,2U33E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0666 FOG Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2
SRR25158390_k127_500162_9	1499968.TCA2_5880	1.339e-19	96.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	merB	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB,Pyr_redox_dim
SRR25158390_k127_500162_4	450380.JPSY01000001_gene1864	2.501e-53	193.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158390_k127_504528_1	504472.Slin_0441	9.308e-43	163.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JHW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158390_k127_504528_0	616991.JPOO01000003_gene2107	8.102e-70	251.0	COG0436@1|root,COG0436@2|Bacteria,4PMV0@976|Bacteroidetes,1IK8A@117743|Flavobacteriia,23HY6@178469|Arenibacter	976|Bacteroidetes	E	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
SRR25158390_k127_512486_5	258052.JNYV01000004_gene4408	4.858e-43	168.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,Glyco_transf_4,UDPGT
SRR25158390_k127_512486_0	251221.35214398	1.311e-121	411.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158390_k127_512486_1	1108045.GORHZ_154_00380	7.043e-116	393.0	COG2197@1|root,COG2197@2|Bacteria,2I2R1@201174|Actinobacteria,4GDDU@85026|Gordoniaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_512486_2	1298863.AUEP01000005_gene2467	5.411e-91	303.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria,4DV4X@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158390_k127_512486_3	1298863.AUEP01000005_gene2466	8.607e-77	269.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,4DV2T@85009|Propionibacteriales	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158390_k127_512486_4	1348663.KCH_08100	2.932e-55	205.0	2ANI9@1|root,31DH5@2|Bacteria,2GJE8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_512486_6	543632.JOJL01000011_gene6777	3.157e-19	87.0	COG1082@1|root,COG3185@1|root,COG1082@2|Bacteria,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,4DHSS@85008|Micromonosporales	201174|Actinobacteria	EG	Xylose isomerase-like TIM barrel	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AP_endonuc_2,Glyoxalase,Glyoxalase_5
SRR25158390_k127_516101_6	159450.NH14_01305	9.83e-88	308.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
SRR25158390_k127_516101_15	1122611.KB904018_gene6901	1.518e-29	123.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4EGGU@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 31	yic1	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SRR25158390_k127_516101_1	469371.Tbis_2415	2.087e-175	564.0	COG2182@1|root,COG2182@2|Bacteria,2I2HB@201174|Actinobacteria,4EE5X@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_516101_2	408672.NBCG_00622	2.598e-166	542.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4DNTX@85009|Propionibacteriales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158390_k127_516101_17	1279015.KB908467_gene491	4.616e-19	101.0	29XMD@1|root,30JCN@2|Bacteria,1P97S@1224|Proteobacteria,1SVRE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_516101_19	710696.Intca_2217	1.123e-11	77.0	COG4932@1|root,COG4932@2|Bacteria,2IFAA@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_516101_10	512565.AMIS_43960	8.097e-63	226.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4DE30@85008|Micromonosporales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_516101_18	1123320.KB889710_gene8444	1.125e-18	86.0	COG3813@1|root,COG3813@2|Bacteria,2GRIY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
SRR25158390_k127_516101_9	1089545.KB913037_gene8931	5.192e-69	238.0	COG2346@1|root,COG2346@2|Bacteria,2IHUK@201174|Actinobacteria,4EBCZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158390_k127_516101_8	1172186.KB911468_gene1068	2.113e-69	246.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,2345A@1762|Mycobacteriaceae	201174|Actinobacteria	E	Lysine exporter protein LysE YggA	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158390_k127_516101_11	1122138.AQUZ01000011_gene4923	5.034e-59	221.0	COG3173@1|root,COG3173@2|Bacteria,2I35I@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.1.1.179	ko:K18844,ko:K18845	-	-	-	-	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	APH
SRR25158390_k127_516101_14	1121272.KB903250_gene2833	3.267e-33	133.0	2ED2V@1|root,336ZS@2|Bacteria,2IS2Q@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2568
SRR25158390_k127_516101_4	644283.Micau_2760	7.484e-147	473.0	COG3416@1|root,COG3416@2|Bacteria,2HVVA@201174|Actinobacteria,4DEHY@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158390_k127_516101_12	1121019.AUMN01000004_gene1480	1.721e-54	198.0	COG1309@1|root,COG1309@2|Bacteria,2IKQ8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_516101_20	58123.JOFJ01000018_gene4323	1.245e-07	62.0	2EFYZ@1|root,345PV@2|Bacteria,2I21S@201174|Actinobacteria,4EQB0@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_516101_13	1237500.ANBA01000004_gene2160	6.932e-41	161.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4EQ3W@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_516101_16	1122247.C731_2277	1.005e-23	107.0	COG0500@1|root,COG2226@2|Bacteria,2IGKC@201174|Actinobacteria,238UQ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_516101_3	656024.FsymDg_0954	4.208e-149	484.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4EUMZ@85013|Frankiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158390_k127_516101_5	1120950.KB892751_gene6781	6.082e-133	435.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4DQ7F@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_516101_0	1246995.AFR_25175	1.898e-226	721.0	COG0793@1|root,COG0793@2|Bacteria,2HFZM@201174|Actinobacteria	201174|Actinobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158390_k127_516101_7	1380370.JIBA01000015_gene304	4.233e-84	290.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4FI2F@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
SRR25158390_k127_517154_3	1240349.ANGC01000148_gene4814	9.804e-11	72.0	COG3666@1|root,COG3666@2|Bacteria,2IA0I@201174|Actinobacteria,4G2T6@85025|Nocardiaceae	201174|Actinobacteria	L	Protein involved in DNA binding, transposase activity and DNA transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR25158390_k127_517154_0	1122611.KB903986_gene4024	9.7e-45	166.0	2E11C@1|root,32WH8@2|Bacteria,2IKTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_517154_2	1120934.KB894429_gene1661	1.14e-19	98.0	COG0515@1|root,COG0515@2|Bacteria,2H1JG@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_517267_2	1120950.KB892741_gene2671	8.625e-169	534.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DNJX@85009|Propionibacteriales	201174|Actinobacteria	E	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_517267_5	1048339.KB913029_gene3460	2.209e-80	270.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4ESEU@85013|Frankiales	201174|Actinobacteria	E	Acetolactate synthase, small subunit	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158390_k127_517267_1	1120950.KB892741_gene2673	5.154e-182	573.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4DNFA@85009|Propionibacteriales	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158390_k127_517267_0	479435.Kfla_4884	7.659e-239	750.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DPA7@85009|Propionibacteriales	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158390_k127_517267_4	1120934.KB894405_gene5594	2.144e-87	296.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria,4E299@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
SRR25158390_k127_517267_6	479432.Sros_1908	9.317e-66	231.0	COG0586@1|root,COG0586@2|Bacteria,2HKKQ@201174|Actinobacteria,4EIYT@85012|Streptosporangiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158390_k127_517267_3	471853.Bcav_1417	9.563e-115	373.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158390_k127_53125_14	743718.Isova_0956	3.564e-21	94.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria,4F4GZ@85017|Promicromonosporaceae	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158390_k127_53125_12	479435.Kfla_1322	1.718e-54	203.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,4DS0K@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	yhjD	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158390_k127_53125_7	1120950.KB892760_gene5758	2.58e-70	252.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4DTSB@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR25158390_k127_53125_11	452652.KSE_46350	2.134e-62	218.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,2M2Q9@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	pecS	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158390_k127_53125_5	66429.JOFL01000004_gene3559	3.359e-88	298.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_53125_4	1463879.JOHP01000004_gene6427	3.876e-89	301.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_53125_3	479435.Kfla_5713	2.856e-155	496.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria,4DQ24@85009|Propionibacteriales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158390_k127_53125_8	1464048.JNZS01000016_gene3884	4.377e-68	237.0	COG0454@1|root,COG0454@2|Bacteria,2ID7A@201174|Actinobacteria,4DAFH@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158390_k127_53125_1	1136417.AZWE01000003_gene3458	5.135e-169	545.0	COG0531@1|root,COG0531@2|Bacteria,2GJ1D@201174|Actinobacteria,4DB22@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158390_k127_53125_13	391037.Sare_1730	2.365e-52	192.0	2E86Z@1|root,332K7@2|Bacteria,2ICI7@201174|Actinobacteria,4DC0H@85008|Micromonosporales	201174|Actinobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
SRR25158390_k127_53125_0	1385519.N801_12955	2.81e-191	609.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4FEQE@85021|Intrasporangiaceae	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158390_k127_53125_2	1123320.KB889688_gene425	5.694e-162	514.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158390_k127_53125_10	1032480.MLP_44890	1.137e-64	230.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4DQEY@85009|Propionibacteriales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158390_k127_53125_6	1048339.KB913029_gene515	3.073e-81	275.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4ESK5@85013|Frankiales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158390_k127_53125_9	1713.JOFV01000001_gene1905	1.476e-65	235.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4F28B@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR25158390_k127_537761_12	100226.SCO5506	5.902e-35	149.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_537761_14	1121019.AUMN01000038_gene23	3.01e-17	87.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158390_k127_537761_0	164757.Mjls_0414	6.152e-200	636.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,233VG@1762|Mycobacteriaceae	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_537761_4	1054860.KB913030_gene3436	8.323e-99	332.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158390_k127_537761_8	164757.Mjls_0415	1.578e-80	280.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_537761_7	1380356.JNIK01000006_gene1536	4.49e-90	301.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4ESIC@85013|Frankiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158390_k127_537761_9	1169161.KB897718_gene3267	3.019e-76	265.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158390_k127_537761_13	1380354.JIAN01000008_gene3290	7.478e-27	116.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_537761_16	479435.Kfla_0057	6.308e-14	81.0	2E4NY@1|root,31XN3@2|Bacteria,2GX73@201174|Actinobacteria,4DSQV@85009|Propionibacteriales	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
