## Mon Dec 15 02:21:29 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158397_bin.4.fa -m mmseqs --itype genome -o SRR25158397_bin.4 --output_dir /data/result/bins/wyx/egg/SRR25158397_bin.4 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158397_k127_100121_1	1173022.Cri9333_3496	1.389e-169	561.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158397_k127_100121_2	1187851.A33M_3026	1.892e-167	544.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3FE8W@34008|Rhodovulum	28211|Alphaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158397_k127_100121_4	1144275.COCOR_00985	7.749e-54	204.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2WKWM@28221|Deltaproteobacteria,2YU8T@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158397_k127_100121_0	204669.Acid345_3065	3.905e-196	627.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
SRR25158397_k127_100121_3	1123054.KB907711_gene361	7.861e-69	266.0	COG1404@1|root,COG3266@1|root,COG1404@2|Bacteria,COG3266@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria,1WXY7@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158397_k127_1009493_0	1248917.ANFX01000011_gene167	3.554e-45	186.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158397_k127_1009493_1	525904.Tter_1683	3.382e-38	164.0	COG0515@1|root,COG3103@1|root,COG0515@2|Bacteria,COG4991@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K07282,ko:K12132,ko:K15539	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,SH3_3,SH3_4
SRR25158397_k127_1009493_2	58344.JOEL01000022_gene988	3.226e-16	90.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRR25158397_k127_1009493_3	523791.Kkor_2538	8.111e-08	53.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XHG1@135619|Oceanospirillales	135619|Oceanospirillales	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRR25158397_k127_1014868_0	754035.Mesau_00885	1.69e-101	349.0	COG3210@1|root,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,2VFNT@28211|Alphaproteobacteria,43Q2V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1014868_3	754035.Mesau_00886	6.097e-65	226.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2U61A@28211|Alphaproteobacteria,43PGH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
SRR25158397_k127_1014868_2	754035.Mesau_00887	2.067e-65	227.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UB9G@28211|Alphaproteobacteria,43MIF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tail Collar domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
SRR25158397_k127_1014868_1	754035.Mesau_00888	1.538e-69	239.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2U8Y9@28211|Alphaproteobacteria,43PNV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
SRR25158397_k127_1014868_4	1547437.LL06_23285	3.66e-40	159.0	COG0454@1|root,COG0456@2|Bacteria,1N29T@1224|Proteobacteria,2UF3Q@28211|Alphaproteobacteria,43PNS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158397_k127_1014868_6	1396141.BATP01000054_gene2891	1.74e-16	86.0	2AX2R@1|root,31P12@2|Bacteria,46WJT@74201|Verrucomicrobia,2IWCE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Family of unknown function (DUF5329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5329
SRR25158397_k127_1014868_5	234267.Acid_7665	3.62e-29	123.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
SRR25158397_k127_1015962_0	204669.Acid345_4549	1.05e-285	917.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158397_k127_1015962_4	1408311.JNJM01000001_gene341	9.205e-15	87.0	COG0515@1|root,COG2304@1|root,COG0515@2|Bacteria,COG2304@2|Bacteria,1UPIH@1239|Firmicutes,25HH2@186801|Clostridia	186801|Clostridia	KLT	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
SRR25158397_k127_1015962_3	1382359.JIAL01000001_gene1619	3.767e-43	179.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
SRR25158397_k127_1015962_1	931276.Cspa_c40240	2.194e-49	188.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,36DJ0@31979|Clostridiaceae	186801|Clostridia	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158397_k127_1015962_2	234267.Acid_3115	8.958e-47	194.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria	57723|Acidobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
SRR25158397_k127_1015962_5	234267.Acid_3219	9.442e-12	73.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1036670_2	742722.HMPREF9463_00353	3.42e-16	86.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CUNU@84998|Coriobacteriia	84998|Coriobacteriia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158397_k127_1036670_1	426117.M446_5543	5.741e-201	650.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,1JSDB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158397_k127_1036670_0	378806.STAUR_7575	4.086e-241	754.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2Z3GS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158397_k127_10367_1	1353529.M899_0208	1.611e-82	297.0	COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2MUN1@213481|Bdellovibrionales,2WPS4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158397_k127_10367_6	639030.JHVA01000001_gene2022	2.759e-49	186.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_10367_0	234267.Acid_5590	4.514e-162	531.0	COG0843@1|root,COG0843@2|Bacteria,3Y2NS@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158397_k127_10367_4	481448.Minf_1950	8.117e-55	199.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158397_k127_10367_10	240016.ABIZ01000001_gene2011	3.731e-06	56.0	2DR0H@1|root,339NS@2|Bacteria,46ZIA@74201|Verrucomicrobia,2IUYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
SRR25158397_k127_10367_2	497964.CfE428DRAFT_2235	7.905e-68	239.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRR25158397_k127_10367_5	1156937.MFUM_1040009	5.845e-54	203.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158397_k127_10367_3	1267535.KB906767_gene1277	2.384e-67	244.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158397_k127_10367_8	497964.CfE428DRAFT_2238	1.442e-30	127.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158397_k127_10367_7	204669.Acid345_2222	9.853e-33	132.0	COG2322@1|root,COG2322@2|Bacteria,3Y4U9@57723|Acidobacteria,2JJKU@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SRR25158397_k127_10367_9	1442599.JAAN01000024_gene1876	5.26e-30	131.0	COG1051@1|root,COG1051@2|Bacteria,1NA5A@1224|Proteobacteria,1SFGB@1236|Gammaproteobacteria,1X6B0@135614|Xanthomonadales	135614|Xanthomonadales	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158397_k127_10367_12	794903.OPIT5_03375	0.0004827	44.0	COG0259@1|root,COG0259@2|Bacteria,46SRQ@74201|Verrucomicrobia,3K789@414999|Opitutae	414999|Opitutae	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158397_k127_1039822_2	1286106.MPL1_03960	2.393e-12	77.0	2EMIV@1|root,33F7F@2|Bacteria,1P8R6@1224|Proteobacteria,1SWDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1039822_1	215803.DB30_1661	2.209e-141	473.0	COG1132@1|root,COG1132@2|Bacteria,1NRJ2@1224|Proteobacteria,437FW@68525|delta/epsilon subdivisions,2X2NG@28221|Deltaproteobacteria,2YTZX@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
SRR25158397_k127_1039822_0	1254432.SCE1572_41910	3.155e-168	554.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1R2T0@1224|Proteobacteria,43BXM@68525|delta/epsilon subdivisions,2X78E@28221|Deltaproteobacteria,2YUMW@29|Myxococcales	28221|Deltaproteobacteria	V	Peptidase C39 family	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran,Peptidase_C39
SRR25158397_k127_1061203_23	1123278.KB893387_gene4430	9.218e-26	124.0	COG1577@1|root,COG1874@1|root,COG3391@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG3391@2|Bacteria,4PPRK@976|Bacteroidetes,47TYG@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1061203_17	1519464.HY22_03120	5.664e-43	177.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158397_k127_1061203_26	1118057.CAGX01000050_gene754	3.949e-15	80.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,22HFB@1570339|Peptoniphilaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_1061203_29	298655.KI912266_gene773	5.936e-08	60.0	COG4567@1|root,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158397_k127_1061203_21	290397.Adeh_3407	2.886e-29	118.0	COG4095@1|root,COG4095@2|Bacteria,1NFJU@1224|Proteobacteria,434KW@68525|delta/epsilon subdivisions,2WYYA@28221|Deltaproteobacteria,2YVSM@29|Myxococcales	28221|Deltaproteobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1061203_11	945713.IALB_1247	1.005e-54	202.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_1061203_2	395961.Cyan7425_1966	6.975e-183	582.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_1061203_0	395961.Cyan7425_1965	4.385e-215	676.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158397_k127_1061203_24	452637.Oter_1832	2.273e-22	114.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158397_k127_1061203_4	748247.AZKH_0082	1.301e-94	338.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158397_k127_1061203_18	1296990.H845_2208	1.64e-40	156.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2JS9R@204441|Rhodospirillales	204441|Rhodospirillales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158397_k127_1061203_3	682795.AciX8_1027	1.466e-130	425.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158397_k127_1061203_5	404380.Gbem_0959	6.815e-85	286.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158397_k127_1061203_12	1370125.AUWT01000024_gene5505	3.53e-53	191.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,238NX@1762|Mycobacteriaceae	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158397_k127_1061203_14	278963.ATWD01000001_gene1815	2.771e-48	176.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria,2JJAF@204432|Acidobacteriia	204432|Acidobacteriia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158397_k127_1061203_27	880072.Desac_1432	1.315e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158397_k127_1061203_20	439235.Dalk_1893	1.494e-33	132.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MKKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158397_k127_1061203_7	1144275.COCOR_03065	1.125e-77	268.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2YU2D@29|Myxococcales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158397_k127_1061203_8	591001.Acfer_1908	5.5e-68	237.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4H2UG@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158397_k127_1061203_1	1047013.AQSP01000074_gene1894	1.191e-194	618.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158397_k127_1061203_13	1336234.JAGN01000021_gene808	1.547e-49	180.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,27G53@186828|Carnobacteriaceae	91061|Bacilli	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158397_k127_1061203_28	1479239.JQMU01000001_gene579	1.647e-10	70.0	COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,2K6V8@204457|Sphingomonadales	204457|Sphingomonadales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158397_k127_1061203_10	644282.Deba_2921	4.191e-59	210.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158397_k127_1061203_19	234267.Acid_5102	1.007e-39	151.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria	57723|Acidobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158397_k127_1061203_9	378753.KRH_06300	4.512e-60	212.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,1W829@1268|Micrococcaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158397_k127_1061203_15	525903.Taci_1170	3.137e-45	168.0	COG0096@1|root,COG0096@2|Bacteria,3TAYB@508458|Synergistetes	508458|Synergistetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158397_k127_1061203_25	1379698.RBG1_1C00001G1583	1.296e-21	98.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158397_k127_1061203_6	204669.Acid345_1238	2.219e-79	268.0	COG0094@1|root,COG0094@2|Bacteria,3Y3PS@57723|Acidobacteria,2JHV4@204432|Acidobacteriia	204432|Acidobacteriia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158397_k127_1061203_22	526222.Desal_1196	9.502e-28	116.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MC5T@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158397_k127_1061203_16	240015.ACP_1441	2.516e-44	162.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158397_k127_1075048_1	445973.CLOBAR_02853	1.371e-46	175.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25RBZ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158397_k127_1075048_0	925775.XVE_2604	3.229e-66	235.0	COG2755@1|root,COG2755@2|Bacteria,1P3T8@1224|Proteobacteria,1T09G@1236|Gammaproteobacteria,1XCZI@135614|Xanthomonadales	135614|Xanthomonadales	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158397_k127_1075048_2	74547.PMT_0180	1.164e-10	64.0	COG1968@1|root,COG1968@2|Bacteria,1G0X2@1117|Cyanobacteria,1MMAQ@1212|Prochloraceae	1117|Cyanobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158397_k127_1093716_4	457429.ABJI02000053_gene2096	9.215e-75	255.0	COG2220@1|root,COG2220@2|Bacteria,2GNXJ@201174|Actinobacteria	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158397_k127_1093716_3	290397.Adeh_2107	1.302e-88	302.0	COG0500@1|root,COG2226@2|Bacteria,1R98E@1224|Proteobacteria,43847@68525|delta/epsilon subdivisions,2X3E4@28221|Deltaproteobacteria,2YVN5@29|Myxococcales	28221|Deltaproteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158397_k127_1093716_1	1121875.KB907556_gene591	1.806e-157	517.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase M20	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158397_k127_1093716_5	1174528.JH992898_gene2614	2.131e-65	255.0	COG4995@1|root,COG4995@2|Bacteria,1GDW4@1117|Cyanobacteria	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158397_k127_1093716_2	861299.J421_1733	3.532e-148	475.0	COG1131@1|root,COG1131@2|Bacteria,1ZUJT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_1093716_0	861299.J421_1732	0.0	1457.0	COG0308@1|root,COG0308@2|Bacteria,1ZSMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158397_k127_1093716_6	1278073.MYSTI_03632	3.137e-42	166.0	COG3409@1|root,COG3409@2|Bacteria,1RJYN@1224|Proteobacteria	1224|Proteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158397_k127_1099014_3	1121920.AUAU01000004_gene813	2.325e-85	293.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRR25158397_k127_1099014_0	385682.AFSL01000053_gene496	1.878e-127	419.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,2FN1B@200643|Bacteroidia,3XJVE@558415|Marinilabiliaceae	976|Bacteroidetes	E	Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_1099014_2	1267534.KB906755_gene4826	2.267e-109	380.0	COG1181@1|root,COG1181@2|Bacteria,3Y6Z0@57723|Acidobacteria,2JKPX@204432|Acidobacteriia	204432|Acidobacteriia	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158397_k127_1099014_1	1267533.KB906738_gene2098	1.615e-111	371.0	COG4307@1|root,COG4307@2|Bacteria,3Y69G@57723|Acidobacteria,2JM0B@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
SRR25158397_k127_1099014_4	716544.wcw_1110	4.557e-40	167.0	COG2947@1|root,COG2947@2|Bacteria,2JH2Z@204428|Chlamydiae	204428|Chlamydiae	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR25158397_k127_111443_2	1121015.N789_01640	8.492e-15	89.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X2Z4@135614|Xanthomonadales	135614|Xanthomonadales	T	phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
SRR25158397_k127_111443_1	204669.Acid345_0518	2.659e-36	150.0	COG3794@1|root,COG3794@2|Bacteria,3Y4UD@57723|Acidobacteria,2JJH0@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_111443_3	1449336.JQLO01000001_gene344	5.46e-08	55.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_111443_0	234267.Acid_5310	4.255e-42	158.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158397_k127_1128696_2	483219.LILAB_18790	2.884e-06	61.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K14475,ko:K20276	ko02024,ko05143,map02024,map05143	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,RCC1_2
SRR25158397_k127_1128696_1	1219049.SP5_072_00240	2.163e-06	59.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2K08H@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158397_k127_1128696_0	1121920.AUAU01000006_gene258	1.483e-101	345.0	COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria	57723|Acidobacteria	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158397_k127_1133856_5	102129.Lepto7375DRAFT_4516	1.615e-22	98.0	COG0606@1|root,COG0606@2|Bacteria,1G0K1@1117|Cyanobacteria,1H6YU@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158397_k127_1133856_7	640512.BC1003_5521	2.218e-08	63.0	298WQ@1|root,2ZW0P@2|Bacteria,1P7TW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1133856_0	1211114.ALIP01000006_gene929	4.297e-143	488.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X4SZ@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
SRR25158397_k127_1133856_6	1229203.KI301992_gene2312	4.264e-12	76.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_1133856_4	204669.Acid345_3984	4.936e-35	150.0	COG3240@1|root,COG3240@2|Bacteria,3Y6HW@57723|Acidobacteria,2JKSH@204432|Acidobacteriia	204432|Acidobacteriia	I	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
SRR25158397_k127_1133856_2	880073.Calab_1642	4.212e-61	227.0	COG2067@1|root,COG2067@2|Bacteria,2NPN1@2323|unclassified Bacteria	2|Bacteria	I	Membrane protein involved in aromatic hydrocarbon degradation	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
SRR25158397_k127_1133856_3	1123368.AUIS01000009_gene2452	1.927e-47	181.0	COG0739@1|root,COG0739@2|Bacteria,1RK0U@1224|Proteobacteria,1S6P9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158397_k127_1133856_1	940282.CADQ01000009_gene122	5.809e-141	472.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,2JPFI@204441|Rhodospirillales	204441|Rhodospirillales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158397_k127_1137925_0	377629.TERTU_1298	1.71e-182	584.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,1S3FZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_1137925_2	215803.DB30_5328	1.209e-32	137.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,431H7@68525|delta/epsilon subdivisions,2WWTH@28221|Deltaproteobacteria,2Z202@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158397_k127_1137925_3	1444309.JAQG01000004_gene3628	1.229e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,26S4H@186822|Paenibacillaceae	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_1137925_1	269799.Gmet_0987	2.559e-136	464.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,PAS_4
SRR25158397_k127_1139286_5	1366050.N234_22815	0.0001007	50.0	COG4568@1|root,COG4568@2|Bacteria,1NKDC@1224|Proteobacteria,2W48P@28216|Betaproteobacteria,1KEK0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	rho-dependent transcription termination	-	-	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158397_k127_1139286_0	290397.Adeh_2523	0.0	1122.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_1139286_3	671143.DAMO_1432	2.083e-46	173.0	COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria	2|Bacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_1139286_1	326297.Sama_0161	1.922e-186	600.0	COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,1RYUG@1236|Gammaproteobacteria,2Q9QW@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158397_k127_1139286_4	1279009.ADICEAN_01511	5.022e-15	87.0	COG3667@1|root,COG3667@2|Bacteria,4NICY@976|Bacteroidetes,47KK4@768503|Cytophagia	976|Bacteroidetes	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1139286_2	1192034.CAP_1695	9.896e-123	404.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_116461_5	448385.sce4867	1.74e-81	302.0	COG4124@1|root,COG4124@2|Bacteria,1QH7T@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_26
SRR25158397_k127_116461_0	1042376.AFPK01000038_gene582	1.718e-150	492.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HYXG@117743|Flavobacteriia	976|Bacteroidetes	GM	Glycosyl transferase family 21	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_hydro_26,Glyco_hydro_2_C,Glyco_transf_21
SRR25158397_k127_116461_17	715226.ABI_13330	0.0008382	51.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,Peptidase_C39_2,TPR_16,TPR_19,TPR_4,TPR_8
SRR25158397_k127_116461_16	1229487.AMYW01000039_gene883	0.0002596	52.0	COG3568@1|root,COG3568@2|Bacteria,4NIY0@976|Bacteroidetes,1I0C2@117743|Flavobacteriia,2NSNK@237|Flavobacterium	976|Bacteroidetes	S	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158397_k127_116461_9	587753.EY04_23705	1.406e-38	166.0	2C2AP@1|root,2ZAZ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_15	714943.Mucpa_0815	0.0002557	54.0	2EAJV@1|root,334NM@2|Bacteria,4P6NB@976|Bacteroidetes,1IZ6D@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_13	269796.Rru_A1376	1.055e-05	57.0	2DBKT@1|root,2Z9V9@2|Bacteria,1RCFS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_2	278963.ATWD01000001_gene2957	7.62e-91	309.0	COG0657@1|root,COG0657@2|Bacteria,3Y73T@57723|Acidobacteria,2JM3K@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158397_k127_116461_6	587753.EY04_23690	2.692e-48	194.0	2CNBY@1|root,32SGR@2|Bacteria,1NSIE@1224|Proteobacteria,1SMJW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_11	587753.EY04_23695	1.597e-23	117.0	2EAJV@1|root,334NM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_8	587753.EY04_23705	3.319e-45	187.0	2C2AP@1|root,2ZAZ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_3	449447.MAE_39620	3.112e-90	307.0	COG0265@1|root,COG0265@2|Bacteria,1G70N@1117|Cyanobacteria	1117|Cyanobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_12	197221.22296080	4.084e-21	110.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria	1117|Cyanobacteria	F	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158397_k127_116461_10	1279009.ADICEAN_02097	6.589e-27	130.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_116461_7	449447.MAE_12430	6.327e-46	193.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
SRR25158397_k127_116461_1	497964.CfE428DRAFT_0438	1.202e-121	438.0	COG1520@1|root,COG1572@1|root,COG3227@1|root,COG3391@1|root,COG4782@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG3391@2|Bacteria,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	DUF900,FTP,Peptidase_M36
SRR25158397_k127_1169046_9	105559.Nwat_1309	2.225e-92	313.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,1RZ9B@1236|Gammaproteobacteria,1WXG4@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1169046_4	330214.NIDE0582	3.152e-167	565.0	COG1752@1|root,COG3153@1|root,COG1752@2|Bacteria,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.59,2.3.1.82	ko:K14658,ko:K17840,ko:K18815	-	M00664	-	-	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Patatin
SRR25158397_k127_1169046_2	323261.Noc_1799	1.663e-214	675.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1WZ7Q@135613|Chromatiales	135613|Chromatiales	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158397_k127_1169046_5	317936.Nos7107_4358	4.644e-159	517.0	COG1858@1|root,COG1858@2|Bacteria,1G1X0@1117|Cyanobacteria	1117|Cyanobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158397_k127_1169046_11	472759.Nhal_1346	5.234e-15	81.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CCP_MauG,FG-GAP,UnbV_ASPIC,VCBS
SRR25158397_k127_1169046_7	472759.Nhal_1344	3.268e-134	446.0	COG2010@1|root,COG2010@2|Bacteria,1MVYK@1224|Proteobacteria,1SM11@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1169046_8	671143.DAMO_1304	1.256e-92	321.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158397_k127_1169046_12	489825.LYNGBM3L_50900	1.978e-12	80.0	COG1858@1|root,COG1858@2|Bacteria,1G6GR@1117|Cyanobacteria,1HDEP@1150|Oscillatoriales	1117|Cyanobacteria	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1169046_1	587753.EY04_15370	1.497e-236	749.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158397_k127_1169046_0	765912.Thimo_3423	0.0	1069.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,1RZ9B@1236|Gammaproteobacteria,1WXG4@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1169046_6	658187.LDG_8703	5.83e-139	463.0	COG3391@1|root,COG3391@2|Bacteria,1RA6R@1224|Proteobacteria,1SE8J@1236|Gammaproteobacteria,1JDB8@118969|Legionellales	118969|Legionellales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1169046_10	762376.AXYL_06345	1.673e-19	95.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,2VZQV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158397_k127_1169046_3	501479.ACNW01000089_gene2454	7.324e-173	583.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CHU_C,DUF11,Glug,NADase_NGA
SRR25158397_k127_1169046_13	1121129.KB903364_gene2954	3.269e-07	53.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1176049_2	1385517.N800_01535	2.857e-91	305.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1X3DG@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the aldehyde dehydrogenase family	betB	GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85	ko:K00130,ko:K00151,ko:K10217	ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00533,M00555,M00569	R02565,R02566,R02762,R03889,R04418,R05353	RC00080,RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_1176049_3	1278073.MYSTI_07223	3.208e-70	254.0	28HUE@1|root,2Z815@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1176049_1	762376.AXYL_02641	4.101e-121	397.0	COG3384@1|root,COG3384@2|Bacteria,1PUF4@1224|Proteobacteria,2VZW8@28216|Betaproteobacteria,3T6P8@506|Alcaligenaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.74,1.13.11.76	ko:K15059	ko00627,ko01120,map00627,map01120	-	R05405	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158397_k127_1176049_7	263358.VAB18032_17820	3.672e-49	194.0	COG3384@1|root,COG3384@2|Bacteria,2H395@201174|Actinobacteria	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15058	ko00627,ko01120,map00627,map01120	-	R05405	RC00387	ko00000,ko00001	-	-	-	LigB
SRR25158397_k127_1176049_8	666685.R2APBS1_1169	3.633e-40	167.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,1S5CQ@1236|Gammaproteobacteria,1X6F2@135614|Xanthomonadales	135614|Xanthomonadales	J	translation initiation inhibitor, yjgF family	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158397_k127_1176049_5	1479238.JQMZ01000001_gene112	1.165e-54	202.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2U7KU@28211|Alphaproteobacteria,43ZSG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Putative cyclase	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158397_k127_1176049_14	1144275.COCOR_02683	5.189e-09	67.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_1176049_13	1267535.KB906767_gene1432	6.438e-10	64.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158397_k127_1176049_11	1267535.KB906767_gene105	1.627e-24	117.0	COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158397_k127_1176049_9	1121430.JMLG01000019_gene1642	1.964e-29	125.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1176049_16	1121428.DESHY_40085___1	0.0001466	53.0	COG5662@1|root,COG5662@2|Bacteria,1U216@1239|Firmicutes,25N56@186801|Clostridia,2631J@186807|Peptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
SRR25158397_k127_1176049_15	1267533.KB906736_gene1243	3.772e-05	57.0	COG3595@1|root,COG3595@2|Bacteria,3Y7VI@57723|Acidobacteria,2JMY1@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158397_k127_1176049_6	1121405.dsmv_1158	6.125e-50	194.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158397_k127_1176049_4	436308.Nmar_1740	9.162e-57	202.0	COG0652@1|root,arCOG04767@2157|Archaea,41T32@651137|Thaumarchaeota	651137|Thaumarchaeota	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158397_k127_1176049_10	706587.Desti_1483	5.432e-29	129.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158397_k127_1176049_0	1519464.HY22_10895	4.529e-133	432.0	COG0473@1|root,COG0473@2|Bacteria,1FEMW@1090|Chlorobi	1090|Chlorobi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158397_k127_1176049_12	931277.C448_02441	1.725e-14	78.0	arCOG09205@1|root,arCOG09205@2157|Archaea,2XVYM@28890|Euryarchaeota,23VNM@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
SRR25158397_k127_1187269_3	1185876.BN8_03082	2.02e-07	61.0	29XWU@1|root,30JP9@2|Bacteria,4NNWG@976|Bacteroidetes,47PSI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1187269_1	925409.KI911562_gene1382	2.264e-79	276.0	COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,1J006@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158397_k127_1187269_2	1131730.BAVI_07471	1.33e-21	100.0	2ECKJ@1|root,336IM@2|Bacteria,1U9IB@1239|Firmicutes,4IJNY@91061|Bacilli,1ZCP1@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1187269_0	95619.PM1_0219430	0.0	1198.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	lhr	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158397_k127_1206473_0	1047013.AQSP01000123_gene1533	9.345e-104	362.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158397_k127_1206473_5	278963.ATWD01000001_gene1101	6.115e-20	105.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria,2JKG4@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1206473_6	204669.Acid345_0913	3.049e-08	68.0	COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1206473_1	580331.Thit_1277	5.434e-56	205.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,42FUI@68295|Thermoanaerobacterales	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158397_k127_1206473_3	316067.Geob_2653	6.79e-37	159.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
SRR25158397_k127_1206473_2	224324.aq_797	2.826e-51	200.0	COG0793@1|root,COG0793@2|Bacteria,2G3RT@200783|Aquificae	200783|Aquificae	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158397_k127_1206473_4	1304885.AUEY01000002_gene415	2.647e-35	144.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2WNEI@28221|Deltaproteobacteria,2MJKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
SRR25158397_k127_1216294_1	1189612.A33Q_3946	3.581e-64	235.0	COG0627@1|root,COG4188@1|root,COG0627@2|Bacteria,COG4188@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158397_k127_1216294_2	1297863.APJF01000010_gene3372	3.279e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,1NA4J@1224|Proteobacteria,2VE9U@28211|Alphaproteobacteria,3K1XE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_1216294_4	1250278.JQNQ01000001_gene1684	1.04e-22	107.0	COG1075@1|root,COG1075@2|Bacteria,4NIEZ@976|Bacteroidetes,1I0TU@117743|Flavobacteriia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
SRR25158397_k127_1216294_0	401053.AciPR4_0705	8.257e-167	553.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158397_k127_1216294_3	876269.ARWA01000001_gene1968	4.711e-36	153.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TSRP@28211|Alphaproteobacteria,3N9SC@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	PAS domain	divJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K07716,ko:K11357	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4
SRR25158397_k127_1216294_5	1134912.AJTV01000033_gene2267	2.613e-07	62.0	COG3161@1|root,COG3161@2|Bacteria,1RDSK@1224|Proteobacteria,2U80Y@28211|Alphaproteobacteria,3702X@31993|Methylocystaceae	28211|Alphaproteobacteria	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1223499_1	1173027.Mic7113_0525	4.167e-185	609.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
SRR25158397_k127_1223499_8	1122611.KB904010_gene6834	7.339e-06	59.0	COG1595@1|root,COG1595@2|Bacteria,2IRNG@201174|Actinobacteria,4EJHC@85012|Streptosporangiales	201174|Actinobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1223499_4	84531.JMTZ01000137_gene1432	4.438e-37	157.0	COG0860@1|root,COG3979@1|root,COG0860@2|Bacteria,COG3979@2|Bacteria,1QVSC@1224|Proteobacteria	1224|Proteobacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1223499_6	579137.Metvu_1510	1.217e-12	80.0	COG3291@1|root,arCOG03991@1|root,arCOG02508@2157|Archaea,arCOG03991@2157|Archaea	2157|Archaea	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM_6,NosD,PKD,PQQ_3
SRR25158397_k127_1223499_5	391008.Smal_2075	1.852e-32	143.0	COG0860@1|root,COG1318@1|root,COG0860@2|Bacteria,COG1318@2|Bacteria	2|Bacteria	K	COGs COG1318 transcriptional regulator protein	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K07745,ko:K18546,ko:K21471	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	CHAP,Cu_amine_oxidN1,GBS_Bsp-like,Glyco_hydro_25,Peptidase_C39_2,SH3_5,VanY,YSIRK_signal
SRR25158397_k127_1223499_7	1380356.JNIK01000011_gene1632	1.989e-11	76.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4EX5J@85013|Frankiales	201174|Actinobacteria	S	Laminin G domain	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
SRR25158397_k127_1223499_3	1051632.TPY_0717	9.656e-56	211.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158397_k127_1223499_2	1033740.CAEW01000016_gene2789	1.62e-77	280.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,26CU6@186818|Planococcaceae	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158397_k127_1223499_0	1123059.KB823013_gene502	2.667e-240	776.0	COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_1225403_0	555079.Toce_1670	0.0	1064.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158397_k127_1225403_10	504728.K649_01780	9.26e-10	63.0	COG2010@1|root,COG2010@2|Bacteria,1WI35@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,Dehyd-heme_bind
SRR25158397_k127_1225403_1	1340493.JNIF01000003_gene4649	2.507e-85	295.0	COG2010@1|root,COG2041@1|root,COG2010@2|Bacteria,COG2041@2|Bacteria,3Y7UP@57723|Acidobacteria	57723|Acidobacteria	C	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158397_k127_1225403_8	215803.DB30_7525	1.889e-19	104.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria,2YXF4@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_1225403_7	357808.RoseRS_4060	7.13e-22	112.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_1225403_9	404589.Anae109_1180	2.402e-19	98.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158397_k127_1225403_3	1123372.AUIT01000002_gene131	5.321e-54	201.0	COG0744@1|root,COG0744@2|Bacteria,2GHUC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRR25158397_k127_1225403_6	596151.DesfrDRAFT_3055	6.966e-31	137.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,2MG7G@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
SRR25158397_k127_1225403_2	1254432.SCE1572_02705	3.901e-84	309.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria,2YW9J@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HATPase_c,HisKA
SRR25158397_k127_1225403_5	913865.DOT_1371	3.301e-36	146.0	COG0637@1|root,COG0637@2|Bacteria,1UW2W@1239|Firmicutes,25M3W@186801|Clostridia,2664X@186807|Peptococcaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158397_k127_1225403_4	1123504.JQKD01000019_gene5545	5.08e-39	152.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,4AAG0@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158397_k127_1225896_6	468059.AUHA01000003_gene1524	7.545e-10	60.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,1IRUG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SRR25158397_k127_1225896_2	525904.Tter_1596	9.962e-95	314.0	COG3880@1|root,COG3880@2|Bacteria,2NPCX@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
SRR25158397_k127_1225896_0	1128421.JAGA01000003_gene2870	0.0	1071.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SRR25158397_k127_1225896_1	1128421.JAGA01000003_gene2871	4.76e-204	646.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SRR25158397_k127_1225896_4	649638.Trad_1024	6.125e-63	222.0	COG2010@1|root,COG2010@2|Bacteria,1WJ5T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SRR25158397_k127_1225896_5	204669.Acid345_3000	1.677e-62	226.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158397_k127_1225896_3	1340493.JNIF01000004_gene148	2.217e-64	230.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria	57723|Acidobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1244795_0	880073.Calab_3349	3.995e-68	252.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1244795_2	903818.KI912268_gene2839	5.501e-36	143.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158397_k127_1244795_1	562970.Btus_0876	3.51e-54	200.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,4I47R@91061|Bacilli,279PC@186823|Alicyclobacillaceae	91061|Bacilli	P	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158397_k127_1244795_3	1547437.LL06_13530	1.194e-13	75.0	COG5266@1|root,COG5266@2|Bacteria,1RA8J@1224|Proteobacteria,2U5BT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
SRR25158397_k127_1278914_1	1267535.KB906767_gene621	6.94e-53	190.0	COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158397_k127_1278914_2	1192034.CAP_5313	4.584e-29	130.0	COG4276@1|root,COG4276@2|Bacteria,1R0BS@1224|Proteobacteria,43CU7@68525|delta/epsilon subdivisions,2X81U@28221|Deltaproteobacteria,2Z3JC@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158397_k127_1278914_0	1540257.JQMW01000011_gene1585	2.05e-58	208.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,24CT6@186801|Clostridia,36RC3@31979|Clostridiaceae	186801|Clostridia	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158397_k127_1290190_5	1379270.AUXF01000001_gene2741	1.812e-91	340.0	COG3342@1|root,COG3342@2|Bacteria,1ZUQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SRR25158397_k127_1290190_0	929562.Emtol_0687	1.314e-178	576.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158397_k127_1290190_7	1232410.KI421428_gene1046	1.389e-80	280.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
SRR25158397_k127_1290190_1	1047013.AQSP01000123_gene1542	1.7e-153	502.0	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_1290190_15	690850.Desaf_3625	8.809e-31	128.0	COG3554@1|root,COG3554@2|Bacteria,1RA4K@1224|Proteobacteria	1224|Proteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158397_k127_1290190_3	867845.KI911784_gene2515	9.42e-113	380.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi,37528@32061|Chloroflexia	32061|Chloroflexia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158397_k127_1290190_6	1121015.N789_06825	4.733e-87	312.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,1XCCR@135614|Xanthomonadales	1236|Gammaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_1290190_10	436308.Nmar_1740	2.976e-54	199.0	COG0652@1|root,arCOG04767@2157|Archaea,41T32@651137|Thaumarchaeota	651137|Thaumarchaeota	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158397_k127_1290190_11	1219084.AP014508_gene424	6.149e-48	176.0	COG0315@1|root,COG0315@2|Bacteria,2GD56@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158397_k127_1290190_18	1382359.JIAL01000001_gene2222	1.329e-08	67.0	COG0746@1|root,COG0746@2|Bacteria,3Y5GH@57723|Acidobacteria,2JJWH@204432|Acidobacteriia	204432|Acidobacteriia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158397_k127_1290190_9	861299.J421_6133	7.284e-59	213.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	dcsG	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,RimK
SRR25158397_k127_1290190_14	136993.KB900626_gene3765	3.857e-39	150.0	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,2U9CN@28211|Alphaproteobacteria,37142@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158397_k127_1290190_2	266117.Rxyl_0136	3.517e-131	437.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4CQ4C@84995|Rubrobacteria	84995|Rubrobacteria	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158397_k127_1290190_13	32057.KB217478_gene2852	1.469e-40	166.0	COG1216@1|root,COG1216@2|Bacteria,1G0X3@1117|Cyanobacteria,1HK6N@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
SRR25158397_k127_1290190_12	1120999.JONM01000009_gene303	4.654e-46	171.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2VTA0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158397_k127_1290190_8	234267.Acid_4610	2.229e-65	231.0	COG2207@1|root,COG2207@2|Bacteria,3Y4S3@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158397_k127_1290190_4	713586.KB900536_gene377	1.805e-103	358.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,1T1T1@1236|Gammaproteobacteria,1X2QZ@135613|Chromatiales	135613|Chromatiales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158397_k127_1290190_16	220664.PFL_2027	8.5e-27	121.0	COG0500@1|root,COG2226@2|Bacteria,1QXCK@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_1292617_10	234267.Acid_3190	2.274e-47	186.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,3Y2NW@57723|Acidobacteria	57723|Acidobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158397_k127_1292617_0	706587.Desti_2041	6.031e-191	616.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158397_k127_1292617_12	1042156.CXIVA_11810	8.082e-22	98.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,36KID@31979|Clostridiaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158397_k127_1292617_1	944479.JQLX01000001_gene1219	4.387e-108	373.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria,2M6WN@213113|Desulfurellales	28221|Deltaproteobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158397_k127_1292617_3	234267.Acid_1799	1.151e-98	342.0	COG0384@1|root,COG0384@2|Bacteria,3Y7JN@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158397_k127_1292617_11	945550.VISI1226_06823	1.052e-40	160.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XUPI@135623|Vibrionales	135623|Vibrionales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158397_k127_1292617_9	56110.Oscil6304_5961	1.658e-47	179.0	COG1028@1|root,COG1028@2|Bacteria	56110.Oscil6304_5961|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1292617_5	867903.ThesuDRAFT_02308	2.096e-87	301.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WCG8@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158397_k127_1292617_8	570967.JMLV01000003_gene2253	5.301e-76	263.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2JPB2@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158397_k127_1292617_7	56780.SYN_00410	2.217e-77	279.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQE7@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158397_k127_1292617_4	671143.DAMO_0321	1.948e-98	336.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158397_k127_1292617_13	264462.Bd0198	8.71e-14	75.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MM@1224|Proteobacteria,42X37@68525|delta/epsilon subdivisions,2WSNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158397_k127_1292617_6	398767.Glov_2183	1.031e-82	288.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43U3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158397_k127_1292617_2	1121346.KB899846_gene34	4.385e-106	351.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,26QZ7@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158397_k127_1294559_2	1300345.LF41_2280	1.119e-88	301.0	COG2810@1|root,COG2810@2|Bacteria,1RFCH@1224|Proteobacteria	1224|Proteobacteria	V	stress, protein	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2,TerD
SRR25158397_k127_1294559_5	28072.Nos7524_4685	2.696e-15	89.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_1294559_1	522306.CAP2UW1_3032	2.059e-114	372.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VJXG@28216|Betaproteobacteria,1KQJK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158397_k127_1294559_3	28072.Nos7524_4685	5.109e-25	105.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_1294559_0	1384056.N787_14045	4.161e-236	751.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,1X3SK@135614|Xanthomonadales	135614|Xanthomonadales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158397_k127_130731_4	1173020.Cha6605_3883	4.593e-15	76.0	2E6NS@1|root,33197@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_130731_1	1121123.AUAO01000001_gene1068	3.549e-52	190.0	COG2267@1|root,COG2267@2|Bacteria,1QVFU@1224|Proteobacteria,2TYD9@28211|Alphaproteobacteria,2KGBN@204458|Caulobacterales	204458|Caulobacterales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158397_k127_130731_3	760117.JN27_04285	1.168e-18	94.0	COG2267@1|root,COG2267@2|Bacteria,1QVFU@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158397_k127_130731_0	1122604.JONR01000033_gene34	1.154e-63	228.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158397_k127_130731_2	1278073.MYSTI_05966	5.194e-37	161.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158397_k127_1323786_1	1229204.AMYY01000035_gene835	2.256e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,2UJ82@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1323786_0	1144275.COCOR_05170	1.552e-48	180.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1331928_1	861299.J421_1936	1.239e-123	405.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158397_k127_1331928_3	1122182.KB903825_gene537	9.286e-28	126.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4DBA8@85008|Micromonosporales	201174|Actinobacteria	T	Domain of unknown function (DUF4118)	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR25158397_k127_1331928_2	1122175.ATXU01000008_gene295	4.011e-56	205.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FM5Q@85023|Microbacteriaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_1331928_0	404589.Anae109_3101	2.543e-227	724.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158397_k127_1332820_13	649639.Bcell_0657	7.122e-08	64.0	28KG8@1|root,2ZA24@2|Bacteria,1V08Q@1239|Firmicutes,4HEUX@91061|Bacilli,1ZDB5@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1332820_9	1276756.AUEX01000015_gene1968	9.929e-18	92.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2VQPE@28216|Betaproteobacteria,4ADGF@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1332820_8	1123020.AUIE01000036_gene2700	3.048e-23	113.0	COG3485@1|root,COG3485@2|Bacteria,1QEWY@1224|Proteobacteria,1TBU7@1236|Gammaproteobacteria,1YJ2I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Dioxygenase	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C
SRR25158397_k127_1332820_12	641524.ADICYQ_3624	1.669e-09	66.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
SRR25158397_k127_1332820_4	1234364.AMSF01000045_gene1997	2.105e-92	341.0	COG4412@1|root,COG4733@1|root,COG4932@1|root,COG4412@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,1R1F7@1224|Proteobacteria,1T50E@1236|Gammaproteobacteria,1X534@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1332820_11	591167.Sfla_4807	6.93e-13	77.0	COG1309@1|root,COG1309@2|Bacteria,2HK4X@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	kstR2	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22108	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158397_k127_1332820_10	909663.KI867149_gene3434	6.136e-13	74.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,42V73@68525|delta/epsilon subdivisions,2WSD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158397_k127_1332820_0	1307761.L21SP2_3217	2.983e-265	840.0	COG0058@1|root,COG0058@2|Bacteria,2J5KC@203691|Spirochaetes	203691|Spirochaetes	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158397_k127_1332820_3	502025.Hoch_5321	4.323e-100	346.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43A4R@68525|delta/epsilon subdivisions,2X23J@28221|Deltaproteobacteria,2YUTA@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SRR25158397_k127_1332820_7	1380347.JNII01000005_gene2882	9.739e-26	125.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,2GPF1@201174|Actinobacteria	201174|Actinobacteria	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
SRR25158397_k127_1332820_1	706587.Desti_5232	2.534e-144	494.0	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	CP_1034	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
SRR25158397_k127_1332820_2	1183438.GKIL_3395	2.689e-134	474.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158397_k127_1332820_5	1340493.JNIF01000003_gene2146	2.738e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158397_k127_1332820_6	357808.RoseRS_3112	5.579e-32	139.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1344476_0	1121920.AUAU01000001_gene2279	0.0	1248.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_1344476_3	1384054.N790_02955	1.673e-44	179.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_1344476_4	1282360.ABAC460_05915	1.732e-18	98.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2KI46@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_1344476_2	1278073.MYSTI_05965	2.722e-50	193.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_1344476_1	234267.Acid_3157	5.222e-89	310.0	COG3488@1|root,COG3488@2|Bacteria,3Y3DB@57723|Acidobacteria	57723|Acidobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SRR25158397_k127_1344476_6	1334046.AYTB01000013_gene484	2.271e-14	85.0	COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,4HEEQ@91061|Bacilli,26D1F@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
SRR25158397_k127_1344476_5	243274.THEMA_00820	8.313e-18	88.0	COG1725@1|root,COG1725@2|Bacteria,2GDGX@200918|Thermotogae	200918|Thermotogae	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158397_k127_1350114_0	211165.AJLN01000016_gene2180	4.202e-135	448.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JK99@1189|Stigonemataceae	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
SRR25158397_k127_1350114_2	390989.JOEG01000017_gene6236	2.172e-42	165.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria,4DDCM@85008|Micromonosporales	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158397_k127_1350114_3	426114.THI_2361	6.677e-39	155.0	2DZKR@1|root,32VDB@2|Bacteria,1RBUG@1224|Proteobacteria,2VQA7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1350114_4	67352.JODS01000055_gene2241	3.711e-13	83.0	COG1404@1|root,COG2247@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,2IATQ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1350114_1	452637.Oter_2265	1.884e-65	252.0	COG3391@1|root,COG3391@2|Bacteria,46UA2@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,NHL
SRR25158397_k127_135052_1	5111.M1W467	1.06e-38	152.0	COG0302@1|root,KOG2698@2759|Eukaryota,38CYY@33154|Opisthokonta,3NVRA@4751|Fungi,3QP0W@4890|Ascomycota,214NU@147550|Sordariomycetes,3TGZ3@5125|Hypocreales,3G5GK@34397|Clavicipitaceae	4751|Fungi	H	GTP cyclohydrolase	-	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006066,GO:0006082,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046394,GO:0046483,GO:0046655,GO:0046656,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YGR267C,iND750.YGR267C	GTP_cyclohydroI
SRR25158397_k127_135052_0	716544.wcw_1271	5.089e-205	662.0	COG1960@1|root,COG1960@2|Bacteria,2JFSS@204428|Chlamydiae	204428|Chlamydiae	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158397_k127_1351713_0	292459.STH604	6.861e-79	272.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia	186801|Clostridia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158397_k127_1351713_2	215803.DB30_4900	3.608e-74	266.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_1351713_1	1340493.JNIF01000003_gene1293	6.981e-77	281.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
SRR25158397_k127_1351713_5	240015.ACP_2579	1.365e-17	90.0	COG3468@1|root,COG3468@2|Bacteria,3Y4BG@57723|Acidobacteria,2JJ56@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1351713_3	926566.Terro_4184	1.308e-69	247.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria,2JICH@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158397_k127_1351713_4	610130.Closa_4233	3.554e-43	167.0	COG2169@1|root,COG2333@1|root,COG2169@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,21ZGP@1506553|Lachnoclostridium	186801|Clostridia	K	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
SRR25158397_k127_1380789_1	1280692.AUJL01000031_gene1980	1.009e-92	321.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,36E39@31979|Clostridiaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158397_k127_1380789_5	1449355.JQNR01000005_gene2674	2.223e-09	72.0	COG4934@1|root,COG4934@2|Bacteria,2H5BC@201174|Actinobacteria	201174|Actinobacteria	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
SRR25158397_k127_1380789_3	443143.GM18_0409	3.501e-50	203.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.78	ko:K01218,ko:K13276	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH26	-	CARDB,CHB_HEX_C_1,F5_F8_type_C,Laminin_G_3
SRR25158397_k127_1380789_2	330214.NIDE3081	1.823e-82	283.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158397_k127_1380789_0	234267.Acid_1595	5.04e-95	327.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158397_k127_1380789_4	234267.Acid_1594	9.855e-31	125.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158397_k127_1383168_6	1487923.DP73_11840	1.764e-37	154.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,2600X@186807|Peptococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158397_k127_1383168_0	240015.ACP_2445	7.485e-166	541.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158397_k127_1383168_7	502025.Hoch_5415	4.646e-24	111.0	COG2154@1|root,COG2154@2|Bacteria,1RIEN@1224|Proteobacteria,43765@68525|delta/epsilon subdivisions,2X24N@28221|Deltaproteobacteria,2YW4N@29|Myxococcales	28221|Deltaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158397_k127_1383168_4	575564.HMPREF0014_01597	2.23e-49	194.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,3NKP6@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
SRR25158397_k127_1383168_3	234267.Acid_2379	3.426e-61	243.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158397_k127_1383168_2	697282.Mettu_4061	1.165e-124	412.0	COG2124@1|root,COG2124@2|Bacteria,1MWRZ@1224|Proteobacteria,1RYXU@1236|Gammaproteobacteria,1XFK6@135618|Methylococcales	135618|Methylococcales	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158397_k127_1383168_1	857087.Metme_2718	9.205e-151	497.0	COG2010@1|root,COG2010@2|Bacteria,1MVYK@1224|Proteobacteria,1RQH2@1236|Gammaproteobacteria,1XEU7@135618|Methylococcales	135618|Methylococcales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1383168_9	1122179.KB890419_gene61	4.556e-18	85.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1ITUM@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158397_k127_1383168_10	1200792.AKYF01000011_gene3790	1.653e-15	84.0	COG0167@1|root,COG0167@2|Bacteria,1TRFE@1239|Firmicutes,4HDHX@91061|Bacilli,26WBA@186822|Paenibacillaceae	91061|Bacilli	F	Dihydroorotate dehydrogenase	-	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158397_k127_1384433_3	927677.ALVU02000001_gene4336	5.87e-24	117.0	COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
SRR25158397_k127_1384433_2	118163.Ple7327_1968	6.077e-61	226.0	COG2931@1|root,COG2931@2|Bacteria,1GHAU@1117|Cyanobacteria,3VMMX@52604|Pleurocapsales	1117|Cyanobacteria	Q	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158397_k127_1384433_0	1121015.N789_06345	2.316e-165	546.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_1384433_1	390989.JOEG01000013_gene2562	1.236e-100	331.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158397_k127_138953_3	326427.Cagg_1001	3.493e-07	61.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,376IX@32061|Chloroflexia	32061|Chloroflexia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_138953_0	1379698.RBG1_1C00001G1265	3.14e-137	450.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_138953_1	1278073.MYSTI_03221	3.309e-61	234.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SRR25158397_k127_138953_2	234267.Acid_2564	1.017e-07	57.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1401241_7	436229.JOEH01000007_gene3942	1.065e-17	90.0	COG2267@1|root,COG2267@2|Bacteria,2H83P@201174|Actinobacteria,2NJRF@228398|Streptacidiphilus	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158397_k127_1401241_0	379066.GAU_1210	8.43e-86	305.0	COG4409@1|root,COG4409@2|Bacteria,1ZUBR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1401241_5	1123487.KB892865_gene1492	1.729e-34	139.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,2KWNA@206389|Rhodocyclales	206389|Rhodocyclales	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158397_k127_1401241_2	1267535.KB906767_gene4050	7.505e-49	187.0	2DN75@1|root,32VXD@2|Bacteria,3Y7CA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1401241_3	926566.Terro_1697	3.719e-46	183.0	COG0666@1|root,COG0666@2|Bacteria,3Y6WC@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SRR25158397_k127_1401241_8	1117318.PRUB_19012	7.973e-15	85.0	COG3595@1|root,COG3595@2|Bacteria,1RI1P@1224|Proteobacteria,1RRZW@1236|Gammaproteobacteria,2Q0AP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158397_k127_1401241_4	1519464.HY22_02720	3.336e-45	173.0	COG0546@1|root,COG0546@2|Bacteria,1FDVN@1090|Chlorobi	1090|Chlorobi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158397_k127_1401241_1	935863.AWZR01000014_gene2956	4.379e-62	224.0	COG0451@1|root,COG0451@2|Bacteria,1NQXJ@1224|Proteobacteria,1T0SB@1236|Gammaproteobacteria,1XD1F@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SRR25158397_k127_1410354_6	296591.Bpro_4463	5.944e-06	57.0	COG0745@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R5EN@1224|Proteobacteria,2VP0K@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
SRR25158397_k127_1410354_2	1033737.CAEV01000110_gene1159	3.173e-39	153.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36I5H@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158397_k127_1410354_1	1449126.JQKL01000035_gene2187	3.859e-55	196.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,26986@186813|unclassified Clostridiales	186801|Clostridia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158397_k127_1410354_3	717231.Flexsi_2312	9.006e-25	112.0	COG1024@1|root,COG1024@2|Bacteria,2GFIS@200930|Deferribacteres	200930|Deferribacteres	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158397_k127_1410354_0	1382306.JNIM01000001_gene2570	4.203e-253	789.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158397_k127_1410354_4	291112.PAU_00183	3.175e-19	95.0	COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,1RRDC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase	yihX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050308	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158397_k127_1415292_0	263358.VAB18032_05250	4.526e-197	631.0	COG2268@1|root,COG2268@2|Bacteria,2GKB2@201174|Actinobacteria,4D8F8@85008|Micromonosporales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158397_k127_1415292_5	33876.JNXY01000053_gene7881	1.467e-12	77.0	2A865@1|root,30X71@2|Bacteria,2I82Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
SRR25158397_k127_1415292_4	1174528.JH992898_gene2614	1.293e-22	115.0	COG4995@1|root,COG4995@2|Bacteria,1GDW4@1117|Cyanobacteria	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158397_k127_1415292_3	861299.J421_1529	1.329e-28	126.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158397_k127_1415292_2	1453505.JASY01000011_gene4119	9.047e-56	220.0	COG3291@1|root,COG3291@2|Bacteria,4NIED@976|Bacteroidetes,1I093@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1415292_1	483219.LILAB_30160	6.977e-135	460.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158397_k127_1415292_6	2903.EOD41850	1.286e-06	61.0	KOG2183@1|root,KOG4287@1|root,KOG2183@2759|Eukaryota,KOG4287@2759|Eukaryota	2759|Eukaryota	M	pectin acetylesterase activity	-	-	3.1.1.98,3.4.14.2,3.4.16.2	ko:K01276,ko:K01285,ko:K19882	ko04310,ko04614,ko04974,map04310,map04614,map04974	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000,ko01002	-	-	-	Aldo_ket_red,PAE,Peptidase_S28
SRR25158397_k127_1436555_0	1144275.COCOR_04617	1.034e-145	497.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,439XQ@68525|delta/epsilon subdivisions,2X1V0@28221|Deltaproteobacteria,2YZ8J@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158397_k127_1436555_1	1254432.SCE1572_52405	3.933e-61	240.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
SRR25158397_k127_1436555_3	1121382.JQKG01000003_gene4270	3.645e-06	59.0	COG3868@1|root,COG3868@2|Bacteria	2|Bacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_114
SRR25158397_k127_1436555_2	883126.HMPREF9710_01598	1.025e-40	169.0	COG2120@1|root,COG2120@2|Bacteria,1RKX6@1224|Proteobacteria	1224|Proteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158397_k127_1438321_2	926690.KE386573_gene1707	1.607e-47	177.0	COG0477@1|root,arCOG00130@2157|Archaea,2XT8X@28890|Euryarchaeota,23TJU@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_1438321_1	706587.Desti_2456	3.835e-66	237.0	COG3591@1|root,COG3591@2|Bacteria,1QYRA@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the peptidase S1B family	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_1,Trypsin_2
SRR25158397_k127_1438321_0	84531.JMTZ01000011_gene3099	3.654e-200	631.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1X3QG@135614|Xanthomonadales	135614|Xanthomonadales	G	COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158397_k127_1456224_4	1173025.GEI7407_1480	1.374e-36	147.0	COG4191@1|root,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1HH3C@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158397_k127_1456224_1	643473.KB235930_gene2284	2.529e-130	445.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIE5@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_1456224_3	158189.SpiBuddy_0623	3.741e-54	199.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_1456224_2	1173027.Mic7113_1679	2.433e-66	248.0	COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_1456224_9	3067.XP_002956828.1	0.0002551	49.0	COG4870@1|root,KOG1543@2759|Eukaryota	2759|Eukaryota	O	cysteine-type peptidase activity	-	-	3.4.18.1,3.4.22.15,3.4.22.38	ko:K01365,ko:K01371,ko:K08568,ko:K16292	ko04140,ko04142,ko04145,ko04210,ko04380,ko04612,ko04620,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04380,map04612,map04620,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00537,ko01000,ko01002,ko03110	-	-	-	Granulin,Inhibitor_I29,Peptidase_C1
SRR25158397_k127_1456224_0	240015.ACP_1767	5.35e-132	436.0	COG2876@1|root,COG2876@2|Bacteria,3Y2SV@57723|Acidobacteria,2JHNF@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158397_k127_1456224_5	880073.Calab_0023	3.783e-22	101.0	COG1605@1|root,COG1605@2|Bacteria,2NRZ4@2323|unclassified Bacteria	2|Bacteria	E	Chorismate mutase type II	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04092,ko:K04093,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRR25158397_k127_1456224_6	1144275.COCOR_05604	1.442e-14	87.0	2EQIM@1|root,33I4N@2|Bacteria,1NJZ4@1224|Proteobacteria,42XX4@68525|delta/epsilon subdivisions,2WST7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158397_k127_1456224_8	1074488.AGBX01000007_gene2030	0.0001266	54.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria,4FC76@85020|Dermabacteraceae	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158397_k127_1467873_6	1159870.KB907784_gene984	6.434e-06	48.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,3T6CU@506|Alcaligenaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	yvdD_1	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158397_k127_1467873_1	864702.OsccyDRAFT_3010	6.544e-109	363.0	COG3227@1|root,COG3227@2|Bacteria,1G3KW@1117|Cyanobacteria,1H7JS@1150|Oscillatoriales	1117|Cyanobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
SRR25158397_k127_1467873_7	1185876.BN8_00772	1.444e-05	59.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB,TIG
SRR25158397_k127_1467873_5	1120959.ATXF01000011_gene210	1.414e-09	65.0	COG4319@1|root,COG4319@2|Bacteria,2IRHC@201174|Actinobacteria,4FQIA@85023|Microbacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158397_k127_1467873_0	748247.AZKH_3538	2.728e-223	712.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,2KU9R@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158397_k127_1467873_2	1305735.JAFT01000005_gene3241	2.193e-54	196.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,2PC88@252301|Oceanicola	28211|Alphaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158397_k127_1467873_4	760568.Desku_0640	2.356e-17	83.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,262US@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158397_k127_1467873_3	278963.ATWD01000001_gene3561	6.892e-38	146.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158397_k127_1498273_7	1487953.JMKF01000043_gene2573	2.236e-06	61.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1G04W@1117|Cyanobacteria,1H940@1150|Oscillatoriales	1117|Cyanobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH
SRR25158397_k127_1498273_4	1121946.AUAX01000039_gene5751	1.523e-44	185.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4D9AK@85008|Micromonosporales	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M36
SRR25158397_k127_1498273_2	1128421.JAGA01000002_gene324	2.84e-54	216.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2NQNP@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	chvG	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
SRR25158397_k127_1498273_0	1123073.KB899242_gene947	1.635e-66	237.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria,1X3MS@135614|Xanthomonadales	135614|Xanthomonadales	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158397_k127_1498273_1	1121481.AUAS01000015_gene2252	1.062e-59	216.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158397_k127_1498273_5	324602.Caur_3322	3.068e-31	131.0	COG1051@1|root,COG1051@2|Bacteria,2G74M@200795|Chloroflexi,375UB@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158397_k127_1498273_8	1121355.KB903379_gene745	6.587e-06	48.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158397_k127_1498273_6	1218074.BAXZ01000035_gene5207	4.842e-18	93.0	2E53M@1|root,32ZWP@2|Bacteria,1N5H5@1224|Proteobacteria,2VWFE@28216|Betaproteobacteria,1K91B@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	ko:K11918	-	-	-	-	ko00000,ko02044	-	-	-	-
SRR25158397_k127_1498273_3	448385.sce9346	2.797e-52	199.0	COG3522@1|root,COG3522@2|Bacteria,1RD5T@1224|Proteobacteria,43F3D@68525|delta/epsilon subdivisions,2X38C@28221|Deltaproteobacteria,2YUTK@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
SRR25158397_k127_1499667_10	709032.Sulku_0274	1.381e-06	54.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2YP9Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158397_k127_1499667_5	1519464.HY22_11610	4.044e-28	115.0	COG0713@1|root,COG0713@2|Bacteria,1FFEB@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158397_k127_1499667_0	204669.Acid345_1305	3.545e-175	572.0	COG1009@1|root,COG1009@2|Bacteria,3Y2VS@57723|Acidobacteria,2JIG7@204432|Acidobacteriia	204432|Acidobacteriia	CP	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158397_k127_1499667_1	671143.DAMO_2705	2.169e-170	550.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158397_k127_1499667_2	706587.Desti_2761	7.275e-109	369.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2MSIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158397_k127_1499667_12	717231.Flexsi_0499	9.889e-05	48.0	COG5336@1|root,COG5336@2|Bacteria,2GG0Q@200930|Deferribacteres	200930|Deferribacteres	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158397_k127_1499667_3	1047013.AQSP01000119_gene1285	2.386e-53	196.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158397_k127_1499667_8	903818.KI912268_gene3080	1.468e-11	68.0	COG0636@1|root,COG0636@2|Bacteria,3Y5G6@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158397_k127_1499667_9	1280948.HY36_04020	1.086e-06	54.0	2EGHT@1|root,33A9W@2|Bacteria,1NHZD@1224|Proteobacteria,2V70B@28211|Alphaproteobacteria,43YSN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1499667_13	760192.Halhy_3025	0.0003797	52.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4NUFW@976|Bacteroidetes,1IZ0P@117747|Sphingobacteriia	976|Bacteroidetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158397_k127_1499667_11	1340434.AXVA01000005_gene4820	7.272e-06	54.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
SRR25158397_k127_1499667_4	32057.KB217478_gene907	2.06e-28	124.0	COG1682@1|root,COG1682@2|Bacteria,1G0IN@1117|Cyanobacteria,1HKMP@1161|Nostocales	1117|Cyanobacteria	GM	Transport permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158397_k127_1499667_7	203124.Tery_0666	8.245e-12	78.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1HAPX@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
SRR25158397_k127_1499667_6	593750.Metfor_0743	9.365e-15	90.0	COG1520@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02538@1|root,arCOG06792@1|root,arCOG09475@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,arCOG06792@2157|Archaea,arCOG09475@2157|Archaea,2Y7Q0@28890|Euryarchaeota,2NAJS@224756|Methanomicrobia	28890|Euryarchaeota	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_3
SRR25158397_k127_151316_9	1254432.SCE1572_21925	6.314e-36	159.0	COG4270@1|root,COG4270@2|Bacteria,1Q7N5@1224|Proteobacteria,4337R@68525|delta/epsilon subdivisions,2WYHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_151316_8	487521.OCU_21600	1.166e-39	162.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,2391H@1762|Mycobacteriaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158397_k127_151316_7	566466.NOR53_2430	2.984e-49	202.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1J646@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop
SRR25158397_k127_151316_0	497964.CfE428DRAFT_0230	4.034e-150	527.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,46TGZ@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158397_k127_151316_5	234267.Acid_4535	1.219e-66	243.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158397_k127_151316_11	1121935.AQXX01000063_gene3214	0.0003809	48.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,1SBUW@1236|Gammaproteobacteria,1XMR6@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_151316_3	671143.DAMO_2095	7.276e-79	293.0	COG0744@1|root,COG0744@2|Bacteria,2NNMB@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158397_k127_151316_4	1123368.AUIS01000005_gene382	3.335e-68	250.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164	PBP1_TM,Transgly,Transpeptidase,UB2H
SRR25158397_k127_151316_6	46429.BV95_00598	3.911e-52	200.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,2UG7N@28211|Alphaproteobacteria,2K47E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_151316_10	1121104.AQXH01000001_gene1231	2.39e-27	120.0	COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158397_k127_151316_1	379066.GAU_2343	1.127e-148	489.0	COG3653@1|root,COG3653@2|Bacteria,1ZTDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158397_k127_151316_2	317655.Sala_1467	7.635e-82	275.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2K1RR@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158397_k127_1533257_0	1254432.SCE1572_07155	1.601e-175	564.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,2YWBV@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158397_k127_1533257_3	1123355.JHYO01000025_gene2104	2.857e-66	246.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,371I7@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Stimulus-sensing domain	chvG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
SRR25158397_k127_1533257_1	685778.AORL01000021_gene767	6.329e-69	243.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,2JZVH@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_1533257_4	1238450.VIBNISOn1_1070044	9.418e-06	58.0	COG3291@1|root,COG3591@1|root,COG3291@2|Bacteria,COG3591@2|Bacteria,1QDPR@1224|Proteobacteria,1RN6D@1236|Gammaproteobacteria,1XWET@135623|Vibrionales	135623|Vibrionales	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Trypsin_2
SRR25158397_k127_1533257_2	404589.Anae109_0984	2.202e-66	246.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YX41@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158397_k127_1547875_4	697282.Mettu_1186	4.077e-08	66.0	COG1999@1|root,COG1999@2|Bacteria,1R725@1224|Proteobacteria,1S1UW@1236|Gammaproteobacteria,1XFRR@135618|Methylococcales	135618|Methylococcales	C	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,SCO1-SenC
SRR25158397_k127_1547875_1	247490.KSU1_D0506	5.567e-136	462.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158397_k127_1547875_0	247490.KSU1_D0507	0.0	1833.0	COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1547875_2	1136417.AZWE01000042_gene143	9.689e-17	89.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D8MU@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_1547875_3	446470.Snas_2659	1.284e-09	68.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_154969_9	1121127.JAFA01000006_gene5687	7.993e-22	103.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,1K9J4@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158397_k127_154969_8	1134413.ANNK01000065_gene2702	7.735e-31	133.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158397_k127_154969_10	211165.AJLN01000085_gene1633	1.218e-10	66.0	COG3187@1|root,COG3187@2|Bacteria,1G7C2@1117|Cyanobacteria	1117|Cyanobacteria	O	LppP/LprE lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_21,META
SRR25158397_k127_154969_0	861299.J421_3672	8.209e-110	375.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_154969_6	861299.J421_3671	3.295e-56	205.0	2F2ZI@1|root,33VUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_154969_4	861299.J421_3670	1.032e-69	247.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Beta-lactamase,Beta-lactamase2
SRR25158397_k127_154969_5	1343739.PAP_06205	2.977e-60	222.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,242SN@183968|Thermococci	183968|Thermococci	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_154969_2	194439.CT2259	9.015e-98	326.0	COG2171@1|root,COG2171@2|Bacteria,1FDRM@1090|Chlorobi	1090|Chlorobi	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158397_k127_154969_3	861299.J421_3424	1.387e-82	283.0	COG0329@1|root,COG0329@2|Bacteria,1ZSM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158397_k127_154969_7	888059.HMPREF9071_1361	1.561e-41	170.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia,1EQHJ@1016|Capnocytophaga	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158397_k127_154969_1	926566.Terro_2252	4.671e-102	350.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158397_k127_1552809_0	159087.Daro_1261	9.38e-75	280.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,2VM5H@28216|Betaproteobacteria,2KX6W@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_1552809_3	1380386.JIAW01000017_gene3192	5.564e-21	109.0	COG0438@1|root,COG0438@2|Bacteria,2ICGJ@201174|Actinobacteria,23845@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_1552809_1	497964.CfE428DRAFT_3066	6.472e-50	191.0	COG1216@1|root,COG1216@2|Bacteria,46VR2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_1553593_8	861299.J421_1124	5.127e-13	83.0	2EPV2@1|root,33HFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1553593_7	2325.TKV_c08460	1.944e-19	104.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,42FS7@68295|Thermoanaerobacterales	186801|Clostridia	M	Serine protease with a broad substrate specificity	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
SRR25158397_k127_1553593_11	204669.Acid345_3657	0.0004741	53.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
SRR25158397_k127_1553593_3	234267.Acid_3157	8.803e-91	315.0	COG3488@1|root,COG3488@2|Bacteria,3Y3DB@57723|Acidobacteria	57723|Acidobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SRR25158397_k127_1553593_6	1300345.LF41_1764	3.949e-35	156.0	COG5400@1|root,COG5400@2|Bacteria,1NDMP@1224|Proteobacteria,1SFZS@1236|Gammaproteobacteria,1XD1Z@135614|Xanthomonadales	135614|Xanthomonadales	S	conserved protein UCP033924	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1553593_10	1122985.HMPREF1991_01472	0.0003237	54.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,2FNUV@200643|Bacteroidia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,STN
SRR25158397_k127_1553593_1	1047013.AQSP01000123_gene1523	3.507e-106	384.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_1553593_0	861299.J421_6004	8.513e-117	381.0	COG3279@1|root,COG3279@2|Bacteria,1ZUUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_1553593_2	861299.J421_6005	9.224e-101	339.0	COG2972@1|root,COG2972@2|Bacteria,1ZURN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_1553593_5	861299.J421_4047	3.004e-51	198.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
SRR25158397_k127_1553593_4	880073.Calab_3561	3.515e-60	222.0	COG1225@1|root,COG1225@2|Bacteria,2NS0C@2323|unclassified Bacteria	2|Bacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158397_k127_1553593_9	518766.Rmar_1745	9.159e-05	48.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1745|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1555723_11	267608.RSc1802	1.529e-37	149.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2W2U0@28216|Betaproteobacteria,1KDM1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158397_k127_1555723_12	1048339.KB913029_gene5052	2.233e-05	56.0	COG2931@1|root,COG2931@2|Bacteria,2GKS7@201174|Actinobacteria,4EX57@85013|Frankiales	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
SRR25158397_k127_1555723_2	29581.BW37_05076	8.005e-122	414.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,47743@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_1555723_1	869210.Marky_0500	9.061e-132	431.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158397_k127_1555723_3	1122939.ATUD01000001_gene577	2.683e-98	355.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1555723_9	1128398.Curi_c27910	1.647e-42	177.0	COG1573@1|root,COG1573@2|Bacteria,1V58R@1239|Firmicutes,248TH@186801|Clostridia	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158397_k127_1555723_0	1382304.JNIL01000001_gene3015	5.191e-152	491.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,279ER@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158397_k127_1555723_6	1340493.JNIF01000003_gene2147	8.734e-74	261.0	COG2382@1|root,COG2382@2|Bacteria,3Y68C@57723|Acidobacteria	57723|Acidobacteria	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158397_k127_1555723_8	357808.RoseRS_4322	1.25e-53	192.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi,375VA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158397_k127_1555723_10	1127673.GLIP_0017	8.366e-39	157.0	COG3595@1|root,COG3595@2|Bacteria,1RFCY@1224|Proteobacteria,1S5RB@1236|Gammaproteobacteria,467PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158397_k127_1555723_5	448385.sce7885	5.876e-83	291.0	COG1233@1|root,COG1233@2|Bacteria,1QXT4@1224|Proteobacteria,43C5J@68525|delta/epsilon subdivisions,2X7FU@28221|Deltaproteobacteria,2YUIG@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158397_k127_1555723_7	247490.KSU1_C0316	5.816e-64	250.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,2J515@203682|Planctomycetes	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRR25158397_k127_1568703_4	1356852.N008_15325	5.855e-12	80.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,47RJR@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
SRR25158397_k127_1568703_0	314230.DSM3645_25619	1.223e-166	536.0	COG0821@1|root,COG0821@2|Bacteria,2IXN9@203682|Planctomycetes	203682|Planctomycetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158397_k127_1568703_1	338963.Pcar_2454	8.583e-35	141.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158397_k127_1568703_2	1047013.AQSP01000088_gene1637	1.757e-21	96.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158397_k127_1568703_3	909663.KI867150_gene229	3.478e-18	86.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,42WJ7@68525|delta/epsilon subdivisions,2WRB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1577770_2	404589.Anae109_0513	1.548e-77	275.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KO	TIGRFAM Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
SRR25158397_k127_1577770_6	404589.Anae109_0514	3.016e-23	112.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
SRR25158397_k127_1577770_4	1379698.RBG1_1C00001G1651	9.158e-46	177.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_16935	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158397_k127_1577770_7	118168.MC7420_6305	2.096e-17	94.0	COG0299@1|root,COG0299@2|Bacteria,1G11D@1117|Cyanobacteria,1H8P1@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.purN	Formyl_trans_N
SRR25158397_k127_1577770_1	290397.Adeh_0473	2.383e-131	439.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria,2YTZM@29|Myxococcales	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158397_k127_1577770_0	290397.Adeh_0474	7.667e-151	486.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2YTV5@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
SRR25158397_k127_1577770_5	404589.Anae109_0517	2.34e-28	121.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158397_k127_1577770_3	404589.Anae109_0518	4.138e-64	227.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,2YTV0@29|Myxococcales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158397_k127_1578221_0	1094980.Mpsy_1985	3.847e-140	460.0	COG0249@1|root,arCOG02897@2157|Archaea,2XT0M@28890|Euryarchaeota,2N9EU@224756|Methanomicrobia	224756|Methanomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158397_k127_1578221_3	1396418.BATQ01000070_gene740	7.638e-51	195.0	COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,2ITMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158397_k127_1578221_8	1121440.AUMA01000015_gene1848	4.552e-07	63.0	COG2199@1|root,COG4191@1|root,COG2199@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1
SRR25158397_k127_1578221_4	880073.Calab_3797	6.138e-42	177.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,HisKA_3,PAS_9,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
SRR25158397_k127_1578221_1	391625.PPSIR1_35762	3.314e-65	243.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	ddpA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158397_k127_1578221_2	391625.PPSIR1_35762	1.77e-64	239.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	ddpA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158397_k127_1578221_7	930166.CD58_03755	6.102e-09	69.0	COG2732@1|root,COG2732@2|Bacteria,1QR1J@1224|Proteobacteria,1SU9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
SRR25158397_k127_1578221_6	1000565.METUNv1_02902	7.499e-28	123.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,2KWVU@206389|Rhodocyclales	206389|Rhodocyclales	F	Guanyl-specific ribonuclease Sa	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
SRR25158397_k127_1578221_5	1034769.KB910518_gene1170	3.772e-33	141.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_1586996_4	204669.Acid345_4390	1.673e-106	378.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158397_k127_1586996_2	204669.Acid345_4350	2.648e-136	448.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158397_k127_1586996_12	234267.Acid_5658	2.438e-09	69.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1586996_13	161528.ED21_24181	7.428e-09	69.0	COG5010@1|root,COG5010@2|Bacteria,1R7S3@1224|Proteobacteria,2U39S@28211|Alphaproteobacteria,2KEAR@204457|Sphingomonadales	204457|Sphingomonadales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1586996_6	1242864.D187_009909	4.603e-83	299.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
SRR25158397_k127_1586996_5	266117.Rxyl_2548	1.071e-97	327.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158397_k127_1586996_11	744980.TRICHSKD4_5343	3.315e-13	72.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	metal-binding protein	nqrF	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRR25158397_k127_1586996_14	1247726.MIM_c18550	2.962e-07	58.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,3T45X@506|Alcaligenaceae	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158397_k127_1586996_10	268407.PWYN_24560	4.128e-16	88.0	COG2755@1|root,COG2755@2|Bacteria,1V76B@1239|Firmicutes,4HGIN@91061|Bacilli,2764W@186822|Paenibacillaceae	91061|Bacilli	E	Lysophospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158397_k127_1586996_9	1286631.X805_30960	4.275e-25	115.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
SRR25158397_k127_1586996_3	251221.35214933	3.733e-117	389.0	COG0113@1|root,COG0113@2|Bacteria,1G0YH@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158397_k127_1586996_1	1122611.KB903939_gene313	5.793e-137	473.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2H5BJ@201174|Actinobacteria	201174|Actinobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158397_k127_1586996_7	1121481.AUAS01000002_gene3509	7.592e-42	169.0	28QBS@1|root,2ZCUB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1586996_0	502025.Hoch_1577	2.024e-173	576.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_1586996_15	883126.HMPREF9710_03904	3.435e-05	52.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158397_k127_1586996_8	242619.PG_2046	4.071e-41	163.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,2FP2A@200643|Bacteroidia,22X8C@171551|Porphyromonadaceae	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,B3_4,TilS_C
SRR25158397_k127_1588458_4	1167006.UWK_01979	2.222e-14	88.0	2DYVX@1|root,34BD3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1588458_3	1000565.METUNv1_03002	5.613e-29	130.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,NodS,ParBc,Polysacc_deac_1
SRR25158397_k127_1588458_0	667014.Thein_0873	2.383e-132	452.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GH4Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158397_k127_1588458_2	547144.HydHO_1226	1.205e-58	221.0	COG0181@1|root,COG0181@2|Bacteria,2G3T1@200783|Aquificae	200783|Aquificae	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158397_k127_1588458_1	667014.Thein_1414	2.443e-94	321.0	COG0373@1|root,COG0373@2|Bacteria,2GHMP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158397_k127_1591580_3	234267.Acid_7677	7.793e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158397_k127_1591580_0	234267.Acid_4393	4.63e-163	548.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1591580_5	398579.Spea_2762	1.521e-17	88.0	COG3184@1|root,COG3184@2|Bacteria,1N1QU@1224|Proteobacteria,1T0MS@1236|Gammaproteobacteria,2QDW3@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
SRR25158397_k127_1591580_4	1121019.AUMN01000009_gene1868	9.252e-31	134.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158397_k127_1591580_2	883126.HMPREF9710_04979	8.693e-68	248.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,2WE5M@28216|Betaproteobacteria,4771T@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
SRR25158397_k127_1591580_1	886293.Sinac_6536	1.104e-84	286.0	COG0567@1|root,COG0567@2|Bacteria,2IWRF@203682|Planctomycetes	203682|Planctomycetes	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158397_k127_1596731_0	1122604.JONR01000018_gene1066	4.47e-131	442.0	COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QWC6@1224|Proteobacteria,1RPDJ@1236|Gammaproteobacteria,1X4ZV@135614|Xanthomonadales	135614|Xanthomonadales	COT	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_3,cNMP_binding
SRR25158397_k127_1596731_3	888052.HMPREF9006_1270	1.71e-13	81.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D52E@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158397_k127_1596731_1	1340493.JNIF01000003_gene1755	1.235e-109	390.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158397_k127_1596731_2	1340493.JNIF01000003_gene1756	2.227e-101	349.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
SRR25158397_k127_1608349_6	671143.DAMO_1381	1.686e-06	51.0	COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K19591,ko:K22491	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
SRR25158397_k127_1608349_2	671143.DAMO_1641	3.586e-48	185.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	rfaF	-	2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28	ko:K02841,ko:K02843,ko:K02849,ko:K03271,ko:K03272,ko:K03273	ko00540,ko01100,map00540,map01100	M00064,M00080	R05644,R05645,R05646,R05647,R09768,R09769,R09771	RC00002,RC00017,RC00078,RC00434	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
SRR25158397_k127_1608349_4	1125863.JAFN01000001_gene527	3.156e-33	148.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158397_k127_1608349_5	1125863.JAFN01000001_gene3418	5.566e-33	147.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158397_k127_1608349_0	1267534.KB906757_gene860	7.002e-72	258.0	COG1519@1|root,COG1519@2|Bacteria,3Y3X5@57723|Acidobacteria,2JI61@204432|Acidobacteriia	204432|Acidobacteriia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158397_k127_1608349_7	1437882.AZRU01000022_gene6327	0.0008198	50.0	COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,1S570@1236|Gammaproteobacteria,1YGM7@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	ECF sigma factor	fecI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1608349_1	1121930.AQXG01000012_gene3203	1.064e-69	250.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158397_k127_1629737_3	35754.JNYJ01000032_gene1767	1.188e-39	157.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4DBJX@85008|Micromonosporales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158397_k127_1629737_4	485918.Cpin_6804	4.407e-22	101.0	2CK2Y@1|root,32SBF@2|Bacteria,4NTZD@976|Bacteroidetes,1ITGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Photosynthetic reaction centre cytochrome C subunit	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	CytoC_RC
SRR25158397_k127_1629737_2	192952.MM_1168	2.212e-50	194.0	COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,2N98D@224756|Methanomicrobia	224756|Methanomicrobia	M	Polysaccharide biosynthesis protein	rfbD-1	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158397_k127_1629737_1	765420.OSCT_0651	2.935e-183	612.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158397_k127_1629737_5	69042.WH5701_09209	1.063e-05	59.0	COG4916@1|root,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2,TIR_2
SRR25158397_k127_1629737_0	396588.Tgr7_2123	1.616e-296	921.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158397_k127_1641406_14	215803.DB30_0358	6.511e-17	95.0	COG0823@1|root,COG1520@1|root,COG3055@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Ig_3,PD40,PKD,Peptidase_S8
SRR25158397_k127_1641406_11	118161.KB235922_gene1026	1.673e-17	97.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G0YS@1117|Cyanobacteria	1117|Cyanobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158397_k127_1641406_1	1121920.AUAU01000004_gene638	2.721e-115	397.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158397_k127_1641406_16	1122931.AUAE01000019_gene889	2.487e-13	82.0	COG5002@1|root,COG5002@2|Bacteria,4NDTV@976|Bacteroidetes,2FP04@200643|Bacteroidia,22W6T@171551|Porphyromonadaceae	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	covS	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS
SRR25158397_k127_1641406_10	1306174.JODP01000005_gene1671	1.946e-18	98.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria	201174|Actinobacteria	T	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
SRR25158397_k127_1641406_0	1089550.ATTH01000001_gene1237	4.924e-132	432.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158397_k127_1641406_9	1400520.LFAB_08425	5.211e-30	129.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae	91061|Bacilli	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158397_k127_1641406_17	292.DM42_6507	5.307e-10	72.0	COG0664@1|root,COG4271@1|root,COG0664@2|Bacteria,COG4271@2|Bacteria,1R4Z7@1224|Proteobacteria,2VWIN@28216|Betaproteobacteria,1KBXX@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like,cNMP_binding
SRR25158397_k127_1641406_12	502025.Hoch_0716	3.682e-17	89.0	COG0847@1|root,COG0847@2|Bacteria,1PER2@1224|Proteobacteria,42WAS@68525|delta/epsilon subdivisions,2WWG3@28221|Deltaproteobacteria,2Z1FU@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM Exonuclease RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158397_k127_1641406_4	484019.THA_512	7.96e-58	208.0	COG0461@1|root,COG0461@2|Bacteria,2GD2M@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158397_k127_1641406_13	1333856.L686_15580	4.936e-17	93.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1YZW6@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158397_k127_1641406_2	1123355.JHYO01000006_gene2221	3.339e-102	351.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,36ZJT@31993|Methylocystaceae	28211|Alphaproteobacteria	E	HMGL-like	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158397_k127_1641406_15	634497.HAH_2528	1.755e-15	89.0	COG0824@1|root,arCOG01137@2157|Archaea,2XZ99@28890|Euryarchaeota,23WUB@183963|Halobacteria	183963|Halobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158397_k127_1641406_8	1415779.JOMH01000001_gene124	1.535e-36	154.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158397_k127_1641406_3	234267.Acid_3826	2.959e-94	339.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158397_k127_1641406_5	321327.CYA_0380	1.101e-47	181.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H0CQ@1129|Synechococcus	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158397_k127_1641406_7	1121920.AUAU01000025_gene2317	1.452e-37	150.0	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1641406_6	1142394.PSMK_08700	1.086e-40	173.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1
SRR25158397_k127_16450_3	765420.OSCT_0910	1.253e-60	234.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
SRR25158397_k127_16450_1	1192034.CAP_5545	1.179e-122	400.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158397_k127_16450_0	1254432.SCE1572_30430	6.811e-237	740.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_16450_2	58123.JOFJ01000004_gene1873	1.936e-98	341.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4EHBQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_1675537_1	1144275.COCOR_02646	1.149e-89	302.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_1675537_2	1297742.A176_02905	3.808e-46	189.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
SRR25158397_k127_1675537_0	502025.Hoch_1577	8.135e-157	527.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_1676435_8	1267533.KB906734_gene4042	9.119e-09	59.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158397_k127_1676435_2	880073.Calab_0162	2.032e-71	246.0	COG5405@1|root,COG5405@2|Bacteria,2NP72@2323|unclassified Bacteria	2|Bacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158397_k127_1676435_5	502025.Hoch_6830	1.472e-36	150.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,43B0F@68525|delta/epsilon subdivisions,2X6EI@28221|Deltaproteobacteria,2Z3AT@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2,S4
SRR25158397_k127_1676435_3	649638.Trad_2508	2.482e-71	252.0	COG2197@1|root,COG2197@2|Bacteria,1WJU0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_1676435_4	926560.KE387023_gene3856	2.385e-69	248.0	COG4585@1|root,COG4585@2|Bacteria,1WK2H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158397_k127_1676435_6	1122919.KB905560_gene1481	5.347e-29	134.0	COG0666@1|root,COG0666@2|Bacteria,1V657@1239|Firmicutes,4HIDE@91061|Bacilli,26WY6@186822|Paenibacillaceae	91061|Bacilli	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
SRR25158397_k127_1676435_7	1224746.B932_1381	1.722e-09	66.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158397_k127_1676435_0	272562.CA_C1815	2.763e-149	482.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,36DUE@31979|Clostridiaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158397_k127_1676435_1	1278073.MYSTI_03819	1.201e-139	459.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
