## Thu Feb 19 04:49:15 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158390_bin.34.fa -m mmseqs --output SRR25158390_bin.34 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158390_bin.34 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158390_k127_1006631_8	1459636.NTE_02849	4.346e-07	54.0	COG4257@1|root,arCOG06267@1|root,arCOG03564@2157|Archaea,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	651137|Thaumarchaeota	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158390_k127_1006631_6	1459636.NTE_00810	5.639e-16	85.0	arCOG08825@1|root,arCOG08825@2157|Archaea	1459636.NTE_00810|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1006631_1	1459636.NTE_01727	2e-81	278.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_1006631_10	1229909.NSED_06995	0.0001347	51.0	COG4250@1|root,arCOG02910@2157|Archaea	2157|Archaea	T	Sensory domain in DIguanylate Cyclases and Two-component system	-	-	-	-	-	-	-	-	-	-	-	-	DICT
SRR25158390_k127_1006631_0	1459636.NTE_03261	3.348e-94	317.0	COG1230@1|root,arCOG01477@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_1006631_4	469382.Hbor_12790	4.285e-22	102.0	COG0529@1|root,arCOG01040@2157|Archaea,2XWW4@28890|Euryarchaeota,23V8B@183963|Halobacteria	183963|Halobacteria	P	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
SRR25158390_k127_1006631_2	1459636.NTE_00888	5.808e-27	115.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_1006631_9	1232437.KL662077_gene1961	1.183e-05	49.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,42MW8@68525|delta/epsilon subdivisions,2WKI6@28221|Deltaproteobacteria,2MIK1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_10159_0	1459636.NTE_00201	1.119e-57	208.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_1017798_0	485913.Krac_2159	5.353e-181	581.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	acpA	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158390_k127_1017798_4	1459636.NTE_03225	7.725e-68	235.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_1017798_5	931626.Awo_c07350	4.454e-55	205.0	COG0596@1|root,COG0596@2|Bacteria,1VRHA@1239|Firmicutes,24PCH@186801|Clostridia	186801|Clostridia	S	Hydrolase, alpha beta domain protein	mhpC	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158390_k127_1017798_2	886293.Sinac_1873	4.859e-108	354.0	COG1028@1|root,COG1028@2|Bacteria,2IZED@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_1017798_6	1459636.NTE_00446	2.249e-28	116.0	COG0640@1|root,arCOG01681@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158390_k127_1017798_8	509635.N824_01130	1.816e-10	68.0	COG3832@1|root,COG3832@2|Bacteria,4NST9@976|Bacteroidetes,1ISQV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158390_k127_1017798_3	1028800.RG540_CH39100	5.712e-93	310.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,4BDVS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158390_k127_1017798_1	1459636.NTE_00977	6.588e-120	391.0	COG0010@1|root,arCOG01700@2157|Archaea	2157|Archaea	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_1049349_1	1459636.NTE_02510	4.573e-62	222.0	arCOG02103@1|root,arCOG02103@2157|Archaea,41T51@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF4443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4443
SRR25158390_k127_1049349_2	1229909.NSED_04935	4.576e-21	94.0	arCOG08746@1|root,arCOG08746@2157|Archaea,41SWA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
SRR25158390_k127_1049349_0	436308.Nmar_0878	1.1e-62	223.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
SRR25158390_k127_1049349_3	1123296.JQKE01000130_gene1250	4.303e-18	92.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KQRJ@206351|Neisseriales	206351|Neisseriales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158390_k127_107524_8	1459636.NTE_00401	3.078e-11	64.0	COG1794@1|root,arCOG02005@2157|Archaea,41SM4@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158390_k127_107524_6	1131266.ARWQ01000005_gene849	2.368e-29	123.0	COG0454@1|root,arCOG00826@2157|Archaea,41T2E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
SRR25158390_k127_107524_1	1459636.NTE_00043	5.393e-122	396.0	COG1117@1|root,arCOG00231@2157|Archaea,41SYJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158390_k127_107524_2	1459636.NTE_02295	1.199e-88	299.0	COG2897@1|root,arCOG02019@2157|Archaea,41SXR@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158390_k127_107524_3	1459636.NTE_03156	5.616e-77	269.0	COG0677@1|root,arCOG00252@2157|Archaea	2157|Archaea	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	NAD_binding_2,UDPG_MGDP_dh,UDPG_MGDP_dh_C
SRR25158390_k127_107524_4	1459636.NTE_01294	9.861e-49	182.0	COG0586@1|root,arCOG03117@2157|Archaea,41SQ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158390_k127_107524_5	1459636.NTE_00433	6.589e-39	151.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_107524_0	1459636.NTE_03097	3.112e-151	491.0	arCOG03664@1|root,arCOG03664@2157|Archaea	2157|Archaea	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3
SRR25158390_k127_1172085_0	1146883.BLASA_2956	3.469e-14	86.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,4EUTU@85013|Frankiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158390_k127_1196370_10	1459636.NTE_02021	2.286e-65	232.0	COG2263@1|root,arCOG00910@2157|Archaea,41S85@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196370_3	1459636.NTE_02033	1.871e-153	488.0	COG0074@1|root,arCOG01339@2157|Archaea,41SEU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158390_k127_1196370_4	1459636.NTE_02034	7.767e-153	490.0	COG0045@1|root,arCOG01337@2157|Archaea,41S5M@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158390_k127_1196370_5	1459636.NTE_01075	3.452e-152	488.0	COG0162@1|root,arCOG01886@2157|Archaea,41S8C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Tyrosine--tRNA ligase	-	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
SRR25158390_k127_1196370_6	1459636.NTE_00916	8.986e-143	456.0	COG1010@1|root,arCOG00647@2157|Archaea,41S6W@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158390_k127_1196370_2	1459636.NTE_00933	4.29e-182	580.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
SRR25158390_k127_1196370_7	1459636.NTE_00934	1.325e-115	376.0	COG0592@1|root,arCOG00488@2157|Archaea,41S6E@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
SRR25158390_k127_1196370_13	1459636.NTE_00945	4.646e-34	134.0	COG1594@1|root,arCOG00579@2157|Archaea,41SS3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	-	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	TFIIS_C
SRR25158390_k127_1196370_16	1459636.NTE_00946	3.153e-20	93.0	COG1761@1|root,arCOG04111@2157|Archaea,41SV9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb3/Rpb11 dimerisation domain	-	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
SRR25158390_k127_1196370_12	1459636.NTE_00947	3.593e-46	172.0	arCOG08749@1|root,arCOG08749@2157|Archaea,41SRV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196370_18	1459636.NTE_03029	1.284e-13	72.0	arCOG08748@1|root,arCOG08748@2157|Archaea,41SV7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196370_1	1459636.NTE_02976	6.65e-192	607.0	COG0017@1|root,arCOG00407@2157|Archaea	2157|Archaea	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158390_k127_1196370_8	1459636.NTE_01196	1.185e-107	354.0	COG4742@1|root,arCOG04362@2157|Archaea,41SGE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1196370_14	1459636.NTE_01195	3.436e-31	123.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196370_21	1459636.NTE_01194	0.0002033	46.0	arCOG08679@1|root,arCOG08679@2157|Archaea	2157|Archaea	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196370_9	1459636.NTE_01193	7.961e-100	335.0	COG0071@1|root,COG0705@1|root,arCOG01768@2157|Archaea,arCOG01833@2157|Archaea,41SKD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158390_k127_1196370_20	309800.C498_08555	2.314e-08	63.0	COG0723@1|root,arCOG01720@2157|Archaea,2XUXF@28890|Euryarchaeota,23U4Y@183963|Halobacteria	183963|Halobacteria	C	COG0723 Rieske Fe-S protein	-	-	-	ko:K15878	-	-	-	-	ko00000	-	-	-	Rieske
SRR25158390_k127_1196370_0	1459636.NTE_01577	7.991e-249	776.0	COG1290@1|root,arCOG01721@2157|Archaea,41SDA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR25158390_k127_1196370_11	1459636.NTE_03525	4.936e-49	179.0	COG3794@1|root,arCOG02926@2157|Archaea,41SPG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158390_k127_1196370_15	1459636.NTE_01575	1.675e-30	124.0	arCOG08633@1|root,arCOG08633@2157|Archaea,41SUK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196381_2	694430.Natoc_3899	8.426e-22	104.0	arCOG03919@1|root,arCOG03919@2157|Archaea,2XUDK@28890|Euryarchaeota,23TJR@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRR25158390_k127_1196381_9	1459636.NTE_02899	0.0002024	51.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K03294,ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6,2.A.3.2	-	-	Usp
SRR25158390_k127_1196381_1	1459636.NTE_01054	1.195e-33	132.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158390_k127_1196381_4	436308.Nmar_1498	2.394e-15	81.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196381_3	1459636.NTE_00004	2.735e-16	87.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158390_k127_1196381_8	1459636.NTE_00005	3.452e-06	52.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196381_6	1459636.NTE_00006	1.528e-11	68.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1196381_0	1459636.NTE_00007	1.588e-221	710.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
SRR25158390_k127_1202197_2	248742.XP_005649230.1	2.992e-13	81.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158390_k127_1202197_1	378806.STAUR_4005	2.785e-27	126.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1202197_3	1348635.BBJY01000003_gene3938	8.592e-08	59.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XTQN@135623|Vibrionales	135623|Vibrionales	M	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PKD,PPC,Peptidase_S8
SRR25158390_k127_1202197_0	1167006.UWK_03221	4.531e-29	126.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria,2MNAP@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Hemolysin-type calcium-binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HCBP_related,He_PIG,HemolysinCabind,Peptidase_M91,VWA_2
SRR25158390_k127_1205874_13	1459636.NTE_01164	8.838e-24	105.0	arCOG00144@1|root,arCOG11894@1|root,arCOG00144@2157|Archaea,arCOG11894@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_1205874_8	1459636.NTE_00142	1.84e-59	214.0	COG1926@1|root,arCOG06847@2157|Archaea	2157|Archaea	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158390_k127_1205874_5	1131266.ARWQ01000002_gene603	2.01e-75	263.0	arCOG01792@1|root,arCOG01792@2157|Archaea,41SFY@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158390_k127_1205874_0	1459636.NTE_03132	3.151e-135	439.0	COG0715@1|root,arCOG01803@2157|Archaea,41SG5@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158390_k127_1205874_19	1459636.NTE_01035	0.0001603	46.0	COG0640@1|root,COG1809@1|root,arCOG00394@2157|Archaea,arCOG04896@2157|Archaea	2157|Archaea	K	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158390_k127_1205874_7	632335.Calkr_1166	2.065e-66	235.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,42G6K@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158390_k127_1205874_3	1459636.NTE_03130	1.581e-101	337.0	COG0600@1|root,arCOG00169@2157|Archaea,41SIT@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158390_k127_1205874_1	1459636.NTE_01035	1.874e-115	381.0	COG0640@1|root,COG1809@1|root,arCOG00394@2157|Archaea,arCOG04896@2157|Archaea	2157|Archaea	K	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158390_k127_1205874_10	1459636.NTE_00419	3.329e-47	180.0	COG2968@1|root,arCOG04715@2157|Archaea,41T6R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158390_k127_1205874_2	1459636.NTE_03163	2.334e-104	351.0	COG0003@1|root,COG0071@1|root,arCOG01833@2157|Archaea,arCOG02849@2157|Archaea	2157|Archaea	P	Arsenite-activated ATPase ArsA	arsA4	-	3.6.3.16	ko:K01551,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000,ko02000,ko03110	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158390_k127_1205874_15	1459636.NTE_02332	1.198e-19	99.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1205874_16	102129.Lepto7375DRAFT_7767	2.346e-19	93.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158390_k127_1205874_4	436308.Nmar_0735	5.861e-93	323.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1205874_11	1121430.JMLG01000002_gene1312	4.954e-47	177.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,2623X@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158390_k127_1205874_18	913865.DOT_2970	4.664e-12	71.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158390_k127_1205874_6	1123386.AUIW01000011_gene1923	4.233e-71	262.0	COG0433@1|root,COG0433@2|Bacteria,1WME2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1205874_17	1120966.AUBU01000002_gene2349	9.679e-17	86.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158390_k127_1205874_9	1459636.NTE_02436	1.094e-58	217.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
SRR25158390_k127_1205874_12	1459636.NTE_00935	9.792e-30	123.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_1224355_2	1459636.NTE_00198	4.499e-24	104.0	arCOG06947@1|root,arCOG06947@2157|Archaea,41TAK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1224355_1	436308.Nmar_1457	5.129e-127	415.0	arCOG01778@1|root,arCOG01778@2157|Archaea,41SXW@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_1224355_0	1459636.NTE_03481	4.838e-172	561.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158390_k127_1224355_4	1247649.D560_0093	6.857e-07	53.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158390_k127_1224355_3	1123296.JQKE01000032_gene1688	1.27e-12	77.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KPPX@206351|Neisseriales	206351|Neisseriales	Q	Type I secretion target GGXGXDXXX repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,LysM
SRR25158390_k127_1258264_2	1459636.NTE_02001	4.241e-95	316.0	COG1131@1|root,arCOG00194@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_1258264_3	436308.Nmar_0884	1.28e-28	123.0	arCOG10557@1|root,arCOG10557@2157|Archaea,41T1I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1258264_1	1459636.NTE_00030	7.297e-116	382.0	COG1819@1|root,arCOG01393@2157|Archaea,41T16@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
SRR25158390_k127_1258264_0	1459636.NTE_00019	7.242e-136	441.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158390_k127_1268868_0	1459636.NTE_02333	7.055e-12	71.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1268868_1	1122138.AQUZ01000019_gene8188	2.856e-09	58.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158390_k127_1286551_1	67267.JNXT01000041_gene5576	0.0001754	45.0	COG5555@1|root,COG5555@2|Bacteria,2GKZ9@201174|Actinobacteria	201174|Actinobacteria	N	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
SRR25158390_k127_1286551_0	1459636.NTE_02647	3.341e-08	56.0	COG1051@1|root,arCOG01075@2157|Archaea	2157|Archaea	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158390_k127_1288504_0	304371.MCP_0773	5.956e-92	309.0	COG0451@1|root,arCOG01369@2157|Archaea,2Y7SY@28890|Euryarchaeota	28890|Euryarchaeota	M	Epimerase dehydratase	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158390_k127_1289853_1	338963.Pcar_2488	1.495e-59	211.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,43UXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158390_k127_1289853_0	436308.Nmar_1695	7.875e-117	384.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158390_k127_1289853_2	436308.Nmar_0204	5.799e-32	131.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1307849_0	868131.MSWAN_1638	4.698e-07	52.0	arCOG08550@1|root,arCOG08550@2157|Archaea	2157|Archaea	T	Putative antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	VAPB_antitox
SRR25158390_k127_13138_1	1459636.NTE_01853	1.491e-153	491.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
SRR25158390_k127_13138_7	1459636.NTE_01851	1.349e-59	215.0	COG0730@1|root,arCOG02050@2157|Archaea,41SKY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_13138_0	1459636.NTE_01087	0.0	1058.0	COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_13138_11	1459636.NTE_02437	3.28e-22	97.0	COG1552@1|root,arCOG04049@2157|Archaea,41T87@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL40 family	-	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
SRR25158390_k127_13138_6	1459636.NTE_03057	4.475e-61	216.0	COG0237@1|root,arCOG01045@2157|Archaea,41SI8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17
SRR25158390_k127_13138_10	1459636.NTE_03058	6.502e-31	126.0	COG1931@1|root,arCOG01043@2157|Archaea,41SRJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0201 family	-	-	-	ko:K09736	-	-	-	-	ko00000	-	-	-	RNA_binding
SRR25158390_k127_13138_3	1459636.NTE_01328	2.614e-90	301.0	COG0778@1|root,arCOG00288@2157|Archaea,41T1J@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_13138_12	1459636.NTE_01445	1.939e-20	97.0	arCOG08754@1|root,arCOG08754@2157|Archaea,41SUV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_13138_17	1229909.NSED_05710	6.521e-07	58.0	arCOG06343@1|root,arCOG06343@2157|Archaea,41SRX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
SRR25158390_k127_13138_2	1459636.NTE_01626	5.289e-147	473.0	COG3243@1|root,arCOG06344@2157|Archaea,41SEX@651137|Thaumarchaeota	651137|Thaumarchaeota	I	TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_13138_9	1459636.NTE_00560	1.966e-35	138.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_13138_13	1459636.NTE_00367	6.7e-17	85.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_00367|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_13138_14	1459636.NTE_02136	1.646e-14	75.0	arCOG12348@1|root,arCOG12348@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_13138_16	1459636.NTE_01266	4.96e-07	55.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_13138_4	1459636.NTE_00139	7.591e-86	299.0	COG0438@1|root,arCOG04796@2157|Archaea,41T9D@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158390_k127_13138_5	1459636.NTE_01571	3.297e-75	260.0	COG0596@1|root,arCOG01653@2157|Archaea	2157|Archaea	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158390_k127_13138_8	1459636.NTE_02444	9.256e-40	159.0	arCOG01214@1|root,arCOG01214@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,Trehalose_PPase
SRR25158390_k127_1321070_0	679926.Mpet_2328	1.558e-27	121.0	COG3039@1|root,arCOG02751@2157|Archaea,2XTDW@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_1321070_1	926569.ANT_13930	1.096e-05	50.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
SRR25158390_k127_1332506_0	1459636.NTE_02809	1.167e-192	608.0	COG1915@1|root,arCOG04422@2157|Archaea,41SBQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR25158390_k127_1332506_7	1459636.NTE_02808	5.759e-40	150.0	arCOG08655@1|root,arCOG08655@2157|Archaea,41SR9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1332506_6	1459636.NTE_02807	1.812e-41	158.0	COG1896@1|root,arCOG04311@2157|Archaea,41SQE@651137|Thaumarchaeota	651137|Thaumarchaeota	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158390_k127_1332506_5	1459636.NTE_02804	2.361e-53	193.0	COG2096@1|root,arCOG00489@2157|Archaea,41T2I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158390_k127_1332506_8	1459636.NTE_01238	9.694e-38	143.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01238|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1332506_4	1459636.NTE_01333	4.01e-59	216.0	arCOG08708@1|root,arCOG08708@2157|Archaea,41SPK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1332506_1	1459636.NTE_01317	1.659e-182	578.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_1332506_3	1459636.NTE_03272	6.74e-97	327.0	COG1527@1|root,arCOG02459@2157|Archaea,41T18@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (C/AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SRR25158390_k127_1332506_9	1459636.NTE_00455	3.408e-19	91.0	COG2811@1|root,arCOG03363@2157|Archaea,41TA7@651137|Thaumarchaeota	651137|Thaumarchaeota	C	H subunit	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
SRR25158390_k127_1332506_2	1459636.NTE_01017	1.652e-133	437.0	COG0585@1|root,arCOG04252@2157|Archaea,41S7C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	tRNA pseudouridine synthase	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
SRR25158390_k127_1332506_10	1459636.NTE_01031	1.153e-16	81.0	COG0071@1|root,arCOG01832@2157|Archaea,41T74@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158390_k127_1337155_0	1242864.D187_003878	4.907e-16	90.0	COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
SRR25158390_k127_1340253_4	1459636.NTE_00681	4.321e-104	347.0	COG0010@1|root,arCOG01700@2157|Archaea,41T03@651137|Thaumarchaeota	2157|Archaea	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_1340253_0	1459636.NTE_00682	0.0	1198.0	COG0417@1|root,arCOG15272@2157|Archaea,41S91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
SRR25158390_k127_1340253_5	436308.Nmar_0774	1.993e-83	284.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158390_k127_1340253_16	1459636.NTE_02088	3.407e-26	111.0	arCOG11950@1|root,arCOG11950@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	bPH_3
SRR25158390_k127_1340253_3	1459636.NTE_01027	6.356e-150	484.0	COG1078@1|root,arCOG04430@2157|Archaea,41T0P@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158390_k127_1340253_8	1459636.NTE_01026	6.728e-69	241.0	COG0528@1|root,arCOG00858@2157|Archaea,41T1R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158390_k127_1340253_12	1459636.NTE_01025	1.872e-37	143.0	arCOG08775@1|root,arCOG08775@2157|Archaea,41T9K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1340253_15	1459636.NTE_00825	2.596e-27	114.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158390_k127_1340253_2	1459636.NTE_00824	2.585e-160	512.0	COG1759@1|root,arCOG04346@2157|Archaea,41S79@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Domain of unknown function (DUF1297)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
SRR25158390_k127_1340253_9	1459636.NTE_02658	5.969e-58	209.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	hadL	-	3.1.3.18,3.8.1.2,3.8.1.3	ko:K01091,ko:K01560,ko:K01561,ko:K07025	ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130	-	R01334,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158390_k127_1340253_13	1121930.AQXG01000005_gene616	4.171e-36	143.0	COG0622@1|root,COG0622@2|Bacteria,4PJA1@976|Bacteroidetes,1IZVM@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158390_k127_1340253_14	1459636.NTE_02300	9.457e-31	127.0	arCOG08690@1|root,arCOG08690@2157|Archaea,41T98@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1340253_7	1459636.NTE_01567	1.035e-70	250.0	COG0122@1|root,arCOG00464@2157|Archaea,41SHE@651137|Thaumarchaeota	651137|Thaumarchaeota	L	8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158390_k127_1340253_1	1459636.NTE_03316	1.854e-189	599.0	COG1236@1|root,arCOG00541@2157|Archaea,41SAJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B_6,RMMBL
SRR25158390_k127_1340253_11	1459636.NTE_01318	1.41e-39	148.0	arCOG08720@1|root,arCOG08720@2157|Archaea,41STI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2024
SRR25158390_k127_1340253_17	1459636.NTE_02015	5.607e-25	106.0	COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
SRR25158390_k127_1340253_10	1459636.NTE_03209	3.108e-52	190.0	COG1096@1|root,arCOG00676@2157|Archaea,41SQA@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	-
SRR25158390_k127_1341543_1	1042163.BRLA_c027230	2.263e-25	112.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli,26YMI@186822|Paenibacillaceae	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_1341543_0	697281.Mahau_1243	2.301e-188	613.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,42EQF@68295|Thermoanaerobacterales	186801|Clostridia	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158390_k127_1341543_3	436308.Nmar_1147	3.017e-05	46.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158390_k127_1360001_2	118168.MC7420_7123	3.91e-57	203.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria,1H91U@1150|Oscillatoriales	1117|Cyanobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_1360001_0	1048834.TC41_0139	9.553e-66	240.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158390_k127_1360001_3	1459636.NTE_00644	5.301e-46	171.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1360001_1	1403313.AXBR01000023_gene2644	8.661e-61	219.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZD11@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158390_k127_1384808_14	1459636.NTE_00845	3.682e-06	55.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1384808_16	4538.ORGLA02G0174000.1	1.315e-05	51.0	COG2940@1|root,KOG4442@2759|Eukaryota,37JP7@33090|Viridiplantae,3GD45@35493|Streptophyta,3KVIQ@4447|Liliopsida,3IBQD@38820|Poales	35493|Streptophyta	U	Histone-lysine N-methyltransferase ASHH2-like	-	GO:0000003,GO:0001763,GO:0002682,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006325,GO:0006464,GO:0006479,GO:0006629,GO:0006720,GO:0006721,GO:0006807,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009553,GO:0009555,GO:0009653,GO:0009791,GO:0009893,GO:0009908,GO:0009909,GO:0009910,GO:0009987,GO:0010016,GO:0010223,GO:0010346,GO:0010363,GO:0010452,GO:0010468,GO:0010604,GO:0010638,GO:0010941,GO:0016043,GO:0016108,GO:0016116,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0022414,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031325,GO:0031347,GO:0031399,GO:0031401,GO:0032259,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033043,GO:0033044,GO:0034968,GO:0035670,GO:0036211,GO:0040029,GO:0042054,GO:0042800,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045088,GO:0048229,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048443,GO:0048466,GO:0048467,GO:0048481,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048581,GO:0048583,GO:0048608,GO:0048646,GO:0048653,GO:0048731,GO:0048827,GO:0048831,GO:0048856,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051276,GO:0051568,GO:0060255,GO:0061458,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090567,GO:0099402,GO:0140096,GO:1901564,GO:1902275,GO:1905269,GO:1905393,GO:2000026,GO:2000241,GO:2000242,GO:2001252	2.1.1.43	ko:K11423	ko00310,map00310	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	SET,zf-CW
SRR25158390_k127_1384808_7	1229909.NSED_05305	5.126e-50	184.0	arCOG04006@1|root,arCOG04006@2157|Archaea	2157|Archaea	C	HEAT repeats	-	-	1.14.99.29	ko:K06072	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2
SRR25158390_k127_1384808_4	1131266.ARWQ01000008_gene334	2.214e-72	253.0	COG0483@1|root,arCOG01349@2157|Archaea,41SIF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158390_k127_1384808_9	1459636.NTE_01553	5.072e-34	133.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1384808_13	215358.XP_010745444.1	7.405e-07	59.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata,496SD@7742|Vertebrata,49XMF@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
SRR25158390_k127_1384808_10	1459636.NTE_02412	1.752e-14	76.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_1384808_15	368408.Tpen_0769	1.077e-05	50.0	COG0640@1|root,arCOG03859@2157|Archaea	2157|Archaea	K	ligase activity	-	-	-	ko:K00666,ko:K03892	-	-	-	-	ko00000,ko01000,ko01004,ko03000	-	-	-	HTH_20,HTH_5
SRR25158390_k127_1384808_1	1459636.NTE_01908	2.951e-160	512.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158390_k127_1384808_6	1459636.NTE_01717	5.559e-68	236.0	arCOG08639@1|root,arCOG08639@2157|Archaea,41SP8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1384808_3	1459636.NTE_01562	6.69e-75	261.0	COG0457@1|root,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
SRR25158390_k127_1384808_2	1459636.NTE_00439	5.396e-76	258.0	COG2131@1|root,arCOG01487@2157|Archaea,41SHS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158390_k127_1384808_5	1459636.NTE_00433	3.154e-70	243.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1384808_0	1459636.NTE_01048	1.413e-190	605.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_1384808_8	1459636.NTE_01051	1.256e-39	150.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S6N@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18593	ko00720,ko01120,map00720,map01120	-	R10758	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_1409876_7	1229909.NSED_05585	3.805e-30	124.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR25158390_k127_1409876_3	877455.Metbo_2457	2.721e-56	200.0	COG1839@1|root,arCOG04298@2157|Archaea,2XY40@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
SRR25158390_k127_1409876_10	1121324.CLIT_13c01430	7.794e-12	71.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia	186801|Clostridia	EGP	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_1409876_0	644281.MFS40622_1458	3.373e-185	604.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,23Q6T@183939|Methanococci	183939|Methanococci	O	Belongs to the carbamoyltransferase HypF family	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158390_k127_1409876_8	399549.Msed_0931	2.103e-19	91.0	COG0298@1|root,arCOG04427@2157|Archaea	2157|Archaea	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158390_k127_1409876_1	671065.MetMK1DRAFT_00005540	1.301e-143	464.0	COG0409@1|root,arCOG04428@2157|Archaea,2XPKY@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM hydrogenase formation HypD protein	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158390_k127_1409876_5	671065.MetMK1DRAFT_00005530	4.827e-42	164.0	COG0235@1|root,arCOG04226@2157|Archaea,2XQGF@28889|Crenarchaeota	28889|Crenarchaeota	G	Class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158390_k127_1409876_4	399549.Msed_0929	6.359e-46	174.0	COG0235@1|root,arCOG04226@2157|Archaea,2XR76@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158390_k127_1409876_2	399549.Msed_0933	8.03e-122	400.0	COG0309@1|root,arCOG00636@2157|Archaea,2XPSN@28889|Crenarchaeota	28889|Crenarchaeota	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_1409876_9	517417.Cpar_0318	1.058e-18	92.0	COG1941@1|root,COG1941@2|Bacteria,1FDE2@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
SRR25158390_k127_1409876_6	868864.Dester_0745	4.468e-34	137.0	COG3259@1|root,COG3259@2|Bacteria,2G3XP@200783|Aquificae	200783|Aquificae	C	nickel-dependent hydrogenase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
SRR25158390_k127_1411086_0	4006.Lus10019772	3.981e-11	74.0	COG1409@1|root,COG5077@1|root,KOG1378@2759|Eukaryota,KOG1863@2759|Eukaryota,37I2N@33090|Viridiplantae,3GGCX@35493|Streptophyta,4JFNP@91835|fabids	35493|Streptophyta	G	Purple acid phosphatase	-	GO:0003674,GO:0003824,GO:0003993,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C,Pur_ac_phosph_N
SRR25158390_k127_1416761_0	693661.Arcve_0910	9.432e-62	223.0	arCOG02754@1|root,arCOG02754@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_1418138_0	1459636.NTE_01508	4.155e-09	62.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_14314_5	1459636.NTE_00845	5.153e-08	65.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_14314_2	1459636.NTE_00487	6.053e-70	246.0	COG1475@1|root,arCOG11113@2157|Archaea	2157|Archaea	K	TIGRFAM ParB RepB Spo0J family partition protein	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158390_k127_14314_1	1459636.NTE_00462	1.633e-87	297.0	COG0455@1|root,arCOG00589@2157|Archaea	2157|Archaea	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03496,ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