SRR25158390_k127_537761_11	397278.JOJN01000003_gene1724	6.931e-49	186.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4DRBX@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158390_k127_537761_6	479435.Kfla_0059	2.58e-95	317.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4DNQV@85009|Propionibacteriales	201174|Actinobacteria	EH	Peptidase C26	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158390_k127_537761_3	1907.SGLAU_17150	1.064e-147	490.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_537761_10	446470.Snas_6472	3.507e-67	249.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4EXQB@85014|Glycomycetales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_537761_2	1120950.KB892743_gene3151	1.314e-149	500.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4DP0A@85009|Propionibacteriales	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158390_k127_537761_1	585531.HMPREF0063_10447	1.951e-158	513.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DPN4@85009|Propionibacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158390_k127_537761_5	479435.Kfla_0063	2.23e-98	340.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4DNAN@85009|Propionibacteriales	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158390_k127_537761_15	2045.KR76_00270	6.282e-14	71.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4DQIX@85009|Propionibacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158390_k127_541055_3	479434.Sthe_1229	4.268e-107	359.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_541055_8	1035308.AQYY01000002_gene294	2.413e-34	137.0	2E4PM@1|root,32ZI9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_541055_6	713586.KB900536_gene1119	6.162e-49	183.0	COG0500@1|root,COG0500@2|Bacteria,1QYGH@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_541055_10	998674.ATTE01000001_gene3434	0.0007318	42.0	2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_541055_7	1343740.M271_25105	1.306e-40	164.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR25158390_k127_541055_0	1464048.JNZS01000009_gene5811	0.0	1278.0	COG0188@1|root,COG1372@1|root,COG0188@2|Bacteria,COG1372@2|Bacteria,2GJ2Q@201174|Actinobacteria	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV,Intein_splicing,LAGLIDADG_3
SRR25158390_k127_541055_1	351607.Acel_0005	6.905e-311	966.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4ES0Z@85013|Frankiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158390_k127_541055_4	935839.JAGJ01000008_gene1784	1.206e-78	282.0	COG1506@1|root,COG1506@2|Bacteria,2I2K7@201174|Actinobacteria,4F46X@85017|Promicromonosporaceae	201174|Actinobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C,Peptidase_S9
SRR25158390_k127_541055_5	1120950.KB892740_gene2516	2.261e-50	185.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4DR8Q@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158390_k127_541055_2	1449346.JQMO01000003_gene4382	1.359e-144	468.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,2M0JA@2063|Kitasatospora	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158390_k127_541055_9	405948.SACE_0004	8.342e-32	124.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4DYVC@85010|Pseudonocardiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158390_k127_541124_2	391623.TERMP_02179	1.907e-79	294.0	COG1361@1|root,COG1404@1|root,arCOG03610@1|root,arCOG00704@2157|Archaea,arCOG02079@2157|Archaea,arCOG03610@2157|Archaea,2XV8N@28890|Euryarchaeota,243CT@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S8 family	pls	GO:0005575,GO:0005623,GO:0031975,GO:0044464	-	-	-	-	-	-	-	-	-	-	CARDB,PPC,Peptidase_S8
SRR25158390_k127_541124_1	1380393.JHVP01000001_gene2176	3.557e-87	301.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4EUBH@85013|Frankiales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_541124_4	644283.Micau_4583	3.143e-09	67.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4DCYF@85008|Micromonosporales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158390_k127_541124_0	35754.JNYJ01000004_gene5860	1.145e-123	411.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4D9XT@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_541124_3	66897.DJ64_27910	9.052e-43	157.0	COG0300@1|root,COG0300@2|Bacteria,2GK2K@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_542363_2	1120949.KB903339_gene7989	2.472e-63	229.0	COG0346@1|root,COG0454@1|root,COG0346@2|Bacteria,COG0456@2|Bacteria,2GMTB@201174|Actinobacteria,4DBF4@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_542363_0	1027371.GOALK_070_00010	3.093e-133	437.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,4GFSJ@85026|Gordoniaceae	201174|Actinobacteria	L	PFAM integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_542363_1	526226.Gbro_2670	3.505e-119	392.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,4GFWP@85026|Gordoniaceae	201174|Actinobacteria	L	integrase domain protein SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_542363_3	1283283.ATXA01000005_gene2208	9.405e-55	197.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4EWWQ@85013|Frankiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_552753_1	644283.Micau_0823	1.784e-113	371.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D8ZV@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_552753_0	479431.Namu_0806	2.147e-240	758.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERP6@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_554786_11	1380356.JNIK01000003_gene1189	1.468e-31	137.0	2AR9G@1|root,31GJC@2|Bacteria,2GN9V@201174|Actinobacteria,4EWX7@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
SRR25158390_k127_554786_0	1120950.KB892769_gene5396	2.753e-145	474.0	COG1228@1|root,COG1228@2|Bacteria,2GKRZ@201174|Actinobacteria,4DP0W@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_554786_7	1121927.GOHSU_64_00050	6.264e-51	189.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4GDSV@85026|Gordoniaceae	201174|Actinobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158390_k127_554786_10	1122609.AUGT01000022_gene641	4.23e-32	126.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4DRVC@85009|Propionibacteriales	201174|Actinobacteria	S	KH domain	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158390_k127_554786_3	68260.JOAY01000021_gene1699	2.604e-66	230.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158390_k127_554786_1	58123.JOFJ01000003_gene2043	4.109e-111	366.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4EGB1@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158390_k127_554786_6	351607.Acel_1557	1.001e-57	205.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4ESVQ@85013|Frankiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158390_k127_554786_5	266940.Krad_1404	4.713e-61	218.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158390_k127_554786_8	479433.Caci_1520	7.954e-49	179.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158390_k127_554786_2	1298863.AUEP01000002_gene1392	2.962e-93	314.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4DPWD@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158390_k127_554786_9	365528.KB891241_gene6155	5.734e-35	138.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4ETCV@85013|Frankiales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158390_k127_554786_4	58123.JOFJ01000003_gene2036	3.299e-66	237.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4EGPK@85012|Streptosporangiales	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158390_k127_55501_5	543632.JOJL01000042_gene4549	3.776e-12	72.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158390_k127_55501_1	1120950.KB892707_gene4780	1.152e-80	299.0	COG0454@1|root,COG0454@2|Bacteria,2H2PG@201174|Actinobacteria,4DNDQ@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158390_k127_55501_0	1120950.KB892707_gene4781	6.223e-132	431.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4DMYU@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158390_k127_55501_2	1032480.MLP_42050	2.708e-57	202.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4DR9B@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158390_k127_55501_4	196162.Noca_3143	3.536e-23	100.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria,4DSIR@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158390_k127_55501_3	1120936.KB907210_gene5871	2.258e-38	145.0	COG1104@1|root,COG1104@2|Bacteria,2GJ2B@201174|Actinobacteria,4EHSY@85012|Streptosporangiales	201174|Actinobacteria	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,TusA
SRR25158390_k127_555476_0	287986.DV20_26385	8.303e-283	891.0	COG5297@1|root,COG5297@2|Bacteria,2GMQN@201174|Actinobacteria,4E1F4@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_4_9,CelD_N,Glyco_hydro_9,fn3
SRR25158390_k127_555476_1	479432.Sros_0944	1.007e-109	365.0	COG1609@1|root,COG1609@2|Bacteria,2I8HR@201174|Actinobacteria,4EHUY@85012|Streptosporangiales	201174|Actinobacteria	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3
SRR25158390_k127_555476_2	1122611.KB903957_gene106	1.24e-53	202.0	COG0515@1|root,COG0515@2|Bacteria,2GMUX@201174|Actinobacteria,4EHQK@85012|Streptosporangiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158390_k127_555709_23	1394178.AWOO02000027_gene5256	2.795e-21	94.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4EHJ3@85012|Streptosporangiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_555709_25	1385518.N798_11035	1.413e-13	81.0	2E9GJ@1|root,333PP@2|Bacteria	2|Bacteria	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
SRR25158390_k127_555709_22	1120950.KB892749_gene3314	8.666e-27	116.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria,4DRX7@85009|Propionibacteriales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_555709_24	1120950.KB892749_gene3315	1.328e-20	93.0	COG4770@1|root,COG4770@2|Bacteria,2I2DF@201174|Actinobacteria,4DSRA@85009|Propionibacteriales	201174|Actinobacteria	I	Biotin-requiring enzyme	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158390_k127_555709_26	1122138.AQUZ01000025_gene2793	7.164e-10	70.0	2DRIE@1|root,33BXS@2|Bacteria,2GYYF@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158390_k127_555709_21	1120950.KB892749_gene3318	9.437e-31	125.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4DS64@85009|Propionibacteriales	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158390_k127_555709_12	1996.JOFO01000002_gene5728	1.371e-101	335.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4EHPQ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_555709_17	1206101.AZXC01000016_gene3564	3.622e-61	218.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158390_k127_555709_14	408672.NBCG_04295	3.378e-97	323.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4DPFJ@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158390_k127_555709_19	263358.VAB18032_04235	2.68e-46	173.0	COG2259@1|root,COG2259@2|Bacteria,2HD6Y@201174|Actinobacteria,4DD5K@85008|Micromonosporales	201174|Actinobacteria	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158390_k127_555709_3	110319.CF8_1378	1.124e-178	570.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DNC2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158390_k127_555709_10	1120950.KB892749_gene3327	2.521e-135	441.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4DNJ3@85009|Propionibacteriales	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158390_k127_555709_5	1128421.JAGA01000002_gene1493	6.725e-147	479.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	pel	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase_C