SRR25158397_k127_1694107_3	246197.MXAN_0087	1.428e-78	273.0	COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,42QCH@68525|delta/epsilon subdivisions,2WK35@28221|Deltaproteobacteria,2YXVI@29|Myxococcales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_1694107_2	471852.Tcur_0033	2.704e-102	354.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4EICB@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158397_k127_1694107_4	1038867.AXAY01000011_gene5238	5.384e-56	207.0	COG5397@1|root,COG5397@2|Bacteria,1PJM3@1224|Proteobacteria,2U1M6@28211|Alphaproteobacteria,3JXFR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1488,NTP_transf_8
SRR25158397_k127_1694107_0	1242864.D187_002113	4.338e-191	625.0	COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria	1224|Proteobacteria	O	Peptidase M6, immune inhibitor A	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
SRR25158397_k127_1694107_6	1122621.ATZA01000023_gene4227	0.0001941	51.0	COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,4NQK9@976|Bacteroidetes,1ISQH@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158397_k127_1694107_5	1041159.AZUW01000018_gene783	3.816e-36	147.0	2DM0H@1|root,316A1@2|Bacteria,1N0X9@1224|Proteobacteria,2UEZ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1694107_1	234267.Acid_2647	4.411e-142	461.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_1697655_1	903818.KI912268_gene729	4.299e-75	283.0	COG1232@1|root,COG1232@2|Bacteria,3Y3KX@57723|Acidobacteria	57723|Acidobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158397_k127_1697655_0	243090.RB2115	6.258e-189	603.0	COG4262@1|root,COG4262@2|Bacteria,2J4XV@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158397_k127_1697655_3	1192034.CAP_1496	2.951e-12	72.0	2DI1Z@1|root,301RV@2|Bacteria,1NM7Q@1224|Proteobacteria,433HJ@68525|delta/epsilon subdivisions,2WXZG@28221|Deltaproteobacteria,2Z1QD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158397_k127_1697655_2	903818.KI912268_gene725	2.671e-53	201.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158397_k127_1702512_3	861299.J421_1529	4.983e-18	94.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158397_k127_1702512_4	1207075.PputUW4_03538	2.867e-06	57.0	COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho- dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains	rfaH	GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
SRR25158397_k127_1702512_2	1192124.LIG30_4830	3.67e-30	136.0	COG2327@1|root,COG2327@2|Bacteria,1R84F@1224|Proteobacteria,2VN09@28216|Betaproteobacteria,1K3TX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR25158397_k127_1702512_1	28229.ND2E_2293	2.155e-70	254.0	COG0845@1|root,COG0845@2|Bacteria,1R50D@1224|Proteobacteria,1RRYM@1236|Gammaproteobacteria,2Q7X5@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158397_k127_1702512_0	1535422.ND16A_1927	1.12e-77	263.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1SYJN@1236|Gammaproteobacteria,2Q7VX@267889|Colwelliaceae	1236|Gammaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_1703382_8	1380394.JADL01000010_gene4317	8.937e-08	64.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria,2U63Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158397_k127_1703382_4	204669.Acid345_1498	3.979e-83	282.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_1703382_6	903818.KI912269_gene523	1.971e-25	120.0	COG1538@1|root,COG1538@2|Bacteria,3Y54R@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158397_k127_1703382_1	243231.GSU1331	6.451e-98	349.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,43SU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
SRR25158397_k127_1703382_0	269798.CHU_1504	0.0	1119.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47N7N@768503|Cytophagia	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
SRR25158397_k127_1703382_9	1142394.PSMK_22550	0.0001371	52.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
SRR25158397_k127_1703382_3	1033802.SSPSH_001573	1.442e-86	300.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
SRR25158397_k127_1703382_2	378806.STAUR_0942	2.663e-93	314.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158397_k127_1703382_5	856793.MICA_1256	9.11e-29	120.0	COG3350@1|root,COG3350@2|Bacteria,1NEA9@1224|Proteobacteria	1224|Proteobacteria	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1703382_7	1123368.AUIS01000033_gene1380	1.002e-21	96.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158397_k127_1704421_1	1304885.AUEY01000057_gene677	2.873e-84	295.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2MIGW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158397_k127_1704421_3	234267.Acid_0744	1.135e-07	56.0	COG0236@1|root,COG0236@2|Bacteria,3Y5XA@57723|Acidobacteria	57723|Acidobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158397_k127_1704421_0	1234364.AMSF01000071_gene1756	8.906e-102	353.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3GS@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_1704421_2	1121920.AUAU01000006_gene355	1.733e-14	78.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158397_k127_1706006_7	1499967.BAYZ01000015_gene6576	1.519e-28	122.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Peripla_BP_3
SRR25158397_k127_1706006_10	502025.Hoch_1983	1.717e-11	67.0	2DREH@1|root,33BDY@2|Bacteria,1Q6K1@1224|Proteobacteria,433AU@68525|delta/epsilon subdivisions,2WXFM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1706006_5	502025.Hoch_1982	4.042e-40	160.0	COG1978@1|root,COG1978@2|Bacteria	2|Bacteria	S	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	prdB	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRR25158397_k127_1706006_12	1342302.JASC01000014_gene1469	1.384e-10	66.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,3ZWRH@60136|Sulfitobacter	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K02479,ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158397_k127_1706006_3	1128421.JAGA01000003_gene3260	1.709e-44	176.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_1706006_9	378806.STAUR_3413	1.711e-11	73.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria,439MQ@68525|delta/epsilon subdivisions,2X4YU@28221|Deltaproteobacteria,2YZV4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1706006_6	251221.35214334	1.838e-30	140.0	COG0400@1|root,COG0400@2|Bacteria,1G525@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	sll1284	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158397_k127_1706006_1	903818.KI912268_gene1402	4.101e-168	536.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158397_k127_1706006_11	630626.EBL_c08930	1.788e-11	72.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Regulatory protein recX	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158397_k127_1706006_2	1121930.AQXG01000003_gene2458	1.687e-54	204.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
SRR25158397_k127_1706006_0	1242864.D187_003508	2.375e-265	843.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158397_k127_1706006_13	682795.AciX8_3725	4.026e-06	59.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
SRR25158397_k127_1706006_8	452637.Oter_4002	2.542e-13	81.0	COG0500@1|root,COG2226@2|Bacteria,46W0U@74201|Verrucomicrobia,3KA15@414999|Opitutae	2|Bacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158397_k127_1708029_6	671143.DAMO_3050	4.472e-15	77.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_1708029_3	880072.Desac_2292	3.958e-34	143.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MQJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158397_k127_1708029_0	485913.Krac_9213	2.494e-212	687.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158397_k127_1708029_2	324602.Caur_3493	4.371e-89	306.0	COG0673@1|root,COG0673@2|Bacteria,2G6V1@200795|Chloroflexi,375S4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158397_k127_1708029_1	319225.Plut_1740	2.883e-102	353.0	COG1109@1|root,COG1109@2|Bacteria,1FDKY@1090|Chlorobi	1090|Chlorobi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158397_k127_1708029_5	1385511.N783_08550	2.068e-15	82.0	2C3PV@1|root,3307H@2|Bacteria,1VJ1P@1239|Firmicutes,4HPE6@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF2834)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2834
SRR25158397_k127_1708029_4	2002.JOEQ01000004_gene2972	1.691e-17	90.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4EJRM@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158397_k127_1709711_3	887929.HMP0721_1437	3.396e-29	131.0	COG1051@1|root,COG1443@1|root,COG1051@2|Bacteria,COG1443@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,25WKI@186806|Eubacteriaceae	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158397_k127_1709711_0	497964.CfE428DRAFT_1132	5.182e-210	663.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SRR25158397_k127_1709711_2	1254432.SCE1572_09515	1.256e-56	202.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
SRR25158397_k127_1709711_1	1278073.MYSTI_06522	1.219e-65	252.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR25158397_k127_1716431_2	1210884.HG799464_gene11252	6.422e-09	61.0	COG5569@1|root,COG5569@2|Bacteria,2J3PB@203682|Planctomycetes	203682|Planctomycetes	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
SRR25158397_k127_1716431_1	867903.ThesuDRAFT_01144	2.587e-87	296.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,247XS@186801|Clostridia	186801|Clostridia	IQ	Dehydrogenase	ydaD	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158397_k127_1716431_0	471854.Dfer_2714	4.158e-125	407.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158397_k127_1722259_1	62928.azo1540	5.666e-134	431.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,2KXXF@206389|Rhodocyclales	206389|Rhodocyclales	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158397_k127_1722259_6	861299.J421_1786	3.549e-40	170.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158397_k127_1722259_3	378806.STAUR_7452	1.953e-72	269.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria,2YV31@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158397_k127_1722259_4	379066.GAU_3632	1.232e-54	209.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_1722259_7	1121127.JAFA01000009_gene7032	3.087e-24	109.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,1K202@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRR25158397_k127_1722259_8	1033730.CAHG01000013_gene1456	3.047e-10	66.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DNTF@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_1722259_10	1120934.KB894414_gene3748	1.076e-06	56.0	COG1396@1|root,COG1396@2|Bacteria,2IBV6@201174|Actinobacteria,4EF56@85010|Pseudonocardiales	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158397_k127_1722259_9	1317118.ATO8_04286	8.939e-07	57.0	COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,2UCHN@28211|Alphaproteobacteria,4KMTH@93682|Roseivivax	28211|Alphaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158397_k127_1722259_2	323848.Nmul_A1872	1.161e-75	268.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,37224@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
SRR25158397_k127_1722259_0	338963.Pcar_2000	7.546e-135	438.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43S11@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF933)	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158397_k127_1722259_5	997346.HMPREF9374_3130	8.036e-46	175.0	COG1073@1|root,COG1073@2|Bacteria,1V1RV@1239|Firmicutes,4HGDR@91061|Bacilli,27B3I@186824|Thermoactinomycetaceae	91061|Bacilli	S	alpha/beta hydrolase fold	M1-904	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158397_k127_1733254_1	1047013.AQSP01000138_gene1041	2.041e-24	119.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659	-	ko:K04744,ko:K09774,ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2,1.B.42.1	-	iAF987.Gmet_2474,iECO111_1330.ECO111_4695,iECSF_1327.ECSF_3725,iEcSMS35_1347.EcSMS35_4260	KdgM,OstA,OstA_2,OstA_C
SRR25158397_k127_1733254_3	1349767.GJA_1327	2.443e-09	63.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria,474VB@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	prepilin-type N-terminal cleavage methylation	gspG4	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158397_k127_1733254_0	234267.Acid_2125	1.299e-30	131.0	COG1216@1|root,COG4976@1|root,COG1216@2|Bacteria,COG4976@2|Bacteria,3Y878@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_1733254_2	864702.OsccyDRAFT_5039	8.807e-15	78.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,1H8SW@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158397_k127_1733254_4	1385935.N836_22455	1.514e-07	56.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158397_k127_1733697_4	395495.Lcho_2627	8.655e-29	119.0	COG1999@1|root,COG1999@2|Bacteria,1RF8N@1224|Proteobacteria	1224|Proteobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158397_k127_1733697_3	247490.KSU1_D0505	2.52e-44	184.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
SRR25158397_k127_1733697_2	247490.KSU1_D0504	9.752e-52	207.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
SRR25158397_k127_1733697_0	251221.35210997	3.877e-113	372.0	COG1131@1|root,COG1131@2|Bacteria,1G0BQ@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_1733697_1	251221.35210998	4.37e-58	225.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1736059_3	498761.HM1_1902	3.437e-40	173.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158397_k127_1736059_1	192952.MM_3198	1.744e-111	375.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
SRR25158397_k127_1736059_2	1278073.MYSTI_01846	1.247e-51	190.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158397_k127_1736059_0	926549.KI421517_gene2980	4.662e-231	741.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158397_k127_1737156_1	570967.JMLV01000002_gene1584	5.213e-128	421.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,2JRRJ@204441|Rhodospirillales	204441|Rhodospirillales	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158397_k127_1737156_0	697282.Mettu_0563	2.211e-285	893.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX1M@1236|Gammaproteobacteria,1XG7H@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158397_k127_1737156_2	1005048.CFU_3678	1.829e-28	120.0	COG3437@1|root,COG3437@2|Bacteria,1PDX2@1224|Proteobacteria,2VMIS@28216|Betaproteobacteria,476BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
SRR25158397_k127_1755079_3	1242864.D187_006336	1.762e-48	176.0	COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales	28221|Deltaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158397_k127_1755079_0	215803.DB30_3367	2.504e-114	397.0	COG4219@1|root,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria,4380Y@68525|delta/epsilon subdivisions,2X3AY@28221|Deltaproteobacteria,2YV6Q@29|Myxococcales	28221|Deltaproteobacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158397_k127_1755079_2	1297742.A176_07321	9.62e-61	223.0	COG4219@1|root,COG4219@2|Bacteria,1P0K4@1224|Proteobacteria	1224|Proteobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1755079_1	502025.Hoch_3164	7.662e-99	359.0	COG2304@1|root,COG4676@1|root,COG4783@1|root,COG2304@2|Bacteria,COG4676@2|Bacteria,COG4783@2|Bacteria,1PCRX@1224|Proteobacteria,433WB@68525|delta/epsilon subdivisions,2X9AU@28221|Deltaproteobacteria,2YX4K@29|Myxococcales	28221|Deltaproteobacteria	E	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
SRR25158397_k127_1767736_0	555088.DealDRAFT_1362	1.156e-115	380.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,42JQI@68298|Syntrophomonadaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158397_k127_1767736_2	648996.Theam_0382	1.052e-56	202.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158397_k127_1767736_1	1537994.JQFW01000015_gene1338	2.05e-115	398.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,464W2@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	aminopeptidase	pepN	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158397_k127_1767736_6	697282.Mettu_0184	0.0008146	43.0	2E4QQ@1|root,32ZJA@2|Bacteria,1QMVQ@1224|Proteobacteria,1TK66@1236|Gammaproteobacteria,1XGWD@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1767736_5	43989.cce_3112	9.776e-13	70.0	2E46S@1|root,32Z2Q@2|Bacteria,1G73R@1117|Cyanobacteria,3KKRF@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1767736_4	63737.Npun_R5488	6.051e-16	79.0	2E4DR@1|root,32Z92@2|Bacteria,1G9TM@1117|Cyanobacteria,1HPVP@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1767736_3	926566.Terro_3293	1.5e-34	141.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158397_k127_1767736_7	1463841.JOIR01000018_gene1017	0.0008496	48.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1791393_0	1242864.D187_009631	1.297e-200	666.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1PEJF@1224|Proteobacteria,433Y5@68525|delta/epsilon subdivisions,2X2KM@28221|Deltaproteobacteria,2YXZ5@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SRR25158397_k127_1791393_2	1144275.COCOR_06776	6.261e-21	106.0	COG3349@1|root,COG3349@2|Bacteria,1QVG4@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	-	-	-	-	-	-	-	-	-	-	-	-	ADC
SRR25158397_k127_1791393_1	272123.Anacy_0442	3.493e-149	495.0	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	-	-	1.3.5.5	ko:K02293	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04786,R04787,R07510,R09652,R09653,R09654	RC01214,RC01958,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC,Amino_oxidase,NAD_binding_8
SRR25158397_k127_1809564_5	1297742.A176_04905	1.24e-23	110.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2Z1XZ@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,EF-hand_5,Metallophos
SRR25158397_k127_1809564_1	1303518.CCALI_01017	5.192e-71	253.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158397_k127_1809564_4	1121127.JAFA01000004_gene1486	1.114e-42	177.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,1K0MP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_1809564_2	1292034.OR37_02470	1.977e-57	224.0	28NMK@1|root,2ZBN3@2|Bacteria,1R4AD@1224|Proteobacteria,2U00H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	amj	-	-	-	-	-	-	-	-	-	-	-	Amj
SRR25158397_k127_1809564_0	1128421.JAGA01000001_gene2321	5.607e-74	273.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_1809564_3	748247.AZKH_3606	4.807e-49	189.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VJVY@28216|Betaproteobacteria,2KY04@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_1810571_0	234267.Acid_3259	5.42e-237	743.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158397_k127_1814738_8	616991.JPOO01000003_gene698	9.996e-34	138.0	COG2318@1|root,COG2318@2|Bacteria,4NNW4@976|Bacteroidetes,1I28C@117743|Flavobacteriia	976|Bacteroidetes	J	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_1814738_13	756272.Plabr_2724	0.0005382	51.0	COG2010@1|root,COG2010@2|Bacteria,2IZC1@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158397_k127_1814738_12	572480.Arnit_0855	3.183e-16	90.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,42TJB@68525|delta/epsilon subdivisions,2YPS9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04314	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRR25158397_k127_1814738_9	1219035.NT2_06_01310	2.592e-29	127.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U9DV@28211|Alphaproteobacteria,2K4JG@204457|Sphingomonadales	204457|Sphingomonadales	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158397_k127_1814738_2	1121272.KB903249_gene2326	4.987e-56	205.0	COG1024@1|root,COG1024@2|Bacteria,2IEXB@201174|Actinobacteria,4DJ3Q@85008|Micromonosporales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA3_1	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158397_k127_1814738_10	42256.RradSPS_0054	4.05e-21	109.0	COG2333@1|root,COG2333@2|Bacteria,2I4B4@201174|Actinobacteria	201174|Actinobacteria	S	competence protein COMEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
SRR25158397_k127_1814738_6	246197.MXAN_1196	2.687e-38	153.0	COG1652@1|root,COG3409@1|root,COG1652@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K07126,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	CW_binding_2,LysM,PG_binding_1,Sel1
SRR25158397_k127_1814738_1	1242864.D187_000937	5.983e-100	333.0	COG4711@1|root,COG4711@2|Bacteria,1R9Y5@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2391
SRR25158397_k127_1814738_11	927677.ALVU02000001_gene1407	1.215e-18	95.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1814738_4	247634.GPB2148_2290	4.643e-48	188.0	COG2199@1|root,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	ydaM	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016740,GO:0016772,GO:0016779,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043900,GO:0043902,GO:0044093,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051252,GO:0052621,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1903506,GO:2000112,GO:2001141	2.7.7.65	ko:K19707,ko:K21088	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko03021	-	-	-	GGDEF,PAS_4,PAS_8,PAS_9
SRR25158397_k127_1814738_3	557598.LHK_03116	1.705e-52	206.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,2KRD6@206351|Neisseriales	206351|Neisseriales	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_1814738_0	357808.RoseRS_3205	4.163e-111	367.0	COG0604@1|root,COG0604@2|Bacteria,2G5MI@200795|Chloroflexi,376YR@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158397_k127_1814738_7	1166948.JPZL01000001_gene3111	1.876e-36	145.0	COG5592@1|root,COG5592@2|Bacteria,1ND3D@1224|Proteobacteria,1SPP8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hemerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158397_k127_1814738_5	1077972.ARGLB_116_00130	3.369e-43	163.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158397_k127_1827257_4	227882.SAV_4161	5.701e-16	89.0	COG2370@1|root,COG2370@2|Bacteria,2I8N8@201174|Actinobacteria	201174|Actinobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
SRR25158397_k127_1827257_1	1123276.KB893301_gene4159	9.318e-65	246.0	COG0715@1|root,COG0715@2|Bacteria,4NIKI@976|Bacteroidetes,47MTE@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158397_k127_1827257_2	1237149.C900_03640	4.467e-27	113.0	COG5470@1|root,COG5470@2|Bacteria,4NUEC@976|Bacteroidetes,47V9R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158397_k127_1827257_0	234267.Acid_3288	8.324e-87	296.0	COG3865@1|root,COG3865@2|Bacteria,3Y4UB@57723|Acidobacteria	57723|Acidobacteria	H	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
SRR25158397_k127_1827257_3	391600.ABRU01000050_gene221	5.529e-26	114.0	COG0772@1|root,COG0772@2|Bacteria,1N2AA@1224|Proteobacteria,2UDQK@28211|Alphaproteobacteria,2KJA1@204458|Caulobacterales	204458|Caulobacterales	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1860508_1	1122217.KB899566_gene476	6.156e-103	343.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H278@909932|Negativicutes	909932|Negativicutes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158397_k127_1860508_10	429009.Adeg_0477	7.704e-06	57.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,42F03@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1,SH3_3,SLT
SRR25158397_k127_1860508_8	335543.Sfum_3705	6.302e-12	77.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_1860508_2	316274.Haur_1627	2.159e-80	278.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158397_k127_1860508_0	584708.Apau_0039	5.336e-170	542.0	COG0538@1|root,COG0538@2|Bacteria,3TACN@508458|Synergistetes	508458|Synergistetes	C	isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158397_k127_1860508_5	240016.ABIZ01000001_gene2120	7.297e-44	166.0	COG1943@1|root,COG1943@2|Bacteria,46VEW@74201|Verrucomicrobia,2IVQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1860508_9	457570.Nther_2043	2.345e-07	62.0	COG1664@1|root,COG1664@2|Bacteria,1VBC3@1239|Firmicutes,24NSR@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1860508_6	1379698.RBG1_1C00001G1704	1.392e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1860508_3	96561.Dole_2132	4.854e-79	271.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2MJC9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_1860508_4	469383.Cwoe_4634	4.381e-51	192.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158397_k127_1860508_7	1123401.JHYQ01000045_gene3372	5.114e-30	124.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales	72273|Thiotrichales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158397_k127_1871038_3	861299.J421_2331	1.135e-29	131.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667,HlyD_3
SRR25158397_k127_1871038_5	1125718.HMPREF1318_2324	0.0002418	49.0	COG1848@1|root,COG1848@2|Bacteria,2GUAN@201174|Actinobacteria,4D66P@85005|Actinomycetales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_1871038_0	1122221.JHVI01000015_gene1714	2.287e-53	200.0	COG1600@1|root,COG1600@2|Bacteria,1WJ6B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1730,Fer4_16,HEAT,HEAT_2
SRR25158397_k127_1871038_2	247490.KSU1_C0103	2.499e-47	186.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158397_k127_1871038_1	1157490.EL26_05445	3.79e-53	203.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli,278J9@186823|Alicyclobacillaceae	91061|Bacilli	S	DNA polymerase alpha chain like domain	php	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158397_k127_1871038_4	1408437.JNJN01000025_gene664	9.413e-15	79.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,25UTF@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158397_k127_1871469_13	266835.14026827	1.214e-23	106.0	COG1522@1|root,COG1522@2|Bacteria,1RBPB@1224|Proteobacteria,2U6S5@28211|Alphaproteobacteria,43JJN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158397_k127_1871469_6	1321778.HMPREF1982_01776	6.371e-60	224.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_1871469_1	690850.Desaf_1515	2.532e-188	595.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,43AQP@68525|delta/epsilon subdivisions,2X64P@28221|Deltaproteobacteria,2MGWY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158397_k127_1871469_5	1183438.GKIL_2545	7.197e-70	245.0	COG5637@1|root,COG5637@2|Bacteria,1G2FS@1117|Cyanobacteria	1117|Cyanobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158397_k127_1871469_4	234267.Acid_2317	7.454e-82	283.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158397_k127_1871469_2	392500.Swoo_2854	5.965e-125	420.0	COG0457@1|root,COG0457@2|Bacteria,1PBYW@1224|Proteobacteria,1SWS0@1236|Gammaproteobacteria,2QDGR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR25158397_k127_1871469_10	1047013.AQSP01000139_gene2398	2.78e-53	207.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	lytC_1	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SLH
SRR25158397_k127_1871469_15	1232410.KI421428_gene1047	2.13e-13	84.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,43V6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SRR25158397_k127_1871469_12	338963.Pcar_1692	2.659e-24	115.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43RXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158397_k127_1871469_7	338963.Pcar_1691	1.283e-59	214.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158397_k127_1871469_11	1121033.AUCF01000009_gene1087	7.236e-40	159.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria,2UFTW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_1871469_8	882082.SaccyDRAFT_2868	3.061e-59	222.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4E2QJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	phbB	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158397_k127_1871469_0	246194.CHY_0659	1.237e-273	874.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24E00@186801|Clostridia,42FQ1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158397_k127_1871469_16	56107.Cylst_5718	1.202e-11	78.0	299J7@1|root,2ZWMQ@2|Bacteria,1G69M@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1871469_3	518766.Rmar_2306	6.731e-97	321.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158397_k127_1871469_18	388399.SSE37_03175	0.0007048	51.0	COG3391@1|root,COG3391@2|Bacteria,1MXJJ@1224|Proteobacteria,2TTH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,NHL
SRR25158397_k127_1871469_14	562743.JH976438_gene2046	1.614e-20	94.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158397_k127_1871469_9	243231.GSU1631	6.137e-54	201.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria,43TQ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158397_k127_1871469_17	861299.J421_3183	3.427e-08	54.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158397_k127_1873856_2	314345.SPV1_05312	1.819e-114	376.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475	TGT
SRR25158397_k127_1873856_4	1499967.BAYZ01000074_gene2162	3.841e-21	97.0	COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase, YajC	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158397_k127_1873856_1	204669.Acid345_0146	1.657e-124	417.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158397_k127_1873856_3	1382359.JIAL01000001_gene986	7.463e-70	252.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158397_k127_1873856_0	290397.Adeh_3930	5.807e-143	459.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2YXS2@29|Myxococcales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
SRR25158397_k127_1881884_2	1248917.ANFX01000011_gene167	3.143e-40	167.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158397_k127_1881884_0	1131269.AQVV01000013_gene1720	5.803e-101	344.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_1881884_3	1121438.JNJA01000021_gene1340	2.48e-16	94.0	COG1216@1|root,COG1216@2|Bacteria,1R11B@1224|Proteobacteria,43D5D@68525|delta/epsilon subdivisions,2X8C3@28221|Deltaproteobacteria,2MA1N@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SRR25158397_k127_1881884_1	448385.sce9308	8.542e-52	190.0	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,43ACX@68525|delta/epsilon subdivisions,2X5SX@28221|Deltaproteobacteria,2Z14T@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_1886209_2	1033734.CAET01000026_gene1017	6.142e-39	156.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158397_k127_1886209_1	665952.HMPREF1015_00158	1.632e-87	310.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus	91061|Bacilli	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158397_k127_1886209_0	42256.RradSPS_0401	3.586e-89	303.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158397_k127_1886209_3	204669.Acid345_0553	1.311e-31	129.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158397_k127_1888704_3	1120999.JONM01000004_gene3676	4.139e-30	127.0	COG3896@1|root,COG3896@2|Bacteria,1NEN0@1224|Proteobacteria,2VY3P@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
SRR25158397_k127_1888704_1	861299.J421_0773	6.914e-95	320.0	COG2321@1|root,COG2321@2|Bacteria,1ZSN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158397_k127_1888704_0	203119.Cthe_3075	7.789e-178	573.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,249KV@186801|Clostridia,3WGCX@541000|Ruminococcaceae	186801|Clostridia	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158397_k127_1888704_2	1384056.N787_07690	3.331e-39	155.0	COG4339@1|root,COG4339@2|Bacteria,1QV5J@1224|Proteobacteria,1T5PZ@1236|Gammaproteobacteria,1X6K0@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1888704_5	880072.Desac_0840	0.0001057	49.0	292GJ@1|root,2ZQ0S@2|Bacteria,1PAAB@1224|Proteobacteria,432CZ@68525|delta/epsilon subdivisions,2WY0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SRR25158397_k127_1888704_4	880072.Desac_0839	5.284e-30	124.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,42MW1@68525|delta/epsilon subdivisions,2WJBE@28221|Deltaproteobacteria,2MQZ4@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158397_k127_1891459_1	84531.JMTZ01000137_gene1432	2.533e-38	160.0	COG0860@1|root,COG3979@1|root,COG0860@2|Bacteria,COG3979@2|Bacteria,1QVSC@1224|Proteobacteria	1224|Proteobacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1891459_3	579137.Metvu_1510	1.163e-12	80.0	COG3291@1|root,arCOG03991@1|root,arCOG02508@2157|Archaea,arCOG03991@2157|Archaea	2157|Archaea	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM_6,NosD,PKD,PQQ_3
SRR25158397_k127_1891459_0	234267.Acid_5523	2.825e-44	173.0	COG1651@1|root,COG1651@2|Bacteria,3Y87P@57723|Acidobacteria	2|Bacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158397_k127_1891459_2	404589.Anae109_0475	9.471e-32	136.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158397_k127_1892315_2	552811.Dehly_1611	1.449e-138	446.0	COG3943@1|root,COG3943@2|Bacteria,2G9QK@200795|Chloroflexi	200795|Chloroflexi	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
SRR25158397_k127_1892315_9	760192.Halhy_2185	0.0001689	46.0	COG0286@1|root,COG0286@2|Bacteria,4NG0E@976|Bacteroidetes,1ISJM@117747|Sphingobacteriia	976|Bacteroidetes	V	COG0286 Type I restriction-modification system methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR25158397_k127_1892315_6	1038859.AXAU01000018_gene6715	2.256e-16	81.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,2UM3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158397_k127_1892315_8	1304883.KI912532_gene1075	2.978e-05	52.0	COG4772@1|root,COG4772@2|Bacteria,1QVCH@1224|Proteobacteria,2WGQ6@28216|Betaproteobacteria,2KVN0@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_1892315_4	234267.Acid_4315	4.477e-59	227.0	2BF9B@1|root,32926@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR25158397_k127_1892315_0	1415780.JPOG01000001_gene2381	0.0	1318.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,1S05Q@1236|Gammaproteobacteria,1X429@135614|Xanthomonadales	135614|Xanthomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158397_k127_1892315_1	1210884.HG799465_gene11817	6.594e-142	475.0	COG3827@1|root,COG3827@2|Bacteria,2IXVY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1892315_3	234267.Acid_4318	1.703e-103	359.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158397_k127_1892315_7	404589.Anae109_3399	1.004e-07	65.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SRR25158397_k127_1892315_5	886293.Sinac_4968	1.507e-34	151.0	COG1716@1|root,COG1716@2|Bacteria,2IZYG@203682|Planctomycetes	203682|Planctomycetes	C	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SRR25158397_k127_1899002_3	518766.Rmar_1239	6.666e-54	203.0	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes,1FJA7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158397_k127_1899002_0	518766.Rmar_0330	2.103e-200	662.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1FIX1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_1899002_1	404589.Anae109_1185	9.211e-115	385.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
SRR25158397_k127_1899002_2	1121920.AUAU01000013_gene1763	1.249e-104	368.0	COG0515@1|root,COG0515@2|Bacteria	1121920.AUAU01000013_gene1763|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1907493_0	1267535.KB906767_gene1283	3.551e-87	294.0	COG1187@1|root,COG1187@2|Bacteria,3Y6Y9@57723|Acidobacteria,2JP1I@204432|Acidobacteriia	204432|Acidobacteriia	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158397_k127_1907493_1	357808.RoseRS_1405	8.424e-15	83.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158397_k127_1907615_1	498848.TaqDRAFT_5327	1.947e-58	213.0	COG1281@1|root,COG1281@2|Bacteria,1WJ1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRR25158397_k127_1907615_5	986075.CathTA2_1858	6.282e-14	75.0	COG1225@1|root,COG1225@2|Bacteria,1VGP9@1239|Firmicutes,4HQ3V@91061|Bacilli	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158397_k127_1907615_3	1120973.AQXL01000135_gene1319	4.4e-35	136.0	COG1225@1|root,COG1225@2|Bacteria,1V6MU@1239|Firmicutes,4HK8J@91061|Bacilli,27A0F@186823|Alicyclobacillaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158397_k127_1907615_2	485913.Krac_9819	1.514e-51	194.0	2DQBG@1|root,335T7@2|Bacteria,2G96K@200795|Chloroflexi	200795|Chloroflexi	C	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
SRR25158397_k127_1907615_4	1499968.TCA2_5107	2.152e-28	122.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_1907615_6	604354.TSIB_0759	0.0001669	51.0	COG1983@1|root,arCOG03456@2157|Archaea,2XZT2@28890|Euryarchaeota	28890|Euryarchaeota	K	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR25158397_k127_1907615_0	1192034.CAP_6426	4.185e-74	258.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZAP@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158397_k127_1910055_17	493475.GARC_0491	0.0004015	53.0	COG3577@1|root,COG3577@2|Bacteria,1N8CA@1224|Proteobacteria,1SDTC@1236|Gammaproteobacteria,468RZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_19,gag-asp_proteas
SRR25158397_k127_1910055_1	1232410.KI421422_gene2064	9.458e-137	449.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,43RXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158397_k127_1910055_7	767817.Desgi_4305	1.082e-92	315.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,25ZYM@186807|Peptococcaceae	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158397_k127_1910055_11	926549.KI421517_gene1508	1.294e-28	130.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
SRR25158397_k127_1910055_5	861299.J421_4352	1.234e-95	329.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158397_k127_1910055_15	1500281.JQKZ01000029_gene690	9.882e-07	60.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1HZTP@117743|Flavobacteriia,3ZQCQ@59732|Chryseobacterium	976|Bacteroidetes	F	GMP synthase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158397_k127_1910055_0	1166018.FAES_3836	3.96e-151	486.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158397_k127_1910055_3	926566.Terro_2080	8.068e-106	353.0	COG0189@1|root,COG0189@2|Bacteria,3Y37D@57723|Acidobacteria,2JI05@204432|Acidobacteriia	204432|Acidobacteriia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1910055_10	1267534.KB906756_gene390	4.33e-64	229.0	COG4947@1|root,COG4947@2|Bacteria,3Y4B1@57723|Acidobacteria,2JKYT@204432|Acidobacteriia	204432|Acidobacteriia	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158397_k127_1910055_13	309807.SRU_1196	2.351e-19	98.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158397_k127_1910055_8	309807.SRU_1197	3.772e-77	270.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	yxlF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_1910055_9	215803.DB30_2740	6.91e-68	236.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,2YVDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Iron/manganese superoxide dismutases, C-terminal domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158397_k127_1910055_2	1395571.TMS3_0107090	6.24e-109	371.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	sumf2	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158397_k127_1910055_16	306281.AJLK01000073_gene2529	2.42e-05	56.0	296ZB@1|root,2ZU7W@2|Bacteria,1G5TH@1117|Cyanobacteria,1JKSJ@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1910055_4	1173027.Mic7113_2540	7.677e-103	339.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158397_k127_1910055_6	1095769.CAHF01000006_gene1870	1.846e-94	317.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2VKPI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158397_k127_1910055_14	861299.J421_0340	8.126e-13	81.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158397_k127_1910055_12	1123368.AUIS01000005_gene414	2.204e-21	108.0	2E36Z@1|root,32Y6R@2|Bacteria,1NCM6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1921934_1	443143.GM18_0868	1.024e-90	305.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158397_k127_1921934_0	335543.Sfum_2578	5.161e-171	553.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,2MQ65@213462|Syntrophobacterales	28221|Deltaproteobacteria	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158397_k127_1921934_2	204669.Acid345_0720	4.815e-16	81.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRR25158397_k127_1925108_0	338966.Ppro_0432	1.604e-113	374.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRR25158397_k127_1925108_6	1469607.KK073768_gene1058	2.397e-68	243.0	COG4242@1|root,COG4242@2|Bacteria,1G4I0@1117|Cyanobacteria,1HMS8@1161|Nostocales	1117|Cyanobacteria	PQ	Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158397_k127_1925108_2	1047013.AQSP01000123_gene1523	1.249e-96	351.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_1925108_1	278963.ATWD01000001_gene3702	3.219e-104	361.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158397_k127_1925108_5	671143.DAMO_1647	5.939e-72	253.0	COG0673@1|root,COG0673@2|Bacteria,2NNUQ@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA
SRR25158397_k127_1925108_3	1121920.AUAU01000004_gene798	1.322e-78	284.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
SRR25158397_k127_1925108_7	1379270.AUXF01000006_gene300	7.899e-44	172.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
SRR25158397_k127_1925108_4	525897.Dbac_3379	8.894e-75	262.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2M7TA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158397_k127_1925108_10	1122609.AUGT01000018_gene109	1.761e-07	63.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,CHAP,TIG
SRR25158397_k127_1925108_9	768670.Calni_0301	7.212e-15	81.0	COG2825@1|root,COG2825@2|Bacteria,2GFRM@200930|Deferribacteres	200930|Deferribacteres	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158397_k127_1925108_8	903818.KI912268_gene2245	1.511e-28	128.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158397_k127_1934661_8	671143.DAMO_1580	2.878e-21	94.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_1934661_9	1089550.ATTH01000001_gene2130	2.722e-14	80.0	COG4634@1|root,COG4634@2|Bacteria,4NVD2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1934661_3	240015.ACP_1304	8.49e-95	323.0	COG3547@1|root,COG3547@2|Bacteria,3Y52I@57723|Acidobacteria,2JMUS@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158397_k127_1934661_5	1123368.AUIS01000033_gene1370	2.472e-80	284.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria	1224|Proteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158397_k127_1934661_7	1121861.KB899911_gene1355	1.852e-35	142.0	COG1309@1|root,COG1309@2|Bacteria,1RBV0@1224|Proteobacteria,2U7VY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158397_k127_1934661_6	1519464.HY22_07215	1.423e-78	275.0	COG1398@1|root,COG1398@2|Bacteria	2|Bacteria	I	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158397_k127_1934661_2	365044.Pnap_1202	2.973e-182	623.0	COG1404@1|root,COG1404@2|Bacteria,1QVJR@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158397_k127_1934661_1	365044.Pnap_1203	2.888e-205	671.0	COG4249@1|root,COG4249@2|Bacteria,1QWF7@1224|Proteobacteria,2WHK2@28216|Betaproteobacteria,4AJYX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Peptidase_C14
SRR25158397_k127_1934661_0	448385.sce2805	0.0	1330.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158397_k127_1934661_4	448385.sce2804	3.98e-84	293.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158397_k127_1936589_0	404589.Anae109_2021	5.286e-208	669.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YWBK@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158397_k127_1936589_3	1996.JOFO01000003_gene6308	2.542e-54	204.0	COG3291@1|root,COG3291@2|Bacteria,2GKA0@201174|Actinobacteria,4EJAC@85012|Streptosporangiales	201174|Actinobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
SRR25158397_k127_1936589_1	335543.Sfum_1411	7.243e-89	317.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158397_k127_1936589_2	1068978.AMETH_5686	1.449e-70	262.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria,4E2VT@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the peptidase S51 family	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158397_k127_1940300_3	1120953.AUBH01000001_gene914	8.937e-64	233.0	COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_1940300_0	1122603.ATVI01000007_gene1627	1.022e-111	375.0	COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,1X4WM@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_1940300_1	1453501.JELR01000001_gene3146	4.414e-99	330.0	COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,464FN@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter	ycfV	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_1940300_2	1384056.N787_10630	2.383e-88	308.0	COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria,1X3QX@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	ybjY	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158397_k127_1940300_4	1151292.QEW_0209	0.0004705	50.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CW_binding_2,NLPC_P60,SH3_3
SRR25158397_k127_1949025_4	1121272.KB903283_gene5109	1.687e-12	67.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,4DEGR@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_1949025_3	570268.ANBB01000027_gene700	9.417e-29	132.0	COG2227@1|root,COG2227@2|Bacteria,2H167@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_1949025_2	671143.DAMO_2689	4.072e-58	209.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158397_k127_1949025_1	1121918.ARWE01000001_gene292	2.541e-106	363.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,43TSP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158397_k127_1949025_0	706587.Desti_2760	1.931e-116	382.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158397_k127_1951786_1	667014.Thein_1717	4.896e-118	389.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158397_k127_1951786_0	234267.Acid_1490	1.044e-151	503.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158397_k127_1951786_2	215803.DB30_2099	6.59e-31	125.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria,2YVUI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158397_k127_1952357_0	479432.Sros_0370	2.571e-67	234.0	COG1335@1|root,COG1335@2|Bacteria,2I1KX@201174|Actinobacteria,4ENII@85012|Streptosporangiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158397_k127_1952357_1	1196322.A370_00688	5.442e-36	144.0	COG1309@1|root,COG1309@2|Bacteria,1V0AX@1239|Firmicutes,249FG@186801|Clostridia,36HB6@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158397_k127_1952357_3	512565.AMIS_40680	4.728e-10	74.0	COG3507@1|root,COG5492@1|root,COG3507@2|Bacteria,COG5492@2|Bacteria,2GK37@201174|Actinobacteria	201174|Actinobacteria	N	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Big_4,Glyco_hydro_43,Laminin_G_3
SRR25158397_k127_1952357_2	1380390.JIAT01000010_gene4491	3.125e-31	144.0	COG3250@1|root,COG3250@2|Bacteria,2HPPK@201174|Actinobacteria,4CR29@84995|Rubrobacteria	84995|Rubrobacteria	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158397_k127_1952357_4	590998.Celf_1482	4.599e-07	64.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	yxiA	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	GH43_C,Glyco_hydro_43,Laminin_G_3
SRR25158397_k127_1966216_0	204669.Acid345_2747	3.324e-204	655.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria,2JIA9@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158397_k127_1966216_2	1123242.JH636434_gene5196	4.672e-32	141.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidase_6,CarboxypepD_reg,LysM,PD40,Peptidase_M23,Peptidase_M56,SBP_bac_10
SRR25158397_k127_1966216_1	1501230.ET33_37380	2.746e-62	224.0	COG0739@1|root,COG0739@2|Bacteria,1V2IA@1239|Firmicutes,4HG3A@91061|Bacilli,275FJ@186822|Paenibacillaceae	91061|Bacilli	M	Peptidase family M23	yebA5	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158397_k127_198301_0	751944.HALDL1_04560	6.868e-15	78.0	COG1225@1|root,arCOG00310@2157|Archaea,2XWQE@28890|Euryarchaeota,23VT3@183963|Halobacteria	183963|Halobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp1	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158397_k127_198301_1	69395.JQLZ01000003_gene103	6.483e-14	87.0	2DC46@1|root,2ZCU7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_1995350_4	1112212.JH584235_gene279	2.488e-85	305.0	COG1629@1|root,COG4771@2|Bacteria,1PSM0@1224|Proteobacteria,2U3MX@28211|Alphaproteobacteria,2K0HM@204457|Sphingomonadales	204457|Sphingomonadales	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_1995350_0	1300345.LF41_892	1.33e-168	542.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,1RY8M@1236|Gammaproteobacteria,1X3JA@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
SRR25158397_k127_1995350_2	743721.Psesu_1284	5.207e-102	364.0	COG1653@1|root,COG1653@2|Bacteria,1MX59@1224|Proteobacteria,1RZSI@1236|Gammaproteobacteria,1X356@135614|Xanthomonadales	135614|Xanthomonadales	G	ABC transporter substrate-binding protein	malE	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158397_k127_1995350_1	945713.IALB_1188	2.057e-107	355.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	lacF	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158397_k127_1995350_3	1211114.ALIP01000042_gene499	9.291e-101	349.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1S4G6@1236|Gammaproteobacteria,1X3NS@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158397_k127_1995350_5	215803.DB30_8838	7.357e-40	167.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,42Q3U@68525|delta/epsilon subdivisions,2WJ18@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2019298_1	1448860.BBJO01000014_gene1290	1.653e-68	239.0	COG1250@1|root,arCOG00250@2157|Archaea,2XT9S@28890|Euryarchaeota,23TDY@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd3	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158397_k127_2019298_10	1192034.CAP_7790	0.0006468	53.0	COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,438CS@68525|delta/epsilon subdivisions,2WYMI@28221|Deltaproteobacteria,2YWK8@29|Myxococcales	28221|Deltaproteobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.25	ko:K08604	ko05110,ko05111,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PPC,Peptidase_M4,Peptidase_M4_C
SRR25158397_k127_2019298_9	1288494.EBAPG3_1090	3.121e-07	63.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2WESG@28216|Betaproteobacteria,374PV@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Ankyrin repeats (many copies)	-	-	-	ko:K06867,ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_4,Ank_5
SRR25158397_k127_2019298_3	926569.ANT_00800	2.572e-52	201.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
SRR25158397_k127_2019298_8	1267534.KB906759_gene1849	1.591e-11	74.0	COG1729@1|root,COG1729@2|Bacteria,3Y4ME@57723|Acidobacteria,2JJA9@204432|Acidobacteriia	204432|Acidobacteriia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
SRR25158397_k127_2019298_5	1301098.PKB_3070	4.071e-39	161.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Polysaccharide deacetylase	yadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016810,GO:0016814,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158397_k127_2019298_6	1121013.P873_06430	7.895e-18	90.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1X7GX@135614|Xanthomonadales	135614|Xanthomonadales	J	RNA-binding protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
SRR25158397_k127_2019298_0	945713.IALB_1500	8.402e-105	362.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084,ko:K06196	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.2	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
SRR25158397_k127_2019298_7	1289135.A966_08089	1.756e-15	87.0	COG1729@1|root,COG4232@1|root,COG1729@2|Bacteria,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	ko:K01999,ko:K08309	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko01000,ko01011,ko02000	3.A.1.4	GH23	-	Beta-lactamase,OmpA,SLT,TPR_6,Thioredoxin_7
SRR25158397_k127_2019298_4	926569.ANT_04550	2.032e-51	192.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158397_k127_2019298_2	1207058.L53_11565	4.078e-53	200.0	COG3108@1|root,COG3108@2|Bacteria,1RAMQ@1224|Proteobacteria,2UQDA@28211|Alphaproteobacteria,43WJZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRR25158397_k127_2022990_1	575540.Isop_2661	7.744e-228	718.0	COG3387@1|root,COG3387@2|Bacteria,2IXUW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158397_k127_2022990_0	886293.Sinac_7205	1.051e-256	818.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_P460,Glyco_hydro_26,PA14,RsgI_N
SRR25158397_k127_2022990_2	42256.RradSPS_2282	2.156e-40	155.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_2028026_4	1151117.AJLF01000001_gene920	1.178e-06	56.0	COG1633@1|root,arCOG03797@1|root,arCOG01104@2157|Archaea,arCOG03797@2157|Archaea,2Y37B@28890|Euryarchaeota,245EW@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	DUF835,Rubrerythrin
SRR25158397_k127_2028026_1	1527444.ucyna2_00926	1.088e-97	332.0	COG1104@1|root,COG1104@2|Bacteria,1G0D5@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158397_k127_2028026_0	1156919.QWC_11211	1.391e-103	346.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VPW4@28216|Betaproteobacteria,3T8XJ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	4.1.1.46	ko:K07045,ko:K14333	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821	RC00390	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158397_k127_2028026_3	1121124.JNIX01000013_gene1550	3.631e-26	119.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2028026_2	1121033.AUCF01000019_gene3730	3.316e-45	169.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2U7NP@28211|Alphaproteobacteria,2JS9M@204441|Rhodospirillales	204441|Rhodospirillales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158397_k127_2050037_13	401053.AciPR4_3034	0.0003226	51.0	2DRPK@1|root,32URD@2|Bacteria,3Y4UQ@57723|Acidobacteria,2JJGZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2050037_6	204669.Acid345_1999	1.979e-23	105.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria,2JJN5@204432|Acidobacteriia	204432|Acidobacteriia	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158397_k127_2050037_8	1121920.AUAU01000023_gene2434	3.362e-15	89.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria	57723|Acidobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158397_k127_2050037_2	443144.GM21_2999	8.673e-76	283.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,42NBT@68525|delta/epsilon subdivisions,2WKAW@28221|Deltaproteobacteria,43SD0@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	type II and III secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
SRR25158397_k127_2050037_10	498211.CJA_1292	2.974e-07	61.0	COG2374@1|root,COG3391@1|root,COG5184@1|root,COG2374@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	mtsC	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD,Reprolysin_4,SLH,TSP_3
SRR25158397_k127_2050037_12	1232410.KI421421_gene3653	5.411e-05	55.0	2DXN2@1|root,345N1@2|Bacteria,1Q1PJ@1224|Proteobacteria,4319I@68525|delta/epsilon subdivisions,2WWAH@28221|Deltaproteobacteria,43VEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pilus assembly protein, PilO	pulO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR25158397_k127_2050037_11	1382359.JIAL01000001_gene1456	1.877e-05	57.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria,2JJ3Y@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SRR25158397_k127_2050037_9	682795.AciX8_0666	6.672e-08	63.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
SRR25158397_k127_2050037_0	204669.Acid345_1576	1.566e-226	713.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158397_k127_2050037_1	204669.Acid345_1575	9.034e-88	304.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158397_k127_2050037_4	583345.Mmol_0681	1.001e-48	176.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,2KN1B@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
SRR25158397_k127_2050037_3	234267.Acid_2379	1.138e-64	254.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158397_k127_2058649_8	1089548.KI783301_gene1166	4.905e-08	67.0	28N1Z@1|root,2Z9N5@2|Bacteria,1V0S1@1239|Firmicutes,4HCNC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2058649_2	1122915.AUGY01000040_gene615	4.209e-53	215.0	28IBA@1|root,2Z8DT@2|Bacteria,1TRJP@1239|Firmicutes,4HFG9@91061|Bacilli,272DY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2058649_0	1089548.KI783301_gene1163	9.209e-124	432.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,4HBRW@91061|Bacilli,3WF3I@539002|Bacillales incertae sedis	91061|Bacilli	M	Glycosyl transferases group 1	-	-	2.4.1.52	ko:K00712,ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT4	-	DUF3492,Glyco_trans_A_1,Glycos_transf_1
SRR25158397_k127_2058649_7	358681.BBR47_14000	1.756e-09	71.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4HEMZ@91061|Bacilli,26S6X@186822|Paenibacillaceae	91061|Bacilli	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
SRR25158397_k127_2058649_1	1254432.SCE1572_24645	6.801e-66	250.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43DX3@68525|delta/epsilon subdivisions,2X71G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA_3,Pkinase,STAS
SRR25158397_k127_2058649_3	1123368.AUIS01000006_gene566	4.971e-52	207.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
SRR25158397_k127_2058649_4	1463841.JOIR01000006_gene4656	4.084e-43	182.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRR25158397_k127_2058649_6	345341.KUTG_04157	9.793e-13	82.0	COG0726@1|root,COG0726@2|Bacteria,2I3D0@201174|Actinobacteria,4EE27@85010|Pseudonocardiales	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158397_k127_2058649_5	740709.A10D4_05722	8.168e-29	123.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,2QFNW@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	3.1.4.52	ko:K20963	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,EAL,GGDEF
SRR25158397_k127_2059409_2	234267.Acid_3518	9.129e-54	205.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
SRR25158397_k127_2059409_7	448385.sce5956	1.49e-10	72.0	COG1309@1|root,COG1309@2|Bacteria,1RITZ@1224|Proteobacteria,438VB@68525|delta/epsilon subdivisions,2WYC9@28221|Deltaproteobacteria,2Z0YF@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158397_k127_2059409_1	861299.J421_1512	4.422e-124	411.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	cmr	-	2.7.4.9	ko:K00943,ko:K08217,ko:K18833	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.2,2.A.1.21.22	-	-	MFS_1,MFS_3
SRR25158397_k127_2059409_0	886293.Sinac_4912	1.484e-128	438.0	COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes	203682|Planctomycetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158397_k127_2059409_6	1242864.D187_003866	1.287e-10	76.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
SRR25158397_k127_2059409_4	1385515.N791_02140	2.695e-33	140.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria,1X60F@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA mismatch repair protein MutT	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158397_k127_2059409_5	257313.BP1850	3.716e-13	77.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,3T9A1@506|Alcaligenaceae	28216|Betaproteobacteria	S	Ankyrin repeats (3 copies)	arp3	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
SRR25158397_k127_2059409_3	391625.PPSIR1_02286	3.506e-51	199.0	COG1404@1|root,COG1404@2|Bacteria,1PFN6@1224|Proteobacteria,43A1H@68525|delta/epsilon subdivisions,2X26T@28221|Deltaproteobacteria,2Z2JW@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158397_k127_2071210_0	903818.KI912268_gene2181	1.514e-68	263.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_2071210_1	1144342.PMI40_01950	2.502e-23	112.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CarboxypepD_reg,HCBP_related,HemolysinCabind,VWA_2
SRR25158397_k127_2071210_2	234267.Acid_1844	7.607e-17	81.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_2079207_4	257310.BB2743	2.094e-18	92.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2VXKF@28216|Betaproteobacteria,3T4JG@506|Alcaligenaceae	28216|Betaproteobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
SRR25158397_k127_2079207_3	379066.GAU_3713	4.165e-25	109.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
SRR25158397_k127_2079207_2	1254432.SCE1572_19560	9.914e-33	135.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158397_k127_2079207_1	1121438.JNJA01000002_gene3482	7.084e-69	252.0	COG1219@1|root,COG1219@2|Bacteria,1NS53@1224|Proteobacteria,42YDC@68525|delta/epsilon subdivisions,2WU6T@28221|Deltaproteobacteria,2MAA0@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2
SRR25158397_k127_2079207_0	498761.HM1_2174	6.793e-97	325.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158397_k127_2079207_5	449447.MAE_61060	2.623e-09	69.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158397_k127_2080116_20	234267.Acid_3898	7.224e-11	75.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158397_k127_2080116_13	269799.Gmet_1369	2.412e-28	133.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158397_k127_2080116_5	1110697.NCAST_02_00600	3.337e-89	306.0	COG4106@1|root,COG4106@2|Bacteria,2I3QF@201174|Actinobacteria,4G039@85025|Nocardiaceae	201174|Actinobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158397_k127_2080116_6	1385517.N800_02750	9.936e-79	280.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1X954@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158397_k127_2080116_2	269799.Gmet_2577	8.01e-146	469.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158397_k127_2080116_22	497964.CfE428DRAFT_3299	5.295e-08	57.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2080116_17	756067.MicvaDRAFT_1476	2.7e-23	101.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HC3P@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2080116_23	867845.KI911784_gene1314	1.297e-06	57.0	COG1247@1|root,COG1247@2|Bacteria,2G9YI@200795|Chloroflexi,377A3@32061|Chloroflexia	32061|Chloroflexia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158397_k127_2080116_14	945713.IALB_0305	7.185e-28	120.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158397_k127_2080116_19	1123070.KB899260_gene2062	2.313e-14	87.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SRR25158397_k127_2080116_8	927677.ALVU02000001_gene922	7.909e-60	227.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRR25158397_k127_2080116_10	13035.Dacsa_3404	7.878e-47	180.0	COG2258@1|root,COG2258@2|Bacteria,1G6F8@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2080116_16	1279009.ADICEAN_00174	8.831e-24	117.0	COG2259@1|root,COG2259@2|Bacteria,4NVJU@976|Bacteroidetes,47SBK@768503|Cytophagia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158397_k127_2080116_1	722419.PH505_ab00840	2.061e-180	595.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	ERAP1-like C-terminal domain	-	-	3.4.11.14,3.4.11.2	ko:K01256,ko:K01263	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158397_k127_2080116_12	1123242.JH636435_gene2798	9.373e-30	122.0	COG3682@1|root,COG3682@2|Bacteria,2J0FM@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158397_k127_2080116_11	794903.OPIT5_29480	3.788e-44	180.0	COG0526@1|root,COG2373@1|root,COG4219@1|root,COG0526@2|Bacteria,COG2373@2|Bacteria,COG4219@2|Bacteria,46XN8@74201|Verrucomicrobia,3K9XB@414999|Opitutae	414999|Opitutae	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56
SRR25158397_k127_2080116_24	1469607.KK073768_gene1149	0.0001277	49.0	COG4634@1|root,COG4634@2|Bacteria,1G79I@1117|Cyanobacteria,1HPPU@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
SRR25158397_k127_2080116_18	555779.Dthio_PD1503	1.002e-21	96.0	COG2442@1|root,COG2442@2|Bacteria,1N7F9@1224|Proteobacteria,4377G@68525|delta/epsilon subdivisions,2WTB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2080116_0	502025.Hoch_5404	0.0	1165.0	COG1452@1|root,COG1452@2|Bacteria,1QW3G@1224|Proteobacteria,43CZ5@68525|delta/epsilon subdivisions,2X87D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2080116_15	1487953.JMKF01000006_gene5651	9.797e-26	110.0	COG3238@1|root,COG3238@2|Bacteria	2|Bacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158397_k127_2080116_4	1242864.D187_010034	1.197e-109	379.0	COG0531@1|root,COG0531@2|Bacteria,1NRYF@1224|Proteobacteria,43DN8@68525|delta/epsilon subdivisions,2X6GY@28221|Deltaproteobacteria,2Z3B2@29|Myxococcales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158397_k127_2080116_3	215803.DB30_2061	8.648e-133	445.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2
SRR25158397_k127_2080116_9	215803.DB30_5113	2.083e-54	198.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158397_k127_2081564_8	648996.Theam_1424	9.399e-61	211.0	COG0481@1|root,COG0481@2|Bacteria,2G3R9@200783|Aquificae	200783|Aquificae	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158397_k127_2081564_10	378806.STAUR_7589	4.04e-35	138.0	COG1366@1|root,COG1366@2|Bacteria,1NJGJ@1224|Proteobacteria	1224|Proteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158397_k127_2081564_11	378806.STAUR_7590	2.597e-34	140.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
SRR25158397_k127_2081564_13	497964.CfE428DRAFT_1204	4.946e-32	139.0	COG2856@1|root,COG2856@2|Bacteria,46W5X@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2081564_5	316067.Geob_2508	1.954e-90	308.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158397_k127_2081564_25	1122226.AUHX01000007_gene2724	0.0009052	47.0	2APBA@1|root,31EDH@2|Bacteria,4NPIT@976|Bacteroidetes,1I25X@117743|Flavobacteriia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158397_k127_2081564_1	1499967.BAYZ01000184_gene4567	7.93e-236	749.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158397_k127_2081564_6	640081.Dsui_1522	4.064e-70	263.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SRR25158397_k127_2081564_0	1382359.JIAL01000001_gene1070	9.85e-247	769.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158397_k127_2081564_2	743721.Psesu_2230	1.457e-149	511.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales	135614|Xanthomonadales	P	Outer membrane receptor for ferrienterochelin and colicins	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_2081564_17	1254432.SCE1572_45530	7.606e-27	115.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2YVHC@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158397_k127_2081564_14	1499967.BAYZ01000165_gene6645	4.061e-31	125.0	COG0211@1|root,COG0211@2|Bacteria,2NPSU@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158397_k127_2081564_4	289376.THEYE_A0433	5.904e-118	388.0	COG0536@1|root,COG0536@2|Bacteria,3J0E3@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR25158397_k127_2081564_12	1115803.HMPREF1129_0962	2.783e-34	146.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4D331@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158397_k127_2081564_18	661087.HMPREF1008_01380	1.251e-23	109.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CVU7@84998|Coriobacteriia	84998|Coriobacteriia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158397_k127_2081564_7	760568.Desku_2572	3.016e-68	243.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_2081564_16	1232410.KI421412_gene399	4.076e-27	116.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,42S60@68525|delta/epsilon subdivisions,2WRAR@28221|Deltaproteobacteria,43SM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Predicted SPOUT methyltransferase	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158397_k127_2081564_19	204669.Acid345_4135	1.339e-20	95.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria,2JK2N@204432|Acidobacteriia	204432|Acidobacteriia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158397_k127_2081564_23	706587.Desti_2731	3.907e-05	56.0	COG1466@1|root,COG1466@2|Bacteria,1Q2BW@1224|Proteobacteria,437YE@68525|delta/epsilon subdivisions,2X38A@28221|Deltaproteobacteria,2MSDN@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	dna polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	-
SRR25158397_k127_2081564_22	68194.JNXR01000029_gene2237	4.246e-16	91.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria	201174|Actinobacteria	Q	amine oxidase	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid
SRR25158397_k127_2081564_3	1380393.JHVP01000007_gene4485	3.089e-131	458.0	COG2340@1|root,COG4409@1|root,COG2340@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	BNR_2,CBM_35,CW_binding_2,DUF4214,Peptidase_M10
SRR25158397_k127_2081564_15	1267533.KB906735_gene4493	1.62e-29	138.0	COG4932@1|root,COG4932@2|Bacteria,3Y930@57723|Acidobacteria	57723|Acidobacteria	M	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_2081564_21	316274.Haur_4361	1.422e-16	95.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_6,PEGA,Peptidase_S8
SRR25158397_k127_2081564_9	1192034.CAP_3960	2.584e-42	163.0	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,43ACX@68525|delta/epsilon subdivisions,2X5SX@28221|Deltaproteobacteria	1224|Proteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_2081564_24	234267.Acid_4563	0.0003504	43.0	COG0477@1|root,COG2814@2|Bacteria,3Y3ZZ@57723|Acidobacteria	57723|Acidobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_2084654_0	1173027.Mic7113_3556	1.163e-172	558.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1HG9W@1150|Oscillatoriales	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRR25158397_k127_2084654_9	861299.J421_1529	2.208e-36	149.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158397_k127_2084654_11	234267.Acid_0946	2.491e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,3Y85C@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2084654_4	1267535.KB906767_gene3877	4.11e-89	303.0	COG0600@1|root,COG0600@2|Bacteria,3Y5KR@57723|Acidobacteria,2JNDD@204432|Acidobacteriia	204432|Acidobacteriia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158397_k127_2084654_2	1382359.JIAL01000001_gene1326	7.482e-113	373.0	COG1116@1|root,COG1116@2|Bacteria,3Y4J1@57723|Acidobacteria,2JMUR@204432|Acidobacteriia	204432|Acidobacteriia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158397_k127_2084654_5	1382359.JIAL01000001_gene1327	1.852e-82	293.0	COG0600@1|root,COG0600@2|Bacteria,3Y5KR@57723|Acidobacteria,2JNDD@204432|Acidobacteriia	204432|Acidobacteriia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158397_k127_2084654_1	1267535.KB906767_gene3874	2.276e-138	445.0	COG0715@1|root,COG0715@2|Bacteria,3Y5UN@57723|Acidobacteria,2JNY2@204432|Acidobacteriia	204432|Acidobacteriia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158397_k127_2084654_8	1158146.KB907122_gene415	7.139e-48	181.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158397_k127_2084654_3	240016.ABIZ01000001_gene3135	2.036e-105	361.0	COG0714@1|root,COG0714@2|Bacteria,46S9V@74201|Verrucomicrobia,2ITT6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158397_k127_2084654_6	518766.Rmar_2321	5.464e-68	241.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1FIVV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158397_k127_2084654_7	1203611.KB894543_gene1837	1.376e-61	224.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,22UD9@171550|Rikenellaceae	976|Bacteroidetes	S	von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SRR25158397_k127_2084654_10	563031.HMPREF0666_00470	1.689e-28	128.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158397_k127_2084696_10	903818.KI912268_gene3050	8.652e-24	106.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158397_k127_2084696_3	266117.Rxyl_2946	6.684e-96	347.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158397_k127_2084696_2	1487953.JMKF01000072_gene3523	6.048e-120	399.0	COG1819@1|root,COG1819@2|Bacteria,1G1XQ@1117|Cyanobacteria,1H9CT@1150|Oscillatoriales	1117|Cyanobacteria	CG	COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase	crtX	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
SRR25158397_k127_2084696_13	1150469.RSPPHO_00647	2.426e-09	66.0	COG0671@1|root,COG0671@2|Bacteria,1N7CW@1224|Proteobacteria,2TRDP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	phosphoesterase, PA-phosphatase related	lpxE	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158397_k127_2084696_9	240292.Ava_1741	5.77e-28	113.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2442 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2084696_11	1234664.AMRO01000027_gene1215	4.831e-21	103.0	2AFVE@1|root,315XY@2|Bacteria,1V9WC@1239|Firmicutes,4HJ2Y@91061|Bacilli,1WHEF@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2084696_4	309807.SRU_0883	3.179e-87	306.0	COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1FK5M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR25158397_k127_2084696_6	1379270.AUXF01000002_gene1739	1.247e-80	284.0	COG0454@1|root,COG0456@2|Bacteria,1ZTIN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2084696_5	388413.ALPR1_06310	2.978e-84	290.0	COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,47UKI@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158397_k127_2084696_7	404589.Anae109_4379	5.703e-77	270.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YWPQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158397_k127_2084696_1	1356852.N008_14280	4.668e-130	424.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,47MUI@768503|Cytophagia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158397_k127_2084696_0	666685.R2APBS1_1157	6.029e-147	502.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1X334@135614|Xanthomonadales	135614|Xanthomonadales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158397_k127_2084696_8	234267.Acid_7924	6.571e-37	152.0	2BMF1@1|root,32FZM@2|Bacteria,3Y8ZK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2084696_14	1121106.JQKB01000261_gene2707	9.26e-05	49.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2UG54@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158397_k127_2084696_12	1336235.JAEG01000006_gene727	1.633e-16	87.0	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,2TTK7@28211|Alphaproteobacteria,4B8HF@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	MA20_23080	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_2090757_4	1163407.UU7_09310	2.236e-12	72.0	COG0745@1|root,COG2203@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1XDAG@135614|Xanthomonadales	135614|Xanthomonadales	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158397_k127_2090757_3	331869.BAL199_02654	1.648e-60	214.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,4BSEK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
SRR25158397_k127_2090757_1	1502850.FG91_01135	1.23e-81	285.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VFY5@28211|Alphaproteobacteria,2K1MD@204457|Sphingomonadales	204457|Sphingomonadales	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158397_k127_2090757_0	1300345.LF41_2874	9.285e-131	426.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1X3D0@135614|Xanthomonadales	135614|Xanthomonadales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158397_k127_2090757_2	1242864.D187_010427	4.417e-61	226.0	2E458@1|root,32Z1A@2|Bacteria,1PAGT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_209202_1	1121920.AUAU01000023_gene2424	5.776e-51	189.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
SRR25158397_k127_209202_3	243231.GSU0027	3.399e-28	119.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,43UY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
SRR25158397_k127_209202_5	1121920.AUAU01000014_gene2772	1.021e-14	83.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SRR25158397_k127_209202_0	1047013.AQSP01000135_gene1613	4.742e-70	259.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158397_k127_209202_2	319225.Plut_0616	6.172e-31	133.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158397_k127_209202_4	1125863.JAFN01000001_gene3051	2.633e-26	121.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SRR25158397_k127_209202_6	198467.NP92_09625	1.021e-07	57.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,21X4F@150247|Anoxybacillus	91061|Bacilli	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158397_k127_2096314_0	443144.GM21_3357	2.573e-119	397.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158397_k127_2096314_18	1500304.JQKY01000008_gene3104	4.086e-33	138.0	COG0454@1|root,COG0456@2|Bacteria,1PG3T@1224|Proteobacteria,2V3M0@28211|Alphaproteobacteria,4BFHI@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158397_k127_2096314_6	153721.MYP_4398	1.92e-92	317.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR25158397_k127_2096314_21	1304874.JAFY01000005_gene1629	1.126e-10	69.0	2DBZS@1|root,2ZC3A@2|Bacteria	2|Bacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158397_k127_2096314_22	1173020.Cha6605_1333	5.677e-09	66.0	COG0589@1|root,COG0589@2|Bacteria,1G6JK@1117|Cyanobacteria	1117|Cyanobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158397_k127_2096314_19	1121352.JHZP01000004_gene1501	3.467e-15	81.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,2VR7C@28216|Betaproteobacteria,2KR8C@206351|Neisseriales	206351|Neisseriales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
SRR25158397_k127_2096314_20	670487.Ocepr_1908	3.756e-12	71.0	COG0745@1|root,COG0745@2|Bacteria	670487.Ocepr_1908|-	T	phosphorelay signal transduction system	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
SRR25158397_k127_2096314_17	10228.TriadP52874	2.444e-36	141.0	COG3603@1|root,2S7H6@2759|Eukaryota	2759|Eukaryota	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
SRR25158397_k127_2096314_23	1122132.AQYH01000003_gene3085	7.887e-07	56.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VEVS@28211|Alphaproteobacteria,4BMGQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_2096314_14	1173026.Glo7428_3020	1.896e-49	184.0	COG2219@1|root,COG2219@2|Bacteria,1G7G7@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2096314_15	880072.Desac_2694	1.007e-44	177.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MRZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158397_k127_2096314_3	530564.Psta_1105	1.437e-104	347.0	COG0583@1|root,COG0583@2|Bacteria,2J27E@203682|Planctomycetes	203682|Planctomycetes	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158397_k127_2096314_4	448385.sce8039	3.195e-102	340.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2YTTQ@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158397_k127_2096314_2	1121920.AUAU01000004_gene849	2.448e-115	385.0	COG0861@1|root,COG0861@2|Bacteria,3Y37C@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158397_k127_2096314_10	1248916.ANFY01000005_gene2781	9.242e-69	238.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2U7G8@28211|Alphaproteobacteria,2K456@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158397_k127_2096314_24	298386.PBPRB1578	8.697e-06	50.0	2DRWY@1|root,33DG4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2096314_1	246197.MXAN_6138	1.818e-115	372.0	COG0262@1|root,COG0262@2|Bacteria,1QH1Q@1224|Proteobacteria,4341U@68525|delta/epsilon subdivisions,2X4QE@28221|Deltaproteobacteria,2YZE6@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158397_k127_2096314_9	398578.Daci_5074	3.772e-83	301.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158397_k127_2096314_7	1396858.Q666_10270	6.47e-90	304.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158397_k127_2096314_12	1229172.JQFA01000002_gene4501	2.85e-66	243.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G2AT@1117|Cyanobacteria	1117|Cyanobacteria	KT	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158397_k127_2096314_16	760192.Halhy_1744	3.112e-40	164.0	COG0641@1|root,COG0641@2|Bacteria,4NG1N@976|Bacteroidetes,1IUNW@117747|Sphingobacteriia	976|Bacteroidetes	C	Anaerobic sulfatase maturase	atsB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158397_k127_2096314_25	196164.23493799	0.0002141	51.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	dddQ	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2,DMSP_lyase
SRR25158397_k127_2096314_5	663610.JQKO01000025_gene250	2.555e-93	317.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria,3ND0G@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158397_k127_2096314_11	713586.KB900536_gene2448	2.903e-67	243.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,1S7AD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158397_k127_2096314_13	227882.SAV_748	3.265e-56	225.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158397_k127_2096314_8	1047013.AQSP01000123_gene1525	6.167e-87	301.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158397_k127_209738_10	1121468.AUBR01000096_gene781	7.985e-34	137.0	2AII4@1|root,31902@2|Bacteria,1VY3B@1239|Firmicutes,251KQ@186801|Clostridia,42IFA@68295|Thermoanaerobacterales	186801|Clostridia	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_209738_11	1410620.SHLA_51c000430	9.953e-08	61.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,4B973@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
SRR25158397_k127_209738_2	768671.ThimaDRAFT_4003	3.324e-264	826.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,1RYHK@1236|Gammaproteobacteria,1WXMQ@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158397_k127_209738_1	1234364.AMSF01000079_gene1834	2.091e-269	844.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,1X697@135614|Xanthomonadales	135614|Xanthomonadales	P	Alkaline phosphatase	phoD2	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N,TAT_signal
SRR25158397_k127_209738_5	1313421.JHBV01000021_gene4886	3.22e-84	287.0	COG1295@1|root,COG1295@2|Bacteria,4NFG8@976|Bacteroidetes,1IQ97@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158397_k127_209738_8	1405.DJ92_414	1.199e-59	223.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07471,ko:K13652,ko:K19056	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,DinB_2,GyrI-like,HTH_18
SRR25158397_k127_209738_4	994573.T472_0206075	2.58e-116	382.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,24BVW@186801|Clostridia,36GH5@31979|Clostridiaceae	186801|Clostridia	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158397_k127_209738_9	1123248.KB893316_gene4667	3.804e-37	146.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1ITAW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158397_k127_209738_3	743721.Psesu_0567	3.468e-233	748.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RRXB@1236|Gammaproteobacteria,1XDB7@135614|Xanthomonadales	135614|Xanthomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_209738_6	903818.KI912268_gene2181	3.677e-79	297.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_209738_12	745776.DGo_CA0734	3.207e-06	54.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158397_k127_209738_7	757424.Hsero_0080	5.616e-60	220.0	COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,2VR68@28216|Betaproteobacteria	28216|Betaproteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158397_k127_209738_0	757424.Hsero_0079	3.14e-271	844.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VNMX@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
SRR25158397_k127_2100198_2	530564.Psta_4139	4.019e-58	207.0	COG2096@1|root,COG2096@2|Bacteria,2IZZ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158397_k127_2100198_3	404589.Anae109_1476	1.827e-37	161.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_2100198_5	243230.DR_0542	3.835e-23	107.0	COG0584@1|root,COG0584@2|Bacteria,1WK5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158397_k127_2100198_6	649349.Lbys_2700	5.019e-06	51.0	2C95S@1|root,335BQ@2|Bacteria,4NVV0@976|Bacteroidetes,47RV0@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158397_k127_2100198_1	644966.Tmar_2240	3.041e-160	522.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WCEJ@538999|Clostridiales incertae sedis	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158397_k127_2100198_4	585503.HMPREF7545_1966	5.459e-29	123.0	COG0406@1|root,COG0406@2|Bacteria,1VEMH@1239|Firmicutes	1239|Firmicutes	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158397_k127_2100198_0	1267535.KB906767_gene1458	3.985e-182	594.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158397_k127_2103620_7	404589.Anae109_0522	2.75e-25	118.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
SRR25158397_k127_2103620_0	234267.Acid_6926	9.952e-264	822.0	COG0374@1|root,COG0374@2|Bacteria,3Y3C2@57723|Acidobacteria	57723|Acidobacteria	C	nickel-dependent hydrogenase, large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SRR25158397_k127_2103620_2	234267.Acid_6925	3.212e-99	336.0	COG5557@1|root,COG5557@2|Bacteria,3Y6AT@57723|Acidobacteria	57723|Acidobacteria	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2103620_3	234267.Acid_6924	6.66e-97	338.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	hybA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0006066,GO:0006071,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016052,GO:0019400,GO:0019405,GO:0019563,GO:0019588,GO:0019662,GO:0019751,GO:0031224,GO:0031226,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:0071944,GO:1901575,GO:1901615,GO:1901616	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7,TAT_signal
SRR25158397_k127_2103620_1	204669.Acid345_4237	3.055e-148	479.0	COG1740@1|root,COG1740@2|Bacteria,3Y3HS@57723|Acidobacteria,2JJYD@204432|Acidobacteriia	204432|Acidobacteriia	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
SRR25158397_k127_2103620_5	742767.HMPREF9456_02741	1.12e-43	168.0	COG0428@1|root,COG0428@2|Bacteria,4NT7J@976|Bacteroidetes,2FWBB@200643|Bacteroidia,22ZZK@171551|Porphyromonadaceae	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
SRR25158397_k127_2103620_4	1267534.KB906756_gene711	3.676e-50	199.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_2103620_10	879212.DespoDRAFT_01311	2.513e-18	94.0	COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,42U5P@68525|delta/epsilon subdivisions,2X27Q@28221|Deltaproteobacteria,2MNRI@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SRR25158397_k127_2103620_8	1089550.ATTH01000001_gene1052	2.109e-24	114.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FJR9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158397_k127_2103620_6	880072.Desac_0008	1.871e-31	128.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MS9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158397_k127_2103620_9	1229172.JQFA01000005_gene185	5.535e-20	100.0	COG3769@1|root,COG3769@2|Bacteria,1G4FD@1117|Cyanobacteria,1H8XX@1150|Oscillatoriales	1117|Cyanobacteria	S	Mannosyl-3-phosphoglycerate phosphatase family	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158397_k127_210825_2	710111.FraQA3DRAFT_4760	4.159e-129	431.0	COG1231@1|root,COG1231@2|Bacteria,2GMV0@201174|Actinobacteria	201174|Actinobacteria	E	amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158397_k127_210825_4	661478.OP10G_2515	1.072e-20	96.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	ytrA	-	-	ko:K07978,ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158397_k127_210825_3	1123242.JH636435_gene1286	6.337e-46	177.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_210825_1	1550073.JROH01000003_gene2460	3.164e-151	484.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,2U2ZW@28211|Alphaproteobacteria,2K0PE@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_210825_0	1550073.JROH01000003_gene2459	4.072e-301	970.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1PTWJ@1224|Proteobacteria,2U237@28211|Alphaproteobacteria,2K176@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,Peptidase_M1
SRR25158397_k127_2115737_7	661478.OP10G_0362	6.543e-08	57.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,DUF4185
SRR25158397_k127_2115737_3	497964.CfE428DRAFT_5420	2.244e-43	183.0	2DM58@1|root,31S4C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2115737_2	1121920.AUAU01000004_gene710	2.268e-96	319.0	COG2057@1|root,COG2057@2|Bacteria,3Y3EC@57723|Acidobacteria	57723|Acidobacteria	I	Coenzyme A transferase	-	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158397_k127_2115737_1	1120972.AUMH01000003_gene2985	3.63e-105	346.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,279JQ@186823|Alicyclobacillaceae	91061|Bacilli	I	Coenzyme A transferase	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158397_k127_2115737_4	1313172.YM304_04440	1.023e-21	102.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158397_k127_2115737_6	446466.Cfla_0426	1.435e-11	66.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158397_k127_2115737_0	1121918.ARWE01000001_gene385	2.657e-211	667.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158397_k127_2120962_0	1382359.JIAL01000001_gene2923	3.716e-115	376.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158397_k127_2120962_7	290633.GOX0387	8.382e-39	148.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2JSU1@204441|Rhodospirillales	204441|Rhodospirillales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158397_k127_2120962_8	903818.KI912268_gene2415	2.089e-35	141.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria	57723|Acidobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158397_k127_2120962_1	1121920.AUAU01000017_gene1254	5.052e-97	323.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158397_k127_2120962_5	316067.Geob_3636	2.201e-65	225.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2WNAH@28221|Deltaproteobacteria,43UTJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158397_k127_2120962_4	1125863.JAFN01000001_gene1826	4.265e-67	233.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158397_k127_2120962_12	1150626.PHAMO_320002	3.922e-08	61.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2JTWP@204441|Rhodospirillales	204441|Rhodospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158397_k127_2120962_9	768670.Calni_1535	9.444e-17	81.0	COG0267@1|root,COG0267@2|Bacteria,2GFZW@200930|Deferribacteres	200930|Deferribacteres	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158397_k127_2120962_11	1121447.JONL01000001_gene735	9.4e-10	62.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2120962_10	1297742.A176_04476	6.15e-11	77.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_2120962_2	1009370.ALO_16252	7.817e-84	295.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4H3CE@909932|Negativicutes	909932|Negativicutes	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
SRR25158397_k127_2120962_6	266117.Rxyl_2172	7.379e-54	198.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158397_k127_2120962_3	471852.Tcur_0288	1.193e-79	273.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4EHA4@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158397_k127_2121081_0	414684.RC1_2702	0.0	1037.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2JPCA@204441|Rhodospirillales	204441|Rhodospirillales	E	NAD-specific glutamate dehydrogenase	gdhA	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158397_k127_2121081_2	351160.RCIX211	8.147e-13	81.0	COG1807@1|root,arCOG03981@1|root,arCOG00566@2157|Archaea,arCOG03981@2157|Archaea,2Y4H0@28890|Euryarchaeota	28890|Euryarchaeota	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_2121081_1	1004785.AMBLS11_05865	6.665e-123	408.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,465IT@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities	fadJ	GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c26730,iETEC_1333.ETEC_2476,iEcE24377_1341.EcE24377A_2637,ic_1306.c2886	3HCDH,3HCDH_N,ECH_1
SRR25158397_k127_2122263_6	926556.Echvi_2165	2.787e-47	189.0	COG1409@1|root,COG5492@1|root,COG1409@2|Bacteria,COG5492@2|Bacteria,4NHMV@976|Bacteroidetes,47UBQ@768503|Cytophagia	976|Bacteroidetes	N	Polysaccharide lyase family 8, N terminal alpha-helical domain	cslA	-	4.2.2.5	ko:K19049	-	-	-	-	ko00000,ko01000	-	PL8	-	DUF1573,Lyase_8,Lyase_8_C,Lyase_8_N
SRR25158397_k127_2122263_8	243231.GSU1905	9.532e-25	105.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158397_k127_2122263_9	1047013.AQSP01000071_gene1936	1.662e-14	86.0	COG0526@1|root,COG0526@2|Bacteria,2NRB8@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_9
SRR25158397_k127_2122263_1	1144275.COCOR_03309	2.439e-114	396.0	COG1305@1|root,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SRR25158397_k127_2122263_5	502025.Hoch_2465	8.56e-82	284.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158397_k127_2122263_7	1121920.AUAU01000004_gene894	4.663e-34	145.0	COG0824@1|root,COG0824@2|Bacteria,3Y8D7@57723|Acidobacteria	57723|Acidobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
SRR25158397_k127_2122263_3	290397.Adeh_0402	6.803e-99	328.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42S2Z@68525|delta/epsilon subdivisions,2X5JB@28221|Deltaproteobacteria,2Z35Y@29|Myxococcales	28221|Deltaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158397_k127_2122263_4	441620.Mpop_3532	1.004e-83	295.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2U0DX@28211|Alphaproteobacteria,1JU37@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_2122263_2	1499967.BAYZ01000017_gene6221	7.042e-112	379.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SRR25158397_k127_2122263_0	396588.Tgr7_2421	1.798e-160	516.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales	135613|Chromatiales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158397_k127_2130580_4	404589.Anae109_1680	0.0009807	51.0	COG0823@1|root,COG3266@1|root,COG4447@1|root,COG5640@1|root,COG0823@2|Bacteria,COG3266@2|Bacteria,COG4447@2|Bacteria,COG5640@2|Bacteria,1QZXX@1224|Proteobacteria	1224|Proteobacteria	U	endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2130580_0	386415.NT01CX_1498	1.118e-97	327.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,36E47@31979|Clostridiaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158397_k127_2130580_1	768671.ThimaDRAFT_1652	2.676e-61	224.0	COG4861@1|root,COG4861@2|Bacteria,1RFGZ@1224|Proteobacteria,1S42X@1236|Gammaproteobacteria,1X0X9@135613|Chromatiales	135613|Chromatiales	S	Transcriptional regulator, AbiEi antitoxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2
SRR25158397_k127_2130580_2	525897.Dbac_0495	9.79e-37	151.0	COG4849@1|root,COG4849@2|Bacteria,1N4EJ@1224|Proteobacteria,430MP@68525|delta/epsilon subdivisions,2WVZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158397_k127_2130580_3	1267535.KB906767_gene1695	2.244e-13	70.0	COG0745@1|root,COG0745@2|Bacteria,3Y4GX@57723|Acidobacteria,2JJ6P@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_213432_2	1454010.JEOE01000014_gene1411	1.529e-05	59.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	CarboxypepD_reg,Glyco_hydro_53,SLH
SRR25158397_k127_213432_1	1144275.COCOR_02106	5.612e-06	60.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K13735,ko:K18491,ko:K20276	ko02024,ko04550,ko05100,map02024,map04550,map05100	-	-	-	ko00000,ko00001,ko03000	-	-	-	CarboxypepD_reg,PDZ_2
SRR25158397_k127_213432_0	331869.BAL199_30392	8.713e-08	57.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2TTXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158397_k127_213432_3	1440052.EAKF1_ch1105c	0.0004132	44.0	COG2207@1|root,COG2207@2|Bacteria,1PF5X@1224|Proteobacteria,1S0K6@1236|Gammaproteobacteria,3XN8T@561|Escherichia	1236|Gammaproteobacteria	K	Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression	ykgD	GO:0001130,GO:0001216,GO:0003674,GO:0003700,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090347,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K18991,ko:K21746	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	Cupin_6,HTH_18