SRR25158390_k127_14314_4	391009.Tmel_0460	3.15e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,2GD9E@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158390_k127_14314_0	1459636.NTE_01052	2.833e-96	333.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_14314_3	1385935.N836_07015	3.317e-39	156.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158390_k127_14314_6	1243664.CAVL020000019_gene3673	1.106e-06	60.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HCSH@91061|Bacilli,1ZCZY@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_1470089_0	1459636.NTE_00560	2.119e-16	82.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1470380_7	436308.Nmar_0008	1.426e-35	143.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_1470380_6	436308.Nmar_0008	6.632e-48	192.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_1470380_9	35754.JNYJ01000020_gene250	1.164e-31	132.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4D9IZ@85008|Micromonosporales	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158390_k127_1470380_8	1453498.LG45_02080	4.263e-32	134.0	COG0596@1|root,COG0596@2|Bacteria,4NU5X@976|Bacteroidetes,1IIIK@117743|Flavobacteriia,2NV8I@237|Flavobacterium	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_1470380_14	1459636.NTE_00738	1.897e-07	53.0	arCOG10856@1|root,arCOG10856@2157|Archaea	1459636.NTE_00738|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1470380_1	1459636.NTE_03552	1.594e-119	392.0	COG0123@1|root,arCOG00324@2157|Archaea	2157|Archaea	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158390_k127_1470380_11	1459636.NTE_01491	1.402e-25	110.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1470380_4	1459636.NTE_02677	3.009e-102	349.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1470380_3	234267.Acid_0846	2.644e-108	357.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	MA20_17035	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_1470380_10	1459636.NTE_00977	2.653e-28	118.0	COG0010@1|root,arCOG01700@2157|Archaea	2157|Archaea	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_1470380_5	1459636.NTE_00977	1.322e-75	258.0	COG0010@1|root,arCOG01700@2157|Archaea	2157|Archaea	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_1470380_0	756272.Plabr_4288	3.652e-130	423.0	COG2130@1|root,COG2130@2|Bacteria,2IY4S@203682|Planctomycetes	203682|Planctomycetes	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRR25158390_k127_1470380_2	1295642.H839_02156	1.276e-113	374.0	COG2141@1|root,COG2141@2|Bacteria,1TT4S@1239|Firmicutes,4HBJB@91061|Bacilli,1WEVF@129337|Geobacillus	91061|Bacilli	C	Luciferase-like monooxygenase	luxA_2	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_1471119_0	118163.Ple7327_0384	1.657e-68	240.0	COG0412@1|root,COG0412@2|Bacteria,1G1CY@1117|Cyanobacteria	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158390_k127_1471119_4	1229909.NSED_05835	2.049e-08	61.0	arCOG08716@1|root,arCOG10358@1|root,arCOG08716@2157|Archaea,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1471119_2	65497.JODV01000008_gene107	1.354e-22	102.0	COG3291@1|root,COG3291@2|Bacteria,2H4MA@201174|Actinobacteria,4EANI@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
SRR25158390_k127_1471119_5	512565.AMIS_25150	3.189e-08	58.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria,4D8K4@85008|Micromonosporales	201174|Actinobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,RicinB_lectin_2,Ricin_B_lectin,ThuA
SRR25158390_k127_1471119_3	247490.KSU1_D0999	1.783e-21	108.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_1483748_32	1459636.NTE_03299	3.901e-32	130.0	arCOG08025@1|root,arCOG08025@2157|Archaea,41STV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158390_k127_1483748_31	1459636.NTE_02738	2.699e-35	136.0	COG1384@1|root,arCOG00485@2157|Archaea	1459636.NTE_02738|-	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1483748_18	1459636.NTE_02764	4.077e-82	276.0	COG0302@1|root,arCOG04542@2157|Archaea,41SGC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158390_k127_1483748_15	1459636.NTE_02763	2.241e-95	317.0	COG0602@1|root,arCOG02173@2157|Archaea,41SGM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Radical_SAM
SRR25158390_k127_1483748_17	1229909.NSED_09825	6.112e-86	291.0	COG0603@1|root,arCOG00039@2157|Archaea,41SGR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Queuosine biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR25158390_k127_1483748_9	1459636.NTE_02737	1.04e-119	394.0	COG0470@1|root,arCOG00469@2157|Archaea,41SFJ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Replication factor C	-	-	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	DNA_pol3_delta2,Rep_fac_C,RuvB_N
SRR25158390_k127_1483748_26	1459636.NTE_02736	2.297e-51	188.0	arCOG00552@1|root,arCOG00552@2157|Archaea,41SRW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	GINS complex protein	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	Sld5
SRR25158390_k127_1483748_0	1459636.NTE_02735	0.0	1061.0	COG1241@1|root,arCOG00439@2157|Archaea,41SA7@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
SRR25158390_k127_1483748_4	1459636.NTE_01247	9.891e-153	488.0	COG0667@1|root,arCOG01617@2157|Archaea,41S90@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_1483748_27	1459636.NTE_01246	5.631e-46	174.0	COG1715@1|root,arCOG09740@2157|Archaea,41T5F@651137|Thaumarchaeota	651137|Thaumarchaeota	V	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158390_k127_1483748_13	1459636.NTE_01245	5.071e-104	344.0	COG3253@1|root,arCOG03031@2157|Archaea,41SGX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158390_k127_1483748_6	1459636.NTE_01244	2.781e-131	422.0	COG0396@1|root,arCOG04236@2157|Archaea,41SE1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158390_k127_1483748_36	1459636.NTE_01241	6.821e-24	107.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_01241|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1483748_41	1459636.NTE_01240	2.94e-08	56.0	arCOG08678@1|root,arCOG08678@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1483748_16	1459636.NTE_01338	1.186e-93	312.0	COG0202@1|root,arCOG04241@2157|Archaea,41SK0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
SRR25158390_k127_1483748_29	1459636.NTE_01337	9.185e-39	148.0	COG1727@1|root,arCOG00780@2157|Archaea,41SRE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18
SRR25158390_k127_1483748_24	1459636.NTE_01336	8.595e-62	216.0	COG0102@1|root,arCOG04242@2157|Archaea,41SP4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158390_k127_1483748_23	1459636.NTE_01335	3.41e-66	229.0	COG0088@1|root,arCOG04243@2157|Archaea,41SKT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS9 family	-	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158390_k127_1483748_14	1459636.NTE_01339	2.978e-96	319.0	COG1500@1|root,arCOG04187@2157|Archaea,41SC7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	-	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
SRR25158390_k127_1483748_12	1459636.NTE_01342	7.534e-108	355.0	COG1097@1|root,arCOG00678@2157|Archaea,41SHV@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	-	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	KH_1
SRR25158390_k127_1483748_8	1459636.NTE_01343	5.012e-125	404.0	COG0689@1|root,arCOG01575@2157|Archaea,41S81@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	-	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
SRR25158390_k127_1483748_11	1459636.NTE_01344	7.805e-112	366.0	COG2123@1|root,arCOG01574@2157|Archaea,41SFZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	-	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
SRR25158390_k127_1483748_33	1459636.NTE_01345	6.713e-30	120.0	COG1997@1|root,arCOG04208@2157|Archaea,41SUE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal L37ae protein family	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
SRR25158390_k127_1483748_28	1459636.NTE_01347	2.971e-39	149.0	COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
SRR25158390_k127_1483748_22	1459636.NTE_01348	2.794e-68	239.0	COG1948@1|root,arCOG04206@2157|Archaea,41SIH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ERCC4 domain	-	-	-	ko:K10848	ko03420,ko03460,map03420,map03460	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	ERCC4,HHH_5
SRR25158390_k127_1483748_21	1459636.NTE_02410	3.015e-69	241.0	COG3467@1|root,arCOG00520@2157|Archaea,41SJ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158390_k127_1483748_3	1459636.NTE_01248	2.499e-155	496.0	COG1522@1|root,arCOG01628@2157|Archaea,41SA2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1483748_20	1459636.NTE_01384	3.376e-70	243.0	COG0250@1|root,arCOG01920@2157|Archaea,41SM6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
SRR25158390_k127_1483748_19	1459636.NTE_01197	1.185e-72	248.0	COG0080@1|root,arCOG04372@2157|Archaea,41SJW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158390_k127_1483748_1	1459636.NTE_01192	3.06e-284	880.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
SRR25158390_k127_1483748_42	591019.Shell_1181	3.529e-05	49.0	COG0550@1|root,arCOG01527@2157|Archaea,2XQ00@28889|Crenarchaeota	28889|Crenarchaeota	L	DNA topoisomerase, type IA, central domain protein	topA	-	5.99.1.2	ko:K03168,ko:K03169	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
SRR25158390_k127_1483748_25	1459636.NTE_02718	7.54e-52	189.0	COG1056@1|root,arCOG00972@2157|Archaea,41T7B@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158390_k127_1483748_5	1459636.NTE_02721	4.68e-141	461.0	COG0252@1|root,arCOG01924@2157|Archaea,41SD7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158390_k127_1483748_2	1459636.NTE_02722	3.347e-245	772.0	COG2511@1|root,arCOG01719@2157|Archaea,41S8Q@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	-	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
SRR25158390_k127_1483748_40	666685.R2APBS1_3352	5.518e-09	64.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X43I@135614|Xanthomonadales	135614|Xanthomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158390_k127_1483748_10	1459636.NTE_02716	5.841e-112	371.0	COG0430@1|root,arCOG04125@2157|Archaea,41T1K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC
SRR25158390_k127_1483748_30	1459636.NTE_01187	1.459e-38	145.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_1483748_7	1459636.NTE_01188	8.185e-129	422.0	COG0520@1|root,arCOG00065@2157|Archaea,41SYH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158390_k127_1483748_35	1459636.NTE_01189	1.344e-24	111.0	arCOG08028@1|root,arCOG08028@2157|Archaea,41SWE@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1483748_39	1459636.NTE_01263	3.247e-10	64.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_1483748_37	1459636.NTE_01258	4.524e-22	103.0	arCOG08663@1|root,arCOG08663@2157|Archaea,41SR2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1512302_1	1459636.NTE_00218	1.642e-20	98.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_00218|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1512302_0	269797.Mbar_A1346	3.174e-31	126.0	COG3293@1|root,arCOG03506@2157|Archaea	2157|Archaea	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
SRR25158390_k127_1512302_2	653733.Selin_1795	6.968e-15	78.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158390_k127_1518820_1	1459636.NTE_00635	9.215e-75	255.0	COG0163@1|root,arCOG01703@2157|Archaea,41SHU@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158390_k127_1518820_0	1459636.NTE_00636	1.213e-89	304.0	COG0524@1|root,arCOG00014@2157|Archaea,41SX4@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158390_k127_1518820_2	1131266.ARWQ01000018_gene777	2.751e-48	182.0	COG0284@1|root,arCOG00081@2157|Archaea,41SMN@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158390_k127_1518820_3	1459636.NTE_00654	3.694e-31	126.0	arCOG08773@1|root,arCOG08773@2157|Archaea,41SNY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1568879_11	1121289.JHVL01000024_gene123	2.465e-56	201.0	COG0717@1|root,COG0717@2|Bacteria,1V1BE@1239|Firmicutes,24A3M@186801|Clostridia,36G9F@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
SRR25158390_k127_1568879_4	1459636.NTE_01058	5.203e-152	492.0	arCOG04732@1|root,arCOG04732@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1568879_1	1459636.NTE_01048	4.202e-174	559.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_1568879_6	1459636.NTE_02137	1.647e-95	317.0	COG1945@1|root,arCOG04490@2157|Archaea,41SPZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
SRR25158390_k127_1568879_12	1056495.Calag_0594	4.309e-26	113.0	COG1656@1|root,arCOG04290@2157|Archaea,2XQD5@28889|Crenarchaeota	28889|Crenarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
SRR25158390_k127_1568879_0	1459636.NTE_01231	0.0	1159.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158390_k127_1568879_7	373903.Hore_22980	5.156e-87	296.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,24G0B@186801|Clostridia	186801|Clostridia	P	-transport system	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_1568879_8	373903.Hore_22990	2.948e-84	288.0	COG1175@1|root,COG1175@2|Bacteria,1V7U8@1239|Firmicutes,25MIU@186801|Clostridia,3WBQM@53433|Halanaerobiales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_1568879_3	1459636.NTE_01495	3.639e-156	504.0	COG1653@1|root,arCOG00151@2157|Archaea	2157|Archaea	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_1568879_5	511051.CSE_09060	1.488e-111	371.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158390_k127_1568879_9	589924.Ferp_1638	1.562e-70	250.0	COG2152@1|root,arCOG04084@2157|Archaea,2XZSX@28890|Euryarchaeota	28890|Euryarchaeota	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158390_k127_1568879_2	1459636.NTE_01500	1.782e-167	535.0	COG0281@1|root,arCOG00853@2157|Archaea	2157|Archaea	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
SRR25158390_k127_1568879_14	1353276.JADR01000001_gene281	4.36e-11	72.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
SRR25158390_k127_1568879_10	269797.Mbar_A3220	2.769e-63	225.0	COG1842@1|root,arCOG04782@2157|Archaea,2XU11@28890|Euryarchaeota,2N9P1@224756|Methanomicrobia	224756|Methanomicrobia	K	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158390_k127_1568879_15	767817.Desgi_2570	1.482e-09	61.0	COG3360@1|root,COG3360@2|Bacteria,1VF2X@1239|Firmicutes,24QS4@186801|Clostridia,262VS@186807|Peptococcaceae	186801|Clostridia	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158390_k127_1568879_13	269797.Mbar_A2839	1.256e-23	109.0	arCOG04740@1|root,arCOG04740@2157|Archaea,2XU9C@28890|Euryarchaeota,2N9U2@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_160488_0	1459636.NTE_03330	1.691e-113	375.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	2157|Archaea	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_160488_1	1459636.NTE_03333	9.445e-25	113.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
SRR25158390_k127_160488_2	1459636.NTE_03449	8.15e-08	54.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_1653366_1	1459636.NTE_01970	3.537e-150	484.0	COG0667@1|root,arCOG01623@2157|Archaea,41SA6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158390_k127_1653366_0	1459636.NTE_02293	3.234e-237	747.0	COG1855@1|root,arCOG04116@2157|Archaea,41SX0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,T2SSE
SRR25158390_k127_1653366_2	1459636.NTE_03210	5.586e-90	304.0	COG0077@1|root,arCOG00255@2157|Archaea,41SA8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158390_k127_1653366_6	1459636.NTE_03211	7.64e-24	107.0	arCOG08827@1|root,arCOG08827@2157|Archaea,41SUW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1653366_3	1459636.NTE_02375	3.597e-74	257.0	COG0084@1|root,arCOG00891@2157|Archaea,41SGP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158390_k127_1653366_4	483219.LILAB_06120	2.343e-47	193.0	COG1409@1|root,COG1409@2|Bacteria,1MX4X@1224|Proteobacteria	1224|Proteobacteria	N	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRR25158390_k127_1653366_5	247490.KSU1_D0999	1.804e-27	130.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_1654047_2	1229909.NSED_05445	3.188e-05	47.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8H@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1654047_0	335543.Sfum_1119	1.709e-271	866.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MQVC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cation transporter/ATPase, N-terminus	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158390_k127_1654047_1	1242864.D187_003878	6.095e-14	84.0	COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
SRR25158390_k127_1657431_3	483219.LILAB_32590	2.391e-12	71.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1MX4X@1224|Proteobacteria,43C05@68525|delta/epsilon subdivisions,2X7AX@28221|Deltaproteobacteria,2YWKH@29|Myxococcales	28221|Deltaproteobacteria	N	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRR25158390_k127_1657431_1	523850.TON_0811	4.189e-33	134.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
SRR25158390_k127_1657431_2	248742.XP_005649230.1	5.361e-17	92.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158390_k127_1657431_0	1459636.NTE_03510	5.505e-97	327.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158390_k127_1683078_0	930945.SiRe_0134	2.311e-116	385.0	COG0604@1|root,arCOG01458@2157|Archaea,2XPW5@28889|Crenarchaeota	28889|Crenarchaeota	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_1683078_1	1267533.KB906736_gene1024	0.0001203	51.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1684919_2	266117.Rxyl_2895	3.199e-34	139.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158390_k127_1684919_1	436308.Nmar_0573	7.537e-59	209.0	COG1528@1|root,arCOG01095@2157|Archaea	2157|Archaea	P	PFAM Ferritin, Dps family protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158390_k127_1684919_0	1459636.NTE_00592	6.966e-63	227.0	COG2514@1|root,arCOG06106@2157|Archaea	2157|Archaea	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158390_k127_1684919_3	1459636.NTE_02859	4.973e-34	132.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_1690540_2	1459636.NTE_01450	5.936e-170	544.0	COG0001@1|root,arCOG00918@2157|Archaea,41S5Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_1690540_19	1459636.NTE_02166	7.014e-27	115.0	arCOG11431@1|root,arCOG11431@2157|Archaea,41T8G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1690540_20	1218108.KB908291_gene974	1.933e-20	101.0	COG1215@1|root,COG1215@2|Bacteria,4NFXI@976|Bacteroidetes,1HXPW@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_1690540_3	1459636.NTE_01739	4.438e-159	507.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	2157|Archaea	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8,Pyr_redox_2
SRR25158390_k127_1690540_25	1144275.COCOR_04558	5.169e-08	63.0	2C7PU@1|root,33JNE@2|Bacteria	2|Bacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
SRR25158390_k127_1690540_22	1459636.NTE_01738	3.782e-14	73.0	COG2260@1|root,arCOG00906@2157|Archaea,41SUI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
SRR25158390_k127_1690540_6	1459636.NTE_01737	1.748e-105	348.0	COG1093@1|root,arCOG04107@2157|Archaea,41SHY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor 2, alpha subunit	-	-	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
SRR25158390_k127_1690540_11	1459636.NTE_01736	2.232e-71	245.0	COG2109@1|root,arCOG04678@2157|Archaea,41SFP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ATP corrinoid adenosyltransferase	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158390_k127_1690540_15	1459636.NTE_01720	2.71e-41	157.0	COG4063@1|root,arCOG03220@2157|Archaea,41T46@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrahydromethanopterin S-methyltransferase, subunit A	-	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
SRR25158390_k127_1690540_5	1459636.NTE_01352	1.055e-116	381.0	COG2897@1|root,arCOG02019@2157|Archaea,41SZQ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158390_k127_1690540_21	1051632.TPY_3526	7.247e-19	95.0	COG0509@1|root,COG0509@2|Bacteria,1V9VC@1239|Firmicutes,24QN1@186801|Clostridia	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158390_k127_1690540_14	1459636.NTE_01560	1.764e-55	199.0	COG1573@1|root,arCOG00905@2157|Archaea,41SJ1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_1690540_16	985053.VMUT_0848	2.974e-41	159.0	COG0328@1|root,arCOG02942@2157|Archaea,2XR72@28889|Crenarchaeota	28889|Crenarchaeota	L	Reverse transcriptase-like	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158390_k127_1690540_17	1459636.NTE_02216	3.88e-40	153.0	arCOG10514@1|root,arCOG10514@2157|Archaea,41STR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1690540_7	1459636.NTE_02215	1.639e-100	338.0	COG0392@1|root,arCOG00899@2157|Archaea,41SFV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158390_k127_1690540_9	1459636.NTE_02213	9.42e-95	316.0	COG1100@1|root,arCOG01225@2157|Archaea,41T0A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR25158390_k127_1690540_10	1459636.NTE_02212	1.12e-93	317.0	COG0083@1|root,arCOG01027@2157|Archaea,41S89@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158390_k127_1690540_4	1459636.NTE_02211	4.871e-132	426.0	COG1250@1|root,arCOG00249@2157|Archaea	2157|Archaea	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.116,4.2.1.17	ko:K01715,ko:K15019	ko00650,ko00720,ko01120,ko01200,map00650,map00720,map01120,map01200	M00375	R03026,R03045	RC00831,RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158390_k127_1690540_0	1459636.NTE_02319	0.0	1087.0	COG1964@1|root,arCOG00933@2157|Archaea,41SAY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158390_k127_1690540_1	1459636.NTE_03208	7.336e-201	630.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158390_k127_1692175_1	1459636.NTE_00236	1.447e-16	85.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1692175_0	1459636.NTE_01573	1.314e-16	82.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_1695307_0	1459636.NTE_01932	9.479e-121	400.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158390_k127_1695307_2	1459636.NTE_00888	2.665e-09	61.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_1695307_1	436308.Nmar_1680	2.872e-23	102.0	COG0697@1|root,arCOG00273@2157|Archaea,41T37@651137|Thaumarchaeota	651137|Thaumarchaeota	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_1711591_3	588596.U9UU45	1.172e-38	145.0	2F5BE@1|root,2T6C1@2759|Eukaryota,3ADQ4@33154|Opisthokonta,3P7WG@4751|Fungi	588596.U9UU45|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1721765_1	1174528.JH992898_gene3151	2.309e-14	81.0	COG0515@1|root,COG0515@2|Bacteria,1GCAZ@1117|Cyanobacteria,1JMUY@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_1721765_0	1459636.NTE_01573	6.193e-15	77.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_1802829_9	1459636.NTE_03208	1.648e-19	89.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158390_k127_1802829_4	1459636.NTE_03051	1.413e-125	405.0	COG0090@1|root,arCOG04067@2157|Archaea,41SCT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158390_k127_1802829_3	1459636.NTE_01293	1.4e-129	420.0	COG0448@1|root,arCOG00912@2157|Archaea,41SEY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158390_k127_1802829_5	1459636.NTE_01292	6.346e-123	411.0	COG0552@1|root,arCOG01227@2157|Archaea,41SCC@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158390_k127_1802829_8	1459636.NTE_01291	1.481e-39	151.0	COG1730@1|root,arCOG01341@2157|Archaea,41SSP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	-	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
SRR25158390_k127_1802829_2	1459636.NTE_01288	3.732e-157	503.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158390_k127_1802829_1	1459636.NTE_01284	0.0	1143.0	COG0495@1|root,arCOG00809@2157|Archaea,41SES@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158390_k127_1802829_0	1459636.NTE_01283	0.0	1215.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158390_k127_1802829_7	1459636.NTE_01281	1.254e-47	173.0	COG0526@1|root,arCOG01972@2157|Archaea,41SSR@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_1802829_11	693661.Arcve_0910	8.911e-06	52.0	arCOG02754@1|root,arCOG02754@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_1802829_6	521011.Mpal_1345	5.854e-65	233.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_1830852_2	484770.UFO1_2112	5.264e-101	336.0	COG1864@1|root,COG1864@2|Bacteria,1UKQ1@1239|Firmicutes	1239|Firmicutes	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
SRR25158390_k127_1830852_4	1173028.ANKO01000106_gene341	1.839e-84	295.0	COG2837@1|root,COG2837@2|Bacteria	2|Bacteria	P	iron assimilation	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
SRR25158390_k127_1830852_10	106370.Francci3_2176	4.095e-09	65.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1830852_0	1459636.NTE_02802	1.278e-147	481.0	COG1944@1|root,arCOG02882@2157|Archaea	2157|Archaea	H	methanogenesis marker protein 1	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
SRR25158390_k127_1830852_7	1459636.NTE_02460	4.194e-48	181.0	COG1926@1|root,arCOG00041@2157|Archaea	2157|Archaea	F	phosphoribosyltransferases	prt	-	-	ko:K04096,ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158390_k127_1830852_9	1042163.BRLA_c013400	6.245e-22	104.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1830852_1	1459636.NTE_02854	9.878e-111	367.0	COG0614@1|root,arCOG04233@2157|Archaea,41SXD@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158390_k127_1830852_8	1459636.NTE_01649	1.599e-43	167.0	COG1280@1|root,arCOG01947@2157|Archaea,41T36@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Lysine exporter protein LysE YggA	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158390_k127_1830852_5	1123376.AUIU01000012_gene1357	9.547e-55	198.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	Macro
SRR25158390_k127_1830852_3	1131266.ARWQ01000014_gene82	2.124e-85	289.0	COG0846@1|root,arCOG04248@2157|Archaea,41SWP@651137|Thaumarchaeota	651137|Thaumarchaeota	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158390_k127_1830852_6	1459636.NTE_02660	1.756e-49	181.0	COG0537@1|root,arCOG00419@2157|Archaea,41SNI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158390_k127_1843097_0	1459636.NTE_03481	3.694e-167	547.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158390_k127_1843097_4	1459636.NTE_00236	2.689e-17	87.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1843097_1	391587.KAOT1_19772	8.502e-79	275.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_1843097_2	1459636.NTE_00032	2.517e-76	267.0	COG0803@1|root,arCOG01005@2157|Archaea,41T29@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158390_k127_1843097_3	1463885.KL578392_gene2362	1.048e-46	182.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158390_k127_1843097_5	82996.sch_15700	6.732e-16	80.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,4043F@613|Serratia	1236|Gammaproteobacteria	S	ChaB	chaB	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
SRR25158390_k127_184633_0	1459636.NTE_00079	0.0	1468.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
SRR25158390_k127_184633_1	1459636.NTE_00080	4.117e-110	361.0	COG1646@1|root,arCOG01085@2157|Archaea,41SH4@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
SRR25158390_k127_184633_2	1459636.NTE_00081	0.0002801	46.0	arCOG08806@1|root,arCOG08806@2157|Archaea,41SUU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1851214_4	247490.KSU1_D0999	9.8e-19	100.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_1851214_6	436308.Nmar_0204	5.287e-09	59.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1851214_7	1459636.NTE_03327	3.832e-05	54.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1851214_1	373994.Riv7116_0738	5.419e-46	169.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_1851214_5	1459636.NTE_02435	1.62e-13	73.0	arCOG03008@1|root,arCOG03008@2157|Archaea,41STF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_1858392_0	1408422.JHYF01000001_gene2875	1.176e-06	60.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,36FRJ@31979|Clostridiaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158390_k127_1858392_1	694429.Pyrfu_0687	2.435e-05	51.0	COG0144@1|root,arCOG00975@2157|Archaea,2XQIC@28889|Crenarchaeota	28889|Crenarchaeota	J	Fmu (Sun) domain protein	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
SRR25158390_k127_1938842_14	1459636.NTE_01987	2.752e-14	74.0	arCOG05491@1|root,arCOG05491@2157|Archaea,41SVB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1938842_3	1459636.NTE_01229	5.2e-162	514.0	COG0214@1|root,arCOG04075@2157|Archaea,41SEJ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158390_k127_1938842_6	1459636.NTE_01228	9.494e-75	256.0	COG0311@1|root,arCOG00034@2157|Archaea,41SIZ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158390_k127_1938842_11	1459636.NTE_01532	3.014e-22	98.0	arCOG08750@1|root,arCOG08750@2157|Archaea	1459636.NTE_01532|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1938842_5	1459636.NTE_00799	4.291e-96	321.0	COG2107@1|root,arCOG00654@2157|Archaea,41SB8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158390_k127_1938842_1	1459636.NTE_00789	7.028e-176	557.0	COG1060@1|root,arCOG00656@2157|Archaea,41SEG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158390_k127_1938842_2	1459636.NTE_00788	6.524e-168	534.0	COG1060@1|root,arCOG00656@2157|Archaea,41SCN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_1938842_0	1459636.NTE_01316	3.834e-242	754.0	COG3425@1|root,arCOG01767@2157|Archaea,41SAQ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
SRR25158390_k127_1938842_8	1459636.NTE_02715	1.29e-39	153.0	COG5615@1|root,arCOG05392@2157|Archaea,41T4B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
SRR25158390_k127_1938842_9	1459636.NTE_02714	3.609e-27	117.0	arCOG03788@1|root,arCOG03788@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR25158390_k127_1938842_10	1131266.ARWQ01000005_gene797	9.577e-23	103.0	COG1522@1|root,arCOG04153@2157|Archaea,41SP6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1938842_7	521011.Mpal_1345	1.07e-67	242.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_1938842_15	913865.DOT_2970	3.928e-13	74.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158390_k127_1938842_13	1459636.NTE_02333	2.087e-16	84.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1938842_4	1459636.NTE_01534	1.754e-111	372.0	COG0389@1|root,COG1801@1|root,arCOG04291@2157|Archaea,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota	2157|Archaea	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158390_k127_1938842_12	436308.Nmar_1354	7.981e-18	87.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_1938842_18	1123277.KB893182_gene4806	2.801e-09	62.0	COG0745@1|root,COG0745@2|Bacteria,4NHXA@976|Bacteroidetes,47XIC@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_1968149_0	1459636.NTE_01395	1.769e-153	495.0	COG2132@1|root,arCOG03914@2157|Archaea,41S77@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_1970727_9	747365.Thena_0575	3.306e-14	78.0	COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,24QQ6@186801|Clostridia,42H8S@68295|Thermoanaerobacterales	186801|Clostridia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1970727_0	1459636.NTE_01678	7.825e-148	481.0	COG0126@1|root,arCOG00496@2157|Archaea,41SMB@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158390_k127_1970727_3	1229909.NSED_02125	1.266e-65	234.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1970727_5	1459636.NTE_00888	8.382e-31	128.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_1970727_12	1444309.JAQG01000033_gene2952	0.0002844	47.0	COG1695@1|root,COG1695@2|Bacteria,1VC7V@1239|Firmicutes,4HKED@91061|Bacilli,26YDU@186822|Paenibacillaceae	91061|Bacilli	K	transcriptional	padR5	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158390_k127_1970727_2	1459636.NTE_00905	4.028e-86	292.0	COG1814@1|root,arCOG01096@2157|Archaea,41T0M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158390_k127_1970727_11	436308.Nmar_1769	6.785e-05	48.0	COG0531@1|root,arCOG00009@2157|Archaea,41SXX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158390_k127_1970727_1	580327.Tthe_2021	4.356e-123	403.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158390_k127_1970727_6	1197130.BAFM01000013_gene2227	1.107e-30	127.0	arCOG08948@1|root,arCOG11838@1|root,arCOG08948@2157|Archaea,arCOG11838@2157|Archaea,2Y03W@28890|Euryarchaeota	28890|Euryarchaeota	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Ferritin_2
SRR25158390_k127_1970727_4	1459636.NTE_00897	1.654e-63	224.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1970727_10	1128398.Curi_c00810	7.936e-08	64.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,2686Q@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_1970727_8	1123296.JQKE01000130_gene1250	1.201e-18	94.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KQRJ@206351|Neisseriales	206351|Neisseriales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158390_k127_1978982_0	1459636.NTE_02677	1.333e-32	132.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1978982_2	449447.MAE_59770	0.0002575	49.0	COG2044@1|root,COG2044@2|Bacteria,1GQSP@1117|Cyanobacteria	1117|Cyanobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158390_k127_1978982_1	1459636.NTE_00236	1.246e-16	85.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1981469_1	1229909.NSED_03525	6.697e-28	115.0	COG1055@1|root,arCOG00238@2157|Archaea,41SZM@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SRR25158390_k127_1981469_2	523845.AQXV01000025_gene1501	1.388e-13	76.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23QW3@183939|Methanococci	183939|Methanococci	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_1981469_0	368407.Memar_1316	2.514e-90	310.0	COG0733@1|root,arCOG04466@2157|Archaea,2XTG1@28890|Euryarchaeota,2NASA@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SRR25158390_k127_1983846_0	436308.Nmar_0408	1.467e-35	142.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158390_k127_1983846_2	1267533.KB906736_gene1024	1.408e-11	70.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_1983846_1	1459636.NTE_03491	5.7e-14	74.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_1983846_3	491952.Mar181_0965	0.000207	52.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1XH7N@135619|Oceanospirillales	135619|Oceanospirillales	S	Transcription factor	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