SRR25158390_k127_555709_9	269800.Tfu_1702	3.447e-140	461.0	COG1653@1|root,COG1653@2|Bacteria,2GK12@201174|Actinobacteria,4EHQZ@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_555709_8	1246448.ANAZ01000008_gene2331	8.596e-141	452.0	COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria,4EG4J@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_555709_6	269800.Tfu_1704	4.321e-146	469.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4EG0B@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_555709_7	644283.Micau_3546	3.33e-141	458.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4D8YA@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158390_k127_555709_2	263358.VAB18032_24020	1.933e-201	636.0	COG0673@1|root,COG0673@2|Bacteria,2GJNE@201174|Actinobacteria,4D9US@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_555709_0	644283.Micau_3548	7.294e-245	765.0	COG1904@1|root,COG1904@2|Bacteria,2I8PE@201174|Actinobacteria,4D998@85008|Micromonosporales	201174|Actinobacteria	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
SRR25158390_k127_555709_1	1121272.KB903251_gene655	5.72e-232	723.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4DARD@85008|Micromonosporales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158390_k127_555709_4	219305.MCAG_00412	4.529e-176	569.0	COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4DBDG@85008|Micromonosporales	201174|Actinobacteria	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
SRR25158390_k127_555709_11	1150864.MILUP08_43918	2.074e-116	400.0	COG0673@1|root,COG0673@2|Bacteria,2GKJX@201174|Actinobacteria,4DBQS@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158390_k127_555709_15	1150864.MILUP08_43908	1.622e-93	314.0	COG0673@1|root,COG0673@2|Bacteria,2H6HX@201174|Actinobacteria,4D8GF@85008|Micromonosporales	201174|Actinobacteria	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
SRR25158390_k127_555709_18	1463854.JOHT01000003_gene6049	2.565e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,2IFBN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_555709_16	1120949.KB903294_gene4302	1.764e-63	220.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N,Polyketide_cyc2,adh_short
SRR25158390_k127_555709_13	408672.NBCG_00625	1.915e-101	340.0	COG0491@1|root,COG0491@2|Bacteria,2GN7R@201174|Actinobacteria	201174|Actinobacteria	S	PFAM beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158390_k127_555709_20	1121380.JNIW01000020_gene3587	3.516e-37	145.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158390_k127_571603_1	479432.Sros_5509	2.178e-89	302.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4EJ84@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158390_k127_571603_2	479432.Sros_8728	4.155e-59	213.0	COG2128@1|root,COG2128@2|Bacteria,2HSVU@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158390_k127_571603_0	479432.Sros_8727	4.074e-168	539.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4EMDK@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_571603_3	1123501.KB902278_gene717	1.168e-56	207.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,2TSIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase,TAT_signal
SRR25158390_k127_624721_14	1108045.GORHZ_227_00260	4.2e-32	132.0	2DM0Y@1|root,318KY@2|Bacteria,2IMIX@201174|Actinobacteria,4GE4V@85026|Gordoniaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
SRR25158390_k127_624721_8	269800.Tfu_0764	1.546e-78	273.0	COG2520@1|root,COG2520@2|Bacteria,2IFXZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158390_k127_624721_7	1192034.CAP_4028	9.441e-80	275.0	COG4912@1|root,COG4912@2|Bacteria,1QSBJ@1224|Proteobacteria,42QNI@68525|delta/epsilon subdivisions,2WN26@28221|Deltaproteobacteria,2YW3J@29|Myxococcales	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158390_k127_624721_16	1122138.AQUZ01000001_gene1616	5.994e-12	69.0	2F90D@1|root,341C4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_624721_17	1403313.AXBR01000014_gene2201	0.0005401	43.0	2BTFW@1|root,32NN5@2|Bacteria,1UB53@1239|Firmicutes,4IMHN@91061|Bacilli,1ZK6C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_624721_12	1306174.JODP01000003_gene1881	1.721e-56	201.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158390_k127_624721_0	1123321.KB905813_gene810	6.645e-217	682.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria	201174|Actinobacteria	F	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158390_k127_624721_11	1003195.SCAT_0959	2.255e-58	212.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158390_k127_624721_10	1122622.ATWJ01000010_gene1179	4.703e-76	262.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4FGBN@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158390_k127_624721_6	1123320.KB889701_gene9186	3.724e-95	324.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158390_k127_624721_13	1123024.AUII01000041_gene1731	1.72e-44	169.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4E4D4@85010|Pseudonocardiales	201174|Actinobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158390_k127_624721_5	1120950.KB892767_gene5145	2.919e-98	329.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DNT7@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158390_k127_624721_9	58123.JOFJ01000001_gene2902	2.157e-76	263.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4EG7D@85012|Streptosporangiales	201174|Actinobacteria	K	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158390_k127_624721_4	1122609.AUGT01000002_gene4078	1.123e-108	366.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4DMYR@85009|Propionibacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158390_k127_624721_3	1048339.KB913029_gene4082	5.016e-121	395.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158390_k127_624721_2	1120950.KB892767_gene5149	2.58e-130	423.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DNSC@85009|Propionibacteriales	201174|Actinobacteria	L	tyrosine recombinase	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158390_k127_624721_1	479435.Kfla_5119	5.123e-181	573.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4DNSB@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158390_k127_624721_15	42256.RradSPS_1687	6.234e-20	90.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158390_k127_62661_1	1038860.AXAP01000089_gene3716	2.678e-50	190.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,3K2UM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_62661_0	331869.BAL199_20455	1.373e-73	259.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4BPE5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	MA20_08005	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158390_k127_630081_13	1227499.C493_06592	3.189e-72	248.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT8F@28890|Euryarchaeota,23SGR@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_630081_16	313589.JNB_10709	5.125e-54	196.0	COG1309@1|root,COG1309@2|Bacteria,2IIY2@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_630081_9	68170.KL590563_gene3121	1.149e-114	374.0	COG2518@1|root,COG2518@2|Bacteria,2I37N@201174|Actinobacteria,4E6FJ@85010|Pseudonocardiales	201174|Actinobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158390_k127_630081_14	1048339.KB913029_gene3275	1.141e-69	248.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4ESUY@85013|Frankiales	201174|Actinobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158390_k127_630081_17	391735.Veis_4531	5.064e-36	141.0	COG2329@1|root,COG2329@2|Bacteria,1QTY7@1224|Proteobacteria,2WHMJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158390_k127_630081_12	1404245.CGLY_05625	8.424e-91	310.0	COG4335@1|root,COG4335@2|Bacteria,2HDE9@201174|Actinobacteria,22MW4@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158390_k127_630081_20	251221.35213055	0.0009685	48.0	COG0629@1|root,COG0629@2|Bacteria,1G6JH@1117|Cyanobacteria	1117|Cyanobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158390_k127_630081_11	471852.Tcur_2164	2.656e-103	349.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4EH8G@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158390_k127_630081_10	1123320.KB889589_gene4237	3.77e-111	366.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria	201174|Actinobacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158390_k127_630081_5	1123320.KB889589_gene4238	6.852e-129	421.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158390_k127_630081_2	1123320.KB889589_gene4239	1.603e-212	677.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158390_k127_630081_3	1120950.KB892767_gene5181	2.731e-165	528.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4DNDI@85009|Propionibacteriales	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158390_k127_630081_18	1394178.AWOO02000020_gene7387	3.495e-35	149.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4EIXP@85012|Streptosporangiales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158390_k127_630081_15	28444.JODQ01000004_gene6102	4.332e-68	241.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4EG6C@85012|Streptosporangiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_630081_6	1123320.KB889701_gene9163	3.46e-125	419.0	COG0728@1|root,COG0728@2|Bacteria,2GKWW@201174|Actinobacteria	201174|Actinobacteria	M	virulence factor MVIN family protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158390_k127_630081_0	446469.Sked_05510	3.003e-246	769.0	COG3534@1|root,COG3534@2|Bacteria,2GMAK@201174|Actinobacteria	201174|Actinobacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SRR25158390_k127_630081_4	1122611.KB904018_gene6868	1.541e-135	439.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4EFM9@85012|Streptosporangiales	201174|Actinobacteria	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_630081_1	1463825.JNXC01000009_gene1427	1.196e-231	726.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4DYXK@85010|Pseudonocardiales	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
SRR25158390_k127_630081_7	35754.JNYJ01000001_gene7194	9.967e-119	394.0	COG1172@1|root,COG1172@2|Bacteria,2GM6S@201174|Actinobacteria,4DAXF@85008|Micromonosporales	201174|Actinobacteria	G	Ribose xylose arabinose galactoside ABC-type transport systems, permease components	rhaP	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
SRR25158390_k127_630081_8	1068978.AMETH_2135	7.194e-117	387.0	COG1172@1|root,COG1172@2|Bacteria,2GM2F@201174|Actinobacteria,4DX6R@85010|Pseudonocardiales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	rhaQ	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
SRR25158390_k127_630470_1	1254432.SCE1572_16670	4.009e-12	75.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	CBM_2,GSDH
SRR25158390_k127_630470_0	251221.35213651	4.875e-70	248.0	COG3217@1|root,COG3217@2|Bacteria,1G41J@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158390_k127_630689_10	1385521.N803_10965	2.867e-14	76.0	COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_630689_9	1385521.N803_10960	2.25e-28	119.0	COG1848@1|root,COG1848@2|Bacteria,2IR37@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_630689_6	471852.Tcur_3132	1.606e-87	295.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4EII3@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158390_k127_630689_2	446471.Xcel_2470	1.175e-125	417.0	COG3397@1|root,COG3397@2|Bacteria,2GP7X@201174|Actinobacteria	201174|Actinobacteria	G	Chitin-binding domain 3 protein	-	-	-	ko:K03933	-	-	-	-	ko00000	-	AA10,CBM73	-	CBM_2,LPMO_10
SRR25158390_k127_630689_8	1079986.JH164846_gene2038	1.707e-82	287.0	COG1609@1|root,COG1609@2|Bacteria,2ICJM@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_630689_3	33898.JRHJ01000023_gene6764	1.969e-125	421.0	COG1653@1|root,COG1653@2|Bacteria,2I8TG@201174|Actinobacteria	201174|Actinobacteria	G	transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
SRR25158390_k127_630689_5	316274.Haur_1151	3.278e-88	306.0	COG1175@1|root,COG1175@2|Bacteria,2G8BY@200795|Chloroflexi,3773P@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_630689_7	1173020.Cha6605_0368	7.085e-86	293.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_630689_4	263358.VAB18032_19415	6.499e-94	320.0	COG1621@1|root,COG1621@2|Bacteria,2H3S0@201174|Actinobacteria,4D9A3@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolases family 32 N-terminal domain	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