SRR25158397_k127_2137601_1	28258.KP05_12855	1.37e-169	550.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales	135619|Oceanospirillales	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158397_k127_2137601_5	981384.AEYW01000013_gene517	3.088e-09	64.0	2EH77@1|root,33AZ1@2|Bacteria,1NMNZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2137601_0	1121920.AUAU01000010_gene50	9.509e-170	545.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158397_k127_2137601_3	266117.Rxyl_2556	1.058e-114	381.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria,4CT9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Helix-turn-helix domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRR25158397_k127_2137601_2	316274.Haur_4146	4.553e-127	416.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi,3776D@32061|Chloroflexia	32061|Chloroflexia	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158397_k127_2137601_4	1173027.Mic7113_4163	1.289e-14	79.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1FZXP@1117|Cyanobacteria,1H9FJ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
SRR25158397_k127_2151532_0	269799.Gmet_2983	2.06e-105	363.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43TIJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158397_k127_2151532_2	867845.KI911784_gene1282	2.822e-16	85.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77,2.8.1.12,4.6.1.17	ko:K03636,ko:K03637,ko:K03752,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372,R11581	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	ThiS
SRR25158397_k127_2151532_1	1382306.JNIM01000001_gene1158	9.38e-35	138.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158397_k127_2151532_3	1380390.JIAT01000011_gene2661	2.896e-12	75.0	COG1051@1|root,COG1051@2|Bacteria,2HQ01@201174|Actinobacteria,4CRFN@84995|Rubrobacteria	84995|Rubrobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158397_k127_2158364_2	29850.GGTG_03335T0	5.367e-06	48.0	2CUIY@1|root,2RMP7@2759|Eukaryota,38RCF@33154|Opisthokonta,3PT59@4751|Fungi,3RJEI@4890|Ascomycota,21II6@147550|Sordariomycetes,41RDU@639021|Magnaporthales	4751|Fungi	S	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158397_k127_2158364_0	234267.Acid_3115	3.643e-50	205.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria	57723|Acidobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
SRR25158397_k127_2158364_1	211114.JOEF01000001_gene7178	3.781e-39	169.0	COG4188@1|root,COG4188@2|Bacteria,2I3KQ@201174|Actinobacteria,4DZZ4@85010|Pseudonocardiales	201174|Actinobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,Chlorophyllase2
SRR25158397_k127_2180722_4	357808.RoseRS_4060	2.952e-29	136.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_2180722_0	1487953.JMKF01000004_gene648	1.015e-149	486.0	COG0535@1|root,COG0535@2|Bacteria,1G18X@1117|Cyanobacteria,1HEMR@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
SRR25158397_k127_2180722_2	1487953.JMKF01000004_gene647	2.038e-45	166.0	COG0599@1|root,COG0599@2|Bacteria,1G8UR@1117|Cyanobacteria	1117|Cyanobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158397_k127_2180722_3	933262.AXAM01000028_gene3333	3.339e-40	155.0	COG1487@1|root,COG1487@2|Bacteria,1N6FP@1224|Proteobacteria,43BEZ@68525|delta/epsilon subdivisions,2X6TF@28221|Deltaproteobacteria,2MPIF@213118|Desulfobacterales	1224|Proteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_2180722_5	395961.Cyan7425_0156	1.634e-09	68.0	2EE0Y@1|root,337VR@2|Bacteria,1G9ZJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158397_k127_2180722_1	1237149.C900_02615	1.396e-59	209.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_2185678_2	1123073.KB899242_gene1384	5.423e-41	160.0	COG0454@1|root,COG0456@2|Bacteria,1RDH4@1224|Proteobacteria,1SCMT@1236|Gammaproteobacteria,1X66P@135614|Xanthomonadales	135614|Xanthomonadales	K	acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158397_k127_2185678_4	1356852.N008_20540	5.108e-23	105.0	2DTU1@1|root,33MMF@2|Bacteria,4NWD8@976|Bacteroidetes,47SX0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2185678_1	1267535.KB906767_gene3330	3.965e-41	160.0	COG1595@1|root,COG1595@2|Bacteria,3Y5BF@57723|Acidobacteria,2JJZZ@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_2185678_7	1267535.KB906767_gene3331	2.044e-10	71.0	2ERSC@1|root,33JBJ@2|Bacteria,3Y5XV@57723|Acidobacteria,2JK5S@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2185678_3	1267535.KB906767_gene3332	1.121e-32	138.0	2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria,2JJU7@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
SRR25158397_k127_2185678_8	1267535.KB906767_gene3333	8.055e-10	66.0	2EGKM@1|root,33ACV@2|Bacteria,3Y5U1@57723|Acidobacteria,2JK61@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2185678_0	518766.Rmar_0143	8.92e-50	192.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1FIVJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158397_k127_2185678_6	575540.Isop_1921	4.391e-18	90.0	COG0399@1|root,COG0399@2|Bacteria,2J55P@203682|Planctomycetes	203682|Planctomycetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158397_k127_2185678_5	671143.DAMO_1580	1.041e-19	90.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2185678_9	357808.RoseRS_0654	1.078e-06	52.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2187924_3	648757.Rvan_3115	6.75e-55	201.0	COG0438@1|root,COG0438@2|Bacteria,1MWEM@1224|Proteobacteria,2U1NW@28211|Alphaproteobacteria,3N8RC@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_2187924_2	1205680.CAKO01000003_gene3682	7.288e-61	228.0	COG0463@1|root,COG0463@2|Bacteria,1R6A0@1224|Proteobacteria,2TVNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_2187924_0	1123368.AUIS01000027_gene1355	1.128e-246	775.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158397_k127_2187924_1	243233.MCA1168	3.665e-101	341.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,1RS9J@1236|Gammaproteobacteria,1XFU5@135618|Methylococcales	135618|Methylococcales	H	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158397_k127_2221896_6	502025.Hoch_6585	1.035e-19	100.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria,2YVGE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158397_k127_2221896_5	204669.Acid345_2146	4.517e-27	128.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
SRR25158397_k127_2221896_3	1278073.MYSTI_04859	9.797e-82	279.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
SRR25158397_k127_2221896_4	754436.JCM19237_6394	8.945e-65	232.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1Y26K@135623|Vibrionales	135623|Vibrionales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158397_k127_2221896_1	1111479.AXAR01000009_gene2485	8.162e-129	436.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158397_k127_2221896_0	861299.J421_1737	8.563e-167	536.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
SRR25158397_k127_2221896_2	234267.Acid_1567	3.716e-87	302.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158397_k127_2221896_7	743299.Acife_1535	1.144e-13	77.0	COG1487@1|root,COG1487@2|Bacteria,1QG6Z@1224|Proteobacteria,1SFI1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_2225001_9	883156.HMPREF9282_01456	6.114e-09	67.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,4H4VM@909932|Negativicutes	909932|Negativicutes	EG	membrane	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_2225001_3	1237149.C900_00783	3.086e-45	168.0	COG0454@1|root,COG0456@2|Bacteria,4NT3M@976|Bacteroidetes,47VFK@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158397_k127_2225001_0	518766.Rmar_0040	3.726e-101	336.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes	976|Bacteroidetes	J	Pfam Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158397_k127_2225001_2	1144275.COCOR_02487	3.891e-70	251.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158397_k127_2225001_6	234267.Acid_0996	2.287e-21	101.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,TehB
SRR25158397_k127_2225001_8	215803.DB30_5907	1.55e-12	69.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158397_k127_2225001_4	215803.DB30_5907	4.479e-25	107.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158397_k127_2225001_5	883.DvMF_0755	9.207e-22	98.0	2E8MC@1|root,332YU@2|Bacteria,1N7S4@1224|Proteobacteria,4325D@68525|delta/epsilon subdivisions,2WXJA@28221|Deltaproteobacteria,2MFPH@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2225001_1	1121920.AUAU01000004_gene664	2.704e-89	308.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158397_k127_2225001_7	1298863.AUEP01000003_gene3084	1.564e-17	85.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DN19@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_224234_0	1163407.UU7_04752	7.149e-210	674.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,1RPC7@1236|Gammaproteobacteria,1X51W@135614|Xanthomonadales	135614|Xanthomonadales	M	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158397_k127_224234_2	1163407.UU7_14910	1.774e-63	231.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_224234_3	1144275.COCOR_02285	2.614e-52	204.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	yehT	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_224234_1	404589.Anae109_0474	1.124e-75	262.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158397_k127_224245_1	864702.OsccyDRAFT_2545	1.034e-86	308.0	COG0004@1|root,COG0642@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HHZA@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158397_k127_224245_0	886293.Sinac_5965	9.463e-117	391.0	COG0526@1|root,COG2010@1|root,COG0526@2|Bacteria,COG2010@2|Bacteria,2IWVQ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C
SRR25158397_k127_224245_2	1123248.KB893327_gene727	1.246e-07	53.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158397_k127_2256614_3	215803.DB30_1673	3.558e-80	296.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,430R6@68525|delta/epsilon subdivisions,2WVZ1@28221|Deltaproteobacteria,2YYVC@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9
SRR25158397_k127_2256614_4	1122604.JONR01000020_gene467	3.593e-78	273.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1X4SX@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158397_k127_2256614_16	110662.Syncc9605_1244	2.71e-05	53.0	COG1547@1|root,COG1547@2|Bacteria,1G7QG@1117|Cyanobacteria,1H1FQ@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158397_k127_2256614_12	1443125.Z962_10345	4.91e-12	73.0	COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,248PN@186801|Clostridia,36DR9@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_2256614_11	1156937.MFUM_110010	1.551e-26	121.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
SRR25158397_k127_2256614_9	935261.JAGL01000041_gene2598	3.093e-32	138.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,43HKG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158397_k127_2256614_10	1540221.JQNI01000004_gene124	2.667e-29	123.0	COG1246@1|root,COG1246@2|Bacteria,1WMRV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158397_k127_2256614_5	861299.J421_5582	8.062e-73	256.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158397_k127_2256614_7	1157490.EL26_14240	4.635e-64	235.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,4HDJT@91061|Bacilli,279A9@186823|Alicyclobacillaceae	91061|Bacilli	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158397_k127_2256614_1	497964.CfE428DRAFT_2205	1.557e-111	395.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,46SRA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_2256614_14	521674.Plim_0071	1.099e-08	67.0	COG0170@1|root,COG0170@2|Bacteria,2J1H5@203682|Planctomycetes	203682|Planctomycetes	I	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2256614_8	1147.D082_21950	4.455e-36	153.0	COG1836@1|root,COG1836@2|Bacteria,1G07R@1117|Cyanobacteria,1H54D@1142|Synechocystis	1117|Cyanobacteria	S	Integral membrane protein DUF92	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
SRR25158397_k127_2256614_13	706587.Desti_2204	4.623e-10	71.0	2ABP6@1|root,31153@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2256614_15	269798.CHU_1856	1.88e-07	63.0	2A19Z@1|root,30PGH@2|Bacteria,4PC2K@976|Bacteroidetes,47WQC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2256614_0	997346.HMPREF9374_0445	2.991e-120	400.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,27BMY@186824|Thermoactinomycetaceae	91061|Bacilli	S	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158397_k127_2256614_2	502025.Hoch_0166	3.86e-108	355.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158397_k127_2263009_0	587753.EY04_29705	3.476e-149	482.0	COG0671@1|root,COG2453@1|root,COG0671@2|Bacteria,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,1RQAC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IT	Phosphatase	ynbD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	DAGK_cat,DSPc,PAP2_3
SRR25158397_k127_2263009_1	927677.ALVU02000001_gene4017	1.386e-58	218.0	COG4589@1|root,COG4589@2|Bacteria,1GCQF@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158397_k127_2263009_2	1054213.HMPREF9946_00676	1.724e-48	194.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51,6.2.1.3	ko:K00655,ko:K01897	ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00089	R01280,R02241,R09381	RC00004,RC00014,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158397_k127_2263009_4	870187.Thini_2230	1.248e-05	50.0	2DSE5@1|root,33FS0@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
SRR25158397_k127_2263009_3	1173024.KI912149_gene5707	1.024e-33	134.0	COG4113@1|root,COG4113@2|Bacteria,1GDRC@1117|Cyanobacteria,1JMJ1@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_2263016_6	497964.CfE428DRAFT_1447	3.365e-64	243.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158397_k127_2263016_3	378806.STAUR_3955	1.193e-126	428.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158397_k127_2263016_5	1085623.GNIT_3572	1.994e-71	274.0	COG1404@1|root,COG5183@1|root,COG1404@2|Bacteria,COG5183@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,46BFY@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8,SLH
SRR25158397_k127_2263016_8	383372.Rcas_0814	1.8e-36	148.0	294HY@1|root,2ZRXK@2|Bacteria,2GAIJ@200795|Chloroflexi,376D9@32061|Chloroflexia	32061|Chloroflexia	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158397_k127_2263016_2	861299.J421_0743	1.872e-132	440.0	COG4623@1|root,COG4623@2|Bacteria	2|Bacteria	M	carbon-oxygen lyase activity, acting on polysaccharides	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
SRR25158397_k127_2263016_11	1064537.AGSO01000001_gene812	3.124e-29	126.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4FBMZ@85020|Dermabacteraceae	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_2263016_13	497965.Cyan7822_1092	5.058e-11	66.0	COG4634@1|root,COG4634@2|Bacteria,1G71Y@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2263016_12	118168.MC7420_1664	2.114e-24	106.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HC3P@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2263016_0	1242864.D187_006166	4.511e-269	841.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YWG3@29|Myxococcales	28221|Deltaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158397_k127_2263016_1	404589.Anae109_4112	6.625e-135	446.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
SRR25158397_k127_2263016_9	535289.Dtpsy_1880	1.269e-35	155.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,4AEKN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
SRR25158397_k127_2263016_4	237368.SCABRO_01822	1.634e-109	374.0	COG1249@1|root,COG1249@2|Bacteria,2IYD2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158397_k127_2263016_10	580327.Tthe_0532	1.567e-35	139.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,42GHI@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158397_k127_2263016_7	1144275.COCOR_02951	2.595e-52	205.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SRR25158397_k127_2273181_2	485918.Cpin_6477	7.027e-50	186.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
SRR25158397_k127_2273181_8	1227349.C170_03603	0.0003941	54.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase family 6	guxA	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
SRR25158397_k127_2273181_7	177416.FTT_0888c	0.0001459	51.0	COG4969@1|root,COG4969@2|Bacteria,1NG9T@1224|Proteobacteria,1SHYX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilin (bacterial filament)	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
SRR25158397_k127_2273181_3	204669.Acid345_1590	4.554e-33	149.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07708	ko02020,map02020	M00497,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,RsbRD_N
SRR25158397_k127_2273181_0	243231.GSU2043	1.154e-59	215.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158397_k127_2273181_5	483219.LILAB_01505	1.308e-20	96.0	COG0848@1|root,COG0848@2|Bacteria,1Q1RQ@1224|Proteobacteria,437EZ@68525|delta/epsilon subdivisions,2X2MA@28221|Deltaproteobacteria,2Z03D@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158397_k127_2273181_4	246197.MXAN_1447	4.527e-23	104.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,42RJ1@68525|delta/epsilon subdivisions,2X6VG@28221|Deltaproteobacteria,2YVC5@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158397_k127_2273181_1	234267.Acid_1281	1.632e-58	211.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR25158397_k127_2273181_6	234267.Acid_1287	5.675e-20	101.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_2278582_14	1499967.BAYZ01000091_gene3428	1.364e-34	150.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
SRR25158397_k127_2278582_0	398767.Glov_1909	5.012e-210	667.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158397_k127_2278582_15	404589.Anae109_0486	2.137e-30	140.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transglycosylase	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
SRR25158397_k127_2278582_2	682795.AciX8_1432	7.759e-120	406.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_2278582_7	1191523.MROS_1703	4.634e-67	241.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158397_k127_2278582_13	518766.Rmar_0669	1.907e-39	166.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
SRR25158397_k127_2278582_12	1122917.KB899659_gene5839	2.171e-40	159.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HGZ2@91061|Bacilli,26SJY@186822|Paenibacillaceae	91061|Bacilli	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158397_k127_2278582_8	316067.Geob_0373	5.039e-57	228.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SRR25158397_k127_2278582_1	1379698.RBG1_1C00001G0607	3.634e-167	551.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158397_k127_2278582_11	1280390.CBQR020000166_gene4410	8.444e-43	166.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,26WV5@186822|Paenibacillaceae	91061|Bacilli	G	Aldolase	kdgA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158397_k127_2278582_6	1267533.KB906737_gene1605	1.351e-70	267.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158397_k127_2278582_4	234267.Acid_1043	1.297e-94	321.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158397_k127_2278582_10	1242864.D187_006089	9.111e-49	182.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158397_k127_2278582_5	903818.KI912268_gene1552	4.869e-73	272.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158397_k127_2278582_3	292459.STH512	4.658e-101	341.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158397_k127_2278582_9	1173024.KI912151_gene2402	1.214e-54	204.0	COG0823@1|root,COG0823@2|Bacteria,1G28F@1117|Cyanobacteria,1JKQG@1189|Stigonemataceae	1117|Cyanobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2306205_4	1123236.KB899376_gene508	0.0002377	46.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,467FY@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158397_k127_2306205_5	1416752.AYME01000001_gene429	0.0002798	53.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,2GKS8@201174|Actinobacteria,4FQXB@85023|Microbacteriaceae	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2306205_0	1242864.D187_001446	3.925e-79	295.0	COG0642@1|root,COG2202@1|root,COG5000@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,4372J@68525|delta/epsilon subdivisions,2X1U4@28221|Deltaproteobacteria,2YZ0W@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,Response_reg
SRR25158397_k127_2306205_2	179408.Osc7112_3205	4.283e-13	83.0	COG2931@1|root,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria	1117|Cyanobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
SRR25158397_k127_2306205_1	1331660.L313_0780	1.314e-16	94.0	2DVAX@1|root,33V2W@2|Bacteria,1R2KJ@1224|Proteobacteria,1T5S7@1236|Gammaproteobacteria,3NTUA@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2311989_1	886293.Sinac_6796	4.003e-41	165.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158397_k127_2311989_0	1122223.KB890692_gene3023	6.847e-168	534.0	COG1899@1|root,COG1899@2|Bacteria,1WI9Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158397_k127_2319927_2	500153.JOEK01000001_gene4030	5.518e-63	226.0	COG1252@1|root,COG1252@2|Bacteria,2GKC0@201174|Actinobacteria	201174|Actinobacteria	C	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158397_k127_2319927_1	485913.Krac_12604	9.532e-75	267.0	COG1595@1|root,COG1595@2|Bacteria,2G7NX@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_2319927_5	1320556.AVBP01000014_gene1089	1.506e-15	82.0	COG0802@1|root,COG3178@1|root,COG0802@2|Bacteria,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,43ITI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	MA20_24090	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,TsaE
SRR25158397_k127_2319927_0	671143.DAMO_1556	8.55e-111	377.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158397_k127_2319927_3	1122176.KB903532_gene2581	2.404e-31	131.0	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,1ISU2@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SRR25158397_k127_2319927_4	207559.Dde_2703	1.065e-26	124.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2MBRR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158397_k127_2321780_1	926560.KE387027_gene710	3.225e-15	82.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1WN7H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KP	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
SRR25158397_k127_2321780_2	402777.KB235904_gene3713	5.393e-09	64.0	COG0607@1|root,COG0607@2|Bacteria,1G896@1117|Cyanobacteria,1HC6D@1150|Oscillatoriales	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158397_k127_2321780_0	251221.35214309	6.073e-76	275.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
SRR25158397_k127_2367909_3	215803.DB30_1825	1.654e-114	408.0	COG0840@1|root,COG4166@1|root,COG0840@2|Bacteria,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,43BXR@68525|delta/epsilon subdivisions,2X1YS@28221|Deltaproteobacteria,2YYSK@29|Myxococcales	28221|Deltaproteobacteria	ENT	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,SBP_bac_5
SRR25158397_k127_2367909_7	313606.M23134_05224	6.287e-31	132.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_2367909_8	234267.Acid_7247	5.284e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,3Y815@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_2367909_13	639030.JHVA01000001_gene3439	2.327e-12	77.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
SRR25158397_k127_2367909_10	1532558.JL39_22805	1.566e-26	122.0	COG3842@1|root,COG3842@2|Bacteria,1MUP3@1224|Proteobacteria,2TQQ3@28211|Alphaproteobacteria,4B8H8@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158397_k127_2367909_11	1114970.PSF113_2940	9.958e-18	91.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1YNMI@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158397_k127_2367909_16	929703.KE386491_gene628	1.174e-05	56.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,47M60@768503|Cytophagia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158397_k127_2367909_4	913865.DOT_1324	3.391e-52	195.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158397_k127_2367909_5	696281.Desru_2619	2.179e-48	188.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,24ANY@186801|Clostridia,26317@186807|Peptococcaceae	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158397_k127_2367909_6	1254432.SCE1572_34560	5.475e-32	138.0	COG3591@1|root,COG3591@2|Bacteria,1PWC4@1224|Proteobacteria,43E0R@68525|delta/epsilon subdivisions,2WZD0@28221|Deltaproteobacteria,2Z1VE@29|Myxococcales	28221|Deltaproteobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158397_k127_2367909_14	886293.Sinac_4777	7.24e-10	63.0	COG1396@1|root,COG1396@2|Bacteria,2J17Z@203682|Planctomycetes	203682|Planctomycetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
SRR25158397_k127_2367909_9	314230.DSM3645_24877	9.502e-28	116.0	2EDA6@1|root,3376M@2|Bacteria,2J0KG@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2367909_1	215803.DB30_2967	4.736e-140	453.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SRR25158397_k127_2367909_2	366602.Caul_0107	3.793e-119	405.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_2367909_0	450851.PHZ_c3416	4.763e-149	484.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_2367909_15	1234364.AMSF01000088_gene2781	4.959e-09	64.0	COG1196@1|root,COG4219@1|root,COG1196@2|Bacteria,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria,1T2HB@1236|Gammaproteobacteria,1X552@135614|Xanthomonadales	135614|Xanthomonadales	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158397_k127_2367909_12	1340493.JNIF01000003_gene2325	1.593e-17	83.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	macB_1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_23695_3	118168.MC7420_7150	5.262e-62	225.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_tranf_2_4,Glycos_transf_2,RGP
SRR25158397_k127_23695_0	243231.GSU1505	4.528e-99	351.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,43T6N@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	ABC transporter	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158397_k127_23695_1	1469607.KK073768_gene2387	1.018e-94	333.0	COG1682@1|root,COG1682@2|Bacteria,1G23R@1117|Cyanobacteria,1HJJQ@1161|Nostocales	1117|Cyanobacteria	U	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158397_k127_23695_4	481448.Minf_0544	5.464e-28	123.0	COG2242@1|root,COG2242@2|Bacteria,46T8W@74201|Verrucomicrobia,37GWK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158397_k127_23695_2	1499968.TCA2_3606	5.863e-81	282.0	COG0438@1|root,COG0438@2|Bacteria,1VDFZ@1239|Firmicutes,4HCGX@91061|Bacilli,26U6B@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_23695_5	1380355.JNIJ01000016_gene5779	3.317e-05	47.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3JS0Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158397_k127_2369867_3	378806.STAUR_6997	9.105e-33	138.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42NN9@68525|delta/epsilon subdivisions,2WM5V@28221|Deltaproteobacteria,2Z32B@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase Ligase (LigD)	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158397_k127_2369867_2	937777.Deipe_1300	6.768e-41	158.0	COG4639@1|root,COG4639@2|Bacteria	2|Bacteria	Q	AAA domain	Pnkp	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158397_k127_2369867_4	1288826.MSNKSG1_06143	2.082e-29	129.0	2DM91@1|root,327BS@2|Bacteria,1R3C3@1224|Proteobacteria,1S6CW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2369867_5	502025.Hoch_6029	8.93e-11	72.0	COG0810@1|root,COG0810@2|Bacteria,1PBUV@1224|Proteobacteria,4384F@68525|delta/epsilon subdivisions,2X9X5@28221|Deltaproteobacteria,2YVPR@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	-
SRR25158397_k127_2369867_1	861299.J421_3672	1.619e-107	365.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2369867_0	204669.Acid345_4314	1.138e-123	415.0	COG4941@1|root,COG4941@2|Bacteria,3Y42G@57723|Acidobacteria,2JM1K@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158397_k127_2377156_2	240015.ACP_2543	5.255e-18	93.0	COG1959@1|root,COG1959@2|Bacteria,3Y4X0@57723|Acidobacteria,2JJEV@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158397_k127_2377156_0	378806.STAUR_1769	2.066e-262	814.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2WM3R@28221|Deltaproteobacteria,2YX6W@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158397_k127_2377156_1	880073.Calab_3191	9.039e-116	385.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
SRR25158397_k127_2381288_4	1460634.JCM19037_3889	2.624e-07	57.0	COG2207@1|root,COG2207@2|Bacteria,1V3UI@1239|Firmicutes,4HIEF@91061|Bacilli	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
SRR25158397_k127_2381288_5	1470591.BW41_02453	7.38e-07	61.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria,2K441@204457|Sphingomonadales	204457|Sphingomonadales	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158397_k127_2381288_0	82654.Pse7367_0738	6.302e-47	176.0	COG0705@1|root,COG0705@2|Bacteria,1G5DT@1117|Cyanobacteria,1H961@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158397_k127_2381288_3	204669.Acid345_1499	2.894e-12	76.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K01420,ko:K21556,ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
SRR25158397_k127_2381288_2	504472.Slin_5626	4.39e-25	115.0	2DBJ5@1|root,2Z9IG@2|Bacteria,4NI72@976|Bacteroidetes,47RT8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2406198_2	1449346.JQMO01000002_gene50	1.311e-10	63.0	2C5J1@1|root,3067M@2|Bacteria,2IKFX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2406198_0	1461693.ATO10_05931	1.177e-51	195.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TTZG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_3,HTH_31
SRR25158397_k127_2406198_1	1047013.AQSP01000109_gene2426	3.421e-42	175.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	yukA	-	-	ko:K03466,ko:K12217	-	-	-	-	ko00000,ko02044,ko03036	3.A.12,3.A.7.10.1,3.A.7.9.1	-	-	DUF87,FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N,TraG-D_C,TrwB_AAD_bind
SRR25158397_k127_243314_1	1121861.KB899930_gene199	2.588e-134	440.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,2JPRD@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158397_k127_243314_2	632518.Calow_1631	1.333e-116	388.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,42F1U@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158397_k127_243314_3	523791.Kkor_0087	1.699e-40	166.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1SYRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_243314_5	643648.Slip_1298	5.145e-16	88.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,42KSU@68298|Syntrophomonadaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158397_k127_243314_0	502025.Hoch_1577	5.777e-149	502.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_243314_4	1122611.KB903939_gene313	8.29e-20	96.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2H5BJ@201174|Actinobacteria	201174|Actinobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158397_k127_2441770_1	1120983.KB894575_gene642	8.879e-05	48.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,1JQGH@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_2441770_0	1173028.ANKO01000017_gene224	0.0	1527.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1H7QT@1150|Oscillatoriales	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158397_k127_2444417_9	234267.Acid_6304	6.212e-48	179.0	COG0558@1|root,COG0558@2|Bacteria,3Y520@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158397_k127_2444417_4	234267.Acid_0066	1.699e-66	237.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158397_k127_2444417_15	1297617.JPJD01000023_gene1570	5.036e-33	140.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,268GU@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158397_k127_2444417_2	338966.Ppro_2189	9.232e-110	368.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,43TQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM aminotransferase, class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_2444417_12	234267.Acid_1212	9.343e-34	147.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03770,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158397_k127_2444417_3	1047013.AQSP01000099_gene1495	6.159e-68	240.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158397_k127_2444417_19	1047013.AQSP01000099_gene1496	3.75e-13	74.0	COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.64,2.C.1.2	-	-	MttA_Hcf106
SRR25158397_k127_2444417_1	204669.Acid345_2676	1.888e-114	389.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158397_k127_2444417_20	1242864.D187_006534	1.234e-10	66.0	28S5K@1|root,2ZEH5@2|Bacteria,1NI42@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
SRR25158397_k127_2444417_5	1191523.MROS_0414	2.778e-64	226.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158397_k127_2444417_10	1125863.JAFN01000001_gene284	5.373e-44	174.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158397_k127_2444417_14	761193.Runsl_0610	3.201e-33	133.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,47QCD@768503|Cytophagia	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
SRR25158397_k127_2444417_17	1196323.ALKF01000119_gene5020	5.108e-26	111.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,26USM@186822|Paenibacillaceae	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158397_k127_2444417_0	1123368.AUIS01000002_gene1533	9.071e-139	454.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,2NCCG@225057|Acidithiobacillales	225057|Acidithiobacillales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ChlI
SRR25158397_k127_2444417_11	215803.DB30_7984	2.712e-39	149.0	COG2315@1|root,COG2315@2|Bacteria,1Q2G4@1224|Proteobacteria,4382J@68525|delta/epsilon subdivisions,2X3CK@28221|Deltaproteobacteria,2YVFB@29|Myxococcales	28221|Deltaproteobacteria	S	YjbR	difB	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158397_k127_2444417_21	397945.Aave_4277	8.252e-05	55.0	COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,2VP03@28216|Betaproteobacteria,4AHHC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SRR25158397_k127_2444417_16	163908.KB235896_gene2058	1.473e-31	136.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23,Pesticin,SBP_bac_3
SRR25158397_k127_2444417_22	349520.PPE_04391	0.0001861	55.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,4IPKB@91061|Bacilli	91061|Bacilli	M	conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158397_k127_2444417_18	113355.CM001775_gene547	4.837e-20	106.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G3DW@1117|Cyanobacteria	1117|Cyanobacteria	Q	Polymorphic membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
SRR25158397_k127_2444417_7	395493.BegalDRAFT_2219	1.119e-58	232.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4886@1|root,COG4932@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2444417_8	945713.IALB_2758	6.862e-53	194.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_2444417_6	1121957.ATVL01000008_gene4646	1.041e-58	215.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158397_k127_2451809_3	378806.STAUR_4594	4.883e-39	152.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_2451809_7	215803.DB30_8659	1.171e-06	54.0	COG5662@1|root,COG5662@2|Bacteria,1PC36@1224|Proteobacteria,4387X@68525|delta/epsilon subdivisions,2X3HP@28221|Deltaproteobacteria,2YW5D@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158397_k127_2451809_5	242159.ABO93972	1.46e-30	128.0	COG0127@1|root,KOG3222@2759|Eukaryota,37PRW@33090|Viridiplantae,34JW4@3041|Chlorophyta	3041|Chlorophyta	F	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions	-	-	-	ko:K01519	ko00230,ko00983,ko01100,map00230,map00983,map01100	-	R00426,R00720,R01855,R02100,R02720,R03531,R08243	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158397_k127_2451809_1	1288494.EBAPG3_12100	9.399e-183	603.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2VJBD@28216|Betaproteobacteria,372I3@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DUF1080,FAD_binding_2,GMC_oxred_C
SRR25158397_k127_2451809_0	251221.35214160	1.413e-205	658.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158397_k127_2451809_6	935261.JAGL01000003_gene3150	5.457e-26	113.0	2E4GK@1|root,32ZBS@2|Bacteria,1N72D@1224|Proteobacteria,2UGDA@28211|Alphaproteobacteria,43KNQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
SRR25158397_k127_2451809_2	926554.KI912671_gene402	4.257e-142	460.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR25158397_k127_2451809_4	1123256.KB907957_gene27	8.243e-35	144.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1X38S@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18298	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158397_k127_2452088_0	1184267.A11Q_1394	1.173e-65	233.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2MTS8@213481|Bdellovibrionales,2WTI2@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Domain of unknown function (DUF1974)	-	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
SRR25158397_k127_2452088_1	717606.PaecuDRAFT_2347	2.391e-12	71.0	COG1225@1|root,COG1225@2|Bacteria,1V24A@1239|Firmicutes,4HFUX@91061|Bacilli,26R0T@186822|Paenibacillaceae	91061|Bacilli	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158397_k127_2454001_1	857293.CAAU_1486	3.238e-79	273.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,36DIR@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRR25158397_k127_2454001_2	886293.Sinac_3650	2.213e-60	229.0	COG2318@1|root,COG2318@2|Bacteria,2IZ34@203682|Planctomycetes	203682|Planctomycetes	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158397_k127_2454001_0	1382359.JIAL01000001_gene383	5.527e-145	467.0	COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158397_k127_2454001_4	40571.JOEA01000014_gene1608	6.097e-05	55.0	COG3408@1|root,COG3408@2|Bacteria,2H2QX@201174|Actinobacteria,4E1W5@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C
SRR25158397_k127_2454001_3	318167.Sfri_1759	3.356e-29	120.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,2Q9N9@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158397_k127_246792_16	378806.STAUR_0249	6.58e-13	81.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,42RIU@68525|delta/epsilon subdivisions,2WNC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
SRR25158397_k127_246792_2	1242864.D187_007970	9.721e-92	311.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,438QG@68525|delta/epsilon subdivisions,2X3XV@28221|Deltaproteobacteria,2YXI6@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
SRR25158397_k127_246792_18	316274.Haur_1966	3.299e-10	72.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi,3771I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158397_k127_246792_17	665577.JH993790_gene2775	9.815e-13	80.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158397_k127_246792_6	443143.GM18_0461	1.228e-50	205.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,42ZR0@68525|delta/epsilon subdivisions,2WT3B@28221|Deltaproteobacteria,43UQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_246792_1	443143.GM18_0462	1.579e-93	337.0	COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158397_k127_246792_12	290512.Paes_0751	2.538e-32	132.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158397_k127_246792_15	436229.JOEH01000021_gene7705	6.696e-14	77.0	COG0745@1|root,COG0745@2|Bacteria,2HG0D@201174|Actinobacteria,2NM2Q@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_246792_7	936572.HMPREF1148_1801	1.35e-47	185.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4H4SU@909932|Negativicutes	909932|Negativicutes	G	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158397_k127_246792_3	1458357.BG58_06375	1.076e-65	233.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2W1Y0@28216|Betaproteobacteria,1KFM5@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158397_k127_246792_8	1210884.HG799464_gene11269	1.919e-39	148.0	COG0681@1|root,COG0681@2|Bacteria,2J14X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_246792_0	1460640.JCM19046_2096	2.127e-105	357.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,1ZDE5@1386|Bacillus	91061|Bacilli	Q	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU39370	Amidohydro_1,Amidohydro_3
SRR25158397_k127_246792_14	697281.Mahau_1346	4.643e-17	92.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,42GDD@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158397_k127_246792_20	194867.ALBQ01000044_gene1520	0.0004192	48.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,2K6UW@204457|Sphingomonadales	204457|Sphingomonadales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158397_k127_246792_5	439235.Dalk_0394	1.83e-52	195.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158397_k127_246792_10	204669.Acid345_0088	4.397e-36	149.0	COG0328@1|root,COG0328@2|Bacteria,3Y4EY@57723|Acidobacteria,2JJ1U@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158397_k127_246792_19	309799.DICTH_1145	2.196e-09	67.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	ptsN	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158397_k127_246792_9	1121920.AUAU01000014_gene2832	1.483e-37	156.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LysM
SRR25158397_k127_246792_11	1408424.JHYI01000016_gene2560	8.441e-36	150.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158397_k127_246792_4	1123371.ATXH01000018_gene1391	4.354e-53	193.0	COG2078@1|root,COG2078@2|Bacteria,2GH4V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
SRR25158397_k127_246792_13	290400.Jann_1483	5.342e-19	88.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2UCCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lipid A Biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
SRR25158397_k127_2474834_2	1379270.AUXF01000002_gene1135	8.97e-44	165.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_2474834_1	1121920.AUAU01000028_gene1372	3.632e-75	285.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_2474834_0	518766.Rmar_1861	1.466e-83	289.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1FIPJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158397_k127_2478761_2	272134.KB731324_gene6611	2.628e-81	305.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158397_k127_2478761_0	391625.PPSIR1_28588	5.044e-104	366.0	COG1226@1|root,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158397_k127_2478761_3	1340493.JNIF01000004_gene409	1.901e-49	201.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158397_k127_2478761_5	211114.JOEF01000004_gene6433	2.471e-14	84.0	COG4095@1|root,COG4095@2|Bacteria,2HSC7@201174|Actinobacteria,4ED8C@85010|Pseudonocardiales	201174|Actinobacteria	S	PQ loop repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2478761_1	1379270.AUXF01000001_gene2557	4.502e-96	327.0	COG1878@1|root,COG1878@2|Bacteria,1ZV5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158397_k127_2480590_7	1144275.COCOR_01455	1.776e-33	137.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria	1224|Proteobacteria	S	Doxx family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158397_k127_2480590_4	1459636.NTE_00447	3.461e-93	320.0	COG3832@1|root,arCOG05261@2157|Archaea	2157|Archaea	H	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158397_k127_2480590_5	401053.AciPR4_0338	3.745e-43	160.0	COG0640@1|root,COG0640@2|Bacteria,3Y4SS@57723|Acidobacteria,2JN6X@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158397_k127_2480590_0	1379270.AUXF01000001_gene1951	7.907e-144	471.0	COG0577@1|root,COG0577@2|Bacteria,1ZSUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_2480590_3	379066.GAU_0844	1.394e-99	346.0	COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_2480590_2	1379270.AUXF01000001_gene1949	1.616e-102	346.0	COG0845@1|root,COG0845@2|Bacteria,1ZU07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158397_k127_2480590_6	1121272.KB903249_gene1234	1.011e-41	172.0	COG0457@1|root,COG0457@2|Bacteria,2IMH6@201174|Actinobacteria,4DI3R@85008|Micromonosporales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158397_k127_2480590_8	479435.Kfla_3373	6.703e-20	104.0	28XC1@1|root,2ZJ9X@2|Bacteria,2H1HK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2480590_1	661478.OP10G_4395	3.061e-132	442.0	COG0465@1|root,COG0465@2|Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798,ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403,M00742	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03019,ko03110,ko04131,ko04147	3.A.16.1	-	-	AAA,Peptidase_M41,TPR_19,TPR_20
SRR25158397_k127_2480590_9	479435.Kfla_3374	5.266e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,2IMH6@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158397_k127_2481554_3	981085.XP_010100525.1	2.317e-09	66.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MGX@33090|Viridiplantae,3GE77@35493|Streptophyta,4JFY3@91835|fabids	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241	-	ko:K07761,ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
SRR25158397_k127_2481554_2	1255043.TVNIR_1018	1.101e-25	111.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.14.99.48,1.14.99.57	ko:K07145,ko:K21481	ko00860,ko01110,map00860,map01110	-	R10468,R10510	RC03185	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158397_k127_2481554_0	926549.KI421517_gene3913	1.287e-77	276.0	COG5012@1|root,COG5012@2|Bacteria,4NRCW@976|Bacteroidetes,47UR1@768503|Cytophagia	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158397_k127_2481554_1	555779.Dthio_PD1133	3.275e-52	200.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Y5I@68525|delta/epsilon subdivisions,2WUGI@28221|Deltaproteobacteria,2MEJ5@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158397_k127_2483643_0	552811.Dehly_1611	1.151e-56	200.0	COG3943@1|root,COG3943@2|Bacteria,2G9QK@200795|Chloroflexi	200795|Chloroflexi	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
SRR25158397_k127_2483643_3	1173027.Mic7113_4818	3.509e-18	87.0	COG0610@1|root,COG0610@2|Bacteria,1G1HD@1117|Cyanobacteria,1H9GR@1150|Oscillatoriales	1117|Cyanobacteria	L	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII
SRR25158397_k127_2483643_2	1121033.AUCF01000004_gene4653	2.915e-23	112.0	COG0535@1|root,COG0535@2|Bacteria,1PHFS@1224|Proteobacteria,2VE4X@28211|Alphaproteobacteria,2JVSI@204441|Rhodospirillales	204441|Rhodospirillales	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158397_k127_2483643_1	298654.FraEuI1c_0853	2.12e-32	131.0	COG2346@1|root,COG2346@2|Bacteria,2IJM0@201174|Actinobacteria	201174|Actinobacteria	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	-
SRR25158397_k127_2483643_6	1249627.D779_1779	0.0001042	53.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales	135613|Chromatiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158397_k127_2483939_0	251221.35213714	2.315e-241	782.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
SRR25158397_k127_2483939_4	251221.35210597	7.33e-05	53.0	2DV7W@1|root,33UJH@2|Bacteria,1GDKX@1117|Cyanobacteria	1117|Cyanobacteria	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Dockerin_1
SRR25158397_k127_2483939_1	1121904.ARBP01000013_gene445	7.099e-152	492.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_2483939_2	497964.CfE428DRAFT_4783	5.009e-77	269.0	COG3214@1|root,COG3214@2|Bacteria,46UTW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158397_k127_2488555_13	1205680.CAKO01000006_gene3352	4.546e-41	174.0	COG0438@1|root,COG0438@2|Bacteria,1MWTJ@1224|Proteobacteria,2TS6N@28211|Alphaproteobacteria,2JY9Q@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase Family 4	-	-	2.4.1.252	ko:K13657	-	-	R09733	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_2488555_8	314345.SPV1_00477	6.163e-57	221.0	2B8B9@1|root,33Q4Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2488555_7	292564.Cyagr_1206	4.873e-59	229.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G0HY@1117|Cyanobacteria,22TGG@167375|Cyanobium	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158397_k127_2488555_4	1198114.AciX9_1342	6.177e-64	237.0	COG0438@1|root,COG0438@2|Bacteria,3Y34S@57723|Acidobacteria,2JIQT@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158397_k127_2488555_3	314345.SPV1_07451	1.677e-92	316.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn,Glycos_transf_1
SRR25158397_k127_2488555_10	489825.LYNGBM3L_52710	2.856e-51	190.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
SRR25158397_k127_2488555_6	357808.RoseRS_2408	1.046e-59	232.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158397_k127_2488555_1	313606.M23134_08047	4.458e-130	426.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158397_k127_2488555_9	550540.Fbal_0461	2.492e-52	206.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD,Peptidase_S8
SRR25158397_k127_2488555_2	290397.Adeh_3188	3.928e-93	329.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,FTP,Laminin_G_3,PA,Peptidase_M36
SRR25158397_k127_2488555_5	378806.STAUR_0559	4.721e-63	237.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8
SRR25158397_k127_2488555_11	1122604.JONR01000009_gene2319	3.655e-50	182.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,1S3T2@1236|Gammaproteobacteria,1X7BR@135614|Xanthomonadales	135614|Xanthomonadales	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
SRR25158397_k127_2488555_12	1128421.JAGA01000002_gene586	2.057e-43	176.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158397_k127_2488555_14	296591.Bpro_1835	2.039e-07	63.0	COG0596@1|root,COG0596@2|Bacteria,1QU8M@1224|Proteobacteria,2WGJ0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158397_k127_2488555_0	1242864.D187_008863	0.0	1207.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158397_k127_2490524_8	1439940.BAY1663_04940	2.947e-17	84.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_2490524_1	1158338.JNLJ01000001_gene789	1.179e-139	458.0	COG0191@1|root,COG0191@2|Bacteria,2G3VP@200783|Aquificae	200783|Aquificae	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158397_k127_2490524_9	1278073.MYSTI_00561	3.99e-15	85.0	2E2RY@1|root,32XUA@2|Bacteria,1N9C1@1224|Proteobacteria,42XP0@68525|delta/epsilon subdivisions,2WT7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR25158397_k127_2490524_5	861299.J421_0742	4.696e-93	314.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158397_k127_2490524_3	1292034.OR37_00751	7.708e-129	428.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TQRF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.13.22,3.4.16.4	ko:K01286,ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Beta-lactamase
SRR25158397_k127_2490524_6	861299.J421_2715	1.081e-62	226.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158397_k127_2490524_4	448385.sce3597	3.394e-115	387.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_2490524_7	903818.KI912268_gene2297	2.275e-23	117.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria	57723|Acidobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
SRR25158397_k127_2490524_11	1320556.AVBP01000021_gene313	0.0001656	53.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,43HW5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158397_k127_2490524_0	2850.Phatr49505	7.503e-190	602.0	COG3033@1|root,2QU0C@2759|Eukaryota	2759|Eukaryota	E	lyase activity	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase,Trp_DMAT
SRR25158397_k127_2490524_10	243231.GSU3120	2.441e-05	53.0	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,42XU4@68525|delta/epsilon subdivisions,2WSMH@28221|Deltaproteobacteria,43VU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
SRR25158397_k127_2490524_2	756272.Plabr_0480	1.642e-131	427.0	COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158397_k127_2500971_12	497964.CfE428DRAFT_6546	4.478e-25	119.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158397_k127_2500971_0	316067.Geob_0790	0.0	1094.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158397_k127_2500971_6	234267.Acid_3826	2.351e-61	234.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158397_k127_2500971_7	234267.Acid_5445	3.912e-61	235.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158397_k127_2500971_4	234267.Acid_3826	4.569e-84	299.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158397_k127_2500971_5	234267.Acid_5444	1.844e-80	292.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158397_k127_2500971_13	1079986.JH164838_gene4242	3.843e-19	94.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158397_k127_2500971_2	595536.ADVE02000001_gene850	1.349e-193	621.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,36Y0V@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158397_k127_2500971_10	63737.Npun_R2701	1.611e-27	113.0	COG2442@1|root,COG2442@2|Bacteria,1G8FX@1117|Cyanobacteria,1HPIE@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2500971_1	1123276.KB893247_gene178	1.548e-265	844.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
SRR25158397_k127_2500971_14	290398.Csal_2639	2.668e-05	51.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1XM4X@135619|Oceanospirillales	135619|Oceanospirillales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158397_k127_2500971_3	663278.Ethha_2687	9.49e-178	569.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158397_k127_2500971_11	161528.ED21_20899	3.042e-26	126.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,2K697@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158397_k127_2500971_8	240015.ACP_2617	7.54e-52	186.0	COG0105@1|root,COG0105@2|Bacteria,3Y4MW@57723|Acidobacteria,2JJD4@204432|Acidobacteriia	204432|Acidobacteriia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158397_k127_2500971_9	1265502.KB905953_gene759	1.414e-32	132.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGKF@28216|Betaproteobacteria,4AGRT@80864|Comamonadaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
SRR25158397_k127_2506124_0	313596.RB2501_16209	1.882e-144	472.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,1HZDE@117743|Flavobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_2506124_4	1121920.AUAU01000013_gene1762	4.226e-22	100.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158397_k127_2506124_3	204669.Acid345_0069	1.372e-42	172.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158397_k127_2506124_1	1121346.KB899815_gene1901	1.152e-121	420.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158397_k127_2506124_2	1173022.Cri9333_3748	9.263e-75	261.0	COG0358@1|root,COG0358@2|Bacteria,1G0TV@1117|Cyanobacteria,1H7ZY@1150|Oscillatoriales	1117|Cyanobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
SRR25158397_k127_2519808_15	749222.Nitsa_0869	2.279e-09	68.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,42RP4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158397_k127_2519808_3	1499967.BAYZ01000009_gene5286	1.646e-87	313.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR25158397_k127_2519808_11	765912.Thimo_2267	1.971e-21	97.0	COG0636@1|root,COG0636@2|Bacteria,1N5D3@1224|Proteobacteria,1SBV1@1236|Gammaproteobacteria,1WZ48@135613|Chromatiales	135613|Chromatiales	U	Belongs to the V-ATPase proteolipid subunit family	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158397_k127_2519808_1	1094980.Mpsy_2506	1.088e-169	559.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,2N93M@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SRR25158397_k127_2519808_2	903818.KI912268_gene1990	3.79e-156	505.0	COG1156@1|root,COG1156@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158397_k127_2519808_12	1384065.JAGS01000001_gene2666	9.505e-18	98.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3WH3C@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SRR25158397_k127_2519808_14	290397.Adeh_1321	1.291e-11	79.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158397_k127_2519808_0	671143.DAMO_1933	0.0	1286.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158397_k127_2519808_8	452637.Oter_1455	3.498e-30	135.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158397_k127_2519808_7	1382359.JIAL01000001_gene1290	5.996e-33	147.0	COG1538@1|root,COG1538@2|Bacteria,3Y5F3@57723|Acidobacteria,2JK84@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158397_k127_2519808_10	1303518.CCALI_01175	9.435e-23	99.0	COG0607@1|root,32YCZ@2|Bacteria	2|Bacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR25158397_k127_2519808_9	1382306.JNIM01000001_gene3599	3.221e-27	116.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158397_k127_2519808_5	1242864.D187_009944	3.091e-47	189.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158397_k127_2519808_4	309807.SRU_1984	1.596e-63	229.0	2CHNQ@1|root,2Z7KM@2|Bacteria,4NHAA@976|Bacteroidetes,1FK2S@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2519808_13	1100720.ALKN01000037_gene1886	6.282e-14	75.0	2EIMJ@1|root,33CCU@2|Bacteria,1NMXZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2519808_6	525904.Tter_2724	1.123e-40	155.0	COG3439@1|root,COG3439@2|Bacteria,2NPV1@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158397_k127_2526185_3	1121920.AUAU01000013_gene1734	5.346e-41	155.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	MTS
SRR25158397_k127_2526185_4	1237500.ANBA01000008_gene95	2.331e-36	146.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158397_k127_2526185_1	745310.G432_16040	4.573e-83	299.0	COG4529@1|root,COG4529@2|Bacteria,1MU3U@1224|Proteobacteria,2TUBM@28211|Alphaproteobacteria,2K079@204457|Sphingomonadales	204457|Sphingomonadales	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRR25158397_k127_2526185_2	158189.SpiBuddy_0974	6.391e-42	160.0	COG5646@1|root,COG5646@2|Bacteria,2JAS4@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158397_k127_2526185_0	204669.Acid345_0622	6.393e-147	475.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria,2JHR4@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_2526217_0	1267535.KB906767_gene597	1.075e-134	451.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158397_k127_2526217_1	869210.Marky_1030	2.152e-56	211.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,FAD_oxidored,HI0933_like,NAD_binding_8,Trp_halogenase
SRR25158397_k127_2526217_2	1120999.JONM01000005_gene3774	6.472e-50	196.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KPBY@206351|Neisseriales	206351|Neisseriales	I	Squalene synthase HpnD	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158397_k127_2526217_3	671143.DAMO_1478	2.798e-05	48.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158397_k127_2534888_6	1429851.X548_17165	0.0001961	51.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2534888_1	1192034.CAP_3083	1.851e-151	492.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2YTX0@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_2534888_0	290397.Adeh_2937	8.343e-191	620.0	COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria,43E6J@68525|delta/epsilon subdivisions,2X7H9@28221|Deltaproteobacteria,2Z3GG@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M36
SRR25158397_k127_2534888_2	118173.KB235914_gene3902	1.702e-77	273.0	COG1215@1|root,COG1215@2|Bacteria,1G5YB@1117|Cyanobacteria,1HB60@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_2534888_4	331678.Cphamn1_0242	8.123e-38	151.0	COG0400@1|root,COG0400@2|Bacteria,1FF1R@1090|Chlorobi	1090|Chlorobi	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
SRR25158397_k127_2534888_5	1242864.D187_007053	3.407e-05	56.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_2535777_2	1242864.D187_008863	4.916e-28	132.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158397_k127_2535777_0	234267.Acid_2705	8.326e-165	565.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158397_k127_2535777_1	1089548.KI783301_gene2277	4.523e-42	162.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,3WFTM@539002|Bacillales incertae sedis	91061|Bacilli	K	YsiA-like protein, C-terminal region	fadR	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158397_k127_2548222_3	1384054.N790_01640	2.901e-52	198.0	COG1595@1|root,COG1595@2|Bacteria,1RCMS@1224|Proteobacteria,1S55Z@1236|Gammaproteobacteria,1X59U@135614|Xanthomonadales	135614|Xanthomonadales	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_2548222_0	269799.Gmet_3085	1.581e-124	430.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
SRR25158397_k127_2548222_6	1452535.JARD01000006_gene2948	1.062e-17	97.0	COG3757@1|root,COG4932@1|root,COG3757@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	DUF1906,Glyco_hydro_92,Neocarzinostat
SRR25158397_k127_2548222_5	111781.Lepto7376_1932	1.782e-20	108.0	COG0457@1|root,COG3210@1|root,COG4995@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,TPR_12,TPR_7
SRR25158397_k127_2548222_8	1499967.BAYZ01000135_gene87	1.694e-06	61.0	COG4249@1|root,COG4249@2|Bacteria,2NQXX@2323|unclassified Bacteria	2|Bacteria	S	Caspase domain	atmc2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158397_k127_2548222_4	861299.J421_1529	1.473e-35	150.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158397_k127_2548222_7	1028800.RG540_CH27040	4.086e-08	66.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2TQQR@28211|Alphaproteobacteria,4BAW7@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158397_k127_2548222_2	1379698.RBG1_1C00001G0607	2.608e-86	307.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158397_k127_2548222_1	215803.DB30_1115	4.507e-119	419.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,42QJM@68525|delta/epsilon subdivisions,2WXDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
SRR25158397_k127_2561792_5	290397.Adeh_4352	4.107e-33	133.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158397_k127_2561792_2	767817.Desgi_2717	2.116e-201	641.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,26007@186807|Peptococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
SRR25158397_k127_2561792_7	1144275.COCOR_07031	4.68e-09	64.0	COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria,42TGV@68525|delta/epsilon subdivisions,2WQZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2561792_6	1121403.AUCV01000016_gene4416	2.096e-32	132.0	COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria,42TGV@68525|delta/epsilon subdivisions,2WQZJ@28221|Deltaproteobacteria,2MKSF@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2561792_3	1303518.CCALI_01058	1.865e-169	539.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158397_k127_2561792_4	1267533.KB906737_gene1681	8.029e-37	146.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158397_k127_2561792_0	649638.Trad_2519	0.0	1500.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1WIRD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158397_k127_2561792_8	754027.HMPREF9554_00026	8.759e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158397_k127_2561792_1	448385.sce2453	4.991e-312	968.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SRR25158397_k127_2564783_1	1047013.AQSP01000139_gene2383	8.283e-20	103.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516,ko:K05801	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DUF4388,DnaJ,DnaJ_C,TerB,WD40
SRR25158397_k127_2564783_0	1499967.BAYZ01000195_gene3095	4.304e-47	191.0	COG0457@1|root,COG0457@2|Bacteria,2NPEN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
SRR25158397_k127_2566889_6	1232410.KI421416_gene2621	9.526e-28	118.0	2EF9T@1|root,3392P@2|Bacteria,1P8J3@1224|Proteobacteria,4324V@68525|delta/epsilon subdivisions,2WYC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2566889_1	1278073.MYSTI_00224	2.498e-115	382.0	COG1075@1|root,COG1075@2|Bacteria,1MXXB@1224|Proteobacteria,438M0@68525|delta/epsilon subdivisions,2X3VC@28221|Deltaproteobacteria,2YX83@29|Myxococcales	28221|Deltaproteobacteria	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRR25158397_k127_2566889_0	1192034.CAP_3457	5.621e-146	472.0	COG2308@1|root,COG2308@2|Bacteria,1Q3RI@1224|Proteobacteria,439JB@68525|delta/epsilon subdivisions,2X4VX@28221|Deltaproteobacteria,2YZQ5@29|Myxococcales	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2566889_2	1121920.AUAU01000008_gene1552	1.03e-95	316.0	COG1100@1|root,COG1100@2|Bacteria,3Y7CQ@57723|Acidobacteria	57723|Acidobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
SRR25158397_k127_2566889_4	903818.KI912268_gene3366	2.354e-64	224.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SRR25158397_k127_2566889_3	234267.Acid_3167	1.511e-69	241.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria	57723|Acidobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158397_k127_2566889_7	1157490.EL26_20570	1.389e-24	106.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,278JJ@186823|Alicyclobacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158397_k127_2566889_5	269799.Gmet_3422	2.686e-62	231.0	COG2812@1|root,COG3266@1|root,COG2812@2|Bacteria,COG3266@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,43T4B@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158397_k127_2595732_0	509635.N824_10045	1.194e-196	631.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158397_k127_2595732_3	234267.Acid_5931	1.444e-71	250.0	COG0730@1|root,COG0730@2|Bacteria,3Y4IM@57723|Acidobacteria	57723|Acidobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158397_k127_2595732_1	234267.Acid_7636	2.506e-165	554.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158397_k127_2595732_2	483219.LILAB_20530	4.317e-146	476.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_2609790_3	314285.KT71_10914	1.401e-22	113.0	COG1629@1|root,COG4771@2|Bacteria,1RAXV@1224|Proteobacteria,1S3M5@1236|Gammaproteobacteria,1J7SZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_2609790_2	335543.Sfum_2204	3.361e-36	157.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Stage II sporulation	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
SRR25158397_k127_2609790_0	448385.sce3935	2.095e-75	266.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRR25158397_k127_2609790_1	861299.J421_0944	2.269e-67	235.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158397_k127_2615413_1	395492.Rleg2_1811	1.574e-115	375.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2TU9J@28211|Alphaproteobacteria,4B9F0@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158397_k127_2615413_5	870187.Thini_2161	9.357e-48	195.0	2CC4B@1|root,3267W@2|Bacteria,1RJP5@1224|Proteobacteria,1SQ9U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2615413_0	1121373.KB903627_gene2912	7.971e-136	463.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRR25158397_k127_2615413_4	378806.STAUR_6609	1.887e-48	192.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQA3@28221|Deltaproteobacteria,2YVD7@29|Myxococcales	28221|Deltaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287,ko:K18589	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	DHFR_1
SRR25158397_k127_2615413_2	1242864.D187_005109	3.684e-72	272.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2X2AQ@28221|Deltaproteobacteria,2Z25Q@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158397_k127_2615413_3	1047013.AQSP01000123_gene1531	2.931e-71	269.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158397_k127_2619778_1	497964.CfE428DRAFT_1237	2.89e-128	417.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158397_k127_2619778_0	497964.CfE428DRAFT_1238	7.932e-188	613.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158397_k127_2619778_2	497964.CfE428DRAFT_1239	1.675e-16	90.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_262624_4	1089550.ATTH01000001_gene1755	1.137e-16	89.0	2DQJQ@1|root,337AP@2|Bacteria,4PEU5@976|Bacteroidetes,1FJMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRR25158397_k127_262624_2	1166018.FAES_1111	8.933e-27	115.0	2DR2Z@1|root,339YC@2|Bacteria,4P4XI@976|Bacteroidetes,47VKU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
SRR25158397_k127_262624_0	448385.sce0244	5.548e-197	633.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales	28221|Deltaproteobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
SRR25158397_k127_262624_3	1156935.QWE_16848	6.881e-22	113.0	2E8GZ@1|root,332V8@2|Bacteria,1NDF5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_262624_5	483219.LILAB_12830	0.0004012	53.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1Q2N3@1224|Proteobacteria,4388W@68525|delta/epsilon subdivisions,2XA2N@28221|Deltaproteobacteria,2YXAB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
SRR25158397_k127_262624_1	246197.MXAN_4511	7.019e-63	218.0	COG1985@1|root,COG1985@2|Bacteria,1PXWC@1224|Proteobacteria	1224|Proteobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158397_k127_2626958_4	1125863.JAFN01000001_gene2409	1.153e-83	286.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158397_k127_2626958_0	485918.Cpin_7008	9.453e-199	638.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158397_k127_2626958_9	1174528.JH992898_gene966	1.477e-15	83.0	2DM1K@1|root,31BCJ@2|Bacteria,1G6WG@1117|Cyanobacteria,1JIVN@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2626958_6	398767.Glov_3128	1.006e-30	132.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158397_k127_2626958_7	1379698.RBG1_1C00001G1058	4.443e-22	104.0	COG0839@1|root,COG0839@2|Bacteria,2NPUC@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158397_k127_2626958_3	1191523.MROS_2033	2.502e-91	312.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158397_k127_2626958_1	671143.DAMO_1616	3.935e-108	370.0	COG1034@1|root,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRR25158397_k127_2626958_8	639283.Snov_2789	5.355e-19	99.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,3EZ6E@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	PPIC-type PPIASE domain	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
SRR25158397_k127_2626958_5	903818.KI912268_gene1512	1.581e-31	138.0	COG0745@1|root,COG0745@2|Bacteria,3Y81M@57723|Acidobacteria	903818.KI912268_gene1512|-	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2626958_2	1379698.RBG1_1C00001G0675	4.364e-101	346.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158397_k127_2626958_10	1313172.YM304_21190	6.677e-07	52.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K07004,ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,HYR,fn3
SRR25158397_k127_2628371_14	335543.Sfum_0757	5.632e-19	100.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MQMV@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SRR25158397_k127_2628371_9	1047013.AQSP01000110_gene63	2.412e-30	130.0	COG4105@1|root,COG4105@2|Bacteria,2NQ7U@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	bamD	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
SRR25158397_k127_2628371_4	1430331.EP10_16745	1.74e-77	266.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1WE4J@129337|Geobacillus	91061|Bacilli	G	Ribulose-phosphate 3 epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158397_k127_2628371_17	1121440.AUMA01000003_gene2934	6.253e-11	67.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2MDBG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_2628371_18	391037.Sare_3480	8.935e-07	59.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4D8KT@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_2628371_0	309799.DICTH_1451	5.231e-232	746.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158397_k127_2628371_8	1304888.ATWF01000001_gene2405	1.698e-36	151.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2GFA3@200930|Deferribacteres	200930|Deferribacteres	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_2628371_13	1487953.JMKF01000081_gene4233	1.439e-19	93.0	COG4118@1|root,COG4118@2|Bacteria,1G8FZ@1117|Cyanobacteria,1HDKF@1150|Oscillatoriales	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158397_k127_2628371_7	306281.AJLK01000072_gene670	1.583e-40	153.0	COG3744@1|root,COG3744@2|Bacteria,1G647@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_2628371_19	1254432.SCE1572_39790	2.064e-06	51.0	COG0446@1|root,COG0446@2|Bacteria,1RET8@1224|Proteobacteria	1224|Proteobacteria	S	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2628371_16	1000565.METUNv1_03355	6.253e-11	67.0	COG3668@1|root,COG3668@2|Bacteria,1PUJD@1224|Proteobacteria,2WAUE@28216|Betaproteobacteria,2KZHN@206389|Rhodocyclales	206389|Rhodocyclales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158397_k127_2628371_5	1210884.HG799477_gene15448	4.336e-77	262.0	COG3663@1|root,COG3663@2|Bacteria,2J38J@203682|Planctomycetes	203682|Planctomycetes	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158397_k127_2628371_1	316067.Geob_2159	2.099e-171	562.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158397_k127_2628371_3	1121918.ARWE01000001_gene1268	1.181e-82	286.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR25158397_k127_2628371_11	289376.THEYE_A1563	2.736e-22	107.0	COG0835@1|root,COG0835@2|Bacteria,3J0PG@40117|Nitrospirae	40117|Nitrospirae	NT	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158397_k127_2628371_10	316067.Geob_2164	9.467e-26	117.0	COG0745@1|root,COG0745@2|Bacteria,1NV0N@1224|Proteobacteria,42ZH3@68525|delta/epsilon subdivisions,2WUW0@28221|Deltaproteobacteria,43UQG@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,zinc_ribbon_4
SRR25158397_k127_2628371_6	404380.Gbem_0746	2.225e-51	207.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,43UH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
SRR25158397_k127_2628371_2	443143.GM18_3603	8.505e-88	299.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,43UG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR25158397_k127_2628371_12	1238450.VIBNISOn1_1750018	1.255e-19	100.0	COG5361@1|root,COG5361@2|Bacteria,1NBVB@1224|Proteobacteria,1SES6@1236|Gammaproteobacteria,1Y1IS@135623|Vibrionales	135623|Vibrionales	S	Neurotransmitter-gated ion-channel ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Neur_chan_LBD
SRR25158397_k127_263203_3	1129374.AJE_12139	3.585e-134	440.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,465Q7@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_263203_4	1123256.KB907931_gene2864	8.432e-96	330.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1X41T@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	styS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
SRR25158397_k127_263203_11	234267.Acid_6068	3.512e-16	84.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,Pkinase_Tyr
SRR25158397_k127_263203_9	32264.tetur07g02740.1	1.631e-34	148.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa,3CSKJ@33213|Bilateria,41YHD@6656|Arthropoda	33208|Metazoa	M	Pectinacetylesterase	NOTUM	GO:0000902,GO:0000904,GO:0003002,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008045,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030163,GO:0030178,GO:0030182,GO:0031175,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0040011,GO:0042157,GO:0042159,GO:0042221,GO:0042330,GO:0042578,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0052689,GO:0060429,GO:0060828,GO:0061564,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090090,GO:0097485,GO:0098732,GO:0120036,GO:0120039,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
SRR25158397_k127_263203_7	483219.LILAB_08010	1.056e-48	181.0	COG2850@1|root,COG2850@2|Bacteria	2|Bacteria	P	peptidyl-arginine hydroxylation	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158397_k127_263203_6	1118054.CAGW01000089_gene3484	1.656e-83	289.0	COG1277@1|root,COG1277@2|Bacteria,1TRV1@1239|Firmicutes,4HBBV@91061|Bacilli,26SYW@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter permease	bcrB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158397_k127_263203_5	1329516.JPST01000003_gene1081	1.077e-86	296.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,27BKK@186824|Thermoactinomycetaceae	91061|Bacilli	V	ATP binding cassette transporter ABC protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_263203_8	1499680.CCFE01000023_gene2560	2.072e-38	154.0	COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HD6X@91061|Bacilli,1ZCPP@1386|Bacillus	91061|Bacilli	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158397_k127_263203_2	1304872.JAGC01000003_gene2613	4.034e-184	623.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_263203_0	1304872.JAGC01000003_gene2613	2.842e-199	647.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_263203_1	204669.Acid345_0621	1.057e-184	601.0	COG0612@1|root,COG0612@2|Bacteria,3Y322@57723|Acidobacteria,2JP25@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
SRR25158397_k127_263203_10	204669.Acid345_0622	9.976e-28	114.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria,2JHR4@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_2639648_11	700598.Niako_1819	5.992e-33	147.0	COG0711@1|root,COG2319@1|root,COG0711@2|Bacteria,COG2319@2|Bacteria,4NKC3@976|Bacteroidetes,1J18Y@117747|Sphingobacteriia	976|Bacteroidetes	C	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SRR25158397_k127_2639648_8	1242864.D187_009424	1.052e-47	189.0	COG3209@1|root,COG3209@2|Bacteria,1Q3W1@1224|Proteobacteria,439Q0@68525|delta/epsilon subdivisions,2X51Z@28221|Deltaproteobacteria,2Z002@29|Myxococcales	28221|Deltaproteobacteria	M	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG
SRR25158397_k127_2639648_22	1457250.BBMO01000001_gene1172	0.0005471	52.0	COG1520@1|root,COG3979@1|root,arCOG02556@2157|Archaea,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_2,PQQ_3
SRR25158397_k127_2639648_10	1379270.AUXF01000002_gene1393	1.006e-43	167.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SRR25158397_k127_2639648_0	635013.TherJR_0997	9.657e-171	577.0	COG0395@1|root,COG5001@1|root,COG5002@1|root,COG0395@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9
SRR25158397_k127_2639648_17	215803.DB30_8912	4.285e-18	93.0	COG1994@1|root,COG1994@2|Bacteria,1Q2IJ@1224|Proteobacteria,433TS@68525|delta/epsilon subdivisions,2X3F7@28221|Deltaproteobacteria,2YVTY@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158397_k127_2639648_9	926561.KB900617_gene1577	4.841e-44	184.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,248BK@186801|Clostridia	186801|Clostridia	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
SRR25158397_k127_2639648_2	1121015.N789_14020	1.382e-134	443.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X5QJ@135614|Xanthomonadales	135614|Xanthomonadales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158397_k127_2639648_19	1131269.AQVV01000001_gene1393	3.988e-09	61.0	2CBGA@1|root,33A66@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2639648_3	1144275.COCOR_03465	7.673e-126	415.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158397_k127_2639648_15	251221.35211984	4.982e-23	114.0	2EA12@1|root,3346D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158397_k127_2639648_7	1121920.AUAU01000004_gene805	5.001e-56	209.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,3Y578@57723|Acidobacteria	57723|Acidobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158397_k127_2639648_4	867845.KI911784_gene3180	9.607e-101	339.0	COG0492@1|root,COG0492@2|Bacteria,2G87N@200795|Chloroflexi,377CC@32061|Chloroflexia	32061|Chloroflexia	O	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
SRR25158397_k127_2639648_16	318167.Sfri_0286	4.999e-19	92.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,2QBRI@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
SRR25158397_k127_2639648_12	861299.J421_0105	4.691e-28	119.0	28NRS@1|root,2ZBQZ@2|Bacteria,1ZV13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2639648_13	502025.Hoch_3075	3.325e-25	110.0	COG0454@1|root,COG0456@2|Bacteria,1N8UF@1224|Proteobacteria,4338X@68525|delta/epsilon subdivisions,2X7XH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2639648_14	1454007.JAUG01000041_gene558	3.038e-23	104.0	2EA47@1|root,33494@2|Bacteria,4P7ZV@976|Bacteroidetes,1J00A@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2639648_1	314260.PB2503_04017	4.243e-157	513.0	COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria	1224|Proteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CARDB,FTP,PA,Peptidase_M36
SRR25158397_k127_2639648_6	864702.OsccyDRAFT_4243	1.543e-60	225.0	COG4191@1|root,COG4191@2|Bacteria,1G5TB@1117|Cyanobacteria,1HB2V@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2639648_18	1120973.AQXL01000121_gene99	3.913e-11	70.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,2780P@186823|Alicyclobacillaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_2639648_5	365046.Rta_25440	1.863e-80	287.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2WGNE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR25158397_k127_2645906_4	395965.Msil_0219	7.595e-24	110.0	COG0671@1|root,COG0671@2|Bacteria,1PE6X@1224|Proteobacteria,2U712@28211|Alphaproteobacteria,3NCFC@45404|Beijerinckiaceae	28211|Alphaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158397_k127_2645906_0	483219.LILAB_14940	1.563e-104	365.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158397_k127_2645906_2	289376.THEYE_A1784	1.285e-63	225.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	MGDG_synth,PHP
SRR25158397_k127_2645906_3	886293.Sinac_5235	5.113e-50	198.0	COG1215@1|root,COG1215@2|Bacteria,2IZJX@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
SRR25158397_k127_2645906_1	1121019.AUMN01000020_gene1649	1.378e-102	338.0	COG3382@1|root,COG3382@2|Bacteria,2GMX2@201174|Actinobacteria,1WC90@1268|Micrococcaceae	201174|Actinobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
SRR25158397_k127_2653511_2	1267534.KB906755_gene4692	4.13e-49	188.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2653511_1	555088.DealDRAFT_2158	2.09e-51	190.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	yycF	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_2653511_0	867903.ThesuDRAFT_01687	2.36e-111	371.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WCW0@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158397_k127_2653511_6	1123053.AUDG01000001_gene2390	0.0004316	51.0	2E0TQ@1|root,32WBD@2|Bacteria,1N4HN@1224|Proteobacteria,1SC43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2653511_5	690585.JNNU01000002_gene4675	2.029e-07	63.0	COG1748@1|root,COG1748@2|Bacteria,1P35E@1224|Proteobacteria,2TSYM@28211|Alphaproteobacteria,4BBHJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166,Sacchrp_dh_NADP
SRR25158397_k127_2653511_3	1242864.D187_000636	2.822e-47	182.0	2DGKH@1|root,2ZWDA@2|Bacteria,1Q2F1@1224|Proteobacteria,4380V@68525|delta/epsilon subdivisions,2X3AV@28221|Deltaproteobacteria,2YV6E@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2653511_4	760568.Desku_0493	2.867e-26	114.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_2653511_7	665571.STHERM_c22050	0.0005698	51.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
SRR25158397_k127_2665290_7	743721.Psesu_2705	6.669e-67	253.0	COG3861@1|root,COG3861@2|Bacteria,1MWBU@1224|Proteobacteria,1S1WP@1236|Gammaproteobacteria,1XCQG@135614|Xanthomonadales	135614|Xanthomonadales	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
SRR25158397_k127_2665290_4	243231.GSU2744	5.176e-97	331.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,43C55@68525|delta/epsilon subdivisions,2X7FI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_2665290_14	1089546.AQUI01000002_gene2055	2.574e-07	63.0	COG3858@1|root,COG3858@2|Bacteria,2HZ7I@201174|Actinobacteria,409RI@622450|Actinopolysporales	201174|Actinobacteria	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158397_k127_2665290_2	204669.Acid345_1212	8.809e-125	408.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria,2JI6S@204432|Acidobacteriia	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158397_k127_2665290_5	1121920.AUAU01000004_gene629	8.948e-81	290.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158397_k127_2665290_12	887898.HMPREF0551_0311	1.934e-39	159.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria,1K8C3@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Eukaryotic-type carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase,VPEP
SRR25158397_k127_2665290_1	1379698.RBG1_1C00001G0513	1.612e-151	490.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158397_k127_2665290_8	313606.M23134_05227	2.025e-53	214.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
SRR25158397_k127_2665290_6	1128421.JAGA01000002_gene1141	1.109e-69	243.0	COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria	2|Bacteria	I	Enoyl-CoA hydratase/isomerase	atuE	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158397_k127_2665290_0	1128421.JAGA01000002_gene1149	1.009e-151	504.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158397_k127_2665290_13	340177.Cag_1560	8.686e-29	131.0	COG2706@1|root,COG2911@1|root,COG2931@1|root,COG2706@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Big_5,Laminin_G_3,VCBS
SRR25158397_k127_2665290_3	485913.Krac_4425	2.567e-97	328.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158397_k127_2665290_10	402612.FP1223	2.106e-45	176.0	COG0569@1|root,COG0569@2|Bacteria,4PKFI@976|Bacteroidetes	976|Bacteroidetes	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158397_k127_2665290_9	1303518.CCALI_00092	5.06e-47	179.0	COG1079@1|root,COG1079@2|Bacteria	2|Bacteria	S	Belongs to the binding-protein-dependent transport system permease family	rbsC-2	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158397_k127_2665290_11	1379270.AUXF01000002_gene1216	1.145e-42	164.0	COG4603@1|root,COG4603@2|Bacteria,1ZTGR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158397_k127_2671414_0	518766.Rmar_0629	9.852e-274	877.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
SRR25158397_k127_2671414_6	330214.NIDE4157	6.66e-30	125.0	COG3824@1|root,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158397_k127_2671414_4	1407650.BAUB01000003_gene965	5.938e-155	509.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1H2SF@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158397_k127_2671414_5	1396141.BATP01000023_gene600	4.345e-65	233.0	COG0545@1|root,COG0545@2|Bacteria,46U5S@74201|Verrucomicrobia,2IVK3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
SRR25158397_k127_2671414_2	986075.CathTA2_2080	6.873e-209	657.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli	91061|Bacilli	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158397_k127_2671414_1	1227739.Hsw_3146	3.823e-212	671.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158397_k127_2671414_3	448385.sce8724	1.022e-168	546.0	COG3093@1|root,COG3800@1|root,COG3093@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,43B2B@68525|delta/epsilon subdivisions,2X6GC@28221|Deltaproteobacteria,2Z3AZ@29|Myxococcales	28221|Deltaproteobacteria	K	Pfam:DUF955	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
SRR25158397_k127_2677107_8	1122169.AREN01000014_gene2737	1.135e-61	218.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2677107_9	32049.SYNPCC7002_A2056	2.144e-51	194.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,1GZCJ@1129|Synechococcus	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRR25158397_k127_2677107_2	518766.Rmar_0536	2.269e-191	618.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1FIS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158397_k127_2677107_6	35754.JNYJ01000001_gene7520	4.165e-92	309.0	COG2755@1|root,COG2755@2|Bacteria,2GJUC@201174|Actinobacteria,4DI90@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158397_k127_2677107_7	441620.Mpop_1836	1.257e-69	251.0	COG4262@1|root,COG4262@2|Bacteria,1P1G3@1224|Proteobacteria,2TQSR@28211|Alphaproteobacteria,1JR09@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Spermidine synthase	MA20_16695	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158397_k127_2677107_10	861299.J421_1335	2.401e-50	192.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HD_5,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_2677107_5	861299.J421_1336	1.565e-131	423.0	COG0596@1|root,COG0596@2|Bacteria,1ZUIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_6
SRR25158397_k127_2677107_3	1384054.N790_03790	6.248e-178	582.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X2Z4@135614|Xanthomonadales	135614|Xanthomonadales	T	phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
SRR25158397_k127_2677107_11	666681.M301_0805	4.636e-48	179.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,2VSJJ@28216|Betaproteobacteria,2KMUS@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2677107_15	1336233.JAEH01000018_gene3100	1.04e-20	107.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria,2QAV5@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2677107_13	448385.sce1198	1.486e-38	152.0	COG3409@1|root,COG3409@2|Bacteria,1QEQE@1224|Proteobacteria,434PQ@68525|delta/epsilon subdivisions,2WZ0Y@28221|Deltaproteobacteria,2Z135@29|Myxococcales	28221|Deltaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158397_k127_2677107_1	1173025.GEI7407_2976	6.983e-196	636.0	COG0021@1|root,COG0021@2|Bacteria,1G0GC@1117|Cyanobacteria,1H7T2@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158397_k127_2677107_17	378806.STAUR_2955	7.902e-08	63.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SRR25158397_k127_2677107_16	1120954.ATXE01000002_gene980	3.586e-10	66.0	COG0664@1|root,COG0664@2|Bacteria,2IKTT@201174|Actinobacteria,4DVJ5@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_2677107_14	66875.JODY01000025_gene5780	1.513e-32	147.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria	201174|Actinobacteria	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158397_k127_2677107_0	1121382.JQKG01000006_gene3396	7.483e-223	718.0	2DUWA@1|root,33SPG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2677107_4	1499967.BAYZ01000013_gene6439	2.836e-175	576.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,GlcNAc_2-epim,Thioredox_DsbH
SRR25158397_k127_2677107_12	1336233.JAEH01000002_gene1346	4.738e-42	160.0	COG1225@1|root,COG1225@2|Bacteria,1QZW6@1224|Proteobacteria,1T4AY@1236|Gammaproteobacteria,2QD3D@267890|Shewanellaceae	1236|Gammaproteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158397_k127_27028_1	1144275.COCOR_02677	5.222e-89	310.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158397_k127_27028_0	56780.SYN_01564	1.402e-149	494.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MQ69@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158397_k127_271192_1	1125863.JAFN01000001_gene1693	4.019e-90	339.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158397_k127_271192_0	204669.Acid345_4396	2.265e-107	377.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158397_k127_2716966_5	1229781.C272_05769	1.561e-15	82.0	28MYG@1|root,2ZB5C@2|Bacteria,2H19V@201174|Actinobacteria,4FAQD@85019|Brevibacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2716966_0	582515.KR51_00029290	3.502e-82	294.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1G1FY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
SRR25158397_k127_2716966_1	300852.55771569	2.15e-53	202.0	COG0631@1|root,COG0631@2|Bacteria,1WIBX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158397_k127_2716966_3	420246.GTNG_2765	2.108e-34	150.0	COG0265@1|root,COG0265@2|Bacteria,1UYZJ@1239|Firmicutes,4HFHN@91061|Bacilli,1WHAK@129337|Geobacillus	91061|Bacilli	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158397_k127_2716966_6	436229.JOEH01000015_gene6032	6.696e-09	68.0	COG0654@1|root,COG1716@1|root,COG0654@2|Bacteria,COG1716@2|Bacteria,2I9P3@201174|Actinobacteria,2NKMN@228398|Streptacidiphilus	201174|Actinobacteria	CHT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158397_k127_2716966_4	397290.C810_03516	6.566e-17	88.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia,27MIP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158397_k127_2716966_2	357808.RoseRS_0666	2.978e-45	179.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158397_k127_2716966_7	502025.Hoch_3681	6.023e-07	54.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_2717184_0	1121920.AUAU01000013_gene1712	1.253e-113	397.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_2717184_1	1121920.AUAU01000013_gene1713	1.338e-106	362.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_2717184_2	1121920.AUAU01000013_gene1714	1.879e-93	321.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XR@57723|Acidobacteria	57723|Acidobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158397_k127_2717184_3	756067.MicvaDRAFT_4922	3.705e-09	65.0	COG0500@1|root,COG0500@2|Bacteria,1G1YB@1117|Cyanobacteria,1HA07@1150|Oscillatoriales	1117|Cyanobacteria	Q	Cyclopropane fatty acid synthase and related methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_2725654_8	1348635.BBJY01000002_gene3397	4.466e-24	116.0	COG4974@1|root,COG4974@2|Bacteria,1QV9T@1224|Proteobacteria,1T2UQ@1236|Gammaproteobacteria,1XWQA@135623|Vibrionales	135623|Vibrionales	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
SRR25158397_k127_2725654_3	1254432.SCE1572_34120	2.044e-101	364.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158397_k127_2725654_2	1121920.AUAU01000007_gene472	1.724e-221	727.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_2725654_6	240292.Ava_C0001	1.356e-93	321.0	COG0477@1|root,COG0477@2|Bacteria,1GHCR@1117|Cyanobacteria,1HKQS@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158397_k127_2725654_7	643473.KB235930_gene3020	8.145e-60	223.0	COG3208@1|root,COG3208@2|Bacteria,1G16V@1117|Cyanobacteria,1HIUI@1161|Nostocales	1117|Cyanobacteria	Q	thioesterase involved in non-ribosomal peptide biosynthesis	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
SRR25158397_k127_2725654_5	1144275.COCOR_03928	3.226e-96	331.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X7UA@28221|Deltaproteobacteria,2Z3KU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158397_k127_2725654_1	240292.Ava_1611	1.672e-221	723.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR25158397_k127_2725654_4	997346.HMPREF9374_3031	2.345e-101	368.0	COG2175@1|root,COG2175@2|Bacteria,1TT09@1239|Firmicutes,4HB8F@91061|Bacilli	91061|Bacilli	Q	Taurine catabolism dioxygenase TauD	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158397_k127_2725654_0	1144275.COCOR_04396	0.0	1562.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X9RA@28221|Deltaproteobacteria,2YXVT@29|Myxococcales	28221|Deltaproteobacteria	IQ	Non-ribosomal peptide	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,PP-binding
SRR25158397_k127_2725654_10	1121920.AUAU01000028_gene1384	0.0002768	48.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	2|Bacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
SRR25158397_k127_2725654_11	345341.KUTG_05115	0.0003206	49.0	COG3173@1|root,COG3173@2|Bacteria,2HNAP@201174|Actinobacteria,4E64G@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	ko:K06979	-	M00760	-	-	br01600,ko00000,ko00002,ko01504	-	-	-	APH
SRR25158397_k127_2733131_2	867903.ThesuDRAFT_00376	5.539e-44	172.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