SRR25158390_k127_1997606_0	1459636.NTE_01491	0.0001373	49.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2013196_1	693661.Arcve_0574	4.507e-15	82.0	COG3316@1|root,arCOG02134@2157|Archaea,2XUAY@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240,HTH_23
SRR25158390_k127_2013196_0	1459636.NTE_01024	2.476e-22	106.0	arCOG03788@1|root,arCOG03788@2157|Archaea,41T96@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018021_6	1459636.NTE_01473	3.143e-19	93.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158390_k127_2018021_5	1459636.NTE_02528	3.375e-34	141.0	arCOG01247@1|root,arCOG01247@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Phage_integr_3,Phage_integrase
SRR25158390_k127_2018021_2	1459636.NTE_02875	1.05e-46	176.0	COG0637@1|root,arCOG02293@2157|Archaea	2157|Archaea	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,5.4.2.6	ko:K01091,ko:K01838,ko:K07025	ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130	-	R01334,R02728,R11310	RC00017,RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158390_k127_2018021_0	1459636.NTE_02959	1.98e-60	215.0	COG2095@1|root,arCOG01997@2157|Archaea	2157|Archaea	U	UPF0056 membrane protein	snatA	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158390_k127_2018021_4	1459636.NTE_00900	2.091e-36	142.0	COG0517@1|root,arCOG00606@2157|Archaea,41T8N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_2018021_3	436308.Nmar_0506	9.163e-42	161.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41T0Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2018021_1	1459636.NTE_00846	1.633e-59	214.0	COG1994@1|root,COG3582@1|root,arCOG00614@2157|Archaea,arCOG01769@2157|Archaea,41SUB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-AN1
SRR25158390_k127_2018021_7	315730.BcerKBAB4_1380	2.609e-05	49.0	COG5295@1|root,COG5295@2|Bacteria,1VRA2@1239|Firmicutes,4ISF7@91061|Bacilli,1ZS54@1386|Bacillus	91061|Bacilli	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158390_k127_2019364_0	1459636.NTE_03297	1.937e-167	536.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158390_k127_2019364_2	1459636.NTE_01513	4.431e-13	70.0	arCOG10403@1|root,arCOG10403@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2019364_1	931276.Cspa_c31080	2.525e-39	152.0	COG0457@1|root,COG0457@2|Bacteria,1UYZH@1239|Firmicutes,24BU9@186801|Clostridia,36F2E@31979|Clostridiaceae	186801|Clostridia	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRR25158390_k127_2021334_6	1163730.FFONT_0352	0.0009923	43.0	COG0071@1|root,arCOG01833@2157|Archaea,2XQD6@28889|Crenarchaeota	28889|Crenarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_2021334_5	192952.MM_2642	1.445e-13	79.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUHN@28890|Euryarchaeota,2N9I0@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158390_k127_2021334_4	933262.AXAM01000164_gene2940	1.469e-23	114.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria,2MKYI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158390_k127_2021334_0	1459636.NTE_02247	4.76e-167	530.0	COG0535@1|root,arCOG00938@2157|Archaea,41SXS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158390_k127_2021334_2	1459636.NTE_00035	8.505e-49	181.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2021334_1	1459636.NTE_00935	7.06e-82	278.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_2047585_0	1459636.NTE_02683	1.232e-83	284.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158390_k127_2047585_1	1459636.NTE_02682	4.849e-41	160.0	arCOG08818@1|root,arCOG08818@2157|Archaea,41SVV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2137820_3	861360.AARI_13980	0.0008324	47.0	COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2HESC@201174|Actinobacteria,1W8TS@1268|Micrococcaceae	201174|Actinobacteria	D	Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Fibrinogen_C
SRR25158390_k127_2137820_0	1459636.NTE_01028	3.227e-61	216.0	COG0125@1|root,arCOG01891@2157|Archaea,41T33@651137|Thaumarchaeota	651137|Thaumarchaeota	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158390_k127_2137820_1	1459636.NTE_02866	2.918e-38	147.0	arCOG08678@1|root,arCOG08678@2157|Archaea,41SR1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2151694_0	1459636.NTE_00325	1.641e-22	101.0	COG2149@1|root,arCOG05380@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158390_k127_2151694_1	1123239.KB898623_gene1340	5.044e-05	55.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli	91061|Bacilli	S	acetoin utilization protein	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158390_k127_2168534_1	1459636.NTE_01493	2.054e-52	199.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_2168534_4	696281.Desru_2674	1.108e-12	78.0	COG0457@1|root,COG0726@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,261SN@186807|Peptococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158390_k127_2168534_2	436308.Nmar_1271	1.846e-34	143.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_2168534_5	1459636.NTE_01962	1.005e-11	70.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2168534_7	1459636.NTE_01187	6.455e-11	65.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_2168534_0	886293.Sinac_1873	2.382e-109	358.0	COG1028@1|root,COG1028@2|Bacteria,2IZED@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158390_k127_2168534_8	1281779.H009_17983	1.373e-06	57.0	COG0454@1|root,COG0456@2|Bacteria,1N009@1224|Proteobacteria,2U6PP@28211|Alphaproteobacteria,4BECS@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158390_k127_2168534_9	1459636.NTE_02332	3.421e-05	55.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2177577_1	1459636.NTE_00560	5.488e-19	89.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2177577_0	1459636.NTE_01667	1.06e-37	146.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2178696_0	1459636.NTE_01425	1.071e-261	819.0	COG0028@1|root,arCOG01999@2157|Archaea	2157|Archaea	C	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	Rubredoxin,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158390_k127_2178696_1	1459636.NTE_03452	3.637e-11	63.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_2182413_0	1459636.NTE_02637	6.284e-66	234.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158390_k127_218686_1	1459636.NTE_02554	2.599e-06	50.0	COG1143@1|root,arCOG01543@2157|Archaea,41SGW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4
SRR25158390_k127_218686_0	1459636.NTE_01491	1.086e-20	95.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2238100_10	153948.NAL212_0591	7.864e-17	89.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria,2VXM9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2238100_11	913865.DOT_2970	1.21e-13	76.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158390_k127_2238100_2	221288.JH992901_gene3607	1.416e-142	459.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1JIY9@1189|Stigonemataceae	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_2238100_8	1121875.KB907549_gene1810	2.629e-21	104.0	COG0382@1|root,COG0382@2|Bacteria,4NIXM@976|Bacteroidetes,1HZ5B@117743|Flavobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158390_k127_2238100_3	237368.SCABRO_00224	8.313e-136	445.0	COG1524@1|root,COG1524@2|Bacteria,2IXT6@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158390_k127_2238100_7	1122915.AUGY01000020_gene6450	2.739e-23	109.0	COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,4HC31@91061|Bacilli,26Z0E@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158390_k127_2238100_6	1459636.NTE_00729	8.891e-64	230.0	COG5012@1|root,arCOG03932@1|root,arCOG03402@2157|Archaea,arCOG03932@2157|Archaea,41SKB@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2238100_1	1459636.NTE_00731	4.235e-190	600.0	COG0137@1|root,arCOG00112@2157|Archaea,41S6K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158390_k127_2238100_9	1459636.NTE_00732	7.758e-20	90.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41SVX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158390_k127_2238100_4	1459636.NTE_00733	8.009e-116	379.0	COG0189@1|root,arCOG01589@2157|Archaea,41SCQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
SRR25158390_k127_2238100_0	1459636.NTE_00734	9.735e-200	625.0	COG0002@1|root,arCOG00495@2157|Archaea,41S8R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158390_k127_2238100_5	1459636.NTE_00735	3.519e-94	313.0	COG0548@1|root,arCOG00862@2157|Archaea,41SFB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis)	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158390_k127_2245014_0	1459636.NTE_00059	3.041e-137	447.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158390_k127_2245014_1	1459636.NTE_01492	7.536e-52	191.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_224537_4	1487953.JMKF01000017_gene2547	7.665e-40	151.0	COG0599@1|root,COG0599@2|Bacteria,1G6DQ@1117|Cyanobacteria	1117|Cyanobacteria	S	gamma-carboxymuconolactone decarboxylase subunit	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158390_k127_224537_2	1459636.NTE_01298	1.472e-72	252.0	COG0500@1|root,arCOG01631@2157|Archaea,41SJC@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DOT1
SRR25158390_k127_224537_0	1131266.ARWQ01000028_gene1022	2.55e-226	712.0	COG1866@1|root,arCOG06073@2157|Archaea,41SE5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158390_k127_224537_1	1459636.NTE_00430	8.394e-115	374.0	COG4221@1|root,arCOG01265@2157|Archaea,41S66@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_224537_3	545697.HMPREF0216_03045	4.727e-45	178.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,249J5@186801|Clostridia,36E41@31979|Clostridiaceae	186801|Clostridia	C	NADH dehydrogenase, FAD-containing subunit	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DoxD,DoxX,Pyr_redox_2
SRR25158390_k127_224537_5	1459636.NTE_02412	5.129e-16	80.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_227280_2	596152.DesU5LDRAFT_2681	7.366e-25	105.0	2DN97@1|root,32W7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_227280_0	1459636.NTE_01450	8.562e-173	552.0	COG0001@1|root,arCOG00918@2157|Archaea,41S5Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_227280_1	1459636.NTE_02166	7.014e-27	115.0	arCOG11431@1|root,arCOG11431@2157|Archaea,41T8G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_23	1459636.NTE_02772	8.17e-08	54.0	COG4799@1|root,arCOG02705@2157|Archaea,41SEH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18604	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
SRR25158390_k127_2284913_21	1459636.NTE_02769	1.126e-17	84.0	arCOG08785@1|root,arCOG08785@2157|Archaea,41SVD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
SRR25158390_k127_2284913_20	1459636.NTE_02768	6.309e-18	88.0	arCOG08784@1|root,arCOG08784@2157|Archaea,41SVZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_7	1459636.NTE_02767	1.849e-105	355.0	COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA
SRR25158390_k127_2284913_5	1459636.NTE_02766	2.575e-156	501.0	arCOG08783@1|root,arCOG08783@2157|Archaea,41SFX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_8	1459636.NTE_02745	3.039e-102	335.0	COG0049@1|root,arCOG04254@2157|Archaea,41S6U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158390_k127_2284913_10	1459636.NTE_02746	5.669e-80	267.0	COG0048@1|root,arCOG04255@2157|Archaea,41SIB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158390_k127_2284913_11	1459636.NTE_02747	3.566e-67	231.0	COG0195@1|root,arCOG01760@2157|Archaea,41SJQ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
SRR25158390_k127_2284913_0	1459636.NTE_02749	0.0	2145.0	COG0086@1|root,arCOG04256@2157|Archaea,arCOG04257@2157|Archaea,41SB2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158390_k127_2284913_1	1459636.NTE_02750	0.0	2023.0	COG0085@1|root,arCOG01762@2157|Archaea,41SF5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158390_k127_2284913_15	1459636.NTE_02751	2.646e-37	141.0	COG2012@1|root,arCOG04258@2157|Archaea,41SU8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	-	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
SRR25158390_k127_2284913_9	1459636.NTE_02754	1.155e-89	304.0	COG0327@1|root,arCOG04454@2157|Archaea	2157|Archaea	S	NGG1p interacting factor 3	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_4	1459636.NTE_02755	3.319e-167	531.0	COG0731@1|root,arCOG04174@2157|Archaea,41SBS@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
SRR25158390_k127_2284913_12	1459636.NTE_02330	1.648e-60	214.0	arCOG10136@1|root,arCOG10136@2157|Archaea,41T5E@651137|Thaumarchaeota	651137|Thaumarchaeota	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
SRR25158390_k127_2284913_19	1459636.NTE_02329	3.621e-23	103.0	arCOG08657@1|root,arCOG08657@2157|Archaea,41SRB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_2	1459636.NTE_02328	9.533e-176	561.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	2157|Archaea	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158390_k127_2284913_3	1459636.NTE_02760	4.977e-170	542.0	COG0012@1|root,arCOG00357@2157|Archaea,41S71@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
SRR25158390_k127_2284913_6	1459636.NTE_02759	6.883e-139	449.0	COG0533@1|root,arCOG01183@2157|Archaea,41SDX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37	kae1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158390_k127_2284913_16	1459636.NTE_02758	2.059e-30	123.0	arCOG10590@1|root,arCOG10590@2157|Archaea,41SSG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_13	1459636.NTE_02757	3.946e-60	214.0	COG0533@1|root,arCOG01185@2157|Archaea,41SJJ@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Mn2 -dependent serine threonine protein kinase	-	-	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	Pkinase
SRR25158390_k127_2284913_14	1459636.NTE_02756	1.501e-52	192.0	COG0127@1|root,arCOG04184@2157|Archaea,41SKW@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the HAM1 NTPase family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158390_k127_2284913_24	195522.BD01_1371	2.943e-06	53.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_2284913_18	1459636.NTE_02704	3.106e-24	103.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2284913_25	1459636.NTE_02918	0.0003352	48.0	arCOG08706@1|root,arCOG08706@2157|Archaea,41SUP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2286129_1	1459636.NTE_02810	4.335e-122	399.0	COG0330@1|root,arCOG01915@2157|Archaea	2157|Archaea	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158390_k127_2286129_10	1459636.NTE_01458	3.684e-28	117.0	arCOG10549@1|root,arCOG10549@2157|Archaea	1459636.NTE_01458|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2286129_3	1459636.NTE_01052	6.739e-91	332.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_2286129_2	1131266.ARWQ01000008_gene303	3.043e-93	313.0	COG0726@1|root,arCOG02877@2157|Archaea	2157|Archaea	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158390_k127_2286129_5	1042326.AZNV01000048_gene1247	2.237e-60	216.0	COG0110@1|root,COG0110@2|Bacteria,1RAKB@1224|Proteobacteria,2U3JX@28211|Alphaproteobacteria,4BA2Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158390_k127_2286129_0	1459636.NTE_00523	5.465e-133	434.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	2157|Archaea	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665,ko:K06883	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158390_k127_2286129_4	1459636.NTE_03049	9.25e-65	227.0	COG0122@1|root,arCOG00464@2157|Archaea	2157|Archaea	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158390_k127_2286129_11	1121121.KB894308_gene201	1.471e-27	123.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2286129_6	1459636.NTE_01508	2.901e-43	165.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2286129_7	1459636.NTE_02871	5.8e-38	145.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
SRR25158390_k127_2286581_2	1459636.NTE_03308	1.667e-59	213.0	COG1515@1|root,arCOG00929@2157|Archaea	2157|Archaea	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158390_k127_2286581_1	868131.MSWAN_1817	1.019e-60	212.0	COG5485@1|root,arCOG06513@2157|Archaea,2Y3E5@28890|Euryarchaeota	28890|Euryarchaeota	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158390_k127_2286581_6	1894.JOER01000042_gene6512	1.521e-05	52.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158390_k127_2286581_4	656024.FsymDg_0437	3.764e-45	167.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_2286581_3	1459636.NTE_00136	3.916e-56	207.0	COG1938@1|root,arCOG00347@2157|Archaea,41SSA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158390_k127_2286581_0	436308.Nmar_1695	2.479e-118	389.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158390_k127_2290434_1	1131266.ARWQ01000008_gene329	5.324e-09	64.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2291264_3	1459636.NTE_03481	1.493e-12	70.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
SRR25158390_k127_2291264_0	1459636.NTE_00795	5.659e-152	494.0	COG1055@1|root,arCOG00238@2157|Archaea,41SXH@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158390_k127_2291264_1	1459636.NTE_03455	2.134e-135	442.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158390_k127_2291264_4	1459636.NTE_03456	1.578e-11	70.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_03456|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2291264_2	1459636.NTE_02435	3.362e-17	84.0	arCOG03008@1|root,arCOG03008@2157|Archaea,41STF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_2303582_12	870187.Thini_0408	6.332e-08	62.0	COG3209@1|root,COG3325@1|root,COG4222@1|root,COG3209@2|Bacteria,COG3325@2|Bacteria,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	DUF4849,Phytase-like
SRR25158390_k127_2303582_2	1459636.NTE_02173	1.122e-168	537.0	COG0505@1|root,arCOG00064@2157|Archaea,41SF0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158390_k127_2303582_13	436308.Nmar_1085	0.0008002	42.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158390_k127_2303582_0	1459636.NTE_02172	0.0	1466.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158390_k127_2303582_8	1459636.NTE_02171	5.266e-60	216.0	COG1407@1|root,arCOG01150@2157|Archaea,41SJB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158390_k127_2303582_6	1459636.NTE_02167	3.676e-100	333.0	COG2759@1|root,arCOG04538@2157|Archaea,41S6B@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158390_k127_2303582_10	999411.HMPREF1092_02322	1.463e-32	133.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,36JPF@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158390_k127_2303582_4	1459636.NTE_02169	4.799e-145	471.0	COG0151@1|root,arCOG04415@2157|Archaea,41SB3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158390_k127_2303582_11	1229909.NSED_06305	1.287e-18	89.0	COG5431@1|root,arCOG01120@2157|Archaea,41SW3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2303582_7	1459636.NTE_02921	2.49e-76	261.0	COG0299@1|root,arCOG02825@2157|Archaea,41SH3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosylglycinamide formyltransferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158390_k127_2303582_5	1459636.NTE_02920	6.772e-107	357.0	COG1236@1|root,arCOG00545@2157|Archaea,41SYB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_2303582_1	1459636.NTE_02919	2.247e-212	662.0	COG2141@1|root,arCOG02410@2157|Archaea,41SBM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_2303582_9	1459636.NTE_02186	6.302e-57	200.0	COG2522@1|root,arCOG00017@2157|Archaea,41SJZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transcriptional regulator	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_2303582_3	1459636.NTE_02050	6.046e-148	477.0	COG3635@1|root,arCOG01696@2157|Archaea,41S6M@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158390_k127_2307073_2	283942.IL0760	2.205e-09	69.0	COG1555@1|root,COG1555@2|Bacteria,1RFDG@1224|Proteobacteria	1224|Proteobacteria	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2307073_0	227086.JGI_V11_82342	1.383e-14	85.0	COG1409@1|root,KOG1378@2759|Eukaryota	2759|Eukaryota	E	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C,Pur_ac_phosph_N
SRR25158390_k127_2323818_8	1459636.NTE_02998	3.767e-64	228.0	COG0685@1|root,arCOG00475@2157|Archaea,41SNK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	cytochrome-c peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2323818_6	1459636.NTE_02997	9.444e-113	369.0	COG1116@1|root,arCOG00193@2157|Archaea,41S6Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158390_k127_2323818_5	1459636.NTE_00628	4.365e-115	383.0	COG1867@1|root,arCOG01219@2157|Archaea,41SAG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	-	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
SRR25158390_k127_2323818_10	1459636.NTE_00626	3.804e-56	203.0	COG0164@1|root,arCOG04121@2157|Archaea,41SK9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158390_k127_2323818_7	1459636.NTE_00625	1.682e-99	330.0	COG0513@1|root,arCOG00078@2157|Archaea,41SM2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
SRR25158390_k127_2323818_3	1459636.NTE_00624	5.586e-127	419.0	COG1498@1|root,arCOG01923@2157|Archaea,41SY9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	NOSIC (NUC001) domain	-	-	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
SRR25158390_k127_2323818_12	1459636.NTE_01618	1.171e-47	175.0	COG1310@1|root,arCOG01139@2157|Archaea,41SQ7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158390_k127_2323818_14	1459636.NTE_01615	2.065e-37	143.0	arCOG08751@1|root,arCOG08751@2157|Archaea,41SS7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2323818_17	868131.MSWAN_1251	2.527e-26	120.0	COG0457@1|root,arCOG00127@1|root,arCOG05195@1|root,arCOG00127@2157|Archaea,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG05195@2157|Archaea,2XUNW@28890|Euryarchaeota,23PX5@183925|Methanobacteria	28890|Euryarchaeota	S	Tetratricopeptide TPR-1	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158390_k127_2323818_1	1459636.NTE_00771	9.921e-168	542.0	COG1173@1|root,arCOG00749@2157|Archaea,41SFE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_2323818_2	1459636.NTE_00772	2.501e-146	470.0	COG0601@1|root,arCOG00751@2157|Archaea,41S7B@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158390_k127_2323818_16	1459636.NTE_02314	5.342e-28	116.0	COG1324@1|root,arCOG04231@2157|Archaea,41SR4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158390_k127_2323818_13	1280686.AUKE01000018_gene2848	1.365e-42	165.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,4BX1F@830|Butyrivibrio	186801|Clostridia	T	Protein phosphatase 2C	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158390_k127_2323818_4	1459636.NTE_02315	1.017e-120	397.0	COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
SRR25158390_k127_2323818_11	436308.Nmar_0110	3.829e-49	181.0	arCOG08723@1|root,arCOG08723@2157|Archaea,41SPX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2323818_15	1459636.NTE_02002	3.547e-35	137.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2323818_0	1459636.NTE_02324	5.489e-180	575.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
SRR25158390_k127_2323818_9	1459636.NTE_02217	1.654e-63	224.0	COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota	2157|Archaea	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
SRR25158390_k127_2324131_2	1459636.NTE_00844	2.37e-15	78.0	COG1335@1|root,arCOG01943@2157|Archaea	2157|Archaea	Q	COG1335 Amidases related to nicotinamidase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158390_k127_2324131_4	335659.S23_64250	0.0007936	44.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,3JQU4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NHL repeat	MA20_20600	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158390_k127_2324131_1	269797.Mbar_A0416	6.799e-58	212.0	arCOG03561@1|root,arCOG03561@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_2324131_3	1121870.AUAA01000007_gene150	2.797e-07	63.0	COG0516@1|root,COG0516@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia,3HGNU@358033|Chryseobacterium	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_2324131_0	1459636.NTE_03484	9.681e-181	574.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_2329828_0	1459636.NTE_01648	7.301e-190	598.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_2329828_1	693661.Arcve_1601	3.344e-13	72.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_2329828_3	693661.Arcve_1601	2.705e-05	49.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_2329828_2	1459636.NTE_01770	2.462e-11	67.0	COG0582@1|root,arCOG01245@2157|Archaea,41SVT@651137|Thaumarchaeota	1459636.NTE_01770|-	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2338548_3	436308.Nmar_0978	2.68e-17	85.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158390_k127_2338548_0	436308.Nmar_0977	5.749e-127	420.0	COG0702@1|root,arCOG03015@2157|Archaea	2157|Archaea	GM	NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_10
SRR25158390_k127_2338548_2	1459636.NTE_02427	1.179e-20	99.0	arCOG06357@1|root,arCOG06357@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2338548_1	1232437.KL661977_gene3753	1.23e-107	365.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2MI2V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SRR25158390_k127_24354_4	1459636.NTE_00658	4.618e-07	53.0	arCOG10584@1|root,arCOG10584@2157|Archaea,41SV6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial Fe(2+) trafficking	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR25158390_k127_24354_1	1459636.NTE_02865	9.35e-13	71.0	arCOG10406@1|root,arCOG10406@2157|Archaea,41SVU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger, C2H2 type	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2
SRR25158390_k127_24354_0	1459636.NTE_00770	2.853e-57	202.0	COG0231@1|root,arCOG04277@2157|Archaea,41SNP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	-	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	eIF-5a
SRR25158390_k127_24354_2	1107311.Q767_11610	5.811e-09	67.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,1HYRX@117743|Flavobacteriia,2NST0@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_2476384_3	1459636.NTE_02664	1.688e-12	79.0	COG1409@1|root,arCOG06534@1|root,arCOG07781@1|root,arCOG09729@1|root,arCOG06534@2157|Archaea,arCOG07781@2157|Archaea,arCOG09729@2157|Archaea,arCOG11020@2157|Archaea	2157|Archaea	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,CHB_HEX_C_1,He_PIG,PKD,Polysacc_deac_1
SRR25158390_k127_2476384_1	1123366.TH3_17402	1.99e-31	132.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2JSXK@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,FecR,HemolysinCabind,Laminin_G_3
SRR25158390_k127_2476384_4	1459636.NTE_02333	4.04e-12	71.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2476384_2	1079986.JH164837_gene5938	6.174e-24	104.0	COG4274@1|root,COG4274@2|Bacteria,2IN0N@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158390_k127_2496023_3	1459636.NTE_00236	9.136e-19	91.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2496023_2	1459636.NTE_01183	1.734e-26	115.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
SRR25158390_k127_2496023_0	1459636.NTE_01183	9.785e-28	116.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
SRR25158390_k127_2496023_4	1459636.NTE_01183	2.661e-16	83.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
SRR25158390_k127_2496023_1	1459636.NTE_02830	1.576e-26	119.0	COG1073@1|root,arCOG01661@2157|Archaea	2157|Archaea	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158390_k127_2505035_0	1041930.Mtc_0621	1.578e-27	118.0	arCOG02754@1|root,arCOG10890@1|root,arCOG02754@2157|Archaea,arCOG10890@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_2505035_1	693661.Arcve_0910	1.468e-22	102.0	arCOG02754@1|root,arCOG02754@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_2536239_0	1459636.NTE_02677	1.589e-22	99.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2536239_1	395961.Cyan7425_3678	5.922e-15	79.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2542618_0	391587.KAOT1_19772	3.817e-77	268.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_2563077_15	1459636.NTE_02704	1.3e-27	113.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2563077_4	1459636.NTE_01467	4.771e-140	467.0	COG3356@1|root,arCOG04351@2157|Archaea,41S7S@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
SRR25158390_k127_2563077_16	1459636.NTE_01468	6.889e-21	93.0	COG4023@1|root,arCOG02957@2157|Archaea,41SUS@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Sec61beta family	-	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
SRR25158390_k127_2563077_13	1459636.NTE_01470	1.231e-51	184.0	COG0023@1|root,arCOG04223@2157|Archaea,41SNU@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR25158390_k127_2563077_3	1459636.NTE_01473	2.919e-185	580.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158390_k127_2563077_0	1459636.NTE_00773	1.625e-268	848.0	COG3889@1|root,arCOG10597@1|root,arCOG01672@2157|Archaea,arCOG10597@2157|Archaea,41SA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158390_k127_2563077_14	1459636.NTE_00016	3.707e-49	185.0	COG1058@1|root,arCOG00215@2157|Archaea	2157|Archaea	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	cinA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158390_k127_2563077_11	1459636.NTE_02599	8.101e-89	303.0	COG1829@1|root,arCOG04263@2157|Archaea,41T1V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	kinase, sugar kinase superfamily	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
SRR25158390_k127_2563077_12	1459636.NTE_02600	4.044e-82	280.0	COG1701@1|root,arCOG04262@2157|Archaea,41SXP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pfam:DUF137	-	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
SRR25158390_k127_2563077_8	1459636.NTE_02601	2.458e-102	341.0	COG0413@1|root,arCOG00584@2157|Archaea,41SZX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158390_k127_2563077_6	1459636.NTE_02602	1.531e-124	412.0	COG0452@1|root,arCOG01704@2157|Archaea,41SYG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158390_k127_2563077_7	1459636.NTE_02604	8.622e-112	372.0	COG0006@1|root,arCOG01000@2157|Archaea,41T14@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158390_k127_2563077_2	1459636.NTE_02607	2.862e-196	617.0	COG0075@1|root,arCOG00082@2157|Archaea,41SZZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158390_k127_2563077_10	1459636.NTE_02621	2.556e-92	311.0	COG1047@1|root,arCOG00980@2157|Archaea,41T0T@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158390_k127_2563077_5	1459636.NTE_01413	7.077e-131	426.0	COG0371@1|root,arCOG00982@2157|Archaea,41T0B@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
SRR25158390_k127_2563077_17	1459636.NTE_01414	5.736e-19	89.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158390_k127_2563077_1	1459636.NTE_01415	5.761e-201	644.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	651137|Thaumarchaeota	S	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
SRR25158390_k127_2563077_9	1459636.NTE_01308	3.351e-93	314.0	COG0727@1|root,arCOG02579@2157|Archaea,41SH8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158390_k127_2563077_18	1459636.NTE_01469	1.391e-07	55.0	COG1645@1|root,arCOG00578@2157|Archaea,41SVN@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	-	-	-	ko:K07143	-	-	-	-	ko00000	-	-	-	Auto_anti-p27
SRR25158390_k127_2565191_13	1459636.NTE_03327	1.496e-27	119.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2565191_3	858215.Thexy_1133	4.007e-96	332.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,42F2C@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