SRR25158390_k127_630689_1	1306174.JODP01000006_gene3392	2.382e-136	441.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	malR	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_630689_0	471852.Tcur_1739	3.369e-276	857.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4EI1B@85012|Streptosporangiales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158390_k127_632213_0	1120950.KB892801_gene1726	3.018e-134	432.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DSY9@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the complex I 49 kDa subunit family	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158390_k127_632213_2	1120950.KB892801_gene1727	2.218e-56	205.0	COG3402@1|root,COG3402@2|Bacteria,2IR88@201174|Actinobacteria,4DRVV@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158390_k127_632213_1	1120950.KB892801_gene1729	2.607e-132	439.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4DQ4J@85009|Propionibacteriales	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158390_k127_643945_0	471853.Bcav_2088	1.647e-95	317.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_643945_1	1068980.ARVW01000001_gene6451	6.49e-73	251.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria,4EAHZ@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_643945_4	1121933.AUHH01000008_gene1069	0.0009163	43.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria,4DQ91@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_643945_2	1075090.GOAMR_12_00510	1.108e-58	205.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria,4GF84@85026|Gordoniaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_643945_3	1075090.GOAMR_12_00500	9.924e-56	201.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4GB6P@85026|Gordoniaceae	201174|Actinobacteria	K	RNA polymerase sigma factor containing a TPR repeat domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_658648_0	390989.JOEG01000012_gene3459	3.613e-222	700.0	COG0451@1|root,COG0560@1|root,COG0451@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4,Sterile
SRR25158390_k127_658648_2	1298880.AUEV01000004_gene1862	8.016e-163	541.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158390_k127_658648_6	1298880.AUEV01000004_gene1861	4.562e-49	178.0	COG2018@1|root,COG2018@2|Bacteria,2IFF6@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SRR25158390_k127_658648_7	1056816.JAFQ01000004_gene3617	4.483e-08	60.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria,4G2JS@85025|Nocardiaceae	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR25158390_k127_658648_4	68219.JNXI01000003_gene4748	1.745e-83	281.0	COG2229@1|root,COG2229@2|Bacteria,2GM4V@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_1
SRR25158390_k127_658648_1	500153.JOEK01000004_gene776	4.104e-183	582.0	COG0644@1|root,COG0644@2|Bacteria,2GMH9@201174|Actinobacteria	201174|Actinobacteria	C	geranylgeranyl reductase	fixC	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like
SRR25158390_k127_658648_5	1121377.KB906401_gene3385	5.177e-54	201.0	29YCS@1|root,30K75@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_658648_3	1463854.JOHT01000008_gene5793	5.445e-92	306.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158390_k127_6593_1	1283299.AUKG01000002_gene5200	9.549e-29	117.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CR5F@84995|Rubrobacteria	84995|Rubrobacteria	F	Dihydroorotate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DHO_dh
SRR25158390_k127_6593_0	1120950.KB892708_gene4316	0.0	1421.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4DNSQ@85009|Propionibacteriales	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158390_k127_670103_2	251221.35212406	5.237e-09	67.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria	1117|Cyanobacteria	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
SRR25158390_k127_670103_1	1121456.ATVA01000013_gene1180	5.326e-11	75.0	COG2207@1|root,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,43ARB@68525|delta/epsilon subdivisions,2X69Z@28221|Deltaproteobacteria,2MH0G@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158390_k127_670103_0	1123065.ATWL01000006_gene2320	8.612e-16	91.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158390_k127_672369_11	477228.YO5_10754	8.685e-34	137.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1S3FE@1236|Gammaproteobacteria,1YZU9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158390_k127_672369_10	358823.DF19_12165	4.315e-44	171.0	COG1309@1|root,COG1309@2|Bacteria,2HR0A@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	yxaF_2	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
SRR25158390_k127_672369_6	1122182.KB903839_gene1035	1.29e-109	365.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4D8QG@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158390_k127_672369_8	44060.JODL01000003_gene2720	1.527e-94	319.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_672369_9	397278.JOJN01000001_gene2592	1.704e-52	198.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DPC3@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158390_k127_672369_7	1288083.AUKR01000001_gene1210	6.322e-97	324.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158390_k127_672369_3	469371.Tbis_1328	6.053e-150	481.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria,4E2JX@85010|Pseudonocardiales	201174|Actinobacteria	E	DAHP synthetase I family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158390_k127_672369_5	1120950.KB892707_gene4856	9.052e-133	432.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4DPQR@85009|Propionibacteriales	201174|Actinobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158390_k127_672369_1	469371.Tbis_1899	9.409e-217	685.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4DZSR@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158390_k127_672369_2	367299.JOEE01000001_gene1827	1.478e-190	608.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.90	ko:K00895	ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130	-	R00764,R02073	RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158390_k127_672369_0	526225.Gobs_5018	2.495e-288	895.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4ERY2@85013|Frankiales	201174|Actinobacteria	E	asparagine	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158390_k127_672369_4	526225.Gobs_5017	4.3e-133	436.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,2GN0U@201174|Actinobacteria,4ET1C@85013|Frankiales	201174|Actinobacteria	HJK	D-ala D-ala ligase C-terminus	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158390_k127_681901_4	2074.JNYD01000008_gene1049	4.496e-36	154.0	COG2144@1|root,COG2144@2|Bacteria,2GM78@201174|Actinobacteria,4E1YB@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR synthase related protein, C-terminal domain	thiL_1	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10
SRR25158390_k127_681901_1	675635.Psed_6288	5.453e-90	304.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4E51E@85010|Pseudonocardiales	201174|Actinobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158390_k127_681901_2	196162.Noca_4817	6.759e-75	262.0	2DBFP@1|root,2Z8ZG@2|Bacteria,2IAVA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_681901_0	1123024.AUII01000034_gene2683	1.271e-181	582.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4E8M1@85010|Pseudonocardiales	201174|Actinobacteria	F	Lyase	-	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158390_k127_681901_3	1123024.AUII01000034_gene2682	2.264e-60	223.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4EBSU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158390_k127_684556_9	1298863.AUEP01000014_gene1616	1.403e-112	372.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4DNI1@85009|Propionibacteriales	201174|Actinobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
SRR25158390_k127_684556_0	1157637.KB892090_gene6571	0.0	2335.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria	201174|Actinobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158390_k127_684556_11	1033730.CAHG01000016_gene490	2.175e-86	291.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4DPSU@85009|Propionibacteriales	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158390_k127_684556_8	67257.JODR01000007_gene3803	5.129e-116	383.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158390_k127_684556_10	1048339.KB913029_gene4533	7.478e-94	331.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4ERZA@85013|Frankiales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158390_k127_684556_2	1306174.JODP01000013_gene7463	1.962e-194	617.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
SRR25158390_k127_684556_7	1120950.KB892707_gene4966	6.683e-121	398.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158390_k127_684556_14	68170.KL590474_gene5824	1.575e-16	83.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DZNW@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_684556_15	1463887.KL589971_gene4496	9.442e-09	61.0	290XR@1|root,2ZNJH@2|Bacteria,2IQ97@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_684556_13	526225.Gobs_3219	1.367e-18	97.0	2EGC7@1|root,33A40@2|Bacteria,2HEC9@201174|Actinobacteria,4ETGQ@85013|Frankiales	201174|Actinobacteria	S	Trp biosynthesis associated, transmembrane protein, Oprn Chp	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
SRR25158390_k127_684556_1	1120950.KB892707_gene4953	2.339e-219	691.0	COG1169@1|root,COG1169@2|Bacteria,2I50A@201174|Actinobacteria,4DX2J@85009|Propionibacteriales	201174|Actinobacteria	HQ	Anthranilate synthase component I, N terminal region	trpE	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158390_k127_684556_12	67281.JNZZ01000031_gene3641	1.607e-50	182.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,41AY8@629295|Streptomyces griseus group	201174|Actinobacteria	E	Phosphoribosyl-AMP cyclohydrolase	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
SRR25158390_k127_684556_5	1306990.BARG01000024_gene2594	7.295e-150	511.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158390_k127_684556_6	479432.Sros_7205	3.734e-141	457.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4EMEV@85012|Streptosporangiales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_684556_3	479432.Sros_7204	1.705e-182	583.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4EMXZ@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_684556_4	1246448.ANAZ01000026_gene3386	5.399e-169	550.0	COG0747@1|root,COG0747@2|Bacteria,2GMMG@201174|Actinobacteria	201174|Actinobacteria	E	extracellular solute-binding protein, family 5	-	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044444,GO:0044464	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_70336_7	1298880.AUEV01000021_gene838	2.109e-21	96.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding domain, excisionase family	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158390_k127_70336_3	1120950.KB892801_gene1769	1.128e-129	422.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DPEE@85009|Propionibacteriales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
SRR25158390_k127_70336_1	1120950.KB892801_gene1770	4.223e-135	437.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,4DNTT@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158390_k127_70336_6	1137269.AZWL01000027_gene1722	3.215e-28	118.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Glutaredoxin 2	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158390_k127_70336_0	28444.JODQ01000003_gene4703	8.904e-136	445.0	COG3525@1|root,COG3525@2|Bacteria,2H28J@201174|Actinobacteria,4EHGX@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