SRR25158397_k127_2733131_0	861299.J421_4207	6.32e-145	492.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_2733131_1	251221.35210713	2.618e-52	202.0	COG3191@1|root,COG3191@2|Bacteria,1GR11@1117|Cyanobacteria	2|Bacteria	EQ	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRR25158397_k127_2735392_1	1192034.CAP_5423	1.922e-146	472.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158397_k127_2735392_3	497965.Cyan7822_3721	4.306e-35	143.0	COG3652@1|root,COG3652@2|Bacteria,1GJH1@1117|Cyanobacteria,3KK9R@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRR25158397_k127_2735392_2	383372.Rcas_3081	5.557e-109	358.0	COG0479@1|root,COG0479@2|Bacteria,2GACG@200795|Chloroflexi,3758X@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158397_k127_2735392_0	383372.Rcas_3080	3.405e-175	554.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158397_k127_273851_10	945713.IALB_3122	2.9e-34	138.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158397_k127_273851_6	234267.Acid_7247	6.271e-53	198.0	COG1595@1|root,COG1595@2|Bacteria,3Y815@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_273851_9	234267.Acid_7246	1.958e-37	157.0	2BI39@1|root,32C8D@2|Bacteria,3Y85Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_273851_4	639030.JHVA01000001_gene1848	3.273e-81	292.0	COG1413@1|root,COG1413@2|Bacteria,3Y7PB@57723|Acidobacteria	57723|Acidobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158397_k127_273851_11	278963.ATWD01000001_gene2878	2.459e-21	103.0	COG1413@1|root,COG1413@2|Bacteria,3Y76M@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158397_k127_273851_2	1227739.Hsw_2638	4.205e-89	310.0	COG5000@1|root,COG5000@2|Bacteria,4NFQN@976|Bacteroidetes,47KW9@768503|Cytophagia	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8
SRR25158397_k127_273851_0	1358423.N180_17725	9.916e-150	486.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1INPQ@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_273851_5	1198452.Jab_1c20610	2.976e-59	229.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_273851_3	1121015.N789_12935	2.373e-87	304.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_273851_1	504472.Slin_2350	2.58e-95	317.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47N2Z@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	ytrE_3	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_273851_7	1121957.ATVL01000007_gene1588	9.814e-50	193.0	COG0845@1|root,COG0845@2|Bacteria,4NIJI@976|Bacteroidetes,47KW8@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158397_k127_273851_8	313606.M23134_04078	1.866e-38	146.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,47Q3H@768503|Cytophagia	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18,HTH_AraC
SRR25158397_k127_2741789_1	903818.KI912268_gene2000	2.791e-32	136.0	COG0745@1|root,COG0745@2|Bacteria	903818.KI912268_gene2000|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2741789_3	243232.MJ_1492	1.589e-16	92.0	COG3815@1|root,arCOG03949@2157|Archaea,2XYKM@28890|Euryarchaeota,23R0V@183939|Methanococci	183939|Methanococci	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
SRR25158397_k127_2741789_2	479434.Sthe_1708	2.164e-22	110.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SRR25158397_k127_2741789_5	234267.Acid_6206	1.544e-06	61.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
SRR25158397_k127_2741789_4	1444306.JFZC01000012_gene2040	2.132e-07	59.0	COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli	91061|Bacilli	V	VanZ like family	vanZ	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158397_k127_2741789_0	118163.Ple7327_1968	2.602e-62	232.0	COG2931@1|root,COG2931@2|Bacteria,1GHAU@1117|Cyanobacteria,3VMMX@52604|Pleurocapsales	1117|Cyanobacteria	Q	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158397_k127_2747825_0	1242864.D187_004919	7.849e-168	533.0	COG0174@1|root,COG0174@2|Bacteria,1NZU7@1224|Proteobacteria	1224|Proteobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158397_k127_2747825_2	1125863.JAFN01000001_gene3329	1.643e-52	202.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158397_k127_2747825_6	172045.KS04_07325	1.688e-05	53.0	2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,1I3WH@117743|Flavobacteriia,34RT1@308865|Elizabethkingia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2747825_1	1267534.KB906754_gene3465	2.651e-101	337.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria,2JM9F@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158397_k127_2747825_4	290397.Adeh_4019	3.446e-32	138.0	COG2050@1|root,COG2050@2|Bacteria,1RKGI@1224|Proteobacteria,42WI1@68525|delta/epsilon subdivisions,2WSAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
SRR25158397_k127_2747825_3	62928.azo0383	1.779e-47	179.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,2KZNP@206389|Rhodocyclales	206389|Rhodocyclales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158397_k127_2747825_5	1192034.CAP_3960	3.959e-24	115.0	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,43ACX@68525|delta/epsilon subdivisions,2X5SX@28221|Deltaproteobacteria	1224|Proteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_2767518_0	1122138.AQUZ01000065_gene4276	2.042e-300	948.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4DN78@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
SRR25158397_k127_2767518_1	330214.NIDE3382	2.951e-36	152.0	2ECCV@1|root,336B4@2|Bacteria,3J18G@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_27683_0	264462.Bd2634	6.331e-238	756.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,43C3C@68525|delta/epsilon subdivisions,2MTI8@213481|Bdellovibrionales,2X7DZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Xanthine dehydrogenase	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158397_k127_27683_2	1190606.AJYG01000197_gene4337	3.812e-65	232.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XUPI@135623|Vibrionales	135623|Vibrionales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158397_k127_27683_1	378806.STAUR_1028	6.385e-154	497.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria,437FH@68525|delta/epsilon subdivisions,2X2N4@28221|Deltaproteobacteria,2YTXN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158397_k127_2768398_0	326427.Cagg_2093	4.499e-262	833.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,3768X@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SRR25158397_k127_2768398_2	1198452.Jab_2c00350	7.888e-95	319.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria,2VNVR@28216|Betaproteobacteria,47618@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	RsbT co-antagonist protein rsbRD N-terminal domain	rsbRA	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
SRR25158397_k127_2768398_5	1500897.JQNA01000002_gene2769	5.676e-51	183.0	COG1366@1|root,COG1366@2|Bacteria,1RJM8@1224|Proteobacteria,2VT28@28216|Betaproteobacteria,1K7XA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158397_k127_2768398_4	63737.Npun_R2265	4.626e-53	190.0	COG2172@1|root,COG2172@2|Bacteria,1G668@1117|Cyanobacteria,1HQ42@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c
SRR25158397_k127_2768398_3	221288.JH992901_gene1439	2.681e-70	255.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,1G02S@1117|Cyanobacteria	1117|Cyanobacteria	KT	PFAM Stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
SRR25158397_k127_2768398_1	1173027.Mic7113_3985	7.073e-163	530.0	COG0642@1|root,COG0745@1|root,COG2172@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2205@2|Bacteria,1G2CJ@1117|Cyanobacteria,1H91Z@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158397_k127_2768398_7	1216932.CM240_0451	1.739e-09	68.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia,36GMR@31979|Clostridiaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_2768398_6	172045.KS04_10650	3.443e-15	79.0	COG0454@1|root,COG0456@2|Bacteria,4NKGU@976|Bacteroidetes,1HZFA@117743|Flavobacteriia,34PZN@308865|Elizabethkingia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158397_k127_2776785_3	237368.SCABRO_00310	2.462e-80	289.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158397_k127_2776785_4	1210884.HG799465_gene11383	2.136e-49	188.0	COG1234@1|root,COG1234@2|Bacteria,2IWSW@203682|Planctomycetes	203682|Planctomycetes	S	of the beta-lactamase	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158397_k127_2776785_6	304371.MCP_2958	4.023e-29	126.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158397_k127_2776785_8	637390.AFOH01000036_gene1447	1.799e-20	94.0	COG4911@1|root,COG4911@2|Bacteria,1NPJ8@1224|Proteobacteria,1T8JU@1236|Gammaproteobacteria,2ND17@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158397_k127_2776785_7	882.DVU_1205	1.453e-24	106.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2MCPM@213115|Desulfovibrionales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158397_k127_2776785_0	1499967.BAYZ01000055_gene4866	1.05e-170	547.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_2776785_1	867903.ThesuDRAFT_01903	2.022e-108	363.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia	186801|Clostridia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
SRR25158397_k127_2776785_5	234267.Acid_7343	3.926e-40	156.0	COG0666@1|root,COG0666@2|Bacteria,3Y86V@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3
SRR25158397_k127_2776785_2	861299.J421_3700	1.716e-86	301.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158397_k127_2776971_1	269797.Mbar_A0810	1.065e-59	229.0	COG3291@1|root,COG3391@1|root,arCOG03991@1|root,arCOG02508@2157|Archaea,arCOG02562@2157|Archaea,arCOG03991@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158397_k127_2776971_5	1125863.JAFN01000001_gene829	7.736e-30	138.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
SRR25158397_k127_2776971_0	682795.AciX8_4273	7.178e-105	371.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria,2JK1Q@204432|Acidobacteriia	204432|Acidobacteriia	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158397_k127_2776971_6	234267.Acid_2588	1.818e-10	70.0	290DP@1|root,2ZN31@2|Bacteria,3Y8WY@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158397_k127_2776971_4	1382359.JIAL01000001_gene404	4.696e-42	161.0	COG1595@1|root,COG1595@2|Bacteria,3Y87A@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158397_k127_2776971_8	1267535.KB906767_gene3274	7.049e-10	66.0	2CIIF@1|root,30NI8@2|Bacteria,3Y8FJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2776971_3	378753.KRH_03170	9.636e-46	169.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,1W96T@1268|Micrococcaceae	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158397_k127_2776971_7	1408418.JNJH01000020_gene967	2.734e-10	64.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2JV8U@204441|Rhodospirillales	204441|Rhodospirillales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158397_k127_2776971_2	1123371.ATXH01000003_gene1880	6.92e-53	189.0	COG2812@1|root,COG2812@2|Bacteria,2GH2B@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158397_k127_2787733_3	204669.Acid345_0365	2.097e-58	212.0	COG2846@1|root,COG2846@2|Bacteria,3Y4SU@57723|Acidobacteria,2JMU3@204432|Acidobacteriia	204432|Acidobacteriia	D	Domain of Unknown function (DUF542)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SRR25158397_k127_2787733_0	204669.Acid345_0364	0.0	1101.0	COG3256@1|root,COG3256@2|Bacteria,3Y2GQ@57723|Acidobacteria,2JKWD@204432|Acidobacteriia	204432|Acidobacteriia	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SRR25158397_k127_2787733_2	234267.Acid_7897	1.961e-142	477.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2787733_4	1340493.JNIF01000003_gene1664	3.369e-53	203.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SRR25158397_k127_2787733_5	234267.Acid_6725	5.074e-06	60.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2787733_1	1121898.Q766_12730	3.747e-189	606.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1HXFG@117743|Flavobacteriia,2NV9I@237|Flavobacterium	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
SRR25158397_k127_2792547_0	1382306.JNIM01000001_gene3093	4.479e-118	393.0	COG0318@1|root,COG0318@2|Bacteria,2G5K4@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158397_k127_2792547_4	990285.RGCCGE502_25053	9.691e-11	72.0	COG1309@1|root,COG1309@2|Bacteria,1RDE7@1224|Proteobacteria,2UAIU@28211|Alphaproteobacteria,4BM7J@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158397_k127_2792547_3	1047013.AQSP01000103_gene1162	2.382e-16	93.0	2E93F@1|root,333CD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2792547_5	118173.KB235914_gene3941	6.255e-08	66.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158397_k127_2792547_1	861299.J421_1461	5.042e-42	177.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
SRR25158397_k127_2792547_2	886293.Sinac_6279	1.089e-40	154.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158397_k127_2811139_1	452637.Oter_4609	1.461e-109	361.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158397_k127_2811139_0	309807.SRU_0449	6.191e-256	818.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1FJ58@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
SRR25158397_k127_2811139_2	1121405.dsmv_3719	5.344e-65	237.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2MI64@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158397_k127_2811139_3	717605.Theco_1887	1.01e-64	231.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,26QG6@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158397_k127_2828040_2	338966.Ppro_0084	1.942e-68	267.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43T8P@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
SRR25158397_k127_2828040_4	1267534.KB906759_gene1765	1.809e-49	186.0	COG3279@1|root,COG3279@2|Bacteria,3Y7UE@57723|Acidobacteria,2JP1S@204432|Acidobacteriia	204432|Acidobacteriia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158397_k127_2828040_7	309807.SRU_2326	4.577e-12	77.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1FIPJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158397_k127_2828040_5	1384054.N790_02955	4.505e-38	162.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_2828040_3	1463900.JOIX01000013_gene3440	1.252e-53	192.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158397_k127_2828040_8	1382230.ASAP_1639	1.678e-09	63.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158397_k127_2828040_1	1197906.CAJQ02000009_gene3633	1.72e-69	242.0	COG0640@1|root,COG0640@2|Bacteria,1MWCW@1224|Proteobacteria,2TTA5@28211|Alphaproteobacteria,3JRUF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	ydfF	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158397_k127_2828040_6	314278.NB231_15718	1.085e-34	135.0	COG2963@1|root,COG2963@2|Bacteria,1N8Y3@1224|Proteobacteria	1224|Proteobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158397_k127_2828040_0	246197.MXAN_1715	1.966e-109	364.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
SRR25158397_k127_2829941_7	1123376.AUIU01000011_gene928	9.162e-28	115.0	COG1624@1|root,COG1624@2|Bacteria,3J0XP@40117|Nitrospirae	40117|Nitrospirae	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158397_k127_2829941_8	871968.DESME_02465	7.516e-11	71.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,2612S@186807|Peptococcaceae	186801|Clostridia	S	PFAM YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158397_k127_2829941_1	1267534.KB906759_gene1844	7.374e-110	376.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158397_k127_2829941_4	240292.Ava_3338	3.146e-74	258.0	COG1028@1|root,COG1028@2|Bacteria,1G2FK@1117|Cyanobacteria,1HMHE@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.206	ko:K08081	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R02832	RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158397_k127_2829941_0	1521187.JPIM01000007_gene1422	0.0	1332.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,375DP@32061|Chloroflexia	32061|Chloroflexia	F	Carbamoyl-phosphate synthetase large chain domain protein	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158397_k127_2829941_6	1408254.T458_19155	1.526e-35	142.0	COG3339@1|root,COG3339@2|Bacteria,1V6NW@1239|Firmicutes,4HJQR@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158397_k127_2829941_5	240015.ACP_1095	1.493e-40	154.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158397_k127_2829941_3	243231.GSU3077	2.188e-83	287.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,43TQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158397_k127_2829941_9	240015.ACP_1093	1.443e-05	53.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria,2JJBJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
SRR25158397_k127_2829941_2	316067.Geob_0774	2.57e-107	370.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158397_k127_2833757_3	196164.23494323	4.37e-29	123.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,22JPQ@1653|Corynebacteriaceae	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158397_k127_2833757_2	1395587.P364_0113550	7.067e-44	167.0	COG1670@1|root,COG1670@2|Bacteria,1V54D@1239|Firmicutes,4HIQW@91061|Bacilli,26Y91@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158397_k127_2833757_4	1279009.ADICEAN_02097	1.116e-26	124.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2833757_1	204669.Acid345_2219	4.992e-94	340.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y9GC@57723|Acidobacteria,2JKTW@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158397_k127_2833757_0	215803.DB30_7774	3.981e-194	615.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42PKM@68525|delta/epsilon subdivisions,2WJCP@28221|Deltaproteobacteria,2YUCG@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158397_k127_2839055_1	861299.J421_4439	4.25e-68	248.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_4439|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158397_k127_2839055_0	215803.DB30_7721	4.63e-119	406.0	COG2911@1|root,COG3055@1|root,COG2911@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
SRR25158397_k127_2839055_5	1118059.CAHC01000012_gene342	5.349e-07	59.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WCU7@538999|Clostridiales incertae sedis	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_2839055_4	43759.JNWK01000009_gene4881	3.34e-12	75.0	COG2304@1|root,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
SRR25158397_k127_2839055_6	215803.DB30_8858	1.157e-06	61.0	2BQYU@1|root,32JW3@2|Bacteria,1Q2HP@1224|Proteobacteria,4384I@68525|delta/epsilon subdivisions,2X3EG@28221|Deltaproteobacteria,2YVQ8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2839055_3	861299.J421_0577	1.292e-19	102.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1ZV5J@142182|Gemmatimonadetes	2|Bacteria	O	Subtilase family	-	-	3.2.1.14,3.4.21.50	ko:K01183,ko:K01337,ko:K14645	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH18	-	Inhibitor_I9,PKD,PPC,P_proprotein,Peptidase_M14,Peptidase_S8
SRR25158397_k127_2839055_2	357808.RoseRS_1682	7.504e-24	117.0	COG3209@1|root,COG3209@2|Bacteria,2G6KZ@200795|Chloroflexi	200795|Chloroflexi	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB
SRR25158397_k127_2850069_2	1384054.N790_02955	6.685e-57	203.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_2850069_1	1384054.N790_02960	1.199e-94	325.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158397_k127_2850069_4	180332.JTGN01000001_gene4690	1.82e-09	70.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia	186801|Clostridia	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
SRR25158397_k127_2850069_3	408672.NBCG_04152	1.118e-33	145.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4DQNK@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158397_k127_2850069_0	1267535.KB906767_gene2599	3.411e-96	326.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JMQ0@204432|Acidobacteriia	204432|Acidobacteriia	F	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158397_k127_2851561_1	1047013.AQSP01000135_gene1588	8.655e-24	109.0	COG2980@1|root,COG2980@2|Bacteria	2|Bacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
SRR25158397_k127_2851561_0	391009.Tmel_0256	8.857e-286	900.0	COG0495@1|root,COG0495@2|Bacteria,2GC3Z@200918|Thermotogae	200918|Thermotogae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158397_k127_2862249_15	1144275.COCOR_03283	9.598e-20	103.0	2EBW1@1|root,335VE@2|Bacteria,1NPNE@1224|Proteobacteria,432H3@68525|delta/epsilon subdivisions,2WXS6@28221|Deltaproteobacteria,2Z25U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2862249_16	644282.Deba_2252	7.222e-07	60.0	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions,2WR43@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2862249_12	1196083.SALWKB12_1204	9.089e-24	108.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KPPX@206351|Neisseriales	206351|Neisseriales	Q	Type I secretion target GGXGXDXXX repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158397_k127_2862249_0	555079.Toce_1427	9.526e-157	514.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158397_k127_2862249_11	1379270.AUXF01000003_gene3432	4.4e-31	141.0	COG0662@1|root,COG0662@2|Bacteria,1ZTKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158397_k127_2862249_4	86416.Clopa_2664	3.171e-110	378.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,36DJV@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158397_k127_2862249_9	671143.DAMO_1375	3.379e-47	182.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
SRR25158397_k127_2862249_3	1300345.LF41_2983	2.058e-114	388.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Cellulase,NHL,RicinB_lectin_2
SRR25158397_k127_2862249_5	1047013.AQSP01000134_gene1378	8.737e-87	295.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158397_k127_2862249_10	1122214.AQWH01000012_gene3848	6.561e-33	145.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,2PJJW@255475|Aurantimonadaceae	28211|Alphaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158397_k127_2862249_14	1396141.BATP01000023_gene616	1.076e-21	105.0	2B5SN@1|root,31YNB@2|Bacteria,46XHC@74201|Verrucomicrobia,2IVXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2862249_13	1396141.BATP01000023_gene615	7.157e-22	107.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2862249_1	748280.NH8B_0055	3.028e-145	471.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,2KQFQ@206351|Neisseriales	206351|Neisseriales	E	Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158397_k127_2862249_8	335543.Sfum_1218	5.976e-69	254.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,2MQ61@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158397_k127_2862249_2	1198114.AciX9_1751	3.086e-119	414.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
SRR25158397_k127_2862249_6	391625.PPSIR1_25986	3.636e-84	310.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169,iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
SRR25158397_k127_2862249_7	926549.KI421517_gene3452	6.883e-81	281.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,47K82@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158397_k127_2870382_11	222534.KB893740_gene1541	1.414e-28	133.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria	201174|Actinobacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR25158397_k127_2870382_8	945543.VIBR0546_12882	3.471e-64	228.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,1XV0Z@135623|Vibrionales	135623|Vibrionales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158397_k127_2870382_14	1089547.KB913013_gene3085	6.474e-20	93.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
SRR25158397_k127_2870382_3	888060.HMPREF9081_1234	3.629e-135	443.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4H39S@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158397_k127_2870382_7	1157490.EL26_23860	3.783e-74	278.0	COG3511@1|root,COG3511@2|Bacteria,1VJCE@1239|Firmicutes,4IRFQ@91061|Bacilli	91061|Bacilli	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158397_k127_2870382_9	338963.Pcar_0454	5.166e-56	219.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2WKAH@28221|Deltaproteobacteria,43TV7@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_2870382_4	861299.J421_0736	1.74e-103	351.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_2870382_2	1267535.KB906767_gene322	3.974e-138	463.0	COG1228@1|root,COG1228@2|Bacteria,3Y6Y2@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_2870382_5	861299.J421_0738	1.115e-80	297.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158397_k127_2870382_6	903818.KI912268_gene2060	1.067e-74	282.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
SRR25158397_k127_2870382_16	926566.Terro_3228	0.0005558	53.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158397_k127_2870382_1	1144275.COCOR_01562	1.017e-141	466.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2YUKT@29|Myxococcales	28221|Deltaproteobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158397_k127_2870382_13	449447.MAE_44440	7.19e-24	109.0	COG3729@1|root,COG3729@2|Bacteria,1G86R@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
SRR25158397_k127_2870382_10	1123276.KB893258_gene2892	8.793e-42	157.0	COG4244@1|root,COG4244@2|Bacteria,4NPHV@976|Bacteroidetes,47PWW@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158397_k127_2870382_0	525904.Tter_2125	0.0	1163.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2NQGX@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158397_k127_2870382_12	1121481.AUAS01000015_gene2257	1.583e-26	116.0	2E36Z@1|root,32Y6R@2|Bacteria,4NV8U@976|Bacteroidetes,47SBT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2877168_2	190650.CC_1502	7.948e-78	279.0	COG1680@1|root,COG1680@2|Bacteria,1RHDA@1224|Proteobacteria,2VEYX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_2877168_1	1040989.AWZU01000001_gene5816	9.623e-105	357.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,3JUPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158397_k127_2877168_0	1267534.KB906756_gene683	1.338e-117	386.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	ko:K03420,ko:K13525,ko:K17681	ko03050,ko04141,ko05134,map03050,map04141,map05134	M00343,M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko03029,ko03051,ko04131,ko04147	3.A.16.1	-	-	AAA
SRR25158397_k127_2886530_2	1286093.C266_07815	2.29e-26	127.0	COG4258@1|root,COG4258@2|Bacteria,1QTXZ@1224|Proteobacteria,2VM6Q@28216|Betaproteobacteria,1K12F@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN	hpnN	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158397_k127_2886530_0	640081.Dsui_3298	1.974e-229	726.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2VHSM@28216|Betaproteobacteria,2KVUD@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158397_k127_2886530_1	671143.DAMO_3051	1.192e-31	127.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158397_k127_2886530_3	1173029.JH980292_gene550	2.101e-21	98.0	COG1669@1|root,COG1669@2|Bacteria,1G804@1117|Cyanobacteria,1HCHE@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_2907186_2	204669.Acid345_2529	2.684e-60	214.0	COG1030@1|root,COG1030@2|Bacteria,3Y31N@57723|Acidobacteria,2JHS7@204432|Acidobacteriia	204432|Acidobacteriia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158397_k127_2907186_3	1178825.ALIH01000010_gene445	2.687e-48	187.0	COG1216@1|root,COG1216@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
SRR25158397_k127_2907186_5	543632.JOJL01000013_gene9358	2.977e-15	90.0	COG1971@1|root,COG1971@2|Bacteria,2GUWT@201174|Actinobacteria,4DAJ1@85008|Micromonosporales	201174|Actinobacteria	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2907186_0	204669.Acid345_3211	2.121e-164	540.0	COG1228@1|root,COG1228@2|Bacteria,3Y32S@57723|Acidobacteria,2JIA1@204432|Acidobacteriia	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_2907186_4	862908.BMS_1887	3.449e-47	180.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
SRR25158397_k127_2907186_1	404589.Anae109_1724	1.669e-95	322.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158397_k127_2922250_10	56780.SYN_00437	1.56e-25	112.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MQ7W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158397_k127_2922250_12	269798.CHU_2693	0.0004955	52.0	2FD8R@1|root,345AR@2|Bacteria,4P5VE@976|Bacteroidetes,47VZT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2922250_9	572480.Arnit_2948	8.316e-36	149.0	COG0399@1|root,COG0399@2|Bacteria,1NWV9@1224|Proteobacteria,43056@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2922250_8	375451.RD1_0572	4.261e-43	173.0	2DR9T@1|root,33ATT@2|Bacteria	2|Bacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158397_k127_2922250_0	926550.CLDAP_18760	1.718e-260	812.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158397_k127_2922250_4	1454004.AW11_02186	3.64e-94	317.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,2VXD0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
SRR25158397_k127_2922250_5	153721.MYP_1249	8.489e-76	265.0	COG0463@1|root,COG0463@2|Bacteria,4NKQ4@976|Bacteroidetes,47KJW@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SRR25158397_k127_2922250_2	926569.ANT_20160	1.518e-160	520.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	wecE	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089	DegT_DnrJ_EryC1
SRR25158397_k127_2922250_7	1123072.AUDH01000005_gene1667	1.793e-43	167.0	COG0500@1|root,COG2226@2|Bacteria,1PTQA@1224|Proteobacteria,2V5JE@28211|Alphaproteobacteria,2JYCV@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2922250_6	1121899.Q764_09775	4.143e-49	189.0	COG2227@1|root,COG2227@2|Bacteria,4PPMA@976|Bacteroidetes,1IKR2@117743|Flavobacteriia,2NXJE@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_2922250_11	1122176.KB903536_gene1853	4.483e-15	89.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF4347,He_PIG,PATR,SLH
SRR25158397_k127_2922250_3	335543.Sfum_1625	6.032e-105	363.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SRR25158397_k127_2922250_1	1158345.JNLL01000001_gene818	2.605e-203	644.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G3NT@200783|Aquificae	200783|Aquificae	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158397_k127_2930971_4	243231.GSU1433	9.238e-78	280.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43U0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158397_k127_2930971_3	344747.PM8797T_29063	8.018e-79	276.0	COG0601@1|root,COG0601@2|Bacteria,2IYGR@203682|Planctomycetes	203682|Planctomycetes	P	transport systems	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158397_k127_2930971_2	880072.Desac_2878	1.311e-79	290.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158397_k127_2930971_7	278963.ATWD01000001_gene2098	1.249e-55	200.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158397_k127_2930971_5	1125863.JAFN01000001_gene236	1.164e-74	270.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158397_k127_2930971_6	871968.DESME_05910	1.782e-56	202.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,24HUX@186801|Clostridia,261V6@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158397_k127_2930971_10	204669.Acid345_1574	1.859e-12	76.0	COG2834@1|root,COG2834@2|Bacteria,3Y4XE@57723|Acidobacteria,2JJK4@204432|Acidobacteriia	204432|Acidobacteriia	M	outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
SRR25158397_k127_2930971_9	1121920.AUAU01000030_gene2713	1.514e-13	75.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2930971_1	338966.Ppro_0969	2.428e-98	346.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43SXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
SRR25158397_k127_2930971_0	383372.Rcas_0858	3.101e-102	342.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158397_k127_2930971_8	760192.Halhy_4503	1.852e-17	89.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SRR25158397_k127_2932886_1	765913.ThidrDRAFT_0643	2.795e-79	285.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WVXQ@135613|Chromatiales	135613|Chromatiales	O	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158397_k127_2932886_2	765913.ThidrDRAFT_0644	1.008e-68	248.0	COG1672@1|root,COG1672@2|Bacteria,1R8WY@1224|Proteobacteria,1S0C0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_2932886_0	1254432.SCE1572_10345	0.0	1046.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158397_k127_29357_5	525257.HMPREF0204_14247	7.063e-23	100.0	COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes,1I32M@117743|Flavobacteriia,3ZR86@59732|Chryseobacterium	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_29357_4	272134.KB731324_gene6103	1.624e-26	109.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,1HCJ2@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_29357_1	234267.Acid_6299	3.971e-68	242.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
SRR25158397_k127_29357_8	1123240.ATVO01000003_gene465	0.0008164	48.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158397_k127_29357_3	234267.Acid_7833	3.048e-56	205.0	COG1309@1|root,COG1309@2|Bacteria,3Y4QT@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158397_k127_29357_0	204669.Acid345_0624	1.734e-110	366.0	COG1090@1|root,COG1090@2|Bacteria,3Y2PB@57723|Acidobacteria,2JI82@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158397_k127_29357_6	1165096.ARWF01000001_gene318	1.975e-17	89.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria,2KN3G@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158397_k127_29357_2	1131269.AQVV01000014_gene208	1.471e-60	215.0	COG1949@1|root,COG1949@2|Bacteria	2|Bacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158397_k127_29357_7	1121920.AUAU01000014_gene2821	1.531e-11	74.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_2940846_0	1183438.GKIL_4354	7.815e-181	604.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158397_k127_2940846_2	234267.Acid_6481	1.487e-104	364.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_2940846_3	1183438.GKIL_2517	1.072e-99	342.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158397_k127_2940846_1	1379698.RBG1_1C00001G1660	9.137e-111	374.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
SRR25158397_k127_2940846_5	643473.KB235931_gene4855	1.307e-11	72.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_2940846_4	756499.Desde_0863	1.846e-19	91.0	COG2050@1|root,COG2050@2|Bacteria,1VXYK@1239|Firmicutes,251HM@186801|Clostridia	186801|Clostridia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158397_k127_294289_0	321327.CYA_2836	1.302e-146	496.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1GYFK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_294289_5	1118235.CAJH01000024_gene1724	5.752e-12	77.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1X5IQ@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
SRR25158397_k127_294289_4	649743.HMPREF0972_01244	2.934e-14	81.0	COG0745@1|root,COG0745@2|Bacteria,2H3IN@201174|Actinobacteria,4D4WZ@85005|Actinomycetales	201174|Actinobacteria	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_294289_3	56110.Oscil6304_1390	6.484e-15	80.0	COG0745@1|root,COG0745@2|Bacteria,1G027@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
SRR25158397_k127_294289_1	290397.Adeh_0837	1.177e-53	198.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_294289_2	1267533.KB906735_gene4867	1.177e-51	195.0	COG3391@1|root,COG3391@2|Bacteria,3Y2SU@57723|Acidobacteria,2JKB8@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158397_k127_2995131_1	1128421.JAGA01000003_gene2923	2.965e-127	422.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158397_k127_2995131_8	1128421.JAGA01000003_gene2924	1.174e-60	217.0	2CAZH@1|root,2Z7RU@2|Bacteria,2NRIS@2323|unclassified Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158397_k127_2995131_3	234267.Acid_1275	5.934e-89	299.0	COG1131@1|root,COG1131@2|Bacteria,3Y3PI@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_2995131_9	306281.AJLK01000102_gene3414	3.674e-56	208.0	COG0604@1|root,COG0604@2|Bacteria,1G3UU@1117|Cyanobacteria,1JK4N@1189|Stigonemataceae	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158397_k127_2995131_6	926560.KE387026_gene4175	5.696e-84	285.0	COG0842@1|root,COG0842@2|Bacteria,1WM4H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158397_k127_2995131_7	234267.Acid_1273	8.89e-82	284.0	COG4585@1|root,COG4585@2|Bacteria,3Y42D@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158397_k127_2995131_4	926560.KE387026_gene4177	4.558e-88	296.0	COG2197@1|root,COG2197@2|Bacteria,1WM1U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158397_k127_2995131_5	1242864.D187_004923	2.405e-85	308.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YWC2@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158397_k127_2995131_14	1121430.JMLG01000002_gene1042	2.612e-05	55.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,266Z7@186807|Peptococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
SRR25158397_k127_2995131_13	263358.VAB18032_20110	1.069e-07	63.0	COG5401@1|root,COG5401@2|Bacteria,2IK3M@201174|Actinobacteria,4DDDD@85008|Micromonosporales	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158397_k127_2995131_12	1094508.Tsac_0303	1.276e-08	67.0	COG4733@1|root,COG4733@2|Bacteria,1TT7S@1239|Firmicutes,24EIJ@186801|Clostridia,42FI7@68295|Thermoanaerobacterales	186801|Clostridia	S	Cell surface receptor IPT TIG	-	-	-	-	-	-	-	-	-	-	-	-	TIG,fn3
SRR25158397_k127_2995131_0	1349820.M707_05730	9.362e-214	680.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,1W7GS@1268|Micrococcaceae	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158397_k127_2995131_11	1121918.ARWE01000001_gene2006	2.306e-47	184.0	COG0330@1|root,COG0330@2|Bacteria,1R8RD@1224|Proteobacteria,42QFB@68525|delta/epsilon subdivisions,2WJQE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158397_k127_2995131_10	1232437.KL661988_gene306	5.349e-56	209.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2WK2W@28221|Deltaproteobacteria,2MMS8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158397_k127_2995131_2	661478.OP10G_4087	4.402e-104	351.0	COG1301@1|root,COG1301@2|Bacteria	2|Bacteria	C	dicarboxylic acid transport	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
SRR25158397_k127_2996617_8	706434.HMPREF9429_01555	9.92e-21	105.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H3NI@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158397_k127_2996617_7	795666.MW7_0778	1.349e-25	115.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,1KCBP@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158397_k127_2996617_5	1379270.AUXF01000002_gene1799	3.539e-32	138.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158397_k127_2996617_4	382464.ABSI01000016_gene745	1.28e-40	156.0	COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,2IUPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158397_k127_2996617_1	710421.Mycch_2966	4.067e-99	336.0	COG1752@1|root,COG1752@2|Bacteria,2I9XW@201174|Actinobacteria,236GN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158397_k127_2996617_3	483219.LILAB_32755	3.349e-62	228.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158397_k127_2996617_9	492774.JQMB01000002_gene807	3.211e-17	95.0	COG3153@1|root,COG3153@2|Bacteria,1QU4W@1224|Proteobacteria,2TVZP@28211|Alphaproteobacteria,4B7P6@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158397_k127_2996617_6	1173022.Cri9333_3153	1.781e-26	125.0	COG0671@1|root,COG0671@2|Bacteria,1G5BI@1117|Cyanobacteria,1HAHT@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158397_k127_2996617_0	945713.IALB_1242	0.0	1025.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria	2|Bacteria	C	oxoglutarate dehydrogenase (succinyl-transferring) activity	sucA	GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158397_k127_3006910_1	861299.J421_0739	1.334e-156	503.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
SRR25158397_k127_3006910_0	518766.Rmar_0089	0.0	1109.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_3006910_2	1380394.JADL01000003_gene5164	1.557e-51	186.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SRR25158397_k127_3019414_5	682795.AciX8_0601	1.503e-28	123.0	COG2095@1|root,COG2095@2|Bacteria,3Y429@57723|Acidobacteria,2JI6F@204432|Acidobacteriia	204432|Acidobacteriia	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158397_k127_3019414_0	204669.Acid345_1150	2.892e-68	238.0	arCOG09454@1|root,31B41@2|Bacteria,3Y8HD@57723|Acidobacteria,2JNG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3019414_3	626522.GCWU000325_01099	7.198e-57	217.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,2FMGJ@200643|Bacteroidia,1WCPZ@1283313|Alloprevotella	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158397_k127_3019414_4	1128421.JAGA01000002_gene410	1.441e-33	134.0	COG0394@1|root,COG0394@2|Bacteria,2NPGV@2323|unclassified Bacteria	2|Bacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158397_k127_3019414_2	861299.J421_3958	4.427e-60	213.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
SRR25158397_k127_3019414_1	118163.Ple7327_3212	2.158e-67	234.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,3VJ47@52604|Pleurocapsales	1117|Cyanobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
SRR25158397_k127_3020780_5	1121920.AUAU01000019_gene2589	4.658e-18	100.0	COG1514@1|root,COG1514@2|Bacteria,3Y5S7@57723|Acidobacteria	57723|Acidobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158397_k127_3020780_3	1515746.HR45_11315	1.007e-65	255.0	COG3303@1|root,COG3303@2|Bacteria,1NNDS@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3020780_4	1242864.D187_000830	1.321e-21	104.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,4393M@68525|delta/epsilon subdivisions,2X49J@28221|Deltaproteobacteria,2YYJG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SRR25158397_k127_3020780_0	240015.ACP_1487	1.491e-151	492.0	COG1027@1|root,COG1027@2|Bacteria,3Y3XS@57723|Acidobacteria,2JHYF@204432|Acidobacteriia	204432|Acidobacteriia	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158397_k127_3020780_2	1201288.M900_A0014	4.609e-72	247.0	COG1838@1|root,COG1838@2|Bacteria,1R33Y@1224|Proteobacteria,43DIX@68525|delta/epsilon subdivisions,2MUNI@213481|Bdellovibrionales,2WK6Z@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
SRR25158397_k127_3020780_1	1353529.M899_0311	1.774e-111	369.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
SRR25158397_k127_3020780_6	251229.Chro_2277	1.246e-16	85.0	COG1487@1|root,COG1487@2|Bacteria,1G6XP@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158397_k127_3038343_0	886293.Sinac_1156	2.377e-266	861.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SRR25158397_k127_3038343_3	1125863.JAFN01000001_gene3142	1.755e-10	71.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2WSJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158397_k127_3038343_2	292415.Tbd_1534	1.558e-27	128.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,1KRDI@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_3038343_1	1441629.PCH70_08290	4.315e-44	171.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1Z6J5@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158397_k127_3038343_4	3067.XP_002956275.1	4.592e-08	62.0	COG0136@1|root,KOG4777@2759|Eukaryota,37QRJ@33090|Viridiplantae,34GQT@3041|Chlorophyta	3041|Chlorophyta	E	Semialdehyde dehydrogenase, NAD binding domain	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158397_k127_3043575_6	406818.XBJ1_3704	9.088e-09	59.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3043575_4	316055.RPE_4178	4.058e-22	109.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,3JTX8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
SRR25158397_k127_3043575_2	1267533.KB906735_gene5073	1.284e-47	189.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158397_k127_3043575_1	1379270.AUXF01000001_gene2349	9.094e-53	189.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
SRR25158397_k127_3043575_3	1210884.HG799462_gene7921	4.148e-25	112.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR25158397_k127_3043575_0	1254432.SCE1572_50070	1.223e-68	237.0	COG3093@1|root,COG3800@1|root,COG3093@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,43B2B@68525|delta/epsilon subdivisions,2X6GC@28221|Deltaproteobacteria,2Z3AZ@29|Myxococcales	28221|Deltaproteobacteria	K	Pfam:DUF955	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
SRR25158397_k127_3066005_2	1306174.JODP01000010_gene6934	4.06e-35	137.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria	201174|Actinobacteria	P	Arsenical pump membrane protein	arsA	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
SRR25158397_k127_3066005_1	204669.Acid345_1498	5.867e-62	232.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_3066005_0	404380.Gbem_3081	4.628e-117	397.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,43S5U@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
SRR25158397_k127_3074727_3	234267.Acid_5032	2.333e-61	218.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_5032|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3074727_2	234267.Acid_5033	1.959e-64	238.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158397_k127_3074727_0	903818.KI912268_gene1426	7.631e-84	284.0	COG1385@1|root,COG1385@2|Bacteria	2|Bacteria	J	rRNA (uridine-N3-)-methyltransferase activity	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158397_k127_3074727_4	870187.Thini_1125	1.534e-22	105.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR25158397_k127_3074727_1	1519464.HY22_13745	1.392e-76	268.0	COG0618@1|root,COG0618@2|Bacteria,1FEID@1090|Chlorobi	1090|Chlorobi	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3090380_4	204669.Acid345_2810	1.516e-37	146.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158397_k127_3090380_0	204669.Acid345_2811	1.379e-187	598.0	COG0362@1|root,COG0362@2|Bacteria,3Y990@57723|Acidobacteria,2JP1Q@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158397_k127_3090380_10	1121904.ARBP01000018_gene2643	6.603e-16	91.0	COG5295@1|root,COG5295@2|Bacteria,4PHWW@976|Bacteroidetes,47ST5@768503|Cytophagia	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3090380_11	1463841.JOIR01000026_gene291	2.565e-09	70.0	COG0726@1|root,COG0726@2|Bacteria,2H418@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3090380_9	1340493.JNIF01000004_gene486	5.272e-17	94.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Autotransporter,PATR,Peptidase_S8
SRR25158397_k127_3090380_1	1123368.AUIS01000044_gene15	9.208e-128	428.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158397_k127_3090380_7	1173026.Glo7428_0134	7.49e-25	110.0	2DMJE@1|root,32RYR@2|Bacteria,1G6SI@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SRR25158397_k127_3090380_8	443143.GM18_3775	1.573e-20	106.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
SRR25158397_k127_3090380_12	588581.Cpap_0722	2.615e-06	60.0	COG2373@1|root,COG3210@1|root,COG3897@1|root,COG2373@2|Bacteria,COG3210@2|Bacteria,COG3897@2|Bacteria,1TR9M@1239|Firmicutes,24BEI@186801|Clostridia	186801|Clostridia	U	S-layer domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SLH
SRR25158397_k127_3090380_5	1095769.CAHF01000022_gene153	5.44e-26	117.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,2VTF9@28216|Betaproteobacteria	28216|Betaproteobacteria	I	SNARE associated Golgi protein	yabI_1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LssY_C,PAP2,SNARE_assoc
SRR25158397_k127_3090380_6	502025.Hoch_4460	1.473e-25	123.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158397_k127_3090380_2	671143.DAMO_3054	4.786e-98	354.0	COG5621@1|root,COG5621@2|Bacteria,2NPFN@2323|unclassified Bacteria	2|Bacteria	S	Lipocalin-like domain	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158397_k127_3090380_3	1173025.GEI7407_1871	1.248e-42	166.0	COG2367@1|root,COG2367@2|Bacteria,1G1KE@1117|Cyanobacteria,1HAFG@1150|Oscillatoriales	1117|Cyanobacteria	V	PFAM beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158397_k127_3104813_0	373994.Riv7116_5585	2.962e-201	663.0	COG1529@1|root,COG1529@2|Bacteria,1G35M@1117|Cyanobacteria,1HJ9D@1161|Nostocales	1117|Cyanobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158397_k127_3104813_2	745776.DGo_CA0728	1.167e-111	370.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer4_20,Pyr_redox_2,Pyr_redox_3
SRR25158397_k127_3104813_3	1356852.N008_00980	1.367e-69	243.0	COG2080@1|root,COG2080@2|Bacteria,4NH1B@976|Bacteroidetes,47TAM@768503|Cytophagia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2
SRR25158397_k127_3104813_4	1444711.CCJF01000005_gene259	3.51e-63	228.0	COG0564@1|root,COG0564@2|Bacteria,2JG28@204428|Chlamydiae	204428|Chlamydiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158397_k127_3104813_1	1123261.AXDW01000007_gene2380	2.103e-125	424.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,1X4KZ@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158397_k127_3105000_4	324602.Caur_2455	1.92e-68	239.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158397_k127_3105000_2	378806.STAUR_8180	4.168e-101	342.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YWKJ@29|Myxococcales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158397_k127_3105000_10	1221522.B723_19225	6.864e-39	151.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1YTU4@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
SRR25158397_k127_3105000_1	215803.DB30_4295	1.023e-119	406.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YYY4@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158397_k127_3105000_3	1547437.LL06_21680	5.645e-70	261.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,43IIJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	MA20_01825	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158397_k127_3105000_8	1499967.BAYZ01000090_gene4936	4.854e-45	186.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158397_k127_3105000_11	641526.ADIWIN_3077	5.339e-11	74.0	2DMHT@1|root,32RN3@2|Bacteria,4NPZK@976|Bacteroidetes,1I2PC@117743|Flavobacteriia	976|Bacteroidetes	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SRR25158397_k127_3105000_5	204669.Acid345_1827	4.283e-64	237.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	ComFC	-	-	-	-	-	-	-	-	-	-	-	DZR,Pribosyltran,zinc_ribbon_2
SRR25158397_k127_3105000_7	479434.Sthe_1762	5.062e-51	207.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3105000_6	234267.Acid_4617	3.246e-53	199.0	COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
SRR25158397_k127_3105000_0	246197.MXAN_6190	2.978e-131	433.0	COG0591@1|root,COG0591@2|Bacteria,1R4VK@1224|Proteobacteria,42UZA@68525|delta/epsilon subdivisions,2WSQC@28221|Deltaproteobacteria,2YVTZ@29|Myxococcales	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158397_k127_3110869_4	861299.J421_5687	1.465e-20	100.0	COG2207@1|root,COG2207@2|Bacteria,1ZV4P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158397_k127_3110869_3	526225.Gobs_2286	1.366e-22	110.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158397_k127_3110869_0	1123242.JH636435_gene2634	1.934e-95	327.0	COG0656@1|root,COG0656@2|Bacteria,2IWVI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158397_k127_3110869_5	138119.DSY2690	6.56e-09	69.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,261TT@186807|Peptococcaceae	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
SRR25158397_k127_3110869_2	42256.RradSPS_0832	1.805e-69	262.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4CU00@84995|Rubrobacteria	84995|Rubrobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158397_k127_3110869_1	177437.HRM2_44710	1.611e-88	301.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3113128_2	215803.DB30_8136	6.316e-69	241.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2YVGU@29|Myxococcales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158397_k127_3113128_1	944480.ATUV01000002_gene291	1.469e-151	512.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2M6H6@213113|Desulfurellales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158397_k127_3113128_0	880073.Calab_3492	2.766e-177	569.0	COG0017@1|root,COG0017@2|Bacteria,2NNQM@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class II (D, K and N)	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158397_k127_3113221_5	204669.Acid345_1670	1.307e-08	60.0	COG1544@1|root,COG1544@2|Bacteria,3Y533@57723|Acidobacteria,2JJE9@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal subunit interface protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158397_k127_3113221_0	338963.Pcar_1938	2.662e-137	452.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158397_k127_3113221_1	880073.Calab_3124	1.186e-95	320.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158397_k127_3113221_4	1267535.KB906767_gene3817	2.139e-34	136.0	COG5611@1|root,COG5611@2|Bacteria	2|Bacteria	S	PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_3113221_2	1356854.N007_14960	1.727e-65	252.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,2799P@186823|Alicyclobacillaceae	91061|Bacilli	T	PAS fold	-	-	2.7.13.3	ko:K02491	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR25158397_k127_3113221_3	378806.STAUR_0492	3.438e-46	173.0	2E4AE@1|root,32Z64@2|Bacteria,1NE9W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3113221_6	670307.HYPDE_24533	1.617e-06	57.0	COG1934@1|root,COG5375@1|root,COG1934@2|Bacteria,COG5375@2|Bacteria,1Q8G1@1224|Proteobacteria,2VEP1@28211|Alphaproteobacteria,3N9AZ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
SRR25158397_k127_3115039_16	1394178.AWOO02000088_gene953	4.207e-08	64.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4EKJ9@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_3115039_13	1449350.OCH239_01025	2.483e-26	126.0	COG0438@1|root,COG0438@2|Bacteria,1PDV1@1224|Proteobacteria,2U5AE@28211|Alphaproteobacteria,4KNDC@93682|Roseivivax	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_3115039_14	368408.Tpen_1716	3.07e-16	93.0	COG0500@1|root,arCOG01401@2157|Archaea,2XR2B@28889|Crenarchaeota	28889|Crenarchaeota	Q	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158397_k127_3115039_7	1125863.JAFN01000001_gene3405	1.972e-73	268.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158397_k127_3115039_3	1313304.CALK_1714	6.055e-116	404.0	COG0505@1|root,COG0505@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383,iYO844.BSU15510	CPSase_sm_chain,GATase
SRR25158397_k127_3115039_19	749927.AMED_9128	8.593e-07	61.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria,4DZEW@85010|Pseudonocardiales	201174|Actinobacteria	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
SRR25158397_k127_3115039_1	1111479.AXAR01000003_gene1713	5.327e-206	655.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,277YF@186823|Alicyclobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158397_k127_3115039_5	867845.KI911784_gene1260	4.961e-82	293.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
SRR25158397_k127_3115039_10	903818.KI912268_gene1040	4.531e-55	216.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DUF4388,DnaJ
SRR25158397_k127_3115039_18	452637.Oter_1009	2.688e-07	63.0	COG0810@1|root,COG0810@2|Bacteria,46WU9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158397_k127_3115039_11	278963.ATWD01000001_gene2439	2.19e-47	192.0	COG2010@1|root,COG2010@2|Bacteria,3Y650@57723|Acidobacteria,2JKDC@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3,Paired_CXXCH_1
SRR25158397_k127_3115039_2	247490.KSU1_C0527	3.84e-173	568.0	COG2132@1|root,COG2132@2|Bacteria,2IX3N@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158397_k127_3115039_6	1210884.HG799462_gene9164	5.953e-78	283.0	COG1538@1|root,COG1538@2|Bacteria,2IZB2@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158397_k127_3115039_17	1166018.FAES_pFAES01105	1.122e-07	64.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47NGP@768503|Cytophagia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_3,HlyD_D23
SRR25158397_k127_3115039_12	1122138.AQUZ01000002_gene2075	7.799e-38	153.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3115039_0	1125863.JAFN01000001_gene1462	1.578e-306	956.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158397_k127_3115039_15	1163409.UUA_03563	4.144e-13	71.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158397_k127_3115039_8	246197.MXAN_3426	6.533e-63	221.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2X520@28221|Deltaproteobacteria,2Z004@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158397_k127_3115039_9	1267533.KB906733_gene3362	1.022e-60	231.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158397_k127_3115039_4	1408254.T458_11335	1.911e-82	287.0	COG1234@1|root,COG1234@2|Bacteria,1TXG9@1239|Firmicutes,4HKX2@91061|Bacilli,26SKX@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158397_k127_3120647_3	1005048.CFU_1368	1.338e-44	173.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1RB8D@1224|Proteobacteria,2W871@28216|Betaproteobacteria,477Z9@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158397_k127_3120647_0	1123073.KB899241_gene2874	2.686e-114	378.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1S5XF@1236|Gammaproteobacteria,1X4HJ@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_3120647_1	1123073.KB899241_gene2875	1.856e-103	359.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1SYRB@1236|Gammaproteobacteria,1XCSU@135614|Xanthomonadales	135614|Xanthomonadales	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158397_k127_3120647_2	1267533.KB906736_gene960	1.623e-49	184.0	2A52F@1|root,30N7U@2|Bacteria,3Y80I@57723|Acidobacteria,2JN1S@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3120647_5	1288298.rosmuc_00727	8.739e-34	133.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2U70U@28211|Alphaproteobacteria,46R21@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRR25158397_k127_3120647_6	927677.ALVU02000002_gene221	7.921e-29	126.0	2BVEQ@1|root,32QU9@2|Bacteria,1GEVA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3120647_4	927677.ALVU02000002_gene219	1.637e-40	162.0	2BAD5@1|root,323TK@2|Bacteria,1GAVG@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3120647_8	219305.MCAG_00258	0.0007951	50.0	COG0477@1|root,COG2814@2|Bacteria,2GK86@201174|Actinobacteria,4DBM1@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_3123098_5	1280954.HPO_12178	0.0001927	54.0	COG4319@1|root,COG4319@2|Bacteria,1RDBF@1224|Proteobacteria,2U7AM@28211|Alphaproteobacteria,43Y3X@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158397_k127_3123098_0	272123.Anacy_3669	4.444e-82	299.0	COG0438@1|root,COG0438@2|Bacteria,1G699@1117|Cyanobacteria,1HSFF@1161|Nostocales	1117|Cyanobacteria	M	SPTR Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158397_k127_3123098_1	1227739.Hsw_1589	4.797e-50	203.0	COG0382@1|root,COG0382@2|Bacteria,4NNGX@976|Bacteroidetes	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158397_k127_3123098_2	240016.ABIZ01000001_gene703	1.313e-38	158.0	COG0438@1|root,COG2124@1|root,COG0438@2|Bacteria,COG2124@2|Bacteria,46XKY@74201|Verrucomicrobia,2IW5R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158397_k127_3123098_3	1303518.CCALI_01581	7.439e-18	97.0	2A08G@1|root,33ENC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3123098_4	558173.CDOO_05660	1.321e-05	49.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,22JW4@1653|Corynebacteriaceae	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158397_k127_3129427_9	1380346.JNIH01000003_gene2037	0.0007427	42.0	COG3896@1|root,COG3896@2|Bacteria,2IFF0@201174|Actinobacteria	201174|Actinobacteria	V	chloramphenicol	cpt	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
SRR25158397_k127_3129427_4	1123508.JH636445_gene6636	1.714e-41	157.0	COG5478@1|root,COG5478@2|Bacteria,2J05Z@203682|Planctomycetes	203682|Planctomycetes	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRR25158397_k127_3129427_6	1095769.CAHF01000013_gene3178	4.871e-35	139.0	COG5470@1|root,COG5470@2|Bacteria,1N54U@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158397_k127_3129427_1	290397.Adeh_0985	3.967e-70	256.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158397_k127_3129427_5	1267535.KB906767_gene5467	3.232e-36	141.0	COG1403@1|root,COG1403@2|Bacteria,3Y500@57723|Acidobacteria	57723|Acidobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR25158397_k127_3129427_8	1410620.SHLA_54c000060	3.187e-21	104.0	COG2823@1|root,COG2823@2|Bacteria,1N1R4@1224|Proteobacteria,2UDII@28211|Alphaproteobacteria,4BDVK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158397_k127_3129427_0	497964.CfE428DRAFT_3231	1.464e-195	625.0	COG0296@1|root,COG0296@2|Bacteria,46SFM@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha amylase, catalytic domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158397_k127_3129427_3	290397.Adeh_0314	1.309e-64	240.0	COG0599@1|root,COG0599@2|Bacteria,1QTWT@1224|Proteobacteria,43CBT@68525|delta/epsilon subdivisions,2X7MK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ahpD	-	-	ko:K04756	-	-	-	-	ko00000	-	-	-	CMD
SRR25158397_k127_3129427_2	290397.Adeh_0313	1.874e-66	231.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WP90@28221|Deltaproteobacteria,2YVP3@29|Myxococcales	28221|Deltaproteobacteria	O	Alkyl hydroperoxide reductase	prx-1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158397_k127_3129427_7	903818.KI912268_gene3050	7.672e-27	120.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158397_k127_3136698_3	1229909.NSED_00215	2.789e-12	81.0	COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR25158397_k127_3136698_4	215803.DB30_0358	6.634e-11	76.0	COG0823@1|root,COG1520@1|root,COG3055@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Ig_3,PD40,PKD,Peptidase_S8
SRR25158397_k127_3136698_5	349521.HCH_04710	2.145e-06	55.0	2C8HS@1|root,3332Q@2|Bacteria,1NGJM@1224|Proteobacteria,1SICC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3136698_0	646529.Desaci_3735	3.544e-124	409.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,261AX@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158397_k127_3136698_2	525904.Tter_1497	2.713e-44	166.0	COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158397_k127_3136698_1	1295642.H839_12659	4.602e-102	344.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1WEUJ@129337|Geobacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158397_k127_315493_2	1121920.AUAU01000009_gene1869	9.925e-108	358.0	COG0549@1|root,COG0549@2|Bacteria,3Y7CP@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158397_k127_315493_13	497964.CfE428DRAFT_2157	8.312e-21	106.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
SRR25158397_k127_315493_4	945713.IALB_0353	6.609e-73	254.0	COG0101@1|root,COG0101@2|Bacteria	2|Bacteria	J	tRNA pseudouridine synthase activity	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158397_k127_315493_8	498761.HM1_0203	8.557e-43	175.0	COG0611@1|root,COG0611@2|Bacteria,1V0SM@1239|Firmicutes,24J04@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158397_k127_315493_16	452637.Oter_1726	1.016e-13	79.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158397_k127_315493_11	634956.Geoth_0173	1.546e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1WETT@129337|Geobacillus	91061|Bacilli	K	binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_315493_5	290397.Adeh_0651	5.663e-68	263.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
SRR25158397_k127_315493_6	1444309.JAQG01000008_gene1716	1.449e-51	192.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,26T36@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158397_k127_315493_7	580340.Tlie_1420	8.457e-44	162.0	COG0335@1|root,COG0335@2|Bacteria,3TB9G@508458|Synergistetes	508458|Synergistetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158397_k127_315493_3	44251.PDUR_16725	1.557e-75	262.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158397_k127_315493_12	633697.EubceDRAFT1_0454	1.744e-26	115.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,25X91@186806|Eubacteriaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158397_k127_315493_14	665942.HMPREF1022_00855	2.752e-20	92.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MCGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158397_k127_315493_15	944479.JQLX01000015_gene135	7.872e-19	89.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2M7EP@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158397_k127_315493_9	1121920.AUAU01000006_gene301	2.315e-36	144.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_315493_0	1449126.JQKL01000022_gene130	1.937e-143	481.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2684D@186813|unclassified Clostridiales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158397_k127_315493_1	756499.Desde_1902	3.472e-125	417.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158397_k127_315493_10	1121104.AQXH01000003_gene404	9.766e-34	141.0	COG0415@1|root,COG0415@2|Bacteria	2|Bacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158397_k127_3177122_0	1382359.JIAL01000001_gene135	3.521e-253	797.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
SRR25158397_k127_3177122_1	1267534.KB906754_gene3783	1.633e-144	465.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158397_k127_3177122_2	457570.Nther_1911	5.832e-05	56.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia	186801|Clostridia	KT	Sigma-54 interaction domain	-	-	-	ko:K03721,ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	CBS,HTH_8,PAS,PAS_9,Sigma54_activat
SRR25158397_k127_3180578_3	1196029.ALIM01000014_gene3123	0.0001125	55.0	COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus	91061|Bacilli	S	metal-dependent membrane protease	ypbD	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158397_k127_3180578_2	1121957.ATVL01000007_gene2357	5.393e-52	193.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
SRR25158397_k127_3180578_0	316274.Haur_4673	1.636e-260	819.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi,3752D@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158397_k127_3180578_1	1047013.AQSP01000108_gene2058	3.347e-138	464.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_3181443_0	502025.Hoch_4718	3.016e-106	350.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
SRR25158397_k127_3181443_13	47763.JNZA01000012_gene6394	0.0001262	54.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GKQH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
SRR25158397_k127_3181443_10	1121459.AQXE01000001_gene2686	1.539e-13	83.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions,2WJ5Z@28221|Deltaproteobacteria,2MBCF@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158397_k127_3181443_12	756272.Plabr_3597	1.544e-06	57.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_6,HTH_18,PAS_4
SRR25158397_k127_3181443_3	379066.GAU_2047	3.871e-75	261.0	COG0586@1|root,COG0586@2|Bacteria,1ZTJB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158397_k127_3181443_1	1396141.BATP01000021_gene139	2.349e-102	351.0	COG0644@1|root,COG0644@2|Bacteria,46TJ0@74201|Verrucomicrobia,2IV4G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158397_k127_3181443_5	497964.CfE428DRAFT_1495	2.943e-66	243.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158397_k127_3181443_2	497964.CfE428DRAFT_0942	2.775e-85	297.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158397_k127_3181443_8	1121920.AUAU01000008_gene1666	1.176e-20	94.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158397_k127_3181443_11	562743.JH976434_gene1397	1.044e-06	56.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158397_k127_3181443_4	243231.GSU0460	4.607e-73	261.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,43TSR@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF-1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_3181443_9	67352.JODS01000022_gene3710	1.169e-19	102.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	sppA	-	-	ko:K14667	-	-	-	-	ko00000,ko01000,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_3181443_6	243231.GSU0245	3.382e-30	136.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42TG8@68525|delta/epsilon subdivisions,2WQC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3182231_0	1122176.KB903554_gene4017	8.087e-252	805.0	COG4888@1|root,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
SRR25158397_k127_3182231_2	1300345.LF41_2496	2.355e-17	94.0	COG1729@1|root,COG1729@2|Bacteria,1QU1J@1224|Proteobacteria,1T1M5@1236|Gammaproteobacteria,1X64F@135614|Xanthomonadales	135614|Xanthomonadales	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3182231_1	886293.Sinac_1729	6.932e-70	256.0	COG0501@1|root,COG0501@2|Bacteria,2J0GY@203682|Planctomycetes	203682|Planctomycetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158397_k127_3185893_9	219305.MCAG_00524	2.523e-31	127.0	COG0463@1|root,COG0463@2|Bacteria,2GJ9C@201174|Actinobacteria	201174|Actinobacteria	M	Reversibly glycosylated polypeptide	-	-	-	-	-	-	-	-	-	-	-	-	RGP
SRR25158397_k127_3185893_7	671143.DAMO_0905	2.333e-41	169.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3185893_4	1496688.ER33_03635	4.89e-73	262.0	COG1216@1|root,COG1216@2|Bacteria,1GIVG@1117|Cyanobacteria,22THI@167375|Cyanobium	1117|Cyanobacteria	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158397_k127_3185893_14	94122.Shewana3_1306	4.735e-08	65.0	COG2227@1|root,COG2227@2|Bacteria,1RKH0@1224|Proteobacteria,1S4HG@1236|Gammaproteobacteria,2Q9N5@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_3185893_10	41431.PCC8801_1830	7.194e-28	130.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_3185893_3	314345.SPV1_07461	3.349e-76	282.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158397_k127_3185893_6	292564.Cyagr_1205	6.288e-56	216.0	COG1215@1|root,COG1215@2|Bacteria,1GMNJ@1117|Cyanobacteria,22TKP@167375|Cyanobium	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3185893_12	1038858.AXBA01000001_gene3281	1.332e-14	87.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158397_k127_3185893_2	99598.Cal7507_0370	1.932e-77	279.0	COG1215@1|root,COG1215@2|Bacteria,1GIFC@1117|Cyanobacteria,1HJVN@1161|Nostocales	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
SRR25158397_k127_3185893_8	234267.Acid_4789	4.059e-35	137.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria	57723|Acidobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158397_k127_3185893_0	234267.Acid_6747	2.371e-234	737.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158397_k127_3185893_5	391008.Smal_0118	3.793e-72	264.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RZA4@1236|Gammaproteobacteria,1X7KS@135614|Xanthomonadales	135614|Xanthomonadales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158397_k127_3185893_13	1198452.Jab_2c09660	1.017e-09	70.0	COG4219@1|root,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,2WCAD@28216|Betaproteobacteria,4777S@75682|Oxalobacteraceae	28216|Betaproteobacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158397_k127_3185893_11	278963.ATWD01000001_gene3255	6.805e-16	82.0	COG3682@1|root,COG3682@2|Bacteria,3Y51U@57723|Acidobacteria,2JJMK@204432|Acidobacteriia	204432|Acidobacteriia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158397_k127_3185893_1	401053.AciPR4_3595	1.884e-103	344.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_3186509_0	215803.DB30_5624	1.514e-207	653.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42PXH@68525|delta/epsilon subdivisions,2WKEX@28221|Deltaproteobacteria,2YTWX@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158397_k127_3186509_1	1121920.AUAU01000006_gene333	2.182e-74	276.0	COG2897@1|root,COG2897@2|Bacteria,3Y5QK@57723|Acidobacteria	57723|Acidobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_3186509_4	468059.AUHA01000004_gene2375	6.726e-17	91.0	2BXBG@1|root,33WQF@2|Bacteria,4P3CB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3186509_2	713586.KB900536_gene2460	6.161e-50	190.0	COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,1S2VU@1236|Gammaproteobacteria,1WYNS@135613|Chromatiales	135613|Chromatiales	J	pteridine-dependent deoxygenase	-	-	4.1.3.40,4.1.3.45	ko:K18240	ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110	M00117	R01302,R10597	RC00491,RC02148,RC03212	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158397_k127_3186509_3	1174528.JH992898_gene4370	4.979e-30	121.0	COG2929@1|root,COG2929@2|Bacteria,1GKP2@1117|Cyanobacteria,1JMH9@1189|Stigonemataceae	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
SRR25158397_k127_3186509_6	1173028.ANKO01000041_gene3194	1.071e-11	69.0	2C6B2@1|root,335GA@2|Bacteria,1G9BT@1117|Cyanobacteria,1HDYH@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3186509_5	3218.PP1S40_57V6.1	2.471e-14	77.0	COG0167@1|root,KOG1799@2759|Eukaryota,37JTE@33090|Viridiplantae,3GDIQ@35493|Streptophyta	35493|Streptophyta	F	dihydropyrimidine dehydrogenase	-	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016627,GO:0016628,GO:0016651,GO:0017113,GO:0017144,GO:0019860,GO:0031667,GO:0031668,GO:0031669,GO:0034641,GO:0042737,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0055086,GO:0055114,GO:0071496,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.3.1.2	ko:K00207	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00978,R01415,R08226	RC00072,RC00123,RC02245	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158397_k127_3188880_2	1121124.JNIX01000015_gene2040	1.673e-79	292.0	COG1629@1|root,COG4771@2|Bacteria,1PSM0@1224|Proteobacteria,2U3MX@28211|Alphaproteobacteria,2KHTG@204458|Caulobacterales	204458|Caulobacterales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158397_k127_3188880_1	1500890.JQNL01000001_gene1992	8.476e-90	307.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1X40N@135614|Xanthomonadales	135614|Xanthomonadales	K	LacI family	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158397_k127_3188880_0	330214.NIDE4312	3.033e-92	307.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158397_k127_3250361_1	493475.GARC_2930	2.046e-90	323.0	COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CIA30
SRR25158397_k127_3250361_3	1182590.BN5_03942	5.628e-31	128.0	COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S7Z5@1236|Gammaproteobacteria,1YJ27@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158397_k127_3250361_2	1125863.JAFN01000001_gene3407	1.909e-68	239.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158397_k127_3250361_0	1267533.KB906737_gene1987	6.118e-122	400.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158397_k127_3252001_0	215803.DB30_7179	2.884e-167	538.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,42YQP@68525|delta/epsilon subdivisions,2WTJM@28221|Deltaproteobacteria,2YY5X@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158397_k127_3252001_5	543632.JOJL01000050_gene7440	1.112e-19	100.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DAJ5@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_3252001_10	1163671.JAGI01000002_gene3000	0.0002778	52.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,36DPS@31979|Clostridiaceae	186801|Clostridia	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5,Response_reg
SRR25158397_k127_3252001_2	1267535.KB906767_gene4437	9.416e-81	284.0	COG3285@1|root,COG3285@2|Bacteria,3Y637@57723|Acidobacteria,2JM9H@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158397_k127_3252001_3	1144275.COCOR_05441	2.392e-68	253.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTWP@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158397_k127_3252001_1	448385.sce7823	2.346e-104	353.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42R0K@68525|delta/epsilon subdivisions,2WMTU@28221|Deltaproteobacteria,2Z309@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158397_k127_3252001_4	1267535.KB906767_gene784	3.082e-27	118.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_3252001_8	189753.AXAS01000029_gene6899	1.342e-09	68.0	COG1752@1|root,COG1752@2|Bacteria,1RBKJ@1224|Proteobacteria,2U5NH@28211|Alphaproteobacteria,3K5U9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158397_k127_3256444_1	452637.Oter_0623	2.533e-50	183.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158397_k127_3256444_2	1297742.A176_01071	1.841e-47	186.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158397_k127_3256444_0	1254432.SCE1572_35880	2.568e-208	660.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YUEB@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158397_k127_3256444_3	1120948.KB903217_gene1061	9.084e-11	73.0	2DSMY@1|root,33GQS@2|Bacteria,2GVW6@201174|Actinobacteria,4E7K8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
SRR25158397_k127_3258842_9	1340493.JNIF01000004_gene148	4.035e-33	132.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria	57723|Acidobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3258842_13	234267.Acid_0495	6.016e-05	52.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3258842_3	234267.Acid_0496	2.255e-71	258.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158397_k127_3258842_2	234267.Acid_0497	2.531e-110	366.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
SRR25158397_k127_3258842_0	234267.Acid_0498	3.588e-261	814.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158397_k127_3258842_4	204669.Acid345_2994	2.844e-63	224.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria,2JI50@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158397_k127_3258842_11	682795.AciX8_0186	2.955e-11	70.0	2DR0H@1|root,339NS@2|Bacteria,3Y59F@57723|Acidobacteria,2JJP9@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Caa(3)-type oxidase, subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158397_k127_3258842_12	1499967.BAYZ01000103_gene3780	1.359e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3780|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3258842_10	1121861.KB899948_gene2455	3.772e-13	77.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,2UDE1@28211|Alphaproteobacteria,2JY9R@204441|Rhodospirillales	204441|Rhodospirillales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_3258842_5	448385.sce5596	2.125e-54	204.0	2DMDJ@1|root,32UGS@2|Bacteria,1QA6S@1224|Proteobacteria,434V9@68525|delta/epsilon subdivisions,2WZ6E@28221|Deltaproteobacteria,2Z1F8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3258842_1	1300345.LF41_128	1.948e-233	756.0	COG1404@1|root,COG1409@1|root,COG2304@1|root,COG3979@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG2304@2|Bacteria,COG3979@2|Bacteria,1QXFK@1224|Proteobacteria,1SJFI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3258842_6	485918.Cpin_4520	2.364e-37	144.0	COG3631@1|root,COG3631@2|Bacteria,4NTMZ@976|Bacteroidetes,1IZ30@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158397_k127_3258842_7	365046.Rta_31700	1.347e-36	143.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,2VVCB@28216|Betaproteobacteria,4AF2Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
SRR25158397_k127_3258842_8	243090.RB6586	3.101e-34	140.0	COG5403@1|root,COG5403@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158397_k127_3259053_5	526225.Gobs_2509	3.729e-77	271.0	COG1633@1|root,COG1633@2|Bacteria,2I2TU@201174|Actinobacteria,4EWCY@85013|Frankiales	201174|Actinobacteria	S	Ferritin-like	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin-like
SRR25158397_k127_3259053_4	215803.DB30_0658	4.669e-120	420.0	2DBN3@1|root,2ZA1Q@2|Bacteria,1PXHC@1224|Proteobacteria,438NW@68525|delta/epsilon subdivisions,2X3WR@28221|Deltaproteobacteria,2YXD5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3259053_8	1340493.JNIF01000004_gene94	2.551e-63	234.0	COG1680@1|root,COG1680@2|Bacteria,3Y3WB@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_3259053_11	1031711.RSPO_c00286	4.866e-27	117.0	2DRTA@1|root,33CYI@2|Bacteria,1P82P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3259053_12	1150469.RSPPHO_03037	1.097e-21	100.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158397_k127_3259053_1	903818.KI912268_gene1769	1.104e-185	586.0	COG0798@1|root,COG0798@2|Bacteria,3Y431@57723|Acidobacteria	57723|Acidobacteria	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
SRR25158397_k127_3259053_10	215803.DB30_4022	2.274e-32	141.0	COG1309@1|root,COG1309@2|Bacteria,1N9ZB@1224|Proteobacteria,42VC2@68525|delta/epsilon subdivisions,2WRA9@28221|Deltaproteobacteria,2YWGI@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158397_k127_3259053_7	1382306.JNIM01000001_gene2592	4.055e-69	251.0	COG1028@1|root,COG1028@2|Bacteria,2G8S6@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158397_k127_3259053_2	1121430.JMLG01000007_gene2533	1.208e-162	528.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,260H6@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158397_k127_3259053_0	316274.Haur_4394	6.504e-238	757.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
SRR25158397_k127_3259053_9	1297742.A176_01943	2.97e-42	159.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,42UJU@68525|delta/epsilon subdivisions,2WQI6@28221|Deltaproteobacteria,2YYTJ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158397_k127_3259053_3	324602.Caur_3220	4.303e-154	496.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158397_k127_3259053_6	1120966.AUBU01000003_gene1575	4.073e-70	261.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,47Y2N@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158397_k127_3259053_14	1382356.JQMP01000001_gene1284	2.099e-07	59.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi,27ZAC@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158397_k127_3259053_13	886293.Sinac_1397	1.723e-10	72.0	COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3278570_11	326297.Sama_1471	9.446e-19	102.0	COG0845@1|root,COG0845@2|Bacteria,1RCT0@1224|Proteobacteria,1S3AD@1236|Gammaproteobacteria,2QABY@267890|Shewanellaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SRR25158397_k127_3278570_4	1449346.JQMO01000002_gene1379	1.092e-75	266.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,2M0F6@2063|Kitasatospora	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158397_k127_3278570_6	479433.Caci_2591	4.469e-38	151.0	COG0664@1|root,COG0664@2|Bacteria,2INMI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_3278570_3	1123501.KB902287_gene1974	3.075e-102	350.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158397_k127_3278570_1	555079.Toce_1476	4.506e-117	400.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,42FDT@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158397_k127_3278570_5	1122185.N792_05815	6.822e-42	169.0	2B2WH@1|root,31VH2@2|Bacteria,1QCMM@1224|Proteobacteria,1T8D0@1236|Gammaproteobacteria,1XAGE@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3278570_2	87626.PTD2_02771	4.781e-108	381.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,2PZMF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_3278570_8	640081.Dsui_0425	4.608e-33	130.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,2KX06@206389|Rhodocyclales	206389|Rhodocyclales	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158397_k127_3278570_12	1166018.FAES_3669	4.282e-17	89.0	2EBX7@1|root,335WI@2|Bacteria,4NV52@976|Bacteroidetes,47QDZ@768503|Cytophagia	976|Bacteroidetes	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
SRR25158397_k127_3278570_10	937777.Deipe_2469	1.065e-20	104.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158397_k127_3278570_7	443144.GM21_0734	1.285e-34	142.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria,43SGZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRR25158397_k127_3278570_9	1463917.JODC01000001_gene481	1.349e-21	103.0	COG2310@1|root,COG2340@1|root,COG2310@2|Bacteria,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria	201174|Actinobacteria	T	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
SRR25158397_k127_3278570_0	1242864.D187_007079	4.561e-206	664.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3297105_4	1173023.KE650771_gene1781	6.961e-177	564.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRR25158397_k127_3297105_20	40571.JOEA01000042_gene5862	1.544e-19	96.0	COG0398@1|root,COG0398@2|Bacteria,2GN68@201174|Actinobacteria,4E6V6@85010|Pseudonocardiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_3297105_24	1313172.YM304_07430	2.272e-08	67.0	COG3391@1|root,COG4447@1|root,COG3391@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K07004,ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,HYR,fn3
SRR25158397_k127_3297105_8	401053.AciPR4_3594	8.276e-101	353.0	COG0457@1|root,COG0457@2|Bacteria,3Y77J@57723|Acidobacteria,2JM29@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158397_k127_3297105_16	243231.GSU0245	3.617e-50	187.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42TG8@68525|delta/epsilon subdivisions,2WQC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3297105_0	65393.PCC7424_3966	2.791e-312	977.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,3KGBX@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158397_k127_3297105_15	1267534.KB906756_gene711	1.189e-51	194.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_3297105_5	1504981.KO116_0183	1.444e-166	543.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XIG3@135619|Oceanospirillales	135619|Oceanospirillales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158397_k127_3297105_14	483219.LILAB_29390	1.023e-59	231.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2X0CC@28221|Deltaproteobacteria,2Z0IE@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158397_k127_3297105_21	986075.CathTA2_1988	4.177e-18	89.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli	91061|Bacilli	S	acetoin utilization protein	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158397_k127_3297105_13	543728.Vapar_0689	1.076e-65	233.0	COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,2WH8H@28216|Betaproteobacteria,4ADUR@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158397_k127_3297105_1	322710.Avin_02480	1.606e-255	812.0	COG0392@1|root,COG0474@1|root,COG0392@2|Bacteria,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531,ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24,3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,LPG_synthase_TM
SRR25158397_k127_3297105_19	1380390.JIAT01000010_gene3914	3.445e-25	115.0	COG4635@1|root,COG4635@2|Bacteria,2INN9@201174|Actinobacteria,4CTGJ@84995|Rubrobacteria	84995|Rubrobacteria	CH	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
SRR25158397_k127_3297105_12	713586.KB900536_gene373	6.736e-73	269.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1REBC@1224|Proteobacteria	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158397_k127_3297105_17	204669.Acid345_3455	1.066e-30	141.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_3297105_18	28072.Nos7524_2343	1.621e-25	109.0	COG5502@1|root,COG5502@2|Bacteria	2|Bacteria	V	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158397_k127_3297105_3	1304877.KI519399_gene1990	2.297e-211	670.0	COG0459@1|root,COG0459@2|Bacteria,1PMNK@1224|Proteobacteria,2TTPT@28211|Alphaproteobacteria,3JXCP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158397_k127_3297105_10	1499967.BAYZ01000158_gene442	9.625e-80	287.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158397_k127_3297105_22	65393.PCC7424_4631	3.635e-15	83.0	COG1592@1|root,COG1592@2|Bacteria,1G5YD@1117|Cyanobacteria,3KJBD@43988|Cyanothece	1117|Cyanobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158397_k127_3297105_26	118173.KB235914_gene769	0.0003809	52.0	COG1572@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Calx-beta,Chlam_PMP,DUF1573,DUF4347,HemolysinCabind
SRR25158397_k127_3297105_6	1144275.COCOR_03198	2.543e-134	441.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158397_k127_3297105_7	589865.DaAHT2_0540	8.209e-107	366.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2WKBM@28221|Deltaproteobacteria,2MHN3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRR25158397_k127_3297105_9	639030.JHVA01000001_gene3030	6.476e-87	300.0	COG0845@1|root,COG0845@2|Bacteria,3Y6R5@57723|Acidobacteria,2JKHW@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	-
SRR25158397_k127_3297105_2	489825.LYNGBM3L_63180	6.791e-216	706.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,1H9BF@1150|Oscillatoriales	1117|Cyanobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_3297105_11	706437.HMPREF0813_01263	3.989e-73	254.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,42D91@671232|Streptococcus anginosus group	91061|Bacilli	V	ABC transporter	XK27_06785	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_3302133_10	861299.J421_5914	1.691e-07	62.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
SRR25158397_k127_3302133_4	483219.LILAB_24070	2.688e-48	182.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107	-	-	ABC_tran
SRR25158397_k127_3302133_3	246197.MXAN_3257	1.361e-56	208.0	COG2386@1|root,COG2386@2|Bacteria,1QF23@1224|Proteobacteria,42RAM@68525|delta/epsilon subdivisions,2WMS1@28221|Deltaproteobacteria,2YVDV@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158397_k127_3302133_2	378806.STAUR_3693	7.704e-63	235.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2YVGN@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158397_k127_3302133_8	1144275.COCOR_02998	2.717e-32	131.0	COG2332@1|root,COG2332@2|Bacteria,1PZFU@1224|Proteobacteria,42U7H@68525|delta/epsilon subdivisions,2WQ19@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158397_k127_3302133_0	246197.MXAN_3253	2.818e-194	626.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158397_k127_3302133_5	215803.DB30_1964	8.097e-47	174.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVYE@29|Myxococcales	28221|Deltaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158397_k127_3302133_9	215803.DB30_1962	2.848e-21	105.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,43DRS@68525|delta/epsilon subdivisions,2X8U4@28221|Deltaproteobacteria,2Z0DW@29|Myxococcales	28221|Deltaproteobacteria	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158397_k127_3302133_11	1242864.D187_009981	1.875e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_009981|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3302133_12	1131269.AQVV01000022_gene2246	5.055e-05	55.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02198,ko:K02200	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmH,TPR_19,TPR_2
SRR25158397_k127_3302133_1	1379270.AUXF01000002_gene1723	4.034e-125	428.0	COG4772@1|root,COG4772@2|Bacteria,1ZSWK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_3302133_6	861299.J421_0752	1.58e-40	173.0	COG3201@1|root,COG3201@2|Bacteria,1ZTRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Nicotinamide mononucleotide transporter	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
SRR25158397_k127_3302133_7	861299.J421_0953	6.003e-34	142.0	COG3172@1|root,COG3172@2|Bacteria,1ZU4R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR25158397_k127_3311934_0	278963.ATWD01000001_gene2967	4.361e-32	145.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,3Y49I@57723|Acidobacteria,2JI4I@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,VCBS
SRR25158397_k127_3311934_2	319225.Plut_0703	6.76e-19	96.0	2C8AD@1|root,32RKP@2|Bacteria	2|Bacteria	S	Gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158397_k127_3311934_3	1121422.AUMW01000016_gene2089	2.269e-11	66.0	2DJCY@1|root,305NK@2|Bacteria,1TYFT@1239|Firmicutes,256D7@186801|Clostridia,266HZ@186807|Peptococcaceae	186801|Clostridia	S	Gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158397_k127_3311934_1	370438.PTH_0425	2.92e-25	109.0	arCOG06390@1|root,330IR@2|Bacteria,1VCE0@1239|Firmicutes,25D9K@186801|Clostridia,2636K@186807|Peptococcaceae	186801|Clostridia	S	Gas vesicle protein K	-	-	-	-	-	-	-	-	-	-	-	-	GvpK
SRR25158397_k127_3311934_4	861299.J421_0937	1.122e-07	54.0	2E5BC@1|root,3303G@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158397_k127_3347249_6	745277.GRAQ_00862	9.506e-88	293.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,3FH06@34037|Rahnella	1236|Gammaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSDY_1059.SDY_2206,iSF_1195.SF2102,iSFxv_1172.SFxv_2338,iS_1188.S2225	NTP_transferase
SRR25158397_k127_3347249_1	289376.THEYE_A0469	2.583e-150	484.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158397_k127_3347249_3	326427.Cagg_1542	4.364e-126	413.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158397_k127_3347249_2	1000565.METUNv1_01335	4.603e-145	483.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,2KUD6@206389|Rhodocyclales	206389|Rhodocyclales	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158397_k127_3347249_0	1173027.Mic7113_5255	2.494e-223	722.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158397_k127_3347249_13	1121272.KB903249_gene2169	4.165e-13	83.0	COG2373@1|root,COG2374@1|root,COG3250@1|root,COG5492@1|root,COG2373@2|Bacteria,COG2374@2|Bacteria,COG3250@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria,4DF33@85008|Micromonosporales	201174|Actinobacteria	E	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
SRR25158397_k127_3347249_14	1313172.YM304_10440	5.086e-12	79.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158397_k127_3347249_11	713587.THITH_09765	5.24e-25	122.0	COG3055@1|root,COG5640@1|root,COG3055@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,PPC,Trypsin
SRR25158397_k127_3347249_15	1121946.AUAX01000003_gene1729	5.377e-12	79.0	COG0726@1|root,COG0726@2|Bacteria,2GNF1@201174|Actinobacteria,4DBWD@85008|Micromonosporales	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3347249_12	1120950.KB892779_gene892	1.146e-18	91.0	COG3209@1|root,COG5184@1|root,COG3209@2|Bacteria,COG5184@2|Bacteria,2I35N@201174|Actinobacteria	201174|Actinobacteria	M	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
SRR25158397_k127_3347249_16	1384056.N787_08915	1.946e-10	74.0	COG2227@1|root,COG2227@2|Bacteria,1N6SE@1224|Proteobacteria,1SCC1@1236|Gammaproteobacteria,1X6AF@135614|Xanthomonadales	135614|Xanthomonadales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_3347249_8	357808.RoseRS_4085	2.102e-69	270.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3347249_10	1049564.TevJSym_at00330	2.832e-49	198.0	COG4627@1|root,COG4627@2|Bacteria,1N59B@1224|Proteobacteria	1224|Proteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_3347249_7	1134912.AJTV01000007_gene1036	2.092e-70	249.0	2AUD4@1|root,31K11@2|Bacteria,1RI0U@1224|Proteobacteria,2U998@28211|Alphaproteobacteria,36YHR@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158397_k127_3347249_9	316274.Haur_3711	3.057e-56	223.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158397_k127_3347249_5	472759.Nhal_0702	4.708e-94	344.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1S0D6@1236|Gammaproteobacteria,1WY3U@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
SRR25158397_k127_3347249_4	439235.Dalk_0708	3.056e-117	400.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR25158397_k127_3353963_4	1123508.JH636456_gene135	3.853e-45	170.0	COG2197@1|root,COG2197@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_3353963_5	1173027.Mic7113_3583	2.321e-42	162.0	COG2201@1|root,COG2201@2|Bacteria,1G50Z@1117|Cyanobacteria,1HBNC@1150|Oscillatoriales	1117|Cyanobacteria	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
SRR25158397_k127_3353963_8	648885.KB316284_gene4669	1.345e-06	63.0	2A4H1@1|root,30T3A@2|Bacteria,1PAYD@1224|Proteobacteria,2UXJJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3353963_0	1166018.FAES_3194	3.969e-270	874.0	COG0642@1|root,COG0840@1|root,COG1352@1|root,COG2201@1|root,COG2203@1|root,COG0642@2|Bacteria,COG0840@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2203@2|Bacteria,4PKNJ@976|Bacteroidetes,47JHY@768503|Cytophagia	976|Bacteroidetes	NT	protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158397_k127_3353963_2	861299.J421_0834	8.107e-92	307.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	MA20_24580	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158397_k127_3353963_1	1278073.MYSTI_02808	1.706e-115	383.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SRR25158397_k127_3353963_6	1123405.AUMM01000034_gene1692	1.896e-33	143.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