SRR25158390_k127_2565191_17	1459636.NTE_03258	2.2e-19	89.0	arCOG10546@1|root,arCOG10546@2157|Archaea,41SRD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2565191_1	1121935.AQXX01000064_gene3308	1.566e-129	424.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,1XPTW@135619|Oceanospirillales	135619|Oceanospirillales	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SRR25158390_k127_2565191_14	1459636.NTE_00144	9.556e-23	104.0	arCOG03593@1|root,arCOG03593@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795,PRC
SRR25158390_k127_2565191_2	1459636.NTE_01099	7.023e-99	329.0	COG1409@1|root,arCOG01153@2157|Archaea,41SF2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158390_k127_2565191_20	1459636.NTE_01035	1.46e-10	62.0	COG0640@1|root,COG1809@1|root,arCOG00394@2157|Archaea,arCOG04896@2157|Archaea	2157|Archaea	K	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158390_k127_2565191_7	1459636.NTE_03244	6.291e-68	243.0	COG1237@1|root,arCOG00503@2157|Archaea	2157|Archaea	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158390_k127_2565191_12	1459636.NTE_00422	2.408e-28	115.0	arCOG08799@1|root,arCOG08799@2157|Archaea,41T6M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2565191_10	1459636.NTE_02416	3.512e-33	137.0	COG0671@1|root,arCOG03056@2157|Archaea	2157|Archaea	I	PFAM phosphoesterase, PA-phosphatase related	sepP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158390_k127_2565191_16	1459636.NTE_00575	4.157e-21	95.0	arCOG04557@1|root,arCOG04557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2565191_0	1459636.NTE_00239	1.949e-130	421.0	COG3546@1|root,arCOG07055@2157|Archaea	2157|Archaea	P	COG3546 Mn-containing catalase	-	-	-	ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
SRR25158390_k127_2565191_6	1459636.NTE_02508	5.455e-75	259.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
SRR25158390_k127_2565191_15	436308.Nmar_0879	1.53e-21	96.0	arCOG08746@1|root,arCOG08746@2157|Archaea,41SWA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
SRR25158390_k127_2565191_8	1459636.NTE_02510	1.253e-47	178.0	arCOG02103@1|root,arCOG02103@2157|Archaea,41T51@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF4443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4443
SRR25158390_k127_2565191_4	1459636.NTE_01334	3.712e-93	313.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_2565191_5	1131266.ARWQ01000004_gene1476	4.488e-82	282.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2565191_22	436308.Nmar_0978	6.704e-06	49.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158390_k127_2588876_3	1459636.NTE_03205	1.063e-17	86.0	arCOG10515@1|root,arCOG10515@2157|Archaea,41TAP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2588876_2	999630.TUZN_0749	4.076e-23	102.0	COG1254@1|root,arCOG01674@2157|Archaea,2XR8S@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158390_k127_2588876_0	1459636.NTE_03207	1.278e-199	630.0	COG0019@1|root,arCOG02268@2157|Archaea	2157|Archaea	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.17,4.1.1.20,4.1.1.96	ko:K01581,ko:K01586,ko:K13747	ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230	M00016,M00134,M00525,M00526,M00527	R00451,R00670,R09081,R09082	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2177	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158390_k127_2588876_1	1459636.NTE_03208	4.938e-92	305.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158390_k127_2590474_4	570268.ANBB01000015_gene3701	6.231e-05	55.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4EG2J@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_2590474_2	1459636.NTE_02412	9.297e-15	77.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_2590474_0	1459636.NTE_02830	7.103e-67	244.0	COG1073@1|root,arCOG01661@2157|Archaea	2157|Archaea	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158390_k127_2590474_3	1459636.NTE_03491	1.016e-14	77.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_2595388_2	526222.Desal_2074	1.708e-09	66.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria,2M8AQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,FecR,HCBP_related,He_PIG,HemolysinCabind,Peptidase_M91,VWA,VWA_2
SRR25158390_k127_2595388_0	1459636.NTE_01932	2.017e-98	334.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158390_k127_2595388_1	234267.Acid_3939	5.295e-65	242.0	COG0053@1|root,COG0053@2|Bacteria,3Y43E@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158390_k127_2605671_2	247490.KSU1_D0999	2.12e-26	122.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_2605671_1	1457250.BBMO01000002_gene2461	2.855e-30	132.0	arCOG07550@1|root,arCOG07550@2157|Archaea,2XTFE@28890|Euryarchaeota,23U84@183963|Halobacteria	183963|Halobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF726,DUF900
SRR25158390_k127_2605671_0	1121468.AUBR01000078_gene861	2.651e-37	153.0	COG0433@1|root,COG0433@2|Bacteria,1TRDI@1239|Firmicutes,24CT8@186801|Clostridia,42IS7@68295|Thermoanaerobacterales	186801|Clostridia	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_2616734_17	469383.Cwoe_4056	1.31e-07	54.0	COG3467@1|root,COG3467@2|Bacteria,2I2X2@201174|Actinobacteria,4CU4F@84995|Rubrobacteria	84995|Rubrobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2616734_12	1120973.AQXL01000117_gene343	4.571e-15	80.0	2F6QX@1|root,33Z76@2|Bacteria,1VY7H@1239|Firmicutes,4HWZV@91061|Bacilli,27A4C@186823|Alicyclobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2616734_16	1192034.CAP_7835	1.288e-07	54.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,42V19@68525|delta/epsilon subdivisions,2WSZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_2616734_18	1116472.MGMO_103c00060	0.0003521	45.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1XF24@135618|Methylococcales	135618|Methylococcales	S	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_2616734_15	1122939.ATUD01000004_gene3924	2.187e-09	64.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4CQ34@84995|Rubrobacteria	84995|Rubrobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158390_k127_2616734_10	436308.Nmar_0787	2.673e-32	130.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SS2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_2616734_3	221288.JH992901_gene2423	1.415e-136	441.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2616734_4	436308.Nmar_0654	2.387e-75	257.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158390_k127_2616734_6	1459636.NTE_00763	1.907e-67	238.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea,41SFU@651137|Thaumarchaeota	2157|Archaea	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158390_k127_2616734_5	521011.Mpal_1345	1.556e-72	256.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_2616734_13	1459636.NTE_03227	9.319e-12	66.0	arCOG07262@1|root,arCOG07262@2157|Archaea	2157|Archaea	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_2616734_0	1459636.NTE_01166	1.2e-211	666.0	COG1012@1|root,arCOG01252@2157|Archaea,41T0F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135,ko:K18601	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158390_k127_2616734_2	1459636.NTE_01163	5.245e-173	548.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_2616734_7	997296.PB1_10899	1.624e-58	223.0	COG0584@1|root,COG3540@1|root,COG0584@2|Bacteria,COG3540@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,1ZPVG@1386|Bacillus	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,PhoD,PhoD_N
SRR25158390_k127_2616734_1	1459636.NTE_01165	1.568e-189	597.0	2DZ6E@1|root,2N57Q@2157|Archaea	2157|Archaea	S	Major royal jelly protein	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158390_k127_2616734_8	1459636.NTE_00950	1.253e-41	154.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
SRR25158390_k127_2617093_1	1459636.NTE_03499	2.529e-79	273.0	COG5486@1|root,arCOG10678@2157|Archaea	2157|Archaea	S	metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158390_k127_2617093_0	1459636.NTE_00752	9.61e-104	340.0	COG5588@1|root,arCOG11393@2157|Archaea	1459636.NTE_00752|-	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2617093_8	10029.XP_007611111.1	0.0001619	49.0	KOG3780@1|root,KOG3780@2759|Eukaryota,38D4U@33154|Opisthokonta,3BJG5@33208|Metazoa,3CY2I@33213|Bilateria,47ZDB@7711|Chordata,48YNT@7742|Vertebrata,3J9TZ@40674|Mammalia,35G74@314146|Euarchontoglires,4Q18C@9989|Rodentia	33208|Metazoa	S	Arrestin (or S-antigen), C-terminal domain	ARRDC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0031410,GO:0031982,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097708	-	-	-	-	-	-	-	-	-	-	Arrestin_C,Arrestin_N
SRR25158390_k127_2617093_4	1459636.NTE_01729	2.404e-19	93.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158390_k127_2617093_2	1459636.NTE_01066	9.549e-49	176.0	arCOG10152@1|root,arCOG10152@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158390_k127_2617093_5	1459636.NTE_02515	1.664e-12	72.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_2617093_6	1459636.NTE_00888	1.637e-09	60.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_2617093_3	443144.GM21_2393	2.424e-22	108.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2617093_9	1463825.JNXC01000040_gene5132	0.0002117	51.0	2BGAN@1|root,32A83@2|Bacteria,2GPQS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_53	1459636.NTE_01015	7.711e-25	113.0	arCOG08733@1|root,arCOG08733@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_43	1459636.NTE_01014	4.025e-43	162.0	arCOG10527@1|root,arCOG10527@2157|Archaea,41SPB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_34	1459636.NTE_01380	4.81e-62	219.0	arCOG08734@1|root,arCOG08734@2157|Archaea,41SP9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_66	1229909.NSED_09270	1.219e-10	64.0	arCOG07262@1|root,arCOG07262@2157|Archaea,41T8B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_49	1459636.NTE_01377	6.673e-30	124.0	arCOG08731@1|root,arCOG08731@2157|Archaea,41STT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_15	1459636.NTE_01360	1.775e-127	425.0	COG0640@1|root,arCOG00472@2157|Archaea	2157|Archaea	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_16,AAA_22,DUF2791,HTH_5
SRR25158390_k127_2628366_44	1459636.NTE_01359	1.03e-39	156.0	arCOG03737@1|root,arCOG03737@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_51	1459636.NTE_02641	9.989e-27	113.0	COG0073@1|root,arCOG01136@2157|Archaea,41SSY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRR25158390_k127_2628366_32	1459636.NTE_02643	2.166e-71	251.0	COG2084@1|root,arCOG00247@2157|Archaea,41SI2@651137|Thaumarchaeota	651137|Thaumarchaeota	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158390_k127_2628366_48	1459636.NTE_02651	6.871e-35	135.0	COG2146@1|root,arCOG02852@2157|Archaea,41T71@651137|Thaumarchaeota	651137|Thaumarchaeota	P	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158390_k127_2628366_4	1459636.NTE_02650	8.373e-174	557.0	COG0719@1|root,arCOG01715@2157|Archaea,41S7W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufD	-	-	-	ko:K09014,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158390_k127_2628366_0	1459636.NTE_02649	8.005e-280	863.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158390_k127_2628366_68	35841.BT1A1_2392	3.785e-10	70.0	COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRR25158390_k127_2628366_23	436308.Nmar_0492	1.287e-84	287.0	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
SRR25158390_k127_2628366_18	1459636.NTE_01012	4.453e-98	329.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158390_k127_2628366_5	1459636.NTE_01013	5.866e-172	549.0	COG0001@1|root,arCOG00918@2157|Archaea,41SDE@651137|Thaumarchaeota	651137|Thaumarchaeota	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_2628366_16	1131266.ARWQ01000005_gene821	5.442e-119	392.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158390_k127_2628366_13	1459636.NTE_01382	3.95e-134	439.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158390_k127_2628366_27	1459636.NTE_01383	2.034e-80	273.0	COG1648@1|root,arCOG01044@2157|Archaea,41SN9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
SRR25158390_k127_2628366_14	1459636.NTE_01091	6.777e-131	424.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158390_k127_2628366_46	1459636.NTE_01092	4.668e-36	138.0	COG2139@1|root,arCOG04129@2157|Archaea,41SRF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	-	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
SRR25158390_k127_2628366_47	1459636.NTE_01093	1.959e-35	137.0	COG1460@1|root,arCOG01016@2157|Archaea,41SQ1@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb4	-	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
SRR25158390_k127_2628366_28	1459636.NTE_01094	8.932e-78	265.0	COG1491@1|root,arCOG04130@2157|Archaea,41SGD@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein of unknown function (DUF655)	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
SRR25158390_k127_2628366_37	1459636.NTE_01095	4.664e-56	205.0	COG0030@1|root,arCOG04131@2157|Archaea,41SN0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158390_k127_2628366_42	1459636.NTE_01096	2.493e-44	166.0	COG2890@1|root,arCOG00109@2157|Archaea,41SSD@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158390_k127_2628366_6	1459636.NTE_01097	6.285e-168	532.0	COG0473@1|root,arCOG01163@2157|Archaea,41S5U@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158390_k127_2628366_35	1459636.NTE_01098	5.406e-60	213.0	arCOG08673@1|root,arCOG08673@2157|Archaea	1459636.NTE_01098|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_58	748449.Halha_1865	4.516e-19	91.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158390_k127_2628366_40	1459636.NTE_00620	1.147e-50	185.0	COG0681@1|root,arCOG01739@2157|Archaea,41SQ2@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158390_k127_2628366_10	1459636.NTE_01695	4.022e-156	500.0	COG1163@1|root,arCOG00358@2157|Archaea,41SAD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
SRR25158390_k127_2628366_33	1459636.NTE_01257	2.587e-66	231.0	arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_22	1459636.NTE_01256	3.504e-86	291.0	COG1478@1|root,arCOG02714@2157|Archaea,41SHA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
SRR25158390_k127_2628366_2	1459636.NTE_01255	1.266e-225	704.0	COG0065@1|root,arCOG01698@2157|Archaea,41S7A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158390_k127_2628366_29	1459636.NTE_01254	2.699e-77	261.0	COG0066@1|root,arCOG02230@2157|Archaea,41SIA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158390_k127_2628366_54	1459636.NTE_00429	2.736e-23	110.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_62	1459636.NTE_01273	1.261e-15	79.0	arCOG03899@1|root,arCOG03899@2157|Archaea	2157|Archaea	L	endonuclease	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	HNH,HNH_3
SRR25158390_k127_2628366_52	1459636.NTE_01696	7.456e-26	111.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158390_k127_2628366_26	1459636.NTE_01698	7.469e-81	278.0	COG1712@1|root,arCOG00254@2157|Archaea,41SGA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
SRR25158390_k127_2628366_9	1459636.NTE_01702	3.506e-158	503.0	COG0379@1|root,arCOG04459@2157|Archaea,41S6Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158390_k127_2628366_56	1459636.NTE_01699	8.307e-20	89.0	COG4919@1|root,arCOG04293@2157|Archaea,41SVI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S30	-	-	-	ko:K02983	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121	-	-	-	Ribosomal_S30
SRR25158390_k127_2628366_25	1459636.NTE_01703	2.253e-83	285.0	COG0157@1|root,arCOG01482@2157|Archaea,41SHI@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the catabolism of quinolinic acid (QA)	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158390_k127_2628366_57	1459636.NTE_01704	8.763e-20	90.0	COG2093@1|root,arCOG04077@2157|Archaea,41SVE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
SRR25158390_k127_2628366_20	1459636.NTE_01705	3.067e-95	315.0	COG1095@1|root,arCOG00675@2157|Archaea,41SGF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase	-	-	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
SRR25158390_k127_2628366_3	1459636.NTE_01706	4.534e-182	575.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158390_k127_2628366_45	1459636.NTE_01707	1.139e-38	150.0	COG1909@1|root,arCOG04076@2157|Archaea,41SNQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
SRR25158390_k127_2628366_50	1459636.NTE_02286	1.203e-27	115.0	arCOG08688@1|root,arCOG08688@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_65	1459636.NTE_01643	1.341e-12	68.0	arCOG10403@1|root,arCOG10403@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_61	1131266.ARWQ01000012_gene1609	8.01e-17	83.0	arCOG08666@1|root,arCOG08666@2157|Archaea,41SVR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_19	1459636.NTE_02310	7.618e-98	329.0	COG1052@1|root,arCOG01755@2157|Archaea,41T1D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_2628366_17	1459636.NTE_01295	7.722e-107	356.0	COG1415@1|root,arCOG04253@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
SRR25158390_k127_2628366_31	1158338.JNLJ01000005_gene1373	1.852e-71	251.0	COG0338@1|root,COG0338@2|Bacteria,2G4QA@200783|Aquificae	200783|Aquificae	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158390_k127_2628366_74	436308.Nmar_1194	0.0001032	45.0	arCOG08693@1|root,arCOG08693@2157|Archaea,41T7N@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_39	219305.MCAG_00296	1.389e-51	205.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158390_k127_2628366_41	68170.KL590558_gene5388	1.352e-45	183.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158390_k127_2628366_38	1459636.NTE_01989	6.082e-54	193.0	COG1832@1|root,arCOG04227@2157|Archaea,41SMT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158390_k127_2628366_70	243274.THEMA_08645	3.356e-07	59.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158390_k127_2628366_30	1459636.NTE_03538	1.245e-76	267.0	COG0506@1|root,arCOG06322@2157|Archaea,41SY1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158390_k127_2628366_1	1459636.NTE_02036	1.692e-242	753.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
SRR25158390_k127_2628366_8	1459636.NTE_01522	1.89e-163	524.0	COG1960@1|root,arCOG01707@2157|Archaea	2157|Archaea	I	COG1960 Acyl-CoA dehydrogenases	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158390_k127_2628366_24	1459636.NTE_02210	2.162e-83	285.0	COG0010@1|root,arCOG01700@2157|Archaea,41T23@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158390_k127_2628366_55	1131266.ARWQ01000002_gene639	6.564e-20	96.0	COG1917@1|root,arCOG03444@2157|Archaea,41SV4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_2628366_73	436308.Nmar_1016	2.305e-05	53.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2628366_7	1459636.NTE_03539	6.514e-167	539.0	COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158390_k127_2628366_12	1459636.NTE_01521	1.623e-135	441.0	COG0160@1|root,arCOG00915@2157|Archaea,41TBD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.76	ko:K00823,ko:K00836	ko00250,ko00260,ko00410,ko00640,ko00650,ko01100,ko01120,ko01210,ko01230,map00250,map00260,map00410,map00640,map00650,map01100,map01120,map01210,map01230	M00027,M00033	R00908,R01648,R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_2628366_36	1459636.NTE_00036	1.163e-56	203.0	COG0494@1|root,arCOG01073@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_2628366_60	436308.Nmar_0062	7.879e-17	86.0	COG0463@1|root,arCOG00894@2157|Archaea,41SAS@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158390_k127_2628366_63	1459636.NTE_03121	3.698e-15	77.0	arCOG06947@1|root,arCOG06947@2157|Archaea	2157|Archaea	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2,zf-C2H2_4
SRR25158390_k127_2628366_11	1459636.NTE_01711	3.981e-153	499.0	COG0277@1|root,arCOG00337@2157|Archaea,41T0E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158390_k127_2628366_21	1459636.NTE_00791	3.909e-90	314.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	2157|Archaea	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158390_k127_2630888_9	1459636.NTE_00759	3.791e-208	657.0	COG1027@1|root,COG1670@1|root,arCOG00842@2157|Archaea,arCOG01750@2157|Archaea,41S9C@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158390_k127_2630888_21	1459636.NTE_00618	3.207e-106	346.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
SRR25158390_k127_2630888_50	263820.PTO0208	0.0008195	42.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,241R4@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158390_k127_2630888_36	1459636.NTE_00614	2.471e-52	199.0	COG3875@1|root,arCOG02046@2157|Archaea,41SK4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2630888_30	1459636.NTE_00612	1.557e-74	253.0	COG0456@1|root,arCOG00833@2157|Archaea,41SIY@651137|Thaumarchaeota	651137|Thaumarchaeota	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158390_k127_2630888_24	1459636.NTE_00608	2.224e-95	319.0	COG2520@1|root,arCOG00033@2157|Archaea,41S7P@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Met-10+ like-protein	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
SRR25158390_k127_2630888_2	1131266.ARWQ01000015_gene746	3.214e-246	775.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
SRR25158390_k127_2630888_13	1459636.NTE_00604	1.824e-152	496.0	COG0260@1|root,arCOG04322@2157|Archaea,41SYD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158390_k127_2630888_1	1459636.NTE_00602	4.449e-263	818.0	COG0036@1|root,COG3959@1|root,arCOG01053@2157|Archaea,arCOG05046@2157|Archaea,41SBE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim,Transketolase_N
SRR25158390_k127_2630888_23	999411.HMPREF1092_00159	1.294e-97	328.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,36E9P@31979|Clostridiaceae	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158390_k127_2630888_22	1459636.NTE_00600	1.574e-102	337.0	COG0176@1|root,arCOG05061@2157|Archaea,41S99@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158390_k127_2630888_6	1459636.NTE_00599	2.5e-224	706.0	COG2304@1|root,arCOG02900@2157|Archaea,41SDY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2630888_17	1459636.NTE_00598	4.183e-124	402.0	COG0714@1|root,arCOG00441@2157|Archaea,41SDZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
SRR25158390_k127_2630888_11	1459636.NTE_02230	9.763e-191	606.0	COG2304@1|root,arCOG02900@2157|Archaea	2157|Archaea	O	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158390_k127_2630888_10	1459636.NTE_02229	4.209e-208	660.0	COG1239@1|root,arCOG00438@2157|Archaea	2157|Archaea	H	magnesium chelatase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5
SRR25158390_k127_2630888_33	1459636.NTE_02226	1.248e-64	224.0	COG0099@1|root,arCOG01722@2157|Archaea,41SIW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158390_k127_2630888_34	1459636.NTE_02225	1.855e-61	215.0	COG0522@1|root,arCOG04239@2157|Archaea,41SN3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
SRR25158390_k127_2630888_19	1459636.NTE_02224	2.521e-112	371.0	COG0640@1|root,arCOG03420@1|root,arCOG01687@2157|Archaea,arCOG03420@2157|Archaea	2157|Archaea	K	PFAM S-layer	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,S_layer_C
SRR25158390_k127_2630888_5	1459636.NTE_02223	6.681e-227	716.0	COG0449@1|root,arCOG00057@2157|Archaea,41SFG@651137|Thaumarchaeota	651137|Thaumarchaeota	M	TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158390_k127_2630888_20	1459636.NTE_01557	2.241e-111	371.0	COG2038@1|root,arCOG04272@2157|Archaea,41SD3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the UPF0284 family	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
SRR25158390_k127_2630888_27	1459636.NTE_01556	1.164e-83	282.0	arCOG00517@1|root,arCOG00517@2157|Archaea,41SHJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_2630888_31	1459636.NTE_01555	3.587e-69	242.0	COG0063@1|root,arCOG00018@2157|Archaea,41SHM@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
SRR25158390_k127_2630888_39	1459636.NTE_02634	7.658e-47	173.0	COG1591@1|root,arCOG00919@2157|Archaea,41SQP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
SRR25158390_k127_2630888_38	1459636.NTE_02633	9.276e-52	190.0	COG2178@1|root,arCOG04318@2157|Archaea,41SKR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
SRR25158390_k127_2630888_0	1459636.NTE_01631	0.0	1076.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S7I@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18594	ko00720,ko01120,map00720,map01120	-	R03157	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_2630888_35	1459636.NTE_02622	8.691e-56	196.0	COG0316@1|root,arCOG04560@2157|Archaea,41SKH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158390_k127_2630888_7	1459636.NTE_02631	1.127e-212	666.0	COG0334@1|root,arCOG01352@2157|Archaea,41S7T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_2630888_47	1459636.NTE_00825	9.616e-10	64.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158390_k127_2630888_12	1459636.NTE_01634	5.877e-178	567.0	COG0358@1|root,arCOG04281@2157|Archaea,41S75@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
SRR25158390_k127_2630888_28	1459636.NTE_01635	3.155e-80	273.0	COG1339@1|root,arCOG01904@2157|Archaea,41SG9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Domain of unknown function DUF120	-	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase
SRR25158390_k127_2630888_29	1459636.NTE_01636	6.782e-75	258.0	COG0615@1|root,arCOG03924@1|root,arCOG01222@2157|Archaea,arCOG03924@2157|Archaea,41SPR@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Cytidylyltransferase-like	-	-	2.7.7.2,2.7.7.39	ko:K00980,ko:K14656	ko00564,ko00740,ko01100,ko01110,map00564,map00740,map01100,map01110	-	R00161,R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158390_k127_2630888_43	1459636.NTE_02686	7.918e-25	104.0	arCOG08817@1|root,arCOG08817@2157|Archaea,41SV5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2630888_44	1501391.LG35_00020	1.05e-17	89.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,2FMP2@200643|Bacteroidia,22VD5@171550|Rikenellaceae	976|Bacteroidetes	K	Transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_2630888_18	1459636.NTE_02687	3.368e-122	398.0	COG0037@1|root,arCOG00042@2157|Archaea,41S84@651137|Thaumarchaeota	651137|Thaumarchaeota	D	PP-loop family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
SRR25158390_k127_2630888_14	1459636.NTE_02703	4.791e-147	471.0	COG1736@1|root,arCOG04112@2157|Archaea,41SE0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Diphthamide biosynthesis	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
SRR25158390_k127_2630888_26	1459636.NTE_03213	6.136e-86	292.0	COG0294@1|root,arCOG02817@2157|Archaea,41SGK@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158390_k127_2630888_4	1459636.NTE_03212	2.401e-240	749.0	COG0516@1|root,arCOG00612@2157|Archaea,41S7R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158390_k127_2630888_45	1459636.NTE_02161	6.34e-17	82.0	COG1958@1|root,arCOG00998@2157|Archaea,41SU9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
SRR25158390_k127_2630888_41	1459636.NTE_02685	4.021e-34	135.0	COG1786@1|root,arCOG04279@2157|Archaea,41SPA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
SRR25158390_k127_2630888_16	1459636.NTE_02684	9.681e-129	421.0	COG1679@1|root,arCOG04278@2157|Archaea,41SBC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
SRR25158390_k127_2630888_25	1459636.NTE_03217	1.835e-88	298.0	COG1634@1|root,arCOG04303@2157|Archaea,41SKX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
SRR25158390_k127_2630888_40	1459636.NTE_03219	1.164e-40	158.0	arCOG05463@1|root,arCOG05463@2157|Archaea,41SR3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2630888_3	1459636.NTE_03220	4.376e-243	759.0	COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158390_k127_2630888_46	1459636.NTE_02806	5.044e-11	64.0	arCOG10404@1|root,arCOG10404@2157|Archaea	1459636.NTE_02806|-	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2630888_37	1459636.NTE_02430	3.928e-52	199.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158390_k127_2630888_15	1459636.NTE_01652	1.034e-130	436.0	COG4257@1|root,arCOG03564@2157|Archaea,41SM7@651137|Thaumarchaeota	651137|Thaumarchaeota	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SRR25158390_k127_2630888_42	1131266.ARWQ01000014_gene96	6.591e-31	127.0	COG0346@1|root,arCOG02708@2157|Archaea,41T5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_2630888_8	1459636.NTE_02924	5.406e-210	666.0	COG1205@1|root,arCOG00555@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158390_k127_2639900_0	1128421.JAGA01000002_gene335	9.732e-84	294.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158390_k127_2639900_2	6326.BUX.s00351.234	4.662e-05	53.0	KOG1565@1|root,KOG1565@2759|Eukaryota,3A7FM@33154|Opisthokonta,3BTV2@33208|Metazoa,3DAHQ@33213|Bilateria,40EDQ@6231|Nematoda,1KWH4@119089|Chromadorea	33208|Metazoa	O	Belongs to the peptidase M10A family	-	GO:0002164,GO:0002682,GO:0002684,GO:0002831,GO:0002833,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0006950,GO:0006952,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008340,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009791,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0010259,GO:0010286,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0016787,GO:0018996,GO:0019222,GO:0019538,GO:0022404,GO:0031323,GO:0031324,GO:0031347,GO:0031349,GO:0031399,GO:0031400,GO:0032101,GO:0032103,GO:0032268,GO:0032269,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032386,GO:0032387,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033157,GO:0040012,GO:0040017,GO:0042303,GO:0042306,GO:0042308,GO:0042395,GO:0042742,GO:0043170,GO:0043207,GO:0043900,GO:0043902,GO:0044238,GO:0045088,GO:0045089,GO:0046822,GO:0046823,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048856,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050795,GO:0050829,GO:0050896,GO:0051049,GO:0051050,GO:0051051,GO:0051171,GO:0051172,GO:0051223,GO:0051224,GO:0051246,GO:0051248,GO:0051704,GO:0051707,GO:0060255,GO:0060259,GO:0060341,GO:0060620,GO:0065007,GO:0070011,GO:0070201,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090317,GO:0098542,GO:0140096,GO:1900034,GO:1900036,GO:1900180,GO:1900181,GO:1900424,GO:1900426,GO:1901564,GO:1902477,GO:1902479,GO:1903426,GO:1903427,GO:1903827,GO:1903828,GO:1903998,GO:1904000,GO:1904109,GO:1904589,GO:1904590,GO:1904806,GO:1904807,GO:1904950,GO:1905952,GO:1905954,GO:2000241,GO:2000243,GO:2000253,GO:2000377,GO:2000378,GO:2000909,GO:2000911	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SRR25158390_k127_2640385_10	595460.RRSWK_01413	3.726e-05	47.0	COG2911@1|root,COG2931@1|root,COG5492@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG5492@2|Bacteria,2IZWN@203682|Planctomycetes	203682|Planctomycetes	Q	HemY domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2640385_6	1229909.NSED_08245	5.479e-12	70.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2640385_8	1313421.JHBV01000155_gene784	7.246e-08	63.0	28MC2@1|root,2ZAQD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2640385_11	491205.JARQ01000007_gene3196	0.0009359	48.0	COG0266@1|root,COG0266@2|Bacteria,4NH8P@976|Bacteroidetes,1HZMI@117743|Flavobacteriia,3ZP4J@59732|Chryseobacterium	976|Bacteroidetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158390_k127_2640385_7	1267533.KB906733_gene3018	6.963e-08	55.0	COG0266@1|root,COG0266@2|Bacteria,3Y2WM@57723|Acidobacteria,2JIQF@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158390_k127_2640385_9	1198114.AciX9_0954	1.627e-06	52.0	COG0266@1|root,COG0266@2|Bacteria,3Y3PM@57723|Acidobacteria,2JIJT@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158390_k127_2640385_5	420324.KI912026_gene4978	4.111e-18	92.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HemolysinCabind,LTD
SRR25158390_k127_2640385_0	1131266.ARWQ01000002_gene632	1.146e-153	490.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	2157|Archaea	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384,ko:K03387	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158390_k127_2640385_1	521011.Mpal_1474	3.716e-59	220.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_2640385_2	1459636.NTE_00421	1.05e-39	149.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
SRR25158390_k127_2640385_3	1459636.NTE_01719	1.825e-23	102.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T4V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_2652583_0	1041146.ATZB01000034_gene562	1.182e-133	439.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2TR2U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_2652583_1	686340.Metal_2216	6.716e-19	94.0	2C5IF@1|root,2Z9B7@2|Bacteria,1R5AB@1224|Proteobacteria,1SJEE@1236|Gammaproteobacteria,1XGBF@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1264