SRR25158390_k127_70336_5	1214101.BN159_3980	2.188e-96	323.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158390_k127_70336_2	1380346.JNIH01000002_gene6267	9.014e-135	443.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158390_k127_70336_4	110319.CF8_0423	7.795e-103	361.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4DN1M@85009|Propionibacteriales	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
SRR25158390_k127_70336_8	1193181.BN10_240004	3.511e-09	67.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4FF2G@85021|Intrasporangiaceae	201174|Actinobacteria	H	Uroporphyrin-III C-methyltransferase	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158390_k127_708888_1	1380370.JIBA01000013_gene1539	1.151e-66	228.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4FFXT@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158390_k127_708888_0	446462.Amir_5190	3.818e-101	343.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4E0XZ@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158390_k127_708888_2	471852.Tcur_2202	3.262e-40	150.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria,4EJFH@85012|Streptosporangiales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158390_k127_710557_2	471853.Bcav_4079	2.229e-52	196.0	COG1277@1|root,COG1277@2|Bacteria,2IG8D@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158390_k127_710557_0	471853.Bcav_4078	1.347e-130	423.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_710557_1	1121272.KB903290_gene4574	1.974e-52	194.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4D9VC@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158390_k127_721302_9	1120950.KB892748_gene3264	3.584e-45	171.0	2AQ7N@1|root,31FDD@2|Bacteria,2IFXR@201174|Actinobacteria,4DRWQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_721302_1	590998.Celf_2588	5.643e-166	527.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4F29M@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158390_k127_721302_10	365528.KB891102_gene4490	3.281e-29	131.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4ET37@85013|Frankiales	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	ribD	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158390_k127_721302_0	1179773.BN6_15580	7.196e-216	692.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DYSY@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
SRR25158390_k127_721302_5	1385521.N803_07445	1.096e-107	356.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4FFBT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158390_k127_721302_8	35754.JNYJ01000043_gene4535	2.328e-53	198.0	COG1975@1|root,COG1975@2|Bacteria,2IK3Z@201174|Actinobacteria,4DEB9@85008|Micromonosporales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C
SRR25158390_k127_721302_2	1463857.JOFZ01000010_gene4347	1.198e-155	502.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158390_k127_721302_7	867903.ThesuDRAFT_01144	2.117e-56	207.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,247XS@186801|Clostridia	186801|Clostridia	IQ	Dehydrogenase	ydaD	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_721302_6	1380390.JIAT01000012_gene3169	3.715e-80	282.0	COG1064@1|root,COG1064@2|Bacteria	1380390.JIAT01000012_gene3169|-	P	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_721302_4	1380390.JIAT01000012_gene3168	8.648e-119	393.0	COG1960@1|root,COG1960@2|Bacteria,2IBGY@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_721302_3	1095767.CAHD01000199_gene2406	6.81e-135	437.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4F0HX@85016|Cellulomonadaceae	201174|Actinobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SRR25158390_k127_722781_0	1384056.N787_09565	6.841e-193	608.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,1RMSV@1236|Gammaproteobacteria,1X31I@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158390_k127_722781_1	1120978.KB894080_gene1273	1.382e-26	111.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,27GNW@186828|Carnobacteriaceae	91061|Bacilli	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
SRR25158390_k127_740862_0	1123251.ATWM01000007_gene2371	4.224e-143	469.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,4FF86@85021|Intrasporangiaceae	201174|Actinobacteria	S	proteinase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158390_k127_740862_1	479435.Kfla_0591	1.561e-136	439.0	COG1774@1|root,COG1774@2|Bacteria,2HYDT@201174|Actinobacteria,4DT53@85009|Propionibacteriales	201174|Actinobacteria	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR25158390_k127_740862_3	479431.Namu_5134	1.805e-82	286.0	COG3153@1|root,COG3153@2|Bacteria,2I3ZT@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_740862_2	1122138.AQUZ01000105_gene2472	1.482e-120	399.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4DNVR@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158390_k127_740862_4	469371.Tbis_3467	2.231e-70	244.0	COG0125@1|root,COG0477@1|root,COG0125@2|Bacteria,COG0477@2|Bacteria,2GNTI@201174|Actinobacteria,4DYRV@85010|Pseudonocardiales	201174|Actinobacteria	EFGP	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR25158390_k127_740862_5	35754.JNYJ01000043_gene4438	1.094e-38	157.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4DIVE@85008|Micromonosporales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158390_k127_750233_0	1120950.KB892747_gene3674	6.693e-135	432.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4DNME@85009|Propionibacteriales	201174|Actinobacteria	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158390_k127_750233_1	1120950.KB892747_gene3676	1.311e-60	214.0	COG0454@1|root,COG0456@2|Bacteria,2I2XB@201174|Actinobacteria,4DQWV@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_750233_2	1268303.RHODMAR_3767	2.891e-49	180.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,4FVR0@85025|Nocardiaceae	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158390_k127_751252_3	1122138.AQUZ01000006_gene1452	2.283e-43	161.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4DR6U@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_751252_0	479435.Kfla_5413	6.294e-298	921.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4DP71@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
SRR25158390_k127_751252_2	196162.Noca_3523	1.818e-77	269.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria,4DQCG@85009|Propionibacteriales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158390_k127_751252_1	215803.DB30_8111	3.582e-103	350.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,437XM@68525|delta/epsilon subdivisions,2X9RD@28221|Deltaproteobacteria,2YUQ7@29|Myxococcales	28221|Deltaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR25158390_k127_751252_4	215803.DB30_8113	4.321e-10	62.0	COG4213@1|root,COG4213@2|Bacteria,1R4J2@1224|Proteobacteria,43B1Y@68525|delta/epsilon subdivisions,2X6G1@28221|Deltaproteobacteria,2Z3AX@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158390_k127_767625_2	928724.SacglDRAFT_03074	3.342e-15	76.0	COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,2IAU4@201174|Actinobacteria,4E21M@85010|Pseudonocardiales	201174|Actinobacteria	MQ	PFAM Methyltransferase domain	-	-	2.1.1.156,2.1.1.157	ko:K18896,ko:K18897	ko00260,map00260	-	R10060,R10061	RC00003,RC03038,RC03040	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_767625_1	981369.JQMJ01000004_gene6483	2.008e-62	224.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,2NEQE@228398|Streptacidiphilus	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158390_k127_767625_0	2002.JOEQ01000002_gene4343	7.961e-70	246.0	COG5479@1|root,COG5479@2|Bacteria,2GMJR@201174|Actinobacteria,4EJ9Y@85012|Streptosporangiales	201174|Actinobacteria	M	Protein of unknown function (DUF3152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3152
SRR25158390_k127_773496_9	1120950.KB892746_gene3485	4.459e-51	186.0	COG3154@1|root,COG3154@2|Bacteria,2INVN@201174|Actinobacteria,4DSBS@85009|Propionibacteriales	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158390_k127_773496_11	644283.Micau_2045	2.171e-32	134.0	COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria,4DINI@85008|Micromonosporales	201174|Actinobacteria	Q	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
SRR25158390_k127_773496_4	1120950.KB892823_gene530	1.02e-143	458.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DNTD@85009|Propionibacteriales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRR25158390_k127_773496_0	1380347.JNII01000006_gene1603	5.776e-321	989.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158390_k127_773496_7	1122247.C731_0438	2.241e-119	391.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria,233C0@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_773496_6	1095767.CAHD01000009_gene2154	5.67e-124	421.0	COG0747@1|root,COG0747@2|Bacteria,2GMMG@201174|Actinobacteria	201174|Actinobacteria	E	extracellular solute-binding protein, family 5	-	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044444,GO:0044464	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_773496_2	479432.Sros_7204	5.566e-170	548.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4EMXZ@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_773496_5	1245475.ANAE01000129_gene1094	2.166e-133	434.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158390_k127_773496_3	479432.Sros_7206	6.065e-164	522.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4EM5E@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_773496_1	479432.Sros_7207	1.961e-179	566.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EM7U@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158390_k127_773496_10	1464048.JNZS01000021_gene2762	3.198e-37	163.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4DBGI@85008|Micromonosporales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158390_k127_773496_8	1121924.ATWH01000010_gene912	3.232e-70	267.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria,4FKBG@85023|Microbacteriaceae	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158390_k127_7759_3	1120950.KB892759_gene6235	4.939e-23	101.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4DRJ7@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158390_k127_7759_2	436308.Nmar_1463	2.366e-38	146.0	COG3324@1|root,arCOG04946@2157|Archaea	436308.Nmar_1463|-	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_7759_1	463191.SSEG_02357	5.144e-51	189.0	COG0346@1|root,COG0346@2|Bacteria,2IIMV@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,TetR_N
SRR25158390_k127_7759_0	1123024.AUII01000016_gene1302	7.113e-77	261.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4E3FT@85010|Pseudonocardiales	201174|Actinobacteria	S	Appr-1'-p processing enzyme	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158390_k127_7759_4	926564.KI911744_gene3839	2.291e-19	92.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4F5Q6@85017|Promicromonosporaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158390_k127_782890_1	42256.RradSPS_0825	1.021e-98	333.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4CQ14@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
SRR25158390_k127_782890_0	1121272.KB903249_gene1627	7.639e-188	595.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158390_k127_790022_0	345341.KUTG_04087	5.19e-202	634.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4E1FM@85010|Pseudonocardiales	201174|Actinobacteria	L	SNF2 family N-terminal domain	helZ	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
