## Mon Dec 15 12:23:11 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158416_bin.7.fa -m mmseqs --itype genome -o SRR25158416_bin.7 --output_dir /data/result/bins/wyx/egg/SRR25158416_bin.7 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158416_k127_1064077_0	1380393.JHVP01000003_gene1268	1.897e-160	518.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_1064077_1	477641.MODMU_1794	8.87e-137	449.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_1064077_2	1380386.JIAW01000015_gene6547	3.127e-51	183.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_1074157_5	1146883.BLASA_1899	2.375e-42	168.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4ESK1@85013|Frankiales	201174|Actinobacteria	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
SRR25158416_k127_1074157_6	1229780.BN381_450012	6.128e-21	96.0	COG1143@1|root,COG1143@2|Bacteria,2H4NQ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
SRR25158416_k127_1074157_2	1313172.YM304_04010	2.314e-115	378.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158416_k127_1074157_3	1313172.YM304_04020	4.924e-57	209.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158416_k127_1074157_4	1229780.BN381_450009	3.449e-47	184.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158416_k127_1074157_7	1313172.YM304_04040	1.859e-08	66.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158416_k127_1074157_0	867903.ThesuDRAFT_00610	4.965e-157	506.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3WCHX@538999|Clostridiales incertae sedis	186801|Clostridia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158416_k127_1074157_1	471852.Tcur_4437	4.622e-124	406.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4EHK2@85012|Streptosporangiales	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158416_k127_1076086_1	235985.BBPN01000013_gene6598	1.313e-63	247.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158416_k127_1076086_0	1037409.BJ6T_56240	4.766e-159	512.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158416_k127_1076086_2	485913.Krac_6021	1.184e-59	222.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_1076086_3	258533.BN977_03375	6.991e-31	134.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_1093035_3	1304878.AUGD01000014_gene3098	5.074e-19	94.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,3JRM1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator, winged helix family	ctrA	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_1093035_2	1246995.AFR_07535	2.88e-76	273.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4D9U9@85008|Micromonosporales	201174|Actinobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158416_k127_1093035_1	1121877.JQKF01000001_gene1378	2.201e-85	287.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158416_k127_1093035_0	479433.Caci_7293	8.671e-186	588.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158416_k127_1120995_2	1210884.HG799462_gene8895	1.539e-69	259.0	COG3852@1|root,COG3852@2|Bacteria,2J4Y6@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158416_k127_1120995_1	1121272.KB903257_gene5483	1.95e-87	295.0	2EWQK@1|root,33Q2D@2|Bacteria,2IJ4T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1120995_0	471852.Tcur_4497	7.669e-132	431.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4EI4P@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158416_k127_1120995_3	309801.trd_1590	5.826e-47	183.0	COG1565@1|root,COG1565@2|Bacteria,2G8NS@200795|Chloroflexi,27Y3B@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158416_k127_1136140_0	710696.Intca_0412	1.873e-132	435.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4FERS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158416_k127_1136140_1	1121364.ATVG01000001_gene854	7.52e-34	140.0	COG0036@1|root,COG0144@1|root,COG0036@2|Bacteria,COG0144@2|Bacteria,2GM21@201174|Actinobacteria,22KE8@1653|Corynebacteriaceae	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158416_k127_1165534_7	370438.PTH_0002	2.788e-29	132.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,2611U@186807|Peptococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158416_k127_1165534_12	204669.Acid345_0509	2.012e-11	74.0	COG0745@1|root,COG0745@2|Bacteria,3Y4R4@57723|Acidobacteria,2JJBD@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_1165534_11	1206737.BAGF01000148_gene5973	7.869e-12	71.0	2EEUC@1|root,338MW@2|Bacteria,2IQC9@201174|Actinobacteria,4G316@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbC
SRR25158416_k127_1165534_5	479433.Caci_6847	2.13e-37	158.0	COG3087@1|root,COG3087@2|Bacteria,2IBKJ@201174|Actinobacteria	201174|Actinobacteria	D	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1165534_3	1089545.KB913037_gene780	1.429e-60	232.0	28HZQ@1|root,2Z84P@2|Bacteria,2H0F4@201174|Actinobacteria,4DYNP@85010|Pseudonocardiales	201174|Actinobacteria	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
SRR25158416_k127_1165534_0	1463856.JOHY01000035_gene1862	5.783e-182	594.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
SRR25158416_k127_1165534_9	105420.BBPO01000057_gene3498	4.297e-13	80.0	COG0741@1|root,COG0741@2|Bacteria,2HKTH@201174|Actinobacteria,2NFDX@228398|Streptacidiphilus	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1165534_1	1449346.JQMO01000003_gene6673	2.97e-179	595.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria,2M5EG@2063|Kitasatospora	201174|Actinobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR25158416_k127_1165534_4	1206731.BAGB01000162_gene7867	2.367e-47	181.0	2ECZS@1|root,336WS@2|Bacteria,2HCMY@201174|Actinobacteria,4FX3N@85025|Nocardiaceae	201174|Actinobacteria	S	Replication-relaxation	-	-	-	-	-	-	-	-	-	-	-	-	Replic_Relax
SRR25158416_k127_1165534_13	378806.STAUR_6088	1.14e-06	54.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PocR
SRR25158416_k127_1165534_6	1194165.CAJF01000005_gene2318	9.796e-35	147.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4FTSE@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1165534_10	365528.KB891280_gene1789	9.113e-13	76.0	2DBDD@1|root,2Z8JQ@2|Bacteria,2IE96@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1165534_2	1054860.KB913030_gene5738	4.448e-112	372.0	COG3673@1|root,COG3673@2|Bacteria,2ID7N@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
SRR25158416_k127_1231270_0	1121272.KB903292_gene3880	1.878e-103	339.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4D9C4@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1231270_2	479434.Sthe_1268	2.298e-13	79.0	COG4454@1|root,COG4454@2|Bacteria,2GBEQ@200795|Chloroflexi,27Z6N@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1231270_1	926569.ANT_12920	2.221e-25	113.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
SRR25158416_k127_1232289_5	1380390.JIAT01000010_gene3850	1.355e-22	104.0	COG2114@1|root,COG2114@2|Bacteria,2HSA4@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	cya	GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158416_k127_1232289_3	525904.Tter_0136	1.053e-36	152.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158416_k127_1232289_0	1223545.GS4_23_00090	3.487e-61	214.0	2ECJT@1|root,336HX@2|Bacteria,2IKEF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1232289_2	485913.Krac_0221	4.204e-42	170.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1232289_1	710686.Mycsm_06153	6.125e-50	194.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,23D0V@1762|Mycobacteriaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_1232289_4	468556.AQYG01000045_gene1908	7.321e-29	117.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria,4GERC@85026|Gordoniaceae	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158416_k127_1234393_0	35754.JNYJ01000019_gene80	1.859e-95	333.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12
SRR25158416_k127_1234393_1	1122182.KB903814_gene3062	7.24e-72	258.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4DC3S@85008|Micromonosporales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158416_k127_1234393_2	1121272.KB903290_gene4484	5.318e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4DEWR@85008|Micromonosporales	201174|Actinobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_1236585_0	1146883.BLASA_3911	4.512e-268	840.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4EXCP@85013|Frankiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase large subunit	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158416_k127_1281258_7	292459.STH1455	1.833e-23	109.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158416_k127_1281258_6	485914.Hmuk_2406	1.548e-23	108.0	COG1254@1|root,arCOG01674@2157|Archaea,2XYT5@28890|Euryarchaeota,23WSX@183963|Halobacteria	183963|Halobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158416_k127_1281258_3	1122939.ATUD01000022_gene3674	1.727e-42	169.0	2EBVK@1|root,335V0@2|Bacteria,2GYP5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1281258_1	696281.Desru_2500	1.311e-58	221.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_1281258_0	2002.JOEQ01000012_gene5618	1.673e-71	254.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4EGGX@85012|Streptosporangiales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158416_k127_1281258_8	867903.ThesuDRAFT_00311	3.047e-20	91.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WCP9@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158416_k127_1281258_4	710696.Intca_2313	5.227e-34	137.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4FFUV@85021|Intrasporangiaceae	201174|Actinobacteria	S	metal-binding protein	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158416_k127_1281258_5	469383.Cwoe_3698	2.799e-31	129.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1281258_2	1996.JOFO01000037_gene6557	1.813e-57	204.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4EJ3N@85012|Streptosporangiales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158416_k127_1296351_1	756272.Plabr_1996	1.802e-81	280.0	COG0403@1|root,COG0403@2|Bacteria,2IXNG@203682|Planctomycetes	203682|Planctomycetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158416_k127_1296351_0	1033743.CAES01000045_gene259	1.012e-171	552.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,26RUP@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158416_k127_1312565_15	106370.Francci3_0978	3.328e-18	88.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_1312565_0	1122939.ATUD01000001_gene60	3.459e-133	441.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4CQZB@84995|Rubrobacteria	84995|Rubrobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_1312565_9	1229780.BN381_10102	1.207e-39	163.0	2DZ4T@1|root,34CFG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1312565_10	882083.SacmaDRAFT_2530	2.925e-34	143.0	2EA1Q@1|root,33470@2|Bacteria,2HCTN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxD
SRR25158416_k127_1312565_2	882083.SacmaDRAFT_2526	2.873e-110	368.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	moeX	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158416_k127_1312565_3	1122138.AQUZ01000023_gene7861	6.377e-109	358.0	COG3221@1|root,COG3221@2|Bacteria,2GK9B@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
SRR25158416_k127_1312565_1	1108045.GORHZ_055_00140	3.367e-130	437.0	COG1960@1|root,COG1960@2|Bacteria,2GZNN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE16	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_1312565_6	1380393.JHVP01000007_gene4330	4.949e-86	308.0	28KB1@1|root,2Z9Y5@2|Bacteria,2GM37@201174|Actinobacteria,4EWN1@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1312565_8	1283299.AUKG01000001_gene3462	5.463e-63	223.0	COG3222@1|root,COG3222@2|Bacteria,2GN3B@201174|Actinobacteria,4CT18@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064
SRR25158416_k127_1312565_7	1283299.AUKG01000001_gene3463	3.782e-85	287.0	COG1216@1|root,COG1216@2|Bacteria,2HFMY@201174|Actinobacteria,4CSCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_1312565_16	1121380.JNIW01000047_gene51	1.245e-17	85.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158416_k127_1312565_17	1089550.ATTH01000002_gene47	2.087e-16	84.0	COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PA26 p53-induced protein (sestrin)	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158416_k127_1312565_19	42256.RradSPS_2934	6.324e-06	55.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_1312565_11	290399.Arth_2008	7.505e-31	125.0	COG0346@1|root,COG0346@2|Bacteria,2IRQX@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1312565_14	573413.Spirs_3837	1.457e-19	90.0	COG0604@1|root,COG0604@2|Bacteria,2JAG1@203691|Spirochaetes	203691|Spirochaetes	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2
SRR25158416_k127_1312565_12	358681.BBR47_14480	3.928e-24	104.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,274FR@186822|Paenibacillaceae	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_1312565_18	574376.BAMA_14970	6.705e-09	57.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_1312565_20	1449044.JMLE01000012_gene3086	0.0003084	50.0	COG2197@1|root,COG2197@2|Bacteria,2GN29@201174|Actinobacteria,1WCHG@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	2.7.11.1	ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	GerE,Response_reg
SRR25158416_k127_1312565_13	1089545.KB913037_gene8413	2.547e-22	103.0	COG2197@1|root,COG2197@2|Bacteria,2GYMP@201174|Actinobacteria,4E2HE@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_1312565_5	1068980.ARVW01000001_gene5080	5.723e-99	330.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4E36H@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K21209	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	Abhydrolase_6
SRR25158416_k127_1312565_4	1047013.AQSP01000017_gene1088	3.115e-108	357.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_132031_0	1122622.ATWJ01000002_gene800	7.253e-33	136.0	COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_132031_1	497321.C664_14489	2.407e-13	79.0	COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2VHDB@28216|Betaproteobacteria,2KW1U@206389|Rhodocyclales	206389|Rhodocyclales	O	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1343461_0	1128421.JAGA01000002_gene1688	2.004e-52	195.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158416_k127_1343461_1	258533.BN977_06087	1.385e-44	167.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,2398U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158416_k127_1350268_4	1089552.KI911559_gene1300	2.074e-42	173.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,2TUNH@28211|Alphaproteobacteria,2JRQ5@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158416_k127_1350268_2	1122939.ATUD01000005_gene2772	1.045e-110	369.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4CP6Z@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158416_k127_1350268_3	883156.HMPREF9282_00218	4.253e-43	166.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4H2ZU@909932|Negativicutes	909932|Negativicutes	S	domain protein	gloB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_1350268_1	997346.HMPREF9374_1616	7.321e-117	403.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,27B8A@186824|Thermoactinomycetaceae	91061|Bacilli	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His
SRR25158416_k127_1350268_0	1125863.JAFN01000001_gene2870	1.746e-209	667.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158416_k127_136255_4	604331.AUHY01000031_gene2367	8.086e-13	75.0	COG1426@1|root,COG1426@2|Bacteria,1WI06@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PEGA domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25,PEGA
SRR25158416_k127_136255_3	1123057.P872_21170	4.404e-43	167.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	tauX	-	-	ko:K07255,ko:K21700	ko00430,map00430	-	R01685	RC00062	ko00000,ko00001,ko01000	-	-	-	SnoaL_2
SRR25158416_k127_136255_2	1382356.JQMP01000003_gene1548	2.108e-48	177.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi,27Y9T@189775|Thermomicrobia	189775|Thermomicrobia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158416_k127_136255_1	298655.KI912266_gene5504	5.336e-110	369.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4ERQF@85013|Frankiales	201174|Actinobacteria	H	Mur ligase, middle domain protein	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_136255_0	645991.Sgly_2480	6.769e-164	534.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158416_k127_1384297_6	926569.ANT_25700	1.524e-18	87.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158416_k127_1384297_4	1121445.ATUZ01000016_gene2481	1.321e-29	125.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_1384297_7	395961.Cyan7425_4410	1.009e-09	69.0	COG0745@1|root,COG0745@2|Bacteria,1GFMN@1117|Cyanobacteria	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_1384297_2	1280950.HJO_08262	4.209e-65	234.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1MVJY@1224|Proteobacteria,2U1SU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2203 FOG GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2
SRR25158416_k127_1384297_1	1238182.C882_0684	5.703e-109	368.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales	204441|Rhodospirillales	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158416_k127_1384297_0	1382356.JQMP01000004_gene506	8.103e-133	446.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158416_k127_1384297_3	525904.Tter_1944	7.97e-45	173.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158416_k127_1384297_5	479432.Sros_6686	4.508e-23	101.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4EJVT@85012|Streptosporangiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_1388151_2	1380370.JIBA01000015_gene98	1.416e-70	248.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158416_k127_1388151_1	357808.RoseRS_3808	5.488e-101	354.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,374X0@32061|Chloroflexia	32061|Chloroflexia	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158416_k127_1388151_4	356851.JOAN01000035_gene1958	1.61e-27	121.0	COG2335@1|root,COG2335@2|Bacteria,2GJC2@201174|Actinobacteria,4DCPB@85008|Micromonosporales	201174|Actinobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158416_k127_1388151_3	319795.Dgeo_2617	6.201e-43	168.0	COG1414@1|root,COG1414@2|Bacteria,1WIBR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158416_k127_1388151_0	356851.JOAN01000035_gene1957	4.598e-176	582.0	COG2866@1|root,COG2866@2|Bacteria,2GJ8D@201174|Actinobacteria,4D9AF@85008|Micromonosporales	201174|Actinobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_1388151_5	1123508.JH636450_gene7219	6.527e-22	112.0	COG1404@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,2IZWN@203682|Planctomycetes	203682|Planctomycetes	Q	HemY domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1388151_6	1123024.AUII01000004_gene1588	4.375e-09	58.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4DXN1@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_1392903_0	710111.FraQA3DRAFT_4954	9.882e-106	356.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4EUS9@85013|Frankiales	201174|Actinobacteria	S	low temperature requirement A	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158416_k127_1392903_1	56110.Oscil6304_1825	5.722e-44	172.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158416_k127_1392903_2	926569.ANT_25530	5.061e-16	87.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158416_k127_1397478_4	1111479.AXAR01000001_gene146	9.247e-22	100.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HD89@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_1397478_1	1121468.AUBR01000017_gene2371	2.465e-194	617.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158416_k127_1397478_3	1869.MB27_22615	1.477e-24	107.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4DEPX@85008|Micromonosporales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158416_k127_1397478_0	656024.FsymDg_3774	2.907e-210	676.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4ES5B@85013|Frankiales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158416_k127_1397478_2	562970.Btus_1096	1.374e-37	145.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,278QW@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158416_k127_1450333_3	1121946.AUAX01000017_gene4915	6.843e-150	530.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158416_k127_1450333_11	429009.Adeg_1311	2.079e-46	195.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_1450333_10	526225.Gobs_0857	2.026e-54	221.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2I39H@201174|Actinobacteria,4EXCD@85013|Frankiales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TIR_2,TPR_10,TPR_12
SRR25158416_k127_1450333_17	234267.Acid_3226	0.0007277	51.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_1450333_15	1519464.HY22_02500	4.094e-16	89.0	29VUZ@1|root,30HCS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158416_k127_1450333_12	1211815.CBYP010000006_gene276	1.79e-37	151.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1450333_16	644283.Micau_0068	4.117e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,2GP2X@201174|Actinobacteria,4DJ2A@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_1450333_14	1122622.ATWJ01000009_gene3140	2.181e-16	90.0	2BCR7@1|root,326BP@2|Bacteria,2HBS1@201174|Actinobacteria,4FJTY@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1450333_9	1380391.JIAS01000010_gene3891	2.106e-67	252.0	COG0823@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2931@2|Bacteria,1R7MY@1224|Proteobacteria,2U3HC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158416_k127_1450333_7	67352.JODS01000001_gene476	5.253e-99	341.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158416_k127_1450333_2	469383.Cwoe_5590	1.806e-161	545.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I3CX@201174|Actinobacteria	2|Bacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158416_k127_1450333_1	469383.Cwoe_5590	7.102e-166	557.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I3CX@201174|Actinobacteria	2|Bacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158416_k127_1450333_4	446470.Snas_0537	1.777e-149	509.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
SRR25158416_k127_1450333_13	1463920.JOGB01000064_gene4352	2.131e-16	94.0	COG2931@1|root,COG3291@1|root,COG4409@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	ASH,Big_3_2,F5_F8_type_C,HemolysinCabind,SBBP
SRR25158416_k127_1450333_8	1211815.CBYP010000053_gene2085	3.805e-75	280.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158416_k127_1450333_6	67352.JODS01000001_gene476	6.364e-121	408.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158416_k127_1450333_5	497964.CfE428DRAFT_0631	6.144e-149	506.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158416_k127_1450333_0	1283299.AUKG01000001_gene2437	2.263e-177	597.0	COG3899@1|root,COG3899@2|Bacteria,2HFRA@201174|Actinobacteria,4CR76@84995|Rubrobacteria	84995|Rubrobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158416_k127_1459670_6	485913.Krac_6681	3.635e-11	64.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_1459670_1	1122622.ATWJ01000014_gene282	1.825e-76	264.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4FFI1@85021|Intrasporangiaceae	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158416_k127_1459670_4	479435.Kfla_1844	2.988e-53	201.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4DPGW@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158416_k127_1459670_0	1125863.JAFN01000001_gene2879	1.212e-84	301.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,42NEX@68525|delta/epsilon subdivisions,2WJ1Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158416_k127_1459670_3	1121430.JMLG01000002_gene1035	9.24e-54	196.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158416_k127_1459670_10	485913.Krac_9827	1.22e-07	59.0	arCOG13241@1|root,2ZEFN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1459670_7	335283.Neut_2099	1.047e-10	69.0	COG4244@1|root,COG4244@2|Bacteria,1NJGN@1224|Proteobacteria,2VYSI@28216|Betaproteobacteria,37354@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158416_k127_1459670_2	383372.Rcas_2972	1.127e-74	261.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,376KK@32061|Chloroflexia	32061|Chloroflexia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_1459670_5	756883.Halar_1947	5.155e-15	86.0	COG0702@1|root,arCOG03015@2157|Archaea	2157|Archaea	GM	NAD-dependent epimerase dehydratase	nolA	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRR25158416_k127_1459670_12	365528.KB891170_gene5180	1.286e-06	60.0	2EI4A@1|root,33BVN@2|Bacteria,2GX45@201174|Actinobacteria,4ETJR@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1459670_11	1211815.CBYP010000062_gene3178	8.066e-07	51.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158416_k127_1459670_9	525904.Tter_2084	6.636e-08	55.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	CBS
SRR25158416_k127_1459670_8	1157490.EL26_00850	5.833e-10	72.0	2EFPZ@1|root,339G0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1459995_2	1121866.AUGK01000004_gene27	5.696e-78	269.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CUK7@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158416_k127_1459995_6	871968.DESME_01475	9.567e-35	136.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,2621D@186807|Peptococcaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158416_k127_1459995_4	457570.Nther_0198	1.744e-44	165.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158416_k127_1459995_0	479433.Caci_0934	1.108e-133	430.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158416_k127_1459995_7	1292373.H640_00255	4.997e-26	115.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4DR9N@85009|Propionibacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158416_k127_1459995_3	1229780.BN381_450096	8.523e-54	209.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,3UWGH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158416_k127_1459995_1	58123.JOFJ01000024_gene3502	4.682e-83	280.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4EIEQ@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158416_k127_1459995_5	267747.PPA1865	1.048e-41	156.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4DQJR@85009|Propionibacteriales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158416_k127_1459995_8	656024.FsymDg_3963	4.755e-24	101.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158416_k127_1541378_12	525904.Tter_0232	3.417e-26	125.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158416_k127_1541378_14	696369.KI912183_gene1207	7.118e-17	94.0	COG0500@1|root,COG0500@2|Bacteria,1VJS9@1239|Firmicutes,24TBM@186801|Clostridia	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_1541378_15	525904.Tter_0487	1.95e-10	74.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158416_k127_1541378_1	644966.Tmar_1967	2.16e-106	356.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3WCW3@538999|Clostridiales incertae sedis	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158416_k127_1541378_5	1449126.JQKL01000003_gene1756	3.371e-79	286.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158416_k127_1541378_7	1128421.JAGA01000002_gene1294	1.891e-68	249.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_1541378_2	1229780.BN381_80108	4.685e-103	340.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,3UW73@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158416_k127_1541378_8	1246995.AFR_05850	6.137e-54	201.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4D9UH@85008|Micromonosporales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158416_k127_1541378_9	309801.trd_0238	2.477e-46	171.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi,27YCP@189775|Thermomicrobia	189775|Thermomicrobia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158416_k127_1541378_13	1121939.L861_10705	2.635e-22	102.0	COG3832@1|root,COG3832@2|Bacteria,1RICZ@1224|Proteobacteria,1S9XH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158416_k127_1541378_0	455632.SGR_3841	4.89e-115	383.0	COG1520@1|root,COG1520@2|Bacteria,2GW3X@201174|Actinobacteria	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158416_k127_1541378_11	1122611.KB903946_gene777	1.678e-27	128.0	COG5640@1|root,COG5640@2|Bacteria,2IB3X@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158416_k127_1541378_6	1463853.JOHW01000008_gene818	4.604e-75	259.0	COG0491@1|root,COG0491@2|Bacteria,2GJ6X@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_1541378_4	388413.ALPR1_05140	1.788e-83	289.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158416_k127_1541378_10	1121875.KB907547_gene3443	4.7e-30	123.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
SRR25158416_k127_1541378_3	675635.Psed_1534	1.579e-92	314.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158416_k127_1562179_0	365528.KB891252_gene5627	5.644e-81	282.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4ERU8@85013|Frankiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158416_k127_1562179_4	985255.APHJ01000031_gene2757	1.366e-18	100.0	COG0823@1|root,COG2304@1|root,COG4254@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG4254@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2P5SV@244698|Gillisia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
SRR25158416_k127_1562179_1	477641.MODMU_4336	7.319e-53	192.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria,4EX78@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_1562179_5	1122138.AQUZ01000002_gene1963	3.895e-15	84.0	COG5662@1|root,COG5662@2|Bacteria,2INVC@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_1562179_2	1229780.BN381_160023	4.125e-35	138.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,3UXDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158416_k127_1562179_3	369723.Strop_0390	1.566e-22	104.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria,4D9WR@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158416_k127_156642_1	1122611.KB903949_gene6521	3.254e-24	114.0	COG2936@1|root,COG2936@2|Bacteria,2GJ2K@201174|Actinobacteria,4EGZ2@85012|Streptosporangiales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
SRR25158416_k127_156642_0	1122925.KB895396_gene1790	1.852e-70	243.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,26RBI@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158416_k127_1587665_5	269799.Gmet_2673	1.806e-09	60.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,43U1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158416_k127_1587665_0	469371.Tbis_1363	7.452e-161	515.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4DXAM@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158416_k127_1587665_2	1136417.AZWE01000003_gene3339	4.179e-61	233.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4DA4R@85008|Micromonosporales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_1587665_3	1122609.AUGT01000002_gene4011	6.465e-46	171.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4DQIB@85009|Propionibacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158416_k127_1587665_1	867903.ThesuDRAFT_00336	6.141e-71	253.0	COG0223@1|root,COG0242@1|root,COG0223@2|Bacteria,COG0242@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WCIU@538999|Clostridiales incertae sedis	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N,Pep_deformylase
SRR25158416_k127_1587665_6	637390.AFOH01000137_gene1760	9.229e-06	49.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,2NCX8@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158416_k127_1587665_4	1111730.ATTM01000008_gene825	8.049e-12	69.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia,2NTCA@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158416_k127_162242_0	656024.FsymDg_4537	2.686e-63	230.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4ERF4@85013|Frankiales	201174|Actinobacteria	KLT	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158416_k127_162242_1	1048339.KB913029_gene1652	1.837e-13	83.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4ESX8@85013|Frankiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_164006_2	1068978.AMETH_0818	7.445e-22	97.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4DYJ6@85010|Pseudonocardiales	201174|Actinobacteria	F	TIGRFAM pyrimidine-nucleoside phosphorylase	deoA	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158416_k127_164006_0	1121430.JMLG01000003_gene532	2.525e-144	482.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158416_k127_164006_3	1125863.JAFN01000001_gene3090	3.939e-16	82.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	RNA polymerase-binding protein DksA	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158416_k127_164006_1	408672.NBCG_02708	5.662e-60	212.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DNSC@85009|Propionibacteriales	201174|Actinobacteria	L	tyrosine recombinase	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_1645590_11	1123248.KB893370_gene5151	1.126e-05	49.0	COG3386@1|root,COG5295@1|root,COG3386@2|Bacteria,COG5295@2|Bacteria,4NMCF@976|Bacteroidetes,1IWGC@117747|Sphingobacteriia	2|Bacteria	UW	Domain of unknown function (DUF5122) beta-propeller	yeeJ	-	-	ko:K14274,ko:K20276,ko:K21449	ko00040,ko02024,map00040,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