SRR25158390_k127_2664239_1	1131266.ARWQ01000004_gene1476	8.756e-60	216.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2664239_4	398767.Glov_0114	2.119e-06	53.0	COG0500@1|root,COG2226@2|Bacteria,1QZV0@1224|Proteobacteria,43CPF@68525|delta/epsilon subdivisions,2WS28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158390_k127_2664239_0	1459636.NTE_03048	2.811e-65	231.0	COG1938@1|root,arCOG00347@2157|Archaea,41T2Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158390_k127_2664239_2	247490.KSU1_C1274	1.703e-25	123.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_2664239_3	1353276.JADR01000001_gene281	3.326e-12	79.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
SRR25158390_k127_2669365_2	1056495.Calag_1008	1.514e-68	241.0	COG1573@1|root,arCOG00905@2157|Archaea,2XRWR@28889|Crenarchaeota	28889|Crenarchaeota	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158390_k127_2669365_5	1408424.JHYI01000018_gene3187	5.249e-18	85.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
SRR25158390_k127_2669365_0	1459636.NTE_00914	3.63e-140	464.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158390_k127_2669365_3	443254.Marpi_0823	1.258e-41	168.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SRR25158390_k127_2669365_6	1056512.D515_03281	4.041e-16	87.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,DUF642,HemolysinCabind,Peptidase_M10,Peptidase_M10_C
SRR25158390_k127_2669365_4	1459636.NTE_01449	3.386e-27	117.0	COG0494@1|root,COG1853@1|root,arCOG01083@2157|Archaea,arCOG02017@2157|Archaea	2157|Archaea	L	PFAM flavin reductase domain protein, FMN-binding	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016722,GO:0016723,GO:0032553,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.16.1.10,3.6.1.55	ko:K03574,ko:K18915	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Flavin_Reduct,NUDIX
SRR25158390_k127_2669365_8	211165.AJLN01000085_gene1571	4.653e-13	76.0	COG0515@1|root,COG0515@2|Bacteria,1G0M9@1117|Cyanobacteria,1JJCN@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,PsbP
SRR25158390_k127_2669365_1	204669.Acid345_4475	3.283e-111	380.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158390_k127_2669365_7	290317.Cpha266_1549	1.161e-13	76.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158390_k127_2710982_0	1459636.NTE_02848	3.181e-62	221.0	arCOG08811@1|root,arCOG08811@2157|Archaea,41T85@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2710982_2	1459636.NTE_02847	5.844e-36	153.0	arCOG06267@1|root,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	2157|Archaea	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158390_k127_2710982_4	1459636.NTE_02847	2.111e-23	109.0	arCOG06267@1|root,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	2157|Archaea	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158390_k127_2808252_2	913865.DOT_2970	4.706e-06	51.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes	1239|Firmicutes	T	response regulator, receiver	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158390_k127_2808252_0	521011.Mpal_1345	1.326e-85	293.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_2808252_3	1229909.NSED_01775	0.0004054	48.0	COG2314@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG03293@2157|Archaea	2157|Archaea	O	PFAM TM2 domain containing protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DZR,DnaJ,TM2
SRR25158390_k127_2808252_1	1459636.NTE_01614	3.997e-12	70.0	COG1241@1|root,arCOG00439@2157|Archaea	2157|Archaea	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_OB
SRR25158390_k127_287005_0	484770.UFO1_3568	2.231e-40	161.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4H897@909932|Negativicutes	909932|Negativicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158390_k127_290953_4	1459636.NTE_00263	3.603e-42	160.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T43@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_290953_6	1121447.JONL01000008_gene3431	4.392e-13	73.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,43BTN@68525|delta/epsilon subdivisions,2X74J@28221|Deltaproteobacteria,2MB6C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_290953_5	526222.Desal_3740	2.383e-32	133.0	COG0596@1|root,COG0596@2|Bacteria,1QW7Y@1224|Proteobacteria,43D1K@68525|delta/epsilon subdivisions,2X89J@28221|Deltaproteobacteria,2MHE2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158390_k127_290953_0	350058.Mvan_5450	1.147e-121	399.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,238G3@1762|Mycobacteriaceae	201174|Actinobacteria	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_290953_7	1297863.APJF01000013_gene4092	3.114e-09	61.0	COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria,2U9XS@28211|Alphaproteobacteria,3JZUN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158390_k127_290953_1	706587.Desti_3287	6.287e-64	225.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,43CIK@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	DJ-1/PfpI family	inhA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158390_k127_290953_2	1459636.NTE_02786	1.548e-63	220.0	COG4275@1|root,arCOG10427@2157|Archaea	2157|Archaea	S	Chromate resistance	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158390_k127_290953_3	983544.Lacal_2774	1.471e-60	226.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,1HZ8C@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
SRR25158390_k127_290953_8	1459636.NTE_02627	1.74e-06	51.0	arCOG00516@1|root,arCOG00516@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158390_k127_29225_5	748449.Halha_0139	4.468e-38	154.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WAXE@53433|Halanaerobiales	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158390_k127_29225_2	1459636.NTE_01981	2.683e-87	306.0	COG2379@1|root,arCOG04170@2157|Archaea,41SJF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158390_k127_29225_4	1459636.NTE_01975	5.641e-45	167.0	COG4911@1|root,arCOG05495@2157|Archaea,41SNJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158390_k127_29225_3	1459636.NTE_01973	5.022e-84	288.0	COG1575@1|root,arCOG00480@2157|Archaea,41S8H@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158390_k127_29225_7	1459636.NTE_00107	6.939e-09	58.0	arCOG08792@1|root,arCOG08792@2157|Archaea,41SUG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_29225_6	1131266.ARWQ01000002_gene493	5.846e-16	79.0	arCOG04508@1|root,arCOG04508@2157|Archaea,41SVW@651137|Thaumarchaeota	651137|Thaumarchaeota	P	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
SRR25158390_k127_29225_0	1459636.NTE_02181	8.721e-129	422.0	COG1063@1|root,arCOG01459@2157|Archaea,41S98@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_29225_1	1459636.NTE_02180	2.051e-92	305.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158390_k127_2943025_2	1131266.ARWQ01000004_gene1476	2.382e-19	89.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2943025_0	1459636.NTE_03190	1.627e-89	303.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158390_k127_2943025_1	227086.JGI_V11_85451	1.953e-24	111.0	COG4122@1|root,KOG1663@2759|Eukaryota	2759|Eukaryota	P	O-methyltransferase activity	comt-1	-	2.1.1.6	ko:K00545	ko00140,ko00350,ko00965,ko01100,ko04728,map00140,map00350,map00965,map01100,map04728	-	R02534,R02920,R03304,R04301,R04762,R04764,R04881,R04887	RC00003,RC00392	ko00000,ko00001,ko01000,ko04147	-	-	-	DUF3752,DnaJ,Methyltransf_24,Methyltransf_3
SRR25158390_k127_2970030_4	1196029.ALIM01000049_gene4541	1.409e-21	98.0	COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus	91061|Bacilli	C	Cytochrome P450	yjiB	GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	1.14.14.46	ko:K16593	ko00780,ko01100,map00780,map01100	M00573	R10123	-	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_2970030_2	521011.Mpal_1474	3.001e-77	272.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158390_k127_2970030_5	1448389.BAVQ01000002_gene2942	5.694e-10	61.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria	201174|Actinobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158390_k127_2970030_1	1459636.NTE_02202	8.962e-98	331.0	COG1018@1|root,COG2146@1|root,arCOG02200@2157|Archaea,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	DAO,FAD_binding_6,NAD_binding_1,Rieske,Rieske_2
SRR25158390_k127_2970030_6	1229909.NSED_05590	6.486e-08	58.0	arCOG03622@1|root,arCOG03622@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2970030_3	1459636.NTE_03221	3.246e-57	210.0	COG0500@1|root,arCOG01783@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158390_k127_2970030_0	525904.Tter_1226	1.743e-111	368.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158390_k127_2975220_2	1121904.ARBP01000002_gene6919	4.232e-07	51.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes,47M70@768503|Cytophagia	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158390_k127_2975220_1	439481.Aboo_0904	1.754e-135	441.0	COG1228@1|root,arCOG00696@2157|Archaea,2XVAU@28890|Euryarchaeota,3F2Z2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_2975220_0	1459636.NTE_02849	6.999e-199	654.0	COG4257@1|root,arCOG06267@1|root,arCOG03564@2157|Archaea,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	651137|Thaumarchaeota	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158390_k127_2979760_0	1459636.NTE_00079	0.0	1278.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
SRR25158390_k127_2979760_1	1459636.NTE_03553	1.995e-230	719.0	COG0112@1|root,arCOG00070@2157|Archaea,41S7U@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158390_k127_2979760_11	1459636.NTE_01386	1.314e-29	123.0	COG0350@1|root,arCOG02724@2157|Archaea,41SR8@651137|Thaumarchaeota	651137|Thaumarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158390_k127_2979760_12	1459636.NTE_02871	2.838e-26	111.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
SRR25158390_k127_2979760_16	436308.Nmar_0853	7.758e-16	83.0	COG0346@1|root,arCOG02708@2157|Archaea,41SU3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158390_k127_2979760_15	1370122.JHXQ01000002_gene2851	1.243e-21	100.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BCXZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase2,He_PIG,HemolysinCabind
SRR25158390_k127_2979760_19	269797.Mbar_A2815	0.0006314	45.0	COG0225@1|root,arCOG02816@2157|Archaea,2XWKA@28890|Euryarchaeota,2N9M6@224756|Methanomicrobia	224756|Methanomicrobia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158390_k127_2979760_3	481448.Minf_0851	1.163e-108	364.0	2C6Q3@1|root,2Z7T4@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR25158390_k127_2979760_2	481448.Minf_0852	3.54e-187	604.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR25158390_k127_2979760_14	1379698.RBG1_1C00001G1268	1.808e-23	114.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158390_k127_2979760_13	391623.TERMP_01864	2.513e-24	120.0	COG0419@1|root,arCOG00368@2157|Archaea,2XTC7@28890|Euryarchaeota,244YZ@183968|Thermococci	183968|Thermococci	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_21,Rad50_zn_hook
SRR25158390_k127_2979760_6	1041930.Mtc_1149	1.186e-78	276.0	COG0530@1|root,arCOG02881@2157|Archaea,2Y2BH@28890|Euryarchaeota,2NAGG@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158390_k127_2979760_4	1459636.NTE_02504	6.952e-97	331.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_2979760_5	1304885.AUEY01000014_gene3322	2.971e-87	306.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
SRR25158390_k127_2979760_7	1459636.NTE_00594	2.691e-57	204.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2979760_10	1459636.NTE_00594	1.846e-45	170.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2979760_8	1459636.NTE_03298	1.371e-50	187.0	arCOG08024@1|root,arCOG08024@2157|Archaea,41SRU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158390_k127_2979760_17	1459636.NTE_03299	2.578e-06	49.0	arCOG08025@1|root,arCOG08025@2157|Archaea,41STV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158390_k127_2987760_8	468059.AUHA01000003_gene2054	6.84e-05	53.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1IRMS@117747|Sphingobacteriia	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158390_k127_2987760_2	1459636.NTE_01296	5.403e-43	158.0	COG2146@1|root,arCOG02852@2157|Archaea,41SSE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158390_k127_2987760_5	1459636.NTE_03100	1.625e-12	69.0	COG1872@1|root,arCOG04058@2157|Archaea,41TAX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158390_k127_2987760_0	944481.JAFP01000001_gene373	4.989e-65	224.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2M75M@213113|Desulfurellales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158390_k127_2987760_7	1459636.NTE_03514	8.409e-06	48.0	COG1055@1|root,arCOG00238@2157|Archaea,41SZM@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SRR25158390_k127_2987760_3	1459636.NTE_00888	3.791e-29	123.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_2987760_4	1229909.NSED_03525	4.259e-28	116.0	COG1055@1|root,arCOG00238@2157|Archaea,41SZM@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SRR25158390_k127_2988641_1	1459636.NTE_01491	2.146e-23	104.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2988641_2	1267533.KB906736_gene1024	1.169e-12	75.0	arCOG11428@1|root,33YIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2988641_0	1459636.NTE_01491	9.205e-25	108.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_2992523_1	1122135.KB893135_gene935	3.425e-30	126.0	2DBY8@1|root,2ZBU3@2|Bacteria	2|Bacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158390_k127_2992523_0	436308.Nmar_1661	1.567e-42	160.0	COG1733@1|root,arCOG01057@2157|Archaea,41T7C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_2992523_2	1459636.NTE_00325	8.375e-13	69.0	COG2149@1|root,arCOG05380@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158390_k127_3006519_11	1122605.KB893646_gene125	1.676e-15	82.0	COG0739@1|root,COG0739@2|Bacteria,4NPNT@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158390_k127_3006519_16	489825.LYNGBM3L_57810	0.0001375	50.0	COG3161@1|root,COG3161@2|Bacteria,1G5KJ@1117|Cyanobacteria	1117|Cyanobacteria	H	Protein of unknown function (DUF98)	-	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF98
SRR25158390_k127_3006519_3	1459636.NTE_02280	1.913e-69	243.0	COG1575@1|root,arCOG00480@2157|Archaea,41SNA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3006519_7	1229909.NSED_00455	7.136e-40	156.0	COG0500@1|root,arCOG04347@2157|Archaea,41SQN@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Nodulation protein S (NodS)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158390_k127_3006519_14	1459636.NTE_03191	1.612e-06	51.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_3006519_10	1459636.NTE_01164	2.237e-22	105.0	arCOG00144@1|root,arCOG11894@1|root,arCOG00144@2157|Archaea,arCOG11894@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_3006519_8	1459636.NTE_01164	8.741e-36	141.0	arCOG00144@1|root,arCOG11894@1|root,arCOG00144@2157|Archaea,arCOG11894@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_3006519_1	1459636.NTE_00865	4.405e-154	493.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158390_k127_3006519_4	1459636.NTE_00866	2.276e-65	229.0	COG1392@1|root,arCOG02640@2157|Archaea,41SKJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158390_k127_3006519_5	1459636.NTE_01186	1.484e-58	210.0	COG1878@1|root,arCOG02462@2157|Archaea,41SK8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158390_k127_3006519_6	1459636.NTE_03520	3.444e-51	192.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3006519_2	1183377.Py04_0032	1.332e-112	391.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,243CX@183968|Thermococci	183968|Thermococci	L	ERCC4 domain	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,Helicase_C
SRR25158390_k127_3006519_0	1459636.NTE_03346	3.407e-162	522.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	rad25	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158390_k127_3006519_15	1459636.NTE_02174	8.332e-06	52.0	COG1715@1|root,arCOG02777@2157|Archaea	2157|Archaea	V	restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
SRR25158390_k127_3015606_6	1459636.NTE_01106	5.98e-05	46.0	COG0367@1|root,arCOG04741@1|root,arCOG00071@2157|Archaea,arCOG04741@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRR25158390_k127_3015606_2	1459636.NTE_01786	8.519e-32	126.0	arCOG08697@1|root,arCOG08697@2157|Archaea,41SUN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3015606_0	1459636.NTE_01785	1.173e-226	708.0	COG0498@1|root,arCOG01434@2157|Archaea,41S5N@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_3015606_1	1459636.NTE_01784	3.256e-170	548.0	COG0147@1|root,arCOG02014@2157|Archaea,41S8W@651137|Thaumarchaeota	651137|Thaumarchaeota	E	component I	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158390_k127_3015606_3	1459636.NTE_02704	1.658e-27	113.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3015606_4	1459636.NTE_01697	1.114e-21	96.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158390_k127_3073359_1	1459636.NTE_01477	9.194e-25	106.0	COG1970@1|root,arCOG05213@2157|Archaea	2157|Archaea	M	Large-conductance mechanosensitive channel, MscL	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158390_k127_3073359_3	1229909.NSED_08795	4.168e-17	86.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158390_k127_3073359_5	68223.JNZY01000009_gene3132	3.634e-05	54.0	29WIT@1|root,30I51@2|Bacteria,2GZTF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3073359_0	1459636.NTE_03453	1.005e-65	233.0	COG0596@1|root,arCOG07416@1|root,arCOG01648@2157|Archaea,arCOG07416@2157|Archaea	2157|Archaea	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_3073359_4	4787.PITG_01181T0	8.134e-12	70.0	COG0526@1|root,KOG2699@1|root,KOG0907@2759|Eukaryota,KOG2699@2759|Eukaryota,3QBRY@4776|Peronosporales	4776|Peronosporales	O	PUB domain	-	-	-	-	-	-	-	-	-	-	-	-	PUB,Thioredoxin,UBA
SRR25158390_k127_3073359_2	243231.GSU1723	1.326e-24	116.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria,43S3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158390_k127_3073359_6	1121468.AUBR01000024_gene3040	0.000642	49.0	COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,24QQ6@186801|Clostridia,42H8S@68295|Thermoanaerobacterales	186801|Clostridia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3073892_0	1459636.NTE_01650	6.963e-36	139.0	COG1581@1|root,arCOG01753@2157|Archaea	2157|Archaea	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
SRR25158390_k127_3073892_1	546273.VEIDISOL_01947	5.564e-07	55.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,4H38S@909932|Negativicutes	909932|Negativicutes	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_3120573_0	1459636.NTE_02436	4.598e-72	260.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
SRR25158390_k127_3120573_1	1229909.NSED_08970	1.393e-16	86.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41T50@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_31337_2	273057.SSO2006	3.845e-09	63.0	COG3335@1|root,arCOG02127@2157|Archaea	2157|Archaea	L	Homeodomain-like domain	-	-	-	ko:K07494,ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
SRR25158390_k127_31337_1	1536772.R70723_11820	7.439e-10	66.0	COG3335@1|root,COG3335@2|Bacteria,1V41H@1239|Firmicutes,4HH52@91061|Bacilli,26WN7@186822|Paenibacillaceae	91061|Bacilli	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR25158390_k127_31337_0	1459636.NTE_02123	5.913e-41	170.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158390_k127_3163337_0	679926.Mpet_2328	1.452e-10	67.0	COG3039@1|root,arCOG02751@2157|Archaea,2XTDW@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_3182204_6	1459636.NTE_01046	3.454e-25	106.0	arCOG02240@1|root,arCOG02240@2157|Archaea	2157|Archaea	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase,Tautomerase_2
SRR25158390_k127_3182204_2	523791.Kkor_0590	7.735e-77	269.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3182204_3	1459636.NTE_01001	1.954e-68	246.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3182204_1	1459636.NTE_01021	1.621e-88	305.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_3182204_9	1459636.NTE_02294	9.888e-10	59.0	COG1321@1|root,arCOG02100@2157|Archaea,41SQ9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
SRR25158390_k127_3182204_11	436308.Nmar_1664	2.939e-05	48.0	COG1321@1|root,arCOG02100@2157|Archaea,41SQ9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
SRR25158390_k127_3182204_4	1459636.NTE_01632	2.152e-64	228.0	COG0518@1|root,arCOG00090@2157|Archaea,41T3Z@651137|Thaumarchaeota	651137|Thaumarchaeota	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158390_k127_3182204_8	1201290.M902_2411	8.055e-12	71.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2MSQK@213481|Bdellovibrionales,2WKRY@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158390_k127_3182204_0	436308.Nmar_0011	4.767e-285	893.0	COG0464@1|root,arCOG01308@2157|Archaea,41SX8@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158390_k127_3182204_5	1459636.NTE_00353	6.336e-64	223.0	COG0071@1|root,arCOG01833@2157|Archaea,41SPJ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158390_k127_3182204_7	1229909.NSED_05640	2.793e-17	85.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158390_k127_3187193_0	1459636.NTE_03523	2.758e-98	339.0	COG3391@1|root,arCOG08716@1|root,arCOG02562@2157|Archaea,arCOG08716@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PKD
SRR25158390_k127_3203598_0	1459636.NTE_00844	6.697e-71	245.0	COG1335@1|root,arCOG01943@2157|Archaea	2157|Archaea	Q	COG1335 Amidases related to nicotinamidase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158390_k127_3203598_1	693661.Arcve_0910	6.892e-63	226.0	arCOG02754@1|root,arCOG02754@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_3208238_0	78245.Xaut_4995	6.096e-11	69.0	COG3335@1|root,COG3335@2|Bacteria,1Q66S@1224|Proteobacteria,2UR2V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR25158390_k127_327831_14	1122603.ATVI01000005_gene3827	1.416e-10	67.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSI4@1236|Gammaproteobacteria,1XD7U@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SRR25158390_k127_327831_4	1459636.NTE_00848	4.564e-49	179.0	arCOG03910@1|root,arCOG03910@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_327831_1	1459636.NTE_00548	4.575e-89	296.0	COG0225@1|root,arCOG02816@2157|Archaea,41SMP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158390_k127_327831_5	1459636.NTE_00549	2.589e-44	162.0	COG0229@1|root,arCOG02815@2157|Archaea	2157|Archaea	O	COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158390_k127_327831_15	1459636.NTE_00549	1.405e-09	61.0	COG0229@1|root,arCOG02815@2157|Archaea	2157|Archaea	O	COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158390_k127_327831_17	865937.Gilli_1805	0.0003476	48.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia,2P6DS@244698|Gillisia	976|Bacteroidetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
SRR25158390_k127_327831_9	1459636.NTE_02711	5.424e-22	98.0	COG3224@1|root,arCOG08661@2157|Archaea	2157|Archaea	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
SRR25158390_k127_327831_3	1459636.NTE_02269	7.95e-67	233.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158390_k127_327831_6	1459636.NTE_01667	7.309e-38	145.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_327831_8	44689.DDB0232283	1.139e-30	136.0	COG1112@1|root,KOG1803@2759|Eukaryota,3XC2W@554915|Amoebozoa	554915|Amoebozoa	A	R3H domain	-	-	3.6.4.12,3.6.4.13	ko:K19036	-	-	-	-	ko00000,ko01000,ko03009,ko03012	-	-	-	AAA_12,R3H,zf-AN1
SRR25158390_k127_327831_2	1459636.NTE_01998	3.325e-70	241.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_327831_0	1459636.NTE_03330	2.459e-113	374.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	2157|Archaea	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_327831_11	1459636.NTE_03333	1.284e-15	86.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
SRR25158390_k127_327831_7	1459636.NTE_01281	5.576e-37	142.0	COG0526@1|root,arCOG01972@2157|Archaea,41SSR@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_327831_13	1089547.KB913013_gene652	3.084e-13	75.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,47JWS@768503|Cytophagia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158390_k127_327831_16	1449044.JMLE01000002_gene4295	5.096e-06	55.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,1W7Y5@1268|Micrococcaceae	201174|Actinobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158390_k127_327831_10	1459636.NTE_00991	2.025e-19	90.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_00991|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3291333_0	1459636.NTE_01908	6.85e-157	499.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
SRR25158390_k127_3291333_4	368408.Tpen_0769	5.272e-05	48.0	COG0640@1|root,arCOG03859@2157|Archaea	2157|Archaea	K	ligase activity	-	-	-	ko:K00666,ko:K03892	-	-	-	-	ko00000,ko01000,ko01004,ko03000	-	-	-	HTH_20,HTH_5
SRR25158390_k127_3291333_1	1459636.NTE_01573	1.342e-20	93.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_3291333_3	215358.XP_010730378.1	1.393e-07	61.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata,496SD@7742|Vertebrata,4A6IB@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
SRR25158390_k127_3291333_2	1459636.NTE_01553	9.453e-11	63.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3311369_2	1298863.AUEP01000003_gene2968	1.66e-10	71.0	2C7PU@1|root,33JNE@2|Bacteria,2GZ9R@201174|Actinobacteria	201174|Actinobacteria	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
SRR25158390_k127_3311369_0	644966.Tmar_1896	1.183e-46	182.0	COG3547@1|root,COG3547@2|Bacteria,1VI3C@1239|Firmicutes,25AXZ@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_3311369_1	319795.Dgeo_2191	2.577e-33	141.0	2DBFF@1|root,2Z8YA@2|Bacteria	2|Bacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR25158390_k127_332913_0	1459636.NTE_00046	1.666e-139	451.0	COG0226@1|root,arCOG08033@1|root,arCOG00213@2157|Archaea,arCOG08033@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158390_k127_332913_2	1459636.NTE_00042	4.998e-83	282.0	COG0704@1|root,arCOG00232@2157|Archaea,41T42@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158390_k127_332913_1	1459636.NTE_00041	3.706e-123	404.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
SRR25158390_k127_332913_3	1459636.NTE_00044	6.226e-38	144.0	COG0581@1|root,arCOG00168@2157|Archaea,41SZ4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_3404133_1	436308.Nmar_1637	3.262e-15	87.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3404133_3	1408444.JHYC01000011_gene998	1.553e-08	57.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,1JD2W@118969|Legionellales	118969|Legionellales	C	Zinc-binding dehydrogenase	yahK	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_3404133_0	1459636.NTE_00373	1.815e-82	286.0	COG2124@1|root,arCOG02814@2157|Archaea	2157|Archaea	C	cytochrome P450	cyp119	-	1.11.1.7,1.14.14.1	ko:K00493,ko:K21201	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158390_k127_345814_34	1459636.NTE_00200	7.08e-08	60.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345814_35	1459636.NTE_00200	0.0004156	47.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345814_29	1459636.NTE_00723	3.576e-44	163.0	COG0361@1|root,arCOG01179@2157|Archaea,41SRK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	-	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
SRR25158390_k127_345814_10	1459636.NTE_03204	7.02e-127	411.0	COG0107@1|root,arCOG00617@2157|Archaea,41S9A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158390_k127_345814_20	1459636.NTE_03203	1.072e-72	252.0	COG0106@1|root,arCOG00618@2157|Archaea,41SIG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158390_k127_345814_16	1459636.NTE_03202	2.796e-81	276.0	COG0118@1|root,arCOG00089@2157|Archaea,41SY2@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158390_k127_345814_17	1459636.NTE_03201	1.377e-74	255.0	COG0131@1|root,arCOG04398@2157|Archaea,41SGY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158390_k127_345814_18	1459636.NTE_03198	3.159e-74	261.0	COG0546@1|root,arCOG04692@2157|Archaea,41SJ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR25158390_k127_345814_15	1459636.NTE_03197	1.211e-93	318.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158390_k127_345814_13	1229909.NSED_00715	1.146e-117	392.0	COG0141@1|root,arCOG04352@2157|Archaea,41S6J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158390_k127_345814_5	1459636.NTE_03195	2.415e-156	498.0	COG0040@1|root,arCOG02208@2157|Archaea,41SCJ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ATP phosphoribosyltransferase	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158390_k127_345814_6	1459636.NTE_03194	9.553e-147	477.0	COG1257@1|root,arCOG04260@2157|Archaea,41SAU@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
SRR25158390_k127_345814_9	1459636.NTE_03188	3.019e-142	460.0	COG2133@1|root,arCOG02796@2157|Archaea,41S7F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158390_k127_345814_7	1459636.NTE_03161	1.737e-145	469.0	COG0399@1|root,arCOG00118@2157|Archaea,41S96@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158390_k127_345814_3	1459636.NTE_03162	7.413e-184	583.0	COG0004@1|root,arCOG04397@2157|Archaea,41SZ0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158390_k127_345814_14	1459636.NTE_03164	8.079e-99	323.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_345814_19	1459636.NTE_03154	3.256e-73	248.0	COG1601@1|root,arCOG01640@2157|Archaea,41STZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor	-	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	eIF-5_eIF-2B
SRR25158390_k127_345814_28	1459636.NTE_03150	2.998e-44	164.0	COG0526@1|root,arCOG01972@2157|Archaea	2157|Archaea	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158390_k127_345814_27	1459636.NTE_03149	2.362e-47	177.0	COG0576@1|root,arCOG04772@2157|Archaea,41SSU@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158390_k127_345814_0	1459636.NTE_03148	4.224e-313	968.0	COG0443@1|root,arCOG03060@2157|Archaea,41SCM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158390_k127_345814_4	1459636.NTE_03147	1.634e-160	513.0	COG0484@1|root,arCOG06880@1|root,arCOG02846@2157|Archaea,arCOG06880@2157|Archaea,41SCZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ central domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158390_k127_345814_33	237368.SCABRO_01742	1.454e-11	68.0	COG4095@1|root,COG4095@2|Bacteria,2J3PM@203682|Planctomycetes	203682|Planctomycetes	S	PQ loop repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345814_32	1459636.NTE_00083	3.653e-29	122.0	arCOG04038@1|root,arCOG04038@2157|Archaea,41SQU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345814_23	1459636.NTE_00035	2.732e-50	184.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345814_8	1459636.NTE_00059	1.686e-142	464.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158390_k127_345814_2	1459636.NTE_01032	8.575e-205	649.0	COG0661@1|root,arCOG01189@2157|Archaea,41SYQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158390_k127_345814_30	1459636.NTE_01033	5.819e-39	149.0	arCOG03681@1|root,arCOG03681@2157|Archaea,41T6V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_345814_22	1459636.NTE_01034	8.446e-53	191.0	COG0494@1|root,arCOG01073@2157|Archaea,41T73@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158390_k127_345814_26	1459636.NTE_00454	6.569e-48	173.0	COG1308@1|root,arCOG04061@2157|Archaea,41SNN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
SRR25158390_k127_345814_24	1459636.NTE_00453	1.366e-49	182.0	COG1370@1|root,arCOG00991@2157|Archaea,41SP1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Patch-forming domain C2 of tRNA-guanine transglycosylase	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
SRR25158390_k127_345814_31	1459636.NTE_00450	1.006e-31	130.0	COG1813@1|root,arCOG01863@2157|Archaea	2157|Archaea	K	transcription factor, homolog of eukaryotic MBF1	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
SRR25158390_k127_345814_12	1459636.NTE_00449	6.818e-123	404.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158390_k127_345814_21	1459636.NTE_00448	2.741e-60	213.0	COG1303@1|root,arCOG01857@2157|Archaea,41SIR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	-	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