SRR25158390_k127_790022_1	471852.Tcur_4213	4.46e-133	430.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4EH3U@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158390_k127_790022_2	2002.JOEQ01000010_gene6247	1.539e-50	184.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4EI8G@85012|Streptosporangiales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_79126_9	1394178.AWOO02000036_gene8885	1.789e-07	52.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EJBR@85012|Streptosporangiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158390_k127_79126_5	1177594.MIC448_2040024	1.081e-106	353.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4FTFQ@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158390_k127_79126_1	1177594.MIC448_480002	1.088e-187	602.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_79126_0	1177594.MIC448_2260009	1.362e-195	624.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4FNAE@85023|Microbacteriaceae	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_79126_4	1068978.AMETH_3144	6.063e-138	450.0	COG0477@1|root,COG2814@2|Bacteria,2GKY3@201174|Actinobacteria,4E01M@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_79126_6	446470.Snas_2716	1.711e-94	317.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,4EZP5@85014|Glycomycetales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
SRR25158390_k127_79126_3	101510.RHA1_ro02832	7.553e-144	466.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4FU8T@85025|Nocardiaceae	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_79126_2	1177594.MIC448_2130002	4.091e-158	509.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_79126_7	1177594.MIC448_2040006	2.431e-70	244.0	2BZD4@1|root,33Y08@2|Bacteria,2GY7R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_79126_8	1120949.KB903357_gene4740	3.797e-28	117.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158390_k127_801221_2	1003195.SCAT_2418	1.306e-192	637.0	COG3225@1|root,COG3225@2|Bacteria,2GMTX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_801221_8	1394178.AWOO02000034_gene8400	5.925e-80	285.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4EHCS@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
SRR25158390_k127_801221_5	1476876.JOJO01000015_gene6197	2.107e-106	367.0	COG2211@1|root,COG2211@2|Bacteria,2I33Q@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_801221_9	1245475.ANAE01000061_gene2500	3.442e-47	188.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4EJAV@85012|Streptosporangiales	201174|Actinobacteria	K	Cold shock protein domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158390_k127_801221_7	1122182.KB903836_gene4848	1.385e-90	305.0	COG1718@1|root,COG1718@2|Bacteria,2GKX1@201174|Actinobacteria,4D9IE@85008|Micromonosporales	201174|Actinobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_801221_11	1210045.ALNP01000016_gene1869	3.994e-35	147.0	2CP0Z@1|root,32SI8@2|Bacteria,2IHXV@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158390_k127_801221_3	1120950.KB892775_gene1193	3.916e-157	509.0	COG0546@1|root,COG1606@1|root,COG0546@2|Bacteria,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria,4DP0G@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,HAD,HAD_2,Hydrolase_like,NAD_synthase,QueC
SRR25158390_k127_801221_1	68260.JOAY01000033_gene2442	1.339e-198	646.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
SRR25158390_k127_801221_6	1120950.KB892717_gene2440	1.111e-104	360.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4DPV3@85009|Propionibacteriales	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158390_k127_801221_0	1123320.KB889723_gene7539	1.604e-296	917.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria	201174|Actinobacteria	L	helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158390_k127_801221_10	345341.KUTG_04521	2.66e-39	160.0	COG3795@1|root,COG3795@2|Bacteria,2IIV2@201174|Actinobacteria,4EBUK@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_801221_4	1150864.MILUP08_43386	6.649e-152	490.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4D92B@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_81016_2	28042.GU90_00660	1.368e-115	381.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4DXPM@85010|Pseudonocardiales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158390_k127_81016_1	1150864.MILUP08_41769	3.451e-207	651.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4D8SG@85008|Micromonosporales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_81016_4	37919.EP51_38425	0.0004679	46.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FTYX@85025|Nocardiaceae	201174|Actinobacteria	IQ	Acyl-CoA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158390_k127_81016_0	928724.SacglDRAFT_03560	5.114e-225	704.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DX8J@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA2	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_81016_3	469371.Tbis_1608	2.445e-84	286.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DY07@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM short chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_827803_2	1380354.JIAN01000005_gene2688	5.925e-47	178.0	2DNEF@1|root,32X3P@2|Bacteria,2GPZ8@201174|Actinobacteria	201174|Actinobacteria	S	SAF	-	-	-	-	-	-	-	-	-	-	-	-	SAF
SRR25158390_k127_827803_1	1380354.JIAN01000005_gene2689	2.452e-80	276.0	COG0455@1|root,COG0455@2|Bacteria,2HT5K@201174|Actinobacteria	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_827803_0	1095767.CAHD01000203_gene2329	1.236e-222	696.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system protein e	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158390_k127_827803_3	1095767.CAHD01000203_gene2330	3.134e-38	149.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria	201174|Actinobacteria	U	type II secretion system	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158390_k127_827861_8	479435.Kfla_3879	2.724e-08	61.0	2EDGM@1|root,32W2W@2|Bacteria,2I8A9@201174|Actinobacteria,4DWJH@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_827861_7	1003195.SCAT_2743	1.394e-42	163.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158390_k127_827861_2	526225.Gobs_1430	1.363e-80	277.0	COG1277@1|root,COG1277@2|Bacteria,2GJ2R@201174|Actinobacteria	201174|Actinobacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158390_k127_827861_0	471852.Tcur_2964	1.46e-136	441.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4EFY4@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_827861_1	1246995.AFR_33260	2.67e-125	415.0	COG0477@1|root,COG2814@2|Bacteria,2GJK6@201174|Actinobacteria,4D8Z4@85008|Micromonosporales	201174|Actinobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRR25158390_k127_827861_4	1229780.BN381_60027	4.991e-63	229.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,3UWWF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158390_k127_827861_5	1121019.AUMN01000004_gene1480	6.367e-49	187.0	COG1309@1|root,COG1309@2|Bacteria,2IKQ8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158390_k127_827861_9	1298860.AUEM01000005_gene2736	2.387e-05	48.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158390_k127_827861_6	1121017.AUFG01000014_gene2002	7.588e-48	185.0	COG1266@1|root,COG1266@2|Bacteria,2IIE6@201174|Actinobacteria,4FF66@85021|Intrasporangiaceae	201174|Actinobacteria	F	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158390_k127_827861_3	1298863.AUEP01000001_gene1078	1.952e-64	225.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4DPQP@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
SRR25158390_k127_829528_4	1123023.JIAI01000005_gene459	2.526e-52	187.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
SRR25158390_k127_829528_0	1033730.CAHG01000007_gene2683	2.821e-285	887.0	COG1960@1|root,COG1960@2|Bacteria,2GJIB@201174|Actinobacteria,4DP6T@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,AcylCoA_DH_N
SRR25158390_k127_829528_3	29306.JOBE01000029_gene2028	9.677e-80	274.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
SRR25158390_k127_829528_2	909613.UO65_2535	2.908e-85	300.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2GJMC@201174|Actinobacteria,4DZ2V@85010|Pseudonocardiales	201174|Actinobacteria	S	Threonine/Serine exporter, ThrE	thrE	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
SRR25158390_k127_829528_8	935866.JAER01000015_gene1641	3.685e-10	64.0	COG3620@1|root,COG3620@2|Bacteria,2GX50@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158390_k127_829528_6	935866.JAER01000015_gene1640	3.55e-33	135.0	COG4679@1|root,COG4679@2|Bacteria,2HDBE@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_829528_7	1385520.N802_05960	8.563e-21	94.0	2DR8X@1|root,33AQM@2|Bacteria,2GSH7@201174|Actinobacteria,4FHTU@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_829528_5	1193181.BN10_900008	1.458e-45	168.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria,4FHBZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_829528_1	479435.Kfla_6088	1.774e-227	711.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4DPEX@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158390_k127_838805_1	1137269.AZWL01000005_gene2184	2.519e-117	383.0	COG4106@1|root,COG4106@2|Bacteria,2GJFS@201174|Actinobacteria	201174|Actinobacteria	S	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_838805_0	1169161.KB897726_gene1431	2.395e-123	401.0	COG4106@1|root,COG4106@2|Bacteria,2GJFS@201174|Actinobacteria	201174|Actinobacteria	S	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158390_k127_838805_2	1120950.KB892759_gene6278	6.791e-61	218.0	COG0318@1|root,COG0318@2|Bacteria,2GIX4@201174|Actinobacteria,4DRZ1@85009|Propionibacteriales	201174|Actinobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158390_k127_838805_3	1121272.KB903249_gene1466	2.356e-32	127.0	COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4DDKJ@85008|Micromonosporales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158390_k127_846201_1	1122138.AQUZ01000001_gene1576	5.99e-184	586.0	COG0166@1|root,COG0166@2|Bacteria,2HZ58@201174|Actinobacteria,4DN42@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GPI family	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158390_k127_846201_0	266940.Krad_2924	9.9e-266	824.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158390_k127_855660_1	446470.Snas_0011	4.095e-66	233.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EXMD@85014|Glycomycetales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158390_k127_855660_2	1380354.JIAN01000008_gene3290	1.233e-25	115.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_855660_0	1123023.JIAI01000001_gene6484	6.485e-255	797.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DZQU@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158390_k127_863782_2	247156.NFA_35110	1.576e-63	232.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4FUS4@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_863782_3	1206732.BAGD01000053_gene1860	5.037e-58	203.0	COG3795@1|root,COG3795@2|Bacteria,2IP2I@201174|Actinobacteria,4G1U1@85025|Nocardiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_863782_0	926550.CLDAP_30940	1.903e-193	615.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158390_k127_863782_1	882083.SacmaDRAFT_1561	8e-129	422.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DXNB@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158390_k127_8689_4	1210046.B277_06659	1.5e-08	60.0	COG4096@1|root,COG4096@2|Bacteria,2I2FC@201174|Actinobacteria,4FFWC@85021|Intrasporangiaceae	201174|Actinobacteria	L	EcoEI R protein C-terminal	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