SRR25158416_k127_1645590_9	265072.Mfla_1537	3.286e-17	91.0	COG3558@1|root,COG3558@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1348)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1645590_3	1246459.KB898374_gene3976	1.175e-51	198.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158416_k127_1645590_2	1229780.BN381_50048	8.194e-59	224.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_1645590_4	1146883.BLASA_1224	4.775e-33	141.0	2CC93@1|root,32VVD@2|Bacteria,2IF79@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158416_k127_1645590_0	298653.Franean1_3414	1.335e-107	359.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR25158416_k127_1645590_5	136273.GY22_08730	1.049e-26	124.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,1W866@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158416_k127_1645590_6	103733.JNYO01000031_gene1595	4.171e-21	107.0	COG2197@1|root,COG2197@2|Bacteria,2GPTM@201174|Actinobacteria,4E5Q7@85010|Pseudonocardiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_1645590_1	1968.JOEV01000027_gene4621	1.456e-69	260.0	COG2197@1|root,COG3829@1|root,COG4585@1|root,COG2197@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR25158416_k127_1645590_7	411154.GFO_1836	2.562e-20	99.0	COG1520@1|root,COG2304@1|root,COG2911@1|root,COG3209@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
SRR25158416_k127_1645590_8	795797.C497_05867	6.068e-18	88.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158416_k127_1645590_10	1077972.ARGLB_083_00490	1.604e-07	54.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
SRR25158416_k127_16462_4	883066.HMPREF9233_01454	9.349e-27	110.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D6AF@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158416_k127_16462_1	196162.Noca_1378	8.177e-56	209.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DNMY@85009|Propionibacteriales	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158416_k127_16462_2	869210.Marky_0105	4.997e-36	158.0	COG2385@1|root,COG2385@2|Bacteria,1WJB9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	PFAM Stage II sporulation	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158416_k127_16462_5	1229780.BN381_220024	8.451e-21	100.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,3UWQG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CO	Thioredoxin-like	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158416_k127_16462_0	1313172.YM304_18530	3.171e-188	611.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CMPC@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158416_k127_16462_3	67356.KL575605_gene3918	5.434e-34	137.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria	201174|Actinobacteria	L	methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158416_k127_1647137_8	1050202.KB913024_gene3417	1.035e-28	127.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,408VB@622450|Actinopolysporales	201174|Actinobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158416_k127_1647137_5	512565.AMIS_33270	1.371e-50	190.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria,4D8X0@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158416_k127_1647137_6	1211815.CBYP010000036_gene2307	1.503e-44	170.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4EVPW@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158416_k127_1647137_4	67352.JODS01000001_gene476	5.022e-99	340.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158416_k127_1647137_3	67373.JOBF01000016_gene4823	6.962e-148	476.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_1647137_9	1296990.H845_3708	6.252e-08	58.0	COG3620@1|root,COG3620@2|Bacteria,1MYVA@1224|Proteobacteria,2UI2K@28211|Alphaproteobacteria,2JYUZ@204441|Rhodospirillales	204441|Rhodospirillales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1647137_7	469383.Cwoe_2650	1.871e-31	128.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1647137_1	485913.Krac_2128	2.852e-192	610.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158416_k127_1647137_0	1123319.AUBE01000010_gene4213	1.554e-232	743.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158416_k127_1647137_2	485913.Krac_2149	2.825e-150	488.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2G872@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158416_k127_1650378_3	562970.Btus_1452	2.695e-31	124.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,27A1C@186823|Alicyclobacillaceae	91061|Bacilli	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158416_k127_1650378_2	665959.HMPREF1013_02135	2.01e-42	177.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158416_k127_1650378_1	525909.Afer_1503	8.887e-45	174.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CMY6@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54
SRR25158416_k127_1650378_0	1033730.CAHG01000013_gene1327	2.626e-68	236.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DN2T@85009|Propionibacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158416_k127_165123_2	479432.Sros_9178	1.843e-39	152.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4EH9B@85012|Streptosporangiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158416_k127_165123_1	397278.JOJN01000002_gene411	2.309e-50	194.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4DQ41@85009|Propionibacteriales	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158416_k127_165123_0	1121423.JONT01000010_gene1742	9.716e-62	230.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158416_k127_165123_3	266117.Rxyl_1016	1.837e-35	151.0	COG0477@1|root,COG2814@2|Bacteria,2ID9K@201174|Actinobacteria,4CQJG@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_166830_0	671143.DAMO_1249	1.136e-200	652.0	COG1615@1|root,COG1615@2|Bacteria,2NQSF@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158416_k127_168689_8	1146883.BLASA_2363	6.98e-15	75.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4ERGS@85013|Frankiales	201174|Actinobacteria	F	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158416_k127_168689_2	351607.Acel_1297	5.769e-84	290.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4ESI4@85013|Frankiales	201174|Actinobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158416_k127_168689_1	1121430.JMLG01000006_gene1759	4.416e-92	316.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158416_k127_168689_3	1121861.KB899921_gene3002	2.187e-53	195.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,2JRPW@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158416_k127_168689_5	273068.TTE1529	1.731e-44	175.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,42FJS@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158416_k127_168689_6	675635.Psed_3521	3.521e-32	129.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4E4HM@85010|Pseudonocardiales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_168689_4	926567.TheveDRAFT_1006	1.198e-51	189.0	COG0194@1|root,COG0194@2|Bacteria,3TB1Q@508458|Synergistetes	508458|Synergistetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158416_k127_168689_7	469371.Tbis_1361	8.626e-20	93.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4E5KY@85010|Pseudonocardiales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158416_k127_168689_0	644966.Tmar_0916	1.119e-109	369.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WCE8@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158416_k127_1689617_0	1297617.JPJD01000001_gene2679	4.379e-28	120.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,268PT@186813|unclassified Clostridiales	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_1689617_1	103733.JNYO01000041_gene3960	2.968e-05	57.0	COG5660@1|root,COG5660@2|Bacteria,2IHDZ@201174|Actinobacteria,4E4SE@85010|Pseudonocardiales	201174|Actinobacteria	S	integral membrane protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_1719381_0	1380390.JIAT01000016_gene5527	2.19e-38	155.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1747375_17	465541.ATCJ01000005_gene4102	1.27e-05	51.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158416_k127_1747375_6	105420.BBPO01000033_gene3779	3.003e-84	284.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,2NE8F@228398|Streptacidiphilus	201174|Actinobacteria	L	RecR protein	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158416_k127_1747375_1	1121877.JQKF01000011_gene381	1.369e-137	451.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CMX1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158416_k127_1747375_19	658086.HMPREF0994_06590	0.0006036	50.0	2DR5I@1|root,33A9E@2|Bacteria,1VM5P@1239|Firmicutes,24UWH@186801|Clostridia,27QCK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-ribbon_3,zinc_ribbon_2
SRR25158416_k127_1747375_18	1172181.KB911722_gene5402	0.0005285	46.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,2GKJT@201174|Actinobacteria	201174|Actinobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
SRR25158416_k127_1747375_3	1173020.Cha6605_4473	3.503e-93	317.0	COG0136@1|root,COG0136@2|Bacteria,1G0E6@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158416_k127_1747375_14	367299.JOEE01000002_gene2532	5.968e-25	116.0	COG1694@1|root,COG1694@2|Bacteria,2ISAF@201174|Actinobacteria,4FJCG@85021|Intrasporangiaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158416_k127_1747375_8	570952.ATVH01000014_gene2068	1.122e-79	276.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_1747375_12	479435.Kfla_5795	7.781e-37	154.0	COG0346@1|root,COG0346@2|Bacteria,2ISP0@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158416_k127_1747375_16	1229780.BN381_220038	1.314e-12	77.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
SRR25158416_k127_1747375_7	103733.JNYO01000002_gene379	2.451e-81	287.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DXXN@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_1747375_9	1236902.ANAS01000030_gene2978	6.703e-57	210.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4EFSI@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_1747375_13	1144319.PMI16_00817	5.932e-28	118.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,4746T@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158416_k127_1747375_2	351607.Acel_2004	1.871e-127	438.0	COG0744@1|root,COG2815@1|root,COG0744@2|Bacteria,COG2815@2|Bacteria,2GK21@201174|Actinobacteria,4ERGQ@85013|Frankiales	201174|Actinobacteria	M	PFAM glycosyl transferase, family 51	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158416_k127_1747375_5	1379698.RBG1_1C00001G1760	8.852e-90	312.0	COG1030@1|root,COG1030@2|Bacteria,2NNMU@2323|unclassified Bacteria	2|Bacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
SRR25158416_k127_1747375_4	1123319.AUBE01000031_gene5073	9.555e-93	322.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158416_k127_1747375_0	1380390.JIAT01000010_gene3951	1.394e-139	455.0	COG3287@1|root,COG3287@2|Bacteria,2GTCE@201174|Actinobacteria	201174|Actinobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158416_k127_1747375_10	1121946.AUAX01000012_gene6517	9.787e-56	221.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DC8Z@85008|Micromonosporales	201174|Actinobacteria	T	Signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
SRR25158416_k127_1747375_15	1444309.JAQG01000036_gene4809	1.983e-19	96.0	COG2345@1|root,COG2345@2|Bacteria,1UYQM@1239|Firmicutes,4HFSS@91061|Bacilli,271FR@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase,HTH_20
SRR25158416_k127_1750343_8	518766.Rmar_2259	3.595e-51	193.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1FJ4Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158416_k127_1750343_2	234267.Acid_0914	1.008e-109	374.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158416_k127_1750343_1	671143.DAMO_0747	1.434e-122	404.0	COG0022@1|root,COG0022@2|Bacteria,2NNT2@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158416_k127_1750343_4	671143.DAMO_0748	5.454e-89	306.0	COG1071@1|root,COG1071@2|Bacteria,2NPBB@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158416_k127_1750343_0	58123.JOFJ01000001_gene3200	1.541e-156	506.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4EH93@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_1750343_3	222534.KB893711_gene4970	8.573e-104	350.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4ES11@85013|Frankiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158416_k127_1750343_7	42256.RradSPS_0445	2.568e-61	224.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158416_k127_1750343_5	643648.Slip_1459	2.542e-79	276.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,42JXY@68298|Syntrophomonadaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158416_k127_1750343_6	304371.MCP_1094	2.336e-76	270.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,2NA71@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158416_k127_181224_0	335543.Sfum_3994	1.964e-06	60.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MRX0@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_181224_1	1187851.A33M_2855	4.802e-05	47.0	COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,2TTX7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158416_k127_182913_8	1158150.KB906241_gene1352	3.811e-08	61.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales	135613|Chromatiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158416_k127_182913_2	55952.BU52_13695	9.898e-88	304.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_182913_0	1283283.ATXA01000001_gene777	4.952e-115	385.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4ERXN@85013|Frankiales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158416_k127_182913_6	266117.Rxyl_1440	1.491e-42	170.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CQCH@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158416_k127_182913_3	525904.Tter_0689	1.121e-62	227.0	COG1187@1|root,COG1187@2|Bacteria,2NPCM@2323|unclassified Bacteria	2|Bacteria	J	RNA pseudouridylate synthase	rluE	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158416_k127_182913_4	1384484.AEQU_0806	2.426e-49	185.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CVF5@84998|Coriobacteriia	84998|Coriobacteriia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158416_k127_182913_5	1122622.ATWJ01000010_gene1176	1.591e-44	172.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4FEWM@85021|Intrasporangiaceae	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158416_k127_182913_7	1219035.NT2_01_06140	3.328e-42	167.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2TRIF@28211|Alphaproteobacteria,2K3J2@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158416_k127_182913_1	1121346.KB899830_gene681	3.699e-91	311.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,26QE9@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158416_k127_1841631_3	33898.JRHJ01000006_gene2013	9.295e-55	217.0	COG3103@1|root,COG3103@2|Bacteria,2I3C9@201174|Actinobacteria	201174|Actinobacteria	T	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158416_k127_1841631_4	1206737.BAGF01000040_gene2186	1.222e-53	194.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria,4G93C@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1841631_10	35754.JNYJ01000004_gene6020	6.371e-12	69.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,4DET5@85008|Micromonosporales	201174|Actinobacteria	L	cysteine	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR25158416_k127_1841631_8	509190.Cseg_0271	7.556e-22	101.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158416_k127_1841631_7	219305.MCAG_00812	4.456e-26	112.0	2C4JB@1|root,30BI1@2|Bacteria,2GSUU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1841631_5	1150864.MILUP08_41832	9.584e-35	138.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria,4DF0W@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_1841631_6	1713.JOFV01000004_gene3311	1.069e-27	122.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1841631_2	1448389.BAVQ01000002_gene2863	1.035e-90	304.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158416_k127_1841631_1	479432.Sros_4198	1.142e-111	370.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4EJ1J@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_1841631_0	196162.Noca_4966	2.073e-173	572.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158416_k127_1841631_11	1089545.KB913037_gene2688	2.526e-11	64.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4EBGH@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158416_k127_1853186_13	411471.SUBVAR_05136	4.286e-16	77.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158416_k127_1853186_4	656024.FsymDg_3711	2.885e-77	276.0	COG0642@1|root,COG2205@2|Bacteria,2IBA8@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158416_k127_1853186_3	1410665.JNKR01000004_gene1468	1.916e-80	278.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158416_k127_1853186_1	555079.Toce_2072	2.481e-125	413.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,42FEW@68295|Thermoanaerobacterales	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158416_k127_1853186_7	309807.SRU_2066	3.247e-51	193.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1FJ98@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25
SRR25158416_k127_1853186_9	28042.GU90_18490	2.647e-41	166.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4DY0G@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158416_k127_1853186_11	1194972.MVAC_06297	3.385e-19	94.0	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,239QN@1762|Mycobacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	etp	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158416_k127_1853186_6	1229780.BN381_80386	8.511e-55	200.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,3UWPM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158416_k127_1853186_0	211114.JOEF01000005_gene2171	7e-179	569.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4DZ2J@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158416_k127_1853186_2	1211815.CBYP010000041_gene2543	2.407e-83	291.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4ERX0@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158416_k127_1853186_10	561175.KB894108_gene4894	2.308e-25	119.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4EGC3@85012|Streptosporangiales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158416_k127_1853186_5	1499685.CCFJ01000033_gene49	2.233e-60	220.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,1ZBEV@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_1853186_15	649831.L083_7068	6.308e-06	52.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158416_k127_1853186_16	553204.CORAM0001_0647	9.971e-05	50.0	2BJAR@1|root,32DKN@2|Bacteria,2IT37@201174|Actinobacteria,22NH3@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1853186_8	1121272.KB903272_gene41	4.085e-51	196.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4DAVG@85008|Micromonosporales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158416_k127_1853186_12	935839.JAGJ01000002_gene747	4.776e-19	89.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4F4WN@85017|Promicromonosporaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158416_k127_1853186_14	68194.JNXR01000028_gene2147	8.587e-12	68.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158416_k127_1876270_1	58123.JOFJ01000004_gene1734	2.603e-56	205.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4EHS3@85012|Streptosporangiales	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158416_k127_1876270_0	1122237.AUGQ01000006_gene23	1.101e-60	216.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4FK9B@85023|Microbacteriaceae	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158416_k127_188538_11	795359.TOPB45_0396	1.717e-35	138.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	metF3	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158416_k127_188538_6	1485544.JQKP01000013_gene1787	1.191e-97	328.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,44V2A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158416_k127_188538_3	326427.Cagg_0335	4.362e-112	367.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
SRR25158416_k127_188538_8	1408424.JHYI01000003_gene3961	9.191e-82	293.0	COG0765@1|root,COG0765@2|Bacteria,1TRX4@1239|Firmicutes,4HEAH@91061|Bacilli,1ZQ16@1386|Bacillus	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158416_k127_188538_5	1173026.Glo7428_1854	5.328e-98	334.0	COG4597@1|root,COG4597@2|Bacteria,1FZWE@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	bgtB	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158416_k127_188538_7	1173029.JH980292_gene2013	7.696e-92	316.0	COG0834@1|root,COG0834@2|Bacteria,1G0K4@1117|Cyanobacteria,1H88R@1150|Oscillatoriales	1117|Cyanobacteria	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SRR25158416_k127_188538_1	986075.CathTA2_0968	8.606e-150	491.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli	91061|Bacilli	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158416_k127_188538_9	867903.ThesuDRAFT_01448	7.394e-59	211.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WCM0@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
SRR25158416_k127_188538_2	1283299.AUKG01000001_gene2191	6.614e-118	386.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158416_k127_188538_4	67267.JNXT01000012_gene454	3.968e-101	343.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158416_k127_188538_10	290397.Adeh_1832	9.674e-56	200.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,2YV7A@29|Myxococcales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158416_k127_188538_0	1229780.BN381_130048	7.188e-247	781.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,3UWC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158416_k127_188538_12	979556.MTES_2415	2.284e-26	123.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4FMK5@85023|Microbacteriaceae	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158416_k127_188603_0	1386089.N865_08270	3.51e-302	941.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4FEFC@85021|Intrasporangiaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158416_k127_189377_1	502025.Hoch_1055	2.638e-37	161.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
SRR25158416_k127_189377_2	204669.Acid345_3934	3.117e-08	67.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria,2JMPX@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_189377_0	1123242.JH636434_gene4980	2.084e-84	281.0	COG0262@1|root,COG0262@2|Bacteria,2IYX1@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1939142_1	1382306.JNIM01000001_gene3478	1.155e-158	519.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
SRR25158416_k127_1939142_21	981383.AEWH01000006_gene3095	1.121e-09	63.0	2DNMR@1|root,32Y5G@2|Bacteria,1VHJG@1239|Firmicutes,4HNHI@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1939142_19	1476583.DEIPH_ctg103orf0058	7.273e-18	94.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR25158416_k127_1939142_18	285535.JOEY01000061_gene8706	2.203e-27	119.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158416_k127_1939142_5	247490.KSU1_B0628	5.288e-113	382.0	COG0260@1|root,COG0260@2|Bacteria,2IY4Q@203682|Planctomycetes	203682|Planctomycetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158416_k127_1939142_4	357808.RoseRS_2771	3.767e-120	403.0	COG1457@1|root,COG1457@2|Bacteria,2G9KC@200795|Chloroflexi,376PN@32061|Chloroflexia	32061|Chloroflexia	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
SRR25158416_k127_1939142_20	1380347.JNII01000005_gene3345	9.652e-17	91.0	COG5496@1|root,COG5496@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158416_k127_1939142_6	521098.Aaci_0815	7.415e-73	259.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158416_k127_1939142_15	84531.JMTZ01000038_gene3588	6.124e-31	128.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158416_k127_1939142_14	84531.JMTZ01000038_gene3588	1.343e-31	133.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158416_k127_1939142_12	644966.Tmar_1742	3.242e-35	144.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_1939142_16	644966.Tmar_1743	2.049e-30	128.0	COG0640@1|root,COG0640@2|Bacteria,1VAMP@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158416_k127_1939142_11	292459.STH2483	1.72e-44	169.0	COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,2528Q@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158416_k127_1939142_7	644966.Tmar_2134	3.17e-60	219.0	COG3396@1|root,COG3396@2|Bacteria,1TPWQ@1239|Firmicutes	1239|Firmicutes	Q	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158416_k127_1939142_3	869210.Marky_1366	9.872e-124	407.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158416_k127_1939142_9	562970.Btus_1236	6.48e-56	201.0	COG1309@1|root,COG1309@2|Bacteria,1UVX6@1239|Firmicutes,4I436@91061|Bacilli,279P3@186823|Alicyclobacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_1939142_0	357808.RoseRS_0265	1.784e-159	518.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_1939142_13	518766.Rmar_0303	4.698e-35	153.0	COG0477@1|root,COG2814@2|Bacteria,4PF2D@976|Bacteroidetes,1FK1C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1939142_17	1306174.JODP01000003_gene1783	4.179e-28	131.0	2DRIE@1|root,33BXS@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158416_k127_1939142_2	479432.Sros_8076	3.961e-153	507.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4EGRW@85012|Streptosporangiales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158416_k127_1939142_10	526225.Gobs_3885	8.957e-52	200.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,4ERQE@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158416_k127_1939142_8	1051632.TPY_0096	1.934e-58	212.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia	186801|Clostridia	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158416_k127_1981521_0	1283283.ATXA01000011_gene4750	0.0	1392.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4ERS7@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158416_k127_1998097_9	1120934.KB894422_gene2901	0.0009645	43.0	COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4E6Z1@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1998097_6	1380390.JIAT01000014_gene6142	9.298e-27	113.0	COG0640@1|root,COG0640@2|Bacteria,2GS7J@201174|Actinobacteria,4CT34@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_1998097_8	1150864.MILUP08_45116	3.863e-07	57.0	COG1872@1|root,COG1872@2|Bacteria,2GQSC@201174|Actinobacteria,4DFQ8@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158416_k127_1998097_4	690850.Desaf_2977	7.849e-62	221.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria,2M9ST@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158416_k127_1998097_3	1449976.KALB_6935	1.914e-91	308.0	COG1073@1|root,COG1073@2|Bacteria,2IGDR@201174|Actinobacteria,4DYZU@85010|Pseudonocardiales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158416_k127_1998097_7	929556.Solca_0457	4.677e-11	72.0	2E4RV@1|root,32ZKD@2|Bacteria,4NWUE@976|Bacteroidetes,1IU9D@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1998097_2	314278.NB231_03015	8.94e-117	411.0	2C40F@1|root,33WUG@2|Bacteria,1NWBW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1998097_1	1089546.AQUI01000002_gene2068	2.075e-119	419.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,409RH@622450|Actinopolysporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158416_k127_1998097_0	526225.Gobs_4050	1.666e-229	732.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4ERTG@85013|Frankiales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158416_k127_1998097_5	477641.MODMU_4460	5.822e-61	222.0	COG1051@1|root,COG2062@1|root,COG1051@2|Bacteria,COG2062@2|Bacteria,2I2N2@201174|Actinobacteria,4ESJ6@85013|Frankiales	201174|Actinobacteria	F	Nudix hydrolase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158416_k127_2013550_2	351607.Acel_1250	4.254e-54	199.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4ESEC@85013|Frankiales	201174|Actinobacteria	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158416_k127_2013550_5	1449976.KALB_801	7.043e-13	73.0	COG0457@1|root,COG0457@2|Bacteria,2I3MN@201174|Actinobacteria,4E4BA@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158416_k127_2013550_1	760568.Desku_1708	2.849e-56	213.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158416_k127_2013550_6	765910.MARPU_12355	4.08e-08	59.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1WY0C@135613|Chromatiales	135613|Chromatiales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158416_k127_2013550_0	479432.Sros_6066	7.733e-72	254.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4EGY5@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_2013550_4	446468.Ndas_3039	4.43e-16	87.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4EJ98@85012|Streptosporangiales	201174|Actinobacteria	J	pseudouridine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158416_k127_2013550_3	463191.SSEG_10950	2.74e-21	94.0	2EPJ6@1|root,33H5U@2|Bacteria,2IT42@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2033710_0	1121430.JMLG01000003_gene636	1.677e-55	207.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,2607W@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158416_k127_2033710_1	370438.PTH_2552	8.71e-55	199.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158416_k127_2033710_3	1068980.ARVW01000001_gene7625	4.964e-53	192.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4DXJH@85010|Pseudonocardiales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158416_k127_2033710_4	321955.AAGP01000037_gene2515	2.507e-44	173.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4F8TS@85019|Brevibacteriaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158416_k127_2033710_5	234267.Acid_0127	1.584e-35	145.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
SRR25158416_k127_2033710_2	292459.STH1920	3.887e-54	196.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158416_k127_2051855_6	525904.Tter_1697	3.129e-57	203.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
SRR25158416_k127_2051855_10	1128421.JAGA01000002_gene1803	1.085e-25	110.0	COG2146@1|root,COG2146@2|Bacteria,2NQ87@2323|unclassified Bacteria	2|Bacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158416_k127_2051855_3	1167632.AJTR01000021_gene1356	8.159e-97	323.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,4GX1G@90964|Staphylococcaceae	91061|Bacilli	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158416_k127_2051855_1	266117.Rxyl_0166	3.339e-160	516.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158416_k127_2051855_9	525367.HMPREF0556_11465	2.273e-39	151.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,26JTS@186820|Listeriaceae	91061|Bacilli	C	Nitrogen fixation protein NifU	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158416_k127_2051855_13	882086.SacxiDRAFT_1551	7.421e-06	57.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4E42K@85010|Pseudonocardiales	201174|Actinobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158416_k127_2051855_12	365528.KB891126_gene3214	4.081e-11	74.0	28HG7@1|root,32T0H@2|Bacteria,2IFQ1@201174|Actinobacteria,4EVYV@85013|Frankiales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158416_k127_2051855_4	886293.Sinac_5350	2.904e-94	326.0	COG1929@1|root,COG1929@2|Bacteria,2IZSZ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158416_k127_2051855_7	1961.JOAK01000012_gene6100	7.371e-43	163.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158416_k127_2051855_8	1504319.GM45_0695	2.137e-39	149.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,3UWKW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Iron-sulphur cluster biosynthesis	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158416_k127_2051855_5	515635.Dtur_1756	1.448e-69	247.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR25158416_k127_2051855_2	1379698.RBG1_1C00001G1220	2.458e-120	400.0	COG0620@1|root,COG0620@2|Bacteria,2NPAE@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Meth_synt_1,Meth_synt_2