SRR25158390_k127_345814_1	1459636.NTE_03053	1.059e-284	885.0	COG0155@1|root,arCOG02055@2157|Archaea,41S5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Sulfite reductase	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158390_k127_345814_11	1459636.NTE_03054	1.567e-123	403.0	COG2897@1|root,arCOG02019@2157|Archaea,41SBN@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158390_k127_3476229_0	234267.Acid_1081	4.033e-85	289.0	COG2326@1|root,COG2326@2|Bacteria,3Y44F@57723|Acidobacteria	57723|Acidobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158390_k127_3476229_5	63737.Npun_R0269	3.017e-05	46.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	CHRD,DUF839,HemolysinCabind,Phytase-like
SRR25158390_k127_3476229_6	1123392.AQWL01000005_gene3194	0.0003026	49.0	COG4222@1|root,COG4222@2|Bacteria,1QWRR@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
SRR25158390_k127_3476229_1	247490.KSU1_C1274	4.178e-31	136.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_3476229_4	1173020.Cha6605_3186	5.39e-11	71.0	28N7T@1|root,2ZBCE@2|Bacteria,1G50K@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3476229_2	1459636.NTE_00049	8.646e-30	123.0	COG2062@1|root,arCOG01992@2157|Archaea	2157|Archaea	T	TIGRFAM phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158390_k127_3488459_20	1229909.NSED_06675	1.507e-05	49.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3488459_15	686340.Metal_2216	5.08e-19	94.0	2C5IF@1|root,2Z9B7@2|Bacteria,1R5AB@1224|Proteobacteria,1SJEE@1236|Gammaproteobacteria,1XGBF@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1264
SRR25158390_k127_3488459_7	1459636.NTE_03520	2.08e-52	195.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3488459_12	1459636.NTE_03027	5.22e-27	118.0	arCOG08805@1|root,arCOG08805@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3488459_3	1048834.TC41_0139	1.382e-72	264.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158390_k127_3488459_13	1162668.LFE_1240	2.103e-25	112.0	COG1765@1|root,COG1765@2|Bacteria	1162668.LFE_1240|-	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3488459_22	582899.Hden_1460	0.0005067	45.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	MA20_34510	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
SRR25158390_k127_3488459_1	635013.TherJR_1270	9.866e-106	360.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2606T@186807|Peptococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	noxE	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158390_k127_3488459_17	574376.BAMA_00935	6.886e-14	79.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_3488459_14	1459636.NTE_00881	1.885e-20	97.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3488459_10	1459636.NTE_00881	3.781e-33	133.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3488459_8	378806.STAUR_7823	2.74e-45	176.0	2EYGB@1|root,33RQ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3488459_2	523791.Kkor_0590	1.433e-73	260.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_3488459_6	1459636.NTE_02436	1.368e-57	218.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
SRR25158390_k127_3488459_18	1458357.BG58_27645	2.168e-11	71.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2VRA9@28216|Betaproteobacteria,1K6DX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
SRR25158390_k127_3488459_19	1041146.ATZB01000034_gene587	1.123e-06	60.0	COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,2TSRA@28211|Alphaproteobacteria,4B7PT@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	GXGXG motif	glxC	-	2.1.1.21	ko:K22082	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG
SRR25158390_k127_3488459_9	868131.MSWAN_1789	9.214e-42	164.0	COG0067@1|root,arCOG00095@2157|Archaea,2XUF6@28890|Euryarchaeota,23PBU@183925|Methanobacteria	183925|Methanobacteria	E	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GATase_7
SRR25158390_k127_3488459_21	670307.HYPDE_25073	0.0003742	52.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	glxD	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
SRR25158390_k127_3488459_4	565033.GACE_0276	3.692e-69	254.0	COG0069@1|root,COG1145@1|root,arCOG00619@2157|Archaea,arCOG02187@2157|Archaea,2Y7H6@28890|Euryarchaeota,245Q2@183980|Archaeoglobi	183980|Archaeoglobi	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_syn_central,Glu_synthase
SRR25158390_k127_3488459_0	1229909.NSED_09490	1.134e-152	497.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_3488459_5	1459636.NTE_02630	2.94e-66	228.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158390_k127_3488459_11	1459636.NTE_01553	3.538e-29	120.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3505552_1	1459636.NTE_01417	3.744e-75	256.0	COG0301@1|root,arCOG00038@2157|Archaea,41T1A@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
SRR25158390_k127_3505552_0	1459636.NTE_01059	0.0	1182.0	COG1201@1|root,arCOG00557@2157|Archaea,41S8P@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158390_k127_3531024_0	1459636.NTE_01491	2.068e-26	113.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3531024_1	1229909.NSED_08905	6.405e-11	64.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158390_k127_3565_16	247490.KSU1_D0999	7.913e-27	128.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_3565_19	319225.Plut_0367	1.761e-14	87.0	COG1572@1|root,COG2304@1|root,COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3210@1|root,COG3391@1|root,COG3898@1|root,COG4932@1|root,COG5276@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3898@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.65,3.4.21.10	ko:K01212,ko:K01317,ko:K12287,ko:K20276	ko00500,ko02024,map00500,map02024	-	R05624,R11311	RC03278	ko00000,ko00001,ko01000,ko01002,ko02044,ko04131	-	GH32	-	DUF4347,VCBS,VWA_2
SRR25158390_k127_3565_9	436308.Nmar_0119	9.597e-54	203.0	COG2244@1|root,arCOG02209@2157|Archaea,41T3C@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3565_10	521011.Mpal_0585	4.338e-52	192.0	COG2120@1|root,arCOG03460@2157|Archaea,2XU80@28890|Euryarchaeota,2NAKP@224756|Methanomicrobia	224756|Methanomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158390_k127_3565_11	1131266.ARWQ01000002_gene480	9.405e-50	183.0	COG0558@1|root,arCOG00670@2157|Archaea,41SJ7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
SRR25158390_k127_3565_12	1459636.NTE_01923	6.325e-46	168.0	COG4830@1|root,arCOG04305@2157|Archaea,41SNM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02976	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S26e
SRR25158390_k127_3565_4	1459636.NTE_01921	1.318e-144	465.0	COG0061@1|root,COG0640@1|root,arCOG00394@2157|Archaea,arCOG01348@2157|Archaea,41SEC@651137|Thaumarchaeota	651137|Thaumarchaeota	HK	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158390_k127_3565_0	1459636.NTE_01920	8.826e-248	775.0	COG0504@1|root,arCOG00063@2157|Archaea,41S7G@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158390_k127_3565_6	1459636.NTE_00160	1.299e-122	415.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158390_k127_3565_15	1459636.NTE_01350	7.295e-30	124.0	COG1439@1|root,arCOG00721@2157|Archaea,41SPQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PIN domain of ribonuclease	-	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
SRR25158390_k127_3565_8	1459636.NTE_01351	9.893e-79	271.0	COG0061@1|root,arCOG01348@2157|Archaea,41SHP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158390_k127_3565_18	439481.Aboo_0440	7.464e-20	103.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota,3F33E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpD
SRR25158390_k127_3565_7	1459636.NTE_01580	6.727e-109	363.0	COG1798@1|root,COG1849@1|root,arCOG01224@2157|Archaea,arCOG04161@2157|Archaea,41SC2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	diphthine synthase	-	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	DUF357,TP_methylase
SRR25158390_k127_3565_3	1459636.NTE_01581	1.446e-175	556.0	COG0624@1|root,arCOG01107@2157|Archaea,41SAX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	M20_dimer,Peptidase_M20
SRR25158390_k127_3565_5	1459636.NTE_01582	1.005e-127	414.0	COG0189@1|root,arCOG01589@2157|Archaea,41SE8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
SRR25158390_k127_3565_17	1459636.NTE_01583	1.017e-22	97.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41STK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158390_k127_3565_1	1459636.NTE_01584	5.295e-214	670.0	COG0119@1|root,arCOG02092@2157|Archaea,41S7Y@651137|Thaumarchaeota	651137|Thaumarchaeota	E	HMGL-like	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158390_k127_3565_13	1229909.NSED_07170	1.707e-39	151.0	COG1522@1|root,arCOG01580@2157|Archaea,41SNE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158390_k127_3565_2	1459636.NTE_00736	7.228e-189	596.0	COG4992@1|root,arCOG00914@2157|Archaea,41SC8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158390_k127_3565_14	1459636.NTE_00735	2.152e-38	145.0	COG0548@1|root,arCOG00862@2157|Archaea,41SFB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis)	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158390_k127_3572873_0	1459636.NTE_03298	2.297e-17	83.0	arCOG08024@1|root,arCOG08024@2157|Archaea,41SRU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158390_k127_3572873_2	273057.SSO1362	6.475e-09	63.0	COG3335@1|root,arCOG02130@2157|Archaea	2157|Archaea	L	Transposase and inactivated derivatives	-	-	-	ko:K07494,ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_32,HTH_33
SRR25158390_k127_3572873_1	1114856.C496_15637	1.939e-09	64.0	COG3335@1|root,arCOG02129@2157|Archaea,2XVXE@28890|Euryarchaeota,23V2S@183963|Halobacteria	183963|Halobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_33
SRR25158390_k127_3602823_6	1131266.ARWQ01000002_gene514	6.421e-43	158.0	COG2086@1|root,arCOG00446@2157|Archaea,41SX2@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158390_k127_3602823_11	926562.Oweho_1108	4.276e-12	71.0	COG4095@1|root,COG4095@2|Bacteria,4NUQW@976|Bacteroidetes,1I54S@117743|Flavobacteriia	976|Bacteroidetes	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
SRR25158390_k127_3602823_10	1293047.CBMA010000051_gene3158	1.965e-12	68.0	arCOG11507@1|root,arCOG11507@2157|Archaea,2XXTV@28890|Euryarchaeota,23WCS@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3602823_1	1459636.NTE_02629	8.164e-194	617.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	2157|Archaea	E	TIGRFAM glutamine synthetase, type I	glnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_3602823_2	880073.Calab_3022	4.029e-143	468.0	COG1012@1|root,COG1012@2|Bacteria,2NQRG@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	gabD1	GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.gabD,iECUMN_1333.ECUMN_1793,iJN678.gabD	Aldedh
SRR25158390_k127_3602823_0	1459636.NTE_02605	0.0	1172.0	COG0464@1|root,arCOG01308@2157|Archaea,41SX8@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158390_k127_3602823_4	1459636.NTE_00092	2.745e-84	290.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	1459636.NTE_00092|-	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_3602823_9	1569209.BBPH01000009_gene1527	2.614e-18	91.0	COG2323@1|root,COG2323@2|Bacteria,1MW5I@1224|Proteobacteria,2UE0I@28211|Alphaproteobacteria,2PWTT@265|Paracoccus	28211|Alphaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158390_k127_3602823_8	1459636.NTE_00054	6.137e-33	132.0	COG0328@1|root,arCOG02942@2157|Archaea	2157|Archaea	L	Ribonuclease	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158390_k127_3602823_3	1459636.NTE_01927	8.47e-117	394.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158390_k127_3602823_5	1459636.NTE_01493	2.157e-59	220.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_3602823_7	880072.Desac_2725	3.941e-33	133.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2WNTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ferritin Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158390_k127_3603917_4	1459636.NTE_02326	1.988e-115	376.0	COG0065@1|root,arCOG01698@2157|Archaea,41SYT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, large subunit	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158390_k127_3603917_3	1459636.NTE_02325	1.482e-115	374.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158390_k127_3603917_2	1131266.ARWQ01000001_gene1220	1.315e-152	496.0	COG0476@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG01676@2157|Archaea,41S5X@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS
SRR25158390_k127_3603917_0	1459636.NTE_00076	2.268e-205	644.0	COG0498@1|root,arCOG01434@2157|Archaea,41SEI@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_3603917_6	1459636.NTE_00075	8.602e-51	181.0	COG0139@1|root,arCOG02676@2157|Archaea,41SPE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158390_k127_3603917_1	1459636.NTE_00071	3.337e-154	499.0	COG1571@1|root,arCOG01115@2157|Archaea,41S9G@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	-	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743
SRR25158390_k127_3603917_5	1459636.NTE_00015	8.912e-79	268.0	COG1976@1|root,arCOG04176@2157|Archaea,41SIP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
SRR25158390_k127_3606804_0	1459636.NTE_00341	3.842e-89	302.0	COG2801@1|root,arCOG02125@2157|Archaea	2157|Archaea	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,rve
SRR25158390_k127_3606804_3	1122138.AQUZ01000019_gene8188	2.118e-14	80.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158390_k127_3606804_4	1227500.C494_15163	2.702e-06	50.0	COG3039@1|root,arCOG02751@2157|Archaea,2XUAF@28890|Euryarchaeota,23UD8@183963|Halobacteria	183963|Halobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_3606804_1	693661.Arcve_1601	1.005e-66	241.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158390_k127_3606804_2	1041930.Mtc_0621	1.885e-49	185.0	arCOG02754@1|root,arCOG10890@1|root,arCOG02754@2157|Archaea,arCOG10890@2157|Archaea,2Y0JM@28890|Euryarchaeota	28890|Euryarchaeota	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_3640766_15	671065.MetMK1DRAFT_00004870	2.65e-16	84.0	COG3189@1|root,arCOG06027@2157|Archaea,2XS3W@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158390_k127_3640766_17	314265.R2601_04638	1.115e-10	72.0	COG2273@1|root,COG2931@1|root,COG2273@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM60,HemolysinCabind,Metallophos,PPC,Peptidase_M10_C
SRR25158390_k127_3640766_1	1459636.NTE_01102	4.806e-142	462.0	COG0577@1|root,arCOG02312@2157|Archaea,41T94@651137|Thaumarchaeota	2157|Archaea	V	ABC-type transport system, involved in lipoprotein release, permease component	abcS-2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158390_k127_3640766_8	1459636.NTE_01103	1.302e-88	318.0	COG1361@1|root,arCOG02080@2157|Archaea,41T6N@651137|Thaumarchaeota	651137|Thaumarchaeota	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3640766_5	1459636.NTE_01104	3.944e-93	311.0	COG1136@1|root,arCOG00922@2157|Archaea,41T2R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
SRR25158390_k127_3640766_13	391616.OA238_c12030	3.004e-17	89.0	COG2931@1|root,COG2931@2|Bacteria,1N161@1224|Proteobacteria,2UDXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	type I secretion target repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158390_k127_3640766_20	1220534.B655_2232	0.0001219	51.0	COG0589@1|root,arCOG02053@2157|Archaea,2XXRS@28890|Euryarchaeota	28890|Euryarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_3640766_4	1459636.NTE_02645	1.103e-106	355.0	COG1533@1|root,arCOG01290@2157|Archaea	2157|Archaea	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158390_k127_3640766_19	313624.NSP_15790	1.985e-05	54.0	COG0515@1|root,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1HRF9@1161|Nostocales	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like_2,Peripla_BP_6,Pkinase
SRR25158390_k127_3640766_9	556261.HMPREF0240_02111	5.555e-65	230.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24B66@186801|Clostridia,36W4B@31979|Clostridiaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158390_k127_3640766_2	1459636.NTE_02504	5.045e-110	375.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_3640766_16	436308.Nmar_1647	5.009e-12	77.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41T0K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3640766_3	525904.Tter_0425	6.94e-109	362.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158390_k127_3640766_6	1459636.NTE_00092	7.882e-93	314.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	1459636.NTE_00092|-	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_3640766_12	1459636.NTE_00408	8.567e-21	94.0	arCOG08700@1|root,arCOG08700@2157|Archaea,41SV2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3640766_7	1459636.NTE_01409	3.948e-92	312.0	COG3276@1|root,arCOG01564@2157|Archaea,41SCR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	elongation factor Tu	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
SRR25158390_k127_3640766_0	693661.Arcve_0993	1.453e-235	757.0	COG0383@1|root,arCOG03661@2157|Archaea,2XVNX@28890|Euryarchaeota	28890|Euryarchaeota	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158390_k127_3640766_10	693661.Arcve_0994	3.643e-48	183.0	COG3769@1|root,arCOG01215@2157|Archaea,2XZBT@28890|Euryarchaeota	28890|Euryarchaeota	S	Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG)	mngB	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158390_k127_3640766_18	1459636.NTE_02995	2.583e-08	63.0	COG0582@1|root,arCOG01245@2157|Archaea,41T6H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158390_k127_3640766_14	1459636.NTE_02995	7.879e-17	86.0	COG0582@1|root,arCOG01245@2157|Archaea,41T6H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158390_k127_3643572_0	110319.CF8_0881	7.667e-27	117.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4DS73@85009|Propionibacteriales	201174|Actinobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158390_k127_3644032_14	1459636.NTE_03312	3.753e-13	70.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	aknG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158390_k127_3644032_13	1459636.NTE_03311	2.938e-36	138.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3644032_8	1459636.NTE_03310	4.497e-63	216.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_3644032_12	1459636.NTE_03303	6.868e-37	146.0	COG1936@1|root,arCOG01038@2157|Archaea,41SPH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
SRR25158390_k127_3644032_9	1459636.NTE_03306	6.181e-58	205.0	COG1958@1|root,arCOG00999@2157|Archaea	2157|Archaea	K	PFAM Like-Sm ribonucleoprotein, core	-	-	-	-	-	-	-	-	-	-	-	-	LSM,Lsm_C,SM-ATX
SRR25158390_k127_3644032_2	1459636.NTE_03307	2.942e-198	631.0	COG0343@1|root,arCOG00989@2157|Archaea,41SF4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	-	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158390_k127_3644032_7	1459636.NTE_02327	1.031e-69	242.0	COG0066@1|root,arCOG02230@2157|Archaea,41T1U@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158390_k127_3644032_0	1459636.NTE_02326	1.674e-236	739.0	COG0065@1|root,arCOG01698@2157|Archaea,41SYT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, large subunit	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158390_k127_3644032_5	1459636.NTE_02325	3.926e-112	364.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158390_k127_3644032_4	1131266.ARWQ01000001_gene1220	5.193e-155	501.0	COG0476@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG01676@2157|Archaea,41S5X@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS
SRR25158390_k127_3644032_1	1459636.NTE_00076	6.557e-203	637.0	COG0498@1|root,arCOG01434@2157|Archaea,41SEI@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_3644032_10	1459636.NTE_00075	2.28e-51	184.0	COG0139@1|root,arCOG02676@2157|Archaea,41SPE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158390_k127_3644032_3	1459636.NTE_00071	2.345e-155	502.0	COG1571@1|root,arCOG01115@2157|Archaea,41S9G@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	-	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743
SRR25158390_k127_3644032_6	1459636.NTE_00015	7.171e-80	271.0	COG1976@1|root,arCOG04176@2157|Archaea,41SIP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
SRR25158390_k127_3644032_11	1459636.NTE_02001	5.355e-51	183.0	COG1131@1|root,arCOG00194@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158390_k127_3709630_0	1459636.NTE_00025	1.727e-97	328.0	arCOG07536@1|root,arCOG07536@2157|Archaea,41SZB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
SRR25158390_k127_3716383_0	1131266.ARWQ01000006_gene231	2.621e-97	332.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158390_k127_3716383_1	1041930.Mtc_1149	6.825e-81	282.0	COG0530@1|root,arCOG02881@2157|Archaea,2Y2BH@28890|Euryarchaeota,2NAGG@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158390_k127_375895_1	1459636.NTE_00890	1.132e-29	129.0	COG0517@1|root,arCOG00600@2157|Archaea	2157|Archaea	K	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_375895_3	1459636.NTE_00218	2.566e-24	107.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_00218|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_375895_2	1197130.BAFM01000013_gene2227	3.547e-28	120.0	arCOG08948@1|root,arCOG11838@1|root,arCOG08948@2157|Archaea,arCOG11838@2157|Archaea,2Y03W@28890|Euryarchaeota	28890|Euryarchaeota	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Ferritin_2
SRR25158390_k127_375895_0	335283.Neut_1712	2.084e-52	198.0	COG3391@1|root,COG3391@2|Bacteria,1R78P@1224|Proteobacteria,2VJ7I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3771332_2	1123239.KB898625_gene528	2.064e-06	51.0	COG3613@1|root,COG3613@2|Bacteria,1UI7D@1239|Firmicutes	1239|Firmicutes	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3771332_3	351160.RCIX2181	3.97e-06	49.0	arCOG06693@1|root,arCOG06693@2157|Archaea,2Y20U@28890|Euryarchaeota	28890|Euryarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3771332_0	1459636.NTE_01493	4.496e-56	210.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_3786786_3	1459636.NTE_02704	2.665e-11	64.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3786786_2	1459636.NTE_01263	1.11e-13	74.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_3786786_0	1459636.NTE_00550	1.098e-36	141.0	COG0655@1|root,COG2146@1|root,arCOG02578@2157|Archaea,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158390_k127_379813_0	1459636.NTE_01459	2.992e-88	302.0	COG0144@1|root,arCOG00973@2157|Archaea	2157|Archaea	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
SRR25158390_k127_379813_1	351160.LRC159	6.21e-21	99.0	COG1374@1|root,arCOG00993@2157|Archaea,2Y0D1@28890|Euryarchaeota	28890|Euryarchaeota	J	PUA domain	-	-	-	ko:K07565	-	-	-	-	ko00000,ko03009	-	-	-	UPF0113
SRR25158390_k127_3809430_2	1459636.NTE_01493	1.6e-10	64.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_3809430_4	1459636.NTE_00460	4.404e-06	50.0	arCOG07810@1|root,arCOG07810@2157|Archaea	2157|Archaea	S	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158390_k127_3809430_1	1459636.NTE_01494	3.459e-17	85.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01494|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3809430_3	1323361.JPOC01000017_gene2064	1.948e-06	51.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4G0TI@85025|Nocardiaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Lactonase
SRR25158390_k127_3809430_0	1459636.NTE_01927	1.063e-105	362.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158390_k127_3809430_6	390874.Tpet_0561	0.0001872	48.0	COG1597@1|root,COG1597@2|Bacteria,2GCWI@200918|Thermotogae	200918|Thermotogae	I	diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158390_k127_3837061_1	1047013.AQSP01000097_gene1959	2.28e-28	126.0	COG1597@1|root,COG1597@2|Bacteria,2NPQE@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158390_k127_3923328_1	1459636.NTE_01391	1.526e-107	356.0	COG1234@1|root,arCOG00501@2157|Archaea,41SF7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158390_k127_3923328_2	1459636.NTE_01392	1.671e-83	286.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
SRR25158390_k127_3923328_0	1459636.NTE_02380	1.666e-281	880.0	COG0145@1|root,arCOG01511@2157|Archaea,41SZ7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158390_k127_3923328_3	1459636.NTE_00401	1.686e-82	281.0	COG1794@1|root,arCOG02005@2157|Archaea,41SM4@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158390_k127_3929247_0	396588.Tgr7_2351	1.416e-18	93.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_12,Methyltransf_2,Methyltransf_23
SRR25158390_k127_3937733_5	1094980.Mpsy_2342	2.567e-29	133.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	gvpD	-	-	-	-	-	-	-	-	-	-	-	GvpD
SRR25158390_k127_3937733_3	1229909.NSED_04685	5.579e-31	134.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_3937733_0	1459636.NTE_01403	1.88e-92	315.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
SRR25158390_k127_3937733_6	644281.MFS40622_1531	5.816e-14	78.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158390_k127_3937733_4	1459636.NTE_00894	1.422e-29	123.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Ribosomal_S30AE
SRR25158390_k127_3937733_2	1459636.NTE_03520	1.576e-57	210.0	COG3794@1|root,arCOG02926@2157|Archaea	1459636.NTE_03520|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3937733_7	1459636.NTE_01962	4.646e-09	61.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3937733_8	436308.Nmar_1669	0.0002327	51.0	arCOG08825@1|root,arCOG08825@2157|Archaea,41T1X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_3937733_1	1459636.NTE_00597	1.816e-62	220.0	COG3945@1|root,arCOG01471@2157|Archaea,41T45@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158390_k127_398806_6	1459636.NTE_01729	2.422e-39	152.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158390_k127_398806_0	1123368.AUIS01000008_gene2277	3.616e-98	329.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,2NCYJ@225057|Acidithiobacillales	1236|Gammaproteobacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158390_k127_398806_1	926549.KI421517_gene2554	1.925e-97	326.0	COG4294@1|root,COG4294@2|Bacteria,4NIZA@976|Bacteroidetes,47K7P@768503|Cytophagia	976|Bacteroidetes	L	UV-endonuclease UvdE	-	-	-	-	-	-	-	-	-	-	-	-	UvdE
SRR25158390_k127_398806_2	224325.AF_1000	4.324e-66	233.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158390_k127_398806_11	1121904.ARBP01000030_gene1982	4.384e-06	54.0	COG0745@1|root,COG0745@2|Bacteria	1121904.ARBP01000030_gene1982|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_398806_10	1279009.ADICEAN_00035	1.444e-11	67.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Malectin
SRR25158390_k127_398806_8	1459636.NTE_00902	1.791e-16	84.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR25158390_k127_398806_4	679926.Mpet_2032	2.985e-42	158.0	COG1742@1|root,arCOG07820@2157|Archaea,2XYGR@28890|Euryarchaeota,2NBC8@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Uncharacterised BCR, YnfA UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
SRR25158390_k127_398806_3	436308.Nmar_1681	2.632e-49	178.0	COG1742@1|root,arCOG07820@2157|Archaea,41TAS@651137|Thaumarchaeota	436308.Nmar_1681|-	S	Uncharacterised BCR, YnfA/UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	-
SRR25158390_k127_398806_7	483219.LILAB_32590	1.018e-26	123.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1MX4X@1224|Proteobacteria,43C05@68525|delta/epsilon subdivisions,2X7AX@28221|Deltaproteobacteria,2YWKH@29|Myxococcales	28221|Deltaproteobacteria	N	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRR25158390_k127_398806_9	1147.D082_31640	1.424e-12	74.0	COG2931@1|root,COG2931@2|Bacteria,1G8WY@1117|Cyanobacteria,1H63H@1142|Synechocystis	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	frpC	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158390_k127_398806_5	1229909.NSED_01010	2.637e-41	159.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158390_k127_3993377_1	1459636.NTE_01354	1.757e-83	285.0	COG1146@1|root,arCOG04548@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_3993377_0	1459636.NTE_00750	1.098e-120	395.0	COG0111@1|root,arCOG01754@2157|Archaea,41S8U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158390_k127_3993377_2	339670.Bamb_1613	7.088e-05	48.0	COG0251@1|root,COG0251@2|Bacteria,1MZIC@1224|Proteobacteria,2VZS7@28216|Betaproteobacteria,1K72J@119060|Burkholderiaceae	28216|Betaproteobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158390_k127_4031253_0	1502851.FG93_04527	1.199e-100	341.0	COG2706@1|root,COG2706@2|Bacteria,1MWGS@1224|Proteobacteria,2VETU@28211|Alphaproteobacteria,3JRRP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
SRR25158390_k127_4031253_1	1232410.KI421418_gene2313	1.079e-68	248.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NK7@68525|delta/epsilon subdivisions,2WKTV@28221|Deltaproteobacteria,43RYC@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158390_k127_4031253_3	1459636.NTE_01439	2.409e-12	68.0	COG0642@1|root,arCOG02362@1|root,arCOG02358@2157|Archaea,arCOG02362@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_4070275_1	1459636.NTE_01756	7.96e-164	524.0	COG0172@1|root,arCOG00403@2157|Archaea,41SC9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158390_k127_4070275_4	1459636.NTE_01754	1.879e-85	300.0	COG0608@1|root,arCOG00427@2157|Archaea,41SZF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
SRR25158390_k127_4070275_6	1459636.NTE_01753	1.418e-62	218.0	COG0184@1|root,arCOG04185@2157|Archaea,41SKP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
SRR25158390_k127_4070275_8	1459636.NTE_01751	1.05e-39	149.0	arCOG08672@1|root,arCOG08672@2157|Archaea,41SU2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4070275_5	1459636.NTE_01090	1.855e-72	249.0	arCOG08675@1|root,arCOG08675@2157|Archaea,41SI5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Monooxygenase subunit B protein	-	-	-	ko:K10945	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	Monooxygenase_B
SRR25158390_k127_4070275_7	1459636.NTE_00962	1.067e-42	158.0	arCOG10586@1|root,arCOG10586@2157|Archaea,41STH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4070275_2	1459636.NTE_00961	2.328e-130	417.0	arCOG08676@1|root,arCOG08676@2157|Archaea,41SCF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Archaeal ammonia monooxygenase subunit A (AmoA)	-	-	1.14.18.3,1.14.99.39	ko:K10944	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Archaeal_AmoA
SRR25158390_k127_4070275_3	930945.SiRe_2457	1.093e-115	380.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158390_k127_4070275_0	1459636.NTE_01233	4.898e-243	767.0	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158390_k127_4084393_0	765420.OSCT_0924	9.001e-30	133.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF
SRR25158390_k127_4084393_1	1355374.JARU01000004_gene1364	2.98e-06	59.0	COG0476@1|root,COG0476@2|Bacteria,1R3WR@1224|Proteobacteria	1224|Proteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Prok-E2_A,Prok-JAB,ThiF
SRR25158390_k127_409863_0	1459636.NTE_01074	2.635e-12	73.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41SSF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4106441_1	272134.KB731324_gene2232	2.388e-05	49.0	COG3293@1|root,2ZJP3@2|Bacteria,1GQG4@1117|Cyanobacteria,1HI2R@1150|Oscillatoriales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR25158390_k127_4108720_1	1459636.NTE_02122	3.924e-22	98.0	COG1744@1|root,arCOG00257@2157|Archaea	2157|Archaea	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
SRR25158390_k127_4108720_0	1459636.NTE_01496	9.536e-165	537.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_4108720_2	269799.Gmet_0010	1.169e-12	72.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria,43TUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158390_k127_4115_0	1459636.NTE_01052	4.474e-106	360.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_4115_2	172045.KS04_21865	0.0003641	43.0	COG1145@1|root,32SB1@2|Bacteria,4NQ8P@976|Bacteroidetes,1I2EJ@117743|Flavobacteriia	976|Bacteroidetes	C	Domain of Unknown Function (DUF326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158390_k127_4115_1	1459636.NTE_02515	1.217e-24	109.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_4201092_0	1459636.NTE_02558	3.115e-18	83.0	COG0377@1|root,arCOG01554@2157|Archaea,41S6D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158390_k127_4213370_0	1459636.NTE_03035	9.831e-96	316.0	COG3276@1|root,arCOG01563@2157|Archaea,41S80@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Initiation factor	-	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,eIF2_C
SRR25158390_k127_4213370_1	1459636.NTE_03034	9.229e-43	159.0	COG2125@1|root,arCOG01946@2157|Archaea,41SPC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	-	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