SRR25158390_k127_8689_5	1122138.AQUZ01000074_gene7306	1.147e-05	57.0	2B82C@1|root,321A9@2|Bacteria,2H58Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_8689_2	1120950.KB892784_gene168	1.717e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,2GP2X@201174|Actinobacteria,4DUKA@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_8689_0	1121272.KB903290_gene4688	1.439e-108	360.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158390_k127_8689_3	68170.KL590533_gene5260	6.995e-54	205.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4E1XJ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158390_k127_8689_1	1121019.AUMN01000005_gene2712	2.319e-69	256.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158390_k127_875171_0	1246448.ANAZ01000011_gene592	3.951e-270	840.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158390_k127_875171_10	706587.Desti_3688	7.587e-31	125.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,43BFQ@68525|delta/epsilon subdivisions,2X6U4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	pfam fad	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158390_k127_875171_3	1246448.ANAZ01000011_gene591	2.328e-198	623.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria,4EI8Y@85012|Streptosporangiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_875171_9	345341.KUTG_00773	1.92e-70	241.0	COG3832@1|root,COG3832@2|Bacteria,2IFRJ@201174|Actinobacteria,4E53D@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_875171_1	1214101.BN159_4293	1.049e-236	741.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
SRR25158390_k127_875171_6	196162.Noca_4917	3.508e-110	364.0	COG1073@1|root,COG1073@2|Bacteria,2I364@201174|Actinobacteria,4DWZC@85009|Propionibacteriales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_875171_5	1214101.BN159_4291	4.321e-123	400.0	COG0596@1|root,COG0596@2|Bacteria,2IACG@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_875171_8	1463825.JNXC01000014_gene7630	2.569e-72	248.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria,4E3IE@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158390_k127_875171_4	935839.JAGJ01000001_gene970	6.107e-181	580.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4F4Q9@85017|Promicromonosporaceae	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_875171_7	102129.Lepto7375DRAFT_1337	5.05e-89	308.0	COG0520@1|root,COG0520@2|Bacteria,1G87Y@1117|Cyanobacteria	1117|Cyanobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_875171_12	1121019.AUMN01000015_gene3723	3.356e-07	60.0	2C5ND@1|root,3053S@2|Bacteria,2GSG7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_875171_2	1463920.JOGB01000070_gene5757	1.913e-235	734.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158390_k127_875242_5	1449976.KALB_1602	6.194e-15	77.0	COG4118@1|root,COG4118@2|Bacteria,2IR4E@201174|Actinobacteria,4E5XV@85010|Pseudonocardiales	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158390_k127_875242_4	1906.SFRA_31640	9.569e-33	135.0	COG1487@1|root,COG1487@2|Bacteria,2IM11@201174|Actinobacteria	201174|Actinobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_875242_3	670292.JH26_27120	1.904e-47	175.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2U5QW@28211|Alphaproteobacteria,1JV7J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Phenylacetic acid degradation protein PaaD	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRR25158390_k127_875242_1	1906.SFRA_16660	1.625e-141	465.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158390_k127_875242_0	196162.Noca_4493	9.619e-239	750.0	COG1012@1|root,COG1012@2|Bacteria,2GNJJ@201174|Actinobacteria,4DQ0E@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158390_k127_875242_2	1463845.JOIG01000002_gene2283	6.573e-116	380.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158390_k127_881263_1	110319.CF8_0207	2.155e-145	479.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DPA4@85009|Propionibacteriales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158390_k127_881263_0	1464048.JNZS01000027_gene1927	2.041e-255	799.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4DCJX@85008|Micromonosporales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158390_k127_881263_3	994479.GL877880_gene3715	8.523e-75	257.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4E33I@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158390_k127_881263_8	1122933.JNIY01000003_gene1133	2.784e-13	78.0	2EJQU@1|root,33DFN@2|Bacteria,2IHQ3@201174|Actinobacteria,4F1CH@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_881263_4	1380354.JIAN01000007_gene28	4.246e-62	223.0	COG0265@1|root,COG0265@2|Bacteria,2HXVH@201174|Actinobacteria,4F14S@85016|Cellulomonadaceae	201174|Actinobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158390_k127_881263_5	593907.Celgi_2644	2.955e-48	180.0	28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4F216@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_881263_6	443255.SCLAV_3119	4.754e-48	175.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158390_k127_881263_2	570268.ANBB01000064_gene983	6.055e-124	415.0	COG1409@1|root,COG1409@2|Bacteria,2I59J@201174|Actinobacteria,4EHR8@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158390_k127_881263_9	1123024.AUII01000051_gene639	3.807e-11	76.0	COG0582@1|root,COG0582@2|Bacteria,2I9QS@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Phage_int_SAM_5,Phage_integrase
SRR25158390_k127_881263_11	675635.Psed_6086	3.399e-05	52.0	COG0582@1|root,COG2188@1|root,COG0582@2|Bacteria,COG2188@2|Bacteria,2I9QS@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158390_k127_881263_10	1449353.JQMQ01000005_gene1143	1.638e-09	65.0	COG0382@1|root,COG0382@2|Bacteria,2HQKP@201174|Actinobacteria,2NM6V@228398|Streptacidiphilus	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158390_k127_881263_7	1120950.KB892720_gene1817	3.473e-23	100.0	COG4978@1|root,COG4978@2|Bacteria,2IKYA@201174|Actinobacteria,4DRWX@85009|Propionibacteriales	201174|Actinobacteria	KT	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR25158390_k127_889557_9	1123321.KB905814_gene2234	6.879e-11	62.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158390_k127_889557_3	247639.MGP2080_14376	1.134e-130	432.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RYMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_889557_4	1463920.JOGB01000059_gene3956	3.207e-123	402.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158390_k127_889557_7	436229.JOEH01000001_gene1528	8.137e-82	280.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,2NGFI@228398|Streptacidiphilus	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_889557_1	929712.KI912613_gene1192	1.043e-137	453.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPR1@84995|Rubrobacteria	84995|Rubrobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158390_k127_889557_8	649831.L083_4287	6.23e-23	107.0	2EDJR@1|root,337FI@2|Bacteria,2GIRI@201174|Actinobacteria,4DIZB@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_889557_6	710111.FraQA3DRAFT_5458	7.08e-84	282.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4ESDQ@85013|Frankiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158390_k127_889557_2	136273.GY22_00995	3.249e-135	437.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,1WAHN@1268|Micrococcaceae	201174|Actinobacteria	F	Formyl transferase	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SRR25158390_k127_889557_5	136273.GY22_01000	1.163e-109	362.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria,1W7V3@1268|Micrococcaceae	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158390_k127_889557_0	1276920.ADIAG_03234	6.181e-250	776.0	COG0404@1|root,COG0404@2|Bacteria,2GPU4@201174|Actinobacteria,1W8JS@1268|Micrococcaceae	201174|Actinobacteria	E	Aminomethyltransferase folate-binding domain	-	-	2.1.1.341	ko:K15066	ko00627,ko01120,map00627,map01120	-	R09271,R10136	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158390_k127_891538_0	471852.Tcur_4063	4.55e-129	417.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4EGWS@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158390_k127_891538_3	67315.JOBD01000025_gene1435	3.139e-16	85.0	COG2835@1|root,COG2835@2|Bacteria,2GQPR@201174|Actinobacteria	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158390_k127_891538_1	1120950.KB892759_gene6293	1.266e-93	319.0	COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4DMZS@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR25158390_k127_891538_2	656024.FsymDg_2711	2.786e-42	160.0	COG1848@1|root,COG1848@2|Bacteria,2GSP5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158390_k127_899815_1	1121935.AQXX01000144_gene4400	1.945e-75	276.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,1XIA4@135619|Oceanospirillales	135619|Oceanospirillales	D	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,LTD
SRR25158390_k127_899815_2	1179773.BN6_46660	1.263e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4E5FV@85010|Pseudonocardiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_899815_3	471853.Bcav_0166	7.993e-55	195.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158390_k127_899815_0	926564.KI911665_gene627	0.0	1621.0	COG1404@1|root,COG3979@1|root,COG1404@2|Bacteria,COG3979@2|Bacteria,2GK3D@201174|Actinobacteria,4F5NW@85017|Promicromonosporaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
SRR25158390_k127_899815_4	446470.Snas_5343	5.613e-25	124.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SRR25158390_k127_901720_2	1146883.BLASA_3621	1.796e-210	658.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4EREZ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158390_k127_901720_9	1463821.JOGR01000010_gene3879	1.478e-77	267.0	COG0662@1|root,COG0662@2|Bacteria,2I83H@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_901720_8	1237500.ANBA01000027_gene2011	3.356e-119	393.0	COG0673@1|root,COG0673@2|Bacteria,2H6HX@201174|Actinobacteria,4EIQ1@85012|Streptosporangiales	201174|Actinobacteria	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
SRR25158390_k127_901720_4	1463856.JOHY01000026_gene3804	4.979e-159	509.0	COG0673@1|root,COG0673@2|Bacteria,2GM7J@201174|Actinobacteria	201174|Actinobacteria	K	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_901720_0	66874.JOFS01000023_gene1510	3.64e-305	955.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349,ko:K17641	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158390_k127_901720_1	590998.Celf_0574	1.421e-264	854.0	COG0726@1|root,COG3693@1|root,COG0726@2|Bacteria,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,CBM_2,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1
SRR25158390_k127_901720_6	1123065.ATWL01000006_gene2248	1.808e-150	482.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
SRR25158390_k127_901720_7	471853.Bcav_3324	3.317e-120	417.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
SRR25158390_k127_901720_3	471853.Bcav_3323	5.576e-188	602.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_901720_10	743718.Isova_0461	2.564e-69	242.0	COG5578@1|root,COG5578@2|Bacteria,2I6GS@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
SRR25158390_k127_901720_5	33876.JNXY01000026_gene3457	4.204e-158	504.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DA7N@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional	bxlR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158390_k127_905628_8	479435.Kfla_2380	7.698e-50	182.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4DN5C@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158390_k127_905628_12	1121946.AUAX01000009_gene4524	1.25e-27	119.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4DF07@85008|Micromonosporales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158390_k127_905628_9	455632.SGR_693	7.977e-48	176.0	COG2337@1|root,COG2337@2|Bacteria,2GM10@201174|Actinobacteria,41AGD@629295|Streptomyces griseus group	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