SRR25158397_k127_3353963_7	1340493.JNIF01000003_gene2471	6.735e-11	67.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3353963_3	290397.Adeh_1631	1.19e-84	293.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YURZ@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158397_k127_335727_2	1223545.GS4_08_00030	9.538e-48	172.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4GCHV@85026|Gordoniaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaC	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158397_k127_335727_4	1343739.PAP_08620	3.004e-22	105.0	COG0500@1|root,arCOG01791@2157|Archaea,2XW4Y@28890|Euryarchaeota	28890|Euryarchaeota	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158397_k127_335727_5	1229909.NSED_04975	2.394e-13	85.0	COG1361@1|root,arCOG04500@1|root,arCOG02079@2157|Archaea,arCOG04500@2157|Archaea	2157|Archaea	O	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CARDB,NosD,S_layer_C
SRR25158397_k127_335727_3	525897.Dbac_2072	5.243e-45	171.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,42TNH@68525|delta/epsilon subdivisions,2WQ32@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
SRR25158397_k127_335727_0	234267.Acid_4393	2.095e-149	502.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_335727_1	879309.HMPREF9199_0527	2.078e-70	272.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158397_k127_3368775_2	1356852.N008_05345	7.499e-97	324.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_3368775_3	1340493.JNIF01000003_gene1390	9.099e-89	306.0	COG2010@1|root,COG2010@2|Bacteria,3Y5ZT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158397_k127_3368775_6	913325.N799_12155	8.205e-44	171.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1X6DF@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158397_k127_3368775_5	1284708.HMPREF1634_05200	3.208e-48	194.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WCRJ@538999|Clostridiales incertae sedis	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158397_k127_3368775_4	224911.27355463	9.107e-88	299.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,3JRAH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158397_k127_3368775_7	316274.Haur_1002	4.614e-36	153.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi,375MG@32061|Chloroflexia	200795|Chloroflexi	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158397_k127_3368775_1	502025.Hoch_1577	3.418e-187	617.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_3368775_0	340099.Teth39_1468	4.432e-225	719.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,42EYB@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein synthesis factor, GTP-binding	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
SRR25158397_k127_3370198_10	861299.J421_5904	7.972e-36	154.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158397_k127_3370198_8	404589.Anae109_2915	1.322e-49	184.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3370198_2	1499967.BAYZ01000145_gene6209	7.668e-106	351.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158397_k127_3370198_13	1317122.ATO12_12685	1.432e-13	84.0	COG2730@1|root,COG3250@1|root,COG4733@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,COG4733@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2YJTE@290174|Aquimarina	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,F5_F8_type_C,fn3
SRR25158397_k127_3370198_9	1168289.AJKI01000036_gene3398	5.443e-45	185.0	COG3401@1|root,COG3534@1|root,COG4733@1|root,COG3401@2|Bacteria,COG3534@2|Bacteria,COG4733@2|Bacteria,4PJ0Q@976|Bacteroidetes,2G1H7@200643|Bacteroidia,3XKV2@558415|Marinilabiliaceae	976|Bacteroidetes	G	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6
SRR25158397_k127_3370198_6	935567.JAES01000020_gene574	1.624e-61	219.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1X6M5@135614|Xanthomonadales	135614|Xanthomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158397_k127_3370198_11	391625.PPSIR1_24309	1.407e-29	132.0	COG0142@1|root,COG0142@2|Bacteria	2|Bacteria	H	isoprenoid biosynthetic process	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158397_k127_3370198_1	1454004.AW11_00278	1.331e-164	552.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VZID@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
SRR25158397_k127_3370198_5	1382359.JIAL01000001_gene1856	4.56e-66	233.0	2E2IR@1|root,32XNB@2|Bacteria	2|Bacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
SRR25158397_k127_3370198_7	880073.Calab_3797	8.009e-52	207.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,HisKA_3,PAS_9,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
SRR25158397_k127_3370198_18	264462.Bd2202	2.134e-05	51.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SRR25158397_k127_3370198_14	1121920.AUAU01000002_gene2020	3.17e-10	64.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	spxA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1,1.97.1.4,3.2.2.24	ko:K00537,ko:K04069,ko:K05521,ko:K16509	-	-	R04710	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SRR25158397_k127_3370198_3	1242864.D187_000900	7.373e-98	332.0	COG0526@1|root,COG0526@2|Bacteria,1NH1D@1224|Proteobacteria,42XJ2@68525|delta/epsilon subdivisions,2X5GC@28221|Deltaproteobacteria,2YUZX@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
SRR25158397_k127_3370198_17	483219.LILAB_12015	6.764e-06	51.0	COG0526@1|root,COG0526@2|Bacteria,1NH1D@1224|Proteobacteria,42XJ2@68525|delta/epsilon subdivisions,2X5GC@28221|Deltaproteobacteria,2YUZX@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
SRR25158397_k127_3370198_0	929556.Solca_2421	4.66e-242	766.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158397_k127_3370198_4	118163.Ple7327_0853	1.065e-82	282.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,3VJ43@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158397_k127_3375341_1	1123392.AQWL01000002_gene1743	7.203e-64	233.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1KSXA@119069|Hydrogenophilales	119069|Hydrogenophilales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3375341_3	498848.TaqDRAFT_5234	3.767e-44	183.0	COG1361@1|root,COG3420@1|root,COG1361@2|Bacteria,COG3420@2|Bacteria,1WNFU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11
SRR25158397_k127_3375341_6	1278073.MYSTI_04209	1.022e-07	62.0	COG2932@1|root,COG2932@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158397_k127_3375341_4	335543.Sfum_2373	1.52e-28	127.0	COG1117@1|root,COG1117@2|Bacteria,1NMB4@1224|Proteobacteria,42XIZ@68525|delta/epsilon subdivisions,2WTEA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3375341_0	335543.Sfum_2372	3.863e-83	291.0	COG0535@1|root,COG0535@2|Bacteria,1MYFX@1224|Proteobacteria,42SB0@68525|delta/epsilon subdivisions,2WPF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158397_k127_3375341_7	985665.HPL003_26400	3.951e-07	59.0	2DJVE@1|root,307G4@2|Bacteria,1U1MD@1239|Firmicutes,4IB3T@91061|Bacilli,273NG@186822|Paenibacillaceae	91061|Bacilli	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158397_k127_3375341_2	1047013.AQSP01000061_gene1215	4.045e-55	202.0	COG1028@1|root,COG1028@2|Bacteria,2NRAR@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158397_k127_3375341_5	1408433.JHXV01000001_gene774	6.226e-16	83.0	COG0745@1|root,COG0745@2|Bacteria,4NP5C@976|Bacteroidetes,1I24M@117743|Flavobacteriia,2PBYT@246874|Cryomorphaceae	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_3384088_4	317619.ANKN01000146_gene3868	7.119e-57	207.0	COG5424@1|root,COG5424@2|Bacteria,1G23M@1117|Cyanobacteria	1117|Cyanobacteria	H	Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158397_k127_3384088_3	1123360.thalar_00122	1.802e-60	229.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2TSDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158397_k127_3384088_6	1123508.JH636442_gene3989	5.483e-25	120.0	COG1366@1|root,COG2202@1|root,COG3920@1|root,COG1366@2|Bacteria,COG2202@2|Bacteria,COG3920@2|Bacteria,2J004@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_4
SRR25158397_k127_3384088_2	404589.Anae109_2915	1.807e-66	233.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3384088_1	425104.Ssed_3637	1.043e-96	338.0	COG3591@1|root,COG3591@2|Bacteria,1RFR4@1224|Proteobacteria	1224|Proteobacteria	EO	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
SRR25158397_k127_3384088_7	1267535.KB906767_gene688	4.617e-06	58.0	2EVWN@1|root,33PAB@2|Bacteria,3Y5UR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3384088_5	234267.Acid_2646	5.449e-44	185.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3384088_0	234267.Acid_2647	8.98e-282	900.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_3398945_4	391038.Bphy_3085	5.386e-08	62.0	299P3@1|root,2ZWRE@2|Bacteria,1P569@1224|Proteobacteria,2W5QU@28216|Betaproteobacteria,1K1I6@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3398945_2	640511.BC1002_4341	6.15e-54	211.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,1K5RP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
SRR25158397_k127_3398945_1	398767.Glov_3242	9.511e-59	229.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2X5NU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
SRR25158397_k127_3398945_3	1089552.KI911559_gene1177	1.093e-13	85.0	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,2UJ6U@28211|Alphaproteobacteria,2JUF5@204441|Rhodospirillales	204441|Rhodospirillales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
SRR25158397_k127_3398945_0	247634.GPB2148_1949	5.17e-175	561.0	COG1032@1|root,COG1032@2|Bacteria,1RECP@1224|Proteobacteria,1SPEE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158397_k127_3401245_3	1408322.JHYK01000001_gene1583	7.559e-13	69.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,27I71@186928|unclassified Lachnospiraceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158397_k127_3401245_2	1200792.AKYF01000027_gene331	3.515e-62	221.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,26S4F@186822|Paenibacillaceae	91061|Bacilli	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
SRR25158397_k127_3401245_1	448385.sce6161	2.224e-63	222.0	COG4636@1|root,COG4636@2|Bacteria,1RCFH@1224|Proteobacteria,437EF@68525|delta/epsilon subdivisions,2X2KT@28221|Deltaproteobacteria,2Z042@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_3401245_0	234267.Acid_5235	9.612e-121	402.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158397_k127_3401245_4	317936.Nos7107_4296	8.491e-07	61.0	COG1524@1|root,COG1524@2|Bacteria,1G4AF@1117|Cyanobacteria	1117|Cyanobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158397_k127_3426058_2	1173027.Mic7113_2544	7.43e-81	300.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Ribonuclease BN-like family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158397_k127_3426058_0	234267.Acid_3623	1.989e-197	634.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158397_k127_3426058_1	111780.Sta7437_1635	1.514e-97	326.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,3VIAS@52604|Pleurocapsales	1117|Cyanobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158397_k127_3426058_3	349124.Hhal_1333	1.294e-30	124.0	COG0840@1|root,COG0840@2|Bacteria,1RKC0@1224|Proteobacteria,1SD9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	photoactive yellow protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS
SRR25158397_k127_3431886_2	1278073.MYSTI_05965	2.382e-48	194.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_3431886_5	715226.ABI_28870	3.444e-28	127.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2KI46@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_3431886_3	234267.Acid_2196	1.309e-45	179.0	COG2972@1|root,COG2972@2|Bacteria,3Y4IB@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_3431886_0	471223.GWCH70_0033	3.114e-173	571.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1WEZ0@129337|Geobacillus	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158397_k127_3431886_6	1121468.AUBR01000025_gene2973	3.444e-26	116.0	COG1215@1|root,COG1215@2|Bacteria,1UK60@1239|Firmicutes,24IGY@186801|Clostridia,42J7I@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3431886_4	404380.Gbem_1607	1.49e-37	152.0	COG0500@1|root,COG2226@2|Bacteria,1NGGF@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_3431886_7	1089545.KB913037_gene3952	5.176e-05	57.0	COG1680@1|root,COG1680@2|Bacteria,2GJQG@201174|Actinobacteria,4DYEI@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Peptidase_M6
SRR25158397_k127_3431886_1	472759.Nhal_1340	1.79e-154	509.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,1RZ9B@1236|Gammaproteobacteria,1WXG4@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3444996_3	1056816.JAFQ01000004_gene4449	6.795e-31	128.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,4FWIG@85025|Nocardiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158397_k127_3444996_2	1382359.JIAL01000001_gene1783	5.145e-88	303.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158397_k127_3444996_0	1128421.JAGA01000001_gene2075	1.077e-126	432.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-3	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158397_k127_3444996_6	1120959.ATXF01000005_gene1021	0.0001894	49.0	COG1848@1|root,COG1848@2|Bacteria,2IIF6@201174|Actinobacteria,4FSTD@85023|Microbacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_3444996_5	419947.MRA_2623A	1.514e-07	56.0	COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3444996_1	1123278.KB893500_gene216	1.702e-110	366.0	COG1506@1|root,COG1506@2|Bacteria,4NH1V@976|Bacteroidetes,47TY4@768503|Cytophagia	976|Bacteroidetes	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158397_k127_3444996_4	1173020.Cha6605_3883	1.917e-24	118.0	2E6NS@1|root,33197@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_344577_2	247490.KSU1_D0506	1.38e-48	188.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158397_k127_344577_0	247490.KSU1_D0507	0.0	1880.0	COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_344577_3	208439.AJAP_12790	9.443e-32	133.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EAE7@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	senR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_344577_4	1297742.A176_00476	3.865e-05	56.0	COG0845@1|root,COG0845@2|Bacteria,1Q2C6@1224|Proteobacteria,437YK@68525|delta/epsilon subdivisions,2X38G@28221|Deltaproteobacteria,2YUTX@29|Myxococcales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158397_k127_344577_1	1242864.D187_000431	6.863e-97	329.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJEY@28221|Deltaproteobacteria,2YUDX@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158397_k127_3453728_1	335543.Sfum_2358	1.016e-29	138.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	2.4.1.52	ko:K00712	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	DUF285,Glycos_transf_1,MORN_2
SRR25158397_k127_3453728_0	865937.Gilli_1969	2.702e-34	153.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
SRR25158397_k127_3453728_2	502025.Hoch_1506	1.183e-07	66.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	pknD	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08282,ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NHL,Pkinase
SRR25158397_k127_348400_5	661367.LLO_1892	1.44e-17	98.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
SRR25158397_k127_348400_1	1123401.JHYQ01000021_gene1060	9.365e-66	256.0	COG1520@1|root,COG1520@2|Bacteria,1R4I1@1224|Proteobacteria,1SJ0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_348400_4	1123508.JH636445_gene6823	9.233e-36	146.0	COG0546@1|root,COG0546@2|Bacteria,2J0GC@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158397_k127_348400_3	697282.Mettu_3553	8.091e-45	179.0	COG0560@1|root,COG0560@2|Bacteria,1PIND@1224|Proteobacteria,1S9GK@1236|Gammaproteobacteria,1XEK5@135618|Methylococcales	135618|Methylococcales	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
SRR25158397_k127_348400_0	457396.CSBG_03387	1.226e-81	284.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,36E72@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158397_k127_348400_6	204669.Acid345_3597	1.928e-11	71.0	COG4319@1|root,COG4319@2|Bacteria,3Y89C@57723|Acidobacteria,2JNBD@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158397_k127_348400_2	639282.DEFDS_0857	2.552e-58	211.0	COG0111@1|root,COG0111@2|Bacteria,2GEPM@200930|Deferribacteres	200930|Deferribacteres	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158397_k127_3485653_0	483219.LILAB_01800	4.788e-93	313.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2YUNF@29|Myxococcales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SRR25158397_k127_3485653_3	1132441.KI519455_gene3261	8.629e-06	56.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,1W8EC@1268|Micrococcaceae	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158397_k127_3485653_1	1384056.N787_01780	8.711e-61	217.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3485653_2	661478.OP10G_3900	3.822e-18	86.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158397_k127_3499471_0	1089548.KI783301_gene2844	2.962e-121	407.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3WE8H@539002|Bacillales incertae sedis	91061|Bacilli	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158397_k127_3499471_5	234267.Acid_5252	1.856e-06	54.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
SRR25158397_k127_3499471_3	1128421.JAGA01000003_gene3091	2.494e-31	141.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_3499471_1	314285.KT71_04350	1.412e-71	259.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158397_k127_3499471_2	1408473.JHXO01000006_gene1084	5.877e-56	202.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158397_k127_3499471_4	453591.Igni_0859	6.187e-23	100.0	COG1167@1|root,arCOG00492@2157|Archaea,2XPUJ@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM Aminotransferase class I and II	agt	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158397_k127_3504180_3	378806.STAUR_0339	2.39e-25	111.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,43850@68525|delta/epsilon subdivisions,2WX9Z@28221|Deltaproteobacteria,2YWVT@29|Myxococcales	28221|Deltaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158397_k127_3504180_1	479434.Sthe_1434	1.002e-41	165.0	COG1994@1|root,COG1994@2|Bacteria,2G8WG@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3504180_0	706587.Desti_3053	0.0	1022.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MQB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158397_k127_3504180_2	269799.Gmet_0479	1.088e-26	122.0	COG1669@1|root,COG1669@2|Bacteria,1NABR@1224|Proteobacteria,42WE0@68525|delta/epsilon subdivisions,2WRWK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_3504180_4	765912.Thimo_1989	1.254e-19	96.0	COG2361@1|root,COG2361@2|Bacteria,1N6ZA@1224|Proteobacteria,1S790@1236|Gammaproteobacteria,1WYSW@135613|Chromatiales	1224|Proteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158397_k127_3504180_5	1173027.Mic7113_5193	4.918e-11	65.0	COG1669@1|root,COG1669@2|Bacteria,1G6K9@1117|Cyanobacteria,1HCSN@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_3504180_6	502025.Hoch_4718	3.111e-08	57.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
SRR25158397_k127_3521085_3	270374.MELB17_03430	1.181e-20	95.0	COG3121@1|root,COG3121@2|Bacteria,1RFSJ@1224|Proteobacteria,1S3QQ@1236|Gammaproteobacteria,4681N@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG3121 P pilus assembly protein, chaperone PapD	-	-	-	-	-	-	-	-	-	-	-	-	PapD_N
SRR25158397_k127_3521085_0	270374.MELB17_03435	7.888e-160	540.0	COG3188@1|root,COG3266@1|root,COG3188@2|Bacteria,COG3266@2|Bacteria,1R6ZJ@1224|Proteobacteria,1RRW9@1236|Gammaproteobacteria,4674H@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
SRR25158397_k127_3521085_2	497964.CfE428DRAFT_4639	2.566e-47	188.0	COG3437@1|root,COG3829@1|root,COG4585@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,46Z7I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,Response_reg
SRR25158397_k127_3521085_1	56780.SYN_01953	2.687e-48	187.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_3521085_4	1217720.ALOX01000094_gene3875	1.732e-05	52.0	COG0784@1|root,COG0784@2|Bacteria,1QVFS@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_352311_6	585501.HMPREF6123_0186	1.997e-10	68.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,2PR7M@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
SRR25158397_k127_352311_4	521098.Aaci_2781	2.11e-26	112.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli	91061|Bacilli	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158397_k127_352311_1	243231.GSU0388	2.807e-57	205.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158397_k127_352311_3	309801.trd_1599	4.735e-48	188.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,27XFQ@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
SRR25158397_k127_352311_2	882.DVU_1083	3.749e-54	198.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_352311_0	1125863.JAFN01000001_gene2110	3.278e-70	244.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158397_k127_352311_5	903814.ELI_2724	1.62e-15	76.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,25UW4@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158397_k127_3533374_10	661478.OP10G_0237	0.0001735	54.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_3533374_8	886293.Sinac_1397	8.344e-16	92.0	COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3533374_6	1463900.JOIX01000035_gene3756	3.886e-22	106.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158397_k127_3533374_7	204669.Acid345_3996	5.708e-16	81.0	2CDNF@1|root,2ZTQP@2|Bacteria,3Y955@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3533374_5	523850.TON_1074	1.08e-43	168.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158397_k127_3533374_4	330214.NIDE0244	9.051e-87	291.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158397_k127_3533374_3	1125863.JAFN01000001_gene2317	8.163e-92	306.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SRR25158397_k127_3533374_1	1232443.BAIA02000149_gene1605	7.652e-123	413.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,268NG@186813|unclassified Clostridiales	186801|Clostridia	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158397_k127_3533374_9	760192.Halhy_1206	2.397e-06	56.0	2DMXT@1|root,32UAK@2|Bacteria,4NWD1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3533374_2	644283.Micau_2274	7.629e-113	384.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria,4DDHW@85008|Micromonosporales	201174|Actinobacteria	V	Ami_2	amiA1	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158397_k127_3533374_0	1382315.JPOI01000001_gene1962	6.766e-132	431.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1WE37@129337|Geobacillus	91061|Bacilli	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158397_k127_3564500_2	483219.LILAB_01425	3.927e-27	115.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
SRR25158397_k127_3564500_0	204669.Acid345_1454	3.881e-227	717.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158397_k127_3564500_1	234267.Acid_5065	1.298e-164	548.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria	57723|Acidobacteria	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158397_k127_3564500_3	722419.PH505_ao00670	0.0008002	42.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158397_k127_3565589_0	1341151.ASZU01000004_gene137	3.72e-50	200.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27BIU@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_3565589_2	1242864.D187_003866	0.000223	55.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
SRR25158397_k127_3565589_1	251221.35210716	1.159e-37	154.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRR25158397_k127_3571899_8	1215092.PA6_012_00330	0.000284	51.0	2DH1U@1|root,2ZY3B@2|Bacteria,1P4AC@1224|Proteobacteria,1STFQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3571899_5	84531.JMTZ01000010_gene3189	7.07e-32	131.0	COG4319@1|root,COG4319@2|Bacteria,1NH3X@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158397_k127_3571899_3	1294273.roselon_01976	2.494e-44	172.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158397_k127_3571899_0	1089550.ATTH01000001_gene363	5.744e-193	635.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1FJXK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_3571899_2	1216007.AOPM01000092_gene966	1.073e-73	257.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2Q1G4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158397_k127_3571899_6	278963.ATWD01000001_gene3360	2.072e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,3Y56E@57723|Acidobacteria,2JJQK@204432|Acidobacteriia	204432|Acidobacteriia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158397_k127_3571899_4	925409.KI911562_gene389	3.586e-37	148.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR25158397_k127_3571899_1	378806.STAUR_6538	2.795e-179	576.0	COG0304@1|root,COG0304@2|Bacteria,1Q3B2@1224|Proteobacteria,43927@68525|delta/epsilon subdivisions,2X47V@28221|Deltaproteobacteria,2YYFV@29|Myxococcales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_3573565_3	448385.sce0934	1.608e-103	344.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158397_k127_3573565_4	1116472.MGMO_172c00110	6.104e-58	222.0	COG3258@1|root,COG3258@2|Bacteria,1R95B@1224|Proteobacteria,1RYPN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3573565_2	1384054.N790_09790	2.501e-111	379.0	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,1X5X9@135614|Xanthomonadales	135614|Xanthomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158397_k127_3573565_7	204669.Acid345_2058	5.206e-19	102.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158397_k127_3573565_1	290397.Adeh_3048	1.09e-148	507.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria	1224|Proteobacteria	T	flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
SRR25158397_k127_3573565_6	404589.Anae109_2917	2.871e-22	102.0	COG3576@1|root,COG3576@2|Bacteria,1PT74@1224|Proteobacteria,432EH@68525|delta/epsilon subdivisions,2WXW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3573565_5	1192034.CAP_0501	1.751e-43	175.0	COG3386@1|root,COG3386@2|Bacteria,1QYGK@1224|Proteobacteria,437EJ@68525|delta/epsilon subdivisions,2X2KV@28221|Deltaproteobacteria,2Z04K@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3573565_0	1434929.X946_5109	5.488e-153	500.0	2DBCY@1|root,2Z8GH@2|Bacteria,1R3TQ@1224|Proteobacteria,2VXF6@28216|Betaproteobacteria,1KABG@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPO1_DWL,PPO1_KFDV,Tyrosinase
SRR25158397_k127_3573565_9	1434929.X946_5108	5.308e-10	65.0	COG5486@1|root,COG5486@2|Bacteria,1NCV8@1224|Proteobacteria,2VXQW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158397_k127_3574046_0	404589.Anae109_1724	0.0	1510.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158397_k127_3574046_3	278963.ATWD01000002_gene268	6.975e-62	223.0	COG0266@1|root,COG0266@2|Bacteria,3Y2WM@57723|Acidobacteria,2JIQF@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158397_k127_3574046_5	1121920.AUAU01000004_gene742	1.206e-55	198.0	COG3832@1|root,COG3832@2|Bacteria,3Y57B@57723|Acidobacteria	57723|Acidobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158397_k127_3574046_6	378806.STAUR_0350	1.646e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,4382M@68525|delta/epsilon subdivisions,2X3CP@28221|Deltaproteobacteria,2YVFV@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158397_k127_3574046_10	986075.CathTA2_2755	1.234e-09	68.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,4IR0X@91061|Bacilli	91061|Bacilli	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158397_k127_3574046_7	1166948.JPZL01000001_gene3111	1.891e-31	129.0	COG5592@1|root,COG5592@2|Bacteria,1ND3D@1224|Proteobacteria,1SPP8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hemerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158397_k127_3574046_2	861299.J421_2858	4.068e-85	295.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRR25158397_k127_3574046_9	1382359.JIAL01000001_gene564	3.033e-17	95.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158397_k127_3574046_1	204669.Acid345_3429	2.918e-112	379.0	COG1793@1|root,COG1793@2|Bacteria,3Y45N@57723|Acidobacteria,2JIH0@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158397_k127_3574046_4	234267.Acid_5076	2.324e-61	215.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158397_k127_3583311_1	220664.PFL_4314	3.435e-274	869.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1YPD6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158397_k127_3583311_0	1232410.KI421422_gene2032	7.267e-288	904.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158397_k127_3583311_6	316067.Geob_0003	1.708e-47	185.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,42SYJ@68525|delta/epsilon subdivisions,2WP80@28221|Deltaproteobacteria,43T4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158397_k127_3583311_4	234267.Acid_0002	2.297e-81	284.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria	57723|Acidobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158397_k127_3583311_2	1232410.KI421422_gene2035	6.592e-131	430.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,43RXU@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158397_k127_3583311_11	644966.Tmar_2374	1.364e-12	68.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158397_k127_3583311_10	643648.Slip_2384	3.949e-13	78.0	COG0594@1|root,COG0594@2|Bacteria,1UE92@1239|Firmicutes,25MZB@186801|Clostridia,42K8M@68298|Syntrophomonadaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158397_k127_3583311_8	1137268.AZXF01000017_gene2928	6.133e-26	113.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4EKGC@85012|Streptosporangiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158397_k127_3583311_5	1047013.AQSP01000133_gene2153	3.965e-77	281.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158397_k127_3583311_9	1262915.BN574_00164	1.458e-17	94.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4H41I@909932|Negativicutes	909932|Negativicutes	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158397_k127_3583311_3	1267534.KB906758_gene2239	1.908e-93	323.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158397_k127_3583311_7	1469613.JT55_01030	4.05e-43	160.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,3FCR9@34008|Rhodovulum	28211|Alphaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158397_k127_3590663_0	1313301.AUGC01000003_gene2172	1.39e-113	399.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158397_k127_3590663_1	105559.Nwat_0740	4.31e-73	258.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1WWM3@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158397_k127_3590663_3	204669.Acid345_2433	4.397e-39	150.0	COG4206@1|root,COG4206@2|Bacteria,3Y3IJ@57723|Acidobacteria,2JHQY@204432|Acidobacteriia	204432|Acidobacteriia	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_3590984_7	1131730.BAVI_22078	7.782e-14	82.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,1ZCSV@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_3590984_6	1169143.KB911039_gene4378	1.399e-18	92.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1K4TZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158397_k127_3590984_0	1128421.JAGA01000002_gene335	9.142e-153	495.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158397_k127_3590984_1	886293.Sinac_5331	6.079e-144	477.0	COG0249@1|root,COG0249@2|Bacteria,2IY9B@203682|Planctomycetes	203682|Planctomycetes	L	Mismatch repair ATPase (MutS family)	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
SRR25158397_k127_3590984_5	1283283.ATXA01000002_gene2661	7.398e-23	104.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4ESWE@85013|Frankiales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158397_k127_3590984_3	398767.Glov_3188	9.423e-79	282.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158397_k127_3590984_4	1121445.ATUZ01000011_gene223	2.016e-37	160.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2M7W9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158397_k127_3590984_2	204669.Acid345_0626	1.841e-99	336.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria,2JISH@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158397_k127_3634275_4	861299.J421_0953	1.037e-12	70.0	COG3172@1|root,COG3172@2|Bacteria,1ZU4R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR25158397_k127_3634275_1	1121439.dsat_1297	2.857e-37	154.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2M88U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3634275_3	1157708.KB907464_gene427	2.717e-14	86.0	COG1215@1|root,COG1215@2|Bacteria,1R4P3@1224|Proteobacteria,2W0RP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158397_k127_3634275_0	221359.RS9916_38442	2.733e-39	162.0	COG0438@1|root,COG0438@2|Bacteria,1GCNR@1117|Cyanobacteria,1GYNC@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158397_k127_3634275_2	525898.Sdel_2215	1.397e-18	100.0	COG4122@1|root,COG4122@2|Bacteria,1NA51@1224|Proteobacteria,42TE7@68525|delta/epsilon subdivisions,2YPKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158397_k127_3643128_6	639282.DEFDS_1109	2.219e-51	184.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158397_k127_3643128_0	204669.Acid345_1391	1.812e-180	570.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158397_k127_3643128_2	204669.Acid345_1390	1.357e-143	465.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158397_k127_3643128_5	1499967.BAYZ01000027_gene1787	5.212e-90	318.0	COG5000@1|root,COG5000@2|Bacteria,2NP6K@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158397_k127_3643128_3	1122918.KB907270_gene1567	9.088e-135	438.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,26RSM@186822|Paenibacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158397_k127_3643128_8	1389489.O159_01820	1.305e-05	58.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158397_k127_3643128_9	1389489.O159_01820	0.0005295	51.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158397_k127_3643128_1	941449.dsx2_0180	7.224e-172	557.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2M91Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158397_k127_3643128_4	671143.DAMO_2568	2.441e-108	357.0	COG1432@1|root,COG1432@2|Bacteria,2NQWI@2323|unclassified Bacteria	2|Bacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158397_k127_3643128_7	195522.BD01_2040	1.239e-21	108.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,242VX@183968|Thermococci	183968|Thermococci	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
SRR25158397_k127_3651965_2	68223.JNZY01000062_gene1108	8.151e-51	189.0	COG3848@1|root,COG3848@2|Bacteria,2IE61@201174|Actinobacteria	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
SRR25158397_k127_3651965_1	926560.KE387023_gene1920	2.608e-55	224.0	COG2374@1|root,COG2374@2|Bacteria,1WM95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SRR25158397_k127_3651965_0	755731.Clo1100_0574	2.377e-92	344.0	COG1864@1|root,COG2374@1|root,COG1864@2|Bacteria,COG2374@2|Bacteria	2|Bacteria	F	neuron death in response to oxidative stress	nucA	-	-	ko:K01173,ko:K07004	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS,Exo_endo_phos,LTD
SRR25158397_k127_3651965_3	1049564.TevJSym_bg00010	5.482e-23	117.0	COG1345@1|root,COG4932@1|root,COG1345@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,1T4AQ@1236|Gammaproteobacteria,1J7AR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cadherin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3651965_4	1123228.AUIH01000011_gene2035	1.346e-14	80.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1XINY@135619|Oceanospirillales	135619|Oceanospirillales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
SRR25158397_k127_3666450_4	398767.Glov_2209	1.149e-26	112.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42TG8@68525|delta/epsilon subdivisions,2WQC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3666450_0	204669.Acid345_2940	2.555e-177	571.0	COG2234@1|root,COG2234@2|Bacteria,3Y3SC@57723|Acidobacteria,2JIVJ@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158397_k127_3666450_6	1398491.P613_01810	1.347e-21	109.0	COG0455@1|root,COG0455@2|Bacteria,2J5K5@203691|Spirochaetes	203691|Spirochaetes	D	ATP-binding protein	ylxH-2	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
SRR25158397_k127_3666450_2	309799.DICTH_1701	1.131e-46	176.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_3666450_5	322710.Avin_36870	9.832e-25	110.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158397_k127_3666450_1	1121382.JQKG01000002_gene4555	4.521e-57	204.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	dedA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
SRR25158397_k127_3666450_3	234267.Acid_2025	8.252e-45	175.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158397_k127_3673321_5	1242864.D187_004338	1.357e-42	175.0	COG1520@1|root,COG2863@1|root,COG3055@1|root,COG4676@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,COG3055@2|Bacteria,COG4676@2|Bacteria,1N3U2@1224|Proteobacteria,43AYV@68525|delta/epsilon subdivisions,2X6D5@28221|Deltaproteobacteria,2YYUW@29|Myxococcales	2|Bacteria	C	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cytochrom_C,Cytochrome_CBB3,DUF5122,SBBP
SRR25158397_k127_3673321_1	1288494.EBAPG3_11750	6.08e-87	323.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE,KAP_NTPase,PG_binding_1,WD40
SRR25158397_k127_3673321_7	1123508.JH636448_gene7478	1.904e-10	65.0	2E7P7@1|root,3324T@2|Bacteria,2J1CK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158397_k127_3673321_0	1158318.ATXC01000002_gene1502	2.632e-90	304.0	COG0528@1|root,COG0528@2|Bacteria,2G4R5@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158397_k127_3673321_3	1391646.AVSU01000025_gene2438	5.566e-59	209.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,25QI8@186804|Peptostreptococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158397_k127_3673321_6	345219.Bcoa_1190	1.159e-36	153.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158397_k127_3673321_4	1160707.AJIK01000014_gene2682	2.081e-49	183.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,26EUH@186818|Planococcaceae	91061|Bacilli	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158397_k127_3673321_2	289376.THEYE_A2003	3.092e-77	274.0	COG0008@1|root,COG0008@2|Bacteria,3J0CJ@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158397_k127_3678567_0	290397.Adeh_3730	1.369e-139	455.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2YU2P@29|Myxococcales	28221|Deltaproteobacteria	C	ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158397_k127_3678567_3	1121468.AUBR01000005_gene40	1.931e-49	198.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_3678567_4	330214.NIDE4187	9.157e-43	167.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158397_k127_3678567_1	1142394.PSMK_08370	8.576e-88	306.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158397_k127_3678567_2	1198114.AciX9_0530	2.707e-50	192.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRR25158397_k127_3678567_5	518766.Rmar_0956	2.443e-05	47.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1FIV5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158397_k127_3698717_3	926549.KI421517_gene456	3.874e-55	199.0	arCOG09511@1|root,2Z9DH@2|Bacteria,4NIMU@976|Bacteroidetes,47N8K@768503|Cytophagia	976|Bacteroidetes	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
SRR25158397_k127_3698717_4	1201290.M902_2050	2.574e-46	184.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2MSXB@213481|Bdellovibrionales,2WNRU@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SRR25158397_k127_3698717_2	1242864.D187_004594	3.289e-60	217.0	28YTJ@1|root,2ZKKT@2|Bacteria,1RBH7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3698717_1	1500893.JQNB01000001_gene2798	3.842e-67	237.0	COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1T0AZ@1236|Gammaproteobacteria,1XCZV@135614|Xanthomonadales	135614|Xanthomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
SRR25158397_k127_3698717_7	391619.PGA1_c08500	0.0006995	49.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UF3D@28211|Alphaproteobacteria,34FSC@302485|Phaeobacter	28211|Alphaproteobacteria	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5
SRR25158397_k127_3698717_6	1121035.AUCH01000005_gene1	6.295e-07	55.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM peptidase M28	yfbL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158397_k127_3698717_0	1026882.MAMP_01710	5.643e-78	275.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,460F7@72273|Thiotrichales	72273|Thiotrichales	S	PQQ-dependent catabolism-associated beta-propeller protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
SRR25158397_k127_3698717_5	94624.Bpet3213	5.453e-21	95.0	COG2010@1|root,COG2010@2|Bacteria,1QVIB@1224|Proteobacteria,2W4Q7@28216|Betaproteobacteria,3T7TH@506|Alcaligenaceae	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158397_k127_3706548_5	722419.PH505_an00480	7.916e-42	166.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria,2PZK5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3706548_6	1242864.D187_005446	1.308e-28	133.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,42SCH@68525|delta/epsilon subdivisions,2WPMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158397_k127_3706548_4	1185876.BN8_00134	4.648e-61	225.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,47JA8@768503|Cytophagia	976|Bacteroidetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158397_k127_3706548_0	234267.Acid_0057	6.441e-130	436.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158397_k127_3706548_7	760117.JN27_18390	1.356e-16	89.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2WC8B@28216|Betaproteobacteria,4774U@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
SRR25158397_k127_3706548_1	379066.GAU_0512	1.147e-90	309.0	COG4299@1|root,COG4299@2|Bacteria,1ZT4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
SRR25158397_k127_3706548_2	404589.Anae109_0937	9.325e-69	242.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
SRR25158397_k127_3706548_3	404589.Anae109_0938	2.841e-61	219.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158397_k127_3710497_14	395019.Bmul_4593	1.292e-47	177.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2VHXE@28216|Betaproteobacteria,1K3TJ@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158397_k127_3710497_22	404589.Anae109_0016	1.161e-16	87.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3710497_24	227086.JGI_V11_18628	1.484e-05	57.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	SPY	GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377	-	ko:K10408	ko05016,map05016	-	-	-	ko00000,ko00001,ko04812	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_8
SRR25158397_k127_3710497_2	1382359.JIAL01000001_gene1153	2.817e-128	420.0	COG0436@1|root,COG0436@2|Bacteria,3Y64P@57723|Acidobacteria,2JMB5@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_3710497_15	335543.Sfum_3743	1.04e-45	181.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158397_k127_3710497_18	1305836.AXVE01000018_gene1268	3.147e-26	113.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,26F8W@186818|Planococcaceae	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158397_k127_3710497_21	931626.Awo_c16430	1.57e-18	95.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,25UTC@186806|Eubacteriaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158397_k127_3710497_9	290397.Adeh_1552	4.212e-63	220.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2YV1R@29|Myxococcales	28221|Deltaproteobacteria	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158397_k127_3710497_13	1499967.BAYZ01000028_gene1318	6.666e-48	184.0	COG0739@1|root,COG0739@2|Bacteria,2NPG3@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158397_k127_3710497_3	743719.PaelaDRAFT_5830	8.796e-110	370.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26QN5@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158397_k127_3710497_6	861299.J421_2109	2.919e-83	293.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158397_k127_3710497_0	1123508.JH636442_gene4220	1.81e-206	660.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158397_k127_3710497_1	379066.GAU_3087	3.262e-153	497.0	COG0076@1|root,COG0076@2|Bacteria,1ZSZN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158397_k127_3710497_4	247490.KSU1_A0059	1.101e-107	365.0	COG2148@1|root,COG2148@2|Bacteria,2IYWX@203682|Planctomycetes	203682|Planctomycetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158397_k127_3710497_5	1267535.KB906767_gene4670	5.498e-84	298.0	COG0438@1|root,COG0438@2|Bacteria,3Y6A8@57723|Acidobacteria	57723|Acidobacteria	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_trans_1_4
SRR25158397_k127_3710497_10	234267.Acid_7442	1.36e-62	239.0	COG1216@1|root,COG1216@2|Bacteria,3Y7CJ@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3710497_17	234267.Acid_7441	5.178e-39	162.0	COG1216@1|root,COG1216@2|Bacteria,3Y7JI@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158397_k127_3710497_16	40571.JOEA01000007_gene6513	8.506e-45	184.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRR25158397_k127_3710497_20	1193181.BN10_520057	1.139e-19	102.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4FHZD@85021|Intrasporangiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158397_k127_3710497_19	1382356.JQMP01000001_gene1008	2.413e-20	107.0	29X1J@1|root,30IPW@2|Bacteria,2GBCF@200795|Chloroflexi,27YRV@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3710497_8	639282.DEFDS_0214	5.799e-66	235.0	COG0253@1|root,COG0253@2|Bacteria,2GF22@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158397_k127_3710497_23	1198114.AciX9_0816	2.552e-16	93.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3710497_11	401526.TcarDRAFT_1028	1.932e-51	190.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4H2Z4@909932|Negativicutes	909932|Negativicutes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158397_k127_3710497_7	1121468.AUBR01000029_gene1582	1.555e-82	282.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158397_k127_3710497_12	1499967.BAYZ01000078_gene990	1.291e-50	192.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
SRR25158397_k127_3715469_2	335543.Sfum_0994	6.695e-45	171.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,2MQJQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158397_k127_3715469_0	1340493.JNIF01000003_gene1856	3.115e-150	489.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158397_k127_3715469_1	469382.Hbor_18170	2.075e-59	215.0	COG0434@1|root,arCOG01982@2157|Archaea,2XT9I@28890|Euryarchaeota,23T8W@183963|Halobacteria	183963|Halobacteria	S	photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
SRR25158397_k127_3744773_0	497964.CfE428DRAFT_1607	0.0	1283.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158397_k127_3744773_1	1121920.AUAU01000004_gene813	4.274e-81	286.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRR25158397_k127_376668_2	215803.DB30_6949	4.203e-101	358.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WN4R@28221|Deltaproteobacteria,2YVY4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158397_k127_376668_3	215803.DB30_6950	1.293e-80	284.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2X282@28221|Deltaproteobacteria,2YV1K@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158397_k127_376668_5	1121007.AUML01000015_gene3921	5.921e-05	54.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2YJJD@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
SRR25158397_k127_376668_0	1191523.MROS_1137	3.359e-178	605.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_376668_1	498761.HM1_2802	1.196e-169	549.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158397_k127_376668_4	1123060.JONP01000006_gene4835	1.216e-55	208.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria,2U8IJ@28211|Alphaproteobacteria,2JWHR@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158397_k127_3770390_6	105425.BBPL01000036_gene4350	1.667e-26	121.0	COG0500@1|root,COG2226@2|Bacteria,2IF5R@201174|Actinobacteria,2NHMA@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
SRR25158397_k127_3770390_1	234267.Acid_0690	9.197e-176	580.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158397_k127_3770390_3	404589.Anae109_1500	4.366e-71	246.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158397_k127_3770390_0	1519464.HY22_07105	1.247e-290	913.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158397_k127_3770390_2	396588.Tgr7_0102	1.301e-110	370.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158397_k127_3770390_4	1206777.B195_00475	6.523e-47	177.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1Z67H@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
SRR25158397_k127_3770390_5	1033743.CAES01000011_gene4458	1.48e-46	179.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,26T1M@186822|Paenibacillaceae	91061|Bacilli	S	Stress-induced protein	yloC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158397_k127_3770390_8	1110502.TMO_2832	1.279e-10	63.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,2JS37@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR25158397_k127_3772836_1	1242864.D187_002653	9.614e-75	263.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	darR	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158397_k127_3772836_4	1242864.D187_002652	9.997e-54	194.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM isochorismatase hydrolase	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158397_k127_3772836_7	1150398.JIBJ01000003_gene1626	3.583e-10	70.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_3772836_6	1245471.PCA10_47560	6.684e-38	145.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,1SA8S@1236|Gammaproteobacteria,1YGAY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158397_k127_3772836_0	861299.J421_3037	7.038e-227	711.0	COG1012@1|root,COG1012@2|Bacteria,1ZUF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_3772836_8	290512.Paes_0959	1.515e-08	67.0	COG2319@1|root,COG2319@2|Bacteria,1FFIC@1090|Chlorobi	1090|Chlorobi	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3772836_2	509190.Cseg_0176	1.014e-59	232.0	COG1752@1|root,COG1752@2|Bacteria,1RBKJ@1224|Proteobacteria,2U5NH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158397_k127_3772836_5	215803.DB30_2063	2.344e-46	172.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158397_k127_3772836_3	251221.35213336	4.458e-56	200.0	COG1718@1|root,COG1718@2|Bacteria,1G3HN@1117|Cyanobacteria	1117|Cyanobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3780386_1	635013.TherJR_0997	1.634e-162	548.0	COG0395@1|root,COG5001@1|root,COG5002@1|root,COG0395@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9
SRR25158397_k127_3780386_3	215803.DB30_1080	1.679e-69	243.0	COG3361@1|root,COG3361@2|Bacteria,1Q2C9@1224|Proteobacteria,437YP@68525|delta/epsilon subdivisions,2X38K@28221|Deltaproteobacteria,2YUU6@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158397_k127_3780386_5	457570.Nther_1438	2.99e-39	155.0	COG1215@1|root,COG1215@2|Bacteria,1UHZ3@1239|Firmicutes,24G8E@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_3780386_9	880073.Calab_1170	1.91e-05	54.0	COG5608@1|root,COG5608@2|Bacteria,2NS0K@2323|unclassified Bacteria	2|Bacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR25158397_k127_3780386_2	706587.Desti_1505	6.558e-77	274.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR25158397_k127_3780386_7	657322.FPR_11310	8.887e-08	65.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3WMXX@541000|Ruminococcaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158397_k127_3780386_6	1123354.AUDR01000014_gene979	5.837e-38	154.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,1KSFC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA methyltransferase	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158397_k127_3780386_0	1283299.AUKG01000003_gene204	1.25e-197	626.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158397_k127_3780386_4	234267.Acid_4996	7.218e-63	231.0	COG0726@1|root,COG0726@2|Bacteria,3Y51E@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158397_k127_3790634_2	1121920.AUAU01000031_gene1410	6.387e-66	228.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DapB_N,Gp_dh_C,Gp_dh_N
SRR25158397_k127_3790634_1	1121918.ARWE01000001_gene2325	3.185e-112	372.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,43S80@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158397_k127_3790634_3	240015.ACP_2169	3.523e-61	234.0	COG0285@1|root,COG0285@2|Bacteria,3Y3ZA@57723|Acidobacteria,2JI7I@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM Mur ligase	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158397_k127_3790634_0	1321778.HMPREF1982_03953	2.308e-175	559.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,267NA@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158397_k127_3790634_4	498761.HM1_1963	1.276e-46	176.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia	186801|Clostridia	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158397_k127_3790634_5	1128421.JAGA01000003_gene3091	3.996e-31	142.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_3790634_6	316274.Haur_4284	1.327e-06	61.0	COG1807@1|root,COG1807@2|Bacteria,2GBWH@200795|Chloroflexi,3756N@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_3802547_5	391038.Bphy_7366	1.21e-14	88.0	2998I@1|root,2ZWBS@2|Bacteria,1P7PM@1224|Proteobacteria,2W5QT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3802547_1	1123377.AUIV01000012_gene711	2.998e-128	413.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,1RNWP@1236|Gammaproteobacteria,1X5VT@135614|Xanthomonadales	135614|Xanthomonadales	JM	Glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR25158397_k127_3802547_2	936136.ARRT01000006_gene5965	2.016e-95	329.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,2TU81@28211|Alphaproteobacteria,4B8DF@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	CDP-glucose 4,6-dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158397_k127_3802547_0	1123368.AUIS01000027_gene1343	3.015e-153	495.0	COG0500@1|root,COG0500@2|Bacteria,1MVD1@1224|Proteobacteria,1RZDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158397_k127_3802547_3	1536775.H70737_28205	7.138e-61	222.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli,26Y1U@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC3	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158397_k127_3802547_4	977880.RALTA_B2140	1.195e-44	175.0	COG2242@1|root,COG2242@2|Bacteria,1R80H@1224|Proteobacteria,2VPPZ@28216|Betaproteobacteria,1KBN1@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158397_k127_3811314_14	487796.Flav2ADRAFT_1528	1.101e-10	63.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158397_k127_3811314_5	880073.Calab_1889	7.337e-51	201.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,SSF,SpoIIE
SRR25158397_k127_3811314_4	1179773.BN6_08690	5.813e-52	193.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4DYVB@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	chcB	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158397_k127_3811314_1	269799.Gmet_1782	1.819e-98	327.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
SRR25158397_k127_3811314_11	404589.Anae109_0085	9.194e-16	83.0	2C12A@1|root,33B7C@2|Bacteria,1NMUW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3811314_9	861299.J421_0966	1.787e-26	110.0	2E40T@1|root,32YXK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3811314_13	1278073.MYSTI_00694	3.141e-14	80.0	COG3682@1|root,COG3682@2|Bacteria,1N6UP@1224|Proteobacteria,43DK7@68525|delta/epsilon subdivisions,2X8RD@28221|Deltaproteobacteria,2Z0IP@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3811314_12	536019.Mesop_4244	1.168e-15	89.0	COG0671@1|root,COG0671@2|Bacteria,1RF6B@1224|Proteobacteria,2U8U5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158397_k127_3811314_0	671143.DAMO_2498	5.198e-149	481.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158397_k127_3811314_10	330214.NIDE2482	8.263e-21	107.0	COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158397_k127_3811314_8	240015.ACP_0264	1.125e-42	169.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158397_k127_3811314_7	316274.Haur_3896	3.651e-46	184.0	COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi,375F3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
SRR25158397_k127_3811314_16	383372.Rcas_2970	0.0009338	49.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3,DUF11,VCBS
SRR25158397_k127_3811314_15	1122138.AQUZ01000008_gene3682	0.0006039	53.0	COG1361@1|root,COG1361@2|Bacteria,2I8F1@201174|Actinobacteria,4DVAH@85009|Propionibacteriales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158397_k127_3811314_3	1499967.BAYZ01000084_gene3999	4.445e-89	301.0	COG1173@1|root,COG1173@2|Bacteria,2NQ14@2323|unclassified Bacteria	2|Bacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158397_k127_3811314_2	1499967.BAYZ01000076_gene838	6.488e-94	317.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158397_k127_3811314_6	1379698.RBG1_1C00001G1510	5.032e-48	179.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158397_k127_3812202_2	1366046.HIMB11_03236	1.277e-104	349.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,2TSPK@28211|Alphaproteobacteria,3ZG0A@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	Dihydroorotate dehydrogenase	preA	GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21,Fer4_4,Fer4_6
SRR25158397_k127_3812202_0	247490.KSU1_D0507	0.0	1935.0	COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3812202_1	247490.KSU1_D0506	6.499e-128	435.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158397_k127_3812202_5	215803.DB30_5882	1.414e-26	126.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158397_k127_3812202_4	247490.KSU1_D0505	6.459e-53	198.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
SRR25158397_k127_3812202_3	247490.KSU1_D0504	1.554e-57	224.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
SRR25158397_k127_3812202_6	33876.JNXY01000046_gene2016	6.08e-11	67.0	COG4977@1|root,COG4977@2|Bacteria,2I2TT@201174|Actinobacteria,4DI5I@85008|Micromonosporales	201174|Actinobacteria	K	Cupin	-	-	-	ko:K18991	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	Cupin_6,HTH_18
SRR25158397_k127_3817991_0	483219.LILAB_32760	8.663e-82	282.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
SRR25158397_k127_3817991_1	240015.ACP_2960	3.342e-51	185.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria,2JJ48@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158397_k127_3817991_3	395965.Msil_3484	1.505e-23	105.0	COG4113@1|root,COG4113@2|Bacteria,1NEE2@1224|Proteobacteria,2UJ3R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_3817991_2	345341.KUTG_02145	9.697e-24	106.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria,4E7I2@85010|Pseudonocardiales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_3862185_2	204669.Acid345_0609	1.741e-108	361.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158397_k127_3862185_11	395493.BegalDRAFT_1030	3.174e-06	60.0	COG2373@1|root,COG3405@1|root,COG3420@1|root,COG2373@2|Bacteria,COG3405@2|Bacteria,COG3420@2|Bacteria,1QV7E@1224|Proteobacteria	1224|Proteobacteria	V	TIGRFAM Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Big_3_5
SRR25158397_k127_3862185_0	1267534.KB906754_gene3786	6.297e-168	536.0	COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria,2JIVG@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158397_k127_3862185_10	632518.Calow_0263	4.478e-14	81.0	COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,24Q8D@186801|Clostridia,42IMJ@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_3862185_9	1242864.D187_008905	3.745e-20	98.0	COG2227@1|root,COG2227@2|Bacteria,1QX75@1224|Proteobacteria,43E3D@68525|delta/epsilon subdivisions,2X7AR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_3862185_3	314278.NB231_03220	1.444e-91	313.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,1RPPZ@1236|Gammaproteobacteria,1X0D4@135613|Chromatiales	135613|Chromatiales	V	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158397_k127_3862185_4	479431.Namu_4403	8.691e-69	243.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158397_k127_3862185_6	1123489.AUAN01000002_gene896	2.403e-44	171.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4H1VQ@909932|Negativicutes	909932|Negativicutes	G	hopanoid biosynthesis associated protein HpnK	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
SRR25158397_k127_3862185_1	1254432.SCE1572_47425	4.327e-118	389.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158397_k127_3862185_5	179408.Osc7112_0480	5.575e-65	235.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H7V1@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,GUN4,Pkinase,WD40
SRR25158397_k127_3862185_8	1078085.HMPREF1210_02842	2.024e-21	103.0	COG1660@1|root,COG1660@2|Bacteria,1V36M@1239|Firmicutes,4HFUJ@91061|Bacilli,26IH0@186818|Planococcaceae	91061|Bacilli	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33
SRR25158397_k127_3862185_7	1089550.ATTH01000001_gene410	1.621e-22	108.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1FJZE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158397_k127_3885428_18	264462.Bd0547	0.000321	51.0	COG4948@1|root,COG4948@2|Bacteria,1Q221@1224|Proteobacteria,43F0Z@68525|delta/epsilon subdivisions,2MUAR@213481|Bdellovibrionales,2WYMY@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Mandelate Racemase Muconate Lactonizing	-	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158397_k127_3885428_8	215803.DB30_6820	1.321e-73	259.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S4J@68525|delta/epsilon subdivisions,2WNH4@28221|Deltaproteobacteria,2YTUZ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158397_k127_3885428_3	1211035.CD30_17940	5.321e-132	425.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,3IWZD@400634|Lysinibacillus	91061|Bacilli	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158397_k127_3885428_14	1123070.KB899249_gene437	2.003e-21	109.0	COG2267@1|root,COG2267@2|Bacteria,46WQX@74201|Verrucomicrobia,2IUN2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Alpha/beta hydrolase family	-	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR25158397_k127_3885428_4	765952.PUV_20300	2.928e-101	351.0	COG1165@1|root,COG1165@2|Bacteria,2JG2A@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158397_k127_3885428_10	1396141.BATP01000047_gene3951	3.146e-45	184.0	COG1169@1|root,COG1169@2|Bacteria,46YW2@74201|Verrucomicrobia,2IU6K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158397_k127_3885428_7	264462.Bd3487	2.856e-75	276.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2MT3P@213481|Bdellovibrionales,2WNJ6@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158397_k127_3885428_12	504472.Slin_2795	3.761e-31	141.0	COG1506@1|root,COG1506@2|Bacteria,4P5XA@976|Bacteroidetes	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3885428_1	379066.GAU_1367	5.935e-203	662.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1ZSSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
SRR25158397_k127_3885428_9	269798.CHU_0074	6.38e-48	196.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158397_k127_3885428_2	379066.GAU_1368	3.908e-132	433.0	COG0498@1|root,COG0498@2|Bacteria,1ZSVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158397_k127_3885428_17	324831.LGAS_0732	0.0001335	49.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,4HKPP@91061|Bacilli,3F59N@33958|Lactobacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
SRR25158397_k127_3885428_11	861299.J421_2064	5.079e-32	128.0	COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
SRR25158397_k127_3885428_16	309807.SRU_2822	7.089e-07	60.0	COG2968@1|root,COG2968@2|Bacteria,4P8H6@976|Bacteroidetes,1FJN4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SRR25158397_k127_3885428_6	546414.Deide_03660	3.288e-90	325.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158397_k127_3885428_0	671143.DAMO_0012	6.361e-204	651.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158397_k127_3885428_15	1032480.MLP_34460	8.756e-08	64.0	28MCN@1|root,2ZAQR@2|Bacteria,2GXXM@201174|Actinobacteria,4DW15@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3885428_13	553217.ENHAE0001_2005	1.655e-26	111.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,1SG7J@1236|Gammaproteobacteria,3NPHX@468|Moraxellaceae	1236|Gammaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158397_k127_3885428_5	1232410.KI421412_gene116	1.292e-91	316.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42NZP@68525|delta/epsilon subdivisions,2WKZA@28221|Deltaproteobacteria,43S59@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158397_k127_390555_8	278963.ATWD01000001_gene2665	1.276e-36	144.0	COG0640@1|root,COG0640@2|Bacteria,3Y7J1@57723|Acidobacteria,2JMRU@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158397_k127_390555_5	448385.sce3213	5.019e-65	235.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158397_k127_390555_10	251221.35212252	2.231e-11	71.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ,Metal_resist
SRR25158397_k127_390555_3	518766.Rmar_2600	9.179e-92	310.0	COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,1FJNW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158397_k127_390555_0	543728.Vapar_1657	1.346e-170	550.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2VIKV@28216|Betaproteobacteria,4AESP@80864|Comamonadaceae	28216|Betaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158397_k127_390555_2	290397.Adeh_2943	6.471e-124	433.0	COG0784@1|root,COG3437@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158397_k127_390555_11	571.MC52_17190	0.0002151	49.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RPNH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	basR	GO:0000156,GO:0000160,GO:0003674,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07771	ko01503,ko02020,map01503,map02020	M00451,M00721,M00722	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_390555_9	1121438.JNJA01000001_gene2231	3.745e-25	110.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42VTR@68525|delta/epsilon subdivisions,2X5PP@28221|Deltaproteobacteria,2MGU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158397_k127_390555_4	234267.Acid_4535	7.27e-70	263.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158397_k127_390555_7	861299.J421_2234	1.81e-49	183.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	ykuD	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
SRR25158397_k127_390555_12	863365.XHC_0509	0.0003284	46.0	COG2906@1|root,COG2906@2|Bacteria,1PQES@1224|Proteobacteria,1T6UB@1236|Gammaproteobacteria,1X85W@135614|Xanthomonadales	135614|Xanthomonadales	P	bacterioferritin	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
SRR25158397_k127_390555_6	290397.Adeh_0191	2.495e-58	210.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42SK2@68525|delta/epsilon subdivisions,2WPB3@28221|Deltaproteobacteria,2Z0CU@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158397_k127_390555_1	861299.J421_4478	5.331e-152	504.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158397_k127_3925774_0	404589.Anae109_4348	1.254e-149	485.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158397_k127_3925774_2	1192034.CAP_6532	9.893e-42	159.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2WQ7W@28221|Deltaproteobacteria,2Z370@29|Myxococcales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158397_k127_3925774_3	234267.Acid_0109	1.708e-29	121.0	COG0838@1|root,COG0838@2|Bacteria,3Y5CV@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158397_k127_3925774_7	313612.L8106_18507	1.279e-07	63.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria,1HCQQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158397_k127_3925774_4	1424334.W822_09855	2.184e-24	107.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,3T49W@506|Alcaligenaceae	28216|Betaproteobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158397_k127_3925774_1	449447.MAE_12430	3.806e-72	274.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
SRR25158397_k127_3925774_5	1500893.JQNB01000001_gene1536	1.53e-14	88.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1SG73@1236|Gammaproteobacteria,1X5NU@135614|Xanthomonadales	135614|Xanthomonadales	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,He_PIG
SRR25158397_k127_3925774_6	1121946.AUAX01000017_gene5030	3.035e-12	77.0	COG0726@1|root,COG1404@1|root,COG0726@2|Bacteria,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4DADU@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Inhibitor_I9,P_proprotein,Peptidase_S8
SRR25158397_k127_3930583_8	1123377.AUIV01000008_gene1373	1.693e-27	130.0	COG2909@1|root,COG4995@1|root,COG2909@2|Bacteria,COG4995@2|Bacteria,1QUP3@1224|Proteobacteria,1SJ9T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158397_k127_3930583_5	861299.J421_5806	1.021e-82	301.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GUN4,GUN4_N,Peptidase_C13,Peptidase_C14,TPR_10
SRR25158397_k127_3930583_0	868131.MSWAN_0600	0.0	1132.0	COG1112@1|root,arCOG00803@2157|Archaea,2XUVX@28890|Euryarchaeota,23NQQ@183925|Methanobacteria	183925|Methanobacteria	L	Protein of unknown function (DUF4011)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011
SRR25158397_k127_3930583_3	525897.Dbac_1067	2.998e-125	415.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,2MDZ6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158397_k127_3930583_6	1123242.JH636435_gene2864	5.541e-50	187.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
SRR25158397_k127_3930583_10	863365.XHC_1346	1.375e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,1RCMS@1224|Proteobacteria,1S3I3@1236|Gammaproteobacteria,1XC72@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rfaY	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_3930583_4	1123367.C666_13075	8.563e-115	383.0	COG0457@1|root,COG0457@2|Bacteria,1NY1N@1224|Proteobacteria,2VWNJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
SRR25158397_k127_3930583_7	240292.Ava_4731	2.012e-48	199.0	2BKA1@1|root,32EQ8@2|Bacteria,1GJ4Q@1117|Cyanobacteria,1HQEC@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3930583_2	103690.17131134	1.177e-201	659.0	COG1511@1|root,COG1511@2|Bacteria,1G29D@1117|Cyanobacteria,1HQZW@1161|Nostocales	1117|Cyanobacteria	S	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin_2
SRR25158397_k127_3930583_9	240292.Ava_4733	5.002e-27	124.0	COG2304@1|root,COG2304@2|Bacteria,1GE29@1117|Cyanobacteria,1HQQ8@1161|Nostocales	1117|Cyanobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158397_k127_3930583_12	1123376.AUIU01000016_gene283	3.087e-05	57.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158397_k127_3930583_11	1121015.N789_03605	1.147e-07	57.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158397_k127_3930583_1	671143.DAMO_0533	3.486e-264	830.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158397_k127_3942313_0	35841.BT1A1_3096	3.847e-52	192.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,1ZBVN@1386|Bacillus	91061|Bacilli	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158397_k127_3942313_2	1348663.KCH_05120	4.153e-08	66.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158397_k127_3942313_1	1499967.BAYZ01000074_gene2101	9.222e-24	113.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
SRR25158397_k127_3945378_4	1307436.PBF_05388	5.076e-06	51.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_3945378_2	1121939.L861_22705	3.604e-38	150.0	2CZ4M@1|root,32T5I@2|Bacteria,1N344@1224|Proteobacteria,1SRM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3945378_0	251221.35214536	7.898e-187	608.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1G4UJ@1117|Cyanobacteria	1117|Cyanobacteria	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158397_k127_3945378_1	1101191.KI912577_gene308	1.69e-64	230.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,2U7PM@28211|Alphaproteobacteria,1JUKZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158397_k127_3958614_7	1047013.AQSP01000028_gene2076	2.688e-13	83.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
SRR25158397_k127_3958614_2	379066.GAU_2720	2.449e-102	368.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158397_k127_3958614_3	1416752.AYME01000005_gene1710	1.236e-29	135.0	COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2GM2V@201174|Actinobacteria,4FPG2@85023|Microbacteriaceae	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII,SNF2_N
SRR25158397_k127_3958614_0	671143.DAMO_3009	3.016e-129	429.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_3958614_5	1163409.UUA_14424	6.696e-28	130.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1SDD5@1236|Gammaproteobacteria,1X6IQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158397_k127_3958614_8	877414.ATWA01000034_gene1270	1.311e-09	69.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,268BT@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158397_k127_3958614_6	545276.KB898725_gene651	5.336e-26	115.0	COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales	135613|Chromatiales	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158397_k127_3958614_1	1437425.CSEC_1391	1.5e-114	386.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158397_k127_3958614_4	1033743.CAES01000033_gene1017	3.827e-28	120.0	COG4293@1|root,COG4293@2|Bacteria,1V7WR@1239|Firmicutes,4HJQG@91061|Bacilli,26XJ2@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158397_k127_395918_9	1996.JOFO01000014_gene6755	0.0006648	44.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria,4EINC@85012|Streptosporangiales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158397_k127_395918_1	204669.Acid345_4432	7.331e-159	524.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
SRR25158397_k127_395918_0	1089547.KB913013_gene2767	5.334e-210	667.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_395918_5	1469557.JSWF01000025_gene1319	7.232e-19	100.0	2AVBG@1|root,31M2S@2|Bacteria,4NQIJ@976|Bacteroidetes,1I3P4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_395918_2	266834.SMc01745	3.76e-63	222.0	COG1011@1|root,COG1011@2|Bacteria,1RKHU@1224|Proteobacteria,2U9I0@28211|Alphaproteobacteria,4BM14@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158397_k127_395918_3	1144275.COCOR_06747	1.644e-24	112.0	COG1413@1|root,COG1413@2|Bacteria,1NB0I@1224|Proteobacteria	1224|Proteobacteria	C	response to radiation	yibA	GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0033554,GO:0042221,GO:0046677,GO:0050896,GO:0051716	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158397_k127_395918_6	1122604.JONR01000007_gene2934	1.637e-17	94.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1MY07@1224|Proteobacteria	1224|Proteobacteria	O	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_395918_7	616991.JPOO01000001_gene2934	3.554e-15	86.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_395918_4	639282.DEFDS_0877	6.932e-20	105.0	2CNNA@1|root,32SHE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3966330_9	443143.GM18_3425	1.773e-27	121.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
SRR25158397_k127_3966330_4	1268237.G114_00335	4.965e-65	234.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1Y3RC@135624|Aeromonadales	135624|Aeromonadales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158397_k127_3966330_2	204669.Acid345_0995	1.082e-129	441.0	COG3191@1|root,COG3191@2|Bacteria,3Y699@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158397_k127_3966330_6	880073.Calab_2853	8.412e-61	234.0	COG3437@1|root,COG3437@2|Bacteria,2NPBP@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRR25158397_k127_3966330_5	1123508.JH636439_gene803	1.566e-63	242.0	COG3437@1|root,COG3437@2|Bacteria,2IYS1@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
SRR25158397_k127_3966330_7	318424.EU78_04755	9.023e-54	195.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria,239GM@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158397_k127_3966330_12	1254432.SCE1572_51590	2.068e-17	94.0	COG3239@1|root,COG3239@2|Bacteria,1PEHR@1224|Proteobacteria,439TU@68525|delta/epsilon subdivisions,2X3GW@28221|Deltaproteobacteria,2YW1Q@29|Myxococcales	28221|Deltaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158397_k127_3966330_0	518766.Rmar_2194	1.55e-156	514.0	COG0160@1|root,COG0160@2|Bacteria,4NGPB@976|Bacteroidetes,1FITF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158397_k127_3966330_1	1254432.SCE1572_41455	2.554e-138	452.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158397_k127_3966330_14	1353276.JADR01000001_gene373	0.000752	48.0	COG3047@1|root,COG3047@2|Bacteria,4NPKA@976|Bacteroidetes,1I1SB@117743|Flavobacteriia	976|Bacteroidetes	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158397_k127_3966330_10	1265505.ATUG01000002_gene1528	1.079e-22	116.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,42Q0T@68525|delta/epsilon subdivisions,2WM1J@28221|Deltaproteobacteria,2MKK9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
SRR25158397_k127_3966330_8	886293.Sinac_7034	3.384e-47	197.0	COG4625@1|root,COG4625@2|Bacteria,2J0EF@203682|Planctomycetes	2|Bacteria	S	Bacterial Ig-like domain (group 3)	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,Big_3_5,Cadherin-like,Calx-beta,DUF4347,He_PIG,PATR,TIG,fn3
SRR25158397_k127_3966330_11	251229.Chro_0714	1.42e-22	116.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria,3VJ7N@52604|Pleurocapsales	1117|Cyanobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
SRR25158397_k127_3966330_3	383372.Rcas_0286	4.69e-66	233.0	COG1011@1|root,COG1011@2|Bacteria,2G916@200795|Chloroflexi,377HS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158397_k127_3966351_0	330214.NIDE4018	7.73e-207	659.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158397_k127_3966351_4	196367.JNFG01000030_gene8544	1.541e-13	79.0	COG1595@1|root,COG1595@2|Bacteria,1PT8E@1224|Proteobacteria,2W1XX@28216|Betaproteobacteria,1K2WI@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_3966351_2	1123024.AUII01000025_gene2129	1.651e-48	184.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IH0Y@201174|Actinobacteria,4E30J@85010|Pseudonocardiales	201174|Actinobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1
SRR25158397_k127_3966351_3	1340493.JNIF01000003_gene1293	9.019e-27	125.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
SRR25158397_k127_3966351_5	1242864.D187_007053	1.026e-05	59.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_3966351_1	215803.DB30_6944	5.739e-186	641.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2X2JP@28221|Deltaproteobacteria,2YY11@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
SRR25158397_k127_3972250_2	1122604.JONR01000009_gene2348	4.84e-73	249.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,1X64X@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
SRR25158397_k127_3972250_3	1121377.KB906402_gene3200	1.119e-64	237.0	COG0608@1|root,COG0608@2|Bacteria	2|Bacteria	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158397_k127_3972250_0	1123242.JH636434_gene3349	8.162e-109	382.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	2|Bacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	DNA_pol_A_exo1,FtsK_SpoIIIE,PDDEXK_1
SRR25158397_k127_3972250_5	489825.LYNGBM3L_20710	1.468e-18	103.0	COG1485@1|root,COG1485@2|Bacteria,1G30U@1117|Cyanobacteria,1HI22@1150|Oscillatoriales	1117|Cyanobacteria	S	Reduces the stability of FtsZ polymers in the presence of ATP	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158397_k127_3972250_1	867900.Celly_0896	1.137e-100	342.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1HX3P@117743|Flavobacteriia	976|Bacteroidetes	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158397_k127_397922_4	1379270.AUXF01000007_gene875	1.529e-12	78.0	COG0656@1|root,COG0656@2|Bacteria,1ZURF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158397_k127_397922_3	379066.GAU_0898	2.87e-32	132.0	COG2318@1|root,COG2318@2|Bacteria,1ZU3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_397922_2	1379698.RBG1_1C00001G0290	2.023e-72	272.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
SRR25158397_k127_397922_0	240015.ACP_1025	1.081e-161	517.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158397_k127_397922_1	401526.TcarDRAFT_1687	2.069e-92	323.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H1WI@909932|Negativicutes	909932|Negativicutes	E	LAO AO transport system	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158397_k127_398615_6	1207063.P24_17427	1.227e-49	188.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,2UFDW@28211|Alphaproteobacteria,2JYGG@204441|Rhodospirillales	204441|Rhodospirillales	S	ImpA, N-terminal, type VI secretion system	-	-	-	-	-	-	-	-	-	-	-	-	ImpA_N
SRR25158397_k127_398615_4	1120999.JONM01000007_gene1834	4.833e-64	224.0	COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,2VQ69@28216|Betaproteobacteria,2KR05@206351|Neisseriales	206351|Neisseriales	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA
SRR25158397_k127_398615_1	205922.Pfl01_3407	5.806e-237	742.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1YT09@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	type VI secretion protein	evpB	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
SRR25158397_k127_398615_5	1550073.JROH01000002_gene741	3.472e-51	186.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2U1NF@28211|Alphaproteobacteria,2K4XV@204457|Sphingomonadales	204457|Sphingomonadales	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SRR25158397_k127_398615_7	448385.sce9339	4.553e-25	111.0	COG3518@1|root,COG3518@2|Bacteria,1Q2KF@1224|Proteobacteria,433UA@68525|delta/epsilon subdivisions,2X3H1@28221|Deltaproteobacteria,2YW24@29|Myxococcales	28221|Deltaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
SRR25158397_k127_398615_2	1192034.CAP_6448	1.404e-172	561.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,42PR4@68525|delta/epsilon subdivisions,2WJCN@28221|Deltaproteobacteria,2YU04@29|Myxococcales	28221|Deltaproteobacteria	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
SRR25158397_k127_398615_3	330214.NIDE1984	6.672e-67	244.0	COG3520@1|root,COG3520@2|Bacteria,3J18D@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:T6SS_VasB	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
SRR25158397_k127_398615_0	330214.NIDE1985	6.73e-285	899.0	COG0542@1|root,COG0542@2|Bacteria,3J0W0@40117|Nitrospirae	40117|Nitrospirae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
SRR25158397_k127_398615_8	1121929.KB898664_gene1248	7.173e-13	75.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,4716Q@74385|Gracilibacillus	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158397_k127_398917_1	84531.JMTZ01000030_gene145	2.674e-88	306.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RQ1P@1236|Gammaproteobacteria,1X5A0@135614|Xanthomonadales	135614|Xanthomonadales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158397_k127_398917_6	1340493.JNIF01000003_gene1849	3.698e-05	55.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_398917_5	350688.Clos_2202	5.042e-49	190.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,36HZ1@31979|Clostridiaceae	186801|Clostridia	S	Spore maturation protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
SRR25158397_k127_398917_2	1408422.JHYF01000014_gene260	1.659e-66	233.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,36E11@31979|Clostridiaceae	186801|Clostridia	S	Spore maturation protein	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
SRR25158397_k127_398917_3	1122138.AQUZ01000028_gene706	5.56e-59	218.0	COG0500@1|root,COG2226@2|Bacteria,2HF00@201174|Actinobacteria,4DVYR@85009|Propionibacteriales	201174|Actinobacteria	Q	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158397_k127_398917_0	1340493.JNIF01000004_gene652	1.236e-238	756.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158397_k127_398917_7	1463885.KL578365_gene2699	0.0006641	50.0	2E0DR@1|root,32W0E@2|Bacteria,2IFJC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3993543_3	1172188.KB911824_gene3399	2.221e-68	247.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_3993543_1	196162.Noca_1788	2.963e-182	588.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4DTHI@85009|Propionibacteriales	201174|Actinobacteria	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158397_k127_3993543_0	883126.HMPREF9710_00104	2.726e-230	737.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2VKWR@28216|Betaproteobacteria,476VV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_3993543_2	639030.JHVA01000001_gene1971	8.032e-84	285.0	COG0748@1|root,COG0748@2|Bacteria,3Y2Q3@57723|Acidobacteria,2JMJG@204432|Acidobacteriia	204432|Acidobacteriia	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Pyrid_oxidase_2
SRR25158397_k127_399833_4	378806.STAUR_5750	2.96e-31	125.0	COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,42ZR1@68525|delta/epsilon subdivisions,2WV1F@28221|Deltaproteobacteria,2YZWT@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158397_k127_399833_5	1385511.N783_05550	4.208e-17	89.0	COG1280@1|root,COG1280@2|Bacteria,1VV0S@1239|Firmicutes,4HVTB@91061|Bacilli,2YAC6@289201|Pontibacillus	91061|Bacilli	E	Amino acid transporter	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158397_k127_399833_6	439235.Dalk_1780	4.892e-05	54.0	COG3047@1|root,COG3047@2|Bacteria,1Q8PV@1224|Proteobacteria,437GB@68525|delta/epsilon subdivisions,2X2NY@28221|Deltaproteobacteria,2MP63@213118|Desulfobacterales	2|Bacteria	M	OmpW family	ompW	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K07275,ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OmpW
SRR25158397_k127_399833_3	1006000.GKAS_00215	2.665e-39	169.0	COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	cysL_1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158397_k127_399833_2	234267.Acid_1102	1.101e-45	186.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158397_k127_399833_1	204669.Acid345_3061	4.997e-67	236.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria,2JMC0@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_399833_0	661478.OP10G_4632	2.516e-174	580.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158397_k127_4003070_5	1120965.AUBV01000014_gene1249	8.04e-10	61.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158397_k127_4003070_3	215803.DB30_8463	7.099e-36	147.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,42TM1@68525|delta/epsilon subdivisions,2WRSH@28221|Deltaproteobacteria,2YVKN@29|Myxococcales	28221|Deltaproteobacteria	U	Small Multidrug Resistance protein	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR25158397_k127_4003070_0	1047013.AQSP01000083_gene1192	2.847e-154	501.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_4003070_1	234267.Acid_1646	1.311e-111	394.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
SRR25158397_k127_4003070_2	316067.Geob_1393	1.374e-50	207.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,43T7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
SRR25158397_k127_4003070_4	1242864.D187_003683	4.105e-14	88.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_4003248_4	290397.Adeh_1905	8.316e-63	222.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,437B2@68525|delta/epsilon subdivisions,2X2FR@28221|Deltaproteobacteria,2Z0QW@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158397_k127_4003248_3	1169144.KB910924_gene629	3.62e-63	235.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158397_k127_4003248_5	696369.KI912183_gene226	6.154e-59	214.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,261MS@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
SRR25158397_k127_4003248_2	204669.Acid345_3011	9.208e-117	385.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158397_k127_4003248_0	1122137.AQXF01000003_gene2417	2.239e-163	534.0	COG2234@1|root,COG2234@2|Bacteria,1NVWC@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158397_k127_4003248_1	1121920.AUAU01000018_gene1806	1.447e-139	452.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180,2.3.1.262	ko:K00648,ko:K18003	ko00061,ko00405,ko01100,ko01130,ko01212,ko02024,ko02025,map00061,map00405,map01100,map01130,map01212,map02024,map02025	M00082,M00083	R10707,R11586,R11587,R11588	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158397_k127_4010302_5	404589.Anae109_1481	2.073e-14	79.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158397_k127_4010302_7	1187851.A33M_1650	2.273e-06	59.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
SRR25158397_k127_4010302_1	871963.Desdi_2492	1.01e-102	347.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158397_k127_4010302_2	316067.Geob_1233	8.962e-80	285.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,43TZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
SRR25158397_k127_4010302_3	96561.Dole_0513	1.742e-60	217.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158397_k127_4010302_4	234267.Acid_6018	3.645e-16	89.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K02487,ko:K03832,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02000,ko02022,ko02035	2.C.1.1	-	-	CarbopepD_reg_2,FabA,KAsynt_C_assoc,Ketoacyl-synt_C,TonB_2,TonB_C,ketoacyl-synt
SRR25158397_k127_4010302_0	1089548.KI783301_gene190	1.113e-203	651.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,3WFDZ@539002|Bacillales incertae sedis	91061|Bacilli	C	Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158397_k127_4010302_6	1336233.JAEH01000018_gene3100	1.109e-11	71.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria,2QAV5@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4013124_1	861299.J421_0916	5.61e-125	414.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_4013124_3	861299.J421_0915	1.299e-110	376.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_4013124_2	1232410.KI421420_gene3155	7.207e-112	370.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,43S9D@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Initiation factor 2 subunit family	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
SRR25158397_k127_4013124_0	246194.CHY_0280	6.477e-137	443.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158397_k127_4013124_4	1382304.JNIL01000001_gene2895	3.793e-110	380.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,277XX@186823|Alicyclobacillaceae	91061|Bacilli	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
SRR25158397_k127_4013124_6	204669.Acid345_2026	2.174e-28	121.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria,2JJIG@204432|Acidobacteriia	204432|Acidobacteriia	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
SRR25158397_k127_4013124_5	290397.Adeh_3692	1.561e-34	145.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158397_k127_4034443_1	1385517.N800_13240	2.655e-118	396.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1X2Y6@135614|Xanthomonadales	135614|Xanthomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_4034443_3	314287.GB2207_00960	4.35e-82	289.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,1SJUT@1236|Gammaproteobacteria,1J957@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_4034443_2	234267.Acid_6580	5.23e-90	312.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria	234267.Acid_6580|-	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158397_k127_4034443_0	1121920.AUAU01000008_gene1537	9.954e-149	477.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158397_k127_4034443_4	101510.RHA1_ro00069	4.299e-23	109.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4G081@85025|Nocardiaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158397_k127_4034443_5	570952.ATVH01000016_gene2350	7.917e-12	76.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JPCT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158397_k127_4041222_6	459495.SPLC1_S550310	5.406e-15	80.0	COG0500@1|root,COG0500@2|Bacteria,1G1YB@1117|Cyanobacteria,1HA07@1150|Oscillatoriales	1117|Cyanobacteria	Q	Cyclopropane fatty acid synthase and related methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_4041222_0	1121123.AUAO01000003_gene2394	1.87e-144	469.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KIF5@204458|Caulobacterales	204458|Caulobacterales	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
SRR25158397_k127_4041222_3	1095769.CAHF01000006_gene1870	1.663e-84	289.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2VKPI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158397_k127_4041222_4	351160.RCIX701	3.912e-39	156.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158397_k127_4041222_2	1463861.JNXE01000008_gene9433	1.207e-104	353.0	COG2008@1|root,COG2008@2|Bacteria,2IBCJ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158397_k127_4041222_8	1219049.SP5_022_00300	0.0001622	48.0	COG1629@1|root,COG1629@2|Bacteria,1QVFQ@1224|Proteobacteria,2TWDY@28211|Alphaproteobacteria,2KESA@204457|Sphingomonadales	204457|Sphingomonadales	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_4041222_5	1173023.KE650771_gene723	3.153e-18	91.0	COG2442@1|root,COG2442@2|Bacteria,1G9UJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_4041222_7	118161.KB235924_gene6503	4.172e-14	82.0	COG4634@1|root,COG4634@2|Bacteria,1G86P@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
SRR25158397_k127_4041222_1	1254432.SCE1572_03315	7.661e-107	357.0	COG0654@1|root,COG0654@2|Bacteria,1N7Z4@1224|Proteobacteria,43BXN@68525|delta/epsilon subdivisions,2X78F@28221|Deltaproteobacteria,2YU0J@29|Myxococcales	28221|Deltaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4050135_5	497964.CfE428DRAFT_3647	7.029e-63	222.0	COG1236@1|root,COG1793@1|root,COG1236@2|Bacteria,COG1793@2|Bacteria,46SCR@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA ligase N terminus	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K07577,ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N,RMMBL
SRR25158397_k127_4050135_7	259536.Psyc_1775	1.076e-17	83.0	COG1983@1|root,COG1983@2|Bacteria,1NAUA@1224|Proteobacteria,1SD7E@1236|Gammaproteobacteria,3NPCM@468|Moraxellaceae	1236|Gammaproteobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
SRR25158397_k127_4050135_8	525897.Dbac_1883	4.635e-09	63.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MBQT@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_4050135_3	765420.OSCT_1841	7.434e-101	340.0	COG2021@1|root,COG2021@2|Bacteria,2G5JD@200795|Chloroflexi,374TP@32061|Chloroflexia	32061|Chloroflexia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158397_k127_4050135_9	497964.CfE428DRAFT_5120	1.241e-07	63.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,EAL,HATPase_c,HisKA,MASE3,PAS_4,Response_reg