SRR25158390_k127_4246589_3	1459636.NTE_00432	2.958e-105	355.0	COG0446@1|root,arCOG01064@2157|Archaea,41SZR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158390_k127_4246589_10	1459636.NTE_03214	4.954e-48	175.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4246589_0	1459636.NTE_03216	0.0	1139.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158390_k127_4246589_5	1459636.NTE_00856	9.163e-96	320.0	COG0720@1|root,arCOG02172@2157|Archaea,41SY8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158390_k127_4246589_8	1459636.NTE_00858	2.874e-68	240.0	COG0367@1|root,arCOG00071@2157|Archaea,41SIX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRR25158390_k127_4246589_2	1459636.NTE_02931	9.597e-179	570.0	COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158390_k127_4246589_6	1459636.NTE_03105	3.144e-91	309.0	COG2301@1|root,arCOG00760@2157|Archaea,41S6F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158390_k127_4246589_1	1459636.NTE_03106	8.63e-194	609.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158390_k127_4246589_11	1459636.NTE_01464	1.834e-34	140.0	COG1920@1|root,arCOG04472@2157|Archaea,41SPV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Guanylyl transferase CofC like	-	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158390_k127_4246589_4	1131266.ARWQ01000006_gene244	1.353e-96	325.0	COG0391@1|root,arCOG04395@2157|Archaea,41SCH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158390_k127_4246589_9	1459636.NTE_01462	1.096e-60	223.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41SS8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4246589_7	1459636.NTE_02188	5.565e-77	267.0	COG4742@1|root,arCOG04362@2157|Archaea,41SGE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158390_k127_4246589_15	1459636.NTE_03129	3.203e-13	74.0	COG0412@1|root,arCOG01659@2157|Archaea,41T1E@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Chlorophyllase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_4246589_14	1459636.NTE_03129	1.359e-15	78.0	COG0412@1|root,arCOG01659@2157|Archaea,41T1E@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Chlorophyllase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_4246589_12	1459636.NTE_03340	1.625e-33	131.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_4246589_13	1459636.NTE_02191	4.565e-24	108.0	COG1873@1|root,arCOG02155@2157|Archaea	2157|Archaea	S	PRC-barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158390_k127_4256995_4	941639.BCO26_2227	5.661e-06	52.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1V41H@1239|Firmicutes,4HH52@91061|Bacilli,1ZHKF@1386|Bacillus	91061|Bacilli	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
SRR25158390_k127_4256995_5	1246448.ANAZ01000002_gene3967	5.166e-05	50.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
SRR25158390_k127_4256995_0	1459636.NTE_01740	7.523e-62	216.0	COG1607@1|root,arCOG00773@2157|Archaea,41T2J@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_4256995_2	886882.PPSC2_c2409	5.586e-20	97.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli,26YMI@186822|Paenibacillaceae	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_4256995_1	1459636.NTE_00183	4.573e-60	222.0	COG0477@1|root,arCOG00130@2157|Archaea,arCOG00134@2157|Archaea	2157|Archaea	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
SRR25158390_k127_4256995_3	402777.KB235903_gene2073	7.191e-09	64.0	COG0515@1|root,COG5435@1|root,COG0515@2|Bacteria,COG5435@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H9KR@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_42590_0	1459636.NTE_03312	7.091e-98	327.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	aknG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158390_k127_42590_1	1459636.NTE_03311	6.659e-37	139.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4292616_1	247490.KSU1_D0999	0.0006611	48.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_4295072_0	262724.TT_C1879	1.404e-37	153.0	COG0433@1|root,COG0433@2|Bacteria,1WME2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4295072_1	1459636.NTE_02166	2.128e-25	110.0	arCOG11431@1|root,arCOG11431@2157|Archaea,41T8G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4295072_2	443144.GM21_2393	1.501e-23	111.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4305314_2	1459636.NTE_03243	2.006e-24	113.0	2C5D3@1|root,2N5BY@2157|Archaea,41TAU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4305314_7	186497.PF1893	9.884e-06	51.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZIX@28890|Euryarchaeota,244GR@183968|Thermococci	183968|Thermococci	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_4305314_4	1459636.NTE_02412	1.221e-14	76.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_4305314_8	1282887.AUJG01000003_gene525	0.0009906	45.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158390_k127_4305314_6	1459636.NTE_02123	4.847e-09	57.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158390_k127_4305314_1	258594.RPA4724	1.015e-25	115.0	COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,3JRPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158390_k127_4305314_0	755178.Cyan10605_0904	9.985e-55	196.0	COG3542@1|root,COG3542@2|Bacteria,1G6JR@1117|Cyanobacteria	1117|Cyanobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158390_k127_431027_0	1122138.AQUZ01000019_gene8188	1.243e-16	89.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158390_k127_431027_1	247490.KSU1_D0999	5.93e-16	91.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_4313930_0	1459636.NTE_00888	1.749e-23	106.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_4313930_2	485913.Krac_10063	1.167e-15	82.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158390_k127_4313930_6	449447.MAE_59770	0.0005322	47.0	COG2044@1|root,COG2044@2|Bacteria,1GQSP@1117|Cyanobacteria	1117|Cyanobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158390_k127_4313930_3	1459636.NTE_03491	1.563e-14	77.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_4313930_5	589865.DaAHT2_0874	0.0001028	47.0	COG0745@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_8,PAS_9,Response_reg,sCache_2
SRR25158390_k127_4313930_7	1459636.NTE_02333	0.0006191	46.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_02333|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4313930_4	1385518.N798_03750	4.403e-10	70.0	29Y40@1|root,30JX3@2|Bacteria,2HY3H@201174|Actinobacteria,4FJMV@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4313930_1	1459636.NTE_02077	2.826e-23	99.0	COG0426@1|root,arCOG00509@2157|Archaea	2157|Archaea	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158390_k127_4328079_0	1459636.NTE_00264	4.47e-139	450.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158390_k127_4328079_2	1459636.NTE_02123	1.322e-90	321.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
SRR25158390_k127_4328079_1	1459636.NTE_02717	1.441e-128	419.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_4334_3	1459636.NTE_00055	1.848e-50	183.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158390_k127_4334_0	1459636.NTE_00056	1.546e-76	264.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158390_k127_4334_2	1459636.NTE_00057	1.241e-51	186.0	COG0394@1|root,arCOG04425@2157|Archaea,41T49@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158390_k127_4334_1	1459636.NTE_00058	7.793e-75	258.0	COG0580@1|root,arCOG04431@2157|Archaea,41SJI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158390_k127_4334_4	589924.Ferp_1587	1.553e-06	52.0	arCOG10363@1|root,arCOG10363@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4339718_0	1459636.NTE_01496	5.896e-98	335.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_4343066_3	1459636.NTE_02584	1.638e-27	115.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158390_k127_4343066_1	1459636.NTE_00429	4.01e-38	149.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4343066_0	1459636.NTE_02637	9.162e-57	211.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158390_k127_4343066_2	1123226.KB899283_gene3220	3.467e-29	128.0	COG1587@1|root,COG1587@2|Bacteria,1V0K1@1239|Firmicutes,4HFWP@91061|Bacilli,26S5F@186822|Paenibacillaceae	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRR25158390_k127_4343066_4	1243664.CAVL020000057_gene3162	1.421e-11	71.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,1ZCRU@1386|Bacillus	91061|Bacilli	T	Transcriptional regulator	vanR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_4363396_0	1459636.NTE_00533	1.083e-15	85.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,HisKA,MEDS,PAS_4
SRR25158390_k127_4363396_1	1459636.NTE_00669	1.398e-14	84.0	COG3685@1|root,arCOG11147@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158390_k127_4428032_37	1459636.NTE_03007	8.907e-38	148.0	COG0494@1|root,arCOG01072@2157|Archaea,41STX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158390_k127_4428032_5	1229909.NSED_02815	1.886e-225	706.0	COG0043@1|root,arCOG01671@2157|Archaea,41S94@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158390_k127_4428032_35	1459636.NTE_03122	1.618e-51	185.0	COG5496@1|root,arCOG04331@2157|Archaea	2157|Archaea	S	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_4428032_1	1459636.NTE_03123	1.398e-278	865.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
SRR25158390_k127_4428032_24	1459636.NTE_00665	5.161e-80	274.0	COG0463@1|root,arCOG00894@2157|Archaea,41SAS@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158390_k127_4428032_20	1459636.NTE_01730	8.201e-104	355.0	arCOG04615@1|root,arCOG04615@2157|Archaea	2157|Archaea	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158390_k127_4428032_25	1459636.NTE_01932	4.676e-76	271.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158390_k127_4428032_60	1459636.NTE_00200	5.885e-06	53.0	arCOG08677@1|root,arCOG08677@2157|Archaea	1459636.NTE_00200|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_2	1459636.NTE_00680	3.667e-271	847.0	COG0441@1|root,arCOG00401@2157|Archaea,41S9K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
SRR25158390_k127_4428032_45	1459636.NTE_00679	1.667e-20	92.0	arCOG05330@1|root,arCOG05330@2157|Archaea,41SUC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_21	1128421.JAGA01000003_gene3109	2.861e-97	335.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158390_k127_4428032_29	589924.Ferp_2384	2.727e-62	224.0	COG1004@1|root,arCOG00253@2157|Archaea,2XTQY@28890|Euryarchaeota,246SR@183980|Archaeoglobi	183980|Archaeoglobi	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158390_k127_4428032_23	1459636.NTE_03124	2.106e-80	280.0	COG0524@1|root,arCOG00014@2157|Archaea	2157|Archaea	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB,Regulator_TrmB,TrmB
SRR25158390_k127_4428032_18	1459636.NTE_00119	1.624e-112	364.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	2157|Archaea	S	Ferritin-like domain	dps	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158390_k127_4428032_17	1459636.NTE_02404	1.163e-112	372.0	COG0608@1|root,arCOG00424@2157|Archaea,41SE2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
SRR25158390_k127_4428032_54	1459636.NTE_02729	1.312e-09	64.0	COG0347@1|root,arCOG02305@2157|Archaea,41TB5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158390_k127_4428032_12	1229909.NSED_09015	7.59e-158	523.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158390_k127_4428032_44	1459636.NTE_01532	3.454e-22	98.0	arCOG08750@1|root,arCOG08750@2157|Archaea	1459636.NTE_01532|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_27	1459636.NTE_02858	9.733e-70	243.0	COG0149@1|root,arCOG01087@2157|Archaea,41SHT@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158390_k127_4428032_9	1459636.NTE_02857	4.825e-205	642.0	COG1980@1|root,arCOG04180@2157|Archaea,41S67@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
SRR25158390_k127_4428032_10	1459636.NTE_00103	6.189e-181	589.0	COG0550@1|root,arCOG01527@2157|Archaea,41TBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	-
SRR25158390_k127_4428032_22	436308.Nmar_1633	2.09e-88	299.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158390_k127_4428032_53	644282.Deba_2044	1.711e-11	66.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,42NWA@68525|delta/epsilon subdivisions,2WK2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,HTH_11,Lactamase_B
SRR25158390_k127_4428032_26	1459636.NTE_03129	9.334e-74	259.0	COG0412@1|root,arCOG01659@2157|Archaea,41T1E@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Chlorophyllase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158390_k127_4428032_61	981085.XP_010096580.1	6.434e-06	55.0	COG1409@1|root,KOG1378@2759|Eukaryota,37SYW@33090|Viridiplantae,3G9V5@35493|Streptophyta,4JJU7@91835|fabids	35493|Streptophyta	G	Purple acid phosphatase	-	GO:0003674,GO:0003824,GO:0003993,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005768,GO:0005794,GO:0005802,GO:0006109,GO:0006605,GO:0006626,GO:0006793,GO:0006796,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0008104,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009536,GO:0009941,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017038,GO:0019222,GO:0030943,GO:0031410,GO:0031967,GO:0031975,GO:0031982,GO:0031984,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042578,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044429,GO:0044431,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045040,GO:0045184,GO:0046907,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0061024,GO:0065007,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0080090,GO:0090150,GO:0090151,GO:0097708,GO:0098791	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_C,Pur_ac_phosph_N
SRR25158390_k127_4428032_58	247490.KSU1_D0999	3.126e-06	53.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_4428032_52	1459636.NTE_01061	1.531e-11	74.0	arCOG10358@1|root,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_6	1459636.NTE_02742	1.835e-221	712.0	COG0672@1|root,arCOG04330@2157|Archaea,41T07@651137|Thaumarchaeota	651137|Thaumarchaeota	P	High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158390_k127_4428032_49	1459636.NTE_01064	2.306e-16	82.0	COG0640@1|root,arCOG03067@2157|Archaea,41T7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_7	1459636.NTE_00832	4.955e-212	685.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_11	1459636.NTE_01645	3.047e-158	505.0	COG1260@1|root,arCOG04213@2157|Archaea,41SEZ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158390_k127_4428032_19	1459636.NTE_02318	6.157e-105	346.0	COG1378@1|root,arCOG02038@2157|Archaea,41SFR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
SRR25158390_k127_4428032_0	1459636.NTE_00800	0.0	1294.0	COG0480@1|root,arCOG01559@2157|Archaea,41S9B@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158390_k127_4428032_14	1459636.NTE_01978	4.147e-139	452.0	COG3769@1|root,arCOG04158@2157|Archaea	2157|Archaea	S	Mannosyl-3-phosphoglycerate synthase	mngA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
SRR25158390_k127_4428032_39	1459636.NTE_00822	6.038e-36	147.0	arCOG08714@1|root,arCOG08714@2157|Archaea,41SPW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_32	1459636.NTE_00823	2.262e-55	197.0	COG1259@1|root,arCOG01759@2157|Archaea,41SQI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158390_k127_4428032_47	1459636.NTE_02851	4.97e-20	96.0	arCOG10597@1|root,arCOG10597@2157|Archaea	2157|Archaea	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_31	436308.Nmar_0257	5.909e-58	205.0	COG1695@1|root,arCOG00002@2157|Archaea,41SN8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158390_k127_4428032_15	1459636.NTE_01742	6.657e-121	394.0	COG2513@1|root,arCOG00581@2157|Archaea,41SEN@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158390_k127_4428032_13	1459636.NTE_02468	1.068e-148	484.0	COG0621@1|root,arCOG01358@2157|Archaea,41SB9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	MiaB-like tRNA modifying enzyme	-	-	2.8.4.5	ko:K15865	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158390_k127_4428032_50	1459636.NTE_02466	1.418e-13	72.0	arCOG11612@1|root,arCOG11612@2157|Archaea,41T8D@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_48	1459636.NTE_02463	7.781e-19	86.0	COG2167@1|root,arCOG04177@2157|Archaea,41SUT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
SRR25158390_k127_4428032_41	1459636.NTE_02464	1.97e-31	126.0	COG2097@1|root,arCOG04473@2157|Archaea,41STQ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	-	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
SRR25158390_k127_4428032_46	1459636.NTE_00426	2.889e-20	93.0	arCOG08809@1|root,arCOG08809@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_38	1459636.NTE_00425	4.458e-37	146.0	COG1711@1|root,arCOG00551@2157|Archaea,41SVQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
SRR25158390_k127_4428032_3	1459636.NTE_00424	5.002e-251	781.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158390_k127_4428032_43	1173263.Syn7502_01281	4.446e-25	106.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1H11A@1129|Synechococcus	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158390_k127_4428032_4	1459636.NTE_02856	3.767e-241	749.0	COG5256@1|root,arCOG01561@2157|Archaea,41SD2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158390_k127_4428032_33	1459636.NTE_02855	4.454e-55	193.0	COG0051@1|root,arCOG01758@2157|Archaea,41SQB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158390_k127_4428032_59	111780.Sta7437_2108	3.613e-06	56.0	COG0515@1|root,COG0515@2|Bacteria,1G0M9@1117|Cyanobacteria,3VI7U@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158390_k127_4428032_16	1229909.NSED_01900	3.171e-115	373.0	COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158390_k127_4428032_34	1459636.NTE_01388	1.308e-53	192.0	COG1717@1|root,arCOG00781@2157|Archaea,41SP5@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
SRR25158390_k127_4428032_30	1459636.NTE_01387	2.524e-60	211.0	COG2147@1|root,arCOG04089@2157|Archaea,41SVC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
SRR25158390_k127_4428032_28	1459636.NTE_01385	2.706e-64	229.0	COG1650@1|root,arCOG01616@2157|Archaea,41SM3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
SRR25158390_k127_4428032_36	1459636.NTE_02877	3.653e-39	150.0	arCOG08781@1|root,arCOG08781@2157|Archaea	1459636.NTE_02877|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4428032_8	1459636.NTE_03103	6.158e-211	671.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158390_k127_4433225_1	1459636.NTE_00487	3.894e-54	201.0	COG1475@1|root,arCOG11113@2157|Archaea	2157|Archaea	K	TIGRFAM ParB RepB Spo0J family partition protein	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158390_k127_4433225_2	436308.Nmar_1678	2.512e-48	188.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158390_k127_4433225_5	272624.lpg1130	1.864e-19	94.0	COG2114@1|root,COG2972@1|root,COG2114@2|Bacteria,COG2972@2|Bacteria,1RDES@1224|Proteobacteria,1S0RQ@1236|Gammaproteobacteria,1JGJC@118969|Legionellales	118969|Legionellales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158390_k127_4433225_3	1121121.KB894289_gene2575	1.783e-27	117.0	COG2133@1|root,COG2133@2|Bacteria,1VBUK@1239|Firmicutes,4HKNP@91061|Bacilli,26YMI@186822|Paenibacillaceae	91061|Bacilli	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_4433225_0	1459636.NTE_03411	9.318e-81	271.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_4433225_7	1230457.C476_00132	5.554e-07	51.0	COG3243@1|root,arCOG06234@1|root,arCOG06234@2157|Archaea,arCOG06344@2157|Archaea,2XSZS@28890|Euryarchaeota,23SX8@183963|Halobacteria	183963|Halobacteria	I	poly(R)-hydroxyalkanoic acid synthase subunit PhaC	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,HHH_5
SRR25158390_k127_4433225_4	237609.PSAKL28_01500	1.167e-21	102.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	lapA	-	-	ko:K12549,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Cadherin_3,Calx-beta,DUF4347,HemolysinCabind,VWA,VWA_2
SRR25158390_k127_4433465_0	565045.NOR51B_2611	1.723e-30	129.0	COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,1J5SB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	divalent heavy-metal cations transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158390_k127_4433465_2	443144.GM21_2393	2.405e-17	88.0	2E3IT@1|root,32YH8@2|Bacteria,1N8T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4434614_2	1459636.NTE_00961	2.42e-43	158.0	arCOG08676@1|root,arCOG08676@2157|Archaea,41SCF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Archaeal ammonia monooxygenase subunit A (AmoA)	-	-	1.14.18.3,1.14.99.39	ko:K10944	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Archaeal_AmoA
SRR25158390_k127_4434614_0	1459636.NTE_01234	1.475e-162	516.0	COG1013@1|root,arCOG01599@2157|Archaea,41SAB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158390_k127_4434614_1	1131266.ARWQ01000012_gene1611	1.857e-47	175.0	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158390_k127_4447662_2	1459636.NTE_00560	1.511e-30	125.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_4447662_0	1123073.KB899242_gene946	3.574e-176	586.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria,1X3QM@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA ligase	lig3	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158390_k127_4447662_1	986075.CathTA2_1346	2.533e-49	186.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli	91061|Bacilli	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158390_k127_45784_0	1121324.CLIT_2c02800	1.167e-47	179.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin-like,Lactonase,PKD,TIG
SRR25158390_k127_463061_3	797304.Natgr_1485	1.091e-05	48.0	arCOG03919@1|root,arCOG03919@2157|Archaea,2XUDK@28890|Euryarchaeota,23TJR@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRR25158390_k127_463061_1	1459636.NTE_00005	6.658e-11	69.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_463061_2	1459636.NTE_00006	5.927e-08	61.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_490098_0	247490.KSU1_D0999	9.975e-27	121.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_50755_0	1459636.NTE_03075	2.752e-60	211.0	2DZ95@1|root,2N5MX@2157|Archaea,41T90@651137|Thaumarchaeota	1459636.NTE_03075|-	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	-
SRR25158390_k127_51991_33	436308.Nmar_0978	4.765e-06	50.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
SRR25158390_k127_51991_35	877418.ATWV01000003_gene560	0.0002641	49.0	COG0745@1|root,COG0745@2|Bacteria,2J7CF@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158390_k127_51991_19	1229909.NSED_08345	2.788e-31	126.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158390_k127_51991_9	1459636.NTE_02626	4.998e-93	314.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_51991_5	1459636.NTE_01496	1.418e-139	465.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_51991_13	1459636.NTE_00871	8.106e-68	241.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158390_k127_51991_28	273116.14325504	1.106e-09	61.0	COG5466@1|root,arCOG05278@2157|Archaea,2Y5U3@28890|Euryarchaeota,242H8@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158390_k127_51991_22	1459636.NTE_02704	9.519e-29	115.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_51991_34	1051646.VITU9109_24860	5.136e-06	53.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XSE5@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158390_k127_51991_25	1198452.Jab_2c11280	6.223e-18	89.0	COG3631@1|root,COG3631@2|Bacteria,1RGEA@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158390_k127_51991_23	1459636.NTE_01297	6.067e-22	99.0	COG0011@1|root,arCOG04373@2157|Archaea,41T99@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
SRR25158390_k127_51991_20	436308.Nmar_1439	2.869e-31	127.0	COG0346@1|root,arCOG02706@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158390_k127_51991_24	1123511.KB905840_gene805	4.177e-18	89.0	COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4H7ZV@909932|Negativicutes	909932|Negativicutes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158390_k127_51991_4	1459636.NTE_01317	1.114e-157	507.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158390_k127_51991_11	517417.Cpar_1355	3.493e-73	262.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
SRR25158390_k127_51991_6	1459636.NTE_01612	1.114e-132	430.0	COG0258@1|root,arCOG04050@2157|Archaea,41SBU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
SRR25158390_k127_51991_1	1459636.NTE_01444	2.458e-217	687.0	COG1351@1|root,arCOG01884@2157|Archaea,41SF6@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158390_k127_51991_15	1459636.NTE_00070	1.456e-61	211.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158390_k127_51991_16	1459636.NTE_02337	1.42e-46	173.0	COG1430@1|root,arCOG03116@2157|Archaea,41SP3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158390_k127_51991_0	1459636.NTE_02371	1.208e-303	942.0	COG0365@1|root,arCOG01529@2157|Archaea,41S8Z@651137|Thaumarchaeota	651137|Thaumarchaeota	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158390_k127_51991_26	1459636.NTE_02412	5.094e-17	83.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_51991_14	1459636.NTE_01446	5.181e-67	239.0	arCOG04054@1|root,arCOG04054@2157|Archaea,41SIQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_51991_8	1459636.NTE_00067	4.742e-105	346.0	COG2241@1|root,arCOG00650@2157|Archaea,41SGN@651137|Thaumarchaeota	651137|Thaumarchaeota	H	TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit	-	-	2.1.1.289	ko:K03399	ko00860,ko01100,map00860,map01100	-	R05813,R07775	RC00003,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158390_k127_51991_10	1459636.NTE_00066	8.272e-80	273.0	COG2047@1|root,arCOG00348@2157|Archaea	2157|Archaea	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158390_k127_51991_17	1459636.NTE_00060	1.183e-45	170.0	arCOG01995@1|root,arCOG01995@2157|Archaea,41T3M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158390_k127_51991_3	1459636.NTE_00085	1.157e-171	553.0	COG1311@1|root,arCOG04455@2157|Archaea,41T0D@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B
SRR25158390_k127_51991_2	1459636.NTE_00084	1.739e-173	552.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
SRR25158390_k127_51991_27	1459636.NTE_00082	1.072e-12	77.0	arCOG08041@1|root,arCOG08041@2157|Archaea,41SRT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
SRR25158390_k127_51991_31	1459636.NTE_00081	1.831e-06	55.0	arCOG08806@1|root,arCOG08806@2157|Archaea,41SUU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_51991_7	1459636.NTE_00080	1.308e-107	353.0	COG1646@1|root,arCOG01085@2157|Archaea,41SH4@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
SRR25158390_k127_51991_12	1459636.NTE_00079	5.099e-69	239.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
SRR25158390_k127_520914_3	1094980.Mpsy_0997	2.88e-58	227.0	COG0683@1|root,arCOG01021@2157|Archaea,2Y6Q1@28890|Euryarchaeota,2NAW8@224756|Methanomicrobia	224756|Methanomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158390_k127_520914_4	933262.AXAM01000126_gene962	1.728e-45	186.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria,2MI6A@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158390_k127_520914_2	1459636.NTE_01492	4.965e-59	228.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_520914_6	1459636.NTE_01491	6.651e-21	96.0	COG0784@1|root,arCOG02391@2157|Archaea	1459636.NTE_01491|-	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_520914_0	1459636.NTE_00331	2.413e-110	369.0	COG0517@1|root,arCOG00607@2157|Archaea	2157|Archaea	M	Belongs to the peptidase M50B family	-	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR25158390_k127_520914_8	211165.AJLN01000085_gene1571	7.834e-07	58.0	COG0515@1|root,COG0515@2|Bacteria,1G0M9@1117|Cyanobacteria,1JJCN@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,PsbP
SRR25158390_k127_520914_1	1459636.NTE_00183	1.582e-61	227.0	COG0477@1|root,arCOG00130@2157|Archaea,arCOG00134@2157|Archaea	2157|Archaea	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
SRR25158390_k127_520914_7	713586.KB900536_gene328	3.279e-19	94.0	COG2133@1|root,COG2133@2|Bacteria,1QWB2@1224|Proteobacteria	1224|Proteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_520914_5	1459636.NTE_01740	2.363e-43	160.0	COG1607@1|root,arCOG00773@2157|Archaea,41T2J@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158390_k127_52269_3	926550.CLDAP_39260	1.121e-15	84.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_32
SRR25158390_k127_52269_4	1007103.AFHW01000158_gene3050	1.098e-11	72.0	COG3335@1|root,COG3335@2|Bacteria,1V41H@1239|Firmicutes,4HH52@91061|Bacilli,26WN7@186822|Paenibacillaceae	91061|Bacilli	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR25158390_k127_52269_0	1459636.NTE_02717	2.178e-65	236.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_52269_2	1459636.NTE_02155	6.654e-16	79.0	COG0642@1|root,arCOG02358@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_52269_1	44689.DDB0232283	4.896e-32	140.0	COG1112@1|root,KOG1803@2759|Eukaryota,3XC2W@554915|Amoebozoa	554915|Amoebozoa	A	R3H domain	-	-	3.6.4.12,3.6.4.13	ko:K19036	-	-	-	-	ko00000,ko01000,ko03009,ko03012	-	-	-	AAA_12,R3H,zf-AN1
SRR25158390_k127_523746_14	1158345.JNLL01000001_gene1012	3.354e-05	53.0	COG0589@1|root,COG0589@2|Bacteria,2G4D6@200783|Aquificae	200783|Aquificae	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158390_k127_523746_13	926569.ANT_13930	3.373e-06	51.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
SRR25158390_k127_523746_12	679926.Mpet_1264	1.994e-07	57.0	COG3039@1|root,arCOG02751@2157|Archaea,2XTDW@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158390_k127_523746_7	1298865.H978DRAFT_3635	3.901e-21	99.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria,467J8@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
SRR25158390_k127_523746_11	1288298.rosmuc_00524	1.741e-12	77.0	COG1403@1|root,COG1403@2|Bacteria,1NP19@1224|Proteobacteria	1224|Proteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_523746_0	1459636.NTE_02733	1.217e-239	763.0	COG1204@1|root,arCOG00553@2157|Archaea,41SAK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
SRR25158390_k127_523746_1	1459636.NTE_02732	2.517e-129	421.0	COG0472@1|root,arCOG03199@2157|Archaea,41S8B@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family	-	-	2.7.8.15	ko:K01001	ko00510,ko01100,map00510,map01100	M00055	R05969	RC00002	ko00000,ko00001,ko00002,ko01000,ko01003	-	-	-	Glycos_transf_4
SRR25158390_k127_523746_5	406327.Mevan_1380	1.132e-25	110.0	COG0622@1|root,arCOG01141@2157|Archaea,2XX8V@28890|Euryarchaeota,23QUK@183939|Methanococci	183939|Methanococci	S	TIGRFAM phosphodiesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158390_k127_523746_9	1459636.NTE_03491	1.276e-14	76.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_523746_8	436308.Nmar_1456	2.268e-15	81.0	arCOG08670@1|root,arCOG08728@1|root,arCOG08670@2157|Archaea,arCOG08728@2157|Archaea	436308.Nmar_1456|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_523746_3	365046.Rta_29530	5.548e-64	223.0	COG0454@1|root,COG0456@2|Bacteria,1RDVM@1224|Proteobacteria,2VYAK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158390_k127_523746_10	1459636.NTE_03491	2.515e-14	76.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
SRR25158390_k127_523746_4	1459636.NTE_01493	1.58e-54	205.0	COG0784@1|root,arCOG07810@1|root,arCOG02391@2157|Archaea,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158390_k127_523746_2	1459636.NTE_02862	1.789e-118	398.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158390_k127_525366_15	1459636.NTE_03209	1.617e-16	80.0	COG1096@1|root,arCOG00676@2157|Archaea,41SQA@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	-
SRR25158390_k127_525366_17	1046627.BZARG_2934	1.068e-10	75.0	COG3211@1|root,COG3291@1|root,COG3211@2|Bacteria,COG3291@2|Bacteria,4NMVW@976|Bacteroidetes,1I1JQ@117743|Flavobacteriia	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158390_k127_525366_10	203122.Sde_0034	2.079e-34	153.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1RBY7@1224|Proteobacteria,1SYWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Chondroitinase B	-	-	-	-	-	-	-	-	-	-	-	-	Chondroitinas_B,F5_F8_type_C
SRR25158390_k127_525366_8	1459636.NTE_00031	1.999e-44	165.0	COG0864@1|root,arCOG01008@2157|Archaea,41SQM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