SRR25158390_k127_905628_0	1048339.KB913029_gene4817	0.0	1008.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4ERZ3@85013|Frankiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158390_k127_905628_1	405948.SACE_5343	1.29e-250	790.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DY4J@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158390_k127_905628_2	1120950.KB892739_gene4000	2.132e-185	587.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DN32@85009|Propionibacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158390_k127_905628_5	561175.KB894094_gene1638	1.776e-107	358.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,4EFY9@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
SRR25158390_k127_905628_4	1120950.KB892739_gene3996	1.869e-137	460.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4DP2Y@85009|Propionibacteriales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR25158390_k127_905628_3	1123320.KB889675_gene4102	1.542e-163	524.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158390_k127_905628_6	58123.JOFJ01000001_gene3330	9.122e-85	288.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4EFJ8@85012|Streptosporangiales	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158390_k127_905628_10	675635.Psed_5740	1.914e-45	183.0	COG5401@1|root,COG5401@2|Bacteria,2IQ3Y@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158390_k127_905628_7	1237500.ANBA01000009_gene1432	1.329e-53	197.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4EGWT@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_905628_11	1120971.AUCA01000004_gene1302	1.745e-30	125.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,27A28@186823|Alicyclobacillaceae	91061|Bacilli	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158390_k127_913376_1	994479.GL877879_gene5777	5.179e-55	203.0	COG3858@1|root,COG3858@2|Bacteria,2HZ7I@201174|Actinobacteria,4E92I@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158390_k127_913376_0	1246474.ANBE01000021_gene3975	1.004e-108	366.0	COG1215@1|root,COG1215@2|Bacteria,2I97V@201174|Actinobacteria,4EQF1@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158390_k127_915385_0	1003195.SCAT_1288	6.443e-206	646.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158390_k127_915385_1	875328.JDM601_0672	1.155e-47	175.0	COG2337@1|root,COG2337@2|Bacteria,2IR5D@201174|Actinobacteria,23AAR@1762|Mycobacteriaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158390_k127_915385_2	1157632.AQWQ01000009_gene2892	4.961e-13	68.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158390_k127_923915_0	1089551.KE386572_gene3210	1.451e-296	914.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria,4BSBA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Carbohydrate ABC transporter substrate-binding protein, CUT1 family	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_92415_4	882082.SaccyDRAFT_0237	5.232e-57	209.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4E2DH@85010|Pseudonocardiales	201174|Actinobacteria	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158390_k127_92415_2	1123258.AQXZ01000019_gene3368	4.061e-162	518.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4FYT4@85025|Nocardiaceae	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158390_k127_92415_0	1146883.BLASA_4736	0.0	1045.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4ES3C@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158390_k127_92415_3	469371.Tbis_1347	5.088e-65	226.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria,4E4RB@85010|Pseudonocardiales	201174|Actinobacteria	S	YbaK prolyl-tRNA	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158390_k127_92415_1	1122611.KB903948_gene6637	7.551e-206	656.0	COG1012@1|root,COG1012@2|Bacteria,2GNM8@201174|Actinobacteria,4EG5U@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.4	ko:K14519	ko00930,ko01100,ko01120,ko01220,map00930,map01100,map01120,map01220	-	R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_92415_5	1120950.KB892790_gene2132	2.294e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,2IM6Y@201174|Actinobacteria,4DR7P@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158390_k127_92415_6	1206732.BAGD01000053_gene1892	3.048e-19	88.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4FUBG@85025|Nocardiaceae	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158390_k127_937998_2	928724.SacglDRAFT_01205	3.58e-71	243.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4E3MA@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM redox-sensitive transcriptional activator SoxR	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158390_k127_937998_4	479431.Namu_0699	1.887e-46	181.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,Big_5,Exo_endo_phos,LTD,SdiA-regulated,VPEP
SRR25158390_k127_937998_1	1120950.KB892784_gene208	5.56e-176	567.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4DTSU@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158390_k127_937998_0	196162.Noca_3657	1.347e-177	562.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4DP6P@85009|Propionibacteriales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158390_k127_937998_6	1306174.JODP01000006_gene3617	3.924e-31	136.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria	201174|Actinobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158390_k127_937998_3	1120950.KB892784_gene197	2.858e-66	232.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4DQ98@85009|Propionibacteriales	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158390_k127_937998_5	469371.Tbis_0611	7.274e-37	141.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4E4AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised P-loop hydrolase UPF0079	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158390_k127_955077_0	1120950.KB892739_gene3932	1.052e-230	731.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4DN6K@85009|Propionibacteriales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158390_k127_955077_1	935866.JAER01000017_gene4394	1.372e-210	658.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria,4DNDR@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158390_k127_955077_2	1385518.N798_02060	1.123e-178	567.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4FEVC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158390_k127_955077_3	1463845.JOIG01000005_gene3262	2.742e-144	473.0	COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria	201174|Actinobacteria	G	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158390_k127_955077_4	43354.JOIJ01000008_gene2966	2.007e-92	306.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4E055@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158390_k127_976599_1	1298863.AUEP01000001_gene885	8.78e-124	399.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DN0N@85009|Propionibacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158390_k127_976599_2	1394178.AWOO02000022_gene7216	2.215e-36	142.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4EK8U@85012|Streptosporangiales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158390_k127_976599_0	67257.JODR01000008_gene3435	4.297e-163	521.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158390_k127_981027_8	1120950.KB892745_gene2870	1.714e-114	381.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4DPQZ@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158390_k127_981027_9	345341.KUTG_05243	5.053e-103	342.0	COG0697@1|root,COG0697@2|Bacteria,2GNSA@201174|Actinobacteria,4E396@85010|Pseudonocardiales	201174|Actinobacteria	EG	DMT(Drug metabolite transporter) superfamily permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_981027_7	1172185.KB911530_gene3434	4.209e-116	380.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4FXPU@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158390_k127_981027_23	1380347.JNII01000007_gene589	4.731e-09	65.0	COG5336@1|root,COG5336@2|Bacteria,2GWR5@201174|Actinobacteria	201174|Actinobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158390_k127_981027_14	935866.JAER01000009_gene654	1.346e-74	259.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4DPUV@85009|Propionibacteriales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158390_k127_981027_22	1306174.JODP01000018_gene4426	2.887e-20	103.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158390_k127_981027_18	1050202.KB913024_gene2545	2.09e-44	169.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,408JW@622450|Actinopolysporales	201174|Actinobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158390_k127_981027_15	1449976.KALB_7610	9.327e-56	205.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4DXBG@85010|Pseudonocardiales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRR25158390_k127_981027_0	1122611.KB903996_gene7572	1.159e-266	831.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4EG2U@85012|Streptosporangiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158390_k127_981027_11	1048339.KB913029_gene3397	1.052e-97	328.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4ERNM@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158390_k127_981027_1	471852.Tcur_3916	2.017e-236	744.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4EG3U@85012|Streptosporangiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158390_k127_981027_20	73044.JNXP01000009_gene2908	7.559e-34	134.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158390_k127_981027_21	1120950.KB892745_gene2881	2.904e-26	113.0	2E6YX@1|root,331I5@2|Bacteria,2IFIG@201174|Actinobacteria,4DRJC@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2550)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2550
SRR25158390_k127_981027_3	1120950.KB892745_gene2885	3.349e-173	552.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DND6@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158390_k127_981027_10	1206726.BAFV01000039_gene2696	3.903e-101	340.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria,4FWWC@85025|Nocardiaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158390_k127_981027_6	446470.Snas_1842	2.804e-125	406.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4EXNX@85014|Glycomycetales	201174|Actinobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase NAD-binding	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158390_k127_981027_12	55952.BU52_07110	2.954e-91	307.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158390_k127_981027_19	1348338.ADILRU_0375	8.922e-44	169.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4FPNK@85023|Microbacteriaceae	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158390_k127_981027_17	1304865.JAGF01000001_gene1411	1.741e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158390_k127_981027_16	1380393.JHVP01000011_gene3070	4.265e-49	184.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158390_k127_981027_5	1246995.AFR_00900	3.264e-141	463.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4D8MY@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158390_k127_981027_2	1278078.G419_20105	3.785e-212	682.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4FW6E@85025|Nocardiaceae	201174|Actinobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158390_k127_981027_4	1445613.JALM01000009_gene719	7.223e-166	543.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,2GJS0@201174|Actinobacteria,4DYE7@85010|Pseudonocardiales	201174|Actinobacteria	S	NAD- dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158390_k127_981027_13	35754.JNYJ01000035_gene3983	1.231e-75	267.0	COG0524@1|root,COG0524@2|Bacteria,2GMD4@201174|Actinobacteria,4DD21@85008|Micromonosporales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158390_k127_981027_24	1121272.KB903249_gene1442	3.057e-07	58.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,4DEV6@85008|Micromonosporales	201174|Actinobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
## 4121 queries scanned
## Total time (seconds): 8.386351108551025
## Rate: 491.39 q/s