SRR25158397_k127_4050135_1	1380394.JADL01000003_gene4837	4.869e-129	427.0	COG1816@1|root,COG1816@2|Bacteria,1R6Q8@1224|Proteobacteria,2U0BN@28211|Alphaproteobacteria,2JQP7@204441|Rhodospirillales	204441|Rhodospirillales	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158397_k127_4050135_2	543632.JOJL01000014_gene9230	7.716e-104	366.0	2EX9M@1|root,33QKC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4050135_0	204669.Acid345_3340	8.728e-254	807.0	COG0550@1|root,COG0550@2|Bacteria,3Y343@57723|Acidobacteria,2JHPW@204432|Acidobacteriia	204432|Acidobacteriia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158397_k127_4050135_6	497964.CfE428DRAFT_2436	1.568e-23	113.0	2EEXH@1|root,338QV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
SRR25158397_k127_4050135_4	626887.J057_21920	1.754e-64	227.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRR1@1236|Gammaproteobacteria,4646F@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_4056403_7	1319815.HMPREF0202_01388	1.755e-11	75.0	COG2849@1|root,COG2849@2|Bacteria,378B9@32066|Fusobacteria	32066|Fusobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
SRR25158397_k127_4056403_2	1121028.ARQE01000005_gene2826	3.65e-55	195.0	COG4104@1|root,COG4104@2|Bacteria,1N2DB@1224|Proteobacteria	1224|Proteobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
SRR25158397_k127_4056403_1	1123242.JH636435_gene1504	2.778e-85	301.0	COG0500@1|root,COG2226@2|Bacteria,2J1W2@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4056403_0	1242864.D187_000567	2.772e-160	532.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,2YU2Q@29|Myxococcales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
SRR25158397_k127_4056403_6	1297742.A176_00925	2.2e-12	75.0	2A461@1|root,30SR2@2|Bacteria,1PC3D@1224|Proteobacteria,433A7@68525|delta/epsilon subdivisions,2WXTE@28221|Deltaproteobacteria,2YW5Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4056403_4	448385.sce6671	2.159e-25	117.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.5.1.28	ko:K01447,ko:K07126,ko:K13582	ko04112,map04112	-	R04112	RC00064,RC00141	ko00000,ko00001,ko01000	-	-	-	LysM,PG_binding_1,Sel1
SRR25158397_k127_4056403_5	1265505.ATUG01000001_gene4607	4.342e-15	87.0	2DY7W@1|root,348JE@2|Bacteria,1P2KV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4056403_3	1286093.C266_09769	3.214e-29	119.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,1K0GR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158397_k127_407053_5	1122604.JONR01000036_gene3800	2.917e-18	86.0	COG1669@1|root,COG1669@2|Bacteria,1N81V@1224|Proteobacteria,1SD9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_407053_2	1173022.Cri9333_3171	3.259e-23	101.0	COG2361@1|root,COG2361@2|Bacteria,1GA5P@1117|Cyanobacteria,1HDVY@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158397_k127_407053_4	1122604.JONR01000036_gene3800	2.276e-21	97.0	COG1669@1|root,COG1669@2|Bacteria,1N81V@1224|Proteobacteria,1SD9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_407053_7	1089551.KE386572_gene3097	1.113e-16	85.0	COG1669@1|root,COG1669@2|Bacteria,1N81V@1224|Proteobacteria,2UGQ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158397_k127_407053_3	1173022.Cri9333_3171	2.559e-22	101.0	COG2361@1|root,COG2361@2|Bacteria,1GA5P@1117|Cyanobacteria,1HDVY@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158397_k127_407053_6	1122223.KB890696_gene10	5.086e-18	87.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_407053_1	498761.HM1_2362	1.262e-51	198.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158397_k127_407053_8	1123511.KB905841_gene1348	1.721e-08	65.0	2ASQ0@1|root,31I4U@2|Bacteria,1VZD6@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_407053_0	373903.Hore_15730	1.101e-63	227.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WAD7@53433|Halanaerobiales	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158397_k127_4071050_3	945713.IALB_1403	2.909e-144	465.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	rfbB	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158397_k127_4071050_2	269796.Rru_A2116	5.155e-161	520.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158397_k127_4071050_12	1270193.JARP01000001_gene2265	3.192e-19	101.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1IIYR@117743|Flavobacteriia,2P0H7@237|Flavobacterium	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158397_k127_4071050_6	518766.Rmar_2343	1.875e-79	274.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1FIW0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158397_k127_4071050_7	671143.DAMO_2629	1.372e-68	241.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158397_k127_4071050_1	96561.Dole_0908	6.686e-164	544.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MIC2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158397_k127_4071050_0	234267.Acid_1201	6.772e-181	595.0	COG3591@1|root,COG3591@2|Bacteria,3Y2TU@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158397_k127_4071050_4	1129374.AJE_07546	1.318e-124	415.0	COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria,1RZK8@1236|Gammaproteobacteria,465YN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4071050_8	857087.Metme_4167	1.618e-52	214.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1XGAS@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158397_k127_4071050_10	1379701.JPJC01000249_gene811	1.154e-45	179.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2KD4D@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_4071050_9	1122604.JONR01000033_gene34	3.725e-49	186.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158397_k127_4071050_5	1227739.Hsw_2460	1.188e-111	383.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158397_k127_4071050_11	903814.ELI_1007	2.721e-19	96.0	2CID0@1|root,33KCN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4074735_3	1121127.JAFA01000026_gene2892	1.857e-41	160.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,LysM,PG_binding_1
SRR25158397_k127_4074735_4	246197.MXAN_0293	2.88e-33	140.0	COG5207@1|root,COG5207@2|Bacteria,1RHKT@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158397_k127_4074735_2	981369.JQMJ01000004_gene4297	1.691e-52	196.0	COG0500@1|root,COG2226@2|Bacteria,2HMMP@201174|Actinobacteria,2NG97@228398|Streptacidiphilus	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158397_k127_4074735_0	1121924.ATWH01000006_gene1737	1.931e-130	435.0	COG0031@1|root,COG0031@2|Bacteria,2IA0Z@201174|Actinobacteria,4FR72@85023|Microbacteriaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158397_k127_4074735_5	1408321.JNJD01000007_gene439	2.935e-15	91.0	COG4403@1|root,COG4403@2|Bacteria,1V37N@1239|Firmicutes,24GB0@186801|Clostridia	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158397_k127_4074735_1	1254432.SCE1572_29395	1.902e-77	275.0	COG2312@1|root,COG2312@2|Bacteria,1NEZB@1224|Proteobacteria,433VP@68525|delta/epsilon subdivisions,2X3PC@28221|Deltaproteobacteria,2YWR8@29|Myxococcales	28221|Deltaproteobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg,Erythro_esteras
SRR25158397_k127_4086607_1	1123371.ATXH01000006_gene845	6.376e-54	215.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,2GIQR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Response_reg
SRR25158397_k127_4086607_2	1198452.Jab_2c12290	1.785e-51	190.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VHQ0@28216|Betaproteobacteria,475IN@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_4086607_3	1183438.GKIL_1487	2.646e-33	137.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria	1117|Cyanobacteria	T	Diguanylate cyclase with PAS PAC and GAF sensors	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158397_k127_4086607_4	1449068.JMLQ01000012_gene1529	1.543e-22	113.0	COG2200@1|root,COG2200@2|Bacteria,2I2Q6@201174|Actinobacteria,4FZ7V@85025|Nocardiaceae	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SRR25158397_k127_4086607_0	941449.dsx2_1429	1.62e-100	343.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_4087066_4	448385.sce1844	0.0008231	51.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
SRR25158397_k127_4087066_3	1090319.KE386571_gene437	0.0005305	53.0	2EBPI@1|root,335PM@2|Bacteria,1R3KC@1224|Proteobacteria,2UNS1@28211|Alphaproteobacteria,2K160@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4087066_1	290397.Adeh_4303	3.109e-34	152.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158397_k127_4087066_0	309801.trd_1461	1.226e-86	297.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRR25158397_k127_4087066_2	1242864.D187_010427	6.344e-11	68.0	2E458@1|root,32Z1A@2|Bacteria,1PAGT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_408804_6	404589.Anae109_0646	1.097e-25	109.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5EQ@28221|Deltaproteobacteria,2Z35B@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158397_k127_408804_1	207559.Dde_1627	2.288e-84	317.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M99S@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
SRR25158397_k127_408804_0	290397.Adeh_0603	5.39e-141	478.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42Y7C@68525|delta/epsilon subdivisions,2WTJH@28221|Deltaproteobacteria,2YXEJ@29|Myxococcales	28221|Deltaproteobacteria	NT	Chemotaxis protein histidine kinase and related kinases	cheA2	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158397_k127_408804_4	1121920.AUAU01000022_gene2494	1.383e-33	140.0	COG1871@1|root,COG1871@2|Bacteria,3Y5E5@57723|Acidobacteria	57723|Acidobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
SRR25158397_k127_408804_5	1232410.KI421413_gene806	1.257e-29	133.0	COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
SRR25158397_k127_408804_3	404589.Anae109_0650	4.266e-46	171.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria,2Z0DC@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
SRR25158397_k127_408804_2	555088.DealDRAFT_0950	5.181e-60	213.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,42JYY@68298|Syntrophomonadaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158397_k127_408804_7	227377.CBU_2082	2.878e-13	77.0	COG3698@1|root,COG3698@2|Bacteria,1NM1P@1224|Proteobacteria,1SI38@1236|Gammaproteobacteria,1JD4Z@118969|Legionellales	118969|Legionellales	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
SRR25158397_k127_4089945_4	1124780.ANNU01000052_gene3550	1.583e-24	106.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_4089945_0	913325.N799_01140	2.469e-274	861.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1X4B6@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidase	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158397_k127_4089945_5	1237149.C900_03408	3.405e-07	61.0	COG2755@1|root,COG3209@1|root,COG4733@1|root,COG2755@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,4NJGD@976|Bacteroidetes,47VZA@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158397_k127_4089945_2	1267533.KB906737_gene1596	2.743e-42	161.0	COG2318@1|root,COG2318@2|Bacteria,3Y5FN@57723|Acidobacteria,2JJTU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158397_k127_4089945_1	1121899.Q764_05110	3.506e-43	167.0	COG3324@1|root,COG3324@2|Bacteria,4PKMI@976|Bacteroidetes,1IJX9@117743|Flavobacteriia,2NWMC@237|Flavobacterium	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_4089945_3	42256.RradSPS_2282	3.355e-31	126.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_410758_1	215803.DB30_0258	8.054e-94	317.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YWSA@29|Myxococcales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158397_k127_410758_2	671143.DAMO_0325	1.824e-72	254.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
SRR25158397_k127_410758_3	1408424.JHYI01000016_gene2560	1.91e-38	154.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158397_k127_410758_0	861299.J421_2451	5.717e-153	501.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158397_k127_410758_4	1242864.D187_007993	1.632e-17	83.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRR25158397_k127_4119580_3	1192034.CAP_6443	2.42e-25	109.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,42VE0@68525|delta/epsilon subdivisions,2WSAE@28221|Deltaproteobacteria,2YV27@29|Myxococcales	28221|Deltaproteobacteria	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N,T6SS_VasJ
SRR25158397_k127_4119580_0	985867.AEWF01000001_gene2088	9.12e-142	498.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2TSY0@28211|Alphaproteobacteria,47F0D@766|Rickettsiales	766|Rickettsiales	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
SRR25158397_k127_4119580_2	381666.H16_B2417	4.675e-31	132.0	COG3455@1|root,COG3455@2|Bacteria,1N723@1224|Proteobacteria,2VWJC@28216|Betaproteobacteria,1K6TX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Type VI secretion system protein DotU	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
SRR25158397_k127_4119580_1	1192034.CAP_6440	1.734e-48	183.0	COG3522@1|root,COG3522@2|Bacteria,1RD5T@1224|Proteobacteria,43F3D@68525|delta/epsilon subdivisions,2X38C@28221|Deltaproteobacteria,2YUTK@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
SRR25158397_k127_4131590_4	1123229.AUBC01000041_gene3810	2.129e-21	98.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2UC9T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	B	PFAM SWIB MDM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
SRR25158397_k127_4131590_0	1232410.KI421416_gene2699	5.293e-188	601.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2WJJP@28221|Deltaproteobacteria,43UUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sulfate permease family	ychM	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,STAS,STAS_2,Sulfate_transp
SRR25158397_k127_4131590_5	1123504.JQKD01000027_gene4143	5.462e-12	75.0	COG0810@1|root,COG0810@2|Bacteria,1PWFZ@1224|Proteobacteria,2WC0I@28216|Betaproteobacteria,4AINM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158397_k127_4131590_1	1242864.D187_002839	4.419e-139	469.0	COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria	1224|Proteobacteria	E	Zinc metalloprotease (Elastase)	-	-	3.4.24.25,3.4.24.28	ko:K01400,ko:K08604	ko05110,ko05111,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PPC,Peptidase_M4,Peptidase_M4_C
SRR25158397_k127_4131590_2	278963.ATWD01000001_gene2963	1.45e-95	327.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158397_k127_4131590_3	1343740.M271_35755	2.467e-48	186.0	2DP7T@1|root,330W7@2|Bacteria,2IH3C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4135366_4	1267535.KB906767_gene2339	5.328e-28	117.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria,2JNEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
SRR25158397_k127_4135366_2	56780.SYN_02636	1.041e-65	233.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158397_k127_4135366_1	649747.HMPREF0083_03747	2.296e-79	277.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,26SQU@186822|Paenibacillaceae	91061|Bacilli	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158397_k127_4135366_3	1121430.JMLG01000012_gene2024	3.44e-42	168.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,2625H@186807|Peptococcaceae	186801|Clostridia	GM	pfam php	ywqE	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158397_k127_4135366_5	765911.Thivi_0431	1.273e-26	114.0	2C945@1|root,32W5M@2|Bacteria,1RFGX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
SRR25158397_k127_4135366_0	1047013.AQSP01000112_gene392	8.976e-91	326.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SRR25158397_k127_4135366_7	521045.Kole_0012	2.371e-16	89.0	COG1596@1|root,COG1596@2|Bacteria,2GCU6@200918|Thermotogae	200918|Thermotogae	M	polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158397_k127_4135366_8	1122613.ATUP01000001_gene1680	4.496e-05	55.0	COG5338@1|root,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria,2U090@28211|Alphaproteobacteria,43ZQX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
SRR25158397_k127_4135366_6	2340.JV46_20030	6.295e-25	120.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,1J709@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158397_k127_4136719_0	234267.Acid_7035	0.0	1098.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158397_k127_4136719_3	1384056.N787_06540	4.577e-75	285.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,1S9I9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158397_k127_4136719_1	1384056.N787_06545	2.684e-95	344.0	2D125@1|root,32T9R@2|Bacteria,1N30F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4136719_4	768671.ThimaDRAFT_2804	4.919e-63	235.0	COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,1SG1X@1236|Gammaproteobacteria,1WZ0T@135613|Chromatiales	135613|Chromatiales	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
SRR25158397_k127_4136719_2	861299.J421_5806	4.465e-89	319.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GUN4,GUN4_N,Peptidase_C13,Peptidase_C14,TPR_10
SRR25158397_k127_4136719_5	395495.Lcho_4095	4.031e-34	151.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2WHQF@28216|Betaproteobacteria,1KM9W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158397_k127_413714_1	243231.GSU1475	7.334e-45	172.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158397_k127_413714_0	243231.GSU2195	1.629e-165	528.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,43TA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158397_k127_4141402_1	1379698.RBG1_1C00001G1351	2.188e-114	380.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158397_k127_4141402_2	861299.J421_3685	3.76e-63	222.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158397_k127_4141402_6	862908.BMS_3186	5.215e-13	74.0	2EC0X@1|root,33605@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4141402_4	1094715.CM001375_gene162	8.337e-50	199.0	COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,1S6C2@1236|Gammaproteobacteria,1JDRS@118969|Legionellales	118969|Legionellales	S	Putative esterase	besA	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158397_k127_4141402_0	1242864.D187_001103	7.888e-148	487.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria,2YUG1@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
SRR25158397_k127_4141402_5	314230.DSM3645_01776	1.142e-13	80.0	2EEQZ@1|root,338IP@2|Bacteria,2J15B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4141402_3	1267535.KB906767_gene1129	2.234e-60	219.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_4141402_7	1042876.PPS_4905	2.247e-07	53.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1YXTR@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
SRR25158397_k127_4152021_4	414684.RC1_3281	2.152e-62	237.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,2TR3E@28211|Alphaproteobacteria,2JUCS@204441|Rhodospirillales	204441|Rhodospirillales	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4152021_2	204669.Acid345_0817	2.992e-92	316.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_4152021_7	290397.Adeh_0475	3.428e-19	91.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158397_k127_4152021_9	545694.TREPR_0168	1.347e-09	70.0	COG1032@1|root,COG1032@2|Bacteria,2JADG@203691|Spirochaetes	203691|Spirochaetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4152021_0	562970.Btus_1136	2.876e-215	702.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,4HVCC@91061|Bacilli,279N4@186823|Alicyclobacillaceae	1239|Firmicutes	CK	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
SRR25158397_k127_4152021_3	479434.Sthe_0155	3.727e-77	284.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_4152021_1	525904.Tter_2549	2.063e-127	424.0	COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria	2|Bacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
SRR25158397_k127_4152021_8	1089550.ATTH01000001_gene149	3.421e-16	88.0	COG2353@1|root,COG2353@2|Bacteria,4PBAH@976|Bacteroidetes,1FK7G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158397_k127_4152021_6	518766.Rmar_0432	4.352e-26	119.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1FK9R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158397_k127_4152021_5	1089550.ATTH01000001_gene148	6.503e-53	203.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4165112_1	497964.CfE428DRAFT_0941	6.439e-46	170.0	COG0726@1|root,COG0726@2|Bacteria,46T5N@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158397_k127_4165112_0	497964.CfE428DRAFT_0931	4.166e-48	185.0	COG2230@1|root,COG2230@2|Bacteria,46Z8K@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4165112_3	103690.17134448	3.286e-18	90.0	COG0642@1|root,COG0745@1|root,COG4252@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG4252@2|Bacteria,1G3JA@1117|Cyanobacteria,1HJCM@1161|Nostocales	1117|Cyanobacteria	T	Integral membrane sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,Response_reg
SRR25158397_k127_4165112_2	671143.DAMO_0253	3.706e-24	114.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
SRR25158397_k127_4165112_5	235985.BBPN01000011_gene4187	1.317e-08	67.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
SRR25158397_k127_4165112_4	68170.KL590484_gene7713	6.661e-18	96.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4DYXX@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	wbbL	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	iNJ661.Rv3265c	Glyco_tranf_2_3,Glycos_transf_2
SRR25158397_k127_4165112_6	398578.Daci_1314	0.0001427	48.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2VHMP@28216|Betaproteobacteria,4ABUQ@80864|Comamonadaceae	28216|Betaproteobacteria	GM	PFAM ABC transporter related	wzt	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158397_k127_4168704_8	1278073.MYSTI_07079	6.051e-09	69.0	2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4168704_4	192952.MM_1134	2.501e-83	296.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,2N966@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158397_k127_4168704_7	237368.SCABRO_02716	6.189e-29	124.0	COG1208@1|root,COG1208@2|Bacteria,2J0B4@203682|Planctomycetes	203682|Planctomycetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR25158397_k127_4168704_5	1034943.BN1094_01884	6.506e-71	248.0	COG0463@1|root,COG0463@2|Bacteria,1PBWN@1224|Proteobacteria,1SWNE@1236|Gammaproteobacteria,1JFW2@118969|Legionellales	118969|Legionellales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_4168704_6	1192034.CAP_7932	1.176e-41	164.0	COG0463@1|root,COG2227@1|root,COG0463@2|Bacteria,COG2227@2|Bacteria,1R0Z5@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_4168704_1	70601.3256828	3.445e-111	377.0	COG1232@1|root,arCOG01522@2157|Archaea,2XY37@28890|Euryarchaeota	28890|Euryarchaeota	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158397_k127_4168704_2	1047013.AQSP01000116_gene1112	8.275e-99	344.0	COG2605@1|root,COG2605@2|Bacteria,2NP6Q@2323|unclassified Bacteria	2|Bacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158397_k127_4168704_3	1408164.MOLA814_00702	2.172e-84	290.0	COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158397_k127_4168704_0	929562.Emtol_1919	6.588e-114	376.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,47JIX@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRR25158397_k127_4168704_9	595536.ADVE02000001_gene2217	4.575e-08	65.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,2U1FH@28211|Alphaproteobacteria,36ZEE@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_4175719_13	234267.Acid_4496	5.173e-31	138.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158397_k127_4175719_8	670487.Ocepr_1224	7.436e-82	281.0	COG1013@1|root,COG1013@2|Bacteria,1WIGM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158397_k127_4175719_3	670487.Ocepr_1225	5.285e-152	499.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1WIAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
SRR25158397_k127_4175719_14	29581.BW37_03330	1.555e-20	100.0	2EBMP@1|root,335MW@2|Bacteria,1NAJH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4175719_1	404589.Anae109_2250	6.148e-187	605.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158397_k127_4175719_10	404589.Anae109_2248	3.426e-56	205.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1N3ZM@1224|Proteobacteria,42TUU@68525|delta/epsilon subdivisions,2WQ8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KP	PFAM iron dependent repressor	ideR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
SRR25158397_k127_4175719_18	926560.KE387023_gene1235	0.0002477	48.0	COG3895@1|root,COG4249@1|root,COG3895@2|Bacteria,COG4249@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
SRR25158397_k127_4175719_12	379066.GAU_3293	7.204e-34	138.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
SRR25158397_k127_4175719_2	485913.Krac_4279	4.252e-169	557.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2G8BR@200795|Chloroflexi	200795|Chloroflexi	IQ	TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158397_k127_4175719_4	1449126.JQKL01000006_gene759	2.619e-149	482.0	COG0535@1|root,COG0535@2|Bacteria,1TR85@1239|Firmicutes,249NQ@186801|Clostridia,26AE6@186813|unclassified Clostridiales	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_4175719_6	1403819.BATR01000127_gene4529	1.629e-131	430.0	COG1522@1|root,COG1522@2|Bacteria,46SDK@74201|Verrucomicrobia,2IU3G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4175719_7	1295642.H839_02886	3.99e-110	387.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1WEVQ@129337|Geobacillus	91061|Bacilli	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158397_k127_4175719_0	204669.Acid345_2713	4.969e-206	658.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
SRR25158397_k127_4175719_5	316067.Geob_1014	2.388e-136	450.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria,43U0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SRR25158397_k127_4175719_9	1267535.KB906767_gene5535	7.134e-65	247.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
SRR25158397_k127_4175719_16	1345697.M493_16915	2.373e-09	72.0	COG5652@1|root,COG5652@2|Bacteria,1TU2J@1239|Firmicutes,4HQ9P@91061|Bacilli,1WGH9@129337|Geobacillus	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158397_k127_4182053_1	1304880.JAGB01000004_gene1468	2.234e-101	340.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia	186801|Clostridia	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SRR25158397_k127_4182053_2	562970.Btus_0564	7.356e-82	286.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,278SX@186823|Alicyclobacillaceae	91061|Bacilli	G	Amidohydrolase family	-	-	3.5.1.25	ko:K01443,ko:K16786,ko:K16787	ko00520,ko01130,ko02010,map00520,map01130,map02010	M00582	R02059	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Amidohydro_1
SRR25158397_k127_4182053_3	1160707.AJIK01000010_gene2488	5.92e-66	233.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,26F6G@186818|Planococcaceae	91061|Bacilli	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	iYO844.BSU35020	Glucosamine_iso
SRR25158397_k127_4182053_6	928724.SacglDRAFT_03544	2.403e-21	104.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158397_k127_4182053_0	365046.Rta_16960	3.815e-115	397.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158397_k127_4182053_4	446468.Ndas_3615	3.355e-28	132.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4EFMK@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158397_k127_4182053_5	204669.Acid345_4183	7.925e-26	108.0	COG1278@1|root,COG1278@2|Bacteria,3Y5GC@57723|Acidobacteria,2JK23@204432|Acidobacteriia	204432|Acidobacteriia	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158397_k127_418997_1	1408424.JHYI01000012_gene2210	2.306e-119	393.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,1ZAZB@1386|Bacillus	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158397_k127_418997_3	1218075.BAYA01000034_gene6157	1.094e-62	236.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,2W05B@28216|Betaproteobacteria,1KGU5@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158397_k127_418997_5	1003200.AXXA_08418	2.994e-10	67.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,3T4IF@506|Alcaligenaceae	28216|Betaproteobacteria	P	Rhodanese-related sulfurtransferase	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_418997_2	1499967.BAYZ01000095_gene4228	1.057e-74	257.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158397_k127_418997_0	330214.NIDE3178	3.404e-167	539.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158397_k127_418997_4	1382359.JIAL01000001_gene1199	2.085e-56	225.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
SRR25158397_k127_419038_3	316274.Haur_4216	2.455e-55	213.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158397_k127_419038_2	1267534.KB906754_gene2572	2.675e-117	402.0	COG1473@1|root,COG1473@2|Bacteria,3Y40E@57723|Acidobacteria,2JIBT@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158397_k127_419038_9	1340493.JNIF01000003_gene4149	1.201e-05	56.0	COG3386@1|root,COG4625@1|root,COG3386@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
SRR25158397_k127_419038_7	562970.Btus_3146	5.857e-12	70.0	COG4625@1|root,COG5492@1|root,COG4625@2|Bacteria,COG5492@2|Bacteria,1V72Z@1239|Firmicutes	1239|Firmicutes	N	PFAM S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
SRR25158397_k127_419038_0	1254432.SCE1572_41890	4.597e-236	749.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158397_k127_419038_1	391038.Bphy_0391	1.782e-173	586.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_419038_5	986075.CathTA2_0458	8.432e-14	80.0	COG0745@1|root,COG0745@2|Bacteria,1TTB8@1239|Firmicutes,4HAJK@91061|Bacilli	91061|Bacilli	T	Transcriptional regulator	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_419038_6	1317122.ATO12_10930	1.608e-12	74.0	COG0745@1|root,COG0745@2|Bacteria,4NP5C@976|Bacteroidetes,1I24M@117743|Flavobacteriia,2YJR0@290174|Aquimarina	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_419038_4	553178.CAPGI0001_0607	5.943e-54	203.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia,1EQ16@1016|Capnocytophaga	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
SRR25158397_k127_419038_8	700598.Niako_0071	1.062e-07	65.0	COG3568@1|root,COG3568@2|Bacteria,4NHRK@976|Bacteroidetes,1IPHW@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,VCBS
SRR25158397_k127_419038_10	1463853.JOHW01000011_gene3600	2.038e-05	50.0	COG4995@1|root,COG4995@2|Bacteria,2GM3Q@201174|Actinobacteria	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10
SRR25158397_k127_419038_11	1306174.JODP01000025_gene4147	8.11e-05	55.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,Trans_reg_C
SRR25158397_k127_419038_12	1214242.B446_04195	0.0001347	51.0	COG1191@1|root,COG1191@2|Bacteria,2GMMN@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158397_k127_4201017_6	1144275.COCOR_07749	1.304e-54	201.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria	1224|Proteobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158397_k127_4201017_7	42256.RradSPS_2982	1.109e-46	173.0	COG2105@1|root,COG2105@2|Bacteria,2GV2B@201174|Actinobacteria	201174|Actinobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158397_k127_4201017_8	420662.Mpe_A0045	2.711e-27	128.0	COG2940@1|root,COG2940@2|Bacteria,1RIQT@1224|Proteobacteria,2VT7F@28216|Betaproteobacteria,1KM5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158397_k127_4201017_1	1183438.GKIL_3588	3.725e-128	425.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	pgcp	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158397_k127_4201017_0	1379698.RBG1_1C00001G0471	1.836e-221	696.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_4201017_9	1499967.BAYZ01000158_gene436	2.232e-25	114.0	COG1664@1|root,COG1664@2|Bacteria,2NQ1N@2323|unclassified Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158397_k127_4201017_12	234267.Acid_1509	3.224e-05	56.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4201017_3	443143.GM18_2043	5.343e-92	317.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158397_k127_4201017_4	645991.Sgly_1639	4.952e-88	299.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,261I1@186807|Peptococcaceae	186801|Clostridia	P	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_4201017_10	146922.JOFU01000044_gene5521	6.387e-21	108.0	COG3227@1|root,COG3227@2|Bacteria,2GJEW@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase M4	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M4,Peptidase_M4_C
SRR25158397_k127_4201017_2	247490.KSU1_C0701	6.56e-106	370.0	COG0577@1|root,COG0577@2|Bacteria,2IY2P@203682|Planctomycetes	203682|Planctomycetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX,MacB_PCD
SRR25158397_k127_4201017_5	1121920.AUAU01000012_gene2631	2.668e-67	259.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_4201017_11	1096546.WYO_0651	1.965e-15	89.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_4209500_4	134676.ACPL_3232	3.935e-14	82.0	2DC71@1|root,32TZ3@2|Bacteria,2H338@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4209500_3	313606.M23134_06285	3.939e-17	90.0	2EBPK@1|root,335PP@2|Bacteria,4NWAZ@976|Bacteroidetes,47W5A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4209500_1	929712.KI912613_gene4201	5.374e-87	304.0	COG0438@1|root,COG0438@2|Bacteria,2GMR9@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4209500_5	1120936.KB907208_gene567	1.816e-08	66.0	2FDZQ@1|root,345ZY@2|Bacteria,2H799@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4209500_2	349521.HCH_00082	8.389e-18	95.0	2DRBC@1|root,33B2X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4209500_0	929712.KI912613_gene4204	4.445e-133	434.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4218097_10	1249627.D779_0011	8.95e-37	151.0	COG2120@1|root,COG2120@2|Bacteria,1MUTM@1224|Proteobacteria,1S2K7@1236|Gammaproteobacteria,1X08V@135613|Chromatiales	135613|Chromatiales	M	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PIG-L
SRR25158397_k127_4218097_9	543632.JOJL01000037_gene6390	2.119e-40	164.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,2IA4H@201174|Actinobacteria,4D9U5@85008|Micromonosporales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HAMP
SRR25158397_k127_4218097_7	866895.HBHAL_4003	1.511e-52	194.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3NDRC@45667|Halobacillus	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158397_k127_4218097_15	682795.AciX8_2392	5.335e-22	99.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria,2JJVA@204432|Acidobacteriia	204432|Acidobacteriia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158397_k127_4218097_4	301.JNHE01000001_gene556	7.019e-58	207.0	COG2227@1|root,COG2227@2|Bacteria,1REWV@1224|Proteobacteria,1T1J3@1236|Gammaproteobacteria,1YFX9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Methyltransferase domain	ubiG3	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158397_k127_4218097_0	204669.Acid345_0153	6.21e-169	547.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158397_k127_4218097_16	694431.DESACE_02120	8.852e-17	95.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2M773@213113|Desulfurellales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158397_k127_4218097_3	378806.STAUR_1517	1.802e-58	217.0	COG1028@1|root,COG1028@2|Bacteria,1RA3U@1224|Proteobacteria,42TV0@68525|delta/epsilon subdivisions,2WR1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158397_k127_4218097_13	517417.Cpar_0360	9.277e-29	122.0	COG2318@1|root,COG2318@2|Bacteria,1FF75@1090|Chlorobi	1090|Chlorobi	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158397_k127_4218097_11	1329516.JPST01000013_gene349	2.712e-29	137.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27BIU@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_4218097_8	518766.Rmar_0192	3.777e-46	169.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158397_k127_4218097_12	1191523.MROS_0679	5.97e-29	121.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158397_k127_4218097_6	1116472.MGMO_153c00120	1.463e-53	194.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,1XEUU@135618|Methylococcales	135618|Methylococcales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158397_k127_4218097_17	247490.KSU1_C0406	2.113e-14	83.0	COG1254@1|root,COG1254@2|Bacteria,2J4P5@203682|Planctomycetes	203682|Planctomycetes	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
SRR25158397_k127_4218097_2	243231.GSU1524	1.07e-60	217.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,43TVI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158397_k127_4218097_1	648996.Theam_1712	2.542e-75	263.0	COG0496@1|root,COG0496@2|Bacteria,2G3WU@200783|Aquificae	200783|Aquificae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158397_k127_4218097_14	1278073.MYSTI_06534	1.02e-28	128.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_4218097_5	345341.KUTG_00971	3.724e-54	196.0	COG1995@1|root,COG1995@2|Bacteria,2GRPG@201174|Actinobacteria,4E32U@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158397_k127_4229191_2	1385517.N800_06205	7.885e-62	224.0	COG0500@1|root,COG0500@2|Bacteria,1R947@1224|Proteobacteria,1SUF1@1236|Gammaproteobacteria,1X4RG@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158397_k127_4229191_4	1123252.ATZF01000001_gene1011	2.915e-05	56.0	2DRFR@1|root,33BIP@2|Bacteria,1UBQS@1239|Firmicutes,4IN5S@91061|Bacilli,27CBE@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	DUF454,PGPGW
SRR25158397_k127_4229191_1	794903.OPIT5_28655	2.498e-77	269.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,46T5T@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
SRR25158397_k127_4229191_3	1254432.SCE1572_07150	2.03e-05	55.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SRR25158397_k127_4229191_0	1121013.P873_00385	1.293e-173	556.0	COG0464@1|root,COG0464@2|Bacteria,1RCHW@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158397_k127_4241501_3	1121015.N789_06010	2.373e-30	128.0	COG4627@1|root,COG4627@2|Bacteria,1NKXY@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158397_k127_4241501_2	1283300.ATXB01000001_gene2332	2.909e-34	146.0	COG2227@1|root,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria	1224|Proteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Methyltransf_23
SRR25158397_k127_4241501_1	1157634.KB912987_gene3652	1.599e-36	153.0	COG0535@1|root,COG0535@2|Bacteria,2H1J8@201174|Actinobacteria	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158397_k127_4241501_4	351016.RAZWK3B_00900	3.778e-23	111.0	COG0438@1|root,COG0438@2|Bacteria,1RAXB@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158397_k127_4241501_0	261292.Nit79A3_0433	1.875e-55	206.0	COG2227@1|root,COG2227@2|Bacteria,1RAW1@1224|Proteobacteria,2WB3M@28216|Betaproteobacteria,37289@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SRR25158397_k127_4241501_6	1144275.COCOR_07436	3.777e-11	68.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria	1224|Proteobacteria	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158397_k127_4241501_5	215803.DB30_0658	1.199e-11	68.0	2DBN3@1|root,2ZA1Q@2|Bacteria,1PXHC@1224|Proteobacteria,438NW@68525|delta/epsilon subdivisions,2X3WR@28221|Deltaproteobacteria,2YXD5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_425621_3	580332.Slit_2908	1.557e-30	124.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,2W39J@28216|Betaproteobacteria,44WJC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158397_k127_425621_0	247633.GP2143_10457	2.839e-87	304.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_425621_1	204669.Acid345_3562	3.938e-78	287.0	COG1044@1|root,COG1044@2|Bacteria,3Y2ZS@57723|Acidobacteria,2JIC3@204432|Acidobacteriia	204432|Acidobacteriia	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
SRR25158397_k127_425621_2	240015.ACP_2769	4.091e-72	270.0	COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria,2JIR4@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_425621_4	1121451.DESAM_10192	3.02e-12	79.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2M7XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158397_k127_4264706_3	59538.XP_005975276.1	1.27e-55	206.0	COG0265@1|root,KOG1320@2759|Eukaryota,38G0B@33154|Opisthokonta,3BA39@33208|Metazoa,3CU4J@33213|Bilateria,486Q8@7711|Chordata,4925G@7742|Vertebrata,3J5BW@40674|Mammalia,4IZHF@91561|Cetartiodactyla	33208|Metazoa	O	protease	-	-	3.4.21.107,3.4.21.108	ko:K04771,ko:K08669	ko01503,ko02020,ko04210,ko04214,ko04215,ko05012,map01503,map02020,map04210,map04214,map04215,map05012	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158397_k127_4264706_2	1254432.SCE1572_27920	2.448e-70	256.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42T6B@68525|delta/epsilon subdivisions,2WPVS@28221|Deltaproteobacteria,2YWZ0@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158397_k127_4264706_1	1267535.KB906767_gene1409	3.56e-72	268.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria,2JHNA@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158397_k127_4264706_5	880073.Calab_1754	5.557e-40	173.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
SRR25158397_k127_4264706_6	1121344.JHZO01000004_gene1467	3.268e-37	153.0	COG4112@1|root,COG4112@2|Bacteria,1V277@1239|Firmicutes,252TJ@186801|Clostridia	186801|Clostridia	S	phosphoesterase (MutT family)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4264706_0	994479.GL877883_gene7292	1.786e-81	288.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DY3G@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158397_k127_4264706_4	1379270.AUXF01000002_gene1310	4.26e-41	155.0	2CHCP@1|root,32S5R@2|Bacteria,1ZV1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158397_k127_4269188_7	71139.XP_010025117.1	1.155e-06	60.0	COG0169@1|root,KOG0692@2759|Eukaryota,37I1M@33090|Viridiplantae,3GDN1@35493|Streptophyta	35493|Streptophyta	E	Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SRR25158397_k127_4269188_1	502025.Hoch_5388	1.059e-34	143.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,43824@68525|delta/epsilon subdivisions,2X3C7@28221|Deltaproteobacteria,2YVD2@29|Myxococcales	28221|Deltaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158397_k127_4269188_2	204669.Acid345_1193	2.183e-32	135.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria,2JJ0T@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158397_k127_4269188_3	1499967.BAYZ01000096_gene4319	4.836e-28	117.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158397_k127_4269188_4	631362.Thi970DRAFT_00649	1.96e-14	85.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158397_k127_4269188_5	316274.Haur_1576	2.795e-10	73.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158397_k127_4269188_0	998674.ATTE01000001_gene987	8.08e-37	153.0	2DBAY@1|root,2Z84S@2|Bacteria,1R7V4@1224|Proteobacteria,1S1T1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
SRR25158397_k127_4269188_6	1121878.AUGL01000014_gene1695	2.409e-09	68.0	COG0308@1|root,COG0823@1|root,COG0308@2|Bacteria,COG0823@2|Bacteria,1R8QH@1224|Proteobacteria,1RN7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EU	COG0823 Periplasmic component of the Tol biopolymer transport system	VVA0929	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158397_k127_4271374_9	379066.GAU_0656	4.626e-05	46.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Beta-eliminating lyase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158397_k127_4271374_4	639030.JHVA01000001_gene3108	9.785e-54	196.0	COG5553@1|root,COG5553@2|Bacteria,3Y975@57723|Acidobacteria,2JNQM@204432|Acidobacteriia	204432|Acidobacteriia	S	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
SRR25158397_k127_4271374_2	240015.ACP_2260	1.103e-149	484.0	COG0104@1|root,COG0104@2|Bacteria,3Y2Z9@57723|Acidobacteria,2JIIV@204432|Acidobacteriia	204432|Acidobacteriia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158397_k127_4271374_0	1237149.C900_00889	1.51e-197	639.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158397_k127_4271374_1	204669.Acid345_1052	4.404e-164	545.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158397_k127_4271374_7	1121898.Q766_15010	2.954e-19	100.0	2E47A@1|root,32Z36@2|Bacteria,4NWDV@976|Bacteroidetes,1IDBK@117743|Flavobacteriia,2NXYD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4271374_3	1385517.N800_09760	3.602e-110	384.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_4271374_5	1040989.AWZU01000080_gene5013	1.222e-43	167.0	28P93@1|root,2ZC2V@2|Bacteria,1RAKY@1224|Proteobacteria,2U7VG@28211|Alphaproteobacteria,3JYVY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158397_k127_4271374_6	1146883.BLASA_1268	4.716e-27	118.0	2AU91@1|root,31JWC@2|Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRR25158397_k127_4271374_8	1267535.KB906767_gene1183	1.943e-16	79.0	COG0451@1|root,COG0451@2|Bacteria,3Y3T4@57723|Acidobacteria,2JIDC@204432|Acidobacteriia	204432|Acidobacteriia	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158397_k127_4272247_0	234831.PSM_A3090	0.0	1152.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,1RP38@1236|Gammaproteobacteria,2Q0BE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158397_k127_4272247_1	1519464.HY22_10730	4.891e-99	337.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_4290350_4	876269.ARWA01000001_gene2747	1.359e-58	205.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,3N9YR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158397_k127_4290350_11	994479.GL877878_gene871	3.009e-07	57.0	COG1846@1|root,COG1846@2|Bacteria,2II5E@201174|Actinobacteria,4E7EG@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158397_k127_4290350_10	109760.SPPG_02150T0	1.173e-08	68.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta	33154|Opisthokonta	M	Protein notum homolog	-	-	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
SRR25158397_k127_4290350_5	927677.ALVU02000001_gene4167	2.979e-37	157.0	COG2199@1|root,COG3706@2|Bacteria,1GBM2@1117|Cyanobacteria	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
SRR25158397_k127_4290350_6	768679.TTX_0788	1.375e-33	147.0	COG2379@1|root,arCOG04170@2157|Archaea,2XPZD@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM MOFRL domain protein	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158397_k127_4290350_3	1267535.KB906767_gene3597	9.547e-71	276.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SRR25158397_k127_4290350_8	1470591.BW41_03361	4.289e-25	117.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2U9EX@28211|Alphaproteobacteria,2K64Z@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158397_k127_4290350_1	1382359.JIAL01000001_gene1578	1.025e-91	308.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158397_k127_4290350_0	1111479.AXAR01000003_gene1587	1.74e-130	431.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HBS0@91061|Bacilli,279F0@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158397_k127_4290350_7	671143.DAMO_2903	1.593e-25	122.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
SRR25158397_k127_4290350_2	857087.Metme_0581	9.77e-86	294.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria,1XENI@135618|Methylococcales	135618|Methylococcales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4293793_7	1117314.PCIT_00308	1.149e-20	102.0	2C6NZ@1|root,335K8@2|Bacteria,1N2AP@1224|Proteobacteria,1SFT8@1236|Gammaproteobacteria,2Q4N6@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
SRR25158397_k127_4293793_6	234267.Acid_4874	1.317e-23	104.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4293793_0	305700.B447_02231	1.554e-93	311.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VIV6@28216|Betaproteobacteria,2KUJX@206389|Rhodocyclales	206389|Rhodocyclales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4293793_3	748247.AZKH_3472	1.399e-71	261.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2VIZI@28216|Betaproteobacteria,2KUZ6@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158397_k127_4293793_1	1121377.KB906409_gene861	1.097e-92	310.0	COG3662@1|root,COG3662@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158397_k127_4293793_2	204669.Acid345_3487	3.024e-81	291.0	COG3279@1|root,COG3279@2|Bacteria,3Y3B3@57723|Acidobacteria,2JP1W@204432|Acidobacteriia	204432|Acidobacteriia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_4293793_4	204669.Acid345_3488	1.114e-64	233.0	COG2972@1|root,COG2972@2|Bacteria,3Y4BE@57723|Acidobacteria,2JMFY@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_4293793_5	1502852.FG94_03180	4.243e-39	158.0	COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4293793_8	1502852.FG94_03179	6.279e-09	61.0	29KMV@1|root,307J5@2|Bacteria,1PX4Q@1224|Proteobacteria,2WCMS@28216|Betaproteobacteria,477X5@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4302599_8	313612.L8106_16329	3.577e-05	55.0	COG3184@1|root,COG3184@2|Bacteria,1G97G@1117|Cyanobacteria,1HD1C@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
SRR25158397_k127_4302599_1	1245469.S58_36280	1.022e-165	536.0	2EPJD@1|root,33H61@2|Bacteria,1P9VX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4302599_7	909613.UO65_5584	8.665e-08	66.0	COG2374@1|root,COG4625@1|root,COG4733@1|root,COG5492@1|root,COG2374@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
SRR25158397_k127_4302599_3	391625.PPSIR1_11570	4.709e-39	163.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
SRR25158397_k127_4302599_4	1184609.KILIM_016_00730	1.062e-34	137.0	COG4753@1|root,COG4753@2|Bacteria,2I2VC@201174|Actinobacteria,4F7Z8@85018|Dermatophilaceae	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4302599_5	880073.Calab_3013	3.072e-16	90.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
SRR25158397_k127_4302599_0	204669.Acid345_0175	1.299e-252	800.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158397_k127_4302599_9	638303.Thal_0517	0.000224	48.0	2E20Q@1|root,32X8P@2|Bacteria,2G53C@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4302599_6	589865.DaAHT2_0189	7.21e-14	85.0	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,43D5Q@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
SRR25158397_k127_4302599_2	234267.Acid_5283	2.497e-77	273.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158397_k127_4304090_7	938289.CAJN020000003_gene910	3.65e-31	132.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,2686P@186813|unclassified Clostridiales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158397_k127_4304090_3	926550.CLDAP_25100	1.566e-84	286.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158397_k127_4304090_2	234267.Acid_0734	1.277e-123	406.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158397_k127_4304090_0	330214.NIDE1728	1.118e-229	726.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158397_k127_4304090_6	562743.JH976437_gene2276	1.924e-35	142.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158397_k127_4304090_5	1144275.COCOR_07305	4.261e-74	262.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158397_k127_4304090_9	1125863.JAFN01000001_gene1525	3.847e-05	54.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158397_k127_4304090_4	1123073.KB899244_gene350	6.436e-83	284.0	COG0491@1|root,COG0491@2|Bacteria,1QBJF@1224|Proteobacteria,1T752@1236|Gammaproteobacteria,1X8SQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158397_k127_4304090_1	1121472.AQWN01000002_gene2280	7.972e-190	613.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,260BN@186807|Peptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158397_k127_4305336_14	326297.Sama_3330	1.547e-32	131.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,1RY74@1236|Gammaproteobacteria,2Q9QH@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4305336_0	1254432.SCE1572_15985	6.772e-193	628.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_4305336_6	1278073.MYSTI_06593	1.532e-121	410.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,437YB@68525|delta/epsilon subdivisions,2X387@28221|Deltaproteobacteria,2YVXR@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_4305336_13	1267534.KB906754_gene2561	2.965e-40	169.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	2.3.1.82	ko:K03830,ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158397_k127_4305336_5	234267.Acid_1794	4.03e-129	433.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158397_k127_4305336_9	56110.Oscil6304_0566	3.092e-81	292.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_4305336_12	867903.ThesuDRAFT_02355	2.549e-66	245.0	COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158397_k127_4305336_17	1121271.AUCM01000013_gene2836	0.0001122	54.0	2EHWT@1|root,33BNE@2|Bacteria,1NGY3@1224|Proteobacteria,2UHQC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4305336_3	251221.35211765	1.833e-169	561.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_4305336_1	234267.Acid_4168	6.125e-176	565.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_4305336_8	234267.Acid_4169	4.792e-114	381.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158397_k127_4305336_16	1233951.IO90_18880	2.581e-06	61.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Colicin-DNase,Gp58,Laminin_G_3,Pec_lyase,Pec_lyase_C,Pectinesterase,Prophage_tail,WHH,fn3
SRR25158397_k127_4305336_2	204669.Acid345_0197	1.562e-170	558.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4305336_4	1144275.COCOR_00357	1.71e-151	505.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2YUN4@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg,RsbRD_N,SBP_bac_3
SRR25158397_k127_4305336_10	861299.J421_1374	3.565e-81	293.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd2	-	1.4.1.1,1.5.1.25,4.3.1.12	ko:K01750,ko:K18258,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000,ko04147	-	-	-	OCD_Mu_crystall
SRR25158397_k127_4305336_11	935557.ATYB01000009_gene596	5.274e-74	261.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158397_k127_4305336_15	234267.Acid_6891	1.773e-08	60.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
SRR25158397_k127_4305336_7	1121920.AUAU01000015_gene1159	2.672e-118	390.0	COG2059@1|root,COG2059@2|Bacteria,3Y572@57723|Acidobacteria	57723|Acidobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158397_k127_4312671_3	652103.Rpdx1_4494	1.728e-24	108.0	COG2161@1|root,COG2161@2|Bacteria,1NBSZ@1224|Proteobacteria,2UD9I@28211|Alphaproteobacteria,3K1Y8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158397_k127_4312671_6	107635.AZUO01000001_gene2473	9.923e-07	55.0	COG1487@1|root,COG1487@2|Bacteria,1RD5N@1224|Proteobacteria,2U73N@28211|Alphaproteobacteria,36ZYM@31993|Methylocystaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158397_k127_4312671_4	652103.Rpdx1_4495	1.726e-18	86.0	COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,2U73E@28211|Alphaproteobacteria,3K6JX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158397_k127_4312671_1	693977.Deipr_1257	2.355e-48	185.0	COG1409@1|root,COG1409@2|Bacteria,1WM9G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4312671_2	945713.IALB_2163	8.563e-38	159.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158397_k127_4312671_5	246197.MXAN_0076	7.163e-13	82.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	tfaE	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Caudo_TAP,Macro
SRR25158397_k127_4312671_0	290318.Cvib_1478	6.887e-189	602.0	COG0493@1|root,COG0493@2|Bacteria,1FDAT@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158397_k127_4313153_2	221288.JH992901_gene4218	9.352e-13	81.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1G5@1117|Cyanobacteria,1JJGJ@1189|Stigonemataceae	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158397_k127_4313153_1	1485545.JQLW01000007_gene735	1.711e-21	103.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	cNMP_binding
SRR25158397_k127_4313153_0	1382359.JIAL01000001_gene476	1.238e-44	177.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158397_k127_4314530_1	443143.GM18_0083	2.143e-79	273.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,43TZW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158397_k127_4314530_2	1459636.NTE_00013	1.878e-73	258.0	COG2085@1|root,arCOG00457@2157|Archaea	2157|Archaea	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored,HTH_10
SRR25158397_k127_4314530_0	518766.Rmar_0629	8.014e-87	294.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
SRR25158397_k127_4314865_0	883126.HMPREF9710_00737	9.72e-125	418.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,47743@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_4314865_2	398527.Bphyt_6345	9.188e-26	118.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,1KBSG@119060|Burkholderiaceae	28216|Betaproteobacteria	D	MreB/Mbl protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158397_k127_4314865_4	1122613.ATUP01000001_gene72	4.157e-05	53.0	COG2204@1|root,COG2204@2|Bacteria,1NSSP@1224|Proteobacteria,2UQF4@28211|Alphaproteobacteria,440NG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
SRR25158397_k127_4314865_1	522306.CAP2UW1_3526	8.488e-75	253.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158397_k127_4314865_3	1123508.JH636456_gene135	2.844e-12	67.0	COG2197@1|root,COG2197@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_4337195_7	272134.KB731324_gene6611	1.049e-32	141.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158397_k127_4337195_0	886293.Sinac_0383	2.69e-101	359.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158397_k127_4337195_4	1279019.ARQK01000049_gene38	1.23e-53	203.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158397_k127_4337195_3	861299.J421_4047	1.886e-55	209.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
SRR25158397_k127_4337195_2	861299.J421_4047	2.794e-57	214.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
SRR25158397_k127_4337195_1	1279009.ADICEAN_03773	1.481e-93	315.0	COG1028@1|root,COG1028@2|Bacteria,4NFK6@976|Bacteroidetes,47KDY@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158397_k127_4337195_6	1303518.CCALI_02718	3.35e-35	145.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158397_k127_4354740_1	903818.KI912268_gene2181	1.461e-76	289.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_4354740_4	1080067.BAZH01000034_gene2081	5.195e-07	59.0	2C543@1|root,32W3W@2|Bacteria,1N5UD@1224|Proteobacteria,1TKK8@1236|Gammaproteobacteria,3WXTD@544|Citrobacter	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4354740_3	118168.MC7420_5761	6.158e-11	74.0	2C3KV@1|root,2ZQNN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4354740_0	379066.GAU_2120	6.481e-124	417.0	COG1649@1|root,COG1649@2|Bacteria,1ZSWQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
SRR25158397_k127_4354740_2	485913.Krac_4762	6.894e-47	192.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,Trypsin
SRR25158397_k127_4361360_2	913325.N799_00590	3.697e-16	80.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1S1J7@1236|Gammaproteobacteria,1X5N3@135614|Xanthomonadales	135614|Xanthomonadales	I	Cardiolipin synthetase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158397_k127_4361360_0	1499967.BAYZ01000118_gene3299	3.759e-128	446.0	COG4953@1|root,COG4953@2|Bacteria,2NQMA@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
SRR25158397_k127_4361360_1	1047013.AQSP01000123_gene1545	2.812e-90	318.0	COG2373@1|root,COG2373@2|Bacteria,2NQA2@2323|unclassified Bacteria	2|Bacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
SRR25158397_k127_4380092_4	378806.STAUR_3211	5.462e-30	127.0	COG0589@1|root,COG0589@2|Bacteria,1Q5YW@1224|Proteobacteria,42RWD@68525|delta/epsilon subdivisions,2X3M5@28221|Deltaproteobacteria,2YWGY@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158397_k127_4380092_6	313595.P700755_003402	5.741e-06	58.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1I2YC@117743|Flavobacteriia,4C3V2@83612|Psychroflexus	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158397_k127_4380092_3	1242864.D187_003352	2.145e-42	162.0	COG2323@1|root,COG2323@2|Bacteria,1MW5I@1224|Proteobacteria,433KA@68525|delta/epsilon subdivisions,2WX8E@28221|Deltaproteobacteria,2Z11F@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158397_k127_4380092_7	1173025.GEI7407_1505	1.248e-05	53.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG4252@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4252@2|Bacteria,1G380@1117|Cyanobacteria,1HF14@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,Response_reg
SRR25158397_k127_4380092_1	42256.RradSPS_0960	2.397e-55	200.0	COG4288@1|root,COG4288@2|Bacteria,2IT13@201174|Actinobacteria,4CT9V@84995|Rubrobacteria	84995|Rubrobacteria	S	Anabaena sensory rhodopsin transducer	-	-	-	-	-	-	-	-	-	-	-	-	ASRT
SRR25158397_k127_4380092_2	1123368.AUIS01000006_gene679	6.93e-47	181.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1RP41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Gluconokinase	gntK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0046316	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iUTI89_1310.UTI89_C3945,iYL1228.KPN_03801	AAA_33,DctQ,SKI
SRR25158397_k127_4380092_0	314278.NB231_11189	3.859e-297	935.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158397_k127_4380092_5	1123368.AUIS01000006_gene679	5.326e-09	65.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1RP41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Gluconokinase	gntK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0046316	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iUTI89_1310.UTI89_C3945,iYL1228.KPN_03801	AAA_33,DctQ,SKI
SRR25158397_k127_4384593_5	357808.RoseRS_2131	1.878e-23	107.0	COG2062@1|root,COG2062@2|Bacteria,2GB93@200795|Chloroflexi,377KE@32061|Chloroflexia	32061|Chloroflexia	T	TIGRFAM phosphohistidine phosphatase SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158397_k127_4384593_1	1519464.HY22_08585	5.248e-76	274.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158397_k127_4384593_9	1123401.JHYQ01000009_gene2213	1.22e-11	66.0	COG4914@1|root,COG4914@2|Bacteria,1N1W1@1224|Proteobacteria,1ST82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4384593_6	1219035.NT2_02_04420	5.563e-19	99.0	2EA9M@1|root,334E1@2|Bacteria,1ND0N@1224|Proteobacteria	1224|Proteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158397_k127_4384593_2	448385.sce5067	1.571e-73	272.0	COG5492@1|root,COG5492@2|Bacteria,1QXT5@1224|Proteobacteria,43C5K@68525|delta/epsilon subdivisions,2X7FV@28221|Deltaproteobacteria,2YUV9@29|Myxococcales	28221|Deltaproteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4384593_0	246197.MXAN_0272	1.2e-118	414.0	COG1629@1|root,COG3087@1|root,COG1629@2|Bacteria,COG3087@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions,2X77J@28221|Deltaproteobacteria,2YUN6@29|Myxococcales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_4384593_10	103733.JNYO01000049_gene8379	9.404e-08	62.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DX7M@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	cseB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4384593_7	485913.Krac_5630	2.301e-13	79.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158397_k127_4384593_8	446468.Ndas_1353	2.695e-12	69.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,2GJB4@201174|Actinobacteria,4EG8R@85012|Streptosporangiales	201174|Actinobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158397_k127_4384593_4	35754.JNYJ01000037_gene4692	4.171e-32	146.0	COG5295@1|root,COG5297@1|root,COG5295@2|Bacteria,COG5297@2|Bacteria,2GK92@201174|Actinobacteria,4D9YE@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,Glyco_hydro_6
SRR25158397_k127_4384593_3	335543.Sfum_2355	2.404e-39	171.0	2DWMJ@1|root,3410X@2|Bacteria,1QZ4B@1224|Proteobacteria,42ZXH@68525|delta/epsilon subdivisions,2WV9B@28221|Deltaproteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4398430_2	234267.Acid_3259	1.538e-69	239.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158397_k127_4398430_0	1279009.ADICEAN_00512	1.949e-227	723.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158397_k127_4398430_3	886293.Sinac_5281	2.08e-40	166.0	COG2199@1|root,COG3706@2|Bacteria,2IZHZ@203682|Planctomycetes	203682|Planctomycetes	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF,HD,Response_reg
SRR25158397_k127_4398430_1	290397.Adeh_0531	6.55e-98	342.0	COG1752@1|root,COG1752@2|Bacteria,1N9HS@1224|Proteobacteria	1224|Proteobacteria	S	Patatin-like phospholipase	suhR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158397_k127_4398430_5	1328313.DS2_02003	0.0003329	49.0	2B2FA@1|root,31UZZ@2|Bacteria,1QSV3@1224|Proteobacteria,1RWFM@1236|Gammaproteobacteria,4699G@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4398430_4	391600.ABRU01000050_gene221	8.936e-18	87.0	COG0772@1|root,COG0772@2|Bacteria,1N2AA@1224|Proteobacteria,2UDQK@28211|Alphaproteobacteria,2KJA1@204458|Caulobacterales	204458|Caulobacterales	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4399193_2	1254432.SCE1572_30300	6.478e-70	249.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria,2YZY7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158397_k127_4399193_1	388413.ALPR1_16294	1.248e-113	371.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158397_k127_4399193_0	1242864.D187_007905	4.187e-191	609.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X3NE@28221|Deltaproteobacteria,2YWN3@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158397_k127_4404994_2	313606.M23134_02751	5.804e-149	490.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,47M24@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158397_k127_4404994_9	583345.Mmol_2327	5.504e-46	181.0	COG2114@1|root,COG2114@2|Bacteria,1PZ5K@1224|Proteobacteria,2W3A8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158397_k127_4404994_3	234267.Acid_4393	2.301e-147	499.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4404994_11	1173028.ANKO01000115_gene5830	5.399e-13	77.0	COG1073@1|root,COG1073@2|Bacteria,1G54F@1117|Cyanobacteria,1HAMN@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
SRR25158397_k127_4404994_7	215803.DB30_0760	6.226e-69	242.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2Z1ED@29|Myxococcales	28221|Deltaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SRR25158397_k127_4404994_6	1303518.CCALI_01109	9.271e-84	289.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158397_k127_4404994_5	861299.J421_1115	1.566e-87	297.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4404994_10	291985.CCSI01000002_gene1680	2.787e-42	163.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4404994_1	243231.GSU1636	7.65e-173	563.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158397_k127_4404994_12	63737.Npun_F0394	1.274e-05	55.0	COG4113@1|root,COG4113@2|Bacteria,1G6BG@1117|Cyanobacteria,1HQ44@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158397_k127_4404994_0	240015.ACP_0313	1.171e-197	625.0	COG3508@1|root,COG3508@2|Bacteria,3Y38R@57723|Acidobacteria,2JHM4@204432|Acidobacteriia	204432|Acidobacteriia	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158397_k127_4404994_8	234267.Acid_6517	2.699e-68	244.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria	57723|Acidobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4404994_4	1382359.JIAL01000001_gene713	2.365e-141	458.0	COG0179@1|root,COG0179@2|Bacteria,3Y442@57723|Acidobacteria,2JHIW@204432|Acidobacteriia	204432|Acidobacteriia	Q	Fumarylacetoacetase N-terminal	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158397_k127_4408302_1	1387312.BAUS01000012_gene1986	2.919e-106	355.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria,2KKN7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158397_k127_4408302_4	1173264.KI913949_gene1115	3.741e-58	230.0	COG0739@1|root,COG1404@1|root,COG4257@1|root,COG0739@2|Bacteria,COG1404@2|Bacteria,COG4257@2|Bacteria,1G7B0@1117|Cyanobacteria,1HBXD@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158397_k127_4408302_5	948106.AWZT01000114_gene1618	1.803e-51	206.0	2EZBT@1|root,33SH5@2|Bacteria,1NTX6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4408302_0	643473.KB235930_gene669	4.929e-150	508.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIE5@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_4408302_2	1254432.SCE1572_15860	2.565e-93	330.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2Z3N9@29|Myxococcales	28221|Deltaproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158397_k127_4408302_8	360911.EAT1b_2012	5.639e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,4HFU2@91061|Bacilli	91061|Bacilli	T	Chemotaxis protein CheY	phoP3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4408302_3	1267533.KB906733_gene3362	8.86e-63	239.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158397_k127_4408302_7	1380354.JIAN01000008_gene3362	6.273e-21	109.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
SRR25158397_k127_4408302_6	1385517.N800_04515	1.381e-26	128.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,Reprolysin_4,VPEP
SRR25158397_k127_4408302_9	1089545.KB913037_gene7872	1.497e-11	79.0	COG3209@1|root,COG3468@1|root,COG3209@2|Bacteria,COG3468@2|Bacteria,2GMBB@201174|Actinobacteria,4E3ST@85010|Pseudonocardiales	201174|Actinobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,TIG
SRR25158397_k127_4442301_3	1174528.JH992898_gene5340	2.905e-09	64.0	COG4188@1|root,COG4188@2|Bacteria,1GD7B@1117|Cyanobacteria	1117|Cyanobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SRR25158397_k127_4442301_1	479434.Sthe_0138	5.417e-58	218.0	COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K14645,ko:K17734	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158397_k127_4442301_0	1500897.JQNA01000002_gene4645	3.517e-124	421.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
SRR25158397_k127_4442301_2	886293.Sinac_1397	1.589e-26	127.0	COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4442301_4	452637.Oter_2330	0.0004132	44.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
SRR25158397_k127_4446800_5	1267534.KB906755_gene4691	3.187e-64	247.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4446800_4	1267533.KB906733_gene2989	1.351e-66	248.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158397_k127_4446800_2	452637.Oter_1515	8.598e-109	365.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158397_k127_4446800_3	1403819.BATR01000150_gene5076	3.304e-94	325.0	COG1136@1|root,COG1136@2|Bacteria,46UWZ@74201|Verrucomicrobia,2IVI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_4446800_1	452637.Oter_1513	2.882e-114	382.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_4446800_0	452637.Oter_1512	1.242e-121	419.0	COG0577@1|root,COG0577@2|Bacteria,46YY4@74201|Verrucomicrobia,3K9RN@414999|Opitutae	414999|Opitutae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4446800_7	290397.Adeh_3483	4.252e-26	111.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2YW4G@29|Myxococcales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158397_k127_4446800_6	767817.Desgi_4331	1.968e-32	129.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,25ZZ9@186807|Peptococcaceae	186801|Clostridia	D	TIGRFAM Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158397_k127_447882_1	1380391.JIAS01000013_gene3498	1.025e-100	363.0	COG3468@1|root,COG4447@1|root,COG3468@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2V8XE@28211|Alphaproteobacteria,2JXR9@204441|Rhodospirillales	204441|Rhodospirillales	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_447882_6	1248917.ANFX01000011_gene167	9.846e-39	168.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158397_k127_447882_5	234267.Acid_3725	1.396e-42	181.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158397_k127_447882_10	504832.OCAR_6759	4.111e-18	92.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Trans_reg_C
SRR25158397_k127_447882_13	595460.RRSWK_05444	2.72e-08	63.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
SRR25158397_k127_447882_14	1123256.KB907933_gene2276	7.522e-07	57.0	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,1SAZP@1236|Gammaproteobacteria,1XCW0@135614|Xanthomonadales	135614|Xanthomonadales	P	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158397_k127_447882_12	1291050.JAGE01000002_gene3870	3.846e-13	85.0	COG4733@1|root,COG4733@2|Bacteria,1UEBB@1239|Firmicutes,24DIX@186801|Clostridia	186801|Clostridia	N	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_447882_0	1128421.JAGA01000003_gene2811	8.594e-109	366.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158397_k127_447882_3	1125863.JAFN01000001_gene3506	1.967e-65	241.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SRR25158397_k127_447882_11	234267.Acid_0471	5.848e-18	98.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SRR25158397_k127_447882_2	289376.THEYE_A0564	5.5e-85	292.0	COG0379@1|root,COG0379@2|Bacteria,3J0NV@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158397_k127_447882_7	1500894.JQNN01000001_gene529	2.259e-38	155.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VZ36@28216|Betaproteobacteria,472UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158397_k127_447882_8	1121920.AUAU01000009_gene1956	3.469e-32	131.0	2BVXR@1|root,32QYG@2|Bacteria,3Y86A@57723|Acidobacteria	57723|Acidobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158397_k127_447882_4	1442599.JAAN01000014_gene3540	1.218e-59	214.0	COG4099@1|root,COG4099@2|Bacteria,1N4GB@1224|Proteobacteria,1RN51@1236|Gammaproteobacteria,1X50R@135614|Xanthomonadales	135614|Xanthomonadales	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158397_k127_4508793_11	1298865.H978DRAFT_3237	0.0001368	47.0	COG1073@1|root,COG1073@2|Bacteria,1RBII@1224|Proteobacteria,1S3JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158397_k127_4508793_6	861299.J421_0590	1.963e-46	169.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158397_k127_4508793_8	237368.SCABRO_03149	6.601e-13	74.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	RHH_1
SRR25158397_k127_4508793_10	1120948.KB903218_gene1791	3.393e-09	68.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	ycnE	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158397_k127_4508793_1	1379270.AUXF01000002_gene1363	4.83e-137	469.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158397_k127_4508793_9	383372.Rcas_3941	3.277e-09	69.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_4508793_5	331678.Cphamn1_0516	4.936e-71	263.0	COG4912@1|root,COG4912@2|Bacteria,1FDUX@1090|Chlorobi	1090|Chlorobi	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158397_k127_4508793_4	1403819.BATR01000162_gene5308	1.809e-87	301.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia,2IVBB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4508793_2	1449353.JQMQ01000005_gene2744	1.312e-111	372.0	COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,2NKEP@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SRR25158397_k127_4508793_0	234267.Acid_1201	1.035e-179	603.0	COG3591@1|root,COG3591@2|Bacteria,3Y2TU@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158397_k127_4508793_7	379066.GAU_3062	2.677e-35	138.0	COG1586@1|root,COG1586@2|Bacteria,1ZV1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
SRR25158397_k127_4508793_3	1121920.AUAU01000009_gene1851	1.552e-91	316.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158397_k127_4511302_2	521000.PROVRETT_06171	1.284e-29	127.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,3Z82I@586|Providencia	1236|Gammaproteobacteria	S	Psort location CytoplasmicMembrane, score 9.46	mgtC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158397_k127_4511302_1	1499967.BAYZ01000028_gene1281	8.639e-117	394.0	COG0747@1|root,COG0747@2|Bacteria,2NR54@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158397_k127_4511302_0	1267535.KB906767_gene5241	9.636e-119	410.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158397_k127_4515205_7	596152.DesU5LDRAFT_2187	1.974e-52	194.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2M9N9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	epsL	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SRR25158397_k127_4515205_4	383372.Rcas_3107	2.223e-70	265.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4515205_8	1380390.JIAT01000011_gene2712	3.699e-48	199.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4CSV6@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4515205_9	675635.Psed_1872	5.17e-36	151.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4E8Y4@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4515205_5	1123401.JHYQ01000021_gene1059	4.414e-67	253.0	COG1520@1|root,COG1520@2|Bacteria,1R4I1@1224|Proteobacteria,1SJ0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4515205_2	383372.Rcas_3107	1.239e-93	322.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4515205_6	930166.CD58_10415	5.97e-67	247.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	sypQ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158397_k127_4515205_13	1283287.KB822592_gene1274	1.795e-17	90.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4DPAD@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158397_k127_4515205_3	518766.Rmar_1316	5.057e-90	317.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1FJIC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158397_k127_4515205_14	1433287.X808_3350	6.301e-14	81.0	COG4632@1|root,COG4632@2|Bacteria,1PIAZ@1224|Proteobacteria,1T7WV@1236|Gammaproteobacteria,1Y9K5@135625|Pasteurellales	135625|Pasteurellales	G	XcbC of Neisseria meningitidis UniRef RepID Q7X4R9_NEIME	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
SRR25158397_k127_4515205_12	706587.Desti_4241	2.439e-21	101.0	COG2361@1|root,COG2361@2|Bacteria,1NA32@1224|Proteobacteria,43B8M@68525|delta/epsilon subdivisions,2X6MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158397_k127_4515205_11	706587.Desti_4240	1.695e-30	122.0	COG1669@1|root,COG1669@2|Bacteria,1N9G2@1224|Proteobacteria,42WM2@68525|delta/epsilon subdivisions,2WSBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158397_k127_4515205_1	309799.DICTH_1914	2.319e-154	501.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158397_k127_4515205_0	290397.Adeh_4278	5.365e-198	625.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria,2Z320@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158397_k127_4515205_10	1379698.RBG1_1C00001G1510	8.695e-36	157.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158397_k127_4521818_1	234267.Acid_0057	1.02e-126	442.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158397_k127_4521818_3	1121481.AUAS01000001_gene4679	3.241e-81	286.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158397_k127_4521818_0	1449346.JQMO01000003_gene2570	2.193e-130	428.0	COG0477@1|root,COG2814@2|Bacteria,2I4XI@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_4521818_2	159087.Daro_1528	1.653e-104	342.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2VK1P@28216|Betaproteobacteria,2KZ1Z@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158397_k127_4527005_1	1282665.H353_01215	2.488e-11	66.0	COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
SRR25158397_k127_4527005_0	768670.Calni_1067	1.353e-110	366.0	COG0825@1|root,COG0825@2|Bacteria,2GEY1@200930|Deferribacteres	200930|Deferribacteres	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158397_k127_4528937_5	1133849.O3I_021670	5.66e-45	189.0	COG1705@1|root,COG3108@1|root,COG1705@2|Bacteria,COG3108@2|Bacteria,2I9NY@201174|Actinobacteria	201174|Actinobacteria	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Hemopexin,Peptidase_M15_3
SRR25158397_k127_4528937_6	1038860.AXAP01000055_gene3528	3.662e-26	127.0	COG1705@1|root,COG1876@1|root,COG3409@1|root,COG1705@2|Bacteria,COG1876@2|Bacteria,COG3409@2|Bacteria,1Q6GA@1224|Proteobacteria,2VCM5@28211|Alphaproteobacteria,3K56M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MNU	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4528937_2	323261.Noc_2190	1.105e-114	380.0	2C2AK@1|root,30RHD@2|Bacteria,1NSEW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4528937_1	596152.DesU5LDRAFT_3311	1.615e-152	497.0	28JJ9@1|root,2Z9CC@2|Bacteria,1R4HT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4528937_0	323261.Noc_2193	5.75e-158	529.0	29UDG@1|root,30FQ4@2|Bacteria,1NQHT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4528937_3	1499967.BAYZ01000101_gene3596	2.993e-96	329.0	COG2204@1|root,COG2204@2|Bacteria,2NQQY@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,GAF_3,HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_4528937_7	4081.Solyc00g112490.1.1	1.35e-19	102.0	2ERUD@1|root,2SUIM@2759|Eukaryota,380XH@33090|Viridiplantae,3GQNT@35493|Streptophyta	35493|Streptophyta	S	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
SRR25158397_k127_4528937_4	316056.RPC_2708	2.301e-68	250.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,3JUBZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,DUF3494,PAP2,PATR
SRR25158397_k127_453569_3	1347368.HG964406_gene6385	9.754e-22	100.0	COG0454@1|root,COG0456@2|Bacteria,1TYX1@1239|Firmicutes,4IRK4@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158397_k127_453569_1	1245471.PCA10_43010	4.7e-97	344.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1YD7H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
SRR25158397_k127_453569_0	234267.Acid_7663	5.653e-145	464.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158397_k127_453569_2	1041159.AZUW01000062_gene3637	2.874e-40	161.0	COG1404@1|root,COG1404@2|Bacteria,1PSEZ@1224|Proteobacteria,2V4M5@28211|Alphaproteobacteria,4BFDK@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158397_k127_4537717_0	1382359.JIAL01000001_gene2279	2.464e-76	268.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158397_k127_4537717_1	204669.Acid345_3455	2.11e-61	220.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158397_k127_4537717_2	446468.Ndas_3551	1.343e-06	60.0	COG2304@1|root,COG2304@2|Bacteria,2GKDC@201174|Actinobacteria,4EHTV@85012|Streptosporangiales	201174|Actinobacteria	O	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	ADP_ribosyl_GH,DUF3520,VWA,vWF_A
SRR25158397_k127_4537717_3	1123377.AUIV01000026_gene572	0.0002118	53.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S2VT@1236|Gammaproteobacteria,1XCIY@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0810 Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_4539781_7	765910.MARPU_04185	3.12e-60	230.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
SRR25158397_k127_4539781_13	1254432.SCE1572_25970	8.8e-26	126.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CarboxypepD_reg,HemolysinCabind
SRR25158397_k127_4539781_6	153721.MYP_610	8.744e-61	220.0	COG0492@1|root,COG0492@2|Bacteria,4NPT9@976|Bacteroidetes,47XNY@768503|Cytophagia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158397_k127_4539781_0	215803.DB30_1529	5.201e-153	497.0	COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,433AE@68525|delta/epsilon subdivisions,2WYFQ@28221|Deltaproteobacteria,2YY3M@29|Myxococcales	28221|Deltaproteobacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
SRR25158397_k127_4539781_14	743722.Sph21_3862	9.873e-16	82.0	2EIK5@1|root,33CBF@2|Bacteria,4NV2P@976|Bacteroidetes,1IU6J@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4539781_3	68170.KL590510_gene7215	1.514e-76	261.0	COG3647@1|root,COG3647@2|Bacteria,2IATE@201174|Actinobacteria,4E3YF@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR25158397_k127_4539781_10	153721.MYP_2108	8.968e-58	230.0	COG2335@1|root,COG3509@1|root,COG2335@2|Bacteria,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,CBM_6,Esterase_phd,SLH
SRR25158397_k127_4539781_17	1089547.KB913013_gene2004	9.58e-05	55.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,47JAS@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
SRR25158397_k127_4539781_18	1089550.ATTH01000001_gene1503	0.0004343	52.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1FK2P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158397_k127_4539781_11	1267533.KB906736_gene1423	1.127e-38	168.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Peptidase_M43
SRR25158397_k127_4539781_8	40571.JOEA01000007_gene6594	8.787e-59	212.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4DYF4@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158397_k127_4539781_5	1174528.JH992898_gene4031	7.509e-61	216.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1JHEY@1189|Stigonemataceae	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158397_k127_4539781_4	118173.KB235914_gene2353	3.227e-74	276.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1H9PY@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158397_k127_4539781_9	1121123.AUAO01000002_gene186	8.83e-58	205.0	2E0U0@1|root,32WBK@2|Bacteria,1N6KE@1224|Proteobacteria,2UNUK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4539781_2	497964.CfE428DRAFT_2412	1.952e-81	276.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Phosphoglycerate mutase family	phoE	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158397_k127_4539781_1	234267.Acid_4535	2.578e-88	323.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158397_k127_454819_0	1300345.LF41_1045	5.759e-147	470.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQRJ@1236|Gammaproteobacteria,1X83S@135614|Xanthomonadales	135614|Xanthomonadales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158397_k127_454819_7	1121920.AUAU01000026_gene1478	1.936e-33	137.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_454819_9	1089553.Tph_c16200	9.8e-07	55.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia,42EKK@68295|Thermoanaerobacterales	186801|Clostridia	K	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
SRR25158397_k127_454819_3	1122604.JONR01000026_gene3004	6.727e-73	261.0	COG1409@1|root,COG1409@2|Bacteria,1R8W7@1224|Proteobacteria,1SSD6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158397_k127_454819_6	404589.Anae109_1544	4.38e-37	162.0	COG3791@1|root,COG4974@1|root,COG3791@2|Bacteria,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,42TG9@68525|delta/epsilon subdivisions,2WQ2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR25158397_k127_454819_8	1442599.JAAN01000041_gene3106	3.322e-16	91.0	COG0745@1|root,COG0745@2|Bacteria	1442599.JAAN01000041_gene3106|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_454819_4	189753.AXAS01000084_gene6056	4.18e-47	184.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,Guanylate_cyc,SAM_1,Trans_reg_C
SRR25158397_k127_454819_1	1121918.ARWE01000001_gene3122	6.319e-104	353.0	COG1752@1|root,COG1752@2|Bacteria,1Q4S1@1224|Proteobacteria,42S86@68525|delta/epsilon subdivisions,2WNJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158397_k127_454819_2	204669.Acid345_3314	1.815e-90	311.0	COG0578@1|root,COG0578@2|Bacteria,3Y2YF@57723|Acidobacteria,2JI40@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158397_k127_454819_5	443143.GM18_0192	8.253e-43	175.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SRR25158397_k127_454889_1	316067.Geob_1030	1.822e-216	696.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
SRR25158397_k127_454889_9	1121949.AQXT01000002_gene2170	2.792e-05	49.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,43YEU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158397_k127_454889_10	113355.CM001775_gene877	0.0009642	46.0	2EGU9@1|root,33AKF@2|Bacteria,1GB1Q@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158397_k127_454889_6	861299.J421_2234	3.457e-49	181.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	ykuD	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
SRR25158397_k127_454889_0	1519464.HY22_00255	0.0	1200.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158397_k127_454889_4	1121104.AQXH01000008_gene2418	1.542e-143	465.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158397_k127_454889_7	1382359.JIAL01000001_gene2441	1.041e-45	171.0	COG0457@1|root,COG0457@2|Bacteria,3Y4VN@57723|Acidobacteria,2JJG5@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
SRR25158397_k127_454889_5	404589.Anae109_1492	6.691e-120	404.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
SRR25158397_k127_454889_3	1122603.ATVI01000010_gene925	7.919e-173	568.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,1RR5C@1236|Gammaproteobacteria,1X46T@135614|Xanthomonadales	135614|Xanthomonadales	T	RecA-superfamily ATPases implicated in signal transduction	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158397_k127_454889_8	1396418.BATQ01000133_gene4021	2.879e-12	74.0	COG0745@1|root,COG0745@2|Bacteria,46TYS@74201|Verrucomicrobia,2IV90@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_454889_2	204669.Acid345_2913	1.982e-190	608.0	COG4805@1|root,COG4805@2|Bacteria,3Y3QB@57723|Acidobacteria,2JINM@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158397_k127_455418_1	479433.Caci_0783	3.282e-86	300.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158397_k127_455418_2	379066.GAU_0026	3.159e-73	259.0	COG1744@1|root,COG1744@2|Bacteria,1ZSMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158397_k127_455418_10	1382359.JIAL01000001_gene2867	1.381e-12	80.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_455418_0	289376.THEYE_A0208	2.947e-165	529.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3J0E0@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158397_k127_455418_4	1444309.JAQG01000005_gene4332	4.503e-45	171.0	COG3483@1|root,COG3483@2|Bacteria,1VTTH@1239|Firmicutes,4HU1U@91061|Bacilli	91061|Bacilli	E	Tryptophan 2,3-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_dioxygenase
SRR25158397_k127_455418_12	9258.ENSOANP00000022882	0.0003578	51.0	COG0457@1|root,KOG0548@2759|Eukaryota,38GCK@33154|Opisthokonta,3BECN@33208|Metazoa,3CUW9@33213|Bilateria,4806S@7711|Chordata,491B0@7742|Vertebrata,3JAZU@40674|Mammalia	33208|Metazoa	O	Hsp90 protein binding	STIP1	GO:0000003,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006950,GO:0007275,GO:0007568,GO:0008022,GO:0008150,GO:0008340,GO:0009266,GO:0009408,GO:0009628,GO:0010259,GO:0012505,GO:0030234,GO:0030544,GO:0031072,GO:0032501,GO:0032502,GO:0032780,GO:0032991,GO:0042030,GO:0043086,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0048856,GO:0050790,GO:0050896,GO:0051087,GO:0051336,GO:0051346,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772,GO:0101031	-	ko:K04734,ko:K09553,ko:K16362	ko04024,ko04062,ko04064,ko04210,ko04380,ko04620,ko04621,ko04622,ko04623,ko04624,ko04657,ko04658,ko04659,ko04660,ko04662,ko04668,ko04722,ko04920,ko04926,ko04931,ko05020,ko05120,ko05131,ko05134,ko05140,ko05142,ko05145,ko05160,ko05161,ko05162,ko05164,ko05166,ko05167,ko05168,ko05169,ko05200,ko05203,ko05215,ko05220,ko05222,map04024,map04062,map04064,map04210,map04380,map04620,map04621,map04622,map04623,map04624,map04657,map04658,map04659,map04660,map04662,map04668,map04722,map04920,map04926,map04931,map05020,map05120,map05131,map05134,map05140,map05142,map05145,map05160,map05161,map05162,map05164,map05166,map05167,map05168,map05169,map05200,map05203,map05215,map05220,map05222	M00686	-	-	ko00000,ko00001,ko00002,ko03000,ko03110,ko04131,ko04516	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
SRR25158397_k127_455418_8	1267535.KB906767_gene9	4.455e-22	105.0	COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158397_k127_455418_3	1267535.KB906767_gene4741	5.556e-47	177.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria,2JI9T@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR25158397_k127_455418_7	856793.MICA_1184	2.279e-26	113.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,4BQKE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158397_k127_455418_9	290397.Adeh_0266	7.929e-19	92.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158397_k127_455418_11	861299.J421_0824	1.249e-08	67.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	catD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158397_k127_455418_6	1121346.KB899861_gene340	1.752e-26	123.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli,274WM@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158397_k127_455418_5	1379698.RBG1_1C00001G0508	4.828e-37	143.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158397_k127_4555208_6	1267535.KB906767_gene1253	1.883e-52	190.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158397_k127_4555208_11	1123250.KB908445_gene11	2.482e-31	128.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158397_k127_4555208_4	1382359.JIAL01000001_gene1725	2.162e-104	347.0	COG0031@1|root,COG0031@2|Bacteria,3Y39Y@57723|Acidobacteria,2JJ08@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158397_k127_4555208_1	240015.ACP_1006	4.719e-151	496.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158397_k127_4555208_7	379066.GAU_3720	6.143e-46	175.0	28KW4@1|root,2ZACH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4555208_8	926566.Terro_0947	2.412e-41	161.0	COG0344@1|root,COG0344@2|Bacteria,3Y51D@57723|Acidobacteria,2JJFC@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158397_k127_4555208_5	1307759.JOMJ01000003_gene82	2.784e-90	307.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2M83G@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158397_k127_4555208_14	575540.Isop_1525	3.908e-18	99.0	COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4555208_15	1195236.CTER_2811	1.047e-17	92.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WGDE@541000|Ruminococcaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158397_k127_4555208_10	1488328.JMCL01000186_gene1480	2.777e-37	147.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1S99C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_4555208_19	1540221.JQNI01000002_gene1874	0.0004391	52.0	2DVTT@1|root,33X4Y@2|Bacteria,1WKIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
SRR25158397_k127_4555208_9	1211112.ALJC01000031_gene3522	6.251e-38	149.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1S99C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_4555208_13	1379698.RBG1_1C00001G0290	4.29e-19	98.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
SRR25158397_k127_4555208_16	1463920.JOGB01000015_gene1102	1.034e-08	68.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR25158397_k127_4555208_17	556261.HMPREF0240_04237	6.934e-06	53.0	COG2207@1|root,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia,36IQ0@31979|Clostridiaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
SRR25158397_k127_4555208_18	1448860.BBJO01000005_gene2367	0.0003354	48.0	arCOG13608@1|root,arCOG13608@2157|Archaea,2Y1PQ@28890|Euryarchaeota,23YR2@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4555208_12	1379698.RBG1_1C00001G0290	1.094e-20	108.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
SRR25158397_k127_4555208_0	1232410.KI421418_gene2189	0.0	1106.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43S61@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158397_k127_4555208_3	234267.Acid_7205	4.187e-128	435.0	COG0751@1|root,COG0751@2|Bacteria,3Y3KN@57723|Acidobacteria	57723|Acidobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRR25158397_k127_4555208_2	768670.Calni_0744	5.939e-129	417.0	COG0752@1|root,COG0752@2|Bacteria,2GEZ4@200930|Deferribacteres	200930|Deferribacteres	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRR25158397_k127_4557411_1	379066.GAU_0618	1.436e-60	217.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158397_k127_4557411_4	316274.Haur_0845	1.121e-25	120.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158397_k127_4557411_0	1340493.JNIF01000003_gene4549	5.197e-96	329.0	COG1104@1|root,COG1104@2|Bacteria,3Y389@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158397_k127_4557411_6	1047013.AQSP01000131_gene1842	1.006e-12	82.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