SRR25158416_k127_2051855_0	469383.Cwoe_4712	7.324e-275	857.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158416_k127_2051855_11	134676.ACPL_7853	1.924e-23	106.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DC7Q@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158416_k127_2113925_1	479434.Sthe_2024	7.68e-37	145.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_2113925_0	1128421.JAGA01000002_gene1751	1.486e-160	513.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158416_k127_2113925_4	1385520.N802_11300	2.52e-18	84.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4FHQA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158416_k127_2113925_2	1120970.AUBZ01000005_gene366	5.557e-30	126.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,466WG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818	-	-	-	-	-	-	-	-	-	-	DUF1289,NUDIX
SRR25158416_k127_2113925_3	533240.CRC_01020	1.852e-29	130.0	COG1404@1|root,COG2931@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3121@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SRR25158416_k127_2136074_0	1298863.AUEP01000019_gene3529	1.04e-98	329.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DT5X@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_2136074_1	1133850.SHJG_0801	0.0007178	45.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_2151424_2	1121468.AUBR01000095_gene761	2.3e-07	55.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42F7P@68295|Thermoanaerobacterales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158416_k127_2151424_1	429009.Adeg_0661	1.432e-91	317.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158416_k127_2151424_0	1229780.BN381_90073	6.239e-126	428.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158416_k127_2159478_2	1449355.JQNR01000005_gene5761	5.822e-73	255.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class v	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158416_k127_2159478_1	1382306.JNIM01000001_gene1934	5.948e-85	302.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158416_k127_2159478_0	1382306.JNIM01000001_gene1932	1.161e-94	322.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158416_k127_2159478_3	1158338.JNLJ01000005_gene1751	9.849e-55	203.0	COG0372@1|root,COG0372@2|Bacteria,2G4GQ@200783|Aquificae	200783|Aquificae	C	Citrate synthase, C-terminal domain	-	-	4.1.3.34	ko:K15234	ko00720,ko01100,ko01120,ko01200,map00720,map01100,map01120,map01200	M00173	R00354	RC00067,RC00502	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158416_k127_2159478_4	1380393.JHVP01000012_gene2805	1.44e-16	81.0	COG1136@1|root,COG1136@2|Bacteria,2IGR1@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_2163637_15	309801.trd_0141	2.983e-22	102.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Metallophos,fn3
SRR25158416_k127_2163637_0	290402.Cbei_1197	7.516e-126	412.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,36DRW@31979|Clostridiaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158416_k127_2163637_7	1463825.JNXC01000003_gene3810	4.798e-67	243.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4DXAV@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Peptidase family M50	rip1	GO:0008150,GO:0040007	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158416_k127_2163637_1	1280390.CBQR020000022_gene480	6.652e-116	384.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158416_k127_2163637_12	1121946.AUAX01000014_gene1035	5.473e-38	163.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4DBJT@85008|Micromonosporales	201174|Actinobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158416_k127_2163637_10	351607.Acel_1539	8.86e-59	213.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4ESC9@85013|Frankiales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158416_k127_2163637_4	656024.FsymDg_3660	8.625e-92	308.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4ERFG@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158416_k127_2163637_5	935948.KE386494_gene260	1.174e-68	239.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158416_k127_2163637_3	28042.GU90_17650	2.365e-97	328.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4DZ1Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158416_k127_2163637_14	1227454.C446_09730	2.365e-30	136.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SRR25158416_k127_2163637_13	369723.Strop_1314	6.357e-31	130.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4DEE2@85008|Micromonosporales	201174|Actinobacteria	M	peptidase M23B	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158416_k127_2163637_2	351607.Acel_1546	1.631e-97	333.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4ERYG@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_2163637_9	1348338.ADILRU_0676	2.079e-64	236.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4FKW4@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_2163637_8	1521187.JPIM01000097_gene2717	4.387e-65	229.0	COG2343@1|root,COG2343@2|Bacteria,2GARM@200795|Chloroflexi,3775Q@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158416_k127_2163637_6	1121430.JMLG01000026_gene27	1.957e-68	246.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158416_k127_2163637_11	649638.Trad_2800	2.44e-41	158.0	COG0606@1|root,COG0606@2|Bacteria,1WI18@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158416_k127_2166331_0	697281.Mahau_0303	7.192e-44	171.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,42ESG@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158416_k127_2166331_1	644966.Tmar_0720	7.589e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,1VC2F@1239|Firmicutes,24JDW@186801|Clostridia	186801|Clostridia	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_2166331_2	748247.AZKH_0212	3.546e-29	134.0	COG0642@1|root,COG0784@1|root,COG3290@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158416_k127_2166331_4	1278307.KB907015_gene3540	7.753e-24	117.0	COG2114@1|root,COG2114@2|Bacteria,1P8ZU@1224|Proteobacteria,1S6BW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19
SRR25158416_k127_2166331_3	1048339.KB913029_gene4202	6.532e-28	114.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158416_k127_2209772_0	469371.Tbis_3489	9.966e-132	428.0	COG0389@1|root,COG0389@2|Bacteria,2GKHC@201174|Actinobacteria,4DZPZ@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158416_k127_2209772_1	502025.Hoch_3345	4.439e-17	86.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
SRR25158416_k127_2292351_0	298655.KI912267_gene6991	1.353e-87	303.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4ERSJ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158416_k127_2292351_6	1380390.JIAT01000009_gene974	1.71e-38	162.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_2292351_3	1267211.KI669560_gene674	5.858e-53	196.0	COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,1IWBT@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	1.3.1.25	ko:K05783	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158416_k127_2292351_5	479432.Sros_0536	3.818e-52	194.0	2EBHZ@1|root,335IE@2|Bacteria,2GNMR@201174|Actinobacteria,4EIF8@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphatase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	-	-	-	-	-	-	-	-	-	Phosphatase
SRR25158416_k127_2292351_1	443144.GM21_0222	5.635e-60	217.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158416_k127_2292351_10	994479.GL877879_gene6175	1.603e-15	80.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,4E6MN@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM DNA binding domain, excisionase family	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_2292351_7	429009.Adeg_0989	9.417e-34	142.0	COG1341@1|root,COG1341@2|Bacteria	2|Bacteria	S	polynucleotide 5'-hydroxyl-kinase activity	-	-	-	ko:K06947	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CLP1_P
SRR25158416_k127_2292351_8	1121946.AUAX01000032_gene456	9.591e-19	94.0	COG1073@1|root,COG1073@2|Bacteria,2IPZT@201174|Actinobacteria,4DFKK@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH,Hydrolase_4
SRR25158416_k127_2292351_2	269800.Tfu_0222	6.703e-59	222.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4EFY5@85012|Streptosporangiales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158416_k127_2292351_4	592015.HMPREF1705_01539	1.534e-52	196.0	COG0693@1|root,COG0693@2|Bacteria,3TB17@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158416_k127_2292351_9	429009.Adeg_2019	5.251e-17	85.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,42GI7@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158416_k127_2305404_0	219305.MCAG_01107	6.507e-22	98.0	COG0346@1|root,COG0346@2|Bacteria,2GRN1@201174|Actinobacteria,4DG9T@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_2305404_4	309801.trd_0141	5.006e-11	73.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Metallophos,fn3
SRR25158416_k127_2305404_1	1210045.ALNP01000004_gene3459	2.105e-21	101.0	COG1595@1|root,COG1595@2|Bacteria,2IC8V@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_2305404_3	1082933.MEA186_13672	1.187e-15	91.0	2BVJQ@1|root,32QXM@2|Bacteria,1RHWS@1224|Proteobacteria,2UA5T@28211|Alphaproteobacteria,43JQQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2305404_2	720554.Clocl_4052	1.004e-15	77.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3WIA5@541000|Ruminococcaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158416_k127_2314697_5	1111069.TCCBUS3UF1_21220	7.43e-14	78.0	COG1335@1|root,COG1335@2|Bacteria,1WIVK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	PFAM Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158416_k127_2314697_4	561175.KB894099_gene4995	3.985e-14	79.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4EIHS@85012|Streptosporangiales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158416_k127_2314697_0	28042.GU90_05990	1.506e-111	375.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DX7I@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_2314697_1	208444.JNYY01000006_gene7413	1.281e-61	224.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4DYR1@85010|Pseudonocardiales	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158416_k127_2314697_3	1120934.KB894451_gene2938	3.247e-28	121.0	2DP8R@1|root,32UKH@2|Bacteria,2IFBP@201174|Actinobacteria,4E378@85010|Pseudonocardiales	201174|Actinobacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2314697_2	1313172.YM304_31100	1.121e-30	134.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158416_k127_2321518_1	1121946.AUAX01000012_gene6615	1.042e-50	194.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4DCKP@85008|Micromonosporales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158416_k127_2321518_0	1120936.KB907208_gene974	3.299e-62	219.0	28M3Q@1|root,30J0W@2|Bacteria,2I883@201174|Actinobacteria,4ERBB@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2321518_2	479432.Sros_4201	5.352e-40	151.0	COG4319@1|root,COG4319@2|Bacteria,2IRHC@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158416_k127_2321518_3	351607.Acel_1794	1.13e-31	128.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4ET2T@85013|Frankiales	201174|Actinobacteria	T	low molecular weight	arsC	-	1.20.4.1,2.8.4.2	ko:K03325,ko:K03741,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	LMWPc
SRR25158416_k127_2321518_4	298654.FraEuI1c_7181	9.228e-27	114.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria,4ET55@85013|Frankiales	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR25158416_k127_2321658_11	1003195.SCAT_2421	2.235e-21	106.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_2321658_0	469371.Tbis_0223	3.555e-269	848.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4DY9J@85010|Pseudonocardiales	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158416_k127_2321658_12	1120954.ATXE01000002_gene803	5.848e-16	82.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2321658_4	479431.Namu_3757	9.244e-69	242.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4ERNZ@85013|Frankiales	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158416_k127_2321658_7	1035308.AQYY01000001_gene2905	9.908e-56	201.0	COG0569@1|root,COG0569@2|Bacteria,1V2ZF@1239|Firmicutes,24GNX@186801|Clostridia	186801|Clostridia	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158416_k127_2321658_2	1206744.BAGL01000128_gene6756	3.613e-158	526.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4FZU5@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158416_k127_2321658_9	264732.Moth_0272	8.908e-35	153.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,42G0N@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
SRR25158416_k127_2321658_10	1280949.HAD_02915	6.565e-23	105.0	COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,2TTR8@28211|Alphaproteobacteria,43XQ8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	3-methyladenine DNA glycosylase	MA20_23545	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
SRR25158416_k127_2321658_14	644966.Tmar_0739	2.137e-05	56.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
SRR25158416_k127_2321658_6	351160.RCIX2744	2.514e-61	219.0	COG0586@1|root,arCOG03117@2157|Archaea,2XY9U@28890|Euryarchaeota,2NB98@224756|Methanomicrobia	224756|Methanomicrobia	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158416_k127_2321658_13	351607.Acel_1209	1.08e-13	83.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158416_k127_2321658_1	525904.Tter_0485	2.737e-236	754.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158416_k127_2321658_3	1146883.BLASA_0568	3.117e-124	424.0	COG0125@1|root,COG0477@1|root,COG0125@2|Bacteria,COG0477@2|Bacteria,2GNTI@201174|Actinobacteria,4ES48@85013|Frankiales	201174|Actinobacteria	EFGP	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR25158416_k127_2321658_8	1123024.AUII01000014_gene4311	1.159e-44	182.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4DYB0@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III, delta	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158416_k127_2321658_5	58123.JOFJ01000028_gene2826	6.993e-64	238.0	COG0642@1|root,COG2205@2|Bacteria,2GMB9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
SRR25158416_k127_2343613_3	350054.Mflv_0844	2.17e-34	139.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,234KT@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the NUDIX hydrolase family	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_2343613_0	561175.KB894093_gene3839	6.012e-156	504.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4EHGF@85012|Streptosporangiales	201174|Actinobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158416_k127_2343613_6	595460.RRSWK_01777	2.092e-13	78.0	2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2343613_5	1121447.JONL01000005_gene1471	4.724e-14	86.0	COG2931@1|root,COG4254@1|root,COG2931@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria,2MG62@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,HemolysinCabind,VWA_2
SRR25158416_k127_2343613_2	1214101.BN159_1299	6.198e-40	169.0	COG3210@1|root,COG3210@2|Bacteria,2I4P8@201174|Actinobacteria	201174|Actinobacteria	U	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158416_k127_2343613_1	351607.Acel_0550	8.792e-120	395.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4EUA1@85013|Frankiales	201174|Actinobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158416_k127_2343613_4	304371.MCP_1088	9.667e-16	78.0	COG3729@1|root,arCOG10926@2157|Archaea	2157|Archaea	S	general stress protein B in uncultured methanogenic archaeon (Q0W564)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2343613_7	1116472.MGMO_45c00700	5.064e-10	64.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales	135618|Methylococcales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158416_k127_2349595_1	1385520.N802_08770	2.671e-116	381.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4FF36@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158416_k127_2349595_0	1435356.Y013_05225	1.29e-200	652.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4FXK7@85025|Nocardiaceae	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158416_k127_2349595_2	1448389.BAVQ01000007_gene4217	1.698e-86	299.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	Fer4,NADHdh
SRR25158416_k127_2361538_5	429009.Adeg_0401	1.706e-36	142.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,42FTZ@68295|Thermoanaerobacterales	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158416_k127_2361538_6	1449058.JQKT01000007_gene718	7.885e-35	147.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,2II8H@201174|Actinobacteria,4FKMA@85023|Microbacteriaceae	201174|Actinobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158416_k127_2361538_3	351607.Acel_0079	1.621e-72	257.0	COG4956@1|root,COG4956@2|Bacteria	2|Bacteria	S	nuclease activity	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
SRR25158416_k127_2361538_4	1121877.JQKF01000035_gene1966	5.404e-54	195.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CN2D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158416_k127_2361538_2	1125863.JAFN01000001_gene3161	1.472e-83	293.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158416_k127_2361538_1	1121017.AUFG01000051_gene3567	0.0	1046.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4FES5@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent Clp protease	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158416_k127_2361538_8	1321775.HMPREF1980_00735	5.111e-09	62.0	2DRKZ@1|root,33C8D@2|Bacteria,2HM0Y@201174|Actinobacteria,4D65Y@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2361538_0	1313172.YM304_23290	0.0	1257.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CMWS@84992|Acidimicrobiia	84992|Acidimicrobiia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158416_k127_2361538_9	67315.JOBD01000021_gene106	0.0009606	50.0	COG0515@1|root,COG0683@1|root,COG0515@2|Bacteria,COG0683@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6,Pkinase
SRR25158416_k127_2372328_0	110319.CF8_0498	6.988e-101	347.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_6,Cytochrom_C,LVIVD,Laminin_G_3,NPCBM,PA,PKD,RicinB_lectin_2,Ricin_B_lectin
SRR25158416_k127_2372328_2	379066.GAU_2705	2.514e-09	68.0	COG0697@1|root,COG0697@2|Bacteria,1ZTRH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_2372328_1	398525.KB900701_gene1018	8.144e-22	98.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,3JST2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	MA20_19360	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158416_k127_2374136_13	1463820.JOGW01000005_gene3442	7.259e-08	53.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_2374136_11	1242864.D187_006147	7.824e-20	95.0	COG0642@1|root,COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,43C1T@68525|delta/epsilon subdivisions,2X7CE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158416_k127_2374136_5	1156844.KB891820_gene144	4.952e-62	222.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158416_k127_2374136_9	1236902.ANAS01000015_gene573	2.204e-24	111.0	COG3568@1|root,COG3568@2|Bacteria,2GMRU@201174|Actinobacteria,4EJVB@85012|Streptosporangiales	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158416_k127_2374136_2	272844.PAB0593	2.349e-89	306.0	COG0549@1|root,arCOG00863@2157|Archaea,2XTCB@28890|Euryarchaeota,243F1@183968|Thermococci	183968|Thermococci	E	Belongs to the carbamate kinase family	cpkA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158416_k127_2374136_0	926550.CLDAP_16590	2.054e-170	546.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2374136_8	653045.Strvi_4628	1.346e-24	114.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2374136_3	1120950.KB892707_gene4827	5.069e-86	296.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4DNXD@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158416_k127_2374136_6	479434.Sthe_1024	1.752e-56	212.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi,27XGI@189775|Thermomicrobia	189775|Thermomicrobia	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2
SRR25158416_k127_2374136_1	42256.RradSPS_1289	2.848e-116	392.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4CPDY@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158416_k127_2374136_4	665577.JH993790_gene3715	6.082e-68	249.0	COG2129@1|root,COG2129@2|Bacteria,2GMTQ@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_2374136_14	1068980.ARVW01000001_gene7181	7.716e-06	56.0	COG0515@1|root,COG0515@2|Bacteria	1068980.ARVW01000001_gene7181|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2374136_7	926550.CLDAP_37610	1.745e-36	151.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158416_k127_2374136_10	1394178.AWOO02000033_gene8489	1.334e-21	106.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4EH49@85012|Streptosporangiales	201174|Actinobacteria	S	Glycine cleavage T-protein C-terminal barrel domain	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158416_k127_2374136_12	1713.JOFV01000016_gene38	5.251e-11	74.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4F1CN@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
SRR25158416_k127_2395673_1	351607.Acel_0268	1.657e-71	242.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4ERM4@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158416_k127_2395673_4	33876.JNXY01000005_gene8672	1.987e-42	167.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4D9YC@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158416_k127_2395673_0	28042.GU90_05710	1.133e-176	563.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DZ6H@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158416_k127_2395673_3	656024.FsymDg_4003	1.681e-53	196.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4ESCP@85013|Frankiales	201174|Actinobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158416_k127_2395673_2	491916.RHECIAT_CH0003637	1.153e-65	235.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2U2JT@28211|Alphaproteobacteria,4BB5D@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF2	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158416_k127_2399583_2	1068978.AMETH_4900	1.026e-77	266.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4DZCI@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_2399583_3	1207076.ALAT01000011_gene1549	2.728e-21	107.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1Z0VX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
SRR25158416_k127_2399583_0	1298863.AUEP01000002_gene1491	1.76e-125	414.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DPJ3@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158416_k127_2399583_1	215803.DB30_4745	9.943e-89	306.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158416_k127_2399583_4	1120950.KB892707_gene4863	1.68e-14	76.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4DNAK@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158416_k127_2407793_0	251221.35212930	1.703e-161	516.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_2407793_7	67356.KL575601_gene7935	3.781e-05	51.0	COG1366@1|root,COG1366@2|Bacteria,2GQAG@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158416_k127_2407793_5	1122915.AUGY01000044_gene7520	3.396e-11	70.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,26Z8T@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase-like ATPase domain	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158416_k127_2407793_3	1210046.B277_13689	1.27e-36	157.0	COG2385@1|root,COG2385@2|Bacteria,2IEPH@201174|Actinobacteria	201174|Actinobacteria	D	SpoIID LytB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LGFP,SpoIID
SRR25158416_k127_2407793_4	330214.NIDE2258	2.345e-17	85.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_2407793_1	1254432.SCE1572_41035	1.709e-57	214.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2WPIY@28221|Deltaproteobacteria,2Z0N9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158416_k127_2407793_2	215803.DB30_1747	1.766e-48	192.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_2407793_6	1247963.JPHU01000001_gene1878	7.015e-06	52.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_2452504_4	1121931.AUHG01000011_gene1622	0.0004873	46.0	COG4932@1|root,COG4932@2|Bacteria,4NK3C@976|Bacteroidetes,1I0WF@117743|Flavobacteriia	976|Bacteroidetes	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2452504_2	408672.NBCG_05370	3.014e-31	128.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR25158416_k127_2452504_3	653045.Strvi_4912	9.259e-05	53.0	COG0477@1|root,COG0477@2|Bacteria,2GMFC@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158416_k127_2452504_0	945713.IALB_1286	2.486e-127	417.0	COG2170@1|root,COG2170@2|Bacteria	2|Bacteria	S	glutamate-cysteine ligase activity	ybdK	GO:0003674,GO:0003824,GO:0016874,GO:0016879	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158416_k127_2452504_1	656024.FsymDg_2376	6.508e-97	331.0	COG0815@1|root,COG1215@1|root,COG0815@2|Bacteria,COG1215@2|Bacteria,2GJ9F@201174|Actinobacteria,4ERH9@85013|Frankiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158416_k127_2474297_8	101510.RHA1_ro01178	1.382e-07	55.0	2AR1Y@1|root,31GAW@2|Bacteria,2HK0E@201174|Actinobacteria,4G7PU@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2474297_4	68219.JNXI01000040_gene5464	3.995e-27	117.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158416_k127_2474297_5	1206741.BAFX01000084_gene6270	8.303e-19	102.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2474297_7	324057.Pjdr2_3063	1.022e-07	65.0	COG4409@1|root,COG4409@2|Bacteria,1VTIQ@1239|Firmicutes,4HUHA@91061|Bacilli,26TV7@186822|Paenibacillaceae	91061|Bacilli	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2474297_2	1111479.AXAR01000003_gene1711	7.011e-106	363.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli,2785A@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158416_k127_2474297_0	1120973.AQXL01000131_gene2036	7.023e-135	438.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,2788A@186823|Alicyclobacillaceae	91061|Bacilli	C	Transketolase, pyrimidine binding domain	dxpS	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158416_k127_2474297_1	1118054.CAGW01000080_gene2776	3.344e-122	401.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,26TZ7@186822|Paenibacillaceae	91061|Bacilli	C	Dehydrogenase E1 component	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
SRR25158416_k127_2474297_3	1121952.ATXT01000018_gene1917	2.268e-32	139.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FM3W@85023|Microbacteriaceae	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_2477750_7	118166.JH976537_gene205	2.1e-10	64.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHSY@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
SRR25158416_k127_2477750_6	525909.Afer_1810	7.501e-31	122.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158416_k127_2477750_0	1288083.AUKR01000002_gene4563	2.789e-158	514.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158416_k127_2477750_4	390874.Tpet_0617	3.467e-71	259.0	COG0176@1|root,COG0176@2|Bacteria,2GC05@200918|Thermotogae	200918|Thermotogae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0295	TAL_FSA
SRR25158416_k127_2477750_5	670487.Ocepr_1323	7.586e-61	224.0	COG2074@1|root,COG2074@2|Bacteria,1WI2U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	2-phosphoglycerate kinase	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	AAA_33,ATP-cone
SRR25158416_k127_2477750_1	266117.Rxyl_1657	7.233e-113	386.0	COG2403@1|root,COG2403@2|Bacteria,2H3G5@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	-
SRR25158416_k127_2477750_2	266117.Rxyl_1658	9.404e-92	308.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_2477750_3	525909.Afer_1990	1.268e-74	265.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CNDB@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158416_k127_2506753_28	1121430.JMLG01000031_gene1629	6.825e-26	111.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,2626H@186807|Peptococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158416_k127_2506753_0	1504319.GM45_5175	2.4e-252	799.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,3UWB9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158416_k127_2506753_13	309801.trd_0273	4.929e-70	268.0	COG0577@1|root,COG0577@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158416_k127_2506753_8	309801.trd_0272	9.665e-81	275.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_2506753_14	58123.JOFJ01000017_gene4162	8.185e-70	240.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4EIYA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158416_k127_2506753_11	1123320.KB889665_gene1389	5.596e-76	269.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158416_k127_2506753_10	525909.Afer_0945	2.857e-77	285.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CMXX@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
SRR25158416_k127_2506753_12	246194.CHY_1513	6.362e-75	260.0	COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,42FRF@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158416_k127_2506753_30	394221.Mmar10_1900	1.051e-17	87.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Preprotein translocase subunit (YajC)	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158416_k127_2506753_21	656024.FsymDg_0784	2.05e-51	189.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4EV3P@85013|Frankiales	201174|Actinobacteria	S	TIGRFAM channel protein, hemolysin III family	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158416_k127_2506753_31	1304888.ATWF01000001_gene1479	3.594e-13	73.0	2DNS1@1|root,32YVX@2|Bacteria,2GG1X@200930|Deferribacteres	200930|Deferribacteres	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158416_k127_2506753_4	1235794.C811_00899	7.849e-133	432.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CUPG@84998|Coriobacteriia	84998|Coriobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158416_k127_2506753_25	370438.PTH_1026	8.34e-33	138.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,26290@186807|Peptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158416_k127_2506753_26	926569.ANT_13740	2.886e-29	123.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158416_k127_2506753_9	525909.Afer_1219	9.874e-80	282.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CMY7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158416_k127_2506753_17	1343740.M271_10395	7.969e-58	206.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158416_k127_2506753_5	469383.Cwoe_3749	6.968e-132	428.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CPN5@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158416_k127_2506753_24	867903.ThesuDRAFT_01258	3.285e-36	148.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,24IDC@186801|Clostridia	186801|Clostridia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_2506753_3	429009.Adeg_0007	5.526e-137	441.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,42EVS@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158416_k127_2506753_32	1077972.ARGLB_113_00660	4.874e-09	66.0	COG3631@1|root,COG3631@2|Bacteria,2IJ9D@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158416_k127_2506753_18	351607.Acel_1702	1.687e-56	211.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4ET4R@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158416_k127_2506753_6	1047013.AQSP01000139_gene2394	6.745e-90	304.0	COG0501@1|root,COG0501@2|Bacteria,2NP1V@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