SRR25158390_k127_525366_16	1158318.ATXC01000001_gene187	9.42e-15	82.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G3K2@200783|Aquificae	200783|Aquificae	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158390_k127_525366_9	748449.Halha_2244	1.03e-43	171.0	COG0458@1|root,COG0458@2|Bacteria,1UIGF@1239|Firmicutes,25EMV@186801|Clostridia	186801|Clostridia	EF	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
SRR25158390_k127_525366_2	1459636.NTE_02402	6.167e-87	304.0	COG1215@1|root,arCOG01389@2157|Archaea,41TAH@651137|Thaumarchaeota	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glycos_transf_2
SRR25158390_k127_525366_4	1459636.NTE_00033	5.518e-84	284.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158390_k127_525366_3	1459636.NTE_00034	4.747e-84	289.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158390_k127_525366_7	1459636.NTE_02430	1.317e-53	196.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158390_k127_525366_13	1459636.NTE_02864	2.563e-22	98.0	COG1996@1|root,arCOG04341@2157|Archaea,41SWH@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	-
SRR25158390_k127_525366_14	1459636.NTE_00660	3.047e-20	91.0	arCOG08687@1|root,arCOG08687@2157|Archaea,41SVF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_525366_11	1459636.NTE_02126	1.873e-29	119.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
SRR25158390_k127_525366_5	1459636.NTE_03018	6.222e-69	238.0	COG0221@1|root,arCOG01711@2157|Archaea,41T3F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158390_k127_525366_0	1459636.NTE_03020	7.153e-193	608.0	COG0464@1|root,arCOG01307@2157|Archaea,41SA4@651137|Thaumarchaeota	651137|Thaumarchaeota	D	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,MIT,Vps4_C
SRR25158390_k127_525366_1	1459636.NTE_01454	2.957e-139	454.0	COG1061@1|root,arCOG00874@2157|Archaea,41SW0@651137|Thaumarchaeota	2157|Archaea	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158390_k127_525366_6	1459636.NTE_01455	2.353e-54	195.0	COG2042@1|root,arCOG04733@2157|Archaea,41SMC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ribosome biogenesis protein, C-terminal	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
SRR25158390_k127_525366_12	4533.OB07G21070.1	1.683e-28	124.0	KOG0909@1|root,KOG0909@2759|Eukaryota,37S7P@33090|Viridiplantae,3G906@35493|Streptophyta,3KP60@4447|Liliopsida,3IBAI@38820|Poales	35493|Streptophyta	O	Rad4 transglutaminase-like domain	PNG1	GO:0000224,GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006515,GO:0006516,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009636,GO:0009719,GO:0009725,GO:0009751,GO:0009987,GO:0010033,GO:0010035,GO:0010188,GO:0010193,GO:0014070,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030163,GO:0036211,GO:0042221,GO:0042493,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051603,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901700	3.5.1.52	ko:K01456	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000	-	-	-	Rad4,Transglut_core
SRR25158390_k127_5634_13	1459636.NTE_02636	4.26e-20	94.0	COG1525@1|root,arCOG03192@2157|Archaea,41T4A@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158390_k127_5634_10	1445613.JALM01000036_gene2864	8.069e-38	147.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DXUF@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0019725,GO:0030312,GO:0031406,GO:0036094,GO:0042592,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046983,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0055114,GO:0065007,GO:0065008,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_5634_16	1459636.NTE_02717	3.237e-08	57.0	COG2141@1|root,arCOG02410@2157|Archaea	2157|Archaea	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_5634_15	351160.RRC242	1.161e-12	73.0	COG2141@1|root,arCOG02410@2157|Archaea,2XUEF@28890|Euryarchaeota	28890|Euryarchaeota	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158390_k127_5634_12	1116369.KB890024_gene3250	8.517e-21	95.0	COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria,2U9XS@28211|Alphaproteobacteria,43PYA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158390_k127_5634_3	63737.Npun_F2216	1.709e-75	259.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria,1HQ1K@1161|Nostocales	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SRR25158390_k127_5634_1	644966.Tmar_1413	4.914e-85	293.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WCYS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158390_k127_5634_17	1121904.ARBP01000005_gene4462	2.535e-07	56.0	COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes	976|Bacteroidetes	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158390_k127_5634_11	485913.Krac_11126	3.488e-26	112.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158390_k127_5634_0	1379698.RBG1_1C00001G0911	6.006e-95	320.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	2.8.1.12,4.6.1.17	ko:K03635,ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	-	MOSC,MoCF_biosynth,MoaC
SRR25158390_k127_5634_9	859653.HIMB5_00003360	1.507e-41	162.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158390_k127_5634_6	403833.Pmob_0375	4.84e-57	215.0	COG0303@1|root,COG0303@2|Bacteria,2GCCX@200918|Thermotogae	200918|Thermotogae	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158390_k127_5634_2	479434.Sthe_2181	1.724e-76	277.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158390_k127_5634_18	1121090.KB894688_gene1769	1.508e-05	53.0	COG4276@1|root,COG4276@2|Bacteria,1UAHV@1239|Firmicutes,4IKWC@91061|Bacilli,1ZJR4@1386|Bacillus	91061|Bacilli	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_5634_8	1459636.NTE_01496	9.633e-50	197.0	COG0642@1|root,arCOG03644@1|root,arCOG02358@2157|Archaea,arCOG03644@2157|Archaea,41T5G@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR25158390_k127_5634_7	1229909.NSED_02900	7.261e-53	190.0	COG0432@1|root,arCOG04214@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158390_k127_5634_14	1459636.NTE_00668	5.072e-14	72.0	COG1063@1|root,arCOG01459@2157|Archaea	2157|Archaea	C	Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a	fdh	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158390_k127_5634_4	1459636.NTE_01148	5.065e-73	249.0	COG1225@1|root,arCOG00310@2157|Archaea	2157|Archaea	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158390_k127_5634_5	1459636.NTE_01147	2.744e-63	222.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158390_k127_579322_7	1459636.NTE_00051	1.959e-35	137.0	COG0125@1|root,arCOG01891@2157|Archaea	2157|Archaea	F	thymidylate kinase	-	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158390_k127_579322_4	1459636.NTE_00052	1.108e-97	324.0	COG0125@1|root,arCOG01891@2157|Archaea	1459636.NTE_00052|-	F	thymidylate kinase	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158390_k127_579322_6	1459636.NTE_02269	4.638e-57	205.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158390_k127_579322_10	436308.Nmar_0009	2.343e-06	51.0	arCOG01806@1|root,arCOG01806@2157|Archaea,41T2B@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_579322_3	1459636.NTE_00045	5.606e-119	391.0	COG0573@1|root,arCOG00167@2157|Archaea,41SYE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_579322_5	42256.RradSPS_0703	3.05e-67	239.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_579322_1	1459636.NTE_00041	3.183e-124	409.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
SRR25158390_k127_579322_0	1459636.NTE_00046	2.855e-135	439.0	COG0226@1|root,arCOG08033@1|root,arCOG00213@2157|Archaea,arCOG08033@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158390_k127_579322_8	1459636.NTE_01512	2.845e-25	110.0	COG2236@1|root,arCOG00040@2157|Archaea,41TA1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosyltransferase	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_579322_2	1459636.NTE_00018	1.149e-122	400.0	COG0115@1|root,arCOG02297@2157|Archaea,41SD5@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158390_k127_579322_9	1459636.NTE_00019	1.755e-17	83.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158390_k127_600033_0	1459636.NTE_01100	1.837e-116	376.0	arCOG08699@1|root,arCOG08699@2157|Archaea,41S8N@651137|Thaumarchaeota	1459636.NTE_01100|-	C	PFAM Ammonia monooxygenase methane monooxygenase, subunit C	-	-	-	ko:K10946	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	-
SRR25158390_k127_600033_1	671143.DAMO_2372	1.676e-111	379.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_600033_2	485913.Krac_2322	5.875e-72	254.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158390_k127_669861_2	1459636.NTE_00755	5.225e-15	76.0	COG5486@1|root,arCOG10678@2157|Archaea	2157|Archaea	S	metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158390_k127_669861_0	1041930.Mtc_1620	4.45e-259	819.0	COG2217@1|root,COG3350@1|root,arCOG01576@2157|Archaea,arCOG04507@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158390_k127_669861_1	1459636.NTE_02515	6.076e-21	98.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_669861_3	1459636.NTE_01729	3.203e-07	51.0	COG1522@1|root,arCOG01585@2157|Archaea,41T4Z@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_AsnC-type
SRR25158390_k127_671544_0	1459636.NTE_02663	3.388e-168	537.0	COG2046@1|root,arCOG04191@2157|Archaea,41SER@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158390_k127_671544_1	1459636.NTE_02662	3.267e-110	362.0	COG0175@1|root,arCOG00124@2157|Archaea,41S9Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158390_k127_671544_2	1459636.NTE_02661	1.428e-105	359.0	COG1254@1|root,arCOG00643@2157|Archaea	2157|Archaea	C	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Acylphosphatase
SRR25158390_k127_671544_5	1131266.ARWQ01000004_gene1493	2.498e-85	290.0	COG0543@1|root,arCOG02199@2157|Archaea,41SY5@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SRR25158390_k127_671544_3	436308.Nmar_1390	8.42e-105	349.0	COG0167@1|root,arCOG00603@2157|Archaea	2157|Archaea	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R01868,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158390_k127_671544_6	1123288.SOV_5c03890	2.163e-75	261.0	COG1099@1|root,COG1099@2|Bacteria,1UZM4@1239|Firmicutes	1239|Firmicutes	S	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
SRR25158390_k127_671544_4	1123288.SOV_5c03880	7.089e-87	295.0	COG1082@1|root,COG1082@2|Bacteria,1TSIG@1239|Firmicutes	1239|Firmicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158390_k127_671544_9	1229909.NSED_08245	2.871e-45	167.0	arCOG08677@1|root,arCOG08677@2157|Archaea,41SVJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_671544_8	1459636.NTE_02860	1.321e-65	230.0	COG2860@1|root,arCOG04641@2157|Archaea,41SIS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158390_k127_671544_11	1459636.NTE_02416	5.391e-39	153.0	COG0671@1|root,arCOG03056@2157|Archaea	2157|Archaea	I	PFAM phosphoesterase, PA-phosphatase related	sepP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158390_k127_671544_10	269797.Mbar_A0810	3.333e-45	183.0	COG3291@1|root,COG3391@1|root,arCOG03991@1|root,arCOG02508@2157|Archaea,arCOG02562@2157|Archaea,arCOG03991@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158390_k127_671544_7	1459636.NTE_01398	2.446e-74	261.0	arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_671544_14	1459636.NTE_01667	2.044e-30	124.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_671544_19	1229909.NSED_08385	3.349e-06	51.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158390_k127_671544_13	1459636.NTE_03044	4.583e-34	135.0	arCOG08654@1|root,arCOG08654@2157|Archaea,41SRM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_671544_12	1459636.NTE_00971	1.003e-37	149.0	COG0500@1|root,arCOG01787@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31
SRR25158390_k127_671544_18	404380.Gbem_0338	2.786e-10	70.0	COG2133@1|root,COG2133@2|Bacteria,1PUU2@1224|Proteobacteria,433G4@68525|delta/epsilon subdivisions,2WXG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_671544_17	1229909.NSED_02135	2.403e-12	72.0	arCOG08665@1|root,arCOG08665@2157|Archaea	2157|Archaea	S	Haem utilisation ChuX/HutX	-	-	-	-	-	-	-	-	-	-	-	-	ChuX_HutX
SRR25158390_k127_671544_16	1459636.NTE_00089	6.644e-28	118.0	COG0109@1|root,arCOG03103@2157|Archaea	2157|Archaea	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158390_k127_671544_15	1459636.NTE_01553	2.686e-28	117.0	arCOG12283@1|root,arCOG12283@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_675723_17	1459636.NTE_01916	4.784e-20	92.0	COG0640@1|root,arCOG04056@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5,TrmB
SRR25158390_k127_675723_2	1459636.NTE_01915	2.806e-133	435.0	COG1474@1|root,arCOG00467@2157|Archaea,41SED@651137|Thaumarchaeota	2157|Archaea	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
SRR25158390_k127_675723_3	1459636.NTE_02299	1.444e-121	398.0	COG2835@1|root,arCOG01792@1|root,arCOG01792@2157|Archaea,arCOG04124@2157|Archaea,41T4S@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_675723_4	1459636.NTE_01313	1.856e-104	355.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_675723_9	436308.Nmar_1625	6.348e-57	207.0	COG1756@1|root,arCOG04122@2157|Archaea,41T2T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	-	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
SRR25158390_k127_675723_15	1459636.NTE_03109	1.108e-22	103.0	COG2023@1|root,arCOG04345@2157|Archaea,41STS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
SRR25158390_k127_675723_8	1459636.NTE_03108	2.017e-60	212.0	COG2238@1|root,arCOG01344@2157|Archaea,41SK1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	-	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
SRR25158390_k127_675723_13	1459636.NTE_03107	2.881e-33	130.0	COG2118@1|root,arCOG04179@2157|Archaea,41SR0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
SRR25158390_k127_675723_14	1459636.NTE_01466	4.188e-29	125.0	arCOG03727@1|root,arCOG03727@2157|Archaea,41STD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
SRR25158390_k127_675723_12	1459636.NTE_03120	5.003e-44	161.0	COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
SRR25158390_k127_675723_18	1131266.ARWQ01000009_gene960	1.956e-14	74.0	COG2051@1|root,arCOG04108@2157|Archaea,41SUD@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps27e	-	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
SRR25158390_k127_675723_19	877455.Metbo_0364	1.612e-12	76.0	COG2266@1|root,arCOG01871@2157|Archaea,2XZP4@28890|Euryarchaeota,23P5D@183925|Methanobacteria	183925|Methanobacteria	M	Cytidylyltransferase	cobY	-	2.7.7.62	ko:K19712	ko00860,ko01100,map00860,map01100	-	R05222	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158390_k127_675723_11	1229909.NSED_00595	6.478e-46	175.0	COG0368@1|root,arCOG04338@2157|Archaea,41SI6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158390_k127_675723_6	1459636.NTE_03116	2.281e-87	299.0	COG1270@1|root,arCOG04274@2157|Archaea,41S6I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
SRR25158390_k127_675723_7	1459636.NTE_03115	2.023e-85	291.0	COG1492@1|root,arCOG00105@2157|Archaea,41SG6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA
SRR25158390_k127_675723_5	1459636.NTE_03114	1.665e-89	308.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158390_k127_675723_0	1459636.NTE_03113	2.894e-177	560.0	COG0136@1|root,arCOG00494@2157|Archaea,41SFD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate-semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158390_k127_675723_1	1459636.NTE_03111	6.316e-148	472.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158390_k127_675723_16	1459636.NTE_00099	4.696e-20	90.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158390_k127_675723_10	1459636.NTE_01473	3.327e-48	180.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
SRR25158390_k127_767951_0	1459636.NTE_02421	1.017e-05	47.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_774013_0	1459636.NTE_02924	7.473e-91	310.0	COG1205@1|root,arCOG00555@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158390_k127_774013_1	1229909.NSED_09845	7.265e-83	282.0	COG0300@1|root,arCOG01263@2157|Archaea,41SXQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158390_k127_774013_2	1459636.NTE_01042	7.685e-37	146.0	arCOG08812@1|root,arCOG08812@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_774013_3	1459636.NTE_01719	1.816e-24	104.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T4V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158390_k127_78608_2	1459636.NTE_00104	2.283e-218	680.0	COG0183@1|root,arCOG01278@2157|Archaea,41SCI@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158390_k127_78608_21	1459636.NTE_00105	4.087e-41	154.0	COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota	651137|Thaumarchaeota	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158390_k127_78608_22	1459636.NTE_00108	3.511e-36	145.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
SRR25158390_k127_78608_4	436308.Nmar_1628	9.095e-190	616.0	COG0640@1|root,COG1328@1|root,arCOG00734@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota	651137|Thaumarchaeota	FK	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,HTH_20,NRDD
SRR25158390_k127_78608_0	1459636.NTE_00110	0.0	1397.0	COG0209@1|root,arCOG01917@1|root,arCOG03713@1|root,arCOG01917@2157|Archaea,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,41SAH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158390_k127_78608_6	1459636.NTE_00009	9.756e-151	481.0	COG0540@1|root,arCOG00911@2157|Archaea,41S6H@651137|Thaumarchaeota	651137|Thaumarchaeota	F	aspartate carbamoyltransferase	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158390_k127_78608_23	1459636.NTE_02378	4.131e-36	144.0	COG1818@1|root,arCOG00084@2157|Archaea,41SNW@651137|Thaumarchaeota	651137|Thaumarchaeota	S	THUMP domain	-	-	-	ko:K06963	-	-	-	-	ko00000,ko03016	-	-	-	THUMP
SRR25158390_k127_78608_20	1229909.NSED_07825	1.431e-43	166.0	COG0009@1|root,arCOG01952@2157|Archaea,41SPF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Sua5 YciO YrdC YwlC family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158390_k127_78608_13	1459636.NTE_02874	6.584e-102	340.0	COG2404@1|root,arCOG00423@2157|Archaea	2157|Archaea	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	-
SRR25158390_k127_78608_3	1459636.NTE_02879	2.151e-203	646.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
SRR25158390_k127_78608_1	1459636.NTE_02878	4.296e-236	741.0	COG1384@1|root,arCOG00485@2157|Archaea,41SB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158390_k127_78608_12	1459636.NTE_02880	2.299e-120	396.0	COG0150@1|root,arCOG00639@2157|Archaea,41SEE@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_78608_17	985053.VMUT_0432	1.77e-59	215.0	COG0171@1|root,arCOG00069@2157|Archaea,2XQ3J@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158390_k127_78608_11	1459636.NTE_01960	4.214e-125	405.0	COG1830@1|root,arCOG04044@2157|Archaea,41SCP@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158390_k127_78608_10	1459636.NTE_01959	1.327e-130	425.0	COG1465@1|root,arCOG04353@2157|Archaea,41S88@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
SRR25158390_k127_78608_8	1459636.NTE_01958	2.689e-148	473.0	COG0863@1|root,arCOG00115@2157|Archaea,41SZP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158390_k127_78608_18	1229909.NSED_02795	3.836e-56	204.0	COG0169@1|root,arCOG02097@2157|Archaea,41SKU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
SRR25158390_k127_78608_14	1459636.NTE_01954	5.801e-96	321.0	COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158390_k127_78608_15	1459636.NTE_01953	1.364e-84	288.0	COG1685@1|root,arCOG01025@2157|Archaea,41SGZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158390_k127_78608_9	1459636.NTE_01952	4.794e-141	460.0	COG0128@1|root,arCOG04134@2157|Archaea,41S5I@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158390_k127_78608_5	1459636.NTE_01951	4.033e-174	552.0	COG0082@1|root,arCOG04133@2157|Archaea,41SC3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158390_k127_78608_7	1459636.NTE_01950	2.384e-148	482.0	COG0436@1|root,COG1605@1|root,arCOG01130@2157|Archaea,arCOG02098@2157|Archaea,41SBV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Chorismate mutase type II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,CM_2
SRR25158390_k127_78608_19	1459636.NTE_01949	4.877e-51	192.0	COG0722@1|root,arCOG00245@2157|Archaea,41SM0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158390_k127_78608_25	1229909.NSED_07835	1.294e-12	74.0	COG1617@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG02197@2157|Archaea,41SSW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Kinase binding protein CGI-121	-	-	-	-	-	-	-	-	-	-	-	-	CGI-121,ThiS
SRR25158390_k127_78608_24	1459636.NTE_02377	1.394e-14	76.0	COG1617@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG02197@2157|Archaea,41SSW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Kinase binding protein CGI-121	-	-	-	-	-	-	-	-	-	-	-	-	CGI-121,ThiS
SRR25158390_k127_78608_26	178306.PAE0804	1.306e-11	68.0	COG1383@1|root,arCOG01885@2157|Archaea,2XRGM@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
SRR25158390_k127_78608_16	1459636.NTE_01764	1.637e-72	248.0	COG1676@1|root,arCOG01701@2157|Archaea,41SHW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
SRR25158390_k127_78608_27	1459636.NTE_01853	4.954e-10	60.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
SRR25158390_k127_792511_3	1459636.NTE_00041	6.814e-10	60.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	2157|Archaea	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
SRR25158390_k127_792511_1	266117.Rxyl_0820	4.333e-67	239.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_792511_0	1459636.NTE_00045	4.174e-123	403.0	COG0573@1|root,arCOG00167@2157|Archaea,41SYE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158390_k127_792511_2	1459636.NTE_03329	8.05e-56	201.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158390_k127_817443_2	1459636.NTE_02704	2.06e-22	97.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_817443_3	1229909.NSED_08545	8.228e-08	61.0	arCOG11548@1|root,arCOG11548@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_817443_1	330214.NIDE3819	6.168e-72	257.0	COG2843@1|root,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158390_k127_817443_0	1459636.NTE_00950	8.363e-180	568.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
SRR25158390_k127_817609_0	1459636.NTE_00766	1.438e-117	386.0	COG0598@1|root,arCOG02265@2157|Archaea,41SZC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158390_k127_817609_2	1459636.NTE_00603	1.146e-25	111.0	arCOG08747@1|root,arCOG08747@2157|Archaea,41T48@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_817609_1	1459636.NTE_03260	5.574e-83	290.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_817609_3	44251.PDUR_01110	3.779e-10	60.0	COG0596@1|root,COG0596@2|Bacteria,1USYC@1239|Firmicutes,4HBXD@91061|Bacilli,26VX0@186822|Paenibacillaceae	91061|Bacilli	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158390_k127_821475_0	713586.KB900536_gene328	1.177e-12	74.0	COG2133@1|root,COG2133@2|Bacteria,1QWB2@1224|Proteobacteria	1224|Proteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158390_k127_821475_1	1131266.ARWQ01000009_gene944	6.677e-07	52.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_821475_2	1203606.HMPREF1526_01905	0.0002564	48.0	COG3266@1|root,COG3266@2|Bacteria,1UNU7@1239|Firmicutes,24GSI@186801|Clostridia,36P7C@31979|Clostridiaceae	186801|Clostridia	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158390_k127_821962_16	1459636.NTE_02421	6.356e-09	57.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_821962_5	1459636.NTE_00888	1.135e-28	120.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
SRR25158390_k127_821962_10	247490.KSU1_D0999	8.933e-19	99.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_821962_18	218284.CCDN010000002_gene2595	3.596e-05	52.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158390_k127_821962_9	1173264.KI913949_gene3544	8.611e-24	105.0	COG4319@1|root,COG4319@2|Bacteria,1G6QY@1117|Cyanobacteria,1HBIC@1150|Oscillatoriales	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158390_k127_821962_13	443255.SCLAV_1862	7.145e-13	78.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
SRR25158390_k127_821962_8	247490.KSU1_D0999	3.245e-24	115.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_821962_1	1459636.NTE_03464	1.446e-86	301.0	COG1752@1|root,arCOG09020@2157|Archaea	2157|Archaea	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158390_k127_821962_4	1459636.NTE_01743	2.161e-38	147.0	COG0346@1|root,arCOG03101@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158390_k127_821962_12	591019.Shell_0124	1.62e-13	75.0	arCOG12413@1|root,arCOG12413@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_821962_6	247490.KSU1_C1274	5.36e-28	125.0	COG1409@1|root,COG3534@1|root,COG1409@2|Bacteria,COG3534@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158390_k127_821962_2	1459636.NTE_01932	1.516e-83	295.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158390_k127_821962_14	1123288.SOV_1c09900	2.425e-11	76.0	COG0726@1|root,COG0726@2|Bacteria,1UYYJ@1239|Firmicutes,4H3MV@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158390_k127_821962_0	1459636.NTE_02506	2.684e-116	387.0	arCOG01390@1|root,arCOG01390@2157|Archaea,41S7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158390_k127_821962_7	1459636.NTE_02850	1.168e-26	118.0	arCOG08794@1|root,arCOG08794@2157|Archaea,41SR7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_821962_3	1459636.NTE_02845	1.483e-39	153.0	COG3398@1|root,arCOG02611@2157|Archaea,41T7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158390_k127_821962_11	1459636.NTE_02846	4.328e-17	85.0	arCOG07573@1|root,arCOG07573@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_824185_0	1459636.NTE_03484	2.787e-118	385.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158390_k127_824185_1	1459636.NTE_02841	1.07e-52	199.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41T50@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_832198_0	373903.Hore_22980	1.774e-88	300.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,24G0B@186801|Clostridia	186801|Clostridia	P	-transport system	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_832198_1	373903.Hore_22990	1.525e-85	292.0	COG1175@1|root,COG1175@2|Bacteria,1V7U8@1239|Firmicutes,25MIU@186801|Clostridia,3WBQM@53433|Halanaerobiales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158390_k127_832198_2	1459636.NTE_01495	9.48e-80	270.0	COG1653@1|root,arCOG00151@2157|Archaea	2157|Archaea	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158390_k127_846415_4	436308.Nmar_1695	0.0001496	44.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158390_k127_846415_1	1459636.NTE_01088	1.75e-20	94.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_846415_0	1459636.NTE_01770	9.323e-27	116.0	COG0582@1|root,arCOG01245@2157|Archaea,41SVT@651137|Thaumarchaeota	1459636.NTE_01770|-	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_846415_3	1459636.NTE_01770	4.056e-13	73.0	COG0582@1|root,arCOG01245@2157|Archaea,41SVT@651137|Thaumarchaeota	1459636.NTE_01770|-	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_846415_2	1147.D082_15950	3.381e-19	99.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H69I@1142|Synechocystis	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158390_k127_853642_0	1459636.NTE_01051	1.845e-284	885.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S6N@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18593	ko00720,ko01120,map00720,map01120	-	R10758	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158390_k127_853642_12	1459636.NTE_01054	5.696e-60	219.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158390_k127_853642_3	1459636.NTE_03297	2.197e-134	440.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158390_k127_853642_8	1459636.NTE_00095	9.018e-80	269.0	COG1675@1|root,arCOG04270@2157|Archaea,41SJ8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
SRR25158390_k127_853642_11	1459636.NTE_03545	2.116e-64	227.0	COG1985@1|root,arCOG01484@2157|Archaea,41SK2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
SRR25158390_k127_853642_5	1459636.NTE_03546	1.258e-115	386.0	COG0402@1|root,arCOG00692@2157|Archaea,41S61@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158390_k127_853642_10	1459636.NTE_03547	7.241e-69	242.0	COG2429@1|root,arCOG04202@2157|Archaea,41SHK@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity	gch3	-	3.5.4.29	ko:K08096	ko00740,ko01100,map00740,map01100	-	R07306	RC01790	ko00000,ko00001,ko01000	-	-	-	GCH_III
SRR25158390_k127_853642_16	1459636.NTE_03548	2.274e-45	168.0	COG0054@1|root,arCOG01323@2157|Archaea,41SQ6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158390_k127_853642_7	1459636.NTE_03549	4.462e-86	292.0	COG0108@1|root,arCOG01320@2157|Archaea,41SFW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
SRR25158390_k127_853642_13	1459636.NTE_03551	5.107e-59	211.0	COG0307@1|root,arCOG04713@2157|Archaea,41SKQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	riboflavin synthase, alpha	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158390_k127_853642_1	1459636.NTE_02933	1.605e-245	765.0	COG1690@1|root,arCOG04246@2157|Archaea,41SE4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158390_k127_853642_21	1459636.NTE_02934	9.863e-33	131.0	arCOG05529@1|root,arCOG05529@2157|Archaea,41SSJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	dsDNA_bind
SRR25158390_k127_853642_9	1459636.NTE_02936	7.865e-74	249.0	COG0100@1|root,arCOG04240@2157|Archaea,41SII@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158390_k127_853642_20	374847.Kcr_0043	1.029e-35	149.0	COG0611@1|root,arCOG00638@2157|Archaea	2157|Archaea	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158390_k127_853642_4	1459636.NTE_02946	1.194e-127	422.0	COG1109@1|root,arCOG00767@2157|Archaea,41SC1@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158390_k127_853642_6	1459636.NTE_03347	1.037e-101	353.0	COG3372@1|root,arCOG04356@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
SRR25158390_k127_853642_24	436308.Nmar_0303	7.796e-09	57.0	COG0598@1|root,arCOG02265@2157|Archaea,41SZC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158390_k127_853642_14	1459636.NTE_00456	8.088e-49	182.0	arCOG03142@1|root,arCOG03142@2157|Archaea,41T78@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_853642_23	436308.Nmar_1598	3.56e-10	65.0	arCOG08790@1|root,arCOG08790@2157|Archaea,41SWN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_853642_2	1459636.NTE_02706	1.426e-182	581.0	COG0043@1|root,arCOG01671@2157|Archaea,41SEQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158390_k127_853642_25	643867.Ftrac_0495	0.0001966	51.0	COG2374@1|root,COG4447@1|root,COG4733@1|root,COG4886@1|root,COG2374@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
SRR25158390_k127_853642_19	1459636.NTE_02478	4.421e-36	139.0	COG0836@1|root,arCOG02427@2157|Archaea	2157|Archaea	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0229	MannoseP_isomer,NTP_transferase
SRR25158390_k127_876266_1	373994.Riv7116_0738	3.309e-47	173.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158390_k127_876266_0	1293047.CBMA010000010_gene450	1.272e-71	247.0	COG0778@1|root,arCOG00288@2157|Archaea,2XTDP@28890|Euryarchaeota,23STU@183963|Halobacteria	183963|Halobacteria	C	COG0778 Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158390_k127_88918_0	1459636.NTE_00136	2.552e-41	161.0	COG1938@1|root,arCOG00347@2157|Archaea,41SSA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
SRR25158390_k127_88918_1	1459636.NTE_03231	7.045e-28	113.0	arCOG08782@1|root,arCOG08782@2157|Archaea,41SVH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158390_k127_9029_1	316274.Haur_2846	5.415e-98	330.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158390_k127_9029_3	317936.Nos7107_1153	6.572e-60	215.0	COG1121@1|root,COG1121@2|Bacteria,1G1A6@1117|Cyanobacteria,1HKUZ@1161|Nostocales	1117|Cyanobacteria	P	PFAM ABC transporter	mntA	-	-	ko:K09820,ko:K11603	ko02010,ko02020,map02010,map02020	M00243,M00316	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.1	-	-	ABC_tran
SRR25158390_k127_9029_2	1131553.JIBI01000009_gene1208	1.156e-71	252.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2VK89@28216|Betaproteobacteria,372S3@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ABC 3 transport family	mntB	-	-	ko:K02075,ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158390_k127_9029_4	1459636.NTE_02897	2.313e-12	67.0	COG1475@1|root,arCOG11113@2157|Archaea,41SYF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
## 1737 queries scanned
## Total time (seconds): 6.921125650405884
## Rate: 250.97 q/s