SRR25158397_k127_4557411_3	234267.Acid_6308	7.228e-31	142.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158397_k127_4557411_5	1047013.AQSP01000088_gene1634	3.297e-17	97.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
SRR25158397_k127_4557411_2	204669.Acid345_2058	1.252e-32	147.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158397_k127_4561326_2	404589.Anae109_2961	3.827e-105	369.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P6Q@68525|delta/epsilon subdivisions,2WKPS@28221|Deltaproteobacteria,2YXDB@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_4561326_6	344747.PM8797T_32485	1.969e-23	114.0	COG0517@1|root,COG0517@2|Bacteria,2J0FD@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158397_k127_4561326_3	794846.AJQU01000111_gene3208	1.032e-68	244.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158397_k127_4561326_4	1125863.JAFN01000001_gene1633	1.079e-40	158.0	COG1765@1|root,COG1765@2|Bacteria,1QF2G@1224|Proteobacteria,42UVN@68525|delta/epsilon subdivisions,2WQVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158397_k127_4561326_5	864051.BurJ1DRAFT_2134	1.202e-35	148.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2VVI3@28216|Betaproteobacteria,1KP7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4561326_1	246197.MXAN_6802	9.49e-178	569.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,42RN7@68525|delta/epsilon subdivisions,2WNNX@28221|Deltaproteobacteria,2Z317@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.14,1.2.1.46	ko:K00008,ko:K00148,ko:K18369	ko00040,ko00051,ko00625,ko00640,ko00680,ko01100,ko01120,ko01200,map00040,map00051,map00625,map00640,map00680,map01100,map01120,map01200	M00014	R00604,R00875,R01896,R10703	RC00085,RC00102,RC00188,RC00545	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158397_k127_4561326_0	1123242.JH636435_gene1922	3.59e-198	646.0	COG0474@1|root,COG0474@2|Bacteria,2IXV7@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158397_k127_4562256_5	234267.Acid_2549	3.516e-110	385.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria	57723|Acidobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158397_k127_4562256_6	861299.J421_4351	1.818e-106	374.0	COG0833@1|root,COG0833@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294,ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.2,2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
SRR25158397_k127_4562256_18	234267.Acid_3083	6.616e-12	78.0	COG3595@1|root,COG3595@2|Bacteria,3Y5AF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4562256_21	880073.Calab_3761	0.0002902	51.0	COG1462@1|root,COG1462@2|Bacteria,2NQ4P@2323|unclassified Bacteria	2|Bacteria	M	Curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF4384,FlgT_C,PG_binding_1
SRR25158397_k127_4562256_13	1158606.I579_00161	4.755e-81	282.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,4AZCE@81852|Enterococcaceae	91061|Bacilli	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158397_k127_4562256_11	1123288.SOV_2c05610	2.063e-93	313.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4H1WJ@909932|Negativicutes	909932|Negativicutes	E	ABC transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158397_k127_4562256_9	1379698.RBG1_1C00001G1349	2.242e-95	324.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158397_k127_4562256_7	189426.PODO_05665	9.602e-105	351.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,26URK@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158397_k127_4562256_2	1379698.RBG1_1C00001G1351	1.594e-126	420.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158397_k127_4562256_20	608538.HTH_0343	1.456e-10	70.0	COG1432@1|root,COG1432@2|Bacteria,2G51F@200783|Aquificae	200783|Aquificae	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158397_k127_4562256_0	1379698.RBG1_1C00001G0805	2.664e-187	603.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_4562256_16	373994.Riv7116_1144	1.804e-28	115.0	COG2442@1|root,COG2442@2|Bacteria,1G87F@1117|Cyanobacteria,1HPFU@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158397_k127_4562256_12	42256.RradSPS_2139	2.801e-92	327.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158397_k127_4562256_4	1379698.RBG1_1C00001G0806	2.006e-112	369.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158397_k127_4562256_1	316273.XCV0477	1.568e-162	574.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,LTD
SRR25158397_k127_4562256_14	1116232.AHBF01000007_gene1500	4.096e-58	234.0	COG1361@1|root,COG2373@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,2I8F1@201174|Actinobacteria	201174|Actinobacteria	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158397_k127_4562256_3	635013.TherJR_2349	1.541e-120	398.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158397_k127_4562256_17	926566.Terro_4202	6.891e-22	99.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158397_k127_4562256_8	335543.Sfum_0984	1.55e-96	337.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158397_k127_4562256_10	555079.Toce_1695	2.541e-94	321.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158397_k127_4562256_15	1125863.JAFN01000001_gene30	3.829e-46	174.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158397_k127_4562256_19	156889.Mmc1_3421	1.081e-11	65.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158397_k127_4563601_2	358220.C380_18695	1.32e-102	355.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,4AAME@80864|Comamonadaceae	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158397_k127_4563601_0	246197.MXAN_1666	4.948e-134	431.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria,4340G@68525|delta/epsilon subdivisions,2X4F0@28221|Deltaproteobacteria,2YYWA@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158397_k127_4563601_1	1095769.CAHF01000022_gene243	5.364e-108	372.0	COG4977@1|root,COG4977@2|Bacteria,1MXAU@1224|Proteobacteria,2WEWY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158397_k127_4563601_4	682795.AciX8_1416	6.882e-09	68.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
SRR25158397_k127_4563601_5	671143.DAMO_1180	3.82e-07	52.0	COG3177@1|root,COG3177@2|Bacteria,2NREB@2323|unclassified Bacteria	2|Bacteria	S	Filamentation induced by cAMP protein fic	fic	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158397_k127_4563601_3	743719.PaelaDRAFT_3761	6.019e-88	293.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,26UCG@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
SRR25158397_k127_4568736_1	666685.R2APBS1_2584	1.711e-08	55.0	COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158397_k127_4568736_0	378806.STAUR_2913	1.415e-193	617.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,437V8@68525|delta/epsilon subdivisions,2X34Q@28221|Deltaproteobacteria,2YU9A@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	dapE1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158397_k127_4568736_2	742738.HMPREF9460_03448	6.101e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24MBJ@186801|Clostridia,26B83@186813|unclassified Clostridiales	186801|Clostridia	K	Putative ATPase subunit of terminase (gpP-like)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_4568736_3	1449976.KALB_3093	5.334e-05	55.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E8G4@85010|Pseudonocardiales	201174|Actinobacteria	K	Anaphase-promoting complex subunit 5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,ANAPC5,BTAD,HTH_3,HTH_31,HTH_Crp_2,NB-ARC,TPR_10,TPR_12,TPR_7,Trans_reg_C,cNMP_binding
SRR25158397_k127_4576545_0	1267535.KB906767_gene3342	6.698e-134	442.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria,2JIF0@204432|Acidobacteriia	204432|Acidobacteriia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158397_k127_4576545_3	204669.Acid345_4024	6.542e-66	230.0	COG1309@1|root,COG1309@2|Bacteria,3Y5TS@57723|Acidobacteria,2JK51@204432|Acidobacteriia	204432|Acidobacteriia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158397_k127_4576545_1	1121438.JNJA01000007_gene1775	5.564e-72	262.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,42NKX@68525|delta/epsilon subdivisions,2WMAW@28221|Deltaproteobacteria,2M97Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_4576545_2	197221.22295567	3.521e-68	239.0	COG1136@1|root,COG1136@2|Bacteria,1G14U@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_4576545_12	502025.Hoch_2842	1.216e-05	57.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42T6A@68525|delta/epsilon subdivisions,2WPV8@28221|Deltaproteobacteria,2YUNA@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR25158397_k127_4576545_11	926554.KI912633_gene4039	1.285e-06	59.0	COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158397_k127_4576545_10	1192034.CAP_0611	4.058e-07	61.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SRR25158397_k127_4576545_4	1121033.AUCF01000040_gene780	1.901e-49	193.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2JPE1@204441|Rhodospirillales	204441|Rhodospirillales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158397_k127_4576545_8	1123060.JONP01000019_gene2919	4.808e-24	116.0	COG4188@1|root,COG4188@2|Bacteria,1R9J5@1224|Proteobacteria,2UDCI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SRR25158397_k127_4576545_5	1254432.SCE1572_04190	1.164e-36	155.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria	1224|Proteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158397_k127_4576545_9	324602.Caur_1269	6.858e-09	67.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
SRR25158397_k127_4576545_7	1292034.OR37_02962	6.089e-33	135.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158397_k127_4584105_2	215803.DB30_1448	1.525e-44	176.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2YVHM@29|Myxococcales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158397_k127_4584105_3	324602.Caur_0352	1.305e-28	125.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi,375N6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158397_k127_4584105_4	279010.BL03577	2.228e-10	73.0	COG1714@1|root,COG1714@2|Bacteria,1VIH4@1239|Firmicutes,4HSGI@91061|Bacilli,1ZF2E@1386|Bacillus	91061|Bacilli	S	membrane protein domain	yxaI	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158397_k127_4584105_5	1123253.AUBD01000002_gene1203	8.39e-10	68.0	COG1714@1|root,COG4969@1|root,COG1714@2|Bacteria,COG4969@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1X5Z4@135614|Xanthomonadales	135614|Xanthomonadales	NU	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158397_k127_4584105_6	398767.Glov_3582	3.043e-07	59.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4584105_1	443144.GM21_0895	2.348e-63	237.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158397_k127_4584105_0	1156937.MFUM_700138	3.882e-95	318.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,37G1U@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158397_k127_4586952_2	251221.35213336	5.154e-58	205.0	COG1718@1|root,COG1718@2|Bacteria,1G3HN@1117|Cyanobacteria	1117|Cyanobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4586952_1	521674.Plim_3844	1.446e-61	217.0	COG4894@1|root,COG4894@2|Bacteria,2J08U@203682|Planctomycetes	203682|Planctomycetes	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	Scramblase
SRR25158397_k127_4586952_0	880073.Calab_2714	4.833e-291	916.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,2NQKM@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
SRR25158397_k127_4589432_6	595460.RRSWK_04053	8.852e-14	78.0	COG2204@1|root,COG4567@1|root,COG2204@2|Bacteria,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
SRR25158397_k127_4589432_4	1144275.COCOR_04747	3.379e-39	158.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,42YFC@68525|delta/epsilon subdivisions,2X274@28221|Deltaproteobacteria,2YZ6A@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158397_k127_4589432_0	861299.J421_4340	1.022e-150	486.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158397_k127_4589432_5	1121013.P873_02115	3.669e-14	81.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1XDBG@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
SRR25158397_k127_4589432_1	1121430.JMLG01000037_gene147	2.61e-124	430.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRR25158397_k127_4589432_3	1944.JOAZ01000008_gene963	6.913e-98	330.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,417G5@629295|Streptomyces griseus group	2|Bacteria	J	tRNA synthetases class II core domain (F)	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	FDX-ACB,Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158397_k127_4589432_2	1944.JOAZ01000008_gene964	5.512e-120	412.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,41A0K@629295|Streptomyces griseus group	201174|Actinobacteria	J	tRNA synthetase B5 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158397_k127_4602357_10	1487953.JMKF01000081_gene4233	8.151e-21	95.0	COG4118@1|root,COG4118@2|Bacteria,1G8FZ@1117|Cyanobacteria,1HDKF@1150|Oscillatoriales	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158397_k127_4602357_8	449447.MAE_23820	1.964e-39	151.0	COG3744@1|root,COG3744@2|Bacteria,1G647@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_4602357_7	439235.Dalk_3847	8.221e-41	157.0	COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,42VRC@68525|delta/epsilon subdivisions,2WSEE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
SRR25158397_k127_4602357_11	225937.HP15_1151	1.275e-11	70.0	2ECQ9@1|root,336MY@2|Bacteria,1NE1E@1224|Proteobacteria	1224|Proteobacteria	S	ParD-like antitoxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like
SRR25158397_k127_4602357_6	1121920.AUAU01000004_gene815	6.279e-50	181.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158397_k127_4602357_4	1121920.AUAU01000004_gene816	6.364e-106	351.0	COG0410@1|root,COG0410@2|Bacteria,3Y9ED@57723|Acidobacteria	57723|Acidobacteria	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_4602357_3	243231.GSU2008	9.899e-119	386.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158397_k127_4602357_1	243231.GSU2007	3.819e-146	476.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158397_k127_4602357_2	243231.GSU2006	7.001e-138	443.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158397_k127_4602357_0	243231.GSU2005	1.72e-167	534.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158397_k127_4602357_9	153721.MYP_1916	1.36e-31	144.0	COG3746@1|root,COG3746@2|Bacteria,4NIA7@976|Bacteroidetes,47JKJ@768503|Cytophagia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4602357_5	483219.LILAB_02920	2.054e-58	215.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158397_k127_4610035_0	861299.J421_0679	0.0	1186.0	COG0178@1|root,COG0178@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158397_k127_4610035_4	1123242.JH636436_gene287	8.022e-20	93.0	COG0724@1|root,COG0724@2|Bacteria,2J0SR@203682|Planctomycetes	203682|Planctomycetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158397_k127_4610035_1	518766.Rmar_1363	6.904e-278	878.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4610035_2	1499967.BAYZ01000036_gene2419	4.742e-146	469.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158397_k127_4610035_3	398578.Daci_5074	2.514e-48	185.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158397_k127_4611008_7	1340493.JNIF01000003_gene1952	5.894e-08	54.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158397_k127_4611008_4	448385.sce1627	3.323e-30	132.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2YUR4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158397_k127_4611008_8	879212.DespoDRAFT_01510	5.76e-07	63.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2WKMG@28221|Deltaproteobacteria,2MPXI@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158397_k127_4611008_6	1125863.JAFN01000001_gene834	2.082e-12	75.0	COG1309@1|root,COG1309@2|Bacteria,1MV2V@1224|Proteobacteria,42NW6@68525|delta/epsilon subdivisions,2WPIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158397_k127_4611008_1	29581.BW37_04034	7.35e-63	243.0	COG3220@1|root,COG3220@2|Bacteria,1RH40@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
SRR25158397_k127_4611008_5	29581.BW37_04035	6.906e-30	136.0	2DPW6@1|root,333NE@2|Bacteria,1NM0S@1224|Proteobacteria,2W3RD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4611008_3	1380391.JIAS01000012_gene4519	4.991e-50	190.0	COG1746@1|root,COG1746@2|Bacteria,1RKKB@1224|Proteobacteria	1224|Proteobacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158397_k127_4611008_2	1033810.HLPCO_002271	5.11e-55	220.0	COG1404@1|root,COG1404@2|Bacteria,2NP8X@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	vpr	GO:0005575,GO:0005576	-	ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5
SRR25158397_k127_4611008_0	1206731.BAGB01000167_gene904	1.329e-120	426.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7
SRR25158397_k127_4620063_6	1385519.N801_08580	1.064e-05	59.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria,4FGKB@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158397_k127_4620063_5	99598.Cal7507_3725	3.818e-08	65.0	28PII@1|root,2ZC8H@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SRR25158397_k127_4620063_3	596153.Alide_1033	1.402e-19	98.0	2AAD4@1|root,30ZP1@2|Bacteria,1NBWF@1224|Proteobacteria,2VXBU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4620063_1	247490.KSU1_C0256	1.915e-50	184.0	2DB76@1|root,2Z7JZ@2|Bacteria,2IZMJ@203682|Planctomycetes	203682|Planctomycetes	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR25158397_k127_4620063_0	326427.Cagg_1505	2.691e-100	346.0	COG3497@1|root,COG3497@2|Bacteria,2G7YJ@200795|Chloroflexi,37730@32061|Chloroflexia	32061|Chloroflexia	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158397_k127_4620063_4	1040986.ATYO01000061_gene4964	3.814e-11	75.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158397_k127_4620063_2	419947.MRA_2103	3.363e-27	130.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,234QM@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknJ	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0032501,GO:0036211,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0046872,GO:0046914,GO:0048871,GO:0050897,GO:0065007,GO:0065008,GO:0071704,GO:0097009,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,PknH_C
SRR25158397_k127_4638093_2	903818.KI912268_gene1911	5.428e-48	182.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999,LptC,NLPC_P60,SH3_3
SRR25158397_k127_4638093_0	349521.HCH_01091	2.002e-141	463.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1XHPE@135619|Oceanospirillales	135619|Oceanospirillales	F	Guanine deaminase	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158397_k127_4638093_1	518766.Rmar_1860	3.7e-48	186.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1FJ14@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_4638093_5	1297742.A176_05036	2.581e-28	131.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158397_k127_4638093_4	1282360.ABAC460_05915	5.688e-44	175.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2KI46@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_4638093_3	234267.Acid_5523	2.793e-45	177.0	COG1651@1|root,COG1651@2|Bacteria,3Y87P@57723|Acidobacteria	2|Bacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158397_k127_4645315_2	290397.Adeh_3524	1.285e-68	256.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
SRR25158397_k127_4645315_0	335543.Sfum_1424	4.347e-165	529.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
SRR25158397_k127_4645315_5	1385521.N803_13875	1.256e-11	78.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4FGYK@85021|Intrasporangiaceae	201174|Actinobacteria	T	Signal peptide protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158397_k127_4645315_4	926569.ANT_06790	7.678e-23	114.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158397_k127_4645315_1	1227739.Hsw_3517	1.154e-101	349.0	COG2855@1|root,COG2855@2|Bacteria,4NES6@976|Bacteroidetes,47PE4@768503|Cytophagia	976|Bacteroidetes	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
SRR25158397_k127_4645315_3	1487953.JMKF01000053_gene1809	6.222e-62	223.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,1HA80@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158397_k127_4645457_7	1121104.AQXH01000001_gene1820	1.428e-46	175.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158397_k127_4645457_5	1128421.JAGA01000003_gene2894	8.324e-49	184.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158397_k127_4645457_6	243090.RB621	2.545e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158397_k127_4645457_2	935863.AWZR01000011_gene83	5.303e-68	263.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158397_k127_4645457_9	234267.Acid_3219	7.786e-17	96.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4645457_4	1210884.HG799465_gene12237	6.256e-49	178.0	COG0662@1|root,COG0662@2|Bacteria,2J42S@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158397_k127_4645457_3	1410620.SHLA_52c000040	3.374e-65	234.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,2U9JW@28211|Alphaproteobacteria,4BJ82@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
SRR25158397_k127_4645457_0	1337936.IJ00_01670	8.331e-133	443.0	COG1680@1|root,COG1680@2|Bacteria,1G5Z2@1117|Cyanobacteria,1HIVF@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158397_k127_4645457_1	1267533.KB906735_gene4786	1.432e-72	278.0	COG1629@1|root,COG1629@2|Bacteria,3Y3G2@57723|Acidobacteria,2JKEK@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_4645457_11	1122221.JHVI01000006_gene2377	1.65e-06	57.0	COG0068@1|root,COG0068@2|Bacteria,1WM7Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158397_k127_4645457_10	626939.HMPREF9443_01892	7.452e-12	65.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4H30X@909932|Negativicutes	909932|Negativicutes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158397_k127_4666168_0	1122611.KB903939_gene313	5.531e-86	303.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2H5BJ@201174|Actinobacteria	201174|Actinobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158397_k127_4666168_1	1121481.AUAS01000002_gene3509	9.109e-31	139.0	28QBS@1|root,2ZCUB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_466645_6	1206726.BAFV01000065_gene4502	6.673e-18	91.0	COG3832@1|root,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria,4G0ZK@85025|Nocardiaceae	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_466645_0	926560.KE387023_gene2479	2.832e-104	358.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158397_k127_466645_4	649638.Trad_2529	2.296e-51	202.0	COG1028@1|root,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158397_k127_466645_5	316274.Haur_1309	2.86e-41	159.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_466645_3	1128421.JAGA01000002_gene189	2.352e-67	243.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2NR1B@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	yhcY	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158397_k127_466645_2	497964.CfE428DRAFT_0572	1.009e-89	321.0	COG3488@1|root,COG3488@2|Bacteria,46T3U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SRR25158397_k127_466645_1	497964.CfE428DRAFT_0572	1.283e-93	323.0	COG3488@1|root,COG3488@2|Bacteria,46T3U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SRR25158397_k127_4666875_2	1267535.KB906767_gene2297	1.259e-82	279.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria,2JMQ5@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158397_k127_4666875_1	1267535.KB906767_gene2296	2.084e-88	308.0	COG4585@1|root,COG4585@2|Bacteria,3Y59R@57723|Acidobacteria	2|Bacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA_3,PAS,PAS_9,Pkinase
SRR25158397_k127_4666875_3	405948.SACE_2447	5.311e-19	102.0	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,2I2IT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-phosphoglucomutase family hydrolase	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Trehalose_PPase
SRR25158397_k127_4666875_0	1430440.MGMSRv2_2570	5.213e-156	507.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,2JPVA@204441|Rhodospirillales	204441|Rhodospirillales	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158397_k127_4666875_4	518766.Rmar_0501	1.895e-08	63.0	COG3769@1|root,COG3769@2|Bacteria,4P1MD@976|Bacteroidetes	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158397_k127_4686346_7	197221.22295064	1.182e-12	70.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SRR25158397_k127_4686346_6	1123072.AUDH01000002_gene2474	1.937e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2JPZV@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4686346_3	574087.Acear_0893	1.938e-65	229.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WAIW@53433|Halanaerobiales	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
SRR25158397_k127_4686346_1	1121430.JMLG01000006_gene1764	8.793e-106	359.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,260AV@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158397_k127_4686346_0	671143.DAMO_2139	2.911e-130	443.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158397_k127_4686346_5	316067.Geob_2909	4.923e-19	102.0	COG0745@1|root,COG0745@2|Bacteria,1N0WF@1224|Proteobacteria,42TTF@68525|delta/epsilon subdivisions,2WR69@28221|Deltaproteobacteria,43SMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_4686346_2	404589.Anae109_3433	1.125e-99	342.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158397_k127_4686346_4	1242864.D187_001696	1.539e-54	193.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158397_k127_4688543_5	1288963.ADIS_4682	2.584e-33	132.0	COG3832@1|root,COG3832@2|Bacteria,4NTMD@976|Bacteroidetes,47SP5@768503|Cytophagia	976|Bacteroidetes	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158397_k127_4688543_3	1047013.AQSP01000033_gene1389	4.762e-61	227.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158397_k127_4688543_7	391619.PGA1_c14090	6.614e-29	125.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,34F34@302485|Phaeobacter	28211|Alphaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158397_k127_4688543_0	439375.Oant_2274	8.117e-175	558.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,1J2N3@118882|Brucellaceae	28211|Alphaproteobacteria	I	ATP-grasp domain	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158397_k127_4688543_6	1047013.AQSP01000042_gene405	2.83e-32	131.0	COG0511@1|root,COG0511@2|Bacteria,2NPT1@2323|unclassified Bacteria	2|Bacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl
SRR25158397_k127_4688543_11	290397.Adeh_0647	1.002e-13	76.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,2YVP4@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4688543_15	944480.ATUV01000002_gene30	9.826e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1Q6R4@1224|Proteobacteria,439NS@68525|delta/epsilon subdivisions,2X504@28221|Deltaproteobacteria,2M74N@213113|Desulfurellales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_19,TPR_8
SRR25158397_k127_4688543_10	1245469.S58_38650	7.976e-19	102.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2U1BI@28211|Alphaproteobacteria,3JVY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
SRR25158397_k127_4688543_2	1047013.AQSP01000124_gene2676	1.528e-100	359.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158397_k127_4688543_8	1047013.AQSP01000124_gene2678	2.901e-23	108.0	COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria	2|Bacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR25158397_k127_4688543_13	1047013.AQSP01000124_gene2679	3.623e-11	75.0	COG3166@1|root,COG3166@2|Bacteria,2NRP1@2323|unclassified Bacteria	2|Bacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SRR25158397_k127_4688543_1	243231.GSU2032	9.075e-102	342.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,43UK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158397_k127_4688543_9	1382304.JNIL01000001_gene667	2.215e-20	93.0	COG0227@1|root,COG0227@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158397_k127_4688543_14	880070.Cycma_2765	1.155e-10	69.0	COG0671@1|root,COG0671@2|Bacteria,4NTAH@976|Bacteroidetes	976|Bacteroidetes	I	ABC transporter (Permease)	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158397_k127_4688543_4	378806.STAUR_2892	3.35e-47	183.0	COG0665@1|root,COG0665@2|Bacteria,1NCJX@1224|Proteobacteria,431XD@68525|delta/epsilon subdivisions,2WWSZ@28221|Deltaproteobacteria,2YUQQ@29|Myxococcales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.3	ko:K00273	ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146	-	R00366,R02457,R02894,R02923,R04221,R07400	RC00006,RC00018,RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158397_k127_4693279_12	404589.Anae109_4096	2.248e-50	191.0	COG1538@1|root,COG1538@2|Bacteria,1PKT6@1224|Proteobacteria,4354V@68525|delta/epsilon subdivisions,2X95H@28221|Deltaproteobacteria,2Z21V@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158397_k127_4693279_4	404589.Anae109_4095	8.426e-144	476.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,42SFA@68525|delta/epsilon subdivisions,2WUV2@28221|Deltaproteobacteria,2YVKJ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158397_k127_4693279_1	404589.Anae109_4094	0.0	1437.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SRR25158397_k127_4693279_14	671143.DAMO_2589	2.497e-41	160.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
SRR25158397_k127_4693279_11	1278073.MYSTI_01043	5.936e-52	199.0	COG1538@1|root,COG1538@2|Bacteria,1R6VY@1224|Proteobacteria	1224|Proteobacteria	MU	PFAM Outer membrane efflux protein	cecC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158397_k127_4693279_6	1144275.COCOR_04355	1.527e-104	353.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR25158397_k127_4693279_0	246197.MXAN_0983	0.0	1470.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR25158397_k127_4693279_9	234267.Acid_3868	2.071e-62	225.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158397_k127_4693279_13	399739.Pmen_1247	6.303e-42	158.0	COG1742@1|root,COG1742@2|Bacteria,1MZI8@1224|Proteobacteria,1SB33@1236|Gammaproteobacteria,1YGI8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Uncharacterised BCR, YnfA/UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
SRR25158397_k127_4693279_8	1254432.SCE1572_48160	2.33e-65	228.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2X520@28221|Deltaproteobacteria,2Z004@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158397_k127_4693279_17	666685.R2APBS1_1415	2.206e-12	71.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158397_k127_4693279_2	1125863.JAFN01000001_gene1462	0.0	1103.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158397_k127_4693279_3	941639.BCO26_2934	3.525e-175	581.0	COG0513@1|root,COG1199@1|root,COG0513@2|Bacteria,COG1199@2|Bacteria,1URXJ@1239|Firmicutes,4HF1N@91061|Bacilli,1ZG9U@1386|Bacillus	91061|Bacilli	L	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2,ResIII
SRR25158397_k127_4693279_5	208439.AJAP_38345	5.411e-107	356.0	COG0596@1|root,COG0596@2|Bacteria,2I8FT@201174|Actinobacteria	201174|Actinobacteria	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158397_k127_4693279_10	457429.ABJI02000741_gene333	5.217e-53	194.0	COG1018@1|root,COG1018@2|Bacteria,2IN34@201174|Actinobacteria	201174|Actinobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4693279_7	1122176.KB903551_gene4256	1.562e-90	317.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,1IU97@117747|Sphingobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158397_k127_4693279_18	1317118.ATO8_20784	4.381e-08	65.0	COG0845@1|root,COG3260@1|root,COG3261@1|root,COG0845@2|Bacteria,COG3260@2|Bacteria,COG3261@2|Bacteria,1Q4AR@1224|Proteobacteria,2U5X4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CM	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa
SRR25158397_k127_4693279_16	232721.Ajs_2670	3.997e-21	108.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2VIIW@28216|Betaproteobacteria,4AAW2@80864|Comamonadaceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	copB	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158397_k127_4695649_1	309807.SRU_1913	1.276e-30	122.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1FJB2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158397_k127_4695649_0	439235.Dalk_4490	3.841e-71	252.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
SRR25158397_k127_4695649_2	1033743.CAES01000007_gene1979	1.327e-25	117.0	COG2006@1|root,COG2006@2|Bacteria,1UMYS@1239|Firmicutes,4IU3I@91061|Bacilli,26YEM@186822|Paenibacillaceae	91061|Bacilli	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158397_k127_4695649_3	1232410.KI421412_gene388	1.436e-08	68.0	COG5276@1|root,COG5276@2|Bacteria,1RBM1@1224|Proteobacteria,42TF9@68525|delta/epsilon subdivisions,2WPX5@28221|Deltaproteobacteria,43SNG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158397_k127_4695649_4	45351.EDO32442	1.247e-05	53.0	KOG1892@1|root,KOG1892@2759|Eukaryota,3976T@33154|Opisthokonta,3BCJ6@33208|Metazoa	33208|Metazoa	Z	adherens junction organization	MLLT4	GO:0000132,GO:0000165,GO:0000226,GO:0000278,GO:0000902,GO:0001654,GO:0001700,GO:0001736,GO:0001738,GO:0001745,GO:0001885,GO:0001932,GO:0002009,GO:0002064,GO:0002065,GO:0003158,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0005912,GO:0005913,GO:0005915,GO:0005924,GO:0005926,GO:0005938,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007154,GO:0007155,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007219,GO:0007254,GO:0007264,GO:0007265,GO:0007267,GO:0007275,GO:0007389,GO:0007391,GO:0007392,GO:0007394,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0008283,GO:0008360,GO:0008544,GO:0009653,GO:0009790,GO:0009792,GO:0009826,GO:0009887,GO:0009888,GO:0009966,GO:0009987,GO:0010001,GO:0010646,GO:0014009,GO:0014013,GO:0016020,GO:0016043,GO:0016049,GO:0016310,GO:0016318,GO:0016330,GO:0016331,GO:0016476,GO:0016604,GO:0016607,GO:0017016,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0021537,GO:0021543,GO:0021987,GO:0022008,GO:0022402,GO:0022603,GO:0022604,GO:0022610,GO:0023014,GO:0023051,GO:0023052,GO:0030010,GO:0030054,GO:0030055,GO:0030154,GO:0030274,GO:0030855,GO:0030900,GO:0031098,GO:0031267,GO:0031323,GO:0031399,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032872,GO:0032879,GO:0032880,GO:0032989,GO:0033036,GO:0033554,GO:0034330,GO:0034331,GO:0034332,GO:0034334,GO:0035556,GO:0036211,GO:0040001,GO:0040007,GO:0042063,GO:0042067,GO:0042127,GO:0042325,GO:0042592,GO:0043085,GO:0043087,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043296,GO:0043408,GO:0043412,GO:0043547,GO:0043954,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045177,GO:0045216,GO:0045446,GO:0045595,GO:0045995,GO:0046328,GO:0048468,GO:0048513,GO:0048583,GO:0048589,GO:0048592,GO:0048598,GO:0048699,GO:0048729,GO:0048730,GO:0048731,GO:0048749,GO:0048854,GO:0048856,GO:0048869,GO:0048872,GO:0050767,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050896,GO:0051020,GO:0051128,GO:0051171,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051293,GO:0051294,GO:0051336,GO:0051345,GO:0051403,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051716,GO:0051960,GO:0060019,GO:0060255,GO:0060284,GO:0060322,GO:0060429,GO:0060560,GO:0060563,GO:0061028,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070161,GO:0070302,GO:0070445,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090557,GO:0090596,GO:0099568,GO:1901564,GO:1902414,GO:1902531,GO:1902850,GO:1903047,GO:2000026,GO:2000177	-	ko:K05702	ko04014,ko04015,ko04024,ko04520,ko04530,ko04670,map04014,map04015,map04024,map04520,map04530,map04670	-	-	-	ko00000,ko00001	-	-	-	DIL,FHA,PDZ,RA
SRR25158397_k127_4713895_0	1037409.BJ6T_09690	7.254e-124	407.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1N207@1224|Proteobacteria,2UEQQ@28211|Alphaproteobacteria,3JWDD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
SRR25158397_k127_4713895_4	1506583.JQJY01000008_gene3779	5.053e-08	65.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,4NPAU@976|Bacteroidetes,1I2QH@117743|Flavobacteriia,2NYMD@237|Flavobacterium	976|Bacteroidetes	M	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	SprB,VWA_2
SRR25158397_k127_4713895_3	391937.NA2_06837	2.068e-24	109.0	COG5470@1|root,COG5470@2|Bacteria,1PJHZ@1224|Proteobacteria,2UDNK@28211|Alphaproteobacteria,43QKC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158397_k127_4713895_5	1121920.AUAU01000014_gene2821	4.365e-07	57.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_4713895_2	234267.Acid_3176	5.034e-32	141.0	COG0346@1|root,COG0346@2|Bacteria,3Y8C4@57723|Acidobacteria	57723|Acidobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_4713895_1	1502852.FG94_03132	2.518e-119	391.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,476SF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_4715319_6	1267005.KB911258_gene295	2.416e-05	57.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VEXA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Two component Transcriptional regulator, winged helix family	-	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4715319_1	1121013.P873_00390	1.883e-88	305.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria	1224|Proteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158397_k127_4715319_3	1192034.CAP_6791	4.003e-13	79.0	2C4KT@1|root,340PA@2|Bacteria,1NYVI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4715319_0	1121013.P873_00385	7.794e-187	608.0	COG0464@1|root,COG0464@2|Bacteria,1RCHW@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158397_k127_4715319_5	1242864.D187_003993	1.209e-06	58.0	2ESNI@1|root,33K73@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SRR25158397_k127_4715319_2	1288494.EBAPG3_30900	3.835e-66	237.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,Dala_Dala_lig_C,RimK
SRR25158397_k127_4735425_2	886293.Sinac_6292	4.983e-100	363.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
SRR25158397_k127_4735425_0	234267.Acid_5939	1.433e-130	433.0	COG1807@1|root,COG1807@2|Bacteria,3Y383@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_4735425_4	1121456.ATVA01000013_gene1130	2.828e-31	136.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158397_k127_4735425_5	100226.SCO3458	9.996e-22	107.0	COG0398@1|root,COG0398@2|Bacteria,2GN68@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_4735425_3	234267.Acid_2376	1.422e-32	140.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23
SRR25158397_k127_4735425_1	1384057.CD33_05915	4.807e-111	367.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3IX50@400634|Lysinibacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158397_k127_4735778_7	1502852.FG94_00591	5.567e-58	206.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,2WE5M@28216|Betaproteobacteria,4771T@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
SRR25158397_k127_4735778_9	215803.DB30_7652	1.551e-33	148.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YTWF@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
SRR25158397_k127_4735778_8	1430440.MGMSRv2_1777	3.94e-53	209.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,2TWBW@28211|Alphaproteobacteria,2JPN9@204441|Rhodospirillales	204441|Rhodospirillales	T	Stimulus-sensing domain	chvG	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
SRR25158397_k127_4735778_5	1397666.RS24_01747	6.662e-66	232.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,4BPV5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	chvI	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4735778_3	1237149.C900_00776	4.285e-98	348.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,47NWS@768503|Cytophagia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
SRR25158397_k127_4735778_4	143224.JQMD01000002_gene3435	4.02e-66	232.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,1I1J9@117743|Flavobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158397_k127_4735778_10	1122134.KB893650_gene305	2.196e-27	119.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158397_k127_4735778_6	1380394.JADL01000009_gene3149	4.376e-58	213.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,2JWUA@204441|Rhodospirillales	204441|Rhodospirillales	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158397_k127_4735778_1	1384056.N787_06630	1.63e-130	426.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158397_k127_4735778_2	639030.JHVA01000001_gene2812	5.307e-99	329.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
SRR25158397_k127_4735778_0	378806.STAUR_3171	3.508e-243	771.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158397_k127_4738656_8	1536775.H70737_28195	1.678e-24	107.0	COG0451@1|root,COG0451@2|Bacteria,1UD17@1239|Firmicutes,4IPHI@91061|Bacilli,2721G@186822|Paenibacillaceae	91061|Bacilli	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158397_k127_4738656_3	1267005.KB911257_gene665	2.297e-81	284.0	COG3510@1|root,COG3510@2|Bacteria,1MWJ8@1224|Proteobacteria,2U3D6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	cephalosporin hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	CmcI
SRR25158397_k127_4738656_12	240016.ABIZ01000001_gene2517	1.023e-06	62.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.60	ko:K07011,ko:K13005	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_2
SRR25158397_k127_4738656_11	1048339.KB913029_gene4413	3.424e-08	67.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_4738656_13	506534.Rhein_1658	0.0006992	53.0	COG1216@1|root,COG1216@2|Bacteria,1PG64@1224|Proteobacteria,1SNP4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_4738656_4	224911.27351908	1.382e-71	265.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2V82Q@28211|Alphaproteobacteria,3JZF5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4738656_7	1128421.JAGA01000004_gene2683	5.115e-38	149.0	COG0110@1|root,COG1086@1|root,COG0110@2|Bacteria,COG1086@2|Bacteria,2NPWU@2323|unclassified Bacteria	2|Bacteria	GM	Bacterial transferase hexapeptide (six repeats)	pseB	-	4.2.1.115	ko:K13006,ko:K15673,ko:K15894	ko00520,ko01051,ko01052,map00520,map01051,map01052	-	R09697	RC02609	ko00000,ko00001,ko01000,ko01005,ko01008	-	-	-	Hexapep,Polysacc_synt_2
SRR25158397_k127_4738656_5	224911.27351908	1.756e-60	232.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2V82Q@28211|Alphaproteobacteria,3JZF5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4738656_0	383372.Rcas_1361	1.842e-112	381.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi,3765I@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158397_k127_4738656_10	1500281.JQKZ01000021_gene2688	2.305e-15	81.0	2EC1F@1|root,3360K@2|Bacteria,4NX6U@976|Bacteroidetes,1IB6U@117743|Flavobacteriia,3ZTYT@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF3892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3892
SRR25158397_k127_4738656_2	443144.GM21_0838	3.713e-89	299.0	COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,42SK8@68525|delta/epsilon subdivisions,2WPU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158397_k127_4738656_9	32057.KB217483_gene9996	8.499e-17	93.0	2EE4N@1|root,337ZA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4738656_6	62928.azo2614	4.916e-38	151.0	2E5ES@1|root,3306N@2|Bacteria,1N5VN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4738656_1	1121935.AQXX01000116_gene5196	9.096e-106	370.0	COG3447@1|root,COG5001@1|root,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1
SRR25158397_k127_4743953_10	13035.Dacsa_1178	3.793e-29	131.0	COG2027@1|root,COG2027@2|Bacteria,1G1K9@1117|Cyanobacteria	1117|Cyanobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158397_k127_4743953_5	1340493.JNIF01000003_gene4835	4.043e-110	385.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	ampH	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158397_k127_4743953_14	1401065.HMPREF2130_04105	1.174e-05	56.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,3T338@506|Alcaligenaceae	28216|Betaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158397_k127_4743953_15	207954.MED92_07556	0.0001317	49.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,1XRJ4@135619|Oceanospirillales	135619|Oceanospirillales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4743953_13	1090319.KE386571_gene437	5.429e-09	66.0	2EBPI@1|root,335PM@2|Bacteria,1R3KC@1224|Proteobacteria,2UNS1@28211|Alphaproteobacteria,2K160@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4743953_2	639030.JHVA01000001_gene1643	4.441e-189	612.0	COG3590@1|root,COG3590@2|Bacteria,3Y31X@57723|Acidobacteria,2JIDI@204432|Acidobacteriia	204432|Acidobacteriia	O	peptidase	-	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158397_k127_4743953_3	448385.sce2299	2.943e-174	559.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWKI@29|Myxococcales	28221|Deltaproteobacteria	H	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158397_k127_4743953_4	246197.MXAN_0260	4.156e-112	375.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2WQ9K@28221|Deltaproteobacteria,2YXTM@29|Myxococcales	28221|Deltaproteobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158397_k127_4743953_9	449447.MAE_12770	9.178e-39	159.0	COG0824@1|root,COG0824@2|Bacteria,1GDHP@1117|Cyanobacteria	1117|Cyanobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K15315	ko01059,map01059	-	R11436	RC00039,RC03437	ko00000,ko00001,ko01008	-	-	-	4HBT_2
SRR25158397_k127_4743953_11	246197.MXAN_3277	1.104e-25	109.0	COG2128@1|root,COG2128@2|Bacteria,1Q58P@1224|Proteobacteria,43A55@68525|delta/epsilon subdivisions,2WZAF@28221|Deltaproteobacteria,2Z1PY@29|Myxococcales	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4743953_12	1144275.COCOR_03019	3.039e-18	96.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158397_k127_4743953_0	443255.SCLAV_p1350	0.0	1276.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	ko:K13611,ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01004,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158397_k127_4743953_6	1242864.D187_003116	6.244e-109	368.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,42SJE@68525|delta/epsilon subdivisions,2WPS5@28221|Deltaproteobacteria,2YWQM@29|Myxococcales	28221|Deltaproteobacteria	C	Retinal pigment epithelial membrane protein	-	-	1.13.11.75	ko:K00464	-	-	R09601	RC00912	ko00000,ko01000	-	-	-	RPE65,TAT_signal
SRR25158397_k127_4743953_1	479433.Caci_6353	6.538e-265	828.0	COG0644@1|root,COG0644@2|Bacteria,2GIWW@201174|Actinobacteria	201174|Actinobacteria	C	halogenase	-	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
SRR25158397_k127_4743953_7	1267534.KB906756_gene611	9.829e-51	192.0	COG2267@1|root,COG2267@2|Bacteria,3Y4GV@57723|Acidobacteria,2JJ2R@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158397_k127_4743953_8	867900.Celly_0996	3.005e-45	167.0	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4763593_2	593750.Metfor_1976	1.519e-31	139.0	COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea,2Y2MD@28890|Euryarchaeota	2157|Archaea	T	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
SRR25158397_k127_4763593_1	1192034.CAP_1602	1.349e-112	371.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158397_k127_4763593_4	1288079.AUKN01000005_gene4979	0.0004839	52.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,2GNKQ@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
SRR25158397_k127_4763593_3	1279017.AQYJ01000026_gene127	2.233e-09	67.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,1S5X5@1236|Gammaproteobacteria,467HX@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	Peptidase S24-like	umuD	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009355,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158397_k127_4763593_0	713586.KB900536_gene926	4.723e-151	484.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158397_k127_476514_6	344747.PM8797T_13947	5.59e-29	133.0	COG1520@1|root,COG1572@1|root,COG2373@1|root,COG2931@1|root,COG3203@1|root,COG3266@1|root,COG3391@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3203@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
SRR25158397_k127_476514_0	1382359.JIAL01000001_gene2955	3.181e-123	404.0	COG0180@1|root,COG0180@2|Bacteria,3Y2VN@57723|Acidobacteria,2JHXI@204432|Acidobacteriia	204432|Acidobacteriia	J	aminoacyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158397_k127_476514_4	1120971.AUCA01000019_gene1107	1.437e-40	163.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,279W3@186823|Alicyclobacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158397_k127_476514_5	234267.Acid_6490	3.004e-40	158.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158397_k127_476514_1	1121468.AUBR01000014_gene2214	1.201e-71	252.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158397_k127_476514_3	1232410.KI421418_gene2307	8.244e-51	191.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,43VZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158397_k127_476514_2	880072.Desac_0024	6.496e-60	214.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MR1P@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158397_k127_4784215_1	1168059.KB899087_gene2961	8.851e-104	342.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,3EYTB@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158397_k127_4784215_6	1449347.JQLN01000005_gene4496	8.429e-14	86.0	COG0726@1|root,COG0726@2|Bacteria,2IBGP@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4784215_2	204669.Acid345_2980	1.258e-59	237.0	COG2373@1|root,COG2931@1|root,COG3391@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,3Y59J@57723|Acidobacteria,2JJUR@204432|Acidobacteriia	204432|Acidobacteriia	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,VCBS
SRR25158397_k127_4784215_5	367299.JOEE01000003_gene2669	1.187e-14	89.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,Big_5,CarboxypepD_reg,DUF11,DUF3494,SdrD_B,TIG,fn3
SRR25158397_k127_4784215_4	1123508.JH636453_gene5800	7.664e-47	196.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158397_k127_4784215_3	1121422.AUMW01000008_gene477	1.109e-47	187.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,261FX@186807|Peptococcaceae	186801|Clostridia	S	PFAM Rhomboid family protein	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158397_k127_4784215_0	326427.Cagg_1968	2.57e-123	407.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi,3772V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158397_k127_4798326_2	1267535.KB906767_gene3342	1.572e-36	141.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria,2JIF0@204432|Acidobacteriia	204432|Acidobacteriia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158397_k127_4798326_1	1449063.JMLS01000001_gene4223	1.174e-43	172.0	COG2971@1|root,COG2971@2|Bacteria,1V87Z@1239|Firmicutes,4HJ58@91061|Bacilli,276KV@186822|Paenibacillaceae	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158397_k127_4798326_0	768710.DesyoDRAFT_1372	9.925e-110	369.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158397_k127_4804120_3	1444711.CCJF01000005_gene259	3.248e-59	223.0	COG0564@1|root,COG0564@2|Bacteria,2JG28@204428|Chlamydiae	204428|Chlamydiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158397_k127_4804120_4	93220.LV28_24150	5.617e-33	140.0	COG0457@1|root,COG0457@2|Bacteria	93220.LV28_24150|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4804120_2	880073.Calab_2988	1.521e-75	261.0	COG2013@1|root,COG2013@2|Bacteria,2NQA0@2323|unclassified Bacteria	2|Bacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR25158397_k127_4804120_1	321332.CYB_1827	5.087e-93	314.0	COG2041@1|root,COG2041@2|Bacteria,1G169@1117|Cyanobacteria,1GZD5@1129|Synechococcus	1117|Cyanobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158397_k127_4804120_5	1123279.ATUS01000001_gene761	3.111e-08	57.0	COG2356@1|root,COG2356@2|Bacteria,1PJJC@1224|Proteobacteria,1TI1Q@1236|Gammaproteobacteria,1JAK5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4804120_6	1307436.PBF_17759	5.96e-06	58.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
SRR25158397_k127_4804120_0	1122182.KB903833_gene5566	8.032e-225	724.0	COG3409@1|root,COG3409@2|Bacteria,2H4NG@201174|Actinobacteria	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_481873_0	880073.Calab_0813	6.011e-122	419.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
SRR25158397_k127_481873_1	240015.ACP_1819	5.784e-50	188.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158397_k127_481873_2	1156935.QWE_11336	2.653e-23	107.0	COG2865@1|root,COG2865@2|Bacteria	2|Bacteria	-	-	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SRR25158397_k127_4833219_5	1187851.A33M_2094	8.246e-34	151.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,2U4TR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
SRR25158397_k127_4833219_1	765913.ThidrDRAFT_0679	3.854e-73	258.0	COG3303@1|root,COG3303@2|Bacteria,1QXZC@1224|Proteobacteria,1T59J@1236|Gammaproteobacteria,1WXKQ@135613|Chromatiales	135613|Chromatiales	P	PFAM Doubled CXXCH motif	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SRR25158397_k127_4833219_7	1121448.DGI_1698	4.822e-11	71.0	2E17X@1|root,32WNJ@2|Bacteria,1N3GY@1224|Proteobacteria,42TVS@68525|delta/epsilon subdivisions,2WQQD@28221|Deltaproteobacteria,2MCN4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	tmcA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
SRR25158397_k127_4833219_9	273677.BW34_01161	4.891e-06	55.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria,4FNRD@85023|Microbacteriaceae	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158397_k127_4833219_3	1267533.KB906735_gene4697	1.528e-47	188.0	2DKZK@1|root,310GY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
SRR25158397_k127_4833219_8	1449065.JMLL01000010_gene1506	2.102e-07	63.0	2DE5Q@1|root,2ZKM4@2|Bacteria,1RCVX@1224|Proteobacteria,2U6G7@28211|Alphaproteobacteria,43MK8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
SRR25158397_k127_4833219_4	1089550.ATTH01000001_gene1642	4.813e-38	147.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1FINF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158397_k127_4833219_2	1184267.A11Q_1018	1.67e-50	198.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2MTBA@213481|Bdellovibrionales,2WM41@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158397_k127_4833219_0	1340493.JNIF01000003_gene1371	1.132e-82	286.0	COG1741@1|root,COG1741@2|Bacteria,3Y831@57723|Acidobacteria	57723|Acidobacteria	S	Pirin C-terminal cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
SRR25158397_k127_4833219_6	1131814.JAFO01000001_gene626	1.903e-30	129.0	2E7W0@1|root,332AS@2|Bacteria,1MXHI@1224|Proteobacteria,2U4WI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4834431_16	1043493.BBLU01000014_gene1319	0.0001238	49.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158397_k127_4834431_0	1123257.AUFV01000009_gene2309	1.201e-99	336.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1X5AX@135614|Xanthomonadales	135614|Xanthomonadales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158397_k127_4834431_15	1298867.AUES01000017_gene4043	1.349e-05	55.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1MWIC@1224|Proteobacteria,2TRIA@28211|Alphaproteobacteria,3JS62@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR_2
SRR25158397_k127_4834431_2	861299.J421_0293	2.2e-64	232.0	COG1226@1|root,2ZCE6@2|Bacteria	2|Bacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
SRR25158397_k127_4834431_9	861299.J421_0967	1.807e-16	85.0	2C12A@1|root,33B7C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4834431_6	861299.J421_0966	3.064e-26	109.0	2E40T@1|root,32YXK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4834431_14	1380391.JIAS01000011_gene5401	6.943e-07	58.0	COG3682@1|root,COG3682@2|Bacteria,1N6UP@1224|Proteobacteria,2UJ72@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4834431_11	1123487.KB892863_gene1861	2.864e-11	72.0	COG1846@1|root,COG1846@2|Bacteria,1PW9W@1224|Proteobacteria,2VUDE@28216|Betaproteobacteria,2KXDT@206389|Rhodocyclales	206389|Rhodocyclales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158397_k127_4834431_1	1201288.M900_0348	5.543e-65	244.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2MU2J@213481|Bdellovibrionales,2WKR4@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,Voltage_CLC
SRR25158397_k127_4834431_8	525903.Taci_1650	2.8e-20	100.0	COG2998@1|root,COG2998@2|Bacteria,3TA7W@508458|Synergistetes	508458|Synergistetes	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
SRR25158397_k127_4834431_3	234267.Acid_5304	2.383e-45	173.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158397_k127_4834431_4	1283300.ATXB01000002_gene2888	9.024e-42	168.0	2DP87@1|root,330Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4834431_5	926562.Oweho_2291	5.776e-29	133.0	COG2931@1|root,COG4222@1|root,COG2931@2|Bacteria,COG4222@2|Bacteria,4NKF1@976|Bacteroidetes,1II60@117743|Flavobacteriia,2PBH9@246874|Cryomorphaceae	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
SRR25158397_k127_4834431_7	1444309.JAQG01000100_gene4742	5.872e-23	107.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,274A1@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158397_k127_4834431_12	297246.lpp2502	2.177e-07	61.0	COG3755@1|root,COG3755@2|Bacteria,1NJ7S@1224|Proteobacteria,1SP8U@1236|Gammaproteobacteria,1JFZU@118969|Legionellales	118969|Legionellales	S	Pfam:DUF1311	-	-	-	-	-	-	-	-	-	-	-	-	LprI
SRR25158397_k127_483455_4	1255043.TVNIR_2826	1.81e-29	134.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1SYT9@1236|Gammaproteobacteria,1X25R@135613|Chromatiales	135613|Chromatiales	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158397_k127_483455_5	383372.Rcas_1851	1.712e-23	112.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158397_k127_483455_0	357808.RoseRS_2562	4.931e-179	594.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158397_k127_483455_1	1242864.D187_008909	1.26e-156	518.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158397_k127_483455_3	614083.AWQR01000031_gene2686	6.966e-30	136.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2VVJM@28216|Betaproteobacteria,4AEUN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158397_k127_483455_2	861299.J421_6223	1.021e-45	173.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4845550_1	926550.CLDAP_13780	5.776e-73	262.0	COG2311@1|root,COG2311@2|Bacteria,2G8B7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR25158397_k127_4845550_2	760192.Halhy_4332	1.8e-36	162.0	COG1262@1|root,COG1672@1|root,COG3064@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG3064@2|Bacteria,4PN7M@976|Bacteroidetes,1IXXU@117747|Sphingobacteriia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4845550_4	1463857.JOFZ01000001_gene5387	0.000454	52.0	COG1413@1|root,COG1413@2|Bacteria,2IIM7@201174|Actinobacteria	201174|Actinobacteria	C	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TIR_2
SRR25158397_k127_4845550_3	1499967.BAYZ01000076_gene778	1.975e-31	139.0	2EKYY@1|root,33ENF@2|Bacteria	2|Bacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
SRR25158397_k127_4845550_0	502025.Hoch_6444	8.971e-157	518.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158397_k127_4852255_6	452637.Oter_4521	3.359e-58	211.0	COG0702@1|root,COG0702@2|Bacteria,46YBQ@74201|Verrucomicrobia,3K8MJ@414999|Opitutae	414999|Opitutae	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158397_k127_4852255_4	861299.J421_4246	1.831e-87	295.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	nueM	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
SRR25158397_k127_4852255_2	1123508.JH636439_gene1738	1.511e-156	506.0	COG2252@1|root,COG2252@2|Bacteria	2|Bacteria	S	purine nucleobase transmembrane transporter activity	yicO	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158397_k127_4852255_8	1500893.JQNB01000001_gene18	0.0002311	48.0	COG2823@1|root,COG2823@2|Bacteria,1PY9T@1224|Proteobacteria,1T6Y1@1236|Gammaproteobacteria,1X8DX@135614|Xanthomonadales	135614|Xanthomonadales	S	periplasmic or secreted lipoprotein	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158397_k127_4852255_3	234267.Acid_2024	9.258e-95	317.0	COG1801@1|root,COG1801@2|Bacteria,3Y2WS@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158397_k127_4852255_5	637390.AFOH01000120_gene560	4.28e-64	230.0	COG1715@1|root,COG1715@2|Bacteria,1R4NQ@1224|Proteobacteria,1SEK9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
SRR25158397_k127_4852255_0	1038859.AXAU01000031_gene4157	4.626e-241	758.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3JTRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158397_k127_4852255_1	246197.MXAN_6145	7.672e-241	799.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	1224|Proteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36
SRR25158397_k127_4852255_9	1463885.KL578463_gene3685	0.0003272	55.0	COG2373@1|root,COG2374@1|root,COG2373@2|Bacteria,COG2374@2|Bacteria,2IAQ8@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Gly_rich
SRR25158397_k127_4852255_7	1121946.AUAX01000003_gene1729	1.131e-07	66.0	COG0726@1|root,COG0726@2|Bacteria,2GNF1@201174|Actinobacteria,4DBWD@85008|Micromonosporales	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4867263_2	1297742.A176_00835	4.409e-18	98.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,42QZQ@68525|delta/epsilon subdivisions,2WMV8@28221|Deltaproteobacteria,2YVB0@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158397_k127_4867263_3	1173028.ANKO01000016_gene46	4.082e-10	66.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG4251@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158397_k127_4867263_1	264462.Bd1027	9.963e-58	224.0	COG2605@1|root,COG2605@2|Bacteria,1Q1GI@1224|Proteobacteria,42TJZ@68525|delta/epsilon subdivisions,2MT41@213481|Bdellovibrionales,2WQNP@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158397_k127_4867263_0	1121439.dsat_1000	4.374e-76	271.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158397_k127_4873445_1	632518.Calow_0861	6.194e-53	206.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_4873445_3	1499967.BAYZ01000184_gene4554	4.271e-05	57.0	COG4995@1|root,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158397_k127_4873445_0	671143.DAMO_2095	1.034e-120	413.0	COG0744@1|root,COG0744@2|Bacteria,2NNMB@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158397_k127_4873445_2	1380355.JNIJ01000004_gene2769	6.158e-15	87.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Laminin_G_3,PPC
SRR25158397_k127_4877350_4	1122194.AUHU01000005_gene880	0.0001088	45.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,464VM@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158397_k127_4877350_2	278963.ATWD01000001_gene2834	4.941e-41	159.0	COG0521@1|root,COG0521@2|Bacteria,3Y504@57723|Acidobacteria,2JJI8@204432|Acidobacteriia	204432|Acidobacteriia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158397_k127_4877350_0	290397.Adeh_2411	3.741e-125	412.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158397_k127_4877350_1	378806.STAUR_4654	4.12e-92	317.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158397_k127_4877350_3	420246.GTNG_0711	2.42e-36	153.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1WFYU@129337|Geobacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158397_k127_4884748_1	448385.sce9074	1.274e-87	300.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria	1224|Proteobacteria	S	ABC transporter, (ATP-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158397_k127_4884748_2	448385.sce9075	6.51e-81	289.0	COG1668@1|root,COG1668@2|Bacteria,1R62N@1224|Proteobacteria	1224|Proteobacteria	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158397_k127_4884748_0	861299.J421_2707	5.025e-154	520.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158397_k127_4884748_3	765869.BDW_06800	2.567e-57	227.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2MSRD@213481|Bdellovibrionales,2WINP@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158397_k127_4904785_8	880071.Fleli_0802	3.497e-06	51.0	2CRMH@1|root,32SPB@2|Bacteria,4NTBB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569,DinB_2
SRR25158397_k127_4904785_1	1501230.ET33_16865	4.95e-70	250.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,26QWG@186822|Paenibacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158397_k127_4904785_7	751994.AGIG01000028_gene1805	1.47e-08	63.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	rhodanese-related sulfurtransferase	yibN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_4904785_4	163908.KB235896_gene2187	2.767e-15	87.0	COG1651@1|root,COG1651@2|Bacteria,1G379@1117|Cyanobacteria,1HMDE@1161|Nostocales	1117|Cyanobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
SRR25158397_k127_4904785_5	1280953.HOC_14108	6.026e-14	75.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,2UB31@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
SRR25158397_k127_4904785_6	1235802.C823_06282	5.627e-12	69.0	COG2929@1|root,COG2929@2|Bacteria,1VAQB@1239|Firmicutes,24N2P@186801|Clostridia,25XZH@186806|Eubacteriaceae	186801|Clostridia	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
SRR25158397_k127_4904785_3	316067.Geob_0705	7.096e-25	114.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4904785_2	1547437.LL06_11615	6.278e-65	239.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,43ICR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158397_k127_4904785_0	204669.Acid345_3335	1.386e-114	390.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158397_k127_4904785_9	1159870.KB907784_gene3357	0.0001502	51.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,3T868@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
SRR25158397_k127_4906111_0	1297742.A176_04476	2.667e-08	67.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_4906111_1	324602.Caur_2531	1.567e-05	53.0	COG0793@1|root,COG0793@2|Bacteria,2GBRW@200795|Chloroflexi,376BR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41,Tricorn_C1
SRR25158397_k127_4909175_7	338966.Ppro_2752	1.444e-35	150.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,43VBU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4909175_9	1464048.JNZS01000001_gene40	2.106e-12	78.0	COG1075@1|root,COG1075@2|Bacteria,2I090@201174|Actinobacteria,4DG74@85008|Micromonosporales	201174|Actinobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
SRR25158397_k127_4909175_3	1382359.JIAL01000001_gene2644	2.452e-71	253.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158397_k127_4909175_10	404589.Anae109_0072	1.187e-06	58.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR25158397_k127_4909175_11	1340493.JNIF01000004_gene1097	3.985e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria	1340493.JNIF01000004_gene1097|-	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4909175_5	1242864.D187_004746	8.097e-55	220.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158397_k127_4909175_6	1121946.AUAX01000031_gene977	1.146e-45	176.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4D9SI@85008|Micromonosporales	201174|Actinobacteria	I	Diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRR25158397_k127_4909175_2	1144275.COCOR_03463	6.804e-93	321.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158397_k127_4909175_8	215803.DB30_5890	1.009e-17	89.0	COG1451@1|root,COG1451@2|Bacteria,1P1X1@1224|Proteobacteria,4314C@68525|delta/epsilon subdivisions,2WX53@28221|Deltaproteobacteria,2YY4V@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4909175_12	1094553.MCS_01230	0.0001541	48.0	COG4575@1|root,COG4575@2|Bacteria,1NGZU@1224|Proteobacteria,2UJGB@28211|Alphaproteobacteria,48U7S@772|Bartonellaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
SRR25158397_k127_4909175_4	768706.Desor_4174	5.512e-59	217.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_4909175_0	1131269.AQVV01000009_gene1116	6.112e-130	450.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_4909175_1	935863.AWZR01000007_gene127	4.384e-94	327.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1X452@135614|Xanthomonadales	135614|Xanthomonadales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158397_k127_4924407_7	204669.Acid345_0767	3.322e-38	147.0	COG0509@1|root,COG0509@2|Bacteria,3Y7RS@57723|Acidobacteria	57723|Acidobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
SRR25158397_k127_4924407_6	204669.Acid345_2605	5.051e-43	180.0	COG1913@1|root,COG1913@2|Bacteria,3Y880@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
SRR25158397_k127_4924407_2	880072.Desac_0992	5.962e-118	412.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFQ@28221|Deltaproteobacteria,2MRGA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_4924407_0	204669.Acid345_2603	1.199e-156	510.0	COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria,2JP3M@204432|Acidobacteriia	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158397_k127_4924407_1	234267.Acid_4205	3.356e-126	419.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158397_k127_4924407_4	204669.Acid345_2601	1.079e-84	305.0	COG0437@1|root,COG0437@2|Bacteria,3Y5RE@57723|Acidobacteria,2JKSV@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	DmsC,Fer4_11
SRR25158397_k127_4924407_11	204669.Acid345_0759	9.878e-06	53.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
SRR25158397_k127_4924407_8	883126.HMPREF9710_01884	4.509e-25	114.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158397_k127_4924407_10	1415775.U729_1435	7.273e-18	96.0	COG5164@1|root,COG5164@2|Bacteria,1VFKD@1239|Firmicutes,24Z10@186801|Clostridia,36UP7@31979|Clostridiaceae	186801|Clostridia	K	Collagen triple helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	C1q,Collagen
SRR25158397_k127_4924407_5	1500306.JQLA01000037_gene135	8.717e-66	231.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2U6QG@28211|Alphaproteobacteria,4BBG9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158397_k127_4924407_9	331678.Cphamn1_0814	9.554e-24	107.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRR25158397_k127_4924407_3	1288826.MSNKSG1_01983	4.46e-111	371.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S726@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158397_k127_4928189_1	1237149.C900_03217	8.885e-111	382.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_4928189_4	1120917.AQXM01000051_gene292	7.602e-29	133.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,1WARJ@1268|Micrococcaceae	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158397_k127_4928189_2	391937.NA2_17047	4.456e-67	235.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,2TUBN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	DeAcetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158397_k127_4928189_0	443255.SCLAV_p0535	3.933e-112	374.0	2F3XQ@1|root,33WPT@2|Bacteria	2|Bacteria	S	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158397_k127_4928189_3	468059.AUHA01000002_gene687	2.834e-58	212.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IS0X@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158397_k127_4928189_5	1499967.BAYZ01000091_gene3428	3.071e-14	78.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
SRR25158397_k127_4930257_4	1267535.KB906767_gene2239	1.773e-08	64.0	2B6R1@1|root,31ZPU@2|Bacteria,3Y4VP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4930257_2	234267.Acid_4300	2.004e-49	182.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158397_k127_4930257_3	204669.Acid345_4105	1.844e-33	133.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158397_k127_4930257_1	1382359.JIAL01000001_gene2813	1.192e-64	234.0	COG0616@1|root,COG0616@2|Bacteria,3Y3M1@57723|Acidobacteria,2JI8A@204432|Acidobacteriia	204432|Acidobacteriia	OU	PFAM peptidase S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158397_k127_4930257_0	1499967.BAYZ01000095_gene4092	9.766e-143	462.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Cytidylate_kin,LYTB,S1
SRR25158397_k127_4934480_0	1123368.AUIS01000019_gene1214	1.725e-176	584.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158397_k127_4934480_1	1121920.AUAU01000002_gene1987	1.32e-56	201.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158397_k127_4934480_2	234267.Acid_2235	6.836e-30	123.0	COG1970@1|root,COG1970@2|Bacteria,3Y58F@57723|Acidobacteria	57723|Acidobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158397_k127_4934480_3	1267535.KB906767_gene784	1.232e-25	113.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_4941240_3	10228.TriadP56187	6.043e-29	119.0	2CDB0@1|root,2QUGZ@2759|Eukaryota,39UAM@33154|Opisthokonta,3BJ8Z@33208|Metazoa	33208|Metazoa	C	thyroxine 5'-deiodinase activity	DIO1	GO:0003674,GO:0003824,GO:0004800,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008430,GO:0009987,GO:0010817,GO:0016020,GO:0016491,GO:0018958,GO:0042403,GO:0042445,GO:0044237,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360,GO:1901564,GO:1901615	1.21.99.4	ko:K01562	ko04919,map04919	-	-	-	ko00000,ko00001,ko01000	-	-	-	T4_deiodinase
SRR25158397_k127_4941240_2	502025.Hoch_4605	1.425e-33	140.0	2FCEE@1|root,344HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR25158397_k127_4941240_1	204669.Acid345_1474	2.601e-154	499.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158397_k127_4941240_0	1198452.Jab_1c04630	0.0	1355.0	COG4630@1|root,COG4631@1|root,COG4630@2|Bacteria,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158397_k127_4971864_3	1280696.ATVY01000026_gene130	5.473e-53	193.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,4BX2C@830|Butyrivibrio	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158397_k127_4971864_2	234267.Acid_5118	4.779e-71	247.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158397_k127_4971864_4	1267535.KB906767_gene2705	2.515e-50	180.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158397_k127_4971864_1	338966.Ppro_0678	7.009e-211	659.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,43U3Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158397_k127_4971864_0	635013.TherJR_0293	1.082e-212	670.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2600F@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158397_k127_4980129_6	1288963.ADIS_4682	1.312e-32	129.0	COG3832@1|root,COG3832@2|Bacteria,4NTMD@976|Bacteroidetes,47SP5@768503|Cytophagia	976|Bacteroidetes	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158397_k127_4980129_1	765911.Thivi_2111	1.654e-159	537.0	COG2197@1|root,COG5001@1|root,COG2197@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,SBP_bac_3
SRR25158397_k127_4980129_4	35754.JNYJ01000008_gene3186	3.032e-54	206.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,4DI9G@85008|Micromonosporales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,PAS_2,PAS_4,PHY
SRR25158397_k127_4980129_8	323261.Noc_1758	1.613e-22	101.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WW1B@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,Response_reg
SRR25158397_k127_4980129_2	404380.Gbem_0748	3.516e-90	312.0	COG2201@1|root,COG2201@2|Bacteria,1R5IM@1224|Proteobacteria,42Q4X@68525|delta/epsilon subdivisions,2WMDB@28221|Deltaproteobacteria,43T38@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB40H-1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158397_k127_4980129_3	443143.GM18_3601	2.395e-78	291.0	COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
SRR25158397_k127_4980129_5	443144.GM21_0765	2.5e-44	165.0	COG2199@1|root,COG3706@2|Bacteria,1MZZV@1224|Proteobacteria,42UXH@68525|delta/epsilon subdivisions,2WVP3@28221|Deltaproteobacteria,43SMM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158397_k127_4980129_9	379066.GAU_3482	1.848e-12	81.0	2EN4X@1|root,33FSY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4980129_0	243090.RB5969	1.475e-204	670.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158397_k127_4980129_7	292459.STH3142	2.242e-32	131.0	COG4231@1|root,COG4231@2|Bacteria,1VIY6@1239|Firmicutes,24PDQ@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158397_k127_4980129_10	1201290.M902_1290	0.0005146	47.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HEAT_2
SRR25158397_k127_4981951_2	234267.Acid_7868	5.534e-74	260.0	COG1230@1|root,COG1230@2|Bacteria,3Y32W@57723|Acidobacteria	57723|Acidobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158397_k127_4981951_4	1089548.KI783301_gene151	1.057e-48	179.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3WE9G@539002|Bacillales incertae sedis	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158397_k127_4981951_0	868864.Dester_0424	5.523e-137	450.0	COG0151@1|root,COG0151@2|Bacteria,2G3J3@200783|Aquificae	200783|Aquificae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158397_k127_4981951_5	1379698.RBG1_1C00001G1702	1.299e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158397_k127_4981951_6	1437824.BN940_09271	0.0007951	50.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria,3T2T4@506|Alcaligenaceae	28216|Betaproteobacteria	NU	general secretion pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
SRR25158397_k127_4981951_1	861299.J421_2444	8.409e-121	407.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1ZTG4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5
SRR25158397_k127_4981951_3	1026882.MAMP_01697	5.264e-49	183.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,4603F@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158397_k127_4984815_3	926554.KI912668_gene5117	2.042e-35	156.0	COG0438@1|root,COG0438@2|Bacteria,1WK9I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4984815_1	1121377.KB906417_gene3827	3.55e-64	250.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4984815_6	573063.Metin_0259	5.465e-07	61.0	COG2456@1|root,arCOG05092@2157|Archaea,2XZCE@28890|Euryarchaeota,23R5T@183939|Methanococci	183939|Methanococci	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SRR25158397_k127_4984815_2	314230.DSM3645_19723	1.741e-57	209.0	COG1215@1|root,COG1215@2|Bacteria,2J52E@203682|Planctomycetes	203682|Planctomycetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_4984815_5	870187.Thini_1261	7.707e-08	64.0	2DBRU@1|root,2ZANA@2|Bacteria,1NIAW@1224|Proteobacteria,1SGWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_4984815_0	404589.Anae109_1852	1.362e-64	241.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase,HATPase_c,HisKA,Response_reg
SRR25158397_k127_4984815_4	41431.PCC8801_3359	7.197e-27	113.0	COG0438@1|root,COG0438@2|Bacteria,1G1WR@1117|Cyanobacteria,3KIHB@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase group 1	-	-	-	ko:K12993	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_4991847_0	867845.KI911784_gene1260	2.144e-104	367.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
SRR25158397_k127_4991847_1	926554.KI912657_gene4365	3.531e-69	244.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K06212,ko:K21990,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.4	-	-	Form_Nir_trans
SRR25158397_k127_4991847_5	622312.ROSEINA2194_02937	2.892e-14	85.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_4991847_3	1242864.D187_010224	5.477e-61	218.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria	1224|Proteobacteria	L	Pfam 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158397_k127_4991847_4	1254432.SCE1572_18490	3.523e-53	204.0	COG3386@1|root,COG3386@2|Bacteria,1QY38@1224|Proteobacteria,43CUW@68525|delta/epsilon subdivisions,2X82P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158397_k127_4991847_2	1287276.X752_22205	7.87e-67	233.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
SRR25158397_k127_5001554_1	29581.BW37_04779	1.514e-98	342.0	COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5001554_8	56780.SYN_01772	2.874e-09	70.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MQHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158397_k127_5001554_6	682795.AciX8_0882	5.122e-21	108.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria,2JKFK@204432|Acidobacteriia	204432|Acidobacteriia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158397_k127_5001554_5	382464.ABSI01000013_gene1538	7.036e-33	141.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158397_k127_5001554_9	234267.Acid_0699	1.757e-06	61.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_5001554_2	1184267.A11Q_1101	3.747e-58	224.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2MT84@213481|Bdellovibrionales,2WRY5@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158397_k127_5001554_12	76114.ebD35	9.515e-05	50.0	COG1396@1|root,COG1396@2|Bacteria,1NIMT@1224|Proteobacteria,2VY8C@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158397_k127_5001554_3	1297865.APJD01000017_gene4213	1.474e-41	167.0	COG4487@1|root,COG4487@2|Bacteria,1MWNT@1224|Proteobacteria,2TT7A@28211|Alphaproteobacteria,3JT1Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2130)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
SRR25158397_k127_5001554_0	348824.LPU83_pLPU83a_0048	4.787e-116	384.0	29X5E@1|root,30IUE@2|Bacteria,1NS25@1224|Proteobacteria,2UPR4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158397_k127_5001554_7	1265502.KB905933_gene2038	2.55e-20	107.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,2VMI9@28216|Betaproteobacteria,4ACCB@80864|Comamonadaceae	28216|Betaproteobacteria	P	Tonb-dependent hemoglobin transferrin lactoferrin family receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_5001554_4	526225.Gobs_2511	1.28e-38	152.0	COG0398@1|root,COG0398@2|Bacteria,2GYCV@201174|Actinobacteria	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_5034885_2	234267.Acid_1652	7.168e-109	386.0	COG0457@1|root,COG4995@1|root,COG5293@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,COG5293@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158397_k127_5034885_11	452637.Oter_4613	7.96e-05	53.0	2EHJS@1|root,33BBN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5034885_10	590998.Celf_3038	1.658e-13	83.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
SRR25158397_k127_5034885_7	1379698.RBG1_1C00001G0468	1.524e-32	132.0	COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria	2|Bacteria	S	DinB family	yrdA	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158397_k127_5034885_4	929703.KE386491_gene3858	2.924e-57	223.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158397_k127_5034885_1	404589.Anae109_3042	2.176e-297	926.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria,1MU1B@1224|Proteobacteria,42NS2@68525|delta/epsilon subdivisions,2WMA0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,NrfD
SRR25158397_k127_5034885_0	404589.Anae109_3043	0.0	1172.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158397_k127_5034885_3	404589.Anae109_3044	9.255e-70	245.0	COG0243@1|root,COG0243@2|Bacteria,1MWPS@1224|Proteobacteria,42QIW@68525|delta/epsilon subdivisions,2WJPY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Molybdopterin oxidoreductase Fe4S4 region	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin
SRR25158397_k127_5034885_8	861299.J421_0577	2.145e-23	113.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1ZV5J@142182|Gemmatimonadetes	2|Bacteria	O	Subtilase family	-	-	3.2.1.14,3.4.21.50	ko:K01183,ko:K01337,ko:K14645	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH18	-	Inhibitor_I9,PKD,PPC,P_proprotein,Peptidase_M14,Peptidase_S8
SRR25158397_k127_5034885_6	1379698.RBG1_1C00001G0743	3.189e-36	142.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
SRR25158397_k127_5034885_9	1189612.A33Q_3191	1.336e-15	81.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,47QV5@768503|Cytophagia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
SRR25158397_k127_5052136_0	886293.Sinac_6462	2.235e-163	518.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158397_k127_5052136_7	1121017.AUFG01000039_gene910	7.005e-07	63.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158397_k127_5052136_5	1254432.SCE1572_00345	2.501e-12	80.0	2EI76@1|root,33BYI@2|Bacteria,1RBW7@1224|Proteobacteria,42QZD@68525|delta/epsilon subdivisions,2WN6J@28221|Deltaproteobacteria,2YXMN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5052136_3	768710.DesyoDRAFT_3286	6.25e-25	116.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158397_k127_5052136_2	1144275.COCOR_03823	1.703e-30	136.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5052136_4	330214.NIDE1727	4.347e-13	78.0	COG0484@1|root,COG0484@2|Bacteria,3J0A7@40117|Nitrospirae	40117|Nitrospirae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158397_k127_5052136_1	404589.Anae109_3817	3.296e-68	239.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158397_k127_5052136_8	265072.Mfla_0384	0.0001344	46.0	COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,2VUXZ@28216|Betaproteobacteria,2KN56@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158397_k127_5052136_6	1121920.AUAU01000009_gene1941	3.162e-07	63.0	COG2206@1|root,COG2206@2|Bacteria,3Y52R@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5053588_2	756272.Plabr_3360	5.002e-143	470.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158397_k127_5053588_9	1265505.ATUG01000003_gene315	1.13e-17	90.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2WPKF@28221|Deltaproteobacteria,2MJSC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158397_k127_5053588_4	1123511.KB905871_gene64	1.643e-91	308.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H331@909932|Negativicutes	909932|Negativicutes	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158397_k127_5053588_6	269799.Gmet_3412	2.261e-69	247.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43U5F@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ParB domain protein nuclease	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158397_k127_5053588_7	439235.Dalk_3632	1.712e-23	112.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MM26@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158397_k127_5053588_11	338963.Pcar_1987	8.819e-17	89.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158397_k127_5053588_13	1122247.C731_3119	0.0001038	54.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,238GJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iNJ661.Rv1306	ATP-synt_B
SRR25158397_k127_5053588_12	1121918.ARWE01000001_gene3516	1.634e-10	72.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,43SQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase B/B' CF(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158397_k127_5053588_10	518766.Rmar_0314	1.946e-17	89.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1FJFS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158397_k127_5053588_1	671143.DAMO_2962	4.672e-229	719.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158397_k127_5053588_5	234267.Acid_0464	5.897e-82	281.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158397_k127_5053588_0	204669.Acid345_4332	4.62e-239	747.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158397_k127_5053588_8	1125863.JAFN01000001_gene2670	2.404e-23	104.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158397_k127_5053588_14	76869.PputGB1_0020	0.0003797	52.0	COG0642@1|root,COG0642@2|Bacteria,1QTVA@1224|Proteobacteria,1T1IE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	member of a two-component regulatory system	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
SRR25158397_k127_5053588_3	76114.ebA6902	2.907e-114	379.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KU97@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_5053743_4	290397.Adeh_4303	1.926e-57	210.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158397_k127_5053743_12	1040983.AXAE01000005_gene1795	2.74e-11	73.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1R3SH@1224|Proteobacteria,2U1ZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Peptidase_C14,TPR_10,TPR_8
SRR25158397_k127_5053743_15	1278073.MYSTI_02737	8.93e-05	47.0	2BQRB@1|root,32JMY@2|Bacteria,1PDGZ@1224|Proteobacteria,435GN@68525|delta/epsilon subdivisions,2WZU3@28221|Deltaproteobacteria,2Z2RN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5053743_11	215803.DB30_3743	2.827e-14	73.0	2ANK2@1|root,31DJ5@2|Bacteria,1QAV5@1224|Proteobacteria,435BD@68525|delta/epsilon subdivisions,2WZNS@28221|Deltaproteobacteria,2Z2FM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5053743_2	1125863.JAFN01000001_gene2041	9.998e-87	304.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158397_k127_5053743_10	1033734.CAET01000041_gene380	8.668e-17	94.0	COG2247@1|root,COG4733@1|root,COG2247@2|Bacteria,COG4733@2|Bacteria,1UIEV@1239|Firmicutes,4ISVE@91061|Bacilli,1ZS75@1386|Bacillus	91061|Bacilli	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
SRR25158397_k127_5053743_6	861299.J421_3028	1.001e-39	166.0	28M10@1|root,301VW@2|Bacteria,1ZT4C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
SRR25158397_k127_5053743_9	715226.ABI_09240	6.97e-24	109.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,2UFFG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRR25158397_k127_5053743_13	743720.Psefu_1725	4.235e-07	57.0	2E3S2@1|root,32YPN@2|Bacteria,1NDK1@1224|Proteobacteria,1SEFA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5053743_0	1005048.CFU_3179	8.153e-207	666.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,2VP2M@28216|Betaproteobacteria,476SV@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158397_k127_5053743_7	861299.J421_4501	5.049e-38	154.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4501|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5053743_5	366649.XFF4834R_chr12820	4.44e-46	185.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158397_k127_5053743_1	452637.Oter_1629	2.124e-120	394.0	COG0266@1|root,COG0266@2|Bacteria	2|Bacteria	L	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158397_k127_5053743_8	1267535.KB906767_gene1533	5.607e-32	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K07263	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_5053743_3	1267535.KB906767_gene1535	4.709e-82	292.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158397_k127_5053743_14	1347086.CCBA010000034_gene2741	1.02e-05	55.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
SRR25158397_k127_5055812_6	483219.LILAB_27460	3.972e-07	54.0	COG3239@1|root,COG3239@2|Bacteria,1R3Y2@1224|Proteobacteria,434KY@68525|delta/epsilon subdivisions,2WYYD@28221|Deltaproteobacteria,2Z0X8@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158397_k127_5055812_2	1144275.COCOR_02776	1.309e-44	181.0	COG4875@1|root,COG4875@2|Bacteria	2|Bacteria	IQ	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	CaMKII_AD,DUF4440,SnoaL_2,SnoaL_3
SRR25158397_k127_5055812_0	483219.LILAB_27465	1.74e-60	225.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,437H0@68525|delta/epsilon subdivisions,2X2QC@28221|Deltaproteobacteria,2YXMK@29|Myxococcales	28221|Deltaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158397_k127_5055812_4	1300345.LF41_1012	1.091e-36	154.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_2,Abhydrolase_4,Esterase
SRR25158397_k127_5055812_3	518766.Rmar_0611	8.692e-37	145.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158397_k127_5055812_1	1121272.KB903290_gene4747	3.642e-60	218.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5055812_5	65093.PCC7418_0978	1.282e-25	111.0	COG0475@1|root,COG0475@2|Bacteria,1G03Z@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Sodium hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158397_k127_5057181_4	1297742.A176_05669	1.646e-44	166.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158397_k127_5057181_0	502025.Hoch_2041	6.063e-97	348.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_5057181_1	1121920.AUAU01000002_gene2046	1.061e-63	228.0	COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
SRR25158397_k127_5057181_3	1085623.GNIT_1368	3.393e-47	196.0	COG2931@1|root,COG2931@2|Bacteria,1R269@1224|Proteobacteria,1S1GT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158397_k127_5057181_5	1082932.ATCR1_03369	3.248e-42	157.0	COG0346@1|root,COG0346@2|Bacteria,1N15G@1224|Proteobacteria,2UCYE@28211|Alphaproteobacteria,4BEKA@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_5057181_2	314230.DSM3645_06149	2.23e-50	191.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_5057181_6	1128421.JAGA01000002_gene945	4.971e-35	138.0	COG1028@1|root,COG1028@2|Bacteria	1128421.JAGA01000002_gene945|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5063596_9	331678.Cphamn1_0845	1.067e-42	168.0	COG1947@1|root,COG1947@2|Bacteria,1FDN3@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158397_k127_5063596_1	1247726.MIM_c34140	3.59e-163	533.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNB8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158397_k127_5063596_2	404589.Anae109_3957	1.104e-153	497.0	COG0312@1|root,COG0312@2|Bacteria,1RBJZ@1224|Proteobacteria,42YBE@68525|delta/epsilon subdivisions,2WUP7@28221|Deltaproteobacteria,2YZ4Y@29|Myxococcales	28221|Deltaproteobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158397_k127_5063596_0	1242864.D187_006073	7.29e-217	693.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42Y66@68525|delta/epsilon subdivisions,2WU83@28221|Deltaproteobacteria,2YX71@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158397_k127_5063596_3	1235803.C825_05279	2.572e-90	303.0	COG1131@1|root,COG1131@2|Bacteria,4NE3Z@976|Bacteroidetes,2FR55@200643|Bacteroidia,22ZR5@171551|Porphyromonadaceae	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158397_k127_5063596_6	1047013.AQSP01000131_gene1819	5.794e-63	237.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
SRR25158397_k127_5063596_15	1089552.KI911559_gene3709	9.65e-09	68.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,2JQFK@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158397_k127_5063596_17	381666.H16_B2118	7.609e-07	61.0	COG1277@1|root,COG1277@2|Bacteria,1MW7Y@1224|Proteobacteria,2VPDT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3526)	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,DUF3526
SRR25158397_k127_5063596_16	991905.SL003B_0561	3.097e-08	67.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2U10D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
SRR25158397_k127_5063596_12	935836.JAEL01000017_gene797	2.057e-23	112.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,1ZBKH@1386|Bacillus	91061|Bacilli	S	ABC transporter (permease)	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158397_k127_5063596_13	573061.Clocel_0457	1.586e-22	108.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,24A3T@186801|Clostridia,36E7Y@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158397_k127_5063596_4	591157.SSLG_04344	3.891e-77	271.0	COG4586@1|root,COG4586@2|Bacteria,2GKSX@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,ArgK