SRR25158416_k127_2506753_15	273068.TTE1795	4.819e-61	216.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,42G50@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM LemA family protein	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158416_k127_2506753_20	446469.Sked_13680	8.733e-54	201.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158416_k127_2506753_23	2045.KR76_18970	7.706e-43	170.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4DPIC@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	mntB	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158416_k127_2506753_19	1043205.AFYF01000053_gene3087	4.142e-54	209.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4FFBH@85021|Intrasporangiaceae	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158416_k127_2506753_27	1122997.AUDD01000024_gene1138	3.845e-27	126.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4DQZK@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158416_k127_2506753_22	1089550.ATTH01000001_gene1856	1.854e-49	188.0	COG0124@1|root,COG0124@2|Bacteria,4PEY8@976|Bacteroidetes,1FJUN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2506753_2	1089550.ATTH01000001_gene1855	2.571e-141	462.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1FJT4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Fumarylacetoacetase N-terminal	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158416_k127_2506753_7	1205910.B005_3737	5.814e-81	285.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4EGYP@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158416_k127_2506753_16	591158.SSMG_04262	1.855e-59	224.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria	201174|Actinobacteria	M	Lipid A biosynthesis	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158416_k127_2506753_33	1122182.KB903825_gene320	0.0002654	51.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4DCRP@85008|Micromonosporales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158416_k127_2506753_1	401526.TcarDRAFT_2201	7.987e-217	694.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,4H1Y3@909932|Negativicutes	909932|Negativicutes	J	elongation factor G	fusA_1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158416_k127_2506753_29	1121372.AULK01000003_gene12	2.359e-21	95.0	COG0695@1|root,COG0695@2|Bacteria,2GQ85@201174|Actinobacteria,4FQ09@85023|Microbacteriaceae	201174|Actinobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158416_k127_2547973_0	269800.Tfu_2657	1.407e-86	299.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4EG6U@85012|Streptosporangiales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158416_k127_2547973_2	196162.Noca_0696	1.673e-58	207.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4DQC0@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158416_k127_2547973_1	1120972.AUMH01000017_gene703	2.811e-62	228.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,2781J@186823|Alicyclobacillaceae	91061|Bacilli	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158416_k127_2547973_9	1229780.BN381_350057	5.516e-07	61.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158416_k127_2547973_6	1229780.BN381_610018	9.791e-34	136.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_2547973_5	55952.BU52_15915	2.732e-34	137.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158416_k127_2547973_4	405948.SACE_6876	9.872e-39	151.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4E3JC@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the UPF0336 family	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158416_k127_2547973_3	656024.FsymDg_1444	2.097e-42	165.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EVFA@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2547973_8	479433.Caci_0897	1.918e-18	85.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158416_k127_2547973_7	656024.FsymDg_3963	4.755e-24	101.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158416_k127_2584684_9	469371.Tbis_0680	1.689e-31	127.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4E0NX@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158416_k127_2584684_5	867903.ThesuDRAFT_01560	8.805e-76	269.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WDIB@538999|Clostridiales incertae sedis	186801|Clostridia	S	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158416_k127_2584684_0	751945.Theos_0613	9.162e-143	473.0	COG3845@1|root,COG3845@2|Bacteria,1WIKU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158416_k127_2584684_4	867903.ThesuDRAFT_01562	6.224e-79	277.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3WDF7@538999|Clostridiales incertae sedis	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158416_k127_2584684_6	379066.GAU_3928	2.805e-67	234.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158416_k127_2584684_8	479433.Caci_7934	1.609e-43	166.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158416_k127_2584684_12	1313172.YM304_12650	4.866e-14	77.0	COG3255@1|root,COG3255@2|Bacteria,2HGCC@201174|Actinobacteria,4CNAG@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2584684_13	1034347.CAHJ01000081_gene1362	1.769e-13	76.0	2DGVU@1|root,2ZXGD@2|Bacteria,1W2UG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2584684_1	1122611.KB904018_gene7040	7.385e-137	443.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4EFX2@85012|Streptosporangiales	201174|Actinobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158416_k127_2584684_3	40571.JOEA01000050_gene7496	2.66e-105	365.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria,4EBUX@85010|Pseudonocardiales	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
SRR25158416_k127_2584684_11	298654.FraEuI1c_0954	1.906e-15	79.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,4ETKQ@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2584684_7	1304876.AZVC01000002_gene853	1.162e-62	222.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,1WBSU@1268|Micrococcaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158416_k127_2584684_2	1121406.JAEX01000007_gene2396	1.345e-126	437.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2M9B2@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
SRR25158416_k127_2584684_10	1349767.GJA_1425	3.139e-21	93.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,474DH@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158416_k127_2607036_2	309801.trd_1178	8.658e-72	246.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158416_k127_2607036_7	471852.Tcur_4062	1.114e-14	75.0	COG2835@1|root,COG2835@2|Bacteria,2GQPR@201174|Actinobacteria,4EKI6@85012|Streptosporangiales	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158416_k127_2607036_3	760568.Desku_3301	3.021e-69	249.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRR25158416_k127_2607036_4	326423.RBAM_021600	8.609e-63	228.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158416_k127_2607036_0	869210.Marky_0392	1.329e-183	584.0	COG0499@1|root,COG0499@2|Bacteria,1WKSY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158416_k127_2607036_6	266117.Rxyl_1623	8.852e-37	149.0	COG1040@1|root,COG1040@2|Bacteria,2HP3J@201174|Actinobacteria,4CQES@84995|Rubrobacteria	84995|Rubrobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158416_k127_2607036_8	1445613.JALM01000013_gene2015	1.662e-07	60.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4E0UI@85010|Pseudonocardiales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158416_k127_2607036_1	1123319.AUBE01000032_gene5018	6.58e-100	330.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158416_k127_2607036_5	526227.Mesil_2250	7.16e-38	157.0	COG0477@1|root,COG0477@2|Bacteria,1WNH1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_2661271_1	667014.Thein_1281	5.489e-180	575.0	COG1350@1|root,COG1350@2|Bacteria,2GHCP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_2661271_0	1463820.JOGW01000013_gene4355	6.911e-189	596.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_2661271_2	1089545.KB913037_gene2275	1.249e-125	407.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158416_k127_2661271_3	570268.ANBB01000101_gene5798	1.974e-37	152.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria,4EQGQ@85012|Streptosporangiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_2695907_0	266117.Rxyl_2824	8.736e-232	734.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA1	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158416_k127_2695907_14	298654.FraEuI1c_0431	7.682e-27	112.0	COG2261@1|root,COG2261@2|Bacteria,2GS37@201174|Actinobacteria,4ETMQ@85013|Frankiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158416_k127_2695907_15	309800.C498_12928	6.084e-20	100.0	COG1225@1|root,arCOG00310@2157|Archaea,2XXB2@28890|Euryarchaeota,23VSA@183963|Halobacteria	183963|Halobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp-1	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158416_k127_2695907_2	1122939.ATUD01000004_gene3919	5.045e-159	514.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4CPFV@84995|Rubrobacteria	84995|Rubrobacteria	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158416_k127_2695907_1	345341.KUTG_00976	1.012e-165	547.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DYN9@85010|Pseudonocardiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158416_k127_2695907_13	656024.FsymDg_0890	5.883e-35	152.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4ESC5@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158416_k127_2695907_12	926550.CLDAP_34480	7.1e-38	147.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158416_k127_2695907_6	1184607.AUCHE_08_02220	3.195e-84	295.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4F629@85018|Dermatophilaceae	201174|Actinobacteria	H	MoeA C-terminal region (domain IV)	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158416_k127_2695907_10	502025.Hoch_4729	2.787e-46	175.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158416_k127_2695907_11	278963.ATWD01000001_gene2834	1.753e-43	164.0	COG0521@1|root,COG0521@2|Bacteria,3Y504@57723|Acidobacteria,2JJI8@204432|Acidobacteriia	204432|Acidobacteriia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158416_k127_2695907_4	1089455.MOPEL_096_00660	1.132e-100	338.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4F6PP@85018|Dermatophilaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158416_k127_2695907_8	478801.Ksed_19270	1.29e-61	237.0	COG0659@1|root,COG0659@2|Bacteria,2H1V9@201174|Actinobacteria	201174|Actinobacteria	P	Molybdate transporter of MFS superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_MOT1
SRR25158416_k127_2695907_5	1380370.JIBA01000015_gene304	1.531e-93	318.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4FI2F@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
SRR25158416_k127_2695907_7	211165.AJLN01000116_gene3309	2.431e-80	278.0	COG4447@1|root,COG4447@2|Bacteria,1GAGV@1117|Cyanobacteria	1117|Cyanobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158416_k127_2716279_2	525904.Tter_0232	7.796e-19	100.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158416_k127_2716279_1	562970.Btus_2812	2.89e-123	405.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,2797I@186823|Alicyclobacillaceae	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158416_k127_2716279_0	479432.Sros_1420	5.187e-138	452.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4EGCZ@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158416_k127_2741611_6	1380393.JHVP01000003_gene1268	5.936e-52	205.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_2741611_7	1499967.BAYZ01000090_gene4936	4.35e-44	179.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158416_k127_2741611_0	1120936.KB907209_gene1553	1.761e-231	736.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4EFI8@85012|Streptosporangiales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR25158416_k127_2741611_11	1122182.KB903814_gene3569	1.933e-18	87.0	2CA4F@1|root,33DCB@2|Bacteria,2GRQ2@201174|Actinobacteria,4DG72@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2741611_9	314271.RB2654_16261	6.124e-27	125.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,DUF1905,OmdA
SRR25158416_k127_2741611_1	1246448.ANAZ01000004_gene4790	3.264e-202	641.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4EI01@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158416_k127_2741611_12	1313265.JNIE01000003_gene1114	3.375e-16	84.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT,Gamma_PGA_hydro
SRR25158416_k127_2741611_3	525909.Afer_1266	4.743e-95	319.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158416_k127_2741611_5	469371.Tbis_1176	7.02e-55	201.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DYII@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158416_k127_2741611_14	285514.JNWO01000021_gene8047	5.531e-10	64.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2741611_4	1394178.AWOO02000034_gene8332	1.373e-82	284.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4EIC0@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158416_k127_2741611_13	590998.Celf_0802	2.004e-12	72.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158416_k127_2741611_8	1321781.HMPREF1985_01133	2.453e-32	132.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4H5BU@909932|Negativicutes	909932|Negativicutes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158416_k127_2741611_2	1254432.SCE1572_36775	1.366e-141	461.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158416_k127_2741611_10	1122611.KB903948_gene6748	1.573e-26	113.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4EIYX@85012|Streptosporangiales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158416_k127_2741611_15	1437605.BACT_0649	1.026e-08	57.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CZJH@85004|Bifidobacteriales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158416_k127_2763569_3	1160137.KB907307_gene2552	5.064e-24	111.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FW39@85025|Nocardiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158416_k127_2763569_2	1449353.JQMQ01000004_gene6328	4.995e-47	181.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,2NHIU@228398|Streptacidiphilus	201174|Actinobacteria	G	ATP-NAD kinase	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_CG,NAD_kinase
SRR25158416_k127_2763569_0	1078020.KEK_19781	7.979e-75	263.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,2347J@1762|Mycobacteriaceae	201174|Actinobacteria	J	Hemolysin TlyA	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158416_k127_2763569_4	543632.JOJL01000032_gene6308	0.0001254	50.0	COG3937@1|root,COG3937@2|Bacteria,2ISFA@201174|Actinobacteria,4DEZR@85008|Micromonosporales	201174|Actinobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR25158416_k127_2763569_1	118163.Ple7327_1486	5.372e-64	230.0	COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria,3VHW6@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158416_k127_2789670_5	908337.HMPREF9257_0176	6.169e-19	96.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,27DDB@186827|Aerococcaceae	91061|Bacilli	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158416_k127_2789670_0	55952.BU52_27140	2.291e-123	406.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158416_k127_2789670_4	1089544.KB912942_gene2807	6.87e-34	139.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria,4E5TR@85010|Pseudonocardiales	201174|Actinobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR
SRR25158416_k127_2789670_3	869210.Marky_1071	1.848e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,1WKHQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_2789670_6	1121926.AXWO01000004_gene1015	1.555e-07	61.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4EZQ0@85014|Glycomycetales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158416_k127_2789670_1	1463861.JNXE01000002_gene6538	9.091e-110	373.0	COG1208@1|root,COG1208@2|Bacteria,2HTK4@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,NTP_transferase
SRR25158416_k127_2789670_2	1265310.CCBD010000088_gene4496	2.841e-43	169.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,232XZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2817179_14	1173264.KI913949_gene1699	3.116e-07	53.0	COG0745@1|root,COG0745@2|Bacteria,1G1DH@1117|Cyanobacteria,1H8H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K11521	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_2817179_0	996637.SGM_6204	1.14e-258	809.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158416_k127_2817179_2	1114959.SZMC14600_01292	7.187e-147	494.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4E0TN@85010|Pseudonocardiales	201174|Actinobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158416_k127_2817179_12	33876.JNXY01000010_gene2625	1.72e-12	68.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria,4DFRY@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2817179_10	469616.FMAG_01241	1.757e-20	97.0	COG0745@1|root,COG0745@2|Bacteria,379NU@32066|Fusobacteria	32066|Fusobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_2817179_9	644968.DFW101_2381	7.481e-26	113.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,43ABU@68525|delta/epsilon subdivisions,2WVAV@28221|Deltaproteobacteria,2MGV7@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158416_k127_2817179_11	1211815.CBYP010000048_gene1690	4.909e-14	79.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria,4EXIX@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158416_k127_2817179_13	1254432.SCE1572_42735	7.245e-08	59.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2YVHU@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158416_k127_2817179_5	1120973.AQXL01000135_gene1404	3.97e-51	198.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,277XW@186823|Alicyclobacillaceae	91061|Bacilli	S	AI-2E family transporter	yrrI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158416_k127_2817179_7	1303518.CCALI_00427	9.38e-29	123.0	COG0745@1|root,COG0745@2|Bacteria	1303518.CCALI_00427|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
SRR25158416_k127_2817179_3	1089553.Tph_c26450	1.38e-125	414.0	COG0438@1|root,COG0438@2|Bacteria,1TS4X@1239|Firmicutes,24BYU@186801|Clostridia,42F0Q@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158416_k127_2817179_4	469371.Tbis_3303	5.288e-123	422.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4DYIK@85010|Pseudonocardiales	201174|Actinobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158416_k127_2817179_6	749414.SBI_04952	1.558e-39	157.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158416_k127_2817179_15	479433.Caci_7618	8.071e-06	55.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158416_k127_2817179_8	446468.Ndas_4210	7.244e-27	111.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4EK6A@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158416_k127_2817179_1	525904.Tter_0805	1.445e-163	526.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158416_k127_2818115_1	266117.Rxyl_0911	3.368e-29	129.0	COG0760@1|root,COG0760@2|Bacteria,2IGXV@201174|Actinobacteria,4CU3I@84995|Rubrobacteria	84995|Rubrobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	SurA_N_3
SRR25158416_k127_2818115_3	28444.JODQ01000014_gene6736	6.001e-14	80.0	2E8P5@1|root,3330B@2|Bacteria,2GRP1@201174|Actinobacteria,4EPZJ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2818115_0	1382315.JPOI01000001_gene808	2.357e-44	166.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1WFQ2@129337|Geobacillus	91061|Bacilli	S	MazG nucleotide pyrophosphohydrolase domain	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRR25158416_k127_2818531_0	880072.Desac_0095	7.719e-69	243.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
SRR25158416_k127_2818531_1	266117.Rxyl_2783	2.602e-32	134.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRR25158416_k127_2838240_6	1051632.TPY_0464	0.0001157	51.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07636,ko:K07652	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_like
SRR25158416_k127_2838240_3	1123024.AUII01000001_gene2905	4.683e-55	202.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DXC6@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2838240_4	525904.Tter_1833	4.543e-27	114.0	COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria	2|Bacteria	S	Pfam:DUF59	yitW	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158416_k127_2838240_1	68260.JOAY01000003_gene4488	8.84e-117	381.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158416_k127_2838240_5	205922.Pfl01_4312	2.014e-05	52.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria,1YQK1@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Antibiotic biosynthesis monooxygenase	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_2838240_0	525904.Tter_1698	1.229e-236	739.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158416_k127_2838240_2	42256.RradSPS_2724	4.19e-71	252.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158416_k127_2977405_14	1172188.KB911820_gene3081	3.994e-26	116.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria,4FG46@85021|Intrasporangiaceae	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158416_k127_2977405_5	298654.FraEuI1c_1130	9.417e-89	316.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158416_k127_2977405_12	1114959.SZMC14600_14165	3.421e-27	124.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4DZ4U@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158416_k127_2977405_16	477974.Daud_0838	3.408e-18	93.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158416_k127_2977405_7	1122138.AQUZ01000019_gene8173	3.552e-67	233.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_2977405_17	2074.JNYD01000024_gene2834	3.858e-18	93.0	2BTY3@1|root,32P6C@2|Bacteria,2I8RQ@201174|Actinobacteria,4ECZJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_2977405_9	483219.LILAB_06940	2.869e-36	152.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1QX6W@1224|Proteobacteria,42ZK5@68525|delta/epsilon subdivisions,2WUSH@28221|Deltaproteobacteria,2YXKX@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158416_k127_2977405_1	390989.JOEG01000008_gene1407	2.614e-186	606.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4D9AJ@85008|Micromonosporales	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158416_k127_2977405_2	555079.Toce_1227	2.298e-177	572.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42F33@68295|Thermoanaerobacterales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158416_k127_2977405_4	767817.Desgi_1868	6.029e-95	321.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,2607M@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158416_k127_2977405_8	1304865.JAGF01000001_gene3122	8.714e-53	194.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria	201174|Actinobacteria	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158416_k127_2977405_19	309800.C498_00490	2.124e-07	57.0	arCOG10157@1|root,arCOG10157@2157|Archaea,2XUTC@28890|Euryarchaeota,23TIZ@183963|Halobacteria	183963|Halobacteria	S	Ethyl tert-butyl ether degradation EthD	-	-	-	-	-	-	-	-	-	-	-	-	EthD,MmlI
SRR25158416_k127_2977405_18	408672.NBCG_00438	1.251e-09	68.0	COG3467@1|root,COG3467@2|Bacteria,2I2X2@201174|Actinobacteria,4DRZN@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_2977405_11	477641.MODMU_2470	1.43e-28	124.0	COG1113@1|root,COG1113@2|Bacteria,2GRKY@201174|Actinobacteria,4EWX2@85013|Frankiales	201174|Actinobacteria	E	amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2977405_6	37919.EP51_07120	6.893e-73	263.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4FWU0@85025|Nocardiaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2773c	DapB_C,DapB_N
SRR25158416_k127_2977405_3	561175.KB894094_gene1729	2.784e-140	457.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4EHPV@85012|Streptosporangiales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158416_k127_2977405_0	477641.MODMU_4363	6.088e-247	786.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4ERV5@85013|Frankiales	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158416_k127_2977405_10	867903.ThesuDRAFT_00228	9.66e-32	125.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WCM8@538999|Clostridiales incertae sedis	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158416_k127_2977405_15	649638.Trad_0869	2.426e-21	94.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158416_k127_2983271_0	693661.Arcve_0987	2.034e-168	544.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,245RW@183980|Archaeoglobi	183980|Archaeoglobi	L	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158416_k127_2983271_2	1382306.JNIM01000001_gene1806	9.465e-17	89.0	COG1371@1|root,COG1371@2|Bacteria,2G7BQ@200795|Chloroflexi	200795|Chloroflexi	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158416_k127_2983271_1	196162.Noca_1531	2.304e-35	145.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	mdtH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06610,ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.1.27,2.A.1.2.21	-	-	MFS_1,Sugar_tr
SRR25158416_k127_2995990_10	1454010.JEOE01000004_gene179	1.477e-16	93.0	COG4733@1|root,COG5498@1|root,COG4733@2|Bacteria,COG5498@2|Bacteria,2GNW3@201174|Actinobacteria	201174|Actinobacteria	M	glycoside hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_81,fn3
SRR25158416_k127_2995990_3	235985.BBPN01000003_gene4735	1.005e-66	248.0	COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2GJ21@201174|Actinobacteria,2NGBT@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158416_k127_2995990_7	1242864.D187_005946	2.598e-22	112.0	COG1409@1|root,COG1409@2|Bacteria,1Q32X@1224|Proteobacteria,438TJ@68525|delta/epsilon subdivisions,2X4BS@28221|Deltaproteobacteria,2YXR1@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2995990_11	2055.JNXA01000005_gene603	1.78e-15	83.0	COG1547@1|root,COG1547@2|Bacteria,2IHUS@201174|Actinobacteria,4GE58@85026|Gordoniaceae	201174|Actinobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158416_k127_2995990_1	882083.SacmaDRAFT_3058	4.286e-141	470.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4DXXQ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
SRR25158416_k127_2995990_2	1120934.KB894404_gene667	7.81e-78	273.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4DXF8@85010|Pseudonocardiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158416_k127_2995990_4	292415.Tbd_0236	2.496e-60	217.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158416_k127_2995990_5	290397.Adeh_1440	1.115e-44	169.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158416_k127_2995990_8	66897.DJ64_11120	9.335e-21	102.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_2995990_6	926550.CLDAP_06310	7.368e-39	167.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,SdrD_B
SRR25158416_k127_2995990_0	479434.Sthe_3420	1.413e-234	743.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,27XZA@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_2995990_9	266117.Rxyl_2949	4.974e-18	84.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158416_k127_3007096_0	1128421.JAGA01000002_gene1375	1.387e-226	720.0	COG2217@1|root,COG2217@2|Bacteria,2NNY4@2323|unclassified Bacteria	2|Bacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copB	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158416_k127_3007096_2	479432.Sros_9134	1.257e-27	114.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4EK99@85012|Streptosporangiales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158416_k127_3007096_1	1306174.JODP01000032_gene4027	4.05e-48	183.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158416_k127_3079550_6	390989.JOEG01000019_gene5920	2.381e-62	225.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4D8WJ@85008|Micromonosporales	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158416_k127_3079550_12	446471.Xcel_3080	7.142e-33	138.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4F46D@85017|Promicromonosporaceae	201174|Actinobacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158416_k127_3079550_14	351607.Acel_0560	1.162e-31	128.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4ET35@85013|Frankiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_3079550_16	525904.Tter_2412	9.808e-27	126.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3079550_10	309801.trd_A0767	4.69e-42	162.0	COG1268@1|root,COG1268@2|Bacteria,2GBUZ@200795|Chloroflexi,27YWE@189775|Thermomicrobia	189775|Thermomicrobia	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158416_k127_3079550_2	1123371.ATXH01000032_gene460	1.742e-76	271.0	COG0177@1|root,COG0177@2|Bacteria,2GH3R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158416_k127_3079550_9	1382315.JPOI01000001_gene1592	5.212e-43	169.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,1WFRV@129337|Geobacillus	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	fadB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158416_k127_3079550_18	1150599.MPHLEI_02788	2.101e-16	92.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
SRR25158416_k127_3079550_19	1120934.KB894405_gene5382	1.196e-13	81.0	2DN4G@1|root,32VGH@2|Bacteria,2ISQR@201174|Actinobacteria,4ECH6@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3079550_17	469383.Cwoe_3635	3.192e-19	95.0	COG0681@1|root,COG0681@2|Bacteria,2HF4W@201174|Actinobacteria,4CTUY@84995|Rubrobacteria	84995|Rubrobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158416_k127_3079550_13	1122939.ATUD01000003_gene3303	8.492e-33	135.0	2DN4G@1|root,32VGH@2|Bacteria,2HRUB@201174|Actinobacteria,4CTXR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3079550_21	396014.BF93_13950	3.587e-12	68.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4FD7I@85020|Dermabacteraceae	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_3079550_3	247156.NFA_45840	4.311e-69	241.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4FVNC@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3079550_0	935840.JAEQ01000010_gene1491	2.497e-194	626.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,43GXZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158416_k127_3079550_11	1382306.JNIM01000001_gene1358	3.403e-37	152.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158416_k127_3079550_7	525368.HMPREF0591_0167	3.822e-58	214.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,2350Y@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_2256 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3079550_1	1122182.KB903813_gene2669	8.734e-95	330.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
SRR25158416_k127_3079550_5	326427.Cagg_2708	6.665e-67	242.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158416_k127_3079550_4	316274.Haur_3061	1.913e-67	240.0	COG0745@1|root,COG0745@2|Bacteria,2GAJP@200795|Chloroflexi,37683@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3079550_8	1239962.C943_03877	2.137e-44	179.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158416_k127_3079550_20	1278073.MYSTI_02803	1.81e-13	83.0	COG0412@1|root,COG1506@1|root,COG0412@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	BAAT_C,DLH,PD40,Peptidase_S9
SRR25158416_k127_3081104_4	479432.Sros_7974	8.57e-08	53.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4EFWD@85012|Streptosporangiales	201174|Actinobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158416_k127_3081104_0	469383.Cwoe_2006	1.202e-108	355.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158416_k127_3081104_2	471853.Bcav_3954	4.851e-17	89.0	2ESVG@1|root,33KDV@2|Bacteria,2IA6T@201174|Actinobacteria	201174|Actinobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158416_k127_3081104_3	1249480.B649_03930	1.068e-08	66.0	COG2304@1|root,COG2373@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1PGYM@1224|Proteobacteria,42YEY@68525|delta/epsilon subdivisions,2YRCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3081104_1	446470.Snas_0537	1.582e-48	185.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
SRR25158416_k127_3089903_2	1121430.JMLG01000005_gene727	1.757e-07	63.0	COG3119@1|root,COG3119@2|Bacteria,1TSMM@1239|Firmicutes,247YU@186801|Clostridia,260J3@186807|Peptococcaceae	186801|Clostridia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3089903_0	526225.Gobs_4131	3.139e-151	490.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4ERJ6@85013|Frankiales	201174|Actinobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158416_k127_3089903_1	68219.JNXI01000040_gene5462	2.593e-41	161.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