SRR25158397_k127_5063596_14	391165.GbCGDNIH1_1926	3.225e-21	110.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JR0C@204441|Rhodospirillales	204441|Rhodospirillales	S	peptidyl-tyrosine modification	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_5063596_10	588581.Cpap_1000	6.035e-40	171.0	COG0535@1|root,COG0535@2|Bacteria,1VWDT@1239|Firmicutes	1239|Firmicutes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_5063596_11	588581.Cpap_1000	4.084e-29	132.0	COG0535@1|root,COG0535@2|Bacteria,1VWDT@1239|Firmicutes	1239|Firmicutes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_5063596_8	588581.Cpap_1000	7.899e-45	181.0	COG0535@1|root,COG0535@2|Bacteria,1VWDT@1239|Firmicutes	1239|Firmicutes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158397_k127_5063596_5	177437.HRM2_05760	1.852e-68	250.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFQ@28221|Deltaproteobacteria,2MIXP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_5063596_7	1121920.AUAU01000004_gene861	2.242e-59	218.0	COG1309@1|root,COG1309@2|Bacteria,3Y5K3@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158397_k127_5063596_18	1463853.JOHW01000007_gene4775	8.879e-07	56.0	COG0824@1|root,COG0824@2|Bacteria,2IFZ9@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158397_k127_5076010_1	649349.Lbys_1072	7.864e-52	190.0	COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_5076010_0	1144275.COCOR_03721	6.003e-167	574.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2YUDK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
SRR25158397_k127_5076018_0	292459.STH2591	9.425e-72	251.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158397_k127_5076018_1	1340493.JNIF01000003_gene2985	1.866e-41	161.0	COG0204@1|root,COG0204@2|Bacteria,3Y4EM@57723|Acidobacteria	57723|Acidobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158397_k127_5076018_2	67373.JOBF01000014_gene4599	4.556e-25	115.0	COG1917@1|root,COG1917@2|Bacteria,2IKKG@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
SRR25158397_k127_5076018_3	1449063.JMLS01000011_gene265	2.064e-20	101.0	COG2318@1|root,COG2318@2|Bacteria,1VBVV@1239|Firmicutes,4HNA7@91061|Bacilli,26X21@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_5079795_2	357808.RoseRS_3112	5.389e-20	106.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5079795_1	335543.Sfum_2371	3.694e-28	133.0	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
SRR25158397_k127_5079795_0	1996.JOFO01000028_gene5939	1.203e-55	198.0	2D579@1|root,32TID@2|Bacteria,2IMWE@201174|Actinobacteria,4EK8I@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5097267_1	1267533.KB906733_gene3362	5.1e-96	336.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158397_k127_5097267_2	666681.M301_1923	3.804e-05	53.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VR6Y@28216|Betaproteobacteria,2KKCV@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158397_k127_5097267_0	290397.Adeh_3892	2.821e-293	928.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2YUEP@29|Myxococcales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158397_k127_5105522_0	1198114.AciX9_2492	3.14e-19	106.0	COG4932@1|root,COG4932@2|Bacteria,3Y8E2@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158397_k127_5115255_3	512565.AMIS_22740	0.0004775	50.0	COG2200@1|root,COG4250@1|root,COG2200@2|Bacteria,COG4250@2|Bacteria,2GNSQ@201174|Actinobacteria,4D9GK@85008|Micromonosporales	201174|Actinobacteria	T	Sensory domain in DIguanylate Cyclases and Two-component system	-	-	-	-	-	-	-	-	-	-	-	-	DICT,EAL,GGDEF,PAS_9
SRR25158397_k127_5115255_2	1278073.MYSTI_03701	2.058e-21	98.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	phcR	-	-	ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	HATPase_c,HDOD,Response_reg
SRR25158397_k127_5115255_1	1297742.A176_00265	5.271e-69	265.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3
SRR25158397_k127_5115255_0	667014.Thein_1531	2.195e-109	389.0	COG0462@1|root,COG0462@2|Bacteria,2GGWM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158397_k127_5119046_7	429009.Adeg_1570	1.133e-28	121.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,42FD0@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158397_k127_5119046_1	1278073.MYSTI_06199	1.777e-124	417.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158397_k127_5119046_2	204669.Acid345_3633	3.732e-95	332.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158397_k127_5119046_0	1122929.KB908217_gene273	2.594e-125	411.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158397_k127_5119046_4	338963.Pcar_2204	9.945e-90	312.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,43SC6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mur ligase middle domain	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
SRR25158397_k127_5119046_3	1382359.JIAL01000001_gene1976	4.987e-92	315.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158397_k127_5119046_5	1144275.COCOR_06095	7.105e-83	293.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWWJ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158397_k127_5119046_6	562970.Btus_0663	3.593e-46	172.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,279CH@186823|Alicyclobacillaceae	91061|Bacilli	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158397_k127_5135060_15	309801.trd_A0767	2.947e-33	138.0	COG1268@1|root,COG1268@2|Bacteria,2GBUZ@200795|Chloroflexi,27YWE@189775|Thermomicrobia	189775|Thermomicrobia	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158397_k127_5135060_13	45157.CMO291CT	4.221e-40	171.0	COG0120@1|root,KOG3075@2759|Eukaryota	2759|Eukaryota	G	ribose-5-phosphate isomerase activity	RPI2	GO:0000003,GO:0000271,GO:0003006,GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0007275,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009116,GO:0009119,GO:0009163,GO:0009250,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009719,GO:0009725,GO:0009735,GO:0009791,GO:0009941,GO:0009987,GO:0010033,GO:0010228,GO:0015977,GO:0015979,GO:0016020,GO:0016051,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019253,GO:0019438,GO:0019685,GO:0022414,GO:0030243,GO:0030244,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0032501,GO:0032502,GO:0033692,GO:0034357,GO:0034404,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042455,GO:0042651,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046108,GO:0046109,GO:0046131,GO:0046132,GO:0046134,GO:0046483,GO:0048608,GO:0048731,GO:0048856,GO:0050896,GO:0051273,GO:0051274,GO:0051704,GO:0051707,GO:0055035,GO:0055086,GO:0061458,GO:0071704,GO:0072527,GO:0072528,GO:0080167,GO:0098542,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158397_k127_5135060_3	504832.OCAR_4339	2.684e-87	323.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,3JRHC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158397_k127_5135060_2	370438.PTH_0258	6.766e-90	302.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158397_k127_5135060_22	1101190.ARWB01000001_gene341	2.248e-12	78.0	COG3755@1|root,COG3755@2|Bacteria,1NJ7S@1224|Proteobacteria,2UWNT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pfam:DUF1311	-	-	-	-	-	-	-	-	-	-	-	-	LprI
SRR25158397_k127_5135060_17	1007103.AFHW01000151_gene957	1.433e-24	118.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158397_k127_5135060_0	1123371.ATXH01000005_gene2143	1.487e-296	935.0	COG0525@1|root,COG0525@2|Bacteria,2GGVS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158397_k127_5135060_8	903818.KI912268_gene2181	7.922e-77	291.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_5135060_5	1047013.AQSP01000131_gene1840	1.169e-83	303.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158397_k127_5135060_7	138119.DSY3974	3.345e-79	276.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,260QV@186807|Peptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158397_k127_5135060_6	644966.Tmar_1443	1.642e-80	278.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia	186801|Clostridia	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158397_k127_5135060_23	1120970.AUBZ01000002_gene826	2.311e-05	52.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,468PB@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158397_k127_5135060_10	1232410.KI421413_gene661	4.403e-47	176.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,43SE6@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response)	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158397_k127_5135060_4	1123073.KB899242_gene939	7.565e-85	288.0	COG1462@1|root,COG1462@2|Bacteria,1Q8KJ@1224|Proteobacteria,1RU2Q@1236|Gammaproteobacteria,1X6HV@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
SRR25158397_k127_5135060_12	1304885.AUEY01000003_gene534	1.883e-41	164.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42TBQ@68525|delta/epsilon subdivisions,2WPWC@28221|Deltaproteobacteria,2MPSG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SRR25158397_k127_5135060_21	498211.CJA_0444	3.03e-14	83.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S27A@1236|Gammaproteobacteria,1FG4Y@10|Cellvibrio	1236|Gammaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158397_k127_5135060_1	290397.Adeh_0058	2.742e-93	332.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR25158397_k127_5135060_18	373903.Hore_07620	1.921e-22	103.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,3WBY9@53433|Halanaerobiales	186801|Clostridia	NT	PFAM CheW-like domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158397_k127_5135060_20	1300143.CCAV010000007_gene3173	2.66e-14	73.0	2E5CT@1|root,3304V@2|Bacteria,4NUT2@976|Bacteroidetes,1II8Q@117743|Flavobacteriia,3ZSPQ@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5135060_9	404589.Anae109_2578	1.294e-68	245.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
SRR25158397_k127_5135060_11	483219.LILAB_31475	4.823e-46	172.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
SRR25158397_k127_5135060_14	401053.AciPR4_3802	4.88e-38	154.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria,2JIYJ@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158397_k127_5135060_19	1121440.AUMA01000009_gene536	6.573e-22	105.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2X2GQ@28221|Deltaproteobacteria,2MC2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158397_k127_5135060_16	204669.Acid345_1392	7.457e-31	129.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158397_k127_5135500_0	1192034.CAP_3147	1.803e-45	186.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2YUG5@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158397_k127_5135500_1	247490.KSU1_D0161	6.737e-21	109.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
SRR25158397_k127_5162110_1	365046.Rta_16960	9.323e-118	401.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158397_k127_5162110_8	1408422.JHYF01000002_gene2435	2.744e-24	111.0	COG3568@1|root,COG3568@2|Bacteria,1V9H0@1239|Firmicutes,24KPC@186801|Clostridia	186801|Clostridia	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158397_k127_5162110_2	1209984.BN978_04799	1.843e-67	239.0	2DBMF@1|root,2Z9YG@2|Bacteria,2I871@201174|Actinobacteria,2377T@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5162110_3	383372.Rcas_0547	7.065e-67	244.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158397_k127_5162110_6	1237149.C900_03646	1.192e-36	141.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,47QDT@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158397_k127_5162110_0	794903.OPIT5_04570	1.216e-147	496.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	irp	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_5162110_12	518766.Rmar_0611	1.174e-07	62.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158397_k127_5162110_4	379066.GAU_2456	1.166e-40	163.0	COG1376@1|root,COG1376@2|Bacteria,1ZUFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158397_k127_5162110_5	118161.KB235922_gene3690	2.93e-39	153.0	COG1487@1|root,COG1487@2|Bacteria,1G736@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_5162110_10	933262.AXAM01000020_gene49	1.033e-18	87.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158397_k127_5162110_9	1167006.UWK_00876	9.817e-20	96.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
SRR25158397_k127_5162110_11	1380347.JNII01000005_gene3610	8.818e-09	68.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	ko:K02200,ko:K04018	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19
SRR25158397_k127_5162110_7	1121468.AUBR01000034_gene1372	3.198e-31	130.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,42F43@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Galactose-1-phosphate uridyl transferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
SRR25158397_k127_5176114_2	1300345.LF41_128	5.025e-92	323.0	COG1404@1|root,COG1409@1|root,COG2304@1|root,COG3979@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG2304@2|Bacteria,COG3979@2|Bacteria,1QXFK@1224|Proteobacteria,1SJFI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_5176114_4	1247963.JPHU01000010_gene2270	4.717e-07	55.0	2E9WT@1|root,3342I@2|Bacteria,1NBEH@1224|Proteobacteria,2UFGC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	MA20_00895	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
SRR25158397_k127_5176114_0	1267533.KB906739_gene2658	5.305e-183	616.0	COG1132@1|root,COG1132@2|Bacteria,3Y2ZR@57723|Acidobacteria,2JHJA@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158397_k127_5176114_1	204669.Acid345_1514	1.636e-159	521.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158397_k127_5176114_3	706587.Desti_2078	2.416e-13	74.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WJRN@28221|Deltaproteobacteria,2MRE7@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	cytochrome c biogenesis protein, transmembrane region	dbsD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
SRR25158397_k127_5202628_1	448385.sce0431	3.498e-56	218.0	COG0457@1|root,COG0515@1|root,COG2909@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,1PEJF@1224|Proteobacteria,433Y5@68525|delta/epsilon subdivisions,2X2KM@28221|Deltaproteobacteria,2YXZ5@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SRR25158397_k127_5202628_0	709986.Deima_2193	9.743e-144	481.0	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	-	-	1.3.5.5	ko:K02293	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04786,R04787,R07510,R09652,R09653,R09654	RC01214,RC01958,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC,Amino_oxidase,NAD_binding_8
SRR25158397_k127_5202628_2	330214.NIDE0547	8.733e-49	198.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158397_k127_5202628_3	379066.GAU_2958	4.086e-08	57.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_5205041_0	1000565.METUNv1_00653	4.018e-40	160.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VM11@28216|Betaproteobacteria,2KW2P@206389|Rhodocyclales	206389|Rhodocyclales	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158397_k127_5205041_2	666686.B1NLA3E_19985	9.603e-17	82.0	COG1705@1|root,COG4193@1|root,COG1705@2|Bacteria,COG4193@2|Bacteria,1UT0U@1239|Firmicutes,4HB90@91061|Bacilli,1ZEHX@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3,SLH
SRR25158397_k127_5224734_0	1124780.ANNU01000052_gene3551	4.523e-293	942.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4,Peptidase_M1
SRR25158397_k127_5224734_3	1279009.ADICEAN_01573	1.192e-132	429.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47TWD@768503|Cytophagia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_5224734_4	880072.Desac_0624	8.639e-125	414.0	COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria,42Q9G@68525|delta/epsilon subdivisions,2WMIK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HD domain	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158397_k127_5224734_6	370438.PTH_2566	2.466e-30	130.0	COG3465@1|root,COG3465@2|Bacteria,1VC2S@1239|Firmicutes,24NAU@186801|Clostridia,265PJ@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
SRR25158397_k127_5224734_1	1300345.LF41_1043	5.111e-225	718.0	COG4206@1|root,COG4206@2|Bacteria,1QUUI@1224|Proteobacteria	1224|Proteobacteria	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug
SRR25158397_k127_5224734_5	246197.MXAN_1340	1.801e-111	379.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,42MWP@68525|delta/epsilon subdivisions,2WKGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158397_k127_5224734_2	1297742.A176_05933	4.991e-170	559.0	COG4403@1|root,COG4403@2|Bacteria,1R8VP@1224|Proteobacteria,432AY@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	Domain of unknown function (DUF4135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
SRR25158397_k127_52455_1	404589.Anae109_4096	1.559e-57	216.0	COG1538@1|root,COG1538@2|Bacteria,1PKT6@1224|Proteobacteria,4354V@68525|delta/epsilon subdivisions,2X95H@28221|Deltaproteobacteria,2Z21V@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158397_k127_52455_2	1121403.AUCV01000001_gene772	2.955e-18	91.0	COG3809@1|root,COG3809@2|Bacteria,1PZB0@1224|Proteobacteria,433GD@68525|delta/epsilon subdivisions,2WXX5@28221|Deltaproteobacteria,2MP8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
SRR25158397_k127_52455_5	1201290.M902_2199	3.012e-06	61.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Flg_new,PKD,SprB
SRR25158397_k127_52455_4	710696.Intca_1127	5.758e-07	63.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
SRR25158397_k127_52455_0	335543.Sfum_2371	1.925e-119	418.0	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
SRR25158397_k127_52455_3	357808.RoseRS_3112	3.357e-10	74.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_549393_1	1121468.AUBR01000021_gene2827	7.82e-127	427.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158397_k127_549393_2	264462.Bd2635	1.156e-75	263.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,43BHQ@68525|delta/epsilon subdivisions,2MTVP@213481|Bdellovibrionales,2X6W7@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	XdhC Rossmann domain	pcmU	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158397_k127_549393_0	448385.sce5876	1.648e-148	481.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158397_k127_549393_3	448385.sce5877	1.419e-64	227.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
SRR25158397_k127_56171_2	555079.Toce_1728	3.458e-56	211.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,42FN8@68295|Thermoanaerobacterales	186801|Clostridia	M	1,4-dihydroxy-2-naphthoate octaprenyltransferase	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158397_k127_56171_3	483219.LILAB_26100	1.701e-41	162.0	COG0398@1|root,COG0398@2|Bacteria,1N99S@1224|Proteobacteria	1224|Proteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158397_k127_56171_1	1232410.KI421426_gene1437	8.676e-61	218.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria,43UQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_56171_4	1519464.HY22_05255	7.136e-30	135.0	2ETC6@1|root,33KW3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_56171_5	1089550.ATTH01000001_gene1052	3.889e-21	108.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FJR9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158397_k127_56171_0	1549858.MC45_14125	1.282e-111	366.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2UQG8@28211|Alphaproteobacteria,2K3II@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158397_k127_564326_10	1121272.KB903291_gene3320	4.168e-68	241.0	COG0666@1|root,COG0666@2|Bacteria,2I9A2@201174|Actinobacteria,4DJ5C@85008|Micromonosporales	201174|Actinobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SRR25158397_k127_564326_4	1254432.SCE1572_39135	6.443e-97	321.0	COG1794@1|root,COG1794@2|Bacteria,1PRP1@1224|Proteobacteria,43DME@68525|delta/epsilon subdivisions,2WZYC@28221|Deltaproteobacteria,2Z2CP@29|Myxococcales	28221|Deltaproteobacteria	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158397_k127_564326_11	1121382.JQKG01000046_gene1378	8.499e-50	190.0	COG2110@1|root,COG2110@2|Bacteria,1WJ1P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158397_k127_564326_14	204669.Acid345_1301	3.315e-17	85.0	2E63P@1|root,330SQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_564326_6	1267533.KB906738_gene2414	2.122e-90	316.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE16	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158397_k127_564326_5	448385.sce1106	8.453e-97	332.0	COG3221@1|root,COG3221@2|Bacteria,1N92V@1224|Proteobacteria,42TXU@68525|delta/epsilon subdivisions,2X5QC@28221|Deltaproteobacteria,2Z36U@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
SRR25158397_k127_564326_8	44060.JODL01000004_gene2530	4.049e-73	269.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_564326_9	404589.Anae109_2307	5.198e-72	257.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158397_k127_564326_2	1184267.A11Q_77	4.546e-199	632.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2MSUT@213481|Bdellovibrionales,2WIQN@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158397_k127_564326_12	1121428.DESHY_120030___1	8.941e-47	175.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,261YZ@186807|Peptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158397_k127_564326_0	1089553.Tph_c04670	5.473e-266	843.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158397_k127_564326_1	1121439.dsat_0488	3.199e-221	697.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,43EW7@68525|delta/epsilon subdivisions,2WM9U@28221|Deltaproteobacteria,2MASI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_564326_3	671143.DAMO_2181	2.821e-179	570.0	COG1219@1|root,COG1219@2|Bacteria,2NNN2@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158397_k127_564326_7	234267.Acid_3900	1.027e-85	293.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria	57723|Acidobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158397_k127_564326_13	1410622.JNKY01000012_gene2035	6.688e-23	108.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,27I7R@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158397_k127_566181_6	1201290.M902_2809	5.154e-27	126.0	COG5424@1|root,COG5424@2|Bacteria,1Q1U2@1224|Proteobacteria,43DMI@68525|delta/epsilon subdivisions,2MT3W@213481|Bdellovibrionales,2X2Q2@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
SRR25158397_k127_566181_7	1184267.A11Q_1790	4.172e-16	88.0	2CEX1@1|root,2ZFZV@2|Bacteria,1P6SV@1224|Proteobacteria,433T6@68525|delta/epsilon subdivisions,2MTEA@213481|Bdellovibrionales,2WYHR@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_566181_5	1123248.KB893327_gene788	4.081e-104	349.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158397_k127_566181_8	710111.FraQA3DRAFT_5653	5.357e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,2I2Z1@201174|Actinobacteria,4ETFB@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158397_k127_566181_0	215803.DB30_5064	6.315e-253	831.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1Q712@1224|Proteobacteria,433SV@68525|delta/epsilon subdivisions,2WYAY@28221|Deltaproteobacteria,2YXT0@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SRR25158397_k127_566181_2	1519464.HY22_00720	1.689e-151	488.0	COG0577@1|root,COG0577@2|Bacteria,1FDBN@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_566181_1	1519464.HY22_00710	7.094e-166	533.0	COG0577@1|root,COG0577@2|Bacteria,1FDSK@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158397_k127_566181_4	452637.Oter_1637	4.197e-124	432.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia,3K76J@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158397_k127_566181_3	1267535.KB906767_gene5030	2.928e-150	490.0	COG0477@1|root,COG0477@2|Bacteria,3Y2V8@57723|Acidobacteria,2JI1F@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_568429_0	1144275.COCOR_03285	4.467e-176	588.0	COG0778@1|root,COG0778@2|Bacteria,1R0E8@1224|Proteobacteria,43CWT@68525|delta/epsilon subdivisions,2X84S@28221|Deltaproteobacteria,2Z3KW@29|Myxococcales	28221|Deltaproteobacteria	C	Lantibiotic biosynthesis dehydratase C-term	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C
SRR25158397_k127_568429_3	1242864.D187_010239	1.182e-65	241.0	COG4403@1|root,COG4403@2|Bacteria,1R8AJ@1224|Proteobacteria,43EZ6@68525|delta/epsilon subdivisions,2WYJK@28221|Deltaproteobacteria,2YZ2R@29|Myxococcales	28221|Deltaproteobacteria	V	Lanthionine synthetase C-like protein	-	-	-	ko:K20484	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	LANC_like
SRR25158397_k127_568429_4	1121920.AUAU01000012_gene2631	2.456e-61	241.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_568429_8	795666.MW7_0286	1.682e-22	101.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,1K8I2@119060|Burkholderiaceae	28216|Betaproteobacteria	G	phosphocarrier, HPr family	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRR25158397_k127_568429_6	1047013.AQSP01000135_gene1606	2.278e-31	127.0	COG2893@1|root,COG2893@2|Bacteria,2NRCX@2323|unclassified Bacteria	2|Bacteria	G	PTS system fructose IIA component	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
SRR25158397_k127_568429_5	401053.AciPR4_3950	8.685e-34	137.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158397_k127_568429_2	1267534.KB906754_gene3032	1.043e-76	266.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158397_k127_568429_1	1232410.KI421421_gene3592	1.85e-81	295.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,43TVV@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
SRR25158397_k127_568429_10	234267.Acid_1509	2.959e-05	54.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_568429_7	1499967.BAYZ01000065_gene6104	2.473e-26	115.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
SRR25158397_k127_568429_9	1033737.CAEV01000047_gene1300	7.841e-15	75.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,36ENH@31979|Clostridiaceae	186801|Clostridia	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158397_k127_578253_5	1122138.AQUZ01000003_gene613	1.26e-14	79.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158397_k127_578253_7	1304885.AUEY01000005_gene849	4.367e-12	69.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,2MM1S@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
SRR25158397_k127_578253_1	1120971.AUCA01000060_gene814	1.855e-150	488.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,2782N@186823|Alicyclobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158397_k127_578253_2	903818.KI912269_gene470	2.482e-79	289.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K02172	ko01501,ko01503,map01501,map01503	M00627,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1
SRR25158397_k127_578253_6	1121946.AUAX01000014_gene1193	2.04e-13	84.0	COG0726@1|root,COG4409@1|root,COG0726@2|Bacteria,COG4409@2|Bacteria,2GNF1@201174|Actinobacteria,4DBWD@85008|Micromonosporales	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_578253_0	649638.Trad_1124	5.344e-212	685.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1WI48@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
SRR25158397_k127_578253_3	224324.aq_132	2.829e-45	168.0	COG0054@1|root,COG0054@2|Bacteria,2G3YV@200783|Aquificae	200783|Aquificae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158397_k127_578253_4	278963.ATWD01000001_gene1848	2.918e-28	129.0	COG0781@1|root,COG0781@2|Bacteria,3Y5IW@57723|Acidobacteria,2JMVG@204432|Acidobacteriia	204432|Acidobacteriia	K	NusB family	-	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158397_k127_582588_1	1123258.AQXZ01000018_gene1010	5.644e-107	363.0	COG3848@1|root,COG3848@2|Bacteria,2IE61@201174|Actinobacteria	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
SRR25158397_k127_582588_5	1192034.CAP_2543	1.787e-67	259.0	COG0574@1|root,COG0574@2|Bacteria,1Q9MN@1224|Proteobacteria,434GW@68525|delta/epsilon subdivisions,2WYU9@28221|Deltaproteobacteria,2Z0MI@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
SRR25158397_k127_582588_4	2074.JNYD01000015_gene4602	9.228e-71	270.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158397_k127_582588_2	1121468.AUBR01000001_gene479	1.448e-98	338.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,42FJE@68295|Thermoanaerobacterales	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
SRR25158397_k127_582588_10	645991.Sgly_3341	1.966e-31	129.0	2DQF9@1|root,336H4@2|Bacteria,1VJH7@1239|Firmicutes,2541D@186801|Clostridia,265YM@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_582588_9	82654.Pse7367_0992	3.484e-43	166.0	COG4106@1|root,COG4106@2|Bacteria,1GQ61@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158397_k127_582588_11	743836.AYNA01000107_gene2162	6.422e-28	127.0	COG3675@1|root,COG3675@2|Bacteria,1NH6X@1224|Proteobacteria,2UN1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
SRR25158397_k127_582588_6	1242864.D187_001051	4.504e-52	193.0	COG0546@1|root,COG0546@2|Bacteria,1RCPM@1224|Proteobacteria,42SYW@68525|delta/epsilon subdivisions,2WP6C@28221|Deltaproteobacteria,2Z045@29|Myxococcales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158397_k127_582588_3	1089550.ATTH01000001_gene1968	8.292e-86	297.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1FJUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158397_k127_582588_0	1254432.SCE1572_18340	3.948e-172	550.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158397_k127_582588_7	485913.Krac_4124	4.179e-49	192.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158397_k127_582588_12	1454004.AW11_00236	2.336e-16	79.0	COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,2WFID@28216|Betaproteobacteria,1KQSK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158397_k127_585593_0	397945.Aave_4017	2.221e-178	565.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,2VJY0@28216|Betaproteobacteria,4ADAN@80864|Comamonadaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158397_k127_585593_2	365046.Rta_04300	6.989e-24	117.0	296MG@1|root,2ZTWR@2|Bacteria,1RJTE@1224|Proteobacteria,2VTS8@28216|Betaproteobacteria,4AEW5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_585593_1	861299.J421_4299	3.933e-96	322.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158397_k127_591300_3	204669.Acid345_1466	2.761e-86	298.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158397_k127_591300_1	1047013.AQSP01000071_gene1933	1.272e-126	428.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
SRR25158397_k127_591300_6	671143.DAMO_3132	1.906e-37	152.0	COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria	2|Bacteria	M	Cell shape-determining protein MreC	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158397_k127_591300_2	379066.GAU_1042	3.189e-99	337.0	COG1228@1|root,COG1228@2|Bacteria,1ZUVI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_591300_8	1038867.AXAY01000012_gene155	3.078e-13	74.0	2EHRH@1|root,33BH9@2|Bacteria,1NNFQ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
SRR25158397_k127_591300_0	234267.Acid_3811	8.733e-170	539.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria	57723|Acidobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158397_k127_591300_9	443144.GM21_1523	9.36e-11	74.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,LysM,fn3
SRR25158397_k127_591300_5	1123368.AUIS01000004_gene153	2.71e-59	229.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,2NCJU@225057|Acidithiobacillales	225057|Acidithiobacillales	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
SRR25158397_k127_591300_7	391625.PPSIR1_04398	2.67e-31	126.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158397_k127_591300_4	234267.Acid_7242	2.154e-64	231.0	COG3391@1|root,COG3391@2|Bacteria,3Y2SU@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158397_k127_595326_4	1205753.A989_17243	3.374e-16	85.0	COG2373@1|root,COG2373@2|Bacteria,1NAB9@1224|Proteobacteria,1T1NJ@1236|Gammaproteobacteria,1X86W@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Cytochrome oxidase complex assembly protein 1	-	-	-	-	-	-	-	-	-	-	-	-	Coa1
SRR25158397_k127_595326_1	478741.JAFS01000002_gene608	5.839e-74	259.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,37GFQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158397_k127_595326_3	1121930.AQXG01000014_gene382	7.405e-20	101.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158397_k127_595326_2	1254432.SCE1572_22910	1.789e-52	188.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158397_k127_595326_0	1047013.AQSP01000109_gene2437	4.669e-305	956.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158397_k127_601218_19	1297742.A176_00734	5.872e-23	107.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA,Response_reg
SRR25158397_k127_601218_5	644282.Deba_1916	2.42e-102	349.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_601218_23	391612.CY0110_09812	9.121e-17	94.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158397_k127_601218_17	1394178.AWOO02000059_gene583	7.287e-27	124.0	COG0457@1|root,COG0457@2|Bacteria,2IK3G@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_601218_21	670487.Ocepr_1560	1.047e-20	105.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269,HIT
SRR25158397_k127_601218_4	1267535.KB906767_gene522	6.85e-141	480.0	COG1022@1|root,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	2|Bacteria	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
SRR25158397_k127_601218_6	1267535.KB906767_gene535	7.854e-98	336.0	COG4409@1|root,COG4409@2|Bacteria,3Y8S1@57723|Acidobacteria,2JNNS@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of unknown function (DUF4185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
SRR25158397_k127_601218_3	1267535.KB906767_gene529	1.301e-144	486.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
SRR25158397_k127_601218_1	1267535.KB906767_gene521	2.204e-156	516.0	COG2192@1|root,COG2192@2|Bacteria,3Y37V@57723|Acidobacteria	57723|Acidobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158397_k127_601218_14	449447.MAE_13120	1.186e-49	185.0	28K7U@1|root,2Z9VT@2|Bacteria,1G5J6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_601218_0	682795.AciX8_0134	3.665e-201	656.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria,2JIYK@204432|Acidobacteriia	204432|Acidobacteriia	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158397_k127_601218_22	5207.AAW41580	2.562e-18	94.0	COG0500@1|root,KOG1269@2759|Eukaryota,38CU5@33154|Opisthokonta,3NTY3@4751|Fungi,3UY1Z@5204|Basidiomycota,3VDZB@5234|Tremellales	4751|Fungi	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6 SMT family	ERG6	GO:0003674,GO:0003824,GO:0003838,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0005811,GO:0005886,GO:0006066,GO:0006629,GO:0006694,GO:0006696,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008202,GO:0008204,GO:0008610,GO:0008757,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016125,GO:0016126,GO:0016128,GO:0016129,GO:0016740,GO:0016741,GO:0019867,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032259,GO:0035690,GO:0042221,GO:0042493,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044107,GO:0044108,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071944,GO:0097384,GO:0098588,GO:0098805,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653	2.1.1.41	ko:K00559	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00102	R04427,R07481	RC00003,RC01154	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_31,Sterol_MT_C
SRR25158397_k127_601218_11	112098.XP_008606153.1	2.54e-58	216.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_41,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158397_k127_601218_20	390989.JOEG01000001_gene5424	7.69e-23	110.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DAIZ@85008|Micromonosporales	201174|Actinobacteria	G	Starch synthase catalytic domain	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_601218_12	177437.HRM2_16960	1.716e-53	201.0	COG4122@1|root,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,42R09@68525|delta/epsilon subdivisions,2WMWB@28221|Deltaproteobacteria,2MJMI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158397_k127_601218_13	1288494.EBAPG3_23550	1.43e-50	189.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VU4X@28216|Betaproteobacteria,372W6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158397_k127_601218_7	1267535.KB906767_gene539	4.509e-85	304.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria,2JIGI@204432|Acidobacteriia	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_601218_25	1127134.NOCYR_4119	3.459e-11	75.0	COG0764@1|root,COG0764@2|Bacteria,2IRBF@201174|Actinobacteria,4G32M@85025|Nocardiaceae	201174|Actinobacteria	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158397_k127_601218_2	1267535.KB906767_gene539	6.422e-149	482.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria,2JIGI@204432|Acidobacteriia	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158397_k127_601218_18	768710.DesyoDRAFT_5320	8.91e-27	115.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,261X9@186807|Peptococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158397_k127_601218_15	1267535.KB906767_gene538	1.729e-37	148.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	fadD22	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0016874,GO:0042546,GO:0044085,GO:0044238,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:1901576	2.3.1.165,4.1.3.39,6.2.1.20,6.2.1.3,6.2.1.50	ko:K01666,ko:K01897,ko:K01909,ko:K02078,ko:K04791,ko:K12424,ko:K12436,ko:K12439,ko:K12442,ko:K12443,ko:K15320,ko:K15673,ko:K16030,ko:K16128	ko00061,ko00071,ko00360,ko00362,ko00621,ko00622,ko01051,ko01052,ko01053,ko01054,ko01059,ko01100,ko01120,ko01130,ko01212,ko01220,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00360,map00362,map00621,map00622,map01051,map01052,map01053,map01054,map01059,map01100,map01120,map01130,map01212,map01220,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00545,M00569,M00829	R00750,R01280,R01406,R07253,R11608,R11872,R11873	RC00004,RC00014,RC00039,RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000,ko01004,ko01008,ko04147	4.C.1.1	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158397_k127_601218_9	997346.HMPREF9374_0896	2.167e-63	237.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,27BBK@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	KR domain	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
SRR25158397_k127_601218_8	1267535.KB906767_gene523	2.52e-74	258.0	COG0623@1|root,COG0623@2|Bacteria	2|Bacteria	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	fabL	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158397_k127_601218_16	1121272.KB903253_gene6911	2.512e-35	135.0	COG3291@1|root,COG3291@2|Bacteria,2GKA0@201174|Actinobacteria,4D9FV@85008|Micromonosporales	201174|Actinobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
SRR25158397_k127_604039_33	977880.pRALTA_0425	6.911e-05	56.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,1R66H@1224|Proteobacteria,2VPKN@28216|Betaproteobacteria,1KD5K@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Evidence 1c Function experimentally demonstrated in the studied genus	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	Esterase_phd
SRR25158397_k127_604039_7	118163.Ple7327_1968	2.15e-75	278.0	COG2931@1|root,COG2931@2|Bacteria,1GHAU@1117|Cyanobacteria,3VMMX@52604|Pleurocapsales	1117|Cyanobacteria	Q	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158397_k127_604039_32	1463857.JOFZ01000007_gene307	6.974e-08	66.0	COG3509@1|root,COG3979@1|root,COG3509@2|Bacteria,COG3979@2|Bacteria,2GMTA@201174|Actinobacteria	201174|Actinobacteria	Q	Esterase, phb depolymerase family	phaZ1	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
SRR25158397_k127_604039_10	118163.Ple7327_1968	4.075e-72	268.0	COG2931@1|root,COG2931@2|Bacteria,1GHAU@1117|Cyanobacteria,3VMMX@52604|Pleurocapsales	1117|Cyanobacteria	Q	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158397_k127_604039_12	357808.RoseRS_2377	8.783e-66	243.0	COG2244@1|root,COG2244@2|Bacteria,2G7NK@200795|Chloroflexi,3761V@32061|Chloroflexia	32061|Chloroflexia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158397_k127_604039_36	208444.JNYY01000032_gene3692	0.0002146	53.0	COG3173@1|root,COG3173@2|Bacteria,2GNNV@201174|Actinobacteria,4E20X@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH
SRR25158397_k127_604039_17	316274.Haur_3579	8.408e-29	135.0	COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158397_k127_604039_35	1136177.KCA1_1787	0.0001744	55.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae	91061|Bacilli	M	biosynthesis protein	epsB	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
SRR25158397_k127_604039_5	1194972.MVAC_23220	1.661e-79	282.0	28K7U@1|root,2Z9VT@2|Bacteria,2IQDT@201174|Actinobacteria,23AY2@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158397_k127_604039_0	211165.AJLN01000149_gene6647	3.304e-274	888.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD
SRR25158397_k127_604039_15	1123371.ATXH01000005_gene2046	1.186e-48	202.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158397_k127_604039_31	1449058.JQKT01000010_gene2055	1.684e-08	69.0	COG0726@1|root,COG0726@2|Bacteria,2I3D0@201174|Actinobacteria	201174|Actinobacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158397_k127_604039_25	1122609.AUGT01000008_gene2868	2.581e-15	91.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
SRR25158397_k127_604039_13	1123401.JHYQ01000021_gene1059	2.402e-60	239.0	COG1520@1|root,COG1520@2|Bacteria,1R4I1@1224|Proteobacteria,1SJ0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_604039_29	379066.GAU_3657	2.311e-09	61.0	2AU93@1|root,31JWF@2|Bacteria,1ZV74@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_604039_20	266940.Krad_2102	1.085e-26	117.0	COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria	201174|Actinobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
SRR25158397_k127_604039_4	497964.CfE428DRAFT_1182	2.515e-108	387.0	COG0300@1|root,COG0300@2|Bacteria,46TCZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158397_k127_604039_1	1185652.USDA257_c04170	2.202e-248	788.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,4B9N1@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158397_k127_604039_19	357808.RoseRS_4380	3.823e-27	118.0	2EMP9@1|root,33FBQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_604039_14	1207076.ALAT01000143_gene484	1.127e-50	183.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1Z33C@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
SRR25158397_k127_604039_22	1121017.AUFG01000067_gene153	1.398e-19	94.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,4FGZI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158397_k127_604039_9	269799.Gmet_0890	5.108e-74	262.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158397_k127_604039_37	696747.NIES39_O05370	0.0007059	49.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,TPR_1,TPR_11,TPR_2,TPR_4,TPR_8,Trypsin_2
SRR25158397_k127_604039_2	1047013.AQSP01000115_gene336	7.052e-135	467.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
SRR25158397_k127_604039_8	404589.Anae109_1709	3.118e-74	263.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,4304Z@68525|delta/epsilon subdivisions,2WVJ8@28221|Deltaproteobacteria,2YV3F@29|Myxococcales	28221|Deltaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	topI	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158397_k127_604039_28	1242864.D187_007279	1.563e-09	71.0	COG1807@1|root,COG1807@2|Bacteria,1REWS@1224|Proteobacteria,435AS@68525|delta/epsilon subdivisions,2WZMW@28221|Deltaproteobacteria,2Z2E9@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_604039_27	443144.GM21_3210	1.773e-10	73.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_604039_30	526226.Gbro_3036	6.717e-09	70.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4GC8K@85026|Gordoniaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158397_k127_604039_11	204669.Acid345_0557	8.202e-70	249.0	COG1559@1|root,COG1559@2|Bacteria,3Y2RD@57723|Acidobacteria,2JIQ0@204432|Acidobacteriia	204432|Acidobacteriia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158397_k127_604039_26	760568.Desku_2022	4.626e-13	77.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,2622P@186807|Peptococcaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158397_k127_604039_3	204669.Acid345_0689	3.756e-134	438.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158397_k127_604039_34	177437.HRM2_05010	0.0001053	55.0	COG0784@1|root,COG0784@2|Bacteria,1RHWK@1224|Proteobacteria,42SCZ@68525|delta/epsilon subdivisions,2WPGH@28221|Deltaproteobacteria,2MK6H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SRR25158397_k127_604039_24	1499967.BAYZ01000075_gene2072	3.93e-17	87.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158397_k127_604039_16	314285.KT71_04350	1.001e-40	168.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158397_k127_604039_23	309801.trd_1801	4.448e-19	103.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_604039_18	1128421.JAGA01000003_gene3091	1.357e-28	134.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158397_k127_604039_6	864702.OsccyDRAFT_1593	3.868e-78	269.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158397_k127_604039_21	635013.TherJR_1892	1.088e-24	118.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_613374_0	247490.KSU1_D0967	3.727e-43	164.0	COG0735@1|root,COG0735@2|Bacteria,2IZJY@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158397_k127_613374_1	1165096.ARWF01000001_gene2279	5.461e-39	155.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	DUF2318,FTR1
SRR25158397_k127_613374_3	592028.GCWU000321_00910	1.335e-14	84.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4H4ZW@909932|Negativicutes	909932|Negativicutes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158397_k127_613374_2	1121920.AUAU01000019_gene2603	2.839e-25	111.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12065	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Porin_O_P
SRR25158397_k127_61620_11	643867.Ftrac_1661	1.773e-11	75.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158397_k127_61620_13	316057.RPD_2550	1.784e-06	56.0	2DMHT@1|root,32RN3@2|Bacteria,1N0KK@1224|Proteobacteria,2UCFK@28211|Alphaproteobacteria,3JZ5E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_36130	-	-	-	-	-	-	-	-	-	-	-	PEGA
SRR25158397_k127_61620_3	1267534.KB906754_gene2794	1.36e-84	286.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158397_k127_61620_7	1122611.KB903960_gene4317	9.547e-30	130.0	2BRP5@1|root,32KNS@2|Bacteria,2GRXV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_61620_0	1183438.GKIL_0950	1.876e-199	627.0	COG1063@1|root,COG1063@2|Bacteria,1G2NW@1117|Cyanobacteria	1117|Cyanobacteria	E	Alcohol dehydrogenase GroES-associated	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158397_k127_61620_5	713586.KB900536_gene459	2.327e-45	170.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,1S2G0@1236|Gammaproteobacteria,1WZNN@135613|Chromatiales	135613|Chromatiales	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR25158397_k127_61620_6	715451.ambt_03035	1.486e-38	152.0	COG3772@1|root,COG3772@2|Bacteria,1R3WD@1224|Proteobacteria,1SNI1@1236|Gammaproteobacteria,46AKD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_61620_8	1380391.JIAS01000020_gene1481	2.041e-29	125.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1Q297@1224|Proteobacteria,2U15B@28211|Alphaproteobacteria,2JYHI@204441|Rhodospirillales	28211|Alphaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158397_k127_61620_2	1907.SGLAU_30835	1.188e-86	298.0	COG0300@1|root,COG0300@2|Bacteria,2GJ1R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158397_k127_61620_1	1056820.KB900671_gene2460	1.238e-181	644.0	COG1361@1|root,COG2885@1|root,COG3266@1|root,COG3637@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG3266@2|Bacteria,COG3637@2|Bacteria,1QVSF@1224|Proteobacteria,1T46K@1236|Gammaproteobacteria,2PQ95@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,OmpA_membrane
SRR25158397_k127_61620_12	351746.Pput_4107	2.548e-09	73.0	2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage tail tube, TTP, lambda-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TTP_11
SRR25158397_k127_61620_14	1123261.AXDW01000007_gene2285	0.0007626	55.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	fn3
SRR25158397_k127_61620_9	927677.ALVU02000001_gene1177	1.637e-25	127.0	COG1361@1|root,COG2304@1|root,COG4870@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG4870@2|Bacteria,1G2M0@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158397_k127_61620_4	395493.BegalDRAFT_1833	4.576e-47	198.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
SRR25158397_k127_61620_10	234267.Acid_6815	1.165e-18	86.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158397_k127_617473_8	314260.PB2503_13399	1.281e-07	62.0	COG3047@1|root,COG3047@2|Bacteria,1N082@1224|Proteobacteria,2UDHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158397_k127_617473_0	204669.Acid345_1052	2.9e-142	481.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158397_k127_617473_6	234267.Acid_2602	2.046e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,3Y893@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_617473_1	391603.FBALC1_08338	1.397e-37	156.0	COG5640@1|root,COG5640@2|Bacteria,4P71W@976|Bacteroidetes,1IBSM@117743|Flavobacteriia	976|Bacteroidetes	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158397_k127_617473_2	1237149.C900_02473	1.856e-37	152.0	COG0457@1|root,COG0457@2|Bacteria,4NUBH@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_617473_5	1163409.UUA_01015	3.404e-20	106.0	COG2207@1|root,COG2207@2|Bacteria,1QVRF@1224|Proteobacteria,1SMB9@1236|Gammaproteobacteria,1X4Y8@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158397_k127_617473_4	700598.Niako_0587	8.703e-37	150.0	COG2227@1|root,COG2227@2|Bacteria,4NZ87@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31,Methyltransf_9
SRR25158397_k127_617473_3	1297742.A176_03806	6.837e-37	143.0	2BU8D@1|root,32PHV@2|Bacteria,1NANB@1224|Proteobacteria,433N8@68525|delta/epsilon subdivisions,2WXKZ@28221|Deltaproteobacteria,2Z2G5@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
SRR25158397_k127_617473_7	660470.Theba_2513	4.047e-14	73.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
SRR25158397_k127_633695_3	1382359.JIAL01000001_gene1544	3.418e-67	233.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158397_k127_633695_5	278963.ATWD01000001_gene3043	3.831e-15	89.0	COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria,2JJMD@204432|Acidobacteriia	204432|Acidobacteriia	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_633695_4	868595.Desca_2475	3.57e-66	229.0	COG0288@1|root,COG0288@2|Bacteria,1VSV8@1239|Firmicutes,24GE5@186801|Clostridia,2652J@186807|Peptococcaceae	186801|Clostridia	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158397_k127_633695_0	479434.Sthe_0131	1.183e-222	709.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi,27XU1@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158397_k127_633695_1	316067.Geob_1382	2.899e-127	430.0	2EWA0@1|root,33PNR@2|Bacteria,1NSPR@1224|Proteobacteria,42YN1@68525|delta/epsilon subdivisions,2WTJI@28221|Deltaproteobacteria,43U3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_633695_2	1121428.DESHY_80117___1	1.281e-75	270.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,260TU@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158397_k127_633889_0	926549.KI421517_gene3934	2.295e-304	953.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158397_k127_633889_3	471852.Tcur_3534	4.651e-70	245.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4EFG2@85012|Streptosporangiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158397_k127_633889_4	204669.Acid345_2290	1.912e-63	225.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03470	Fer2_4,Fer4,Fer4_21,Fer4_7
SRR25158397_k127_633889_1	479432.Sros_3728	7.82e-302	947.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GJCK@201174|Actinobacteria,4EFRS@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123,ko:K00372	ko00630,ko00680,ko00910,ko01100,ko01120,ko01200,map00630,map00680,map00910,map01100,map01120,map01200	M00531	R00519,R00798,R01106	RC02796,RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158397_k127_633889_2	204669.Acid345_2292	2.63e-112	368.0	COG0437@1|root,COG0437@2|Bacteria,3Y47T@57723|Acidobacteria,2JMIW@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11
SRR25158397_k127_633889_5	290397.Adeh_0822	7.855e-41	162.0	COG3301@1|root,COG3301@2|Bacteria,1RDKK@1224|Proteobacteria,42ZVT@68525|delta/epsilon subdivisions,2WVHY@28221|Deltaproteobacteria,2YWTF@29|Myxococcales	28221|Deltaproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158397_k127_633889_6	349124.Hhal_0678	4.314e-05	50.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales	135613|Chromatiales	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158397_k127_640293_0	1144275.COCOR_04468	0.0	1677.0	COG0714@1|root,COG1196@1|root,COG0714@2|Bacteria,COG1196@2|Bacteria,1NSN5@1224|Proteobacteria,437FG@68525|delta/epsilon subdivisions,2X2N3@28221|Deltaproteobacteria,2YTXE@29|Myxococcales	28221|Deltaproteobacteria	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF3686
SRR25158397_k127_640293_8	1144275.COCOR_06753	9.464e-20	99.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1RAJF@1224|Proteobacteria,435FC@68525|delta/epsilon subdivisions,2WZSW@28221|Deltaproteobacteria,2Z2PC@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158397_k127_640293_7	251221.35211908	2.059e-34	143.0	COG1621@1|root,COG3191@1|root,COG1621@2|Bacteria,COG3191@2|Bacteria,1GR11@1117|Cyanobacteria	2|Bacteria	EQ	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
SRR25158397_k127_640293_6	1384054.N790_02955	9.494e-36	158.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158397_k127_640293_4	1144275.COCOR_01810	2.86e-48	197.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	yehT	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_640293_3	1173027.Mic7113_3330	2.955e-77	266.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,1HAPK@1150|Oscillatoriales	1117|Cyanobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRR25158397_k127_640293_5	502025.Hoch_0805	5.527e-41	164.0	COG4076@1|root,COG4076@2|Bacteria,1Q5QG@1224|Proteobacteria,43A7U@68525|delta/epsilon subdivisions,2X218@28221|Deltaproteobacteria,2Z25F@29|Myxococcales	28221|Deltaproteobacteria	S	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PrmA
SRR25158397_k127_640293_1	1282362.AEAC466_21360	5.32e-185	606.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2KFG4@204458|Caulobacterales	204458|Caulobacterales	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158397_k127_640293_2	246197.MXAN_3119	2.549e-77	267.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
SRR25158397_k127_648737_11	886293.Sinac_1585	1.856e-37	163.0	COG3119@1|root,COG3119@2|Bacteria,2J1Z5@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158397_k127_648737_2	398767.Glov_0469	1.754e-161	524.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	ribonuclease Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158397_k127_648737_4	1437425.CSEC_0969	4.417e-103	344.0	COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae	204428|Chlamydiae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158397_k127_648737_9	1254432.SCE1572_21210	2.707e-56	205.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158397_k127_648737_6	234267.Acid_5756	2.39e-86	293.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158397_k127_648737_13	661478.OP10G_4489	6.035e-20	100.0	2A52F@1|root,30TQU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_648737_8	105559.Nwat_1040	2.87e-57	207.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1X1P9@135613|Chromatiales	135613|Chromatiales	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158397_k127_648737_1	1254432.SCE1572_35510	1.502e-170	587.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158397_k127_648737_0	1340493.JNIF01000003_gene1675	1.34e-232	753.0	COG1629@1|root,COG4771@2|Bacteria,3Y2HF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158397_k127_648737_16	1415780.JPOG01000001_gene663	1.253e-06	59.0	COG1309@1|root,COG1309@2|Bacteria,1MV2V@1224|Proteobacteria,1SZ3F@1236|Gammaproteobacteria,1X6R6@135614|Xanthomonadales	135614|Xanthomonadales	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
SRR25158397_k127_648737_10	1267534.KB906755_gene4491	3.042e-42	167.0	COG1566@1|root,COG1566@2|Bacteria,3Y53G@57723|Acidobacteria	57723|Acidobacteria	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158397_k127_648737_5	661478.OP10G_2908	4.53e-100	347.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158397_k127_648737_7	1150621.SMUL_1322	1.28e-81	297.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42N83@68525|delta/epsilon subdivisions,2YTKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158397_k127_648737_15	944480.ATUV01000002_gene164	3.174e-13	72.0	COG1598@1|root,COG1598@2|Bacteria,1Q9I0@1224|Proteobacteria,434E9@68525|delta/epsilon subdivisions,2WYRJ@28221|Deltaproteobacteria,2M7NT@213113|Desulfurellales	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158397_k127_648737_14	243090.RB3259	3.167e-19	89.0	COG1724@1|root,COG1724@2|Bacteria,2J477@203682|Planctomycetes	203682|Planctomycetes	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158397_k127_648737_3	1499967.BAYZ01000097_gene4376	3.141e-111	365.0	COG1220@1|root,COG1220@2|Bacteria,2NP00@2323|unclassified Bacteria	2|Bacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158397_k127_666408_4	1408444.JHYC01000009_gene1668	6.303e-29	132.0	COG1807@1|root,COG1807@2|Bacteria,1QC7N@1224|Proteobacteria,1T7WU@1236|Gammaproteobacteria,1JFYQ@118969|Legionellales	118969|Legionellales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_666408_0	1032480.MLP_38390	2.432e-55	205.0	COG5549@1|root,COG5549@2|Bacteria,2I9HV@201174|Actinobacteria	201174|Actinobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
SRR25158397_k127_666408_2	172088.AUGA01000075_gene7045	7.876e-33	141.0	COG4249@1|root,COG4249@2|Bacteria,1NIWD@1224|Proteobacteria,2UJXM@28211|Alphaproteobacteria,3K5MP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158397_k127_666408_3	331678.Cphamn1_1328	5.12e-30	136.0	2CFUR@1|root,33M72@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_666408_1	497965.Cyan7822_3499	5.835e-34	149.0	28YQ6@1|root,2ZKHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_692834_5	1122176.KB903531_gene2817	1.388e-80	282.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1IWBX@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
SRR25158397_k127_692834_7	1449076.JOOE01000004_gene117	2.906e-32	134.0	COG0604@1|root,COG0604@2|Bacteria,1QY0U@1224|Proteobacteria	1224|Proteobacteria	C	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158397_k127_692834_2	401053.AciPR4_2317	1.28e-133	460.0	COG2132@1|root,COG2132@2|Bacteria,3Y65V@57723|Acidobacteria,2JMCT@204432|Acidobacteriia	204432|Acidobacteriia	Q	PFAM multicopper oxidase type 2	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158397_k127_692834_9	935261.JAGL01000007_gene2549	1.933e-15	85.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria,43QCN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,DUF4437
SRR25158397_k127_692834_8	1352941.M877_04220	8.583e-23	106.0	28Q4M@1|root,2ZCMV@2|Bacteria,2IH45@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_692834_0	1429916.X566_05380	2.386e-256	818.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TT2P@28211|Alphaproteobacteria,3JWSW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158397_k127_692834_11	376686.Fjoh_4325	1.993e-09	71.0	COG3637@1|root,COG3637@2|Bacteria,4NVQZ@976|Bacteroidetes,1IAJU@117743|Flavobacteriia,2NV9E@237|Flavobacterium	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_692834_6	1254432.SCE1572_30035	2.114e-66	232.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,430PA@68525|delta/epsilon subdivisions,2WZ68@28221|Deltaproteobacteria,2Z1EX@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158397_k127_692834_4	1121943.KB899989_gene3421	2.421e-112	368.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158397_k127_692834_1	330214.NIDE2498	3.851e-170	571.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	CW_binding_1,Lactamase_B
SRR25158397_k127_692834_3	1242864.D187_002505	1.977e-122	402.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,42P8U@68525|delta/epsilon subdivisions,2WTQE@28221|Deltaproteobacteria,2YZNT@29|Myxococcales	28221|Deltaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158397_k127_692834_10	1047013.AQSP01000103_gene1162	3.487e-13	82.0	2E93F@1|root,333CD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_718336_16	1123065.ATWL01000002_gene1653	7.372e-14	71.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158397_k127_718336_18	266265.Bxe_A4145	0.0002798	54.0	COG3637@1|root,COG3637@2|Bacteria,1N7IC@1224|Proteobacteria,2VVZ0@28216|Betaproteobacteria,1K72N@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	pagL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PagL
SRR25158397_k127_718336_0	398767.Glov_1605	6.328e-151	490.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,43STX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158397_k127_718336_11	592029.DDD_0403	1.238e-42	164.0	COG4276@1|root,COG4276@2|Bacteria,4NQ3V@976|Bacteroidetes,1I398@117743|Flavobacteriia,3HKE0@363408|Nonlabens	976|Bacteroidetes	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_718336_13	1307759.JOMJ01000003_gene1216	6.083e-24	118.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158397_k127_718336_10	1157490.EL26_16960	3.366e-50	200.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,2785U@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
SRR25158397_k127_718336_3	1089546.AQUI01000002_gene2068	1.196e-110	384.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,409RH@622450|Actinopolysporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158397_k127_718336_5	1173021.ALWA01000037_gene3449	4.234e-77	267.0	COG1234@1|root,COG1234@2|Bacteria,1G16X@1117|Cyanobacteria	1117|Cyanobacteria	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158397_k127_718336_2	909663.KI867150_gene1369	6.765e-121	406.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,42SZH@68525|delta/epsilon subdivisions,2WPX7@28221|Deltaproteobacteria,2MQHU@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158397_k127_718336_7	768671.ThimaDRAFT_1329	1.034e-65	231.0	COG4636@1|root,COG4636@2|Bacteria,1NTAK@1224|Proteobacteria,1SM5Q@1236|Gammaproteobacteria,1X0G8@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_718336_4	675812.VHA_002378	2.898e-77	278.0	COG1361@1|root,COG1361@2|Bacteria,1NNGX@1224|Proteobacteria,1T51T@1236|Gammaproteobacteria,1Y0MV@135623|Vibrionales	135623|Vibrionales	M	Toxin with a conserved tryptophan and TIP tripeptide motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Tox-WTIP
SRR25158397_k127_718336_9	338966.Ppro_1811	2.904e-57	228.0	COG4447@1|root,COG4447@2|Bacteria,1NRDC@1224|Proteobacteria,42R9N@68525|delta/epsilon subdivisions,2WN6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158397_k127_718336_6	880072.Desac_1818	4.668e-77	287.0	COG3292@1|root,COG3292@2|Bacteria,1QMJ4@1224|Proteobacteria,42RQF@68525|delta/epsilon subdivisions,2WNII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
SRR25158397_k127_718336_8	485913.Krac_5981	3.517e-59	236.0	COG3299@1|root,COG3299@2|Bacteria,2G5JN@200795|Chloroflexi	200795|Chloroflexi	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158397_k127_718336_1	880072.Desac_1816	1.925e-123	430.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,42MUS@68525|delta/epsilon subdivisions,2WKK4@28221|Deltaproteobacteria,2MRM4@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_718336_14	880072.Desac_1815	2.838e-18	93.0	COG3628@1|root,COG3628@2|Bacteria,1N039@1224|Proteobacteria,42V16@68525|delta/epsilon subdivisions,2WREE@28221|Deltaproteobacteria,2MQQQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SRR25158397_k127_718336_12	880072.Desac_1814	8.711e-25	113.0	2CE1N@1|root,32RYY@2|Bacteria,1NB5H@1224|Proteobacteria,431G8@68525|delta/epsilon subdivisions,2WWTX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_718336_15	146922.JOFU01000059_gene898	2.395e-14	85.0	COG3266@1|root,COG3266@2|Bacteria,2IHVR@201174|Actinobacteria	201174|Actinobacteria	N	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158397_k127_737955_5	1121920.AUAU01000009_gene1941	7.12e-32	142.0	COG2206@1|root,COG2206@2|Bacteria,3Y52R@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_737955_0	485913.Krac_1006	1.435e-97	331.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158397_k127_737955_3	1089553.Tph_c15800	5.419e-46	186.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,42FXA@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158397_k127_737955_1	1282876.BAOK01000001_gene1148	3.625e-57	212.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,4BQ55@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	FecCD transport family	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158397_k127_737955_2	485913.Krac_4529	3.094e-54	194.0	COG2329@1|root,COG2329@2|Bacteria,2G8Z3@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
SRR25158397_k127_737955_4	35841.BT1A1_2800	1.199e-32	138.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus	91061|Bacilli	P	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158397_k127_737955_6	1267533.KB906734_gene4322	3.816e-05	53.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158397_k127_76599_5	370438.PTH_1587	6.709e-07	55.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,260ZW@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SRR25158397_k127_76599_0	1128421.JAGA01000003_gene2944	3.963e-174	564.0	COG1640@1|root,COG1640@2|Bacteria,2NP2W@2323|unclassified Bacteria	2|Bacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	iJN678.malQ	Glyco_hydro_77
SRR25158397_k127_76599_1	84531.JMTZ01000021_gene3824	3.118e-43	180.0	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria,1X77S@135614|Xanthomonadales	135614|Xanthomonadales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158397_k127_76599_3	247490.KSU1_D0348	8.162e-18	90.0	COG4636@1|root,COG4636@2|Bacteria,2J1JY@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_76599_2	1121472.AQWN01000004_gene659	5.077e-34	141.0	COG4636@1|root,COG4636@2|Bacteria,1VEA1@1239|Firmicutes,250SS@186801|Clostridia,265AQ@186807|Peptococcaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158397_k127_76599_4	1479237.JMLY01000001_gene2634	9.83e-10	62.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,1T1IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158397_k127_77450_5	1313301.AUGC01000007_gene554	2.323e-72	252.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158397_k127_77450_4	671143.DAMO_0676	3.09e-85	302.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158397_k127_77450_2	243231.GSU2278	3.141e-115	403.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,43U2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158397_k127_77450_8	1340493.JNIF01000003_gene2966	1.395e-51	201.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158397_k127_77450_12	314270.RB2083_3938	2.301e-32	137.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,3ZHDN@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	MA20_44635	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158397_k127_77450_17	378806.STAUR_1396	3.255e-20	103.0	COG1651@1|root,COG1651@2|Bacteria,1NZPQ@1224|Proteobacteria,42U1T@68525|delta/epsilon subdivisions,2WQH9@28221|Deltaproteobacteria,2YXM2@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158397_k127_77450_13	378806.STAUR_0399	5.655e-31	127.0	COG0517@1|root,COG0517@2|Bacteria,1N9X9@1224|Proteobacteria,4375S@68525|delta/epsilon subdivisions,2X9SS@28221|Deltaproteobacteria,2YXN7@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158397_k127_77450_16	522306.CAP2UW1_0272	2.836e-22	106.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,1KQYC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158397_k127_77450_1	204669.Acid345_1338	6.704e-133	429.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria,2JHRI@204432|Acidobacteriia	204432|Acidobacteriia	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158397_k127_77450_14	234267.Acid_1797	1.591e-23	114.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
SRR25158397_k127_77450_18	1476876.JOJO01000021_gene752	5.523e-15	87.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the peptidase S33 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158397_k127_77450_10	929556.Solca_0685	8.043e-43	160.0	COG0681@1|root,COG0681@2|Bacteria,4NSIR@976|Bacteroidetes,1ITMV@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_77450_7	1297742.A176_03422	2.323e-54	202.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158397_k127_77450_11	565045.NOR51B_2732	2.004e-41	160.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECO26_1355.ECO26_4302	Hydrolase_3
SRR25158397_k127_77450_0	398767.Glov_2760	4.257e-156	507.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158397_k127_77450_20	309799.DICTH_0778	1.034e-05	56.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Cdd1,IMS,IMS_C,IMS_HHH
SRR25158397_k127_77450_9	686340.Metal_0994	4.924e-49	181.0	COG1573@1|root,COG1573@2|Bacteria,1QJIF@1224|Proteobacteria,1THIQ@1236|Gammaproteobacteria,1XEAT@135618|Methylococcales	135618|Methylococcales	L	uracil-DNA	-	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158397_k127_77450_6	648885.KB316282_gene1494	1.508e-62	228.0	COG0730@1|root,COG0730@2|Bacteria,1PGTZ@1224|Proteobacteria,2U5IZ@28211|Alphaproteobacteria,1JTSQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158397_k127_77450_15	153721.MYP_122	1.491e-22	103.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRR25158397_k127_77450_3	1279017.AQYJ01000023_gene3094	1.581e-101	338.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,465D3@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158397_k127_776419_3	1449353.JQMQ01000005_gene5189	0.0005554	52.0	COG5434@1|root,COG5434@2|Bacteria,2GKCR@201174|Actinobacteria,2NGMR@228398|Streptacidiphilus	201174|Actinobacteria	GM	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,F5_F8_type_C,NosD,Pectate_lyase_3
SRR25158397_k127_776419_0	1278073.MYSTI_02641	0.0	1067.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158397_k127_776419_1	523791.Kkor_1131	3.591e-50	191.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yijE_3	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158397_k127_776419_2	448385.sce0450	1.991e-46	171.0	COG0654@1|root,COG0654@2|Bacteria,1N7Z4@1224|Proteobacteria,43BXN@68525|delta/epsilon subdivisions,2X78F@28221|Deltaproteobacteria,2YU0J@29|Myxococcales	28221|Deltaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_7786_2	1125863.JAFN01000001_gene2253	4.81e-76	290.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_7786_0	880073.Calab_3284	3.101e-119	418.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158397_k127_7786_10	313606.M23134_08374	4.837e-12	80.0	COG1520@1|root,COG3405@1|root,COG4733@1|root,COG4886@1|root,COG1520@2|Bacteria,COG3405@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14,fn3
SRR25158397_k127_7786_7	382464.ABSI01000012_gene2139	3.448e-27	130.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,VPEP
SRR25158397_k127_7786_13	1279009.ADICEAN_00251	1.788e-10	74.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SRR25158397_k127_7786_5	382464.ABSI01000012_gene2139	3.001e-32	145.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,VPEP
SRR25158397_k127_7786_1	1387312.BAUS01000011_gene1928	1.933e-76	271.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KKRI@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158397_k127_7786_3	1379270.AUXF01000004_gene3226	1.837e-42	173.0	COG2094@1|root,COG2094@2|Bacteria,1ZTNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158397_k127_7786_12	1349785.BAUG01000026_gene1593	1.65e-10	74.0	COG1404@1|root,COG3291@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,4NJK3@976|Bacteroidetes,1I16K@117743|Flavobacteriia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
SRR25158397_k127_7786_4	745776.DGo_CA2513	5.743e-35	141.0	COG1739@1|root,COG1739@2|Bacteria,1WJVU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
SRR25158397_k127_7786_15	1403819.BATR01000094_gene2942	2.583e-07	58.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158397_k127_7786_9	861299.J421_4379	8.71e-14	84.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158397_k127_7786_6	1297865.APJD01000011_gene6806	5.571e-28	129.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,2TUYH@28211|Alphaproteobacteria,3JSAB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_7786_16	1198114.AciX9_3489	0.0002922	49.0	2EA3B@1|root,3348D@2|Bacteria,3Y5J1@57723|Acidobacteria,2JJZE@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_7786_11	1121430.JMLG01000003_gene651	1.995e-11	74.0	2DQUD@1|root,338R2@2|Bacteria,1VXI6@1239|Firmicutes,251UZ@186801|Clostridia,265H2@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_7786_8	204669.Acid345_0034	9.953e-20	100.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158397_k127_7786_14	204669.Acid345_2692	1.944e-10	74.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_781281_4	1144275.COCOR_05170	2.798e-53	196.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_781281_0	1282360.ABAC460_22805	7.336e-117	399.0	COG0520@1|root,COG0520@2|Bacteria,1NRXE@1224|Proteobacteria	1224|Proteobacteria	E	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Methyltransf_25
SRR25158397_k127_781281_6	1282360.ABAC460_22800	1.084e-30	133.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.7.7.80,2.8.1.1,2.8.1.11	ko:K02439,ko:K21147	ko00920,ko01110,ko01120,ko04122,map00920,map01110,map01120,map04122	-	R01931,R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_781281_3	1282360.ABAC460_22795	2.142e-57	213.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2U4F1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158397_k127_781281_1	1282360.ABAC460_22785	1.619e-81	284.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U25R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158397_k127_781281_2	1254432.SCE1572_26550	2.802e-63	232.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158397_k127_781281_5	1267533.KB906738_gene2268	7.731e-50	201.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158397_k127_781281_7	1123319.AUBE01000001_gene1760	1.104e-16	95.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria	201174|Actinobacteria	CH	PFAM monooxygenase FAD-binding	-	-	1.14.13.232	ko:K14253	ko00253,ko01057,ko01130,map00253,map01057,map01130	M00780,M00823	R05463	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158397_k127_784608_1	1340493.JNIF01000003_gene2186	1.309e-214	700.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
SRR25158397_k127_784608_3	903818.KI912268_gene2038	1.513e-37	151.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	mauE	-	-	-	-	-	-	-	-	-	-	-	MauE
SRR25158397_k127_784608_5	903818.KI912268_gene2039	8.121e-25	122.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	MA20_21580	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Rhodanese
SRR25158397_k127_784608_0	713587.THITH_11260	0.0	1108.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158397_k127_784608_6	2002.JOEQ01000012_gene5751	4.317e-23	111.0	COG1215@1|root,COG1215@2|Bacteria,2IAQ1@201174|Actinobacteria,4EMAC@85012|Streptosporangiales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
SRR25158397_k127_784608_2	1229780.BN381_130153	8.889e-95	338.0	COG0500@1|root,COG2226@2|Bacteria,2IEI0@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_11
SRR25158397_k127_784608_4	926562.Oweho_1726	1.288e-36	160.0	COG2265@1|root,COG2265@2|Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_19,Methyltransf_25
SRR25158397_k127_784608_7	234267.Acid_0107	2.606e-21	98.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158397_k127_790538_2	1242864.D187_000271	1.95e-90	305.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2YX13@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
SRR25158397_k127_790538_1	717785.HYPMC_4485	9.232e-99	334.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,3N6GI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158397_k127_790538_4	118168.MC7420_4742	2.137e-49	201.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
SRR25158397_k127_790538_3	1121413.JMKT01000015_gene314	5.52e-73	275.0	COG2202@1|root,COG3920@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MAT9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,SBP_bac_3,sCache_2
SRR25158397_k127_790538_0	290397.Adeh_1758	5.911e-125	418.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJU@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_790538_5	1499967.BAYZ01000105_gene3475	1.041e-43	168.0	28UH1@1|root,2ZGMU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR25158397_k127_795398_1	1434929.X946_2012	2.702e-87	302.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2VH7E@28216|Betaproteobacteria,1JZT9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158397_k127_795398_3	1120934.KB894407_gene5094	3.401e-09	71.0	COG2373@1|root,COG2374@1|root,COG5492@1|root,COG2373@2|Bacteria,COG2374@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
SRR25158397_k127_795398_4	1484460.JSWG01000015_gene1033	1.324e-05	59.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG2866@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2866@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,SprB,TSP_3
SRR25158397_k127_795398_0	1254432.SCE1572_45970	2.063e-128	424.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2WNTJ@28221|Deltaproteobacteria,2YZKR@29|Myxococcales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158397_k127_795398_2	272123.Anacy_4370	3.221e-27	116.0	COG1943@1|root,COG1943@2|Bacteria,1G5Y7@1117|Cyanobacteria,1HNSY@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158397_k127_871910_0	379066.GAU_0075	1.482e-278	919.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1ZSMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158397_k127_871910_1	379066.GAU_3665	2.624e-132	429.0	COG1131@1|root,COG1131@2|Bacteria,1ZUJT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158397_k127_871910_5	1144275.COCOR_07749	5.696e-49	183.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria	1224|Proteobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158397_k127_871910_4	321327.CYA_0377	2.633e-56	207.0	COG0142@1|root,COG0142@2|Bacteria,1G1H4@1117|Cyanobacteria,1GZHB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158397_k127_871910_3	1075090.GOAMR_76_00560	1.828e-59	209.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria,4GGRX@85026|Gordoniaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158397_k127_871910_7	380394.Lferr_2593	9.428e-24	112.0	COG2230@1|root,COG2230@2|Bacteria,1QXMG@1224|Proteobacteria,1TEFR@1236|Gammaproteobacteria,2NDTW@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158397_k127_871910_11	1227352.C173_25806	0.0003878	50.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,26UYQ@186822|Paenibacillaceae	91061|Bacilli	MT	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
SRR25158397_k127_871910_6	269796.Rru_A2350	6.133e-28	125.0	COG0500@1|root,COG0500@2|Bacteria,1RD3W@1224|Proteobacteria,2UH9K@28211|Alphaproteobacteria,2JUF7@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158397_k127_871910_9	485918.Cpin_4187	5.193e-08	63.0	COG3409@1|root,COG3409@2|Bacteria,4NQ9D@976|Bacteroidetes	976|Bacteroidetes	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_871910_2	1047013.AQSP01000123_gene1523	6.913e-114	404.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158397_k127_888412_4	204669.Acid345_2692	2.078e-14	80.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_888412_1	338966.Ppro_1311	4.101e-36	158.0	COG0457@1|root,COG0741@1|root,COG1729@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,43U8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
SRR25158397_k127_888412_0	643867.Ftrac_1444	1.168e-38	158.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,47Y1N@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158397_k127_888412_3	1219045.BV98_001829	6.027e-16	85.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2K5QM@204457|Sphingomonadales	204457|Sphingomonadales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158397_k127_888412_2	240015.ACP_1008	5.844e-29	134.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158397_k127_888412_5	1217718.ALOU01000002_gene4722	3.338e-14	78.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
SRR25158397_k127_888412_6	1120954.ATXE01000003_gene585	2.3e-12	71.0	COG0726@1|root,COG4886@1|root,COG5479@1|root,COG0726@2|Bacteria,COG4886@2|Bacteria,COG5479@2|Bacteria,2I6Q0@201174|Actinobacteria,4DX27@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	LGFP,Peptidase_M15_4
SRR25158397_k127_904_3	945713.IALB_1137	1.053e-30	122.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158397_k127_904_1	204669.Acid345_2530	6.078e-114	372.0	COG0330@1|root,COG0330@2|Bacteria,3Y33E@57723|Acidobacteria,2JHPX@204432|Acidobacteriia	204432|Acidobacteriia	O	SMART band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158397_k127_904_0	1519464.HY22_07105	3.402e-272	865.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158397_k127_904_2	1047013.AQSP01000132_gene1707	1.171e-39	156.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158397_k127_929161_5	1242864.D187_006584	5.715e-33	141.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria	1224|Proteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158397_k127_929161_3	1223523.H340_13716	6.334e-91	312.0	COG4447@1|root,COG4447@2|Bacteria,2IGT5@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_929161_2	448385.sce6364	4.194e-108	390.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CarboxypepD_reg,Cohesin
SRR25158397_k127_929161_1	204669.Acid345_2229	1.107e-113	403.0	COG0308@1|root,COG0308@2|Bacteria,3Y7E9@57723|Acidobacteria,2JMED@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158397_k127_929161_7	926560.KE387027_gene824	2.443e-20	100.0	COG2318@1|root,COG2318@2|Bacteria,1WNBD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158397_k127_929161_0	1297742.A176_05098	1.133e-162	533.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2YUBN@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158397_k127_929161_4	1124983.PFLCHA0_c21960	1.46e-80	274.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1YNDV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	C	Iron-sulfur cluster-binding domain	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158397_k127_937878_1	1499967.BAYZ01000004_gene4922	3.963e-58	221.0	28M0D@1|root,2ZAFE@2|Bacteria	2|Bacteria	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
SRR25158397_k127_937878_6	944481.JAFP01000001_gene802	0.0002878	53.0	2DU4A@1|root,33NW4@2|Bacteria,1R1RZ@1224|Proteobacteria,43DAW@68525|delta/epsilon subdivisions,2X8GZ@28221|Deltaproteobacteria,2M7E2@213113|Desulfurellales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_937878_5	58123.JOFJ01000001_gene2995	6.223e-20	93.0	2E37T@1|root,32Y7G@2|Bacteria,2GQH5@201174|Actinobacteria,4EJZ1@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158397_k127_937878_4	204669.Acid345_1886	3.74e-25	110.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CD225,DUF4339,zinc_ribbon_2
SRR25158397_k127_937878_2	1123253.AUBD01000005_gene61	5.05e-58	207.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales	135614|Xanthomonadales	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158397_k127_937878_3	1283300.ATXB01000001_gene922	1.789e-52	188.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XF3J@135618|Methylococcales	135618|Methylococcales	C	TIGRFAM SUF system FeS	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158397_k127_937878_0	1042209.HK44_007330	3.654e-124	402.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1YMXS@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Cysteine desulfurase	sufS	-	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
SRR25158397_k127_940349_2	1492737.FEM08_06560	1.447e-95	319.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,1I2BC@117743|Flavobacteriia,2NTPT@237|Flavobacterium	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158397_k127_940349_7	378806.STAUR_3906	6.414e-48	199.0	COG3746@1|root,COG3746@2|Bacteria,1PBWD@1224|Proteobacteria,433TT@68525|delta/epsilon subdivisions,2X3F8@28221|Deltaproteobacteria,2YVU2@29|Myxococcales	28221|Deltaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_940349_6	1382306.JNIM01000001_gene1232	1.903e-54	220.0	COG5002@1|root,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158397_k127_940349_4	592015.HMPREF1705_01104	2.678e-75	260.0	COG1694@1|root,COG3956@2|Bacteria,3TAH9@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM MazG family protein	-	-	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158397_k127_940349_8	1121362.A605_14055	5.724e-13	75.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,22PAT@1653|Corynebacteriaceae	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158397_k127_940349_5	861299.J421_2443	8.533e-73	253.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158397_k127_940349_0	555079.Toce_1475	5.487e-254	793.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,42FI5@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158397_k127_940349_3	1056512.D515_04309	5.414e-84	291.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1XSEJ@135623|Vibrionales	135623|Vibrionales	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158397_k127_940349_1	204669.Acid345_3116	1.248e-100	355.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158397_k127_954690_6	1121013.P873_09660	9.235e-26	119.0	COG2373@1|root,COG4625@1|root,COG2373@2|Bacteria,COG4625@2|Bacteria,1RDX6@1224|Proteobacteria,1S53I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM outer membrane autotransporter barrel	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
SRR25158397_k127_954690_0	1384056.N787_07955	2.334e-79	295.0	COG0790@1|root,COG4249@1|root,COG0790@2|Bacteria,COG4249@2|Bacteria,1MWPA@1224|Proteobacteria,1RRKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	FOG TPR repeat SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Peptidase_C14,Sel1
SRR25158397_k127_954690_4	391625.PPSIR1_07842	5.947e-48	198.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158397_k127_954690_7	1308866.J416_08262	8.462e-17	95.0	COG4916@1|root,COG4916@2|Bacteria,1V3JG@1239|Firmicutes,4HHRM@91061|Bacilli	91061|Bacilli	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158397_k127_954690_3	326427.Cagg_0357	3.99e-51	206.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	32061|Chloroflexia	NU	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_10,TPR_12,TPR_16,TPR_7
SRR25158397_k127_954690_2	1110697.NCAST_08_00260	1.15e-54	216.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria,4FXD4@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
SRR25158397_k127_954690_5	55952.BU52_28500	4.588e-26	117.0	28NF4@1|root,2ZBHH@2|Bacteria,2IBXR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_954690_1	391625.PPSIR1_30385	1.446e-60	214.0	COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,43APS@68525|delta/epsilon subdivisions,2X63H@28221|Deltaproteobacteria,2YVYC@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158397_k127_980985_3	1121428.DESHY_60099___1	1.124e-50	187.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158397_k127_980985_5	313612.L8106_10327	7.347e-27	115.0	COG2402@1|root,COG2402@2|Bacteria,1G7JM@1117|Cyanobacteria,1HHIB@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158397_k127_980985_1	215803.DB30_0789	1.018e-75	263.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158397_k127_980985_2	1461580.CCAS010000022_gene2372	6.464e-62	223.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1ZBZD@1386|Bacillus	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158397_k127_980985_6	1123376.AUIU01000011_gene1046	3.904e-11	65.0	COG1826@1|root,COG1826@2|Bacteria,3J1A4@40117|Nitrospirae	40117|Nitrospirae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158397_k127_980985_0	1118054.CAGW01000056_gene2118	1.513e-187	628.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,26QTI@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158397_k127_980985_4	324602.Caur_1089	2.289e-36	160.0	COG1572@1|root,COG1572@2|Bacteria,2G7MU@200795|Chloroflexi,374XB@32061|Chloroflexia	32061|Chloroflexia	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
SRR25158397_k127_994406_22	349521.HCH_00233	0.0005282	50.0	2E6S7@1|root,331C9@2|Bacteria,1NP0T@1224|Proteobacteria,1SW90@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_994406_17	1242864.D187_006629	1.049e-25	119.0	COG0760@1|root,COG0760@2|Bacteria,1RKBZ@1224|Proteobacteria,42SAP@68525|delta/epsilon subdivisions,2WPWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
SRR25158397_k127_994406_21	1225785.CM001983_gene3331	4.083e-07	61.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,2JECF@204037|Dickeya	1236|Gammaproteobacteria	O	peptidyl-prolyl cis-trans isomerase	ppiC	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
SRR25158397_k127_994406_7	1104324.P186_0659	1.657e-68	240.0	COG0846@1|root,arCOG04248@2157|Archaea,2XQBQ@28889|Crenarchaeota	28889|Crenarchaeota	K	form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158397_k127_994406_10	1536774.H70357_27815	2.285e-46	179.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,26S1K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158397_k127_994406_3	338966.Ppro_1335	9.185e-86	297.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,43UA0@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
SRR25158397_k127_994406_9	1120973.AQXL01000128_gene2783	5.337e-48	181.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,279ZC@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158397_k127_994406_15	37659.JNLN01000001_gene272	3.078e-29	131.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,36H7U@31979|Clostridiaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158397_k127_994406_14	1042375.AFPL01000030_gene561	1.167e-33	144.0	COG0500@1|root,COG2226@2|Bacteria,1MZ4M@1224|Proteobacteria,1RZK0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158397_k127_994406_12	1158345.JNLL01000001_gene1990	1.411e-35	142.0	COG0359@1|root,COG0359@2|Bacteria,2G44E@200783|Aquificae	200783|Aquificae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158397_k127_994406_16	1267533.KB906734_gene4260	1.879e-26	112.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria,2JN1Z@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S18	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158397_k127_994406_20	2325.TKV_c24610	1.609e-20	98.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,42GUD@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158397_k127_994406_0	525897.Dbac_3330	2.525e-113	375.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,42MA1@68525|delta/epsilon subdivisions,2WMVY@28221|Deltaproteobacteria,2MGKV@213115|Desulfovibrionales	28221|Deltaproteobacteria	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158397_k127_994406_4	497964.CfE428DRAFT_2977	2.206e-83	296.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158397_k127_994406_6	380749.HY04AAS1_0509	2.369e-74	257.0	COG1028@1|root,COG1028@2|Bacteria,2G3IV@200783|Aquificae	200783|Aquificae	IQ	Short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158397_k127_994406_2	398767.Glov_1938	1.042e-100	339.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158397_k127_994406_1	370438.PTH_1746	2.849e-103	347.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158397_k127_994406_18	1267533.KB906734_gene4285	2.179e-21	95.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JNN2@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	-	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158397_k127_994406_19	644282.Deba_2394	1.117e-20	99.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158397_k127_994406_8	479434.Sthe_0904	4.578e-53	213.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_994406_11	479434.Sthe_0904	2.259e-43	171.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158397_k127_994406_13	1380390.JIAT01000014_gene6079	1.792e-34	145.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CQTJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158397_k127_994406_5	397278.JOJN01000001_gene2741	2.328e-81	276.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4DPHV@85009|Propionibacteriales	201174|Actinobacteria	Q	Domain of unknown function (DUF2437)	fahA	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158397_k127_99456_3	1121920.AUAU01000015_gene1127	1.151e-69	263.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
SRR25158397_k127_99456_8	983917.RGE_32210	1.175e-16	93.0	COG2885@1|root,COG2885@2|Bacteria,1PH1G@1224|Proteobacteria,2W308@28216|Betaproteobacteria	28216|Betaproteobacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
SRR25158397_k127_99456_12	502025.Hoch_6692	0.0001924	52.0	COG2823@1|root,COG2823@2|Bacteria,1PY9X@1224|Proteobacteria,42YAD@68525|delta/epsilon subdivisions,2WU1C@28221|Deltaproteobacteria,2Z27W@29|Myxococcales	28221|Deltaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158397_k127_99456_1	1049564.TevJSym_bl00220	2.398e-106	366.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1J50B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158397_k127_99456_9	1380394.JADL01000001_gene2153	1.755e-13	76.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,2JU8R@204441|Rhodospirillales	204441|Rhodospirillales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158397_k127_99456_4	1278073.MYSTI_03082	1.141e-50	200.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
SRR25158397_k127_99456_5	1123073.KB899243_gene666	2.326e-45	176.0	2CX7C@1|root,32T1D@2|Bacteria,1N2N3@1224|Proteobacteria,1S4YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158397_k127_99456_7	861299.J421_4133	3.255e-37	147.0	2CB8S@1|root,30PE6@2|Bacteria,1ZV1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
SRR25158397_k127_99456_6	204669.Acid345_2902	3.811e-39	152.0	COG2197@1|root,COG2197@2|Bacteria,3Y60I@57723|Acidobacteria,2JKWI@204432|Acidobacteriia	204432|Acidobacteriia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158397_k127_99456_0	338963.Pcar_2345	2.442e-157	509.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158397_k127_99456_2	1499967.BAYZ01000008_gene5423	1.92e-105	368.0	COG5000@1|root,COG5000@2|Bacteria,2NQRV@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	ntrY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158397_k127_99456_10	177437.HRM2_11180	1.73e-06	57.0	29GM5@1|root,303IT@2|Bacteria,1RG3T@1224|Proteobacteria,42RUX@68525|delta/epsilon subdivisions,2WNMJ@28221|Deltaproteobacteria,2MJY1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
SRR25158397_k127_998422_2	1121468.AUBR01000050_gene2015	1.641e-26	117.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158397_k127_998422_3	204669.Acid345_3258	3.199e-19	90.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158397_k127_998422_1	1313301.AUGC01000005_gene235	3.959e-78	271.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158397_k127_998422_0	562970.Btus_0655	2.194e-92	314.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,4HAAQ@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator (AsnC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
## 4441 queries scanned
## Total time (seconds): 6.726758241653442
## Rate: 660.20 q/s