SRR25158416_k127_3100491_1	1210884.HG799465_gene11952	6.287e-91	309.0	COG0626@1|root,COG0626@2|Bacteria,2IYKV@203682|Planctomycetes	203682|Planctomycetes	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158416_k127_3100491_0	1121468.AUBR01000045_gene1811	1.167e-108	366.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,42EYR@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158416_k127_3100491_2	543632.JOJL01000014_gene9104	1.701e-56	224.0	COG2199@1|root,COG3706@2|Bacteria,2I412@201174|Actinobacteria,4DGU8@85008|Micromonosporales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158416_k127_3100491_4	309801.trd_1817	3.139e-34	153.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_3100491_6	309801.trd_1551	1.189e-21	102.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3100491_5	110319.CF8_2887	4.074e-33	128.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DRPI@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158416_k127_3100491_3	1155718.KB891896_gene2198	1.201e-54	197.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158416_k127_3115160_2	2074.JNYD01000020_gene2650	3.242e-06	53.0	29C55@1|root,2ZZ3Q@2|Bacteria,2HC01@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3115160_3	765420.OSCT_2568	6.689e-05	49.0	2A42D@1|root,30SM6@2|Bacteria,2GAFV@200795|Chloroflexi,375ZW@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3115160_1	653045.Strvi_3581	2.438e-103	346.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158416_k127_3115160_0	40571.JOEA01000014_gene1788	4.194e-135	452.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DYFU@85010|Pseudonocardiales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158416_k127_3122041_4	28444.JODQ01000008_gene1080	1.962e-40	161.0	COG5002@1|root,COG5002@2|Bacteria,2I3C6@201174|Actinobacteria,4EMHB@85012|Streptosporangiales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158416_k127_3122041_6	684949.ATTJ01000001_gene903	7.522e-07	57.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3122041_0	68170.KL590558_gene5388	1.037e-143	473.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158416_k127_3122041_1	68170.KL590558_gene5392	4.068e-107	359.0	COG1409@1|root,COG3103@1|root,COG1409@2|Bacteria,COG4991@2|Bacteria,2GIT1@201174|Actinobacteria,4E0S4@85010|Pseudonocardiales	201174|Actinobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158416_k127_3122041_7	1123360.thalar_00725	0.0002202	53.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158416_k127_3122041_3	235985.BBPN01000003_gene4735	2.96e-77	273.0	COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2GJ21@201174|Actinobacteria,2NGBT@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158416_k127_3122041_5	1122609.AUGT01000009_gene3300	2.529e-17	94.0	COG2931@1|root,COG2931@2|Bacteria,2HRU5@201174|Actinobacteria,4DW0Z@85009|Propionibacteriales	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158416_k127_3122041_2	497965.Cyan7822_5426	1.106e-87	304.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	F5_F8_type_C,Metallophos
SRR25158416_k127_3131941_0	246197.MXAN_2468	1.709e-20	107.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2Z01S@29|Myxococcales	28221|Deltaproteobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
SRR25158416_k127_3154419_2	1313172.YM304_10050	9.356e-09	63.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158416_k127_3154419_3	315730.BcerKBAB4_3015	1.062e-07	60.0	COG3794@1|root,COG3794@2|Bacteria,1VQGS@1239|Firmicutes,4HXFN@91061|Bacilli,1ZH4H@1386|Bacillus	91061|Bacilli	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158416_k127_3154419_1	1448860.BBJO01000030_gene347	2.459e-22	104.0	COG0316@1|root,arCOG04560@2157|Archaea,2XXWU@28890|Euryarchaeota,23W7B@183963|Halobacteria	183963|Halobacteria	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158416_k127_3154419_0	1297742.A176_05840	5.764e-49	188.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2YUCY@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
SRR25158416_k127_316616_2	1463821.JOGR01000014_gene3427	0.0009174	44.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4EZ97@85014|Glycomycetales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_316616_1	1174528.JH992898_gene2276	2.506e-76	267.0	COG1409@1|root,COG1409@2|Bacteria,1G4KM@1117|Cyanobacteria	1117|Cyanobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158416_k127_316616_0	1449976.KALB_3688	1.195e-233	752.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria,4DZPN@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SRR25158416_k127_3185674_7	1187851.A33M_1140	3.537e-06	50.0	COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,2TVH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG1226 Kef-type K transport systems	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,cNMP_binding
SRR25158416_k127_3185674_8	58123.JOFJ01000003_gene2216	7.244e-05	48.0	29VWA@1|root,30HE5@2|Bacteria,2GY2J@201174|Actinobacteria,4EKZ0@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3185674_5	471852.Tcur_0069	1.167e-40	160.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4EFW3@85012|Streptosporangiales	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158416_k127_3185674_6	561175.KB894093_gene3929	4.047e-27	117.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4EJS2@85012|Streptosporangiales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158416_k127_3185674_4	502558.EGYY_28720	2.035e-64	237.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CUGE@84998|Coriobacteriia	84998|Coriobacteriia	T	phosphatase 2C	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
SRR25158416_k127_3185674_0	1048339.KB913029_gene1721	2.147e-128	432.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4ERWV@85013|Frankiales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158416_k127_3185674_1	351607.Acel_0020	5.457e-122	407.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4ERJZ@85013|Frankiales	201174|Actinobacteria	M	PFAM penicillin-binding protein transpeptidase	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158416_k127_3185674_3	264732.Moth_0912	2.517e-85	301.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_3185674_2	1121468.AUBR01000005_gene40	7.285e-97	334.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_3213732_14	452652.KSE_11460	4.075e-53	203.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,2M0VS@2063|Kitasatospora	201174|Actinobacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158416_k127_3213732_26	110319.CF8_2401	2.973e-11	67.0	2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4DWJ0@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
SRR25158416_k127_3213732_22	1379698.RBG1_1C00001G1271	6.039e-36	150.0	COG1630@1|root,COG1630@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR25158416_k127_3213732_4	1379698.RBG1_1C00001G1269	3.213e-142	469.0	COG0433@1|root,COG0433@2|Bacteria,2NPZD@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
SRR25158416_k127_3213732_23	1379698.RBG1_1C00001G1268	2.587e-32	143.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_3213732_13	1379698.RBG1_1C00001G1267	2.122e-54	216.0	COG0419@1|root,COG0419@2|Bacteria,2NPX7@2323|unclassified Bacteria	2|Bacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C
SRR25158416_k127_3213732_2	234267.Acid_7336	8.915e-173	557.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158416_k127_3213732_19	1207076.ALAT01000036_gene4233	2.368e-44	173.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1S1KP@1236|Gammaproteobacteria,1Z28E@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3213732_10	555088.DealDRAFT_0829	2.055e-80	289.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,42KS4@68298|Syntrophomonadaceae	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158416_k127_3213732_27	585204.SMSK597_0726	9.674e-08	63.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,2TPXE@28037|Streptococcus mitis	91061|Bacilli	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR25158416_k127_3213732_3	390989.JOEG01000001_gene5220	2.801e-167	537.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4D8NU@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158416_k127_3213732_21	1313172.YM304_16040	5.331e-38	153.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria	201174|Actinobacteria	KT	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3213732_18	1283299.AUKG01000002_gene4484	2.133e-44	170.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3213732_16	1121456.ATVA01000011_gene1415	3.764e-49	193.0	COG2972@1|root,COG4585@1|root,COG2972@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions,2WPP4@28221|Deltaproteobacteria,2MG1K@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158416_k127_3213732_8	1340434.AXVA01000003_gene2396	2.383e-104	363.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158416_k127_3213732_6	1134445.AJJM01000006_gene3304	7.405e-123	404.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_3213732_5	485913.Krac_11207	1.004e-131	435.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1e
SRR25158416_k127_3213732_7	1968.JOEV01000051_gene3583	8.608e-116	383.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158416_k127_3213732_1	1382306.JNIM01000001_gene221	2.866e-188	591.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158416_k127_3213732_20	311424.DhcVS_357	3.777e-42	167.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,34CPQ@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158416_k127_3213732_0	1120950.KB892708_gene4440	2.201e-257	820.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4DN1B@85009|Propionibacteriales	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158416_k127_3213732_11	670487.Ocepr_1417	2.402e-56	205.0	COG1647@1|root,COG1647@2|Bacteria	2|Bacteria	M	Serine aminopeptidase, S33	-	-	3.1.1.1,3.1.1.85	ko:K02170,ko:K03928	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_3213732_15	656024.FsymDg_2210	2.219e-51	191.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4ESEG@85013|Frankiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158416_k127_3213732_24	635013.TherJR_1816	5.324e-15	78.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,24V8A@186801|Clostridia	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158416_k127_3213732_25	351607.Acel_1202	4.372e-14	81.0	2BZPH@1|root,33EX8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3213732_12	477641.MODMU_2610	1.349e-55	209.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4ESDG@85013|Frankiales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158416_k127_3213732_17	469371.Tbis_1826	7.391e-48	184.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4DYXM@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158416_k127_3213732_9	760568.Desku_1909	1.285e-96	329.0	COG3502@1|root,COG3502@2|Bacteria,1TQW1@1239|Firmicutes,24952@186801|Clostridia,26116@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158416_k127_3240274_1	471852.Tcur_3294	2.443e-276	864.0	COG0468@1|root,COG1372@1|root,COG0468@2|Bacteria,COG1372@2|Bacteria,2GJ4P@201174|Actinobacteria,4EMPJ@85012|Streptosporangiales	201174|Actinobacteria	L	LAGLIDADG DNA endonuclease family	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158416_k127_3240274_13	1121365.AQXB01000001_gene874	1.526e-15	83.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,22MP4@1653|Corynebacteriaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158416_k127_3240274_11	653045.Strvi_0574	4.355e-16	88.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3240274_12	234267.Acid_0857	4.699e-16	90.0	COG3391@1|root,COG3391@2|Bacteria,3Y5TX@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158416_k127_3240274_14	1173027.Mic7113_1015	7.727e-11	70.0	COG4454@1|root,COG4454@2|Bacteria,1G83X@1117|Cyanobacteria	1117|Cyanobacteria	P	Sulfocyanin (SoxE) domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,SoxE
SRR25158416_k127_3240274_2	469371.Tbis_1120	9.501e-176	564.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria	201174|Actinobacteria	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158416_k127_3240274_4	590998.Celf_1575	4.896e-148	483.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4F0JG@85016|Cellulomonadaceae	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158416_k127_3240274_7	1120950.KB892707_gene4571	8.281e-71	257.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4DP56@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158416_k127_3240274_6	706587.Desti_3735	3.998e-81	282.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2MQD5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158416_k127_3240274_3	246194.CHY_1492	2.728e-148	479.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,42ERE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158416_k127_3240274_5	656024.FsymDg_3604	1.031e-124	421.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4ERJ5@85013|Frankiales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158416_k127_3240274_8	644966.Tmar_1083	6.598e-56	210.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WCIP@538999|Clostridiales incertae sedis	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158416_k127_3240274_15	266117.Rxyl_0857	1.135e-08	62.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158416_k127_3240274_10	1121877.JQKF01000004_gene1093	1.203e-37	153.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4CN4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158416_k127_3240274_0	269800.Tfu_2149	0.0	1127.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4EGWK@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158416_k127_3240274_9	397278.JOJN01000014_gene3559	4.968e-48	176.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4DQW7@85009|Propionibacteriales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158416_k127_3240274_16	1120945.ATUW01000005_gene623	4.698e-07	52.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3242212_0	1122138.AQUZ01000001_gene1820	0.0	1148.0	COG3696@1|root,COG3696@2|Bacteria,2H303@201174|Actinobacteria,4DWUS@85009|Propionibacteriales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158416_k127_3242212_2	1122138.AQUZ01000001_gene1819	1.603e-34	141.0	2DS99@1|root,33F32@2|Bacteria,2GXTE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3242212_1	479435.Kfla_3517	5.24e-314	972.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4DX2V@85009|Propionibacteriales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158416_k127_3243570_0	1382356.JQMP01000004_gene351	2.194e-283	896.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,27Y20@189775|Thermomicrobia	189775|Thermomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158416_k127_3243570_1	2002.JOEQ01000021_gene6733	4.715e-145	464.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4EI0M@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158416_k127_3253489_0	1380354.JIAN01000009_gene3732	7.92e-184	594.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158416_k127_3253489_3	443255.SCLAV_1880	3.043e-72	254.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	Lumazine_bd_2,NAD_binding_11,NAD_binding_2,Ribonuc_L-PSP
SRR25158416_k127_3253489_4	298654.FraEuI1c_1435	1.159e-44	175.0	2AMVA@1|root,31CS1@2|Bacteria,2IG5A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3253489_5	1380346.JNIH01000014_gene740	5.106e-29	125.0	2D9QC@1|root,32TTR@2|Bacteria,2IK1S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3253489_7	1122609.AUGT01000003_gene2423	1.942e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3253489_8	1463887.KL589970_gene4624	1.461e-10	74.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PD40
SRR25158416_k127_3253489_6	1385520.N802_06030	5.024e-26	123.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	ampC	-	3.5.2.6	ko:K01467,ko:K06160	ko01501,ko02010,ko02020,map01501,map02010,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.113.2	-	-	Beta-lactamase,DUF3471
SRR25158416_k127_3253489_1	251229.Chro_0563	1.277e-122	411.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1GR1P@1117|Cyanobacteria	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158416_k127_3253489_2	1211815.CBYP010000050_gene639	1.773e-75	263.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4ETYC@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3253550_3	1499967.BAYZ01000097_gene4346	1.447e-89	299.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9,4.3.1.9	ko:K00384,ko:K03671,ko:K22345	ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418	-	R01544,R02016,R03596,R09372	RC00013,RC00544,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913,iPC815.YPO1374	Pyr_redox_2
SRR25158416_k127_3253550_14	797114.C475_16084	3.731e-16	92.0	arCOG13010@1|root,arCOG13010@2157|Archaea,2XZYV@28890|Euryarchaeota,23XXJ@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3253550_11	986075.CathTA2_1451	4.797e-31	131.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli	91061|Bacilli	M	Peptidase, M23	lytH	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158416_k127_3253550_10	1078020.KEK_10718	2.942e-33	132.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,239Y7@1762|Mycobacteriaceae	201174|Actinobacteria	O	belongs to the thioredoxin family	trxC	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158416_k127_3253550_7	298655.KI912266_gene1159	2.175e-67	242.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4ERBQ@85013|Frankiales	201174|Actinobacteria	M	Cell wall hydrolase autolysin	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
SRR25158416_k127_3253550_6	351607.Acel_2154	2.146e-72	254.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4ERK5@85013|Frankiales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158416_k127_3253550_2	1229780.BN381_100161	1.14e-92	314.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,3UW6Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPase MipZ	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158416_k127_3253550_12	1449976.KALB_8836	9.511e-26	115.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4E30C@85010|Pseudonocardiales	201174|Actinobacteria	M	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158416_k127_3253550_9	871968.DESME_15890	2.889e-34	141.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158416_k127_3253550_8	1304874.JAFY01000007_gene2033	3.696e-35	145.0	COG0706@1|root,COG0706@2|Bacteria,3T9Q5@508458|Synergistetes	508458|Synergistetes	U	Membrane protein insertase, YidC Oxa1 family	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158416_k127_3253550_13	1321775.HMPREF1980_01528	7.009e-22	98.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4D6B8@85005|Actinomycetales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158416_k127_3253550_16	867903.ThesuDRAFT_00471	7.245e-08	59.0	COG0594@1|root,COG0594@2|Bacteria,1UE28@1239|Firmicutes,25IWC@186801|Clostridia,3WDNJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158416_k127_3253550_15	1172188.KB911820_gene2254	4.067e-11	64.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4FHTP@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158416_k127_3253550_1	1003195.SCAT_3117	8.416e-116	391.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158416_k127_3253550_4	1313172.YM304_00020	3.349e-82	286.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CN18@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase III beta subunit	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158416_k127_3253550_5	1123321.KB905820_gene5573	4.088e-73	259.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158416_k127_3253550_17	1121456.ATVA01000001_gene3127	9.347e-05	49.0	COG5512@1|root,COG5512@2|Bacteria,1NDFM@1224|Proteobacteria,42W2X@68525|delta/epsilon subdivisions,2WR7J@28221|Deltaproteobacteria,2MB4N@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158416_k127_3253550_0	266117.Rxyl_0005	9.675e-139	454.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158416_k127_3263687_2	1380347.JNII01000007_gene334	1.382e-175	567.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	-	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	Kdo,PAP2
SRR25158416_k127_3263687_3	1408473.JHXO01000011_gene3122	4.809e-132	430.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,2FND3@200643|Bacteroidia	976|Bacteroidetes	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158416_k127_3263687_4	351607.Acel_0016	4.099e-36	148.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4ESQZ@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158416_k127_3263687_1	525909.Afer_0459	2.6e-186	589.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158416_k127_3263687_0	266117.Rxyl_0816	3.781e-215	693.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CPPY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158416_k127_3263687_6	1120958.AULD01000005_gene2276	3.531e-20	94.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4FMK5@85023|Microbacteriaceae	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158416_k127_3271783_0	110319.CF8_1869	5.966e-77	273.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4DN38@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158416_k127_3272808_2	1336243.JAEA01000011_gene3217	2.479e-32	139.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,1JRHV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158416_k127_3272808_1	373903.Hore_21220	4.586e-39	155.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WBPT@53433|Halanaerobiales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158416_k127_3272808_0	1123023.JIAI01000014_gene3788	4.417e-54	196.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4E0P0@85010|Pseudonocardiales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158416_k127_3280645_8	797303.Natpe_1529	1.292e-19	100.0	COG0530@1|root,arCOG02881@2157|Archaea,2XWBG@28890|Euryarchaeota,23UDX@183963|Halobacteria	183963|Halobacteria	P	Sodium calcium exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
SRR25158416_k127_3280645_9	410359.Pcal_1143	1.984e-19	94.0	COG0517@1|root,arCOG00606@2157|Archaea,2XQQK@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_3280645_5	28042.GU90_00260	6.058e-58	208.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
SRR25158416_k127_3280645_1	869210.Marky_0500	1.935e-126	420.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158416_k127_3280645_3	479433.Caci_7822	9.144e-72	252.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria	201174|Actinobacteria	S	PHP domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158416_k127_3280645_4	1121468.AUBR01000024_gene3030	2.694e-58	226.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia,42H65@68295|Thermoanaerobacterales	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3280645_7	926560.KE387027_gene705	6.298e-36	140.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
SRR25158416_k127_3280645_6	435830.HMPREF0045_00628	7.263e-48	184.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4D4H9@85005|Actinomycetales	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158416_k127_3280645_0	1463854.JOHT01000012_gene4703	5.369e-136	440.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria	201174|Actinobacteria	G	Fructose-1,6-bisphosphatase	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158416_k127_3280645_2	1415780.JPOG01000001_gene1414	1.312e-85	304.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1X9G3@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2
SRR25158416_k127_3280645_10	390989.JOEG01000008_gene1395	7.506e-05	50.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4D9KK@85008|Micromonosporales	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158416_k127_3286448_0	1242864.D187_007752	6.798e-125	422.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158416_k127_3286448_1	858215.Thexy_1028	6.288e-102	352.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158416_k127_3286448_5	1121033.AUCF01000009_gene1079	5.313e-07	63.0	COG2931@1|root,COG2931@2|Bacteria,1NFQ5@1224|Proteobacteria,2UIZV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3286448_3	357808.RoseRS_2348	1.334e-39	167.0	COG2885@1|root,COG5492@1|root,COG2885@2|Bacteria,COG5492@2|Bacteria,2GBMA@200795|Chloroflexi,377D0@32061|Chloroflexia	32061|Chloroflexia	M	Polymorphic membrane protein, Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3286448_4	1341157.RF007C_05010	2.383e-08	67.0	COG2931@1|root,COG2931@2|Bacteria,1U2V0@1239|Firmicutes,24BFA@186801|Clostridia	186801|Clostridia	Q	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158416_k127_3286448_2	357808.RoseRS_2348	2.41e-40	169.0	COG2885@1|root,COG5492@1|root,COG2885@2|Bacteria,COG5492@2|Bacteria,2GBMA@200795|Chloroflexi,377D0@32061|Chloroflexia	32061|Chloroflexia	M	Polymorphic membrane protein, Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3288011_12	365528.KB891208_gene3063	1.453e-15	82.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4ERVJ@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158416_k127_3288011_6	349520.PPE_04915	1.494e-58	232.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,26RDT@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
SRR25158416_k127_3288011_9	222534.KB893670_gene3663	1.9e-54	203.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4ESJM@85013|Frankiales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158416_k127_3288011_14	410359.Pcal_0160	0.0002845	49.0	COG3342@1|root,arCOG04204@2157|Archaea,2XQSJ@28889|Crenarchaeota	28889|Crenarchaeota	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
SRR25158416_k127_3288011_3	1382306.JNIM01000001_gene3378	8.842e-79	273.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
SRR25158416_k127_3288011_2	1313172.YM304_09040	2.893e-119	392.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158416_k127_3288011_11	883078.HMPREF9695_02566	6.141e-16	88.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria,3JXJI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3288011_7	867845.KI911784_gene3199	7.714e-58	216.0	COG5282@1|root,COG5282@2|Bacteria,2G800@200795|Chloroflexi,3758B@32061|Chloroflexia	32061|Chloroflexia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158416_k127_3288011_13	1150864.MILUP08_40765	3.096e-09	67.0	2E6WZ@1|root,331GF@2|Bacteria,2IFC6@201174|Actinobacteria,4DDCT@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3288011_5	1380390.JIAT01000002_gene5966	4.279e-77	279.0	COG2215@1|root,COG2215@2|Bacteria,2H0S3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRR25158416_k127_3288011_4	1463936.JOJI01000049_gene5984	2.061e-78	282.0	COG0457@1|root,COG0457@2|Bacteria,2GJD3@201174|Actinobacteria	201174|Actinobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SRR25158416_k127_3288011_1	1869.MB27_06445	9.228e-152	499.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4DC84@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158416_k127_3288011_0	110319.CF8_1271	1.812e-159	516.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4DTW1@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158416_k127_3288011_10	1463909.KL585953_gene5647	2.062e-22	103.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158416_k127_3288011_8	555079.Toce_0590	2.745e-56	203.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,42FXD@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158416_k127_3294662_0	314278.NB231_09548	1.534e-138	456.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRR25158416_k127_3294662_3	266117.Rxyl_2821	1.201e-27	114.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158416_k127_3294662_2	309801.trd_1142	6.842e-115	377.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158416_k127_3294662_1	1157637.KB892092_gene6874	6.931e-123	408.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158416_k127_3296079_3	313612.L8106_12745	4.129e-05	48.0	COG0664@1|root,COG0664@2|Bacteria,1G2AJ@1117|Cyanobacteria,1HAK1@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158416_k127_3296079_1	1499967.BAYZ01000090_gene4936	2.422e-57	215.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158416_k127_3296079_0	525909.Afer_0085	2.062e-151	488.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_3296079_2	412597.AEPN01000019_gene1021	7.856e-14	83.0	COG0785@1|root,COG0785@2|Bacteria,1RBAA@1224|Proteobacteria,2U6KU@28211|Alphaproteobacteria,2PWJY@265|Paracoccus	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein	mauF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3301307_0	643648.Slip_0897	4.841e-114	373.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,42JJA@68298|Syntrophomonadaceae	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158416_k127_3301307_5	443218.AS9A_3559	3.103e-15	84.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,23AJP@1762|Mycobacteriaceae	201174|Actinobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158416_k127_3301307_4	138119.DSY3972	6.25e-35	140.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,26269@186807|Peptococcaceae	186801|Clostridia	H	PFAM 5-formyltetrahydrofolate cyclo-ligase	yqgN	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158416_k127_3301307_2	351607.Acel_0165	1.168e-96	340.0	COG2199@1|root,COG2203@1|root,COG5000@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,2IA4H@201174|Actinobacteria	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HAMP
SRR25158416_k127_3301307_1	246194.CHY_2582	3.144e-105	350.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,42EY9@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM UTP--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158416_k127_3301307_3	1155714.KB891996_gene3567	1.129e-37	148.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria	201174|Actinobacteria	H	Molybdenum cofactor synthesis domain protein	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158416_k127_330260_20	246200.SPO1094	6.613e-38	152.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,4NATB@97050|Ruegeria	28211|Alphaproteobacteria	I	Propionyl-CoA carboxylase beta	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158416_k127_330260_24	643562.Daes_1907	1.938e-29	123.0	COG1661@1|root,COG1661@2|Bacteria,1NAWT@1224|Proteobacteria,42WJ4@68525|delta/epsilon subdivisions,2WRU1@28221|Deltaproteobacteria,2MCMC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR25158416_k127_330260_21	1313172.YM304_32840	1.041e-35	148.0	COG1468@1|root,COG1468@2|Bacteria,2HE3R@201174|Actinobacteria,4CP30@84992|Acidimicrobiia	84992|Acidimicrobiia	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158416_k127_330260_10	1172181.KB911736_gene2466	8.544e-78	265.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158416_k127_330260_2	1242864.D187_005889	3.027e-194	614.0	COG0604@1|root,COG0604@2|Bacteria,1MXIK@1224|Proteobacteria,42Z30@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.3.1.85,1.3.1.86	ko:K00001,ko:K14446,ko:K17829	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	M00373	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291,R09738	RC00050,RC00076,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,AMP-binding,AMP-binding_C,CBS,ECH_1
SRR25158416_k127_330260_19	525909.Afer_0104	1.89e-38	149.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CNVV@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158416_k127_330260_3	266940.Krad_1135	9.462e-171	557.0	COG0465@1|root,COG0465@2|Bacteria,2I9X7@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158416_k127_330260_4	1048339.KB913029_gene3421	2.151e-145	471.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4ES7F@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_330260_5	1449355.JQNR01000005_gene2201	2.017e-139	456.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_330260_17	1463936.JOJI01000050_gene5835	1.34e-42	163.0	COG1607@1|root,COG1607@2|Bacteria,2GK6X@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA hydrolase	-	-	3.1.2.23	ko:K01075,ko:K10806	ko00130,ko00362,ko01040,ko01100,ko01110,ko01120,map00130,map00362,map01040,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158416_k127_330260_1	886293.Sinac_1689	1.884e-256	821.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158416_k127_330260_15	1246445.ANAY01000001_gene417	3.998e-52	207.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4EFQT@85012|Streptosporangiales	201174|Actinobacteria	K	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158416_k127_330260_16	1382356.JQMP01000004_gene340	6.258e-51	192.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,27XJM@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158416_k127_330260_13	298653.Franean1_5890	4.654e-64	229.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4ESU0@85013|Frankiales	201174|Actinobacteria	GM	Transport permease protein	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_330260_7	446466.Cfla_2372	3.452e-105	354.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158416_k127_330260_22	1235835.C814_02338	6.777e-35	150.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_2
SRR25158416_k127_330260_26	926550.CLDAP_36190	2.231e-15	87.0	COG2510@1|root,COG2510@2|Bacteria,2GBM1@200795|Chloroflexi	200795|Chloroflexi	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_330260_14	1303518.CCALI_01017	7.366e-55	207.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158416_k127_330260_11	1451189.CFAL_09015	2.883e-70	250.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,22KFH@1653|Corynebacteriaceae	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158416_k127_330260_25	656024.FsymDg_1075	3.68e-16	87.0	COG3415@1|root,COG3415@2|Bacteria,2HU0Q@201174|Actinobacteria,4EW3N@85013|Frankiales	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158416_k127_330260_6	1236902.ANAS01000034_gene1085	3.279e-119	403.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4EFGM@85012|Streptosporangiales	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158416_k127_330260_9	357808.RoseRS_1138	5.283e-84	288.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi,376XW@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM LPPG domain	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158416_k127_330260_0	65497.JODV01000006_gene847	4.792e-319	1000.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	fbiC	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158416_k127_330260_23	521393.JH806634_gene2164	4.243e-32	128.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4D6CU@85005|Actinomycetales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_330260_12	471852.Tcur_4069	4.508e-68	264.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4EHA5@85012|Streptosporangiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158416_k127_330260_18	1122939.ATUD01000004_gene3816	1.027e-41	167.0	COG1376@1|root,COG1376@2|Bacteria,2HPTN@201174|Actinobacteria,4CR7H@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158416_k127_330260_28	504474.cu0474	1.227e-10	65.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,22NKM@1653|Corynebacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
SRR25158416_k127_330260_27	56110.Oscil6304_0426	2.841e-13	74.0	2EV68@1|root,33NM1@2|Bacteria,1GFZ0@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_330260_29	1306174.JODP01000001_gene4642	3.68e-05	49.0	2DEEF@1|root,2ZMMR@2|Bacteria,2H9SH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_330260_8	1121877.JQKF01000008_gene665	9.886e-102	338.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158416_k127_333002_5	469383.Cwoe_4156	2.064e-35	136.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CP6Q@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_333002_3	246194.CHY_0655	1.608e-58	217.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,42FUD@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158416_k127_333002_4	55952.BU52_31275	1.921e-45	175.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158416_k127_333002_2	2074.JNYD01000001_gene6122	5.191e-78	268.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4DX8Q@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158416_k127_333002_0	106370.Francci3_2630	2.516e-247	777.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4ERPJ@85013|Frankiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158416_k127_333002_1	298655.KI912266_gene3656	1.443e-174	566.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4ERN8@85013|Frankiales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158416_k127_3376500_1	1304865.JAGF01000001_gene1488	1.859e-51	186.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4F1B3@85016|Cellulomonadaceae	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158416_k127_3376500_0	1380390.JIAT01000010_gene3958	5.163e-174	576.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
SRR25158416_k127_3376500_2	484770.UFO1_1101	1.302e-16	95.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
SRR25158416_k127_3391889_0	293826.Amet_0808	1.02e-109	372.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,36DHM@31979|Clostridiaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158416_k127_3391889_2	580331.Thit_0539	1.633e-33	136.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158416_k127_3391889_1	1229780.BN381_130031	4.588e-47	177.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,3UWTU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158416_k127_3394063_0	644283.Micau_1481	2.182e-79	275.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4D8XR@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158416_k127_3394063_1	1125863.JAFN01000001_gene1433	1.01e-36	145.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
SRR25158416_k127_3394997_9	926560.KE387023_gene2641	1.37e-24	118.0	COG0739@1|root,COG0739@2|Bacteria,1WK9B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158416_k127_3394997_4	1380347.JNII01000010_gene2336	3.241e-90	307.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4ESBZ@85013|Frankiales	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158416_k127_3394997_3	1313172.YM304_35550	1.925e-108	368.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CMT6@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_3394997_0	1122611.KB904001_gene8116	3.111e-156	511.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4EI1F@85012|Streptosporangiales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_3394997_1	1229780.BN381_160032	3.812e-156	514.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,3UWAP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158416_k127_3394997_8	388467.A19Y_1911	5.94e-25	118.0	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria,1HBH9@1150|Oscillatoriales	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
SRR25158416_k127_3394997_6	35754.JNYJ01000004_gene6010	8.04e-34	137.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria,4DDEB@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158416_k127_3394997_5	469371.Tbis_0320	3.097e-64	239.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,4E32N@85010|Pseudonocardiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158416_k127_3394997_10	1463881.KL591004_gene4019	1.34e-16	93.0	2DUW4@1|root,32UXY@2|Bacteria,2IJWI@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158416_k127_3394997_2	35754.JNYJ01000004_gene6013	6.669e-114	379.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria,4DB5M@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158416_k127_3394997_7	479435.Kfla_6246	4.223e-27	112.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria,4DRTG@85009|Propionibacteriales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158416_k127_3395061_3	526225.Gobs_0035	0.0005617	48.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_3395061_0	1229780.BN381_400026	6.163e-193	618.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158416_k127_3395061_1	1121430.JMLG01000007_gene2533	1.899e-174	566.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,260H6@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_3395061_2	383372.Rcas_1653	2.788e-27	124.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158416_k127_3405473_0	1382356.JQMP01000004_gene188	1.81e-108	358.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27YSW@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158416_k127_3405473_1	266117.Rxyl_0619	1.661e-107	359.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158416_k127_3405473_5	1449347.JQLN01000006_gene2685	5.724e-46	177.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,2M3DD@2063|Kitasatospora	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158416_k127_3405473_7	1304874.JAFY01000007_gene2026	8.055e-05	49.0	COG1030@1|root,COG1030@2|Bacteria,3TAG8@508458|Synergistetes	508458|Synergistetes	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
SRR25158416_k127_3405473_6	1313172.YM304_12970	4.475e-25	111.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CN6V@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158416_k127_3405473_2	1380356.JNIK01000020_gene1327	9.691e-70	263.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158416_k127_3405473_4	743719.PaelaDRAFT_0507	8.662e-50	192.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,4HE6D@91061|Bacilli,26RGF@186822|Paenibacillaceae	91061|Bacilli	M	enzyme of poly-gamma-glutamate biosynthesis (Capsule formation)	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158416_k127_3405473_3	351607.Acel_1832	2.942e-53	205.0	COG0745@1|root,COG0745@2|Bacteria,2GJRR@201174|Actinobacteria,4ESGE@85013|Frankiales	201174|Actinobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3407187_3	861299.J421_2565	2.117e-43	166.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158416_k127_3407187_2	871963.Desdi_2728	2.851e-52	201.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,260WX@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158416_k127_3407187_1	351607.Acel_1275	2.392e-95	321.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158416_k127_3407187_0	264732.Moth_0915	3.475e-104	351.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158416_k127_3407187_4	1121928.AUHE01000002_gene678	2.06e-33	134.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4GBGN@85026|Gordoniaceae	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158416_k127_3409260_0	1114856.C496_13556	5.473e-26	126.0	arCOG11394@1|root,arCOG11394@2157|Archaea,2XU8U@28890|Euryarchaeota,23UIW@183963|Halobacteria	183963|Halobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_3410831_2	671143.DAMO_2569	1.276e-24	107.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158416_k127_3410831_1	2045.KR76_10360	2.322e-43	170.0	COG1316@1|root,COG1316@2|Bacteria,2IAW9@201174|Actinobacteria,4DTHV@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158416_k127_3410831_0	1123256.KB907925_gene1069	6.363e-46	177.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1X5GT@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158416_k127_3416854_0	1128421.JAGA01000002_gene1742	2.445e-163	524.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158416_k127_3431869_1	1380347.JNII01000007_gene332	2.291e-78	274.0	COG0392@1|root,COG0392@2|Bacteria,2ICMJ@201174|Actinobacteria,4ETKK@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158416_k127_3431869_2	525904.Tter_0038	6.362e-67	235.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158416_k127_3431869_0	886293.Sinac_5883	5.897e-163	527.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158416_k127_3431869_3	562970.Btus_0232	2.927e-51	185.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,277XH@186823|Alicyclobacillaceae	91061|Bacilli	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158416_k127_3445714_3	1246484.D479_04103	2.652e-144	470.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,3NE0X@45667|Halobacillus	91061|Bacilli	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158416_k127_3445714_9	351607.Acel_0417	4.551e-53	207.0	COG3858@1|root,COG5479@1|root,COG3858@2|Bacteria,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4ESE3@85013|Frankiales	201174|Actinobacteria	M	Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme.	csp	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
SRR25158416_k127_3445714_4	479432.Sros_8404	2.427e-109	368.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4EFRE@85012|Streptosporangiales	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	mcl1	-	4.1.3.34,5.4.99.63	ko:K01644,ko:K14447	ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020	M00373	R00362,R09292	RC00067,RC01118,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158416_k127_3445714_2	656024.FsymDg_0879	1.679e-161	518.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4ERSI@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_3445714_6	42256.RradSPS_0495	5.295e-79	276.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4CRA0@84995|Rubrobacteria	84995|Rubrobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158416_k127_3445714_8	266117.Rxyl_1238	6.13e-56	209.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4CU1H@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_3445714_10	479431.Namu_3157	4.1e-49	190.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_3445714_1	4537.OPUNC05G13030.1	3.981e-170	545.0	COG1087@1|root,KOG1371@2759|Eukaryota,37K7E@33090|Viridiplantae,3GC4F@35493|Streptophyta,3KSA5@4447|Liliopsida,3I5D7@38820|Poales	35493|Streptophyta	M	GDP-mannose 4,6 dehydratase	SQD1	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006664,GO:0006950,GO:0007154,GO:0008146,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009247,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016782,GO:0019899,GO:0019904,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0101016,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158416_k127_3445714_7	298655.KI912266_gene1972	2.339e-78	269.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158416_k127_3445714_0	1382306.JNIM01000001_gene3779	2.657e-171	584.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158416_k127_3445714_5	469383.Cwoe_5791	5.458e-87	293.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158416_k127_3449601_3	1499967.BAYZ01000030_gene1167	1.535e-50	199.0	COG1520@1|root,COG1572@1|root,COG3210@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3210@2|Bacteria,2NRGG@2323|unclassified Bacteria	2|Bacteria	U	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	1.1.2.6	ko:K05889,ko:K12678	-	-	R03136	-	ko00000,ko01000,ko02000,ko02044	1.B.12.1.1,1.B.12.1.3	-	-	CARDB,Cadherin-like,Calx-beta,Chlam_PMP,Flg_new,Lectin_legB,PQQ_2,SLH
SRR25158416_k127_3449601_9	1048339.KB913029_gene2885	5.229e-15	83.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4ETJ6@85013|Frankiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_3449601_2	469371.Tbis_2039	4.672e-66	244.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4DX6V@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158416_k127_3449601_5	1223545.GS4_46_00160	2.826e-42	157.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4GDRF@85026|Gordoniaceae	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158416_k127_3449601_10	1229780.BN381_290131	4.069e-14	74.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,3UWZP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158416_k127_3449601_1	445975.COLSTE_01352	2.486e-66	230.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CUA6@84998|Coriobacteriia	84998|Coriobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158416_k127_3449601_8	1125863.JAFN01000001_gene2884	6.592e-22	103.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_3449601_7	42256.RradSPS_2707	2.371e-24	106.0	COG0662@1|root,COG0662@2|Bacteria,2IPIR@201174|Actinobacteria	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer
SRR25158416_k127_3449601_4	562970.Btus_1823	3.689e-48	193.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,279P7@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRR25158416_k127_3449601_0	635013.TherJR_1781	3.277e-157	508.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
SRR25158416_k127_3449601_6	67257.JODR01000003_gene1703	3.046e-30	121.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158416_k127_345943_2	1242864.D187_000626	1.23e-85	288.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,2YZ50@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_345943_4	1380390.JIAT01000011_gene2625	7.143e-31	141.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CQ4E@84995|Rubrobacteria	84995|Rubrobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158416_k127_345943_6	1449068.JMLQ01000002_gene3083	8.39e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4G3S0@85025|Nocardiaceae	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_345943_3	1121017.AUFG01000005_gene1040	1.286e-38	155.0	COG2032@1|root,COG2032@2|Bacteria,2GMTU@201174|Actinobacteria	201174|Actinobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005623,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0010035,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0033194,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042592,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052385,GO:0052550,GO:0052551,GO:0052564,GO:0052565,GO:0052567,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
SRR25158416_k127_345943_0	926560.KE387023_gene1619	2.125e-138	447.0	COG3227@1|root,COG3227@2|Bacteria,1WMD9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_345943_1	40571.JOEA01000050_gene7496	3.958e-134	447.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria,4EBUX@85010|Pseudonocardiales	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
SRR25158416_k127_3496258_4	1379270.AUXF01000001_gene2538	1.542e-34	134.0	COG2321@1|root,COG2321@2|Bacteria,1ZSN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158416_k127_3496258_2	469383.Cwoe_4041	7.796e-77	270.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158416_k127_3496258_6	264732.Moth_1978	0.0006108	48.0	COG5583@1|root,COG5583@2|Bacteria	2|Bacteria	S	Uncharacterized small protein (DUF2292)	yezD	-	-	-	-	-	-	-	-	-	-	-	DUF2292
SRR25158416_k127_3496258_1	443218.AS9A_3886	3.025e-81	284.0	COG0715@1|root,COG0715@2|Bacteria,2GK7X@201174|Actinobacteria,235U4@1762|Mycobacteriaceae	201174|Actinobacteria	P	NMT1-like family	ssuA3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158416_k127_3496258_0	370438.PTH_0236	1.504e-85	295.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,26175@186807|Peptococcaceae	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158416_k127_3496258_3	471852.Tcur_1033	7.646e-53	196.0	COG0600@1|root,COG0600@2|Bacteria,2GIWG@201174|Actinobacteria,4EI0V@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	ssuC3	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158416_k127_3496258_5	861299.J421_5766	2.33e-32	133.0	COG1506@1|root,COG1506@2|Bacteria,1ZUYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
SRR25158416_k127_3533981_3	589924.Ferp_0234	2.42e-59	225.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SRR25158416_k127_3533981_2	589924.Ferp_0234	7.417e-61	235.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SRR25158416_k127_3533981_0	497965.Cyan7822_5426	5.669e-101	347.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	F5_F8_type_C,Metallophos
SRR25158416_k127_3533981_4	1242864.D187_005946	5.587e-17	94.0	COG1409@1|root,COG1409@2|Bacteria,1Q32X@1224|Proteobacteria,438TJ@68525|delta/epsilon subdivisions,2X4BS@28221|Deltaproteobacteria,2YXR1@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3533981_1	497965.Cyan7822_5426	3.189e-97	334.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	F5_F8_type_C,Metallophos
SRR25158416_k127_3533981_5	1501230.ET33_16280	2.152e-16	92.0	COG3405@1|root,COG4733@1|root,COG3405@2|Bacteria,COG4733@2|Bacteria,1VT7I@1239|Firmicutes,4HV43@91061|Bacilli,27744@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_8,fn3
SRR25158416_k127_3541484_11	321327.CYA_0772	5.674e-08	59.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158416_k127_3541484_1	273068.TTE1470	3.507e-137	449.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158416_k127_3541484_9	197221.22295598	4.805e-16	82.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158416_k127_3541484_6	926567.TheveDRAFT_0986	2.018e-69	248.0	COG1028@1|root,COG1028@2|Bacteria,3TAAZ@508458|Synergistetes	508458|Synergistetes	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3541484_3	370438.PTH_1745	1.505e-95	327.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158416_k127_3541484_12	1245475.ANAE01000077_gene5214	5.329e-05	50.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,2I2S0@201174|Actinobacteria	201174|Actinobacteria	I	Biotin carboxylase	uahA	-	6.3.4.6,6.4.1.3	ko:K01941,ko:K01965	ko00220,ko00280,ko00630,ko00640,ko00791,ko01100,ko01120,ko01130,ko01200,map00220,map00280,map00630,map00640,map00791,map01100,map01120,map01130,map01200	M00373,M00741	R00774,R01859	RC00097,RC00378,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
SRR25158416_k127_3541484_7	338963.Pcar_1437	5.909e-59	217.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158416_k127_3541484_0	710111.FraQA3DRAFT_3119	5.437e-172	545.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4ES3S@85013|Frankiales	201174|Actinobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158416_k127_3541484_8	1223523.H340_24440	9.782e-47	179.0	COG1792@1|root,COG1792@2|Bacteria,2GJN0@201174|Actinobacteria	201174|Actinobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158416_k127_3541484_10	106370.Francci3_1213	4.792e-14	78.0	COG2891@1|root,COG2891@2|Bacteria,2GN0I@201174|Actinobacteria,4EWK3@85013|Frankiales	201174|Actinobacteria	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158416_k127_3541484_2	469371.Tbis_1685	4.273e-126	430.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4E550@85010|Pseudonocardiales	201174|Actinobacteria	DM	PFAM penicillin-binding protein transpeptidase	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
SRR25158416_k127_3541484_4	1120936.KB907209_gene1853	1.551e-92	321.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4EFT6@85012|Streptosporangiales	201174|Actinobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158416_k127_3541484_5	1136417.AZWE01000060_gene1625	1.863e-89	314.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4DAJS@85008|Micromonosporales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158416_k127_3549248_1	1242864.D187_005937	3.613e-56	212.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158416_k127_3549248_0	1380370.JIBA01000015_gene98	1.843e-156	525.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158416_k127_3549248_2	1500304.JQKY01000007_gene3276	4.986e-52	201.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158416_k127_3549248_3	1463900.JOIX01000041_gene1975	4.458e-37	146.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158416_k127_3549248_4	243090.RB11381	1.101e-19	101.0	2EDS4@1|root,337MM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3549248_5	1108045.GORHZ_247_00280	1.191e-12	70.0	COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,2H2SD@201174|Actinobacteria	201174|Actinobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	VRP1
SRR25158416_k127_3560982_1	345341.KUTG_06744	5.729e-80	276.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158416_k127_3560982_3	479433.Caci_1997	1.928e-08	65.0	2FFC8@1|root,3479V@2|Bacteria,2H8FE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3560982_2	1304865.JAGF01000001_gene696	1.048e-26	117.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR
SRR25158416_k127_3560982_0	405948.SACE_2888	1.591e-119	400.0	COG0076@1|root,COG0076@2|Bacteria,2I8ZZ@201174|Actinobacteria,4EA9S@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158416_k127_3565831_2	469371.Tbis_2100	6.156e-100	333.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4DYAI@85010|Pseudonocardiales	201174|Actinobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158416_k127_3565831_0	266117.Rxyl_0583	1.511e-272	846.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4CRM0@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158416_k127_3565831_4	1382359.JIAL01000001_gene2084	1.678e-87	307.0	COG0010@1|root,COG0010@2|Bacteria,3Y5KF@57723|Acidobacteria,2JNH5@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR25158416_k127_3609078_3	1382306.JNIM01000001_gene1290	8.278e-107	350.0	COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi	200795|Chloroflexi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158416_k127_3609078_1	222534.KB893748_gene2766	3.101e-115	379.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4ESBM@85013|Frankiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158416_k127_3609078_0	525904.Tter_0788	6.899e-125	409.0	COG0473@1|root,COG0473@2|Bacteria,2NP0Z@2323|unclassified Bacteria	2|Bacteria	CE	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158416_k127_3609078_2	869210.Marky_1615	4.783e-112	366.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
SRR25158416_k127_3609078_4	867903.ThesuDRAFT_00389	1.228e-65	229.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WD2K@538999|Clostridiales incertae sedis	186801|Clostridia	C	succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative mitochondrial subgroup	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158416_k127_3652197_1	1449353.JQMQ01000005_gene4782	2.627e-43	169.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,2NHWM@228398|Streptacidiphilus	201174|Actinobacteria	L	AP endonuclease family 2	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158416_k127_3652197_0	1476876.JOJO01000004_gene4735	4.655e-112	384.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_368184_1	58344.JOEL01000015_gene6355	1.467e-65	242.0	COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria	201174|Actinobacteria	O	PFAM glycosyl transferase family 39	pmt	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
SRR25158416_k127_368184_0	1123354.AUDR01000014_gene1077	1.184e-89	310.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,1KRAH@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Protein of unknown function (DUF933)	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158416_k127_368184_2	1313172.YM304_09480	5.658e-13	76.0	2ADW9@1|root,313N9@2|Bacteria,2HDCX@201174|Actinobacteria	1313172.YM304_09480|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3689406_2	1449063.JMLS01000002_gene1504	3.698e-27	123.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,26S44@186822|Paenibacillaceae	91061|Bacilli	CE	FAD dependent oxidoreductase	yhfW	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158416_k127_3689406_0	1242864.D187_001858	1.382e-174	570.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YUG7@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158416_k127_3691897_3	1172188.KB911834_gene4138	1.078e-78	270.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158416_k127_3691897_2	1169161.KB897713_gene6731	9.044e-87	291.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_3691897_4	215803.DB30_1747	4.095e-46	186.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_3691897_1	485913.Krac_1006	1.644e-105	355.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158416_k127_3691897_0	1380393.JHVP01000003_gene1268	4.435e-130	429.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_3692145_7	1484158.PSNIH1_10670	4.68e-12	70.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,1RQBF@1236|Gammaproteobacteria,3VXZA@53335|Pantoea	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iECO103_1326.ECO103_2610,iYL1228.KPN_02573	Peptidase_S11
SRR25158416_k127_3692145_4	1449976.KALB_3679	8.378e-49	187.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4DY01@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MerR family regulatory protein	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158416_k127_3692145_3	469371.Tbis_1693	6.385e-55	196.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158416_k127_3692145_5	1068980.ARVW01000001_gene7628	5.847e-46	170.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4E4H7@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158416_k127_3692145_0	1133850.SHJG_2805	7.739e-266	842.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158416_k127_3692145_6	1120959.ATXF01000008_gene461	5.581e-24	109.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4FNKM@85023|Microbacteriaceae	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158416_k127_3692145_1	1394178.AWOO02000008_gene2880	4.522e-99	326.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EH3N@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158416_k127_3692145_2	404589.Anae109_1054	1.953e-81	283.0	COG1018@1|root,COG1018@2|Bacteria,1R5FN@1224|Proteobacteria	1224|Proteobacteria	C	Oxidoreductase FAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158416_k127_3706261_2	1283299.AUKG01000001_gene2948	3.275e-22	105.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	2.2.1.2,3.1.3.3	ko:K00616,ko:K03281,ko:K07003,ko:K07182,ko:K07315,ko:K08714,ko:K10716,ko:K16922	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021	1.A.1.1,1.A.1.13,1.A.1.14,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.49	-	-	CBS,Ion_trans,NTP_transferase,cNMP_binding
SRR25158416_k127_3706261_1	365528.KB891230_gene1981	4.507e-100	362.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158416_k127_3706261_3	1480694.DC28_12460	1.162e-20	96.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K09766,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	DUF2225,HTH_Crp_2,cNMP_binding
SRR25158416_k127_3706261_4	868595.Desca_2735	4.66e-19	96.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,2633R@186807|Peptococcaceae	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158416_k127_3706261_0	525903.Taci_1006	1.666e-118	396.0	COG0172@1|root,COG0172@2|Bacteria,3T9VY@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158416_k127_3706261_5	309807.SRU_1688	1.134e-11	74.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1FJXP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158416_k127_3709946_0	351607.Acel_0758	4.425e-86	299.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4ES3D@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158416_k127_3709946_3	351607.Acel_0757	6.919e-30	121.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4ESYQ@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158416_k127_3709946_1	351607.Acel_2099	8.855e-73	262.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,2IIRA@201174|Actinobacteria,4ESMY@85013|Frankiales	201174|Actinobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,PAS,PAS_3,Response_reg
SRR25158416_k127_3709946_4	1050202.KB913024_gene2394	4.774e-19	94.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,409A7@622450|Actinopolysporales	201174|Actinobacteria	J	Ribosomal prokaryotic L21 protein	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158416_k127_3709946_2	1313172.YM304_18440	3.148e-68	236.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CMPW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribonuclease E/G family	-	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR25158416_k127_3726192_5	351607.Acel_0566	2.336e-16	79.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4ESJ1@85013|Frankiales	201174|Actinobacteria	Q	Superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158416_k127_3726192_4	879308.HMPREF9130_1755	2.378e-20	96.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,22HAS@1570339|Peptoniphilaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158416_k127_3726192_2	269800.Tfu_3101	2.386e-45	183.0	COG0477@1|root,COG2814@2|Bacteria,2I3P4@201174|Actinobacteria,4EGM4@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3726192_0	1122182.KB903815_gene1420	7.909e-164	526.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4DAG6@85008|Micromonosporales	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158416_k127_3726192_3	1169161.KB897718_gene3304	2.891e-37	147.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158416_k127_3726192_1	765910.MARPU_14455	5.098e-67	249.0	COG3379@1|root,COG3379@2|Bacteria,1PWC6@1224|Proteobacteria,1TKB0@1236|Gammaproteobacteria,1X1DI@135613|Chromatiales	135613|Chromatiales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158416_k127_3737074_6	635013.TherJR_0303	2e-66	228.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,261KH@186807|Peptococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158416_k127_3737074_19	1048834.TC41_3033	2.059e-16	82.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158416_k127_3737074_14	521098.Aaci_2702	4.527e-30	121.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,27A6H@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158416_k127_3737074_9	1194972.MVAC_07844	1.912e-60	210.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,239C5@1762|Mycobacteriaceae	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158416_k127_3737074_15	1125701.HMPREF1221_01042	4.644e-25	111.0	COG0198@1|root,COG0198@2|Bacteria,2J809@203691|Spirochaetes	203691|Spirochaetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158416_k127_3737074_4	1211815.CBYP010000046_gene908	5.1e-81	278.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4ES3Q@85013|Frankiales	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158416_k127_3737074_16	1313172.YM304_08380	1.381e-22	99.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CNZU@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158416_k127_3737074_12	65497.JODV01000007_gene460	5.029e-46	172.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4E2N4@85010|Pseudonocardiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158416_k127_3737074_8	469383.Cwoe_1355	4.669e-66	229.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158416_k127_3737074_17	1294265.JCM21738_3732	2.659e-19	97.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,1ZG7C@1386|Bacillus	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158416_k127_3737074_5	1463936.JOJI01000014_gene6932	1.447e-69	241.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158416_k127_3737074_18	35754.JNYJ01000004_gene5959	7.318e-17	83.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4DFYC@85008|Micromonosporales	201174|Actinobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158416_k127_3737074_13	309801.trd_0966	1.03e-38	151.0	COG0200@1|root,COG0200@2|Bacteria,2G6T9@200795|Chloroflexi,27YEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158416_k127_3737074_0	1449976.KALB_8203	1.753e-149	484.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4DZI2@85010|Pseudonocardiales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158416_k127_3737074_7	1123372.AUIT01000013_gene1722	3.629e-66	243.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158416_k127_3737074_2	373903.Hore_01380	2.374e-88	299.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158416_k127_3737074_20	65393.PCC7424_3724	1.066e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,1GAEI@1117|Cyanobacteria,3KIYT@43988|Cyanothece	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158416_k127_3737074_11	710111.FraQA3DRAFT_3848	3.762e-52	186.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4ESIQ@85013|Frankiales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158416_k127_3737074_10	1123320.KB889574_gene5546	3.655e-60	209.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158416_k127_3737074_3	526225.Gobs_4480	5.143e-83	280.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4EREE@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158416_k127_3737074_1	471852.Tcur_4290	1.91e-120	394.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4EGUV@85012|Streptosporangiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158416_k127_3742963_4	469383.Cwoe_1837	7.258e-104	344.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158416_k127_3742963_9	1122962.AULH01000007_gene1998	1.699e-11	72.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,36YRI@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158416_k127_3742963_5	357808.RoseRS_2408	9.833e-77	268.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158416_k127_3742963_1	469383.Cwoe_4755	8.818e-143	464.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CPS1@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_3742963_7	330084.JNYZ01000039_gene4062	2.908e-34	144.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,4DZU6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_3742963_3	211114.JOEF01000006_gene2543	1.883e-118	398.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4DZG4@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose-methanol-choline oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
SRR25158416_k127_3742963_8	1449058.JQKT01000007_gene1262	1.993e-18	90.0	COG3631@1|root,COG3631@2|Bacteria,2IIFS@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158416_k127_3742963_0	1267533.KB906735_gene4693	6.343e-145	472.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158416_k127_3742963_6	1121877.JQKF01000100_gene2	2.924e-51	199.0	2ATXZ@1|root,31JHI@2|Bacteria,2GN21@201174|Actinobacteria,4CNNN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158416_k127_3742963_2	1267534.KB906756_gene662	3.437e-135	455.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,DUF4062,NB-ARC,TPR_12,TPR_19,TPR_8,Trans_reg_C
SRR25158416_k127_3752433_1	1122929.KB908233_gene3794	2.06e-33	135.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM MazG family protein	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158416_k127_3752433_0	1449353.JQMQ01000005_gene2541	3.513e-174	555.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,2NFTP@228398|Streptacidiphilus	201174|Actinobacteria	G	Enolase, N-terminal domain	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158416_k127_3752433_4	1445613.JALM01000043_gene1630	1.182e-07	58.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4E5EA@85010|Pseudonocardiales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158416_k127_3752433_3	1123288.SOV_2c09160	1.561e-26	112.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4H4QA@909932|Negativicutes	909932|Negativicutes	J	S1 RNA binding domain protein	yugI	-	-	ko:K07571	-	-	-	-	ko00000	-	-	-	S1
SRR25158416_k127_3752433_2	285514.JNWO01000037_gene8804	5.758e-31	131.0	COG0248@1|root,COG1507@1|root,COG0248@2|Bacteria,COG1507@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158416_k127_3755046_0	1449357.JQLK01000001_gene1335	9.401e-27	121.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	mauD	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158416_k127_3755046_1	1510531.JQJJ01000015_gene3006	5.373e-15	87.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JV8J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158416_k127_3755046_2	1121946.AUAX01000005_gene5310	1.14e-12	74.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4DF8Z@85008|Micromonosporales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158416_k127_3756703_7	1136417.AZWE01000028_gene2557	5.147e-56	203.0	COG1653@1|root,COG1653@2|Bacteria,2GK9G@201174|Actinobacteria,4DAQN@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158416_k127_3756703_3	867903.ThesuDRAFT_00861	2.984e-103	357.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCSJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158416_k127_3756703_6	219305.MCAG_00845	2.96e-80	283.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4DDBX@85008|Micromonosporales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_3756703_1	1133849.O3I_033180	4.52e-119	400.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_3756703_11	1122138.AQUZ01000001_gene1687	3.422e-23	102.0	2BZ6B@1|root,30N1Q@2|Bacteria,2I097@201174|Actinobacteria,4DWBN@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3756703_2	1122138.AQUZ01000015_gene6845	2.483e-112	375.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4DVK7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158416_k127_3756703_4	926560.KE387027_gene1021	8.894e-98	337.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3756703_5	1121272.KB903256_gene5557	2.36e-84	302.0	COG3055@1|root,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4DFPE@85008|Micromonosporales	201174|Actinobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
SRR25158416_k127_3756703_9	298655.KI912267_gene7333	3.673e-33	141.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158416_k127_3756703_0	1352941.M877_09000	1.14e-143	484.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158416_k127_3756703_10	526225.Gobs_4536	5.01e-31	127.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
SRR25158416_k127_3756703_8	656024.FsymDg_0530	7.533e-48	177.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4EVK6@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3789439_4	756067.MicvaDRAFT_5451	3.006e-60	233.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
SRR25158416_k127_3789439_13	935866.JAER01000003_gene1148	6.17e-15	89.0	2DP3A@1|root,330CA@2|Bacteria,2GUX0@201174|Actinobacteria,4DT6R@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3789439_7	469383.Cwoe_5722	3.246e-29	119.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4CSVU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3789439_2	526225.Gobs_1306	4.489e-67	243.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,4ET3Y@85013|Frankiales	201174|Actinobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158416_k127_3789439_0	269800.Tfu_0559	1.825e-76	264.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4EGA9@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 3	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_3789439_11	1120949.KB903310_gene824	1.332e-19	93.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,4DDYW@85008|Micromonosporales	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158416_k127_3789439_5	1463845.JOIG01000008_gene3861	4.195e-32	129.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158416_k127_3789439_14	1274374.CBLK010000082_gene3962	2.354e-08	62.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,26XWB@186822|Paenibacillaceae	91061|Bacilli	T	Binds to sigma-B preventing the formation of an RNA polymerase holoenzyme	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158416_k127_3789439_9	1380390.JIAT01000010_gene4085	9.55e-21	96.0	2B5QA@1|root,31YJV@2|Bacteria,2HR6D@201174|Actinobacteria,4CT26@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158416_k127_3789439_15	472175.EL18_00104	6.897e-06	51.0	2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2V0ZB@28211|Alphaproteobacteria,43MEG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3096
SRR25158416_k127_3789439_12	290317.Cpha266_0880	7.444e-19	93.0	COG0745@1|root,COG0745@2|Bacteria,1FE43@1090|Chlorobi	1090|Chlorobi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3789439_6	1123288.SOV_3c03950	1.97e-29	138.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4H1VN@909932|Negativicutes	909932|Negativicutes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	AMIN,NAGPA
SRR25158416_k127_3789439_8	1163398.AJJP01000085_gene4875	2.322e-25	124.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,VWA_2
SRR25158416_k127_3789439_10	1394178.AWOO02000031_gene4790	2.468e-20	108.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TPR_6
SRR25158416_k127_3789439_1	1298863.AUEP01000005_gene2396	3.388e-71	258.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4DP1Z@85009|Propionibacteriales	201174|Actinobacteria	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158416_k127_3789439_3	479435.Kfla_3708	2.586e-63	231.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4DP39@85009|Propionibacteriales	201174|Actinobacteria	HJM	RimK-like ATP-grasp domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158416_k127_3817510_8	298653.Franean1_1404	9.565e-13	69.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR25158416_k127_3817510_16	67352.JODS01000001_gene476	6.308e-06	52.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158416_k127_3817510_17	1341646.CBMO010000147_gene4179	1.318e-05	55.0	2B81A@1|root,32195@2|Bacteria,2H57M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3817510_18	113355.CM001775_gene3305	0.0002445	46.0	2DSKU@1|root,33GJ7@2|Bacteria,1GAWU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3817510_2	222534.KB893782_gene5162	8.223e-37	162.0	COG1652@1|root,COG3629@1|root,COG1652@2|Bacteria,COG3629@2|Bacteria,2I8YV@201174|Actinobacteria	201174|Actinobacteria	NU	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
SRR25158416_k127_3817510_10	1095767.CAHD01000236_gene1897	1.778e-10	72.0	2E4WR@1|root,32ZQT@2|Bacteria,2ISS9@201174|Actinobacteria,4F2R4@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158416_k127_3817510_9	1048339.KB913029_gene217	4.39e-12	76.0	2E4ST@1|root,32ZM5@2|Bacteria,2GSCH@201174|Actinobacteria,4ETEF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158416_k127_3817510_14	653386.HMPREF0975_02851	4.506e-07	60.0	COG4961@1|root,COG4961@2|Bacteria,2GRCJ@201174|Actinobacteria,4D675@85005|Actinomycetales	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158416_k127_3817510_12	1380354.JIAN01000009_gene3757	3.532e-09	65.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158416_k127_3817510_13	1313172.YM304_01320	5.897e-08	66.0	COG2064@1|root,COG2064@2|Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_3817510_5	591159.ACEZ01000152_gene1736	7.574e-16	89.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria	201174|Actinobacteria	U	type II secretion system	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158416_k127_3817510_0	644966.Tmar_1208	2.481e-92	319.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3WCV2@538999|Clostridiales incertae sedis	186801|Clostridia	U	PFAM Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_3817510_15	1095767.CAHD01000203_gene2328	1.319e-06	59.0	COG0455@1|root,COG0455@2|Bacteria,2HT5K@201174|Actinobacteria	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3817510_6	1137269.AZWL01000042_gene1228	3.761e-13	78.0	COG1261@1|root,COG1261@2|Bacteria,2IR93@201174|Actinobacteria	201174|Actinobacteria	NO	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	SAF
SRR25158416_k127_3817510_1	867845.KI911784_gene1009	3.801e-47	175.0	2E747@1|root,331NN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3817510_7	1463920.JOGB01000070_gene5752	5.537e-13	80.0	COG2453@1|root,COG2453@2|Bacteria,2IHXA@201174|Actinobacteria	201174|Actinobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase
SRR25158416_k127_3817510_3	1463820.JOGW01000022_gene325	3.12e-33	138.0	COG0652@1|root,COG0652@2|Bacteria,2IKZW@201174|Actinobacteria	201174|Actinobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
SRR25158416_k127_3817510_4	1120971.AUCA01000028_gene2335	1.77e-20	96.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,4HG4Q@91061|Bacilli,27ANZ@186823|Alicyclobacillaceae	91061|Bacilli	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158416_k127_3838753_1	886293.Sinac_6706	1.309e-79	276.0	COG3291@1|root,COG3291@2|Bacteria,2J0M9@203682|Planctomycetes	203682|Planctomycetes	M	Domain of unknown function (DUF4394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394
SRR25158416_k127_3838753_0	1382356.JQMP01000001_gene1147	1.593e-82	289.0	COG0683@1|root,COG0683@2|Bacteria,2G7TX@200795|Chloroflexi,27YY0@189775|Thermomicrobia	189775|Thermomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_3838753_2	42256.RradSPS_1001	4.05e-08	56.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
SRR25158416_k127_3839127_14	648757.Rvan_1142	0.0003443	44.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,3N7YM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158416_k127_3839127_12	1313172.YM304_31100	2.918e-19	100.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158416_k127_3839127_2	1380393.JHVP01000006_gene4018	9.463e-163	523.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4ERC3@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_3839127_11	1379698.RBG1_1C00001G1462	1.674e-30	125.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158416_k127_3839127_6	1379698.RBG1_1C00001G1463	2.442e-52	200.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158416_k127_3839127_1	1379698.RBG1_1C00001G1464	4.615e-189	596.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	ltp4	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
SRR25158416_k127_3839127_13	1057002.KB905370_gene1637	2.739e-10	66.0	2DH7Z@1|root,2ZYQ9@2|Bacteria,1PQM8@1224|Proteobacteria,2V2ZX@28211|Alphaproteobacteria,4BJXB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3839127_4	589924.Ferp_2555	3.554e-117	390.0	COG0183@1|root,arCOG01279@2157|Archaea,2Y2G9@28890|Euryarchaeota,246XN@183980|Archaeoglobi	183980|Archaeoglobi	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
SRR25158416_k127_3839127_8	1313172.YM304_23350	9.582e-48	179.0	COG3428@1|root,COG3428@2|Bacteria,2HGDA@201174|Actinobacteria,4CNBH@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158416_k127_3839127_9	292459.STH1400	7.189e-39	156.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158416_k127_3839127_3	525904.Tter_1619	2.952e-145	482.0	COG4770@1|root,COG4770@2|Bacteria,2NQKT@2323|unclassified Bacteria	2|Bacteria	I	Biotin carboxylase C-terminal domain	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3285	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158416_k127_3839127_5	1242864.D187_002182	3.057e-73	254.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158416_k127_3839127_7	1122939.ATUD01000012_gene3154	5.739e-48	180.0	COG2085@1|root,COG2085@2|Bacteria,2ICZ0@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158416_k127_3839127_0	266117.Rxyl_1283	5.235e-226	713.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158416_k127_3839127_10	103733.JNYO01000040_gene3882	2.21e-31	129.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,4E3HK@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM succinate dehydrogenase, cytochrome b556 subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158416_k127_3840694_2	33876.JNXY01000026_gene3363	3.092e-10	62.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DBPZ@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158416_k127_3840694_1	1156844.KB891813_gene6737	1.096e-16	89.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158416_k127_3840694_0	1306990.BARG01000021_gene1942	1.238e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,2IDUR@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3840694_3	471853.Bcav_3431	0.0008146	43.0	28HWT@1|root,2Z82P@2|Bacteria,2IJH8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3987618_11	69279.BG36_21465	3.602e-34	141.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,43H7J@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	penicillin-binding protein	pbpC	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158416_k127_3987618_8	326423.RBAM_009590	2.421e-48	180.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus	91061|Bacilli	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158416_k127_3987618_2	351607.Acel_2034	1.128e-86	302.0	COG5542@1|root,COG5542@2|Bacteria,2HJW5@201174|Actinobacteria,4ETD2@85013|Frankiales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158416_k127_3987618_6	1146883.BLASA_5050	2.88e-61	229.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4ES94@85013|Frankiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158416_k127_3987618_5	546414.Deide_17330	6.565e-69	250.0	arCOG10517@1|root,31Y5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3987618_15	479432.Sros_1277	4.96e-12	74.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria,4EKZ6@85012|Streptosporangiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158416_k127_3987618_3	1304888.ATWF01000001_gene961	2.499e-76	264.0	COG0413@1|root,COG0413@2|Bacteria,2GF51@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158416_k127_3987618_13	29908.U7PZV4	2.463e-24	118.0	KOG0379@1|root,KOG0379@2759|Eukaryota,38C0C@33154|Opisthokonta,3NXSA@4751|Fungi,3QR0G@4890|Ascomycota,211CD@147550|Sordariomycetes,3UTAJ@5151|Ophiostomatales	4751|Fungi	S	Kelch motif	KEL2	GO:0000003,GO:0000133,GO:0000278,GO:0000281,GO:0000746,GO:0000747,GO:0000755,GO:0000910,GO:0000935,GO:0001100,GO:0005575,GO:0005622,GO:0005623,GO:0005628,GO:0005737,GO:0005856,GO:0005874,GO:0005875,GO:0005881,GO:0005933,GO:0005934,GO:0005935,GO:0005937,GO:0005938,GO:0007049,GO:0007088,GO:0007096,GO:0007163,GO:0007346,GO:0008104,GO:0008150,GO:0008360,GO:0009987,GO:0010564,GO:0010639,GO:0010948,GO:0015630,GO:0016020,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022603,GO:0022604,GO:0030427,GO:0030428,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031333,GO:0031500,GO:0032153,GO:0032155,GO:0032187,GO:0032231,GO:0032271,GO:0032272,GO:0032465,GO:0032505,GO:0032506,GO:0032878,GO:0032879,GO:0032886,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0034613,GO:0035371,GO:0035838,GO:0035839,GO:0035840,GO:0036214,GO:0042763,GO:0042764,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043332,GO:0044087,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044463,GO:0044464,GO:0044703,GO:0044764,GO:0045786,GO:0045839,GO:0045930,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051049,GO:0051128,GO:0051129,GO:0051179,GO:0051285,GO:0051286,GO:0051301,GO:0051302,GO:0051493,GO:0051494,GO:0051641,GO:0051704,GO:0051726,GO:0051783,GO:0051784,GO:0060627,GO:0061160,GO:0061172,GO:0061245,GO:0061246,GO:0061640,GO:0065007,GO:0065008,GO:0070507,GO:0070727,GO:0071944,GO:0071963,GO:0072697,GO:0090337,GO:0097427,GO:0099070,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:0110053,GO:0120025,GO:0120038,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902405,GO:1902410,GO:1902486,GO:1902903,GO:1902904,GO:1903047,GO:1904511,GO:1904758,GO:1990151,GO:1990615,GO:1990752,GO:1990778,GO:1990896,GO:2000099,GO:2000100,GO:2000114,GO:2000769,GO:2000771	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_5
SRR25158416_k127_3987618_4	1211815.CBYP010000021_gene3219	6.814e-70	257.0	COG1073@1|root,COG1073@2|Bacteria,2H7CB@201174|Actinobacteria	201174|Actinobacteria	S	COG COG0412 Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis transport and catabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3987618_14	1089455.MOPEL_083_00650	1.267e-22	100.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4F74R@85018|Dermatophilaceae	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158416_k127_3987618_9	1041522.MCOL_V210540	2.206e-43	163.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,232AP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158416_k127_3987618_12	28444.JODQ01000005_gene1248	3.528e-29	119.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4EJZ9@85012|Streptosporangiales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158416_k127_3987618_10	469371.Tbis_3558	6.404e-35	139.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4E3N7@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158416_k127_3987618_0	555779.Dthio_PD0863	3.966e-275	871.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158416_k127_3987618_7	1303518.CCALI_01951	7.774e-55	203.0	COG0177@1|root,COG0177@2|Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158416_k127_3987618_1	1121877.JQKF01000007_gene967	1.897e-187	602.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158416_k127_4038509_3	1459636.NTE_00536	1.014e-07	55.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158416_k127_4038509_0	390989.JOEG01000013_gene2562	2.98e-216	679.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_4038509_2	685778.AORL01000022_gene1572	2.982e-56	200.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4RU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158416_k127_4038509_1	263358.VAB18032_22345	4.166e-70	246.0	COG0395@1|root,COG0395@2|Bacteria,2IPUK@201174|Actinobacteria,4DER9@85008|Micromonosporales	201174|Actinobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_4056538_1	285535.JOEY01000019_gene2400	4.475e-115	383.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_4056538_6	1192034.CAP_0198	1.097e-36	142.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_4056538_7	1210045.ALNP01000035_gene2424	1.307e-22	104.0	COG2259@1|root,COG2259@2|Bacteria,2IMX8@201174|Actinobacteria	201174|Actinobacteria	S	PFAM DoxX family protein	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158416_k127_4056538_3	446470.Snas_3926	1.24e-67	237.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4EYAD@85014|Glycomycetales	201174|Actinobacteria	S	Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158416_k127_4056538_2	1111479.AXAR01000007_gene947	3.864e-91	314.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158416_k127_4056538_0	479432.Sros_6721	2.255e-131	428.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4EFXF@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158416_k127_4056538_5	1089550.ATTH01000001_gene1576	1.022e-50	189.0	COG0652@1|root,COG0652@2|Bacteria,4PM5K@976|Bacteroidetes,1FJNB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
SRR25158416_k127_4056538_4	235985.BBPN01000002_gene4946	2.61e-67	238.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,2NEXV@228398|Streptacidiphilus	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158416_k127_4061248_30	511051.CSE_05130	2.892e-41	163.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
SRR25158416_k127_4061248_21	570268.ANBB01000013_gene3102	2.188e-71	254.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4EM31@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158416_k127_4061248_22	479432.Sros_5996	9.431e-70	257.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4EMAJ@85012|Streptosporangiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158416_k127_4061248_15	1122138.AQUZ01000019_gene8163	1.346e-92	319.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DQD4@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 2, HAAT family	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158416_k127_4061248_13	1122138.AQUZ01000019_gene8164	6.341e-97	323.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPPJ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158416_k127_4061248_6	1122138.AQUZ01000019_gene8165	1.813e-123	417.0	COG4177@1|root,COG4177@2|Bacteria,2I8MK@201174|Actinobacteria,4DRJH@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158416_k127_4061248_9	1128421.JAGA01000002_gene1295	3.337e-108	362.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158416_k127_4061248_12	1128421.JAGA01000002_gene1294	2.694e-103	351.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_4061248_0	351607.Acel_1054	0.0	1138.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERD2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158416_k127_4061248_26	243164.DET0620	1.158e-55	212.0	COG2887@1|root,COG2887@2|Bacteria,2GBU9@200795|Chloroflexi,34CT2@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158416_k127_4061248_24	864564.HMPREF0620_1237	1.427e-59	218.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158416_k127_4061248_32	656024.FsymDg_3065	2.543e-32	136.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4ET0T@85013|Frankiales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158416_k127_4061248_35	28444.JODQ01000001_gene2141	3.162e-21	98.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4EJJN@85012|Streptosporangiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158416_k127_4061248_1	351607.Acel_1029	0.0	1105.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4ERW9@85013|Frankiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158416_k127_4061248_40	211114.JOEF01000016_gene3604	4.993e-06	55.0	2E42E@1|root,32YYX@2|Bacteria,2IQSB@201174|Actinobacteria,4E60P@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	ko:K14201	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	-
SRR25158416_k127_4061248_39	767817.Desgi_3616	2.539e-07	61.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,262G3@186807|Peptococcaceae	186801|Clostridia	D	PFAM DivIVA	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158416_k127_4061248_37	84588.SYNW1295	5.472e-09	61.0	COG0762@1|root,COG0762@2|Bacteria,1G95C@1117|Cyanobacteria,1H1NH@1129|Synechococcus	1117|Cyanobacteria	S	integral membrane protein	ycf19	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158416_k127_4061248_33	1035308.AQYY01000001_gene2338	6.93e-32	132.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158416_k127_4061248_28	1120973.AQXL01000130_gene1260	3.227e-47	178.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,278DI@186823|Alicyclobacillaceae	91061|Bacilli	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158416_k127_4061248_29	264732.Moth_0856	1.002e-44	172.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,42FXU@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158416_k127_4061248_2	465515.Mlut_13570	8.079e-148	477.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,1W8CK@1268|Micrococcaceae	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158416_k127_4061248_16	42256.RradSPS_0328	2.265e-90	321.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4CU1G@84995|Rubrobacteria	84995|Rubrobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_9,SpoIIE
SRR25158416_k127_4061248_34	469383.Cwoe_3448	5.049e-27	115.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158416_k127_4061248_38	2325.TKV_c15400	6.416e-09	65.0	COG1589@1|root,COG1589@2|Bacteria,1V8JW@1239|Firmicutes,24KA8@186801|Clostridia,42GME@68295|Thermoanaerobacterales	186801|Clostridia	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158416_k127_4061248_23	935845.JADQ01000008_gene1918	5.601e-60	220.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRR25158416_k127_4061248_7	1048339.KB913029_gene4575	3.302e-118	396.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4ERUC@85013|Frankiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_4061248_4	68223.JNZY01000002_gene5199	6.486e-131	424.0	COG0451@1|root,COG0451@2|Bacteria,2I2ZM@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158416_k127_4061248_25	1047013.AQSP01000144_gene785	1.846e-59	215.0	COG1208@1|root,COG1208@2|Bacteria,2NPHE@2323|unclassified Bacteria	2|Bacteria	JM	Nucleotidyl transferase	ptmE	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
SRR25158416_k127_4061248_11	1155718.KB891853_gene3248	4.027e-105	355.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158416_k127_4061248_17	477974.Daud_1437	4.193e-87	305.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158416_k127_4061248_18	211114.JOEF01000016_gene3593	2.253e-83	298.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4DXZN@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_4061248_10	106370.Francci3_1412	4.013e-108	360.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4ERUH@85013|Frankiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158416_k127_4061248_8	1944.JOAZ01000025_gene2718	8.477e-111	374.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,419WD@629295|Streptomyces griseus group	201174|Actinobacteria	M	Mur ligase family, catalytic domain	murF	GO:0008150,GO:0040007	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_4061248_3	867903.ThesuDRAFT_01664	1.364e-138	459.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_4061248_5	326424.FRAAL2190	1.104e-127	436.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4ERN7@85013|Frankiales	201174|Actinobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158416_k127_4061248_41	1169161.KB897723_gene4807	0.0006898	49.0	COG2919@1|root,COG2919@2|Bacteria,2I3SE@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158416_k127_4061248_20	300852.55772458	2.609e-75	262.0	COG0275@1|root,COG0275@2|Bacteria,1WJ5G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158416_k127_4061248_31	1089553.Tph_c12550	1.096e-33	134.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,42GA2@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158416_k127_4061248_27	525909.Afer_0684	4.667e-50	183.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158416_k127_4061248_19	56107.Cylst_0426	1.404e-77	277.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
SRR25158416_k127_4061248_36	58123.JOFJ01000022_gene3642	7.928e-13	76.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4EHBC@85012|Streptosporangiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_4061248_14	219305.MCAG_01227	2.566e-95	319.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4D9JV@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158416_k127_4065812_4	565033.GACE_1690	9.032e-51	183.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158416_k127_4065812_5	1231057.AMGD01000115_gene321	9.886e-44	178.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,26E03@186818|Planococcaceae	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_4065812_10	204669.Acid345_0197	2.717e-06	60.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4065812_7	1313172.YM304_04440	1.201e-20	98.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158416_k127_4065812_8	29875.EHK25674	1.162e-13	72.0	2AAWD@1|root,2SAUR@2759|Eukaryota,39YPR@33154|Opisthokonta,3NYJM@4751|Fungi,3R1JE@4890|Ascomycota,215RQ@147550|Sordariomycetes,3TK7W@5125|Hypocreales	4751|Fungi	E	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158416_k127_4065812_1	1121468.AUBR01000056_gene1487	4.191e-83	289.0	COG1277@1|root,COG1277@2|Bacteria,1TQM9@1239|Firmicutes,249MZ@186801|Clostridia,42G3W@68295|Thermoanaerobacterales	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158416_k127_4065812_0	1121468.AUBR01000056_gene1488	2.364e-98	333.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,42ENV@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
SRR25158416_k127_4065812_2	1121468.AUBR01000056_gene1489	8.641e-76	268.0	COG1470@1|root,COG1470@2|Bacteria,1TZ9A@1239|Firmicutes,24C4A@186801|Clostridia,42GG3@68295|Thermoanaerobacterales	186801|Clostridia	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
SRR25158416_k127_4065812_3	1463864.JOGO01000004_gene935	1.102e-53	212.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_4065812_9	1463825.JNXC01000040_gene5132	1.619e-08	61.0	2BGAN@1|root,32A83@2|Bacteria,2GPQS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4065812_6	349124.Hhal_0984	3.255e-27	125.0	COG0500@1|root,COG2226@2|Bacteria,1QYM4@1224|Proteobacteria,1RYUE@1236|Gammaproteobacteria,1WXK3@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_4096807_3	1121468.AUBR01000040_gene1734	5.344e-27	113.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24A9U@186801|Clostridia,42J28@68295|Thermoanaerobacterales	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158416_k127_4096807_2	1382306.JNIM01000001_gene4028	2.504e-85	293.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158416_k127_4096807_1	471852.Tcur_4459	1.403e-88	301.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4EHTN@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158416_k127_4096807_0	1267535.KB906767_gene335	1.897e-118	387.0	COG3508@1|root,COG3508@2|Bacteria,3Y38R@57723|Acidobacteria	57723|Acidobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158416_k127_4147660_0	58344.JOEL01000018_gene5327	4.928e-188	602.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158416_k127_4147660_4	344747.PM8797T_03209	5.138e-14	84.0	COG1621@1|root,COG2706@1|root,COG1621@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
SRR25158416_k127_4147660_2	1385521.N803_08115	8.159e-78	267.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4FFJS@85021|Intrasporangiaceae	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158416_k127_4147660_1	671143.DAMO_0751	3.454e-79	276.0	COG0638@1|root,COG0638@2|Bacteria,2NQJR@2323|unclassified Bacteria	2|Bacteria	O	Proteasome subunit	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158416_k127_4147660_5	671143.DAMO_0690	6.654e-11	66.0	2E9C2@1|root,30ZT9@2|Bacteria,2NRQ4@2323|unclassified Bacteria	2|Bacteria	S	Pup-like protein	-	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158416_k127_4147660_3	405948.SACE_2249	4.49e-29	117.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4DZ25@85010|Pseudonocardiales	201174|Actinobacteria	S	proteasome accessory factor PafA2	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158416_k127_4154026_0	351607.Acel_1301	1.425e-114	383.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4ES0C@85013|Frankiales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158416_k127_4154026_2	373903.Hore_09350	1.369e-67	235.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WAIW@53433|Halanaerobiales	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
SRR25158416_k127_4154026_5	1123386.AUIW01000002_gene1349	9.119e-09	59.0	COG1826@1|root,COG1826@2|Bacteria,1WKJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158416_k127_4154026_4	1283283.ATXA01000002_gene2600	4.275e-28	126.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4ESRS@85013|Frankiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158416_k127_4154026_3	1121877.JQKF01000024_gene2404	4.89e-67	237.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158416_k127_4154026_1	315750.BPUM_2178	2.368e-93	318.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	yqhT	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158416_k127_4163227_6	484770.UFO1_1101	3.135e-16	93.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
SRR25158416_k127_4163227_1	1380390.JIAT01000010_gene3958	3.595e-151	510.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
SRR25158416_k127_4163227_0	1380390.JIAT01000010_gene3958	2.142e-173	581.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
SRR25158416_k127_4163227_7	484770.UFO1_1101	1.168e-15	92.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
SRR25158416_k127_4163227_2	208439.AJAP_28455	1.325e-104	359.0	COG0642@1|root,COG2197@1|root,COG3447@1|root,COG4251@1|root,COG2197@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,COG4251@2|Bacteria,2GJB0@201174|Actinobacteria,4E2NH@85010|Pseudonocardiales	201174|Actinobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	MASE1
SRR25158416_k127_4163227_5	1123258.AQXZ01000006_gene167	5.485e-27	115.0	COG2197@1|root,COG3829@1|root,COG2197@2|Bacteria,COG3829@2|Bacteria,2IDZS@201174|Actinobacteria	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,Response_reg
SRR25158416_k127_4163227_9	1219065.VPR01S_06_02190	0.0001696	54.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,1XWPD@135623|Vibrionales	135623|Vibrionales	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158416_k127_4163227_8	448385.sce5815	4.177e-15	83.0	COG0642@1|root,COG2205@2|Bacteria	448385.sce5815|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4163227_3	222534.KB893717_gene2146	2.919e-100	338.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4ESKC@85013|Frankiales	201174|Actinobacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158416_k127_4163227_4	1303518.CCALI_01929	1.254e-51	190.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRR25158416_k127_4167365_5	390989.JOEG01000003_gene4705	1.614e-71	250.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4D8MX@85008|Micromonosporales	201174|Actinobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158416_k127_4167365_1	266117.Rxyl_2822	1.313e-132	434.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4CPI4@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158416_k127_4167365_8	882083.SacmaDRAFT_4273	1.243e-40	167.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	-	2.7.13.3	ko:K02484,ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_8,Response_reg
SRR25158416_k127_4167365_0	35754.JNYJ01000046_gene3102	2.481e-159	518.0	COG1520@1|root,COG1520@2|Bacteria,2I9S4@201174|Actinobacteria,4D97G@85008|Micromonosporales	201174|Actinobacteria	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158416_k127_4167365_9	608538.HTH_0596	5.203e-18	89.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
SRR25158416_k127_4167365_7	644283.Micau_6169	1.269e-46	180.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4DAHC@85008|Micromonosporales	201174|Actinobacteria	S	Rhomboid family	yggP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158416_k127_4167365_10	1210908.HSB1_37300	3.595e-14	82.0	COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eIF-2B alpha beta delta subunits family	tif2Ba	-	-	-	-	-	-	-	-	-	-	-	IF-2B,NUDIX
SRR25158416_k127_4167365_3	316067.Geob_3554	8.076e-84	300.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158416_k127_4167365_4	1476876.JOJO01000044_gene1245	6.103e-72	252.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria	201174|Actinobacteria	L	formamidopyrimidine-DNA glycosylase	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_4167365_2	1078020.KEK_15378	4.208e-85	289.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,234EX@1762|Mycobacteriaceae	201174|Actinobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_4167365_6	1380390.JIAT01000001_gene4997	4.388e-51	190.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158416_k127_4174534_3	479434.Sthe_0890	6.946e-18	86.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi,27Z3C@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_4174534_1	479434.Sthe_0904	4.624e-66	239.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_4174534_2	309801.trd_1490	2.94e-23	104.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_4174534_0	266117.Rxyl_2466	3.156e-207	651.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158416_k127_4179018_8	351607.Acel_2117	4.991e-119	393.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4ERZT@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158416_k127_4179018_22	745776.DGo_CA2413	8.463e-26	111.0	COG0789@1|root,COG0789@2|Bacteria,1WJ4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM MerR family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158416_k127_4179018_0	926550.CLDAP_07340	0.0	1106.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158416_k127_4179018_17	1095767.CAHD01000030_gene1063	8.593e-53	193.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4F201@85016|Cellulomonadaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158416_k127_4179018_13	1242864.D187_005109	3.459e-90	312.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2X2AQ@28221|Deltaproteobacteria,2Z25Q@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158416_k127_4179018_20	1499967.BAYZ01000009_gene5268	5.087e-41	161.0	COG2220@1|root,COG2220@2|Bacteria,2NPQC@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158416_k127_4179018_9	1382356.JQMP01000003_gene2585	3.429e-116	381.0	COG3892@1|root,COG3892@2|Bacteria,2G87A@200795|Chloroflexi,27Z2I@189775|Thermomicrobia	189775|Thermomicrobia	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2090
SRR25158416_k127_4179018_26	526227.Mesil_3459	8.966e-10	61.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158416_k127_4179018_3	269800.Tfu_3012	2.809e-175	559.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4EFS2@85012|Streptosporangiales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158416_k127_4179018_5	429009.Adeg_0312	2.867e-141	467.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42FB3@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158416_k127_4179018_18	1089553.Tph_c08420	1.235e-45	170.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,42G1V@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158416_k127_4179018_4	1121422.AUMW01000001_gene2355	1.207e-145	478.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158416_k127_4179018_10	234267.Acid_5250	3.317e-111	369.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria	57723|Acidobacteria	F	PFAM SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158416_k127_4179018_25	1463855.JOHV01000062_gene421	3.035e-12	77.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158416_k127_4179018_15	1074488.AGBX01000008_gene2596	1.946e-83	284.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4FCD6@85020|Dermabacteraceae	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158416_k127_4179018_1	469371.Tbis_3339	8.89e-228	730.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DXHH@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158416_k127_4179018_2	570268.ANBB01000033_gene2018	3.983e-176	563.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4EGDA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158416_k127_4179018_12	570268.ANBB01000033_gene2017	3.76e-94	321.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4EH43@85012|Streptosporangiales	201174|Actinobacteria	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158416_k127_4179018_19	926569.ANT_09250	4.303e-42	174.0	COG0642@1|root,COG2205@2|Bacteria,2G6KS@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF,HATPase_c,HisKA
SRR25158416_k127_4179018_16	479434.Sthe_2399	9.157e-76	265.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,27XQF@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158416_k127_4179018_14	1121928.AUHE01000005_gene1028	7.426e-90	324.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4GBRZ@85026|Gordoniaceae	201174|Actinobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158416_k127_4179018_7	469371.Tbis_3331	7.766e-123	407.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4E0CR@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158416_k127_4179018_11	35754.JNYJ01000016_gene9416	7.794e-101	341.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4D8EX@85008|Micromonosporales	201174|Actinobacteria	C	dehydrogenase, E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158416_k127_4179018_6	997346.HMPREF9374_0320	2.14e-128	420.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27BNG@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158416_k127_4179018_21	67315.JOBD01000040_gene1721	1.27e-40	164.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4179018_24	710696.Intca_3222	9.683e-23	98.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4FI4Q@85021|Intrasporangiaceae	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_4179018_28	3880.AES87815	5.504e-06	54.0	2D08W@1|root,2SD7U@2759|Eukaryota,37XFR@33090|Viridiplantae,3GMII@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface	psbM	-	-	ko:K02714	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbM
SRR25158416_k127_4179018_23	35754.JNYJ01000003_gene6534	9.092e-24	108.0	28UI1@1|root,31V7R@2|Bacteria,2H6IC@201174|Actinobacteria,4DJH7@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4179018_27	368407.Memar_2421	2.805e-07	57.0	COG2133@1|root,COG3794@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,2XT1Q@28890|Euryarchaeota	28890|Euryarchaeota	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,GSDH
SRR25158416_k127_4190254_1	1304880.JAGB01000001_gene725	4.787e-116	384.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158416_k127_4190254_2	1429046.RR21198_0273	6.429e-39	152.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4FUNH@85025|Nocardiaceae	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158416_k127_4190254_3	742741.HMPREF9475_03285	0.0004177	51.0	COG2843@1|root,COG2843@2|Bacteria,1V20N@1239|Firmicutes,24AI2@186801|Clostridia,2232U@1506553|Lachnoclostridium	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158416_k127_4190254_0	292459.STH586	1.168e-161	524.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158416_k127_419943_1	1407650.BAUB01000007_gene1622	4.481e-83	289.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1G07C@1117|Cyanobacteria	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2
SRR25158416_k127_419943_0	391625.PPSIR1_25986	2.144e-85	301.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169,iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
SRR25158416_k127_419943_8	497964.CfE428DRAFT_6497	2.219e-05	50.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158416_k127_419943_4	1128421.JAGA01000002_gene1502	3.114e-68	244.0	COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU05900	AIRS,AIRS_C
SRR25158416_k127_419943_3	932678.THERU_05380	1.612e-76	265.0	COG0351@1|root,COG0351@2|Bacteria	2|Bacteria	H	phosphomethylpyrimidine kinase activity	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00941,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI
SRR25158416_k127_419943_7	709986.Deima_0107	8.134e-11	69.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158416_k127_419943_2	266117.Rxyl_1658	9.711e-77	266.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_419943_6	883066.HMPREF9233_01454	9.349e-27	110.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D6AF@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158416_k127_419943_5	196162.Noca_1378	1.671e-57	208.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DNMY@85009|Propionibacteriales	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158416_k127_4235180_0	28444.JODQ01000007_gene5159	3.562e-176	587.0	COG2866@1|root,COG2866@2|Bacteria,2IAU2@201174|Actinobacteria,4EFJH@85012|Streptosporangiales	201174|Actinobacteria	E	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Peptidase_M14
SRR25158416_k127_4235180_3	298653.Franean1_5788	1.659e-56	201.0	COG2514@1|root,COG2514@2|Bacteria,2GUZK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158416_k127_4235180_4	313596.RB2501_12217	1.317e-41	157.0	COG0346@1|root,COG0346@2|Bacteria,4P85Q@976|Bacteroidetes	976|Bacteroidetes	C	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_4235180_1	523791.Kkor_1008	1.827e-79	292.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158416_k127_4235180_5	555088.DealDRAFT_1743	5.56e-32	144.0	COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,25CFE@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158416_k127_4235180_2	1157637.KB892124_gene634	1.841e-62	221.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
SRR25158416_k127_423595_0	298654.FraEuI1c_1807	3.796e-103	348.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4ERSX@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_4272172_2	330214.NIDE3110	5.312e-32	127.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158416_k127_4272172_1	251221.35212182	5.504e-80	276.0	COG0667@1|root,COG0667@2|Bacteria,1G1J4@1117|Cyanobacteria	1117|Cyanobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_4272172_3	5145.XP_001903369.1	1.209e-22	102.0	2CXX5@1|root,2S0DV@2759|Eukaryota,3A0MP@33154|Opisthokonta,3P2GJ@4751|Fungi,3QUWC@4890|Ascomycota,21AWP@147550|Sordariomycetes,3UBCM@5139|Sordariales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRR25158416_k127_4272172_0	306281.AJLK01000098_gene3954	1.878e-180	580.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1JHXE@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_4272172_4	471852.Tcur_2891	5.972e-07	53.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4EJGT@85012|Streptosporangiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_472071_0	1206101.AZXC01000009_gene381	1.469e-244	768.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158416_k127_472071_3	1120934.KB894454_gene1879	9.485e-35	140.0	COG5637@1|root,COG5637@2|Bacteria,2GZK6@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_472071_1	656024.FsymDg_3273	1.135e-112	371.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158416_k127_472071_2	1121430.JMLG01000012_gene1991	9.134e-62	224.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR25158416_k127_49749_4	436114.SYO3AOP1_0802	1.088e-46	176.0	COG0483@1|root,COG0483@2|Bacteria,2G3ZG@200783|Aquificae	200783|Aquificae	G	Inositol monophosphatase	-	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158416_k127_49749_3	593907.Celgi_0800	3.158e-60	211.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4F18F@85016|Cellulomonadaceae	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158416_k127_49749_2	396014.BF93_14335	1.135e-64	226.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4FBD7@85020|Dermabacteraceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158416_k127_49749_0	525909.Afer_0395	9.389e-314	975.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CMTM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158416_k127_49749_1	351607.Acel_0304	4.915e-139	447.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158416_k127_53549_1	1123229.AUBC01000005_gene614	0.0002874	51.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2TT0T@28211|Alphaproteobacteria,3JTVU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_53549_0	469383.Cwoe_2515	2.836e-149	494.0	COG1190@1|root,COG2898@1|root,COG1190@2|Bacteria,COG2898@2|Bacteria,2GKE0@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF2156,tRNA-synt_2,tRNA_anti-codon
SRR25158416_k127_542160_1	926569.ANT_28670	7.626e-71	256.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158416_k127_542160_2	543632.JOJL01000017_gene9929	0.0008703	43.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158416_k127_542160_0	485913.Krac_2463	1.662e-222	705.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158416_k127_61090_4	1173028.ANKO01000216_gene6189	1.842e-16	94.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Calx-beta,Chlam_PMP,DUF4347,HemolysinCabind
SRR25158416_k127_61090_2	357808.RoseRS_2348	1.003e-45	189.0	COG2885@1|root,COG5492@1|root,COG2885@2|Bacteria,COG5492@2|Bacteria,2GBMA@200795|Chloroflexi,377D0@32061|Chloroflexia	32061|Chloroflexia	M	Polymorphic membrane protein, Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_61090_0	471852.Tcur_3574	7.726e-107	355.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4EGI3@85012|Streptosporangiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158416_k127_61090_1	446468.Ndas_0256	1.381e-79	273.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4EFT7@85012|Streptosporangiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158416_k127_61090_3	1120959.ATXF01000009_gene730	2.14e-29	128.0	COG4747@1|root,COG4747@2|Bacteria,2HTE7@201174|Actinobacteria,4FT5U@85023|Microbacteriaceae	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_622041_10	219305.MCAG_00294	4.038e-09	64.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,LRR_5,Laminin_G_3
SRR25158416_k127_622041_7	1032480.MLP_12160	4.558e-19	94.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4DS73@85009|Propionibacteriales	201174|Actinobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158416_k127_622041_1	573413.Spirs_0261	4.835e-168	546.0	COG0442@1|root,COG0442@2|Bacteria,2J5HF@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158416_k127_622041_11	1121946.AUAX01000012_gene6500	7.738e-05	50.0	2ER41@1|root,33IPK@2|Bacteria,2IKQ6@201174|Actinobacteria,4DE2S@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_622041_5	429009.Adeg_1666	4.871e-35	139.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,42GU2@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158416_k127_622041_2	1229780.BN381_330069	6.309e-113	379.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,3UW9A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158416_k127_622041_9	525903.Taci_0995	1.019e-16	85.0	COG2740@1|root,COG2740@2|Bacteria,3TBIS@508458|Synergistetes	508458|Synergistetes	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158416_k127_622041_0	1121468.AUBR01000029_gene1569	1.414e-215	689.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158416_k127_622041_8	330214.NIDE4132	9.478e-18	86.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158416_k127_622041_6	1504319.GM45_4595	1.626e-23	104.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,3UWR7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158416_k127_622041_3	1146883.BLASA_3740	2.991e-73	259.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4ESKW@85013|Frankiales	201174|Actinobacteria	S	PFAM phosphoesterase RecJ domain protein	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158416_k127_622041_4	397278.JOJN01000001_gene2644	3.074e-41	157.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4DPKY@85009|Propionibacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158416_k127_649223_0	263358.VAB18032_27071	2.489e-109	396.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158416_k127_649223_1	500153.JOEK01000001_gene3975	8.82e-12	72.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158416_k127_653251_0	1048339.KB913029_gene2528	2.108e-184	603.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158416_k127_653251_1	479431.Namu_0799	4.506e-110	360.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4ES91@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_668978_1	644966.Tmar_0414	1.421e-36	152.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_668978_0	929712.KI912613_gene1139	5.638e-72	261.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158416_k127_694153_0	667014.Thein_1592	8.439e-106	356.0	COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158416_k127_694153_1	580340.Tlie_1873	2.476e-57	208.0	COG0537@1|root,COG0537@2|Bacteria,3TB29@508458|Synergistetes	508458|Synergistetes	FG	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158416_k127_694153_2	1460634.JCM19037_3596	9.931e-41	170.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_694153_3	240015.ACP_1356	0.000105	54.0	COG4409@1|root,COG4409@2|Bacteria,3Y8VS@57723|Acidobacteria	57723|Acidobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_700679_6	1380390.JIAT01000010_gene3415	5.76e-25	109.0	COG0824@1|root,COG0824@2|Bacteria,2II31@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158416_k127_700679_2	479435.Kfla_1675	5.288e-86	292.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4DN3M@85009|Propionibacteriales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158416_k127_700679_4	33876.JNXY01000025_gene5399	2.599e-48	189.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4DBWZ@85008|Micromonosporales	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158416_k127_700679_1	1382306.JNIM01000001_gene1964	5.451e-88	304.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	ycbU	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158416_k127_700679_7	710111.FraQA3DRAFT_3398	2.187e-11	77.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,2I4BA@201174|Actinobacteria,4EXHK@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158416_k127_700679_0	219305.MCAG_00296	1.716e-150	488.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158416_k127_700679_5	479434.Sthe_0449	1.989e-38	157.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	2|Bacteria	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Cu_amine_oxidN1,FAD_oxidored,Glyco_hydro_18,Hydrolase_2,Polysacc_deac_1,SLH
SRR25158416_k127_775042_14	1430440.MGMSRv2_3429	4.196e-06	52.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,2U5XC@28211|Alphaproteobacteria,2JT9V@204441|Rhodospirillales	204441|Rhodospirillales	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158416_k127_775042_8	312284.A20C1_08203	3.951e-58	215.0	COG1228@1|root,COG1228@2|Bacteria,2IISK@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158416_k127_775042_4	1122138.AQUZ01000019_gene8187	6.654e-133	437.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_775042_2	1122138.AQUZ01000019_gene8187	2.944e-169	544.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_775042_0	222534.KB893783_gene5230	3.347e-292	910.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4ERJA@85013|Frankiales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158416_k127_775042_13	42256.RradSPS_0526	8.925e-25	108.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158416_k127_775042_12	1125863.JAFN01000001_gene2910	4.349e-28	126.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158416_k127_775042_9	469371.Tbis_1479	1.993e-53	195.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4DYSR@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158416_k127_775042_3	1386089.N865_00615	4.798e-158	512.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4FF0W@85021|Intrasporangiaceae	201174|Actinobacteria	J	in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158416_k127_775042_1	1120936.KB907210_gene5640	5.718e-235	766.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4EH6R@85012|Streptosporangiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158416_k127_775042_11	1313172.YM304_09420	2.337e-48	181.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158416_k127_775042_7	1348663.KCH_02150	8.332e-65	231.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,2M2I7@2063|Kitasatospora	201174|Actinobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158416_k127_775042_6	335543.Sfum_1389	5.549e-70	244.0	COG1811@1|root,COG1811@2|Bacteria,1MX1D@1224|Proteobacteria,42S9G@68525|delta/epsilon subdivisions,2WNUQ@28221|Deltaproteobacteria,2MQH1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158416_k127_775042_5	246194.CHY_0506	1.785e-94	317.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,42EP4@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM ABC transporter related	glnQ	-	3.6.3.21	ko:K02028,ko:K10041,ko:K17076	ko02010,map02010	M00228,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.20	-	-	ABC_tran
SRR25158416_k127_775042_10	266117.Rxyl_0500	1.085e-50	188.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CU2C@84995|Rubrobacteria	84995|Rubrobacteria	P	Amino acid ABC transporter, permease protein, 3-TM	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158416_k127_812355_1	1379698.RBG1_1C00001G0804	1.112e-90	306.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_812355_0	1120950.KB892746_gene3520	3.5e-98	331.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158416_k127_812355_4	1160137.KB907307_gene1305	2.097e-12	72.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4G19C@85025|Nocardiaceae	201174|Actinobacteria	T	cheY-homologous receiver domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_812355_3	1476876.JOJO01000011_gene3379	1.742e-43	162.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_812355_2	469383.Cwoe_4711	8.656e-52	187.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158416_k127_814306_0	1121272.KB903249_gene2254	3.532e-69	251.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
SRR25158416_k127_814306_2	1246448.ANAZ01000032_gene5693	1.756e-50	199.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4EI3T@85012|Streptosporangiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_814306_1	1246448.ANAZ01000032_gene5693	2.556e-52	204.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4EI3T@85012|Streptosporangiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158416_k127_814306_3	479433.Caci_3065	8.591e-19	93.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158416_k127_826712_2	309799.DICTH_1914	2.996e-113	378.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158416_k127_826712_3	591159.ACEZ01000015_gene890	1.103e-90	311.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_826712_7	926569.ANT_28190	3.637e-38	157.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	Apolipoprotein,RmuC
SRR25158416_k127_826712_5	383372.Rcas_1525	3.662e-62	221.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158416_k127_826712_8	2002.JOEQ01000010_gene6339	3.505e-26	115.0	2DHRC@1|root,32U9K@2|Bacteria,2II2K@201174|Actinobacteria,4EQWW@85012|Streptosporangiales	201174|Actinobacteria	S	Family of unknown function (DUF5319)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5319
SRR25158416_k127_826712_0	494419.ALPM01000115_gene765	7.697e-157	528.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,1W81P@1268|Micrococcaceae	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158416_k127_826712_4	469371.Tbis_2990	2.567e-79	273.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4E10U@85010|Pseudonocardiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158416_k127_826712_1	880072.Desac_0006	2.069e-152	494.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2MRAX@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158416_k127_826712_6	1095769.CAHF01000011_gene2601	5.897e-39	147.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158416_k127_866012_0	1380347.JNII01000002_gene3951	6.095e-97	329.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4ERYY@85013|Frankiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158416_k127_866012_3	234621.RER_24690	1.741e-19	92.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4G1R8@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158416_k127_866012_2	1122622.ATWJ01000007_gene1845	2.933e-36	142.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4FH32@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158416_k127_866012_1	1120950.KB892769_gene5387	5.079e-54	197.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4DPWD@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158416_k127_889531_6	1121035.AUCH01000003_gene1201	4.948e-22	98.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2VHX9@28216|Betaproteobacteria,2KUEJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158416_k127_889531_3	1463841.JOIR01000013_gene2370	2.734e-53	199.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria	201174|Actinobacteria	H	Pfam UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158416_k127_889531_0	1123508.JH636444_gene5358	6.248e-189	601.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158416_k127_889531_5	485913.Krac_2639	3.07e-26	117.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158416_k127_889531_4	485913.Krac_2638	3.054e-26	120.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158416_k127_889531_1	485913.Krac_2637	6.34e-178	572.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158416_k127_889531_2	485913.Krac_6021	5.836e-58	216.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_924546_5	266117.Rxyl_1977	7.706e-43	170.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158416_k127_924546_3	234267.Acid_3179	1.692e-63	229.0	COG0181@1|root,COG0181@2|Bacteria,3Y3RY@57723|Acidobacteria	57723|Acidobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158416_k127_924546_1	479432.Sros_0548	9.021e-88	308.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4EH7H@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158416_k127_924546_2	2045.KR76_03655	1.739e-82	280.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4DPX5@85009|Propionibacteriales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158416_k127_924546_6	517417.Cpar_1797	5.811e-12	68.0	COG0526@1|root,COG0526@2|Bacteria,1FFQK@1090|Chlorobi	1090|Chlorobi	CO	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158416_k127_924546_7	926569.ANT_02430	1.016e-10	72.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_924546_0	635013.TherJR_2695	5.558e-100	344.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,2608N@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	2.3.1.40,6.2.1.20,6.2.1.3,6.2.1.48	ko:K01897,ko:K02182,ko:K05939	ko00061,ko00071,ko00564,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00564,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R01406,R04864	RC00004,RC00014,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_924546_4	345341.KUTG_05707	5.01e-45	178.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4DX95@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158416_k127_924546_8	429009.Adeg_2019	0.0001259	47.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,42GI7@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158416_k127_987359_0	479435.Kfla_3708	0.0	1033.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4DP39@85009|Propionibacteriales	201174|Actinobacteria	HJM	RimK-like ATP-grasp domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158416_k127_987359_2	477641.MODMU_2617	2.013e-68	244.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4ERMG@85013|Frankiales	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158416_k127_987359_1	110319.CF8_2113	6.029e-145	479.0	COG0769@1|root,COG0769@2|Bacteria,2GME3@201174|Actinobacteria,4DPYG@85009|Propionibacteriales	201174|Actinobacteria	M	Mur ligase middle domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,TPR_5
SRR25158416_k127_987359_3	1150864.MILUP08_40545	3.347e-26	112.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4DBIU@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
## 1535 queries scanned
## Total time (seconds): 3.370195150375366
## Rate: 455.46 